LOCUS       DAVBEM010000001        97484 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVBEM010000001 DAVBEM010000000
VERSION     DAVBEM010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 97484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 97484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..97484
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.001"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            <1..223
                     /locus_tag="VQ548_000001"
     CDS             <1..223
                     /locus_tag="VQ548_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2652943.1"
                     /translation="QAQTPRKSSKLKPLTAEDKACNHVLSKERSKVENIFAKVKTLKM
                     FSTTYRNHRKRFGLRMNLIVGIINHELGF"
     gene            240..818
                     /locus_tag="VQ548_000002"
                     /pseudo
     CDS             240..818
                     /locus_tag="VQ548_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            831..1001
                     /locus_tag="VQ548_000003"
     CDS             831..1001
                     /locus_tag="VQ548_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2652944.1"
                     /translation="MKKENEYVILTIASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(1507..2853)
                     /gene="gdhA"
                     /locus_tag="VQ548_000004"
     CDS             complement(1507..2853)
                     /gene="gdhA"
                     /locus_tag="VQ548_000004"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HET2652945.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            3194..3928
                     /locus_tag="VQ548_000005"
                     /pseudo
     CDS             3194..3928
                     /locus_tag="VQ548_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3925..4143
                     /locus_tag="VQ548_000006"
     CDS             3925..4143
                     /locus_tag="VQ548_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2652946.1"
                     /translation="MSISPRFEALEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     TAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(4200..4484)
                     /locus_tag="VQ548_000007"
     CDS             complement(4200..4484)
                     /locus_tag="VQ548_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HET2652947.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(4538..5473)
                     /locus_tag="VQ548_000008"
     CDS             complement(4538..5473)
                     /locus_tag="VQ548_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HET2652948.1"
                     /translation="MEICQQILEKIKEYNTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNVTDAETAAIVGAPGRIDSVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            5577..6020
                     /locus_tag="VQ548_000009"
     CDS             5577..6020
                     /locus_tag="VQ548_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HET2652949.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            6136..6402
                     /locus_tag="VQ548_000010"
     CDS             6136..6402
                     /locus_tag="VQ548_000010"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HET2652950.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSYILKRSRDYQDQNIK"
     gene            6399..6773
                     /gene="crcB"
                     /locus_tag="VQ548_000011"
     CDS             6399..6773
                     /gene="crcB"
                     /locus_tag="VQ548_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET2652951.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYFSLV
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            6767..7096
                     /gene="crcB"
                     /locus_tag="VQ548_000012"
     CDS             6767..7096
                     /gene="crcB"
                     /locus_tag="VQ548_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET2652952.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            7215..7562
                     /gene="rplS"
                     /locus_tag="VQ548_000013"
     CDS             7215..7562
                     /gene="rplS"
                     /locus_tag="VQ548_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HET2652953.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            7605..7676
                     /locus_tag="VQ548_000014"
     tRNA            7605..7676
                     /locus_tag="VQ548_000014"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7638..7640,aa:Arg,seq:cct)
     gene            complement(7843..8841)
                     /locus_tag="VQ548_000015"
     CDS             complement(7843..8841)
                     /locus_tag="VQ548_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HET2652954.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNELECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLTVVELKTILSKHN
                     LATSGKKAELITRIINNVNIDNLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDISMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(8884..9690)
                     /gene="yidA"
                     /locus_tag="VQ548_000016"
     CDS             complement(8884..9690)
                     /gene="yidA"
                     /locus_tag="VQ548_000016"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HET2652955.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRPMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(9703..11007)
                     /locus_tag="VQ548_000017"
     CDS             complement(9703..11007)
                     /locus_tag="VQ548_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET2652956.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTVTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPVENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKNFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESQNPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            11079..11456
                     /locus_tag="VQ548_000018"
     CDS             11079..11456
                     /locus_tag="VQ548_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HET2652957.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELMMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            11547..11879
                     /locus_tag="VQ548_000019"
     CDS             11547..11879
                     /locus_tag="VQ548_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HET2652958.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            11891..13462
                     /gene="ffh"
                     /locus_tag="VQ548_000020"
     CDS             11891..13462
                     /gene="ffh"
                     /locus_tag="VQ548_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HET2652959.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(13657..14940)
                     /locus_tag="VQ548_000021"
     CDS             complement(13657..14940)
                     /locus_tag="VQ548_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HET2652960.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(15243..15956)
                     /gene="rsmG"
                     /locus_tag="VQ548_000022"
     CDS             complement(15243..15956)
                     /gene="rsmG"
                     /locus_tag="VQ548_000022"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HET2652961.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            16050..16610
                     /locus_tag="VQ548_000023"
     CDS             16050..16610
                     /locus_tag="VQ548_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HET2652962.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTSEEEKSVPKVDFSGLGD"
     gene            16612..17511
                     /gene="htpX"
                     /locus_tag="VQ548_000024"
     CDS             16612..17511
                     /gene="htpX"
                     /locus_tag="VQ548_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HET2652963.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(17555..19114)
                     /locus_tag="VQ548_000025"
     CDS             complement(17555..19114)
                     /locus_tag="VQ548_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2652964.1"
                     /translation="MHYRHSRKGNSMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKVPEDLKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKTAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLAQELQLTVRGQEKIGIIGPNGVGKSTLLAKLQQLLNDKREISLGFMPQDYHK
                     KLQLDLSSIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(19353..19670)
                     /locus_tag="VQ548_000026"
     CDS             complement(19353..19670)
                     /locus_tag="VQ548_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET2652965.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSPLIGLGSLKLNDQARTAWRNYDKIHYEHVKHVLSLYGPV
                     FGF"
     gene            19849..20391
                     /locus_tag="VQ548_000027"
     CDS             19849..20391
                     /locus_tag="VQ548_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HET2652966.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            20391..21020
                     /gene="nth"
                     /locus_tag="VQ548_000028"
     CDS             20391..21020
                     /gene="nth"
                     /locus_tag="VQ548_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HET2652967.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            21231..21752
                     /gene="pyrR"
                     /locus_tag="VQ548_000029"
     CDS             21231..21752
                     /gene="pyrR"
                     /locus_tag="VQ548_000029"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HET2652968.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            21771..22694
                     /locus_tag="VQ548_000030"
     CDS             21771..22694
                     /locus_tag="VQ548_000030"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HET2652969.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGKFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            22744..23823
                     /gene="carA"
                     /locus_tag="VQ548_000031"
     CDS             22744..23823
                     /gene="carA"
                     /locus_tag="VQ548_000031"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HET2652970.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            24135..27311
                     /gene="carB"
                     /locus_tag="VQ548_000032"
     CDS             24135..27311
                     /gene="carB"
                     /locus_tag="VQ548_000032"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HET2652971.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(27586..28395)
                     /locus_tag="VQ548_000033"
     CDS             complement(27586..28395)
                     /locus_tag="VQ548_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2652972.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDQFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(28397..29200)
                     /locus_tag="VQ548_000034"
     CDS             complement(28397..29200)
                     /locus_tag="VQ548_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2652973.1"
                     /translation="MKQLTVEDAKQIELEILNYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPMDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRLVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSATFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(29210..30697)
                     /gene="tacF"
                     /locus_tag="VQ548_000035"
     CDS             complement(29210..30697)
                     /gene="tacF"
                     /locus_tag="VQ548_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HET2652974.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGDILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            31033..31740
                     /locus_tag="VQ548_000036"
     CDS             31033..31740
                     /locus_tag="VQ548_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HET2652975.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDSIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            31745..32767
                     /locus_tag="VQ548_000037"
     CDS             31745..32767
                     /locus_tag="VQ548_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET2652976.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            32784..33653
                     /gene="licA"
                     /locus_tag="VQ548_000038"
     CDS             32784..33653
                     /gene="licA"
                     /locus_tag="VQ548_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HET2652977.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            33643..34521
                     /locus_tag="VQ548_000039"
     CDS             33643..34521
                     /locus_tag="VQ548_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET2652978.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            34533..35222
                     /locus_tag="VQ548_000040"
     CDS             34533..35222
                     /locus_tag="VQ548_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HET2652979.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQNIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     HKLEEILKNEN"
     gene            35320..36168
                     /gene="dprA"
                     /locus_tag="VQ548_000041"
     CDS             35320..36168
                     /gene="dprA"
                     /locus_tag="VQ548_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HET2652980.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            37052..38095
                     /locus_tag="VQ548_000042"
     CDS             37052..38095
                     /locus_tag="VQ548_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HET2652981.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            38262..40349
                     /gene="topA"
                     /locus_tag="VQ548_000043"
     CDS             38262..40349
                     /gene="topA"
                     /locus_tag="VQ548_000043"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HET2652982.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            40570..40929
                     /locus_tag="VQ548_000044"
     CDS             40570..40929
                     /locus_tag="VQ548_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HET2652983.1"
                     /translation="MRIIYLIIGFLSLTLAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQAYVADFRETKSIARERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            41022..41654
                     /locus_tag="VQ548_000045"
     CDS             41022..41654
                     /locus_tag="VQ548_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HET2652984.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            41698..42354
                     /locus_tag="VQ548_000046"
     CDS             41698..42354
                     /locus_tag="VQ548_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HET2652985.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVYMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            42373..43467
                     /locus_tag="VQ548_000047"
     CDS             42373..43467
                     /locus_tag="VQ548_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HET2652986.1"
                     /translation="MNFQLAKYSLLKRFLENIGFTTLEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKILLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALVDKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNAAGLDFDVLKASA
                     IVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            43479..44516
                     /gene="leuB"
                     /locus_tag="VQ548_000048"
                     /pseudo
     CDS             43479..44516
                     /gene="leuB"
                     /locus_tag="VQ548_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            44513..44782
                     /locus_tag="VQ548_000049"
     CDS             44513..44782
                     /locus_tag="VQ548_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HET2652987.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKSKARRRVWRIPEKILLIL
                     AFTFGGFGAWLAGIIFHHKTRKWYFKIVWFLGMVTTLVALYFIWR"
     gene            44786..45145
                     /gene="leuD"
                     /locus_tag="VQ548_000050"
     CDS             44786..45145
                     /gene="leuD"
                     /locus_tag="VQ548_000050"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HET2652988.1"
                     /translation="MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            45307..45875
                     /locus_tag="VQ548_000051"
                     /pseudo
     CDS             45307..45875
                     /locus_tag="VQ548_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771122.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            45969..46034
                     /locus_tag="VQ548_000052"
                     /pseudo
     CDS             45969..46034
                     /locus_tag="VQ548_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            46197..48128
                     /locus_tag="VQ548_000053"
     CDS             46197..48128
                     /locus_tag="VQ548_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HET2652989.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELMSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNESDENDDADY"
     gene            48115..49467
                     /locus_tag="VQ548_000054"
     CDS             48115..49467
                     /locus_tag="VQ548_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HET2652990.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKKQKILETINQEIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEMGNL
                     AGYGALLKKWSIQIPQKSSSYSAFCKMMENSDYSAFCKMMENSEENFKAIIDEEVGRK
                     "
     gene            49642..50628
                     /locus_tag="VQ548_000055"
     CDS             49642..50628
                     /locus_tag="VQ548_000055"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HET2652991.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKQMHDQGLIASISVGVKDYEY
                     DFVSQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            50692..50763
                     /locus_tag="VQ548_000056"
     tRNA            50692..50763
                     /locus_tag="VQ548_000056"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:50725..50727,aa:Arg,seq:ccg)
     gene            50946..51644
                     /locus_tag="VQ548_000057"
     CDS             50946..51644
                     /locus_tag="VQ548_000057"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HET2652992.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            51635..55174
                     /gene="smc"
                     /locus_tag="VQ548_000058"
     CDS             51635..55174
                     /gene="smc"
                     /locus_tag="VQ548_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HET2652993.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKSEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAITVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDAVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLRSEEAALKTLQDQMATLTERLEVIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQDRLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRYLQSQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNIEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKDRFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            55171..55965
                     /locus_tag="VQ548_000059"
     CDS             55171..55965
                     /locus_tag="VQ548_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2652994.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGETWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKDQSVIAYMEGL"
     gene            55965..56783
                     /locus_tag="VQ548_000060"
     CDS             55965..56783
                     /locus_tag="VQ548_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2652995.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKATLKAASDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGHEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            56787..58007
                     /gene="ftsY"
                     /locus_tag="VQ548_000061"
     CDS             56787..58007
                     /gene="ftsY"
                     /locus_tag="VQ548_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HET2652996.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAVLEESQDSEPAVGVSQEEIEELPEEEKLEHEGTIEENNSEVLEAERPQTEETVQ
                     EKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEELLIMSDVGVQVASNLTEELR
                     YEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQDNLTVMLFVGVNGVGKTTS
                     IGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVDVPVVTGPEKADPASVVFDG
                     MERAVAEGIDILMIDTAGRLQNKDNLMTELEKIGRIIKRVVPEAPHETFLALDASTGQ
                     NALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREELNIPVKLIGFGEKIDDIGEF
                     NSENFMKGLLEGLI"
     gene            complement(58053..59540)
                     /locus_tag="VQ548_000062"
     CDS             complement(58053..59540)
                     /locus_tag="VQ548_000062"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HET2652997.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPAIFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRSVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRFE"
     gene            complement(59689..60429)
                     /locus_tag="VQ548_000063"
     CDS             complement(59689..60429)
                     /locus_tag="VQ548_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2652998.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDNLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(60429..62594)
                     /locus_tag="VQ548_000064"
     CDS             complement(60429..62594)
                     /locus_tag="VQ548_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET2652999.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            62767..63720
                     /locus_tag="VQ548_000065"
     CDS             62767..63720
                     /locus_tag="VQ548_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2653000.1"
                     /translation="MKNKRIFKDFQASKMNLNLYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENCLSNLLKGFSLGLALFLLTLLSLVVLGQYRLESIHLNPYYLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            63797..65785
                     /gene="uvrB"
                     /locus_tag="VQ548_000066"
     CDS             63797..65785
                     /gene="uvrB"
                     /locus_tag="VQ548_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HET2653001.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            65795..66358
                     /locus_tag="VQ548_000067"
     CDS             65795..66358
                     /locus_tag="VQ548_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2653002.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKTNDGYYQINGNS"
     gene            66324..66812
                     /locus_tag="VQ548_000068"
     CDS             66324..66812
                     /locus_tag="VQ548_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2653003.1"
                     /translation="MTVIIKSMETPEEIEGKPLVHWQTWREAYDGLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAMDGMKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LIKAALIALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDEQEKILELGKPIKEKRMVFY
                     SK"
     gene            66885..67352
                     /locus_tag="VQ548_000069"
     CDS             66885..67352
                     /locus_tag="VQ548_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET2653004.1"
                     /translation="MSRAQLTILTNICLIEDLEAQRVVMQYRAPETNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVVCYKATEFSGTLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMEASDKSEFFYPRRTEDDWEKKIF"
     gene            complement(67349..67864)
                     /locus_tag="VQ548_000070"
     CDS             complement(67349..67864)
                     /locus_tag="VQ548_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HET2653005.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFKPLSELTDGVHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(67876..68403)
                     /locus_tag="VQ548_000071"
     CDS             complement(67876..68403)
                     /locus_tag="VQ548_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2653006.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGSLYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(68681..69244)
                     /locus_tag="VQ548_000072"
     CDS             complement(68681..69244)
                     /locus_tag="VQ548_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2653007.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(69228..69779)
                     /gene="coaC"
                     /locus_tag="VQ548_000073"
     CDS             complement(69228..69779)
                     /gene="coaC"
                     /locus_tag="VQ548_000073"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HET2653008.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(69791..70480)
                     /gene="coaB"
                     /locus_tag="VQ548_000074"
     CDS             complement(69791..70480)
                     /gene="coaB"
                     /locus_tag="VQ548_000074"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HET2653009.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            70710..72380
                     /locus_tag="VQ548_000075"
     CDS             70710..72380
                     /locus_tag="VQ548_000075"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HET2653010.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNALSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            72708..73883
                     /gene="mutY"
                     /locus_tag="VQ548_000076"
     CDS             72708..73883
                     /gene="mutY"
                     /locus_tag="VQ548_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HET2653011.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     LIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            73938..74642
                     /locus_tag="VQ548_000077"
     CDS             73938..74642
                     /locus_tag="VQ548_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2653012.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            74635..75984
                     /gene="vicK"
                     /locus_tag="VQ548_000078"
     CDS             74635..75984
                     /gene="vicK"
                     /locus_tag="VQ548_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HET2653013.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            75986..76795
                     /locus_tag="VQ548_000079"
     CDS             75986..76795
                     /locus_tag="VQ548_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET2653014.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            76886..77128
                     /locus_tag="VQ548_000080"
     CDS             76886..77128
                     /locus_tag="VQ548_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HET2653015.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            77130..77384
                     /locus_tag="VQ548_000081"
     CDS             77130..77384
                     /locus_tag="VQ548_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET2653016.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            77431..78204
                     /locus_tag="VQ548_000082"
     CDS             77431..78204
                     /locus_tag="VQ548_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HET2653017.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFTTKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLAKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPASIFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSSQRILLEKQSKKIEELHKMIQDLIEKT"
     gene            complement(78464..79450)
                     /locus_tag="VQ548_000083"
     CDS             complement(78464..79450)
                     /locus_tag="VQ548_000083"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HET2653018.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGLYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            79644..82112
                     /gene="gyrA"
                     /locus_tag="VQ548_000084"
     CDS             79644..82112
                     /gene="gyrA"
                     /locus_tag="VQ548_000084"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003244540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HET2653019.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIALRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEE"
     gene            82112..82855
                     /gene="srtA"
                     /locus_tag="VQ548_000085"
     CDS             82112..82855
                     /gene="srtA"
                     /locus_tag="VQ548_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HET2653020.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
     gene            83099..83896
                     /locus_tag="VQ548_000086"
     CDS             83099..83896
                     /locus_tag="VQ548_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HET2653021.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            84044..84166
                     /locus_tag="VQ548_000087"
     CDS             84044..84166
                     /locus_tag="VQ548_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HET2653022.1"
                     /translation="MTCDFKFETLQLHAGQVVAPATKSRAVPIYQTTSFIFDDT"
     gene            84188..85228
                     /locus_tag="VQ548_000088"
     CDS             84188..85228
                     /locus_tag="VQ548_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HET2653023.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDVDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFAIPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWTASGKFPQFVDEGPSCHNLSYTCDVGAAAFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETSSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKDVGSIFTFHVKGGEEEARKVIDNLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPN"
     gene            85399..86673
                     /locus_tag="VQ548_000089"
     CDS             85399..86673
                     /locus_tag="VQ548_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HET2653024.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKDFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            86683..87561
                     /gene="truB"
                     /locus_tag="VQ548_000090"
     CDS             86683..87561
                     /gene="truB"
                     /locus_tag="VQ548_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HET2653025.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEIILGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALTLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            87829..88104
                     /locus_tag="VQ548_000091"
     CDS             87829..88104
                     /locus_tag="VQ548_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET2653026.1"
                     /translation="MEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQSVMANLSQGL
                     SLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            88212..88850
                     /gene="udk"
                     /locus_tag="VQ548_000092"
     CDS             88212..88850
                     /gene="udk"
                     /locus_tag="VQ548_000092"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HET2653027.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            88978..90318
                     /locus_tag="VQ548_000093"
     CDS             88978..90318
                     /locus_tag="VQ548_000093"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HET2653028.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            90296..90508
                     /locus_tag="VQ548_000094"
     CDS             90296..90508
                     /locus_tag="VQ548_000094"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HET2653029.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            90505..91380
                     /locus_tag="VQ548_000095"
     CDS             90505..91380
                     /locus_tag="VQ548_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HET2653030.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLESLQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            91373..92188
                     /locus_tag="VQ548_000096"
     CDS             91373..92188
                     /locus_tag="VQ548_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HET2653031.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHSVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            92181..92612
                     /locus_tag="VQ548_000097"
     CDS             92181..92612
                     /locus_tag="VQ548_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2653032.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            92619..94286
                     /gene="recN"
                     /locus_tag="VQ548_000098"
     CDS             92619..94286
                     /gene="recN"
                     /locus_tag="VQ548_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HET2653033.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRTIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLDLNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNKMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            94288..95016
                     /locus_tag="VQ548_000099"
     CDS             94288..95016
                     /locus_tag="VQ548_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HET2653034.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQPQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYSRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            95095..96918
                     /gene="lepA"
                     /locus_tag="VQ548_000100"
     CDS             95095..96918
                     /gene="lepA"
                     /locus_tag="VQ548_000100"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HET2653035.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(97120..97200)
                     /locus_tag="VQ548_000101"
                     /pseudo
     CDS             complement(97120..97200)
                     /locus_tag="VQ548_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
BASE COUNT        29744 a        17382 c        21492 g        28866 t
ORIGIN      
        1 tcaagcacaa actccacgta aatccagcaa actcaagccg ctaacagctg aagataaagc
       61 ctgtaaccat gtgctatcta aggagagaag caaggttgag aacatctttg ccaaagtaaa
      121 aacgcttaaa atgttttcaa caacctatcg aaatcatcgt aaacgcttcg gattacggat
      181 gaatttgatt gttggtatta tcaatcatga actaggattc tagttttgca ggaagtctat
      241 tatcaaaaat accatcagga ttatataaga ttgatacagg aaaagtttta ttttatggta
      301 taaatattaa tcaaatagat aaaaaaatat taagtcaaaa tttaggagta gttccacagg
      361 attcattttt attgaaccga agtattcttg ataatataac tttaaagcac gaagttactt
      421 cacaaaagat agaggaagtt tgtaaagcag ttcaaatcta tgatgaaatc atggctatgc
      481 cgatgaaatt taatactatc atctcagaga tggggtcaaa tatttcaggt gggcaaaggc
      541 aacagatagc actggcacgt gcattaataa ataatcctag tattgtaatt ttagatgaag
      601 caactagtgc attagacact attaatgagg aaagaataac aaagtatata caaagtcagg
      661 gttgtactca aataattata gctcatagat tgtcaacgat taaggatgcg gatattattt
      721 ttgtaatgaa aggtggtaag attgttgagt caggaaatca taagtactta ataactcttg
      781 gtggagagta ctacagctta tatacaaaaa ggaaatgagg tgtaaagaaa atgaagaaag
      841 aaaatgaata tgtaatttta acaatagcct cactaggggt gatgattgga atagtgtttg
      901 caattttttt agattttcca gttgaatatg gtatttcttt aggcttgttg aatggaatag
      961 tattgggttc gctgattgtt tacaaaaaca ataagaatta agcataattt tttgctgtaa
     1021 actaaggagt agagatggct atagttgaaa ttataaatct aacaaaaagc tttaaagata
     1081 ttgaagttat tcataacact taaataatag agcaactaca gtagtagctt aaaaacatga
     1141 ttaaatcgct attcttagga gtagcggttt ttctttttgt ttaatactct ttgaaaatct
     1201 cttcaaacca cgtcagcttt gccttgccgt actcaagtac agcctgcggc tcgcttccta
     1261 gtttgctctt tgattttcat tgagtataaa aagggttaag taagtatagt aaattgaaat
     1321 aagatatgaa caaatcgatt agaaaagtca aattaatttc tagaagtatg ttagaaattg
     1381 gtttgaattc cgcaatcaat ttgttcagtt tttatttcat ttcattttat ttaattagat
     1441 tttccaattt tttaattcaa gctaaaaatc cccaatcgta gtgattgagg attgagtaaa
     1501 taaatcttaa acaatacctt gtgcaatcat ggcatttgct acattttcaa aggcagcaat
     1561 gttagctcct gcaaggtagt ctttatcaag accgtatgtt tctgaagtcg ttttagctgt
     1621 gttgaagatg tttgtcatga tgtctttgag acggccatca acttcttcac gagtccatga
     1681 gaggcgaaga ctgttttggc tcatttcaag agctgaaacg gctacaccac cagcgttggc
     1741 agcttttgca ggtccgtaga agataccatt ttctttgtaa actttgatgg catcaaggtc
     1801 gctcggcatg ttggcacctt cagatacaca gataacgcct tgagcaacca aacgtttagc
     1861 tgcttcaccg ttgatttcgt tttgagtggc acatggaaga gcaatgtcat agtttccagc
     1921 gtaagtccat acagtacctt cgtggtaggt tgcagttgct ttttcagctg catactcagt
     1981 caaacgagca cgacgttttt ctttaacatc aaccaaaaga tcgaagtcga taccattttc
     2041 atcgatgaca taaccatttg agtcagaaac agaaataaca gttgcaccga gttcagttgc
     2101 tttttgaaga gcatattgag caacgttacc agaacctgaa ataacgactt tcttaccagc
     2161 aaagctgtta ccgttagctt tgagcatttc ttcagtatag taaaccaaac cgtaaccagt
     2221 tgcttctgga cgaatcaagc taccaccaaa tccaagaggt ttaccagtca agacaccagc
     2281 atcaaattgg ttaagacgtt tgtattgacc gtaaaggtaa ccaatttcac gtccaccaac
     2341 accgatatca ccagcaggta cgtcaagtga tggtccgatg tgtttttgca attcagtcat
     2401 gaagctttgg cagaagcgca tcacttcagc atctgtttta cctttaggat cgaagtctga
     2461 tccaccttta cctccaccga taggaagtcc agtcaagaca tttttaaaga tttgttcaaa
     2521 tccgaggaat ttcaagatcc cttggtttac agttgggtgg aaacgaagtc cacctttgta
     2581 tggtccaaca gctgagttga attgaacacg gtaaccacgg tttacttgaa tttttccatc
     2641 acggtcaacc caaggaacac ggaaagaaac cacgcgctca ggctcagtaa tacgtgccaa
     2701 gatattttct tcgatatact cagggtgttt ttcaaataca ggttctaaag tgttgaaaaa
     2761 ttcttcaaca gcttggagga attcagcctc gtgcccgtta cgagctttca cagtttcaaa
     2821 cacgctttgg atatattctt tagcagatgt catatcgttc tccttttatt gtcatatttt
     2881 attacataag acattatagc agaatttttt ttcactgtaa agaaaaaaca gaaattttct
     2941 aaaaattctt tcaattcagt ttttggtttt tttgaaaata gataaaaaaa cgaacgtttt
     3001 tcttggaaat atctttctca aagacaaaat cttaaagtat ggtatgctat aagaaaagaa
     3061 aatgtttagc aattcagaaa tcacttgtta atttatccgt gatatgttag atttgctagt
     3121 aaaattatga ccattttgga ggaaagcaat atttatacca gactaaaatc aaaaatcatt
     3181 atataatagt gatatgaaat caactaaaga agaaatccaa gccatcaaaa cacttttaaa
     3241 agactctcgt acagctaaat atcataaacg ccttcaaatc gttctatagt aaaatgaaac
     3301 aagaacagga caaatcgatt aggacagtca aatcgatttc taacaatgtt ttagaagtag
     3361 aggtgtacta ttatagattc aatacactat agactgtaat caaacaacga tttggcgaaa
     3421 tgtaaaaaat atgaggagtt cggactcgac tctctccttc aagaaacacg tggtggtcgt
     3481 aaccatgcat atatgacagt tgaggaagag aaagcctttc ttgcccgcca tttgaaggct
     3541 gcagaggcag gagaatttgt tacaattgat gccttatttc aggcttataa aaaggagtgt
     3601 ggatgaacgc ctttttagaa gagctttcac aagcttatcc agatgattat cttttactcg
     3661 ttatggacaa tgctatatgg cataaatcaa gtgccttaaa gattccgact aatattggct
     3721 ttgcatttat tcctccatac acaccagaga tgaacccatt gaacaagtgt ggaaagagat
     3781 tcgtaaacgt ggatttaaga ataaagcctt ttaaactttg gaagatgtca tgaatcaact
     3841 ccaagatgtt atacaaggac tggagaagga ggtgataaag tccatcgtta atcggagatg
     3901 gactagaatg ctttttgaaa gcagatgagt ataagtcctc gttttgaagc cttggaacag
     3961 gccattgcct ccaaagattt ggaaaaagtc cgagaagctt ttaagaaaat gaattccact
     4021 tggaccatca atgaaagtgt ggttcgtgac aatagtacag ctcattatgg acgtgttgaa
     4081 acagctattt ccttcctgcc tagtagcatg gaaaccgaac ctacagatga gtctggaaca
     4141 tgaaaacagc agttgatttc aagaaacaaa aaagaacagt cgaaactgtt cttttatcat
     4201 tatttgagac cgtatttttt gttgaaacga tccacgcgtc catctgcttg agtgaacttt
     4261 tgacgtccag tgtagaatgg gtgtgagtct gatgaaattt ccacacggat caatgggtaa
     4321 gtttcgcctt cgaactcaac tgtttcgtta gagcgttttg ttgaaccgct aaggaattgg
     4381 taaccagtag ttgtgtccat gaagacaact gggcgatatt ctggatggat atcttttttc
     4441 attttgcaat atttcctttc tgccatggtc tctttgcgag ccatagattg ttaccatact
     4501 agtctatcag attctgaaaa gtttggcaag tattttatca gtttttaagc aagtttttta
     4561 acttttggta gatgatttca ttttcttcta ggctatagga attagcacca cttgctagag
     4621 ggtggcctcc accatcatgc tccttggcga tttcattgat aggatggatt ttactgcgta
     4681 agcgaacgcg gtagtggcca tcagcctgtt ccacaaaaat tccccagaga ctaacactat
     4741 caatacgccc aggtgcacct acaatggccg cagtttcagc atcggttaca ttgtattgtt
     4801 tcaagatttt ctgactcagg ataacgcgag cagcaccatt ttcatccact tccagatggt
     4861 cgtagatgta gccttgcagt ttagcaattt tgtagctcat agtgtccatt ttgcgagtga
     4921 gagccgcaaa gtcaaagtta tgttctctca aataagcagc caggcgaaga gtccgtgcag
     4981 tggtagaagg gtagaggaag cgacctgtat caccgacaat tcctgcaaag agcaactcag
     5041 catcgcgatc tgccaaggct agttgggttg tttgggcaaa tagggtaatc atctcgctag
     5101 cgctacttga actagtatcg acccaagaca ggtcaccgta tacatcatca tttggatggt
     5161 ggtcaatctt aatgagaaaa tcaccttgac tatagcgctt atcatcgata cgagcagtat
     5221 tagctgtatc acagacgatg acaagtgcgc cttggtaggc tctatcttca acaagatcca
     5281 tctcagccat ccaagtaaga gttggttcat caaaaccgac ggctttgatg gttttttctg
     5341 ggaaatgatg ttccagcaag gctttcaatc ccacctgact tcccaaggca tcagggtctg
     5401 gtttcatatg acgatgaatg ataatggtgt tgtattcttt aattttttct aaaatttgtt
     5461 ggcaaatctc cataaataac ctcaattctt tctcatttca ttgtagcaca agaattttta
     5521 tttttaaaat gaaaaagatg tgatataatg gagaaagata aattgaggag gacgatatgg
     5581 cattagcaaa aattgtattt gccagtatga ccggtaatac cgaagaaatt gcagatattg
     5641 tagcagacaa attacgtgac ttgggcttgg atgttgatgt tgatgaatgt acaactgttg
     5701 acgcttcaga cttcttggaa gcagacatcg ctatcgttgc gacctatact tatggtgatg
     5761 gtgaattgcc agatgagatg atggacttct acgaagacct agcagatctc aacttgaatg
     5821 gcaaaatcta cggagtggtc ggctcaggag ataccttcta cgatgaattc tgtaaggctg
     5881 ttgatgactt tgaccgtgtc tttgtgtcaa caggagcaga aaaaggttca gagtgtgtta
     5941 aagttgatct ttctgccgag gaagaagata ttgaacgctt ggaacaattc gcagaagaat
     6001 tggctgctaa agtaggataa gcataaaagt gcgctgatgt aatcaatcag tgcatttttc
     6061 ttatcgagag ttgggatttt actagcctaa ttgatggctt tttgatacaa taattcaaat
     6121 aaaggaggag actgtatgga tttagatatt attcgtcaag aaatcgatca aatcgacgac
     6181 caaattgtca aactgttaga agaacgaatg catttagttg agggggtggt tgcttataag
     6241 aaagcttcag gtaaaccgat tttagatact aagagagaag aagttatttt tgaaaaggtt
     6301 aggagtcgtg tagaggacaa gcgctatcag gagactattg tcgcgacttt ttcgtacata
     6361 ctcaaacgtt cgcgtgatta tcaggatcaa aatatcaaat gaaaaaagaa caattttatc
     6421 cgctaggaat ttttctagct gctatgttgg gcggacttgt ccgatatcta gtttccacct
     6481 ggttaccagc cagtccagac tttccttggg gcactctctt tgtcaactat ctgggaattt
     6541 tctgcttgat ttttcttgtc aagggctatc tggtctataa ggggactagt aagggcttga
     6601 ttttagcact ggggacgggt ttttgcggag gtttaacaac tttttccagc ctaatgcttg
     6661 atactgtgaa gctgcttgat acagggcgtt attttagttt agtcctgtat ttgcttttga
     6721 gtatcggtgg aggcctgctt ttagcttact atttggggag gaagaaatgg taatcgtcta
     6781 tcttgcaatc gcctgtggct tgggagcact cgtacggtat ttcttttctc gctataatca
     6841 agcttctaaa ttgccactcg gaacgctcat agctaatctt ttaggttgtt ttttaattgg
     6901 agtattctac aatcatgtag agtctaagga agtatatgct attctagcaa caggattttg
     6961 tggcggttta acaacttttt cgaccttgaa tgacgaactt caaagactgc taagtgataa
     7021 gaaggtcttt tattcttacc tgactttgac ttacataggt ggtttggttg cgattttttt
     7081 aggaattttg ctataaattt ctttactttt ttttagaaat ttggtaaact atatcttgtg
     7141 tgtaatggac gcacaaaaat acagtttatc cgctgaggaa gattcctcaa gattgacaaa
     7201 gataggagaa taaaatgaat ccattaatcc aaagcttgac tgaaggtcaa cttcgtacag
     7261 atatcccatc attccgtcct ggtgacactg ttcgtgtaca tgcgaaagtt gtcgaaggta
     7321 accgtgaacg tatccagatt tttgaaggtg ttgttattgc acgtaaaggt gctggcatct
     7381 ctgaaaacta cacagttcgt aaaatctcta acggtgtagg tgttgagcgt atcttcccaa
     7441 tccacactcc acgtgttgaa aaaatcgaag ttgtacgtta cggtaaagta cgtcgtgcga
     7501 aattgtacta cttgcgtgct cttcaaggta aggcagctcg tatcaaagaa atccgtcgtt
     7561 aattcgacta aaaaactctg ctttttcagc agagttttta tctagctccc ttagttcaat
     7621 ggatataaca actccctcct aaggagtagt tgcaggttcg attcctgcag ggggcatgta
     7681 attagatatc aaagaagttt gtcaaagagt ctttgatatt aaaagaacgc ataatatagg
     7741 ggattgtctc cataatatta tgcgttttat tattgaaaaa tttgggcaat catcagataa
     7801 aattgagact atatcgagta tataaatgtt tgtatagtca atttattcaa aatcgtcaag
     7861 ttctaaatta tttaaaggac tataacattc atatttcttt aagtaattgt ttatttcttc
     7921 agcagtggaa cgaggtaaat taactcttaa atagtcaata tcttccttag ataaaaaatg
     7981 atttgcattc aaaattgaga agcgaaataa tgcttcatca aaagcaaaat cataatcgtc
     8041 atcagataat gattccatta atgtttgaat atgttttagt gagtagtcag gtatcgaatc
     8101 gggataatat actggataat cagtggctga aaaattgttt tctaatcctg aaatagtaat
     8161 tatcaaagat tctatgtaat atattaaagc atgtttaata ttaccttctt gttccaaatg
     8221 tcttccctga gcctttcgtg tgttagataa gcatccaaaa tctcctgata cagtattcct
     8281 atgagcttgt ttatttaaga gactccattt tatatcacca aaagttgctt taaaagagat
     8341 attgtttttt tctttacaat aatcttccat acttatgtct ttatcatagt atgctttgat
     8401 atagtcacta tgttcgataa taagattttg tgcttctttt gttagtttaa attcgaacgg
     8461 aatatctaaa ttgtcaatgt taacattatt aattattctt gtaattaatt ctgctttttt
     8521 tccagaagta gctaaattat gtttagataa tatagttttt aattctacta ctgtaagata
     8581 tgataaagtc ttatttttag tgaagtatcc taatttgtat aattgattgt gtgtagattc
     8641 agggtcaatt tgaagagagt atttaaaata tcttgggaaa ttataatttc tccctgtttt
     8701 ttgagtccaa tctatgagta tgagttgccc aggagtaagg ccacattcta attcgtttag
     8761 gtaaaaattg ttacaatcag aatttgtgtc tctattatga ttattttgtt ttaaattaaa
     8821 tagtttgcta aaaaaattca ttggatttta ttgctaatca attcttattg aaaaatgata
     8881 cttttacagt acccatgttc ggatggcatg ggcaacgccg gattcgtcat ttgttttggt
     8941 gatgtatttg gcgatttttt tgatttctgg atttccattt tccatgacaa cggggtttcc
     9001 aacgacttcc agcatgggac ggtcattttc ttcatcaccg attgccatgg tttcatcttt
     9061 ggtcaatccg agtttttcag ccaagtgagt aatggctgaa cccttgtcta cattcttttt
     9121 aaggagttcg aggtagaaag gagcagattt gttgatggag tagcgctcgt aaaattctgc
     9181 tggaattttt tcaatcgcag catcgagaat ttctggttca tcgataaaca tacatttaac
     9241 aatttctttg ccagccattt cttcaggggt acggtagaag ataggcatgc tgacgagggt
     9301 tgattcgtgt acagtgtatt ttccgatatt gcgatttgca gtatagatac cgtccttggt
     9361 aatggcatgc atgtggacac cgagcttgcg actgaggaat tccatatcca gataatcctc
     9421 ataggtcaag gattcgctga taatctcatg gccagtagca gtttcttgga caagggcacc
     9481 attgaaggtc accacatagt caccttggtc tctcaactgc aagtcgtcca gaagtttggc
     9541 aacacctgcg atggggcggc cagttgcaat cacgactttg acaccagctt ctttggcatc
     9601 ttggatggca gaaaagactt caggagtgat ttccttttgg ctgttgacta gggttccgtc
     9661 aatatcgacg gcaattagtt taatactcat aaaattcctc ttctagtttt tatttggggt
     9721 aaaatgatcg ttctcaatca agtgtaaaaa ttgctgggta atgcttgcga agatgctgtt
     9781 ttggtctaac atttctttag ggaaatagaa acgattatct ccgtggcgac tgccagcaag
     9841 ggattggacg ataggagaca ggctagagag ttcggccagt tctccatttt tttgtaaaat
     9901 ctcaatctgt gtccgtggat tttgagattc gggacgatag atatcataag ggaggtcaaa
     9961 gttcttatga atggcagtat agtagtcggg atcaaagccg atgtcctcaa ccaattttct
    10021 catgctagta agttgatctt ggtcctcttg tgaaaaggta atggatttaa agaccttgcg
    10081 gttgacaaag cgttgagata aatctgcaag aattttgtca ggactagtca tccaaagctg
    10141 gaagtaggta ttcatcacgc catcatccag agccagatag tcagtcaagg tcacattttt
    10201 ttcgaagaaa ggcaggagat gtggggaagt tcgtgcaaag aaattcttgt cctcagggta
    10261 gagttccttg gcgcgcttga gaagattctg taggagaact tccatggcgc gtgttgctgg
    10321 gtggaaataa acctgcatgt acatctggta gcgactgagg acgtagtctt cgatggcgtg
    10381 catgccattg cgctgaaagg cgataccatt ttcgacagga cgaatgactc ggaggatgcg
    10441 agtcaggtca aattccccat aggatgctcc tgtaaaatag gagtcgcgca agagatagtc
    10501 catgcgatct gcgtcaatct gactagaaat gagctgcacg acctgcttat taggataggt
    10561 atggtcaatg acactggcca ccttttctgg gaaatcaggt gccacttgta gcaggacttg
    10621 gtgaatctct gtctcaggat tttgaataat ctcctgagta atggcttcat ggtctgtatc
    10681 aaagagattt tcaaaagtat gggagtaggc accatgccca aggtcgtgta ggagagcagc
    10741 ggtcacggtc aagagagact cggcaggatt ccattcctca ggatattttt cttcgaaaat
    10801 ctctgtgatg cgtcgtgcaa tttcatagac tcctagacag tgagagaagc gactgtgttc
    10861 tccaccgtgg aaggtataac tggaagttcc cagttgtttg atccggcgca aacgctgaaa
    10921 ttcttttgta ttaatcaagt catagatgat ttgattattg acatggatgt agttgtgaac
    10981 tgggtcacgg aatacttttt cgttcatatg accattatag caaaatcctg ctctttttgg
    11041 taaaatagta ggacaagaga caagaaagag ggcctgatgt gaagattcgg atgcgaaata
    11101 caattcagtt tgatgagcag ttggaagtga ttgaccagct ttatgatgtg gaagtgcatg
    11161 aaaaaggaga ttatagctac ctgcttttct ataatgagga aaaggaaaaa gtagtgatta
    11221 aatttcatgg tcaagaactt atgatgagcc gattttctaa tcccaagacc attatgcgct
    11281 ttctaaagga tagcgatagt ttagcctata ttcctacacc tatgggcatg caggagttta
    11341 tcatccaaac gagccattat caagttgata ggcaaaagat tgaactagat tatcaactac
    11401 aaaatcaaga gggacatcct tttgccagct atcaattgga aattacttgg ggctaggctc
    11461 atgtcttttt caaatttagc tatctatctt cttggatcgg cttcctagtg tggtagatta
    11521 ggctaatttt tggtataata aaagttatgg aaatcgaaaa aaccaatcgt atgaatgcgc
    11581 tctttgaatt ttatgcggcg cttttgacag ataagcaaat gaattatatc gagctctact
    11641 acgctgatga ttacagcctt gctgaaattg ccgaggagtt tggtgtcagt cgtcaggctg
    11701 tctatgacaa tatcaagcga acagaaaaga ttctggaaga ttatgagatg aaattgcaca
    11761 tgtactcgga ctatattgtc cgcagtcaga tttttgatca gattttggag cgctatccca
    11821 aggatgactt tctgcaggag cagatagaaa ttttaacaag cattgataat agagaataag
    11881 aggaagaaaa atggcatttg aaagtttaac agaacgtttg cagaacgtct ttaaaaatct
    11941 acgtaaaaaa ggaaaaatct ctgaatctga tgtccaagag gcaaccaaag aaattcgctt
    12001 ggccttgctc gaggccgacg ttgccttgcc tgttgtaaag gactttatca agaaagttcg
    12061 tgagcgtgca gtcgggcatg aggtcattga tacacttaat cctgcgcaac agattattaa
    12121 aatcgttgat gaggaactga cagccgtttt aggttctgat acggcagaaa ttatcaagtc
    12181 acctaagatt ccaaccatca tcatgatggt tggtttacaa ggggctggta aaacaacctt
    12241 tgctggtaaa ttggccaaca aactcaagaa agaagaaaat gctcgtcctt tgatgattgc
    12301 ggcggatatt tatcgtccag ctgccattga ccagcttaag accttgggac aacagattga
    12361 tgtgcctgtc tttgcacttg gaacagaagt accagctgtt gagattgtac gtcaaggttt
    12421 ggagcaagcc caaactaatc ataacgacta tgtcttgatt gatactgcgg gtcgtttgca
    12481 gattgatgag ctcctcatga atgagcttcg tgatgtgaaa gcattggctc aaccaaatga
    12541 aatcttgctt gtcgttgatg ctatgattgg tcaggaagca gccaatgttg cgcgtgagtt
    12601 taatgctcag ttggaagtga ctggggtcat ccttaccaag attgatggcg atactcgtgg
    12661 tggtgctgct ctgtctgttc gtcacattac tggaaaacca atcaagttca ctggtacagg
    12721 tgaaaagatt acggacattg aaaccttcca cccagaccgc atgtctagcc gtatccttgg
    12781 tatgggggat atgctcactt tgattgagaa agcttctcag gaatacgatg aacaaaaagc
    12841 ccttgaaatg gctgagaaga tgcgcgaaaa cacctttgat tttaatgatt tcatcgatca
    12901 attagatcag gtgcaaaata tggggccgat ggaagacttg ctcaagatga ttccaggtat
    12961 ggccaacaat ccagcccttc aaaacatgaa ggtggatgaa cgccagattg ctcgtaaacg
    13021 tgccattgtg tcttcgatga cacctgaaga gcgtgaaaac ccagatttgt taaatccaag
    13081 ccgtcgccgt cgtattgctg ctggttctgg aaatacattc gtcgaagtca ataaattcat
    13141 caaggacttt aaccaggcta aacagctcat gcagggtgtt atgtctgggg atatgaataa
    13201 aatgatgaag caaatgggga ttaatccaaa taaccttcct aaaaatatgc caaatatggg
    13261 aggaatggat atgtctgccc ttgaaggaat gatgggacaa ggcggtatgc ctgacttatc
    13321 agctctcgga ggagcaggaa tgccagatat gagccagatg tttggtggcg gtttgaaagg
    13381 taaaattggt gaatttgcca tgaaacagtc catgaaacgt atggctaaca aaatgaagaa
    13441 agcgaagaag aaacgcaagt aagacaagag attgatgcaa atctcatttg atgagaaaat
    13501 aaagtaaaaa tttctatgat aaaacgtaca gtatcaaggt tttagaatat ctgatattat
    13561 acgttttttg attttaataa ttttgttaag acacttttat tatggtatac gaaaaatcca
    13621 ctcagctgtc tgagtggatt aggtgtattt agactcttag tctttatttt cgtatggcaa
    13681 gatcaagttc aagatgattc ctgtcatggc tgaaagggca gtacctgaaa gtgtaactgg
    13741 accaagttta aggatagctc ctccaagtcc aagaaccaac atagcacttg cgatgatgag
    13801 gtttcgcatt tgagcgaaat caacacgttc tttaatcaag actttcaaac cattgctggc
    13861 gataacccca tagagaagga ttgacatacc accaagtaca gcgtttggaa tagttgaaat
    13921 caaggcagtg aatttaccaa ggaagctgag ggcaatcgcg atgaaggcag cgttacggat
    13981 aactgagaca gaagcgatac gagtcatacc gataacccct gtattttctc cgtaagttgt
    14041 attggctggt ccaccaagga aggcagaaac agaagttgcg ataccgtcac caagaagagt
    14101 acggtgaaga cctggttctt ttaagaattg acgaccacag atttgaccca aaacagtatg
    14161 gtctccgata tgttcagaaa ttgttacgat agcgattggc aagatagcga tggcttctgg
    14221 accaaagtaa agattgtact ctttaaaggc accacctgtg ctaaatggca agtagaaacc
    14281 aggaatttcg aaccagttgg ctttaagaac tggtgtaaag tcaaccaagc caagagttag
    14341 tgcgaaaagg taaccaccga taatggcaaa gaggaatgga atgattcgta ggaagccttt
    14401 tccttttgta ttgataaagg cagcaattag gaaagtaaca acggctacca gagcattttt
    14461 ccaatttccg tctgctacaa gacctgcatt ggtaacagct gaacctgcaa gtccaagacc
    14521 gataacgatg atcataggac cgataatgat tggtggcaag agtttatcaa tccattttgt
    14581 tcctacaaat cggatgctgg tagcaacaag gacatagacc aaaccagtca agataacccc
    14641 tgtttgggca gcagatacat ccccccccat ttctttcata gccagtgaca tagctgtgat
    14701 aaaggcaaat gaagaaccta gataaactgg aactttaaaa ccagtagcaa tcatgtagat
    14761 gagtgttcca acacctgaag caaaaagggc aacagataca ggcattccca aaatcaatgg
    14821 taccaagatg gtcgcaccaa acatggcgaa aacgtgttgg aaactaagga gaattccttt
    14881 tccagccgaa ggacgttggt caacgtctag taacaaatca acagttgatt cttgtttcat
    14941 ataaacctca cttttgggca tcaaaaaaga gcccattatt ttacagcaat aggccctcag
    15001 agtaagactt ctttaaaatt tagattttaa agagttttaa atatttctgc gtcttcgtca
    15061 cctcacggga tgacattaaa aacctttgct taggatagta tagcagaaaa aaatgatttt
    15121 gtaaatcatt ttttcccgag cctagaaata aaagagcgag gctgattttg taaatcattt
    15181 tttcccgagc ctagaaataa aagagcgagg ctgattttgt aaacatttgt ttactaaaaa
    15241 atttaaagtg ggcgtttatt tggcatacca gccttacgcg gatatttatt tggtgtttct
    15301 tttttctttt ctaccactgt gatatagcgc ggatctctat tcggtagggc gtagctgaga
    15361 ttgtcttcga ccttactaaa aaggagattg agggcattct tagcttctaa taattcctca
    15421 ggcgcattgc tggccttgag tgccaatagt tttccaccaa ccttaaggta gggaatggtc
    15481 aattcagata ggacctgcat acgggcaacc gcacgagctg ttacaaaatc atattgagca
    15541 cggaagttct tgtcttgggc aaaatcttcg gcacgtccgt ggtagaaatg aactccgttc
    15601 aaatccagtt cttgagccaa gagttgtagg aagttgatgc gcttattgag tgaatcaata
    15661 atggtcacat ctaactccgg atagagaatt ttcattggta gactaggaaa tcctgcccca
    15721 gccccgatat caagaagttt gatagtttca ttgggaatca aaccttgaag aatgggtgca
    15781 atcgaatcgt aaaaatgttt gagataaact tcttccttgt ccgtaatcgc cgtcaaatta
    15841 atcttctcat tccactcgac caagagctca aaataacgtt caaattgttc tttttgctgg
    15901 tccgaaagtg gaagattctg ctcggcaagc aagttgtaaa atgtttttgg tttcatagtt
    15961 atttccttct ttagtatcat cttattttac cacaatcata gaaaatttga tatactggta
    16021 ctaatctaaa agcagaaagg acttatatta tgacttggat tattcttgga gttatcgctc
    16081 ttattgttat ttttgtgatt gttagctata acggtttggt taaaaatcgt atgcaaacca
    16141 aggaggcttg gagtcagatt gatgttcagt tgaaacgtcg aaatgacctc ttgccaaact
    16201 tgattgagac tgtaaaaggt tatgccaaat atgaaggttc tacccttgaa aaggtggcag
    16261 aactacgtaa ccaagtggcg gcagcgactt caccagcaga agctatgaaa gccagtgatg
    16321 ccctcactcg tcaggtttca ggtatttttg cagttgcaga aagctatcca gatttgaaag
    16381 ctagtgctaa ctttgttaaa ttgcaagagg agttgacaaa cacagaaaat aaaatttctt
    16441 actctcgtca actctataac agtgttgtca gcaactacaa tgtaaaatta gaaactttcc
    16501 cgagcaatat tatcgctgga atgtttggat ttaaagcggc agatttcctt caaacatctg
    16561 aagaggaaaa gtcggttcct aaagttgatt ttagcggttt aggtgactaa gatgttgttt
    16621 gatcaaattg caagcaataa acgaaaaacc tggattttgt tgctggtatt tttcctactc
    16681 ttagctcttg ttggttatgc ggttggttat ctctttataa gatctggact tggtggtttg
    16741 gttatcgcac tgattatcgg ctttatctac gctttgtcta tgatttttca atcgacagag
    16801 attgtcatgt ccatgaatgg agcgcgtgag gtggatgagc aaacggcacc agacctctac
    16861 catgtagtgg aagatatggc tctggtcgct cagattccta tgccccgtgt tttcatcatt
    16921 gatgatccag ccttaaatgc ctttgcgaca ggttctaatc ctcaaaatgc ggctgttgct
    16981 gcgacttcag gtctactagc tatcatgaat cgtgaagaac tagaagctgt tatgggacat
    17041 gaagtcagtc atattcgtaa ttatgatatc cgtatttcga ctattgcagt tgcccttgct
    17101 agtgctatca ccatgctttc tagtatggca ggtcgtatga tgtggtgggg tggagcaggt
    17161 cgcagacgaa gtgatgatga ccgagatgga aatggtcttg aaatcattat gctagtggtt
    17221 tccctactag ctattgtact ggcacctctc gctgcaacct tggttcagct cgctatttct
    17281 cgtcagaggg aatttctggc agatgcatct agtgtcgagc tgactcgcaa tccccaggga
    17341 atgattaatg ccctagataa gttggacaat agcaaaccta tgagtcgcca cgtcgatgat
    17401 gctagcagtg ccctttatat caatgatcct aagaaaggtg gggggttcca aaaactcttt
    17461 tatacccacc cacctatctc agaacggatt gaacgtttaa aacagatgta aaagaatcca
    17521 gaggtcgtct ctggattttt gctatgttgc aaatttataa atcttctaaa ttaactagct
    17581 tcaaaccgtg ttctgtcatg cgatagatga tcgagcagac ttcttttaag aaacgacggt
    17641 catgcgaaac agtgatgaga ccgcctggat aggttgcaaa gagttttctg atttggggtt
    17701 gagaagtggg agaaaagttt cgtgtgggtt catccagcag gagaaagttt ggtttgcgca
    17761 gaactagatc caaaagcagg agttttccct gttgtccgcc agataaggag cgaatttgat
    17821 gctgcatttc tggataactg aaattgagac tggctaggtg agattggatt ttctgaagtt
    17881 cctctttttc cccagttttg ctgatataag ctattgagga taaatccaat tgcagttttt
    17941 tgtggtaatc ttgtggcata aaaccaagtg aaatctctct tttatcattc agaagttgct
    18001 gtaatttggc taacagagtt gatttcccaa caccatttgg gccgatgata ccgatttttt
    18061 cttggccacg gacagttagt tgcagttcct gagccaaaac acggtcgtca atggacaaat
    18121 tttctttttc cagttggact aagactttag aagctggtaa tggttggatg tctgaaaaga
    18181 aaagttggat ttgttcctct tcaagtggct tttgagtcat ggactgagct gtcttttcgt
    18241 agcgtttttc ttgtgagagg acagttttca tctttttagc caataggcga ccggcagtac
    18301 tatctttggt agctcgaagc gcagtttcta cattttgctt aactctccga tgtttttcca
    18361 tggttttatc gtaggctctt tggttgttag cagcttgctg actttgtttg gcaaaattag
    18421 cctttctctg ctcactatag ctatcatagt ctaaatgctc tactagcgtt tccgcttctt
    18481 tacggtgttt gaccagtcgc aagtgaacaa tagtgtctgc cgtttcagaa agaaagtctt
    18541 catcatggga aatgaaaata acggtttgcc tggtcttttg aatctggcct tttagccaat
    18601 caactgtctc aaggtctagg tcatttgaag gttcatctaa aaatagaatc tcaaagggtt
    18661 tggctaactc atggataagc tgaattttca aagcttcgcc ccctgataga ttgccaatct
    18721 cttggtcact tgcgaaacga ttgctatcaa aatgcaattc ctccgccaaa cgatagagga
    18781 tactgtagtc taaatcaata gaatctaaaa agaagtagtc gtgtaaagtt ttctttttta
    18841 ggtcctcagg gactttttga ggaatgtagg ccagtgactg ataatcagac tggatgtctc
    18901 ccttgatagt gaaatcagac aaatcttccc ccattaaagt tttaagtaag gttgatttac
    18961 catttccttc ttcgccaata atagctacct tttccccgtc ttgtatggtc atgcttaggt
    19021 cagagacaag gtctcgtaaa tctttgtttt gtgtgatggt caggtgattg atttttatca
    19081 tactattgcc ctttctagaa tgtcgatagt gcataacaaa aagctctact ttacctagta
    19141 gagcccaaag tctatgtcaa aaaaactcta ttaacatgcc agaaaaagag cataaaagag
    19201 cacacaaaaa gagacaaaaa caagatctac taaataaagg ttctttattt gatagactta
    19261 gttgttcatg tctcccttac ctccgagtat tagtatcttt atactatact tttaaggaaa
    19321 ttttgtcaac agaaaactgg aaattctatg ctctaaaatc caaaaacagg tccatagaga
    19381 cttagtacgt gtttgacatg ctcgtaatgg attttatcat agtttcgcca agcagtgcgt
    19441 gcttgatcgt ttagttttag gctacccagt ccaatcagag gactggtggg ttggtaaaat
    19501 ttctcaagat caattaagat actgttgttc aacttttccg tttttttgag ctcttgcata
    19561 gtagtgttta gcagctcttg tagtcgaata tcatctgccg taccctgttt acagttttgg
    19621 tagcttttat ttaacttgga taggagttga atgagtttct tgtcttccat gtcttccata
    19681 tgagcatcct ccttgatctg atgtactctt tccctatagt atagcactaa aaaataaaac
    19741 tgtcatagta aatatgttaa aattttgaat tttaattaca aagtttggtg tgctgatttg
    19801 tagccttttc atggtataat caagagagta aatctttatg gaggaagtat gaaattaaat
    19861 attcaagaaa ttcgtaagca gtctgaaggt ttgaactttg aacaaacgtt agatttagtt
    19921 gatgacctgc gtgcacgtaa tcaagaaatt ttagatgtaa aagatatcct tgcagttggg
    19981 aaagtacaat atgaagaccg tatgtatttc ttagattatc aactatctta taccattgtt
    20041 cttgcttcga gtcgcagtat ggagccagtt gagttagttg aatcttatcc agtcacggaa
    20101 gttttcatgg aaggcgcaac taaccagcta gatcaagaag ttttagatga tgacttggtc
    20161 ttgcccattg aaaatgggga gcttgacctt gctgagagtg tatcagacaa tatcctgcta
    20221 aacattccta tcaaggtctt gacggctgaa gaagaagctg gtcaaggatt tatctcagga
    20281 aatgactggc aaatcatgac agaggaagaa taccaagctc aacaagcagt aaagaaagaa
    20341 gaaaacagtc cttttgctgg cttacaagga ctatttgacg gagatgaata atggtcttgt
    20401 caaaaaaacg agcacgaaag gtgctagaag aaatcattgc cctcttccca gatgccaagc
    20461 ctagtcttga ttttaccaat cattttgaac tcctggttgc ggtcatgtta tcagcccaga
    20521 cgacagatgc agcggtaaat aaggccacac caggtctctt tgttgccttt ccaacacccc
    20581 aagctatgtc tgtagcgaca gagagtgaga ttgcttcaca tatttctcgc ttgggattgt
    20641 atcggaataa agctaaattc cttaaaaaat gtgcccaaca gttactagac gattttgatg
    20701 gtcaagtccc tcagacacgt gaagaattgg agagtttggc aggtgttggt cgcaagacag
    20761 ccaatgttgt catgagtgta ggatttggga ttccagcctt tgcagtggat actcatgtgg
    20821 agcgtatttg caaacaccac gatattgtca aaaaatcagc gacgccactt gaggtggaaa
    20881 agcgggtcat ggatatcttg ccgcctgagc agtggttagc tgcccatcag gccatgattt
    20941 attttggaag agccatttgc catccaaaaa atccagagtg tgaccagtac ccacaattat
    21001 atgattttag caatttgtaa gatgctacat tgaaactttt tgcttgattt taagcatgct
    21061 ttgtgctata gtaaatgata actaaatatt cctttaaacc tgtcccgtga ggcaggcaag
    21121 gagcgcgata aagtagaagg gtgaagtcta tactgtttgc agtagggctc gcttggctat
    21181 aaatttcaag tctccttgtt taaggagact tttctttttg gaggtttgtc atgaaaacaa
    21241 aagaagttgt agacgaattg accgtcaaac gagcgattac gcgtattact tatgagatta
    21301 tcgaacgcaa caaagatttg aataagatcg tcttggctgg tattaaaact cgtggtgtct
    21361 ttattgccca ccgaatccaa gaacgtttga agcagttaga aaatctttca gttcctgttg
    21421 tggaattgga tactaaacct ttccgtgatg atgttaaaag tggagaagat acttctttgg
    21481 tttctgtcga tgtgacagac cgcgaagtta tcttggtgga tgatgtgctc tatacaggtc
    21541 gtaccatccg tgctgctatt gataatattg tcggtcatgg tcgtcctgcg cgtgtgagtt
    21601 tagcagttct agtcgatcgt ggacatagag aattgccaat ccgtccagat tacgttggaa
    21661 aaaatatccc aaccagtcgt tctgaagaaa tcatcgtaga gatgacagaa cttgatgacc
    21721 aagacagagt tctgattact gaagaagctt agaaagttaa aggagtagcc atgtcagaaa
    21781 atcaacaagc attgaaccat gtggtgtcca tggaagacct cactgtcgat caagtaatga
    21841 aattgatcaa gcgaggaatt gagtttaaaa atggagccca gcttccctat gaagaccatc
    21901 cgattgtttc caatctcttc tttgaggatt ctacacggac acataagtcc tttgaagtcg
    21961 cagagattaa acttggattg gaacgacttg actttgatgt gaagactagt tcggttaata
    22021 agggtgagac actttatgac accattttga ctctgtctgc tttaggagtg gatgtctgtg
    22081 tgattcgcca tccagaggtc gactactata gagaattgat tgctagtcca acgattacga
    22141 cttccatcat caatggtgga gatggttcgg gccaacaccc tagccagagc ttgcttgatt
    22201 tgatgaccat ttatgaggaa tttggccact ttgagggtct taaagttgct attgcaggtg
    22261 acttggacca ctcacgcgtt gccaaatcca atatgcagat tttgaaacgc ttgggagctg
    22321 aactcttttt cgctggacct gaggaatgga gaagtcaaga gtttgcagac tatggaaagt
    22381 ttgtaaccat tgatgaaatc attgatcagg ttgatgtcat gatgtttctc cgtgtgcaac
    22441 acgaacgcca tgatagtgga gctgtatttt caaaagaaga ctatcatgcc caacatggct
    22501 tgactcaaga acgttacgat cgtttgaaag aaacagcaat cctcatgcac ccagctccaa
    22561 tcaatcgtga tgtagaaata gcagaccact tggttgaagc accaaaatca cggattgtcc
    22621 aacaaatgac caatggtgtc tttgttcgaa tggcaatctt agaatccgta ctagcgagta
    22681 gaaacgccaa ctaaaacaca agacgttaaa agacgccagt gagcgtccac gagaggtgaa
    22741 aatatgacaa aaagaattct agtattagaa gatggcacag tttttgaagg caaggccttc
    22801 ggagcagata ttgatgtaac aggcgaaatc gtctttaata cagggatgac cggctaccaa
    22861 gaatccatta cagaccagtc ttataatgga caaatcttga cctttactta tcctttggta
    22921 ggaaattatg gtattaatcg tgatgattat gaatccatta ttccaacttg taagggagtc
    22981 gttgtttttg aagaagcgcg tagagctagc aactggcgca accaaatgac cttggatgaa
    23041 tttttgaaag ccaagaaaat tccagggatt tcaggaattg atacgcgtgc tcttaccaag
    23101 attatccgta agcatggtac tatgcgtgca accttgaccc atgttgggga cagtatggac
    23161 catgtgacgg accagctcca agcaacagtt ttaccgacag acaatatcaa acaggtttct
    23221 actaaaacgt cttatccagc tccaggagtt ggtttgagcg tggtgctagt ggactttggt
    23281 ctcaagcact caatcctacg tgaactttct aaacgcaact gtaacgtgac agttgttcct
    23341 tattcgacaa cggctgaaga aattctccat ctcaatcctg atggagttat gttgtcaaat
    23401 ggtccaggta acccagaaga cgttccacaa gcactcgaca tgattcgcgg tgtacaagga
    23461 aaaattccaa tctttggtat ttgtatggga caccaactct ttgcaatggc aaacggggct
    23521 aagacctata agatgaagtt tggccaccgt ggattcaacc atgcggtacg tgaaatcgca
    23581 acaggacgag tagacttcac cagccagaac catggttatg cagtcagccg cgaggatttg
    23641 ccagagcact tgattattac ccacgaagaa atcaatgaca agtcagtgga aggtgtgcgc
    23701 cacagatacc aacctgcttt ctctgttcaa taccacccag atgcagctcc tgggccacac
    23761 gacgctagct acctatttga cgagtttatc gagatgatgg aagtttttaa acaatcaaac
    23821 taagaatgag taaaagctcg tcggagaatt tatgtaactg aacatggacg gaaagctcag
    23881 aatttagaga aaccaacttg gattgtcaat ccttccttga tttcctaaaa ttcaatcgct
    23941 ttctagtcgt cctttgtatc ttatttaatg tcgccctgag aggcgacgaa tagaaaggag
    24001 aagatacatt gttcgcggaa gtgaacacgc cctaagaact gtgtgaaaaa gataaacatc
    24061 gtcttgacgc tgaaggcgtc tgcgccgagt ttcctatttt cactgtgttc tttacgggct
    24121 ttgtatcata aactatgcct aaacgtactg atattcaaaa aattatggtg attggttctg
    24181 gtccgattat tattggtcag gctgctgagt ttgactacgc tgggactcag gcttgcttgt
    24241 cgttgaaaga ggaaggttat gaggttgttt tggttaactc aaatcctgca accatcatga
    24301 cggacaagga aattgctgac aaggtttaca ttgaaccgat tacacttgag tttgtgacac
    24361 gtattcttcg taaggaacgt ccagatgcct tgctaccaac actcggtggt cagacaggtc
    24421 tcaacatggc catggaattg tctaaaaatg gtatcttaga tgagcttggc gttgaacttc
    24481 tgggtaccaa attatctgcc attgaccaag cggaggaccg tgacctcttt aaacaattga
    24541 tggaagagct tgaacaaccc attccagaat ctgaaattgt taacacagta gaagaagcag
    24601 ttgcctttgc agcgacaatt ggctacccag tcatcgttcg tccagccttt accctcggtg
    24661 gtactggtgg tggtatgtgt gccaacgaga aagaattgcg tgaaatcact gaaaatggtt
    24721 tgaaattgtc acctgttacc caatgtttga ttgagcgttc gattgccggt ttcaaggaaa
    24781 ttgaatacga agtgatgcgt gactcagctg acaatgcctt ggttgtttgt aacatggaaa
    24841 actttgaccc agttgggatt cacacggggg attccattgt atttgcccct gcgcaaacca
    24901 tgtcagacta tgaaaaccaa atgcttcgtg atgcgagctt gagcattatt cgtgccctca
    24961 agattgaagg tggatgtaat gttcagctag ctcttgatcc taacagcttc aagtattatg
    25021 ttatcgaagt aaaccctcgt gtatcacgtt cgtcagccct tgcttctaaa gcgacaggat
    25081 atccgattgc taagttggct gccaagattg cagtaggttt gaccttggat gaggttataa
    25141 acccagttac aggttcaacc tatgccatgt ttgaaccagc ccttgactac gtagttgcta
    25201 agattccacg tttcccattt gacaagtttg aaaagggtga acgccgtctc ggtacacaaa
    25261 tgaaggcgac tggagaagtc atggcaatcg gtcgtaacat cgaggaatct cttctcaagg
    25321 cctgccgctc ccttgaaatt ggggtgcacc acaatgaaat acctgaactt gcagcagttt
    25381 ctgatgatgc cttgattgaa aaggttgtca aagcccaaga tgaccgtctc ttctacgtat
    25441 cagaagcaat tcgtcgtggc tacacacctg aagaaattgc agagcttaca aaaattgata
    25501 tcttctatct tgataaactc ttgcatatct ttgaaattga gcaagaattg ggtgctcatc
    25561 cacaagatct agaagttttg aaaacagcca aacttaatgg tttttcagac cgtaagattg
    25621 ctgaactctg gggaacgact gatgatcaag ttcgccaact tcgcttggaa aacaagattg
    25681 ttccagttta taagatggta gacacttgtg cggcagagtt cgactccgaa acgccatatt
    25741 tctattcaac ctatggttgg gaaaatgaat ctatcagatc tgataaagaa tctgtacttg
    25801 tcctaggttc aggtccaatc cgtattggtc aaggggttga gtttgactac gcaaccgttc
    25861 actctgttaa ggctatccag gcagctggtt atgaagctat catcatgaac tcaaacccag
    25921 agaccgtttc aacagacttc tctgtatcag ataagcttta ctttgagcca ttgacattcg
    25981 aagatgttat gaacgtcatt gacttggaac aaccaaaggg agttatcgtt cagttcggtg
    26041 gtcaaacagc catcaacctt gcggagccat tggcaaaagc aggtgtgacc atccttggta
    26101 cacaggttgc tgacctagat cgtgccgaag accgtgacct cttcgagcaa gctctcaaag
    26161 aattggatat tccacagcca ccaggacaaa cagctaccaa tgaagaagaa gcagctcttg
    26221 cagctcgcaa gattggcttc ccagttcttg tccgcccatc ttatgtactt ggtggacgtg
    26281 ccatggaaat cgttgaaaac gaagaagacc ttcgttctta catgcgaact gctgttaagg
    26341 ctagtccaga ccacccagtt cttgtcgact cttatatcgt tgggcaagag tgcgaagttg
    26401 atgccatttc agatggtaaa aatgtactca ttcctggtat catggagcat atcgaacgtg
    26461 ctggtgtcca ctcaggtgac tcaatggctg tttacccacc acaaaccttg tcgcaaaagg
    26521 ttcaggagac catcgcagac tacaccaaac gcttagcaat cggtcttcac tgccttggaa
    26581 tgatgaacat ccagtttgtt atcaaggatg aaaaagtcta cgttattgag gtcaatccac
    26641 gtgccagccg tactgttcca ttcctatcta aggtaaccaa tattcctatg gctcaagtag
    26701 cgaccaaact cattcttggt caaagtttat cagaacttgg ctaccaaaat ggactttacc
    26761 ctgaaagcac ccgtgttcat atcaaggcac ctgtcttctc ctttaccaaa ctagctaagg
    26821 tagacagctt gctcggtcct gaaatgaagt caacaggtga agttatgggt tctgatgcta
    26881 ctttggaaaa agctctctat aaagcctttg aagcttctta tctacacttg ccaacttttg
    26941 gtaatgtcgt ctttaccatc gctgatgatg ccaaagaaga agccttgaac ttggctcgtc
    27001 gtttccaaaa cattggttat ggaatccttg cgacagaagg gacagcagcc ttctttgcta
    27061 gccatggctt gcaagcccaa cctgttggta agattggtga tgacgataag gatatcccaa
    27121 gttttgtacg caaaggaaga attcaagcta tcattaacac agtaggaaca aaacgaactg
    27181 ctgacgaaga tggtgagcaa attcgtcgtt cagccattga acacggggtg cccctcttca
    27241 cagcgctaga tacagctaat gccatgctta aggtacttga aagtcgtagc tttgttacag
    27301 aagcgattta aatagaaaaa taagatatag cagactgaat ttagaacagt acacaggaat
    27361 actaaaatat ttctagaaat taatttgaat tttctaattg atttgttcgc atcttatttc
    27421 aatctactat agaaaaaagt ctttaaaatt ataaaacgca tcatatcaag gtttttcaaa
    27481 aaccttgata tgatgcgttt tattgtggga atatgtattt cattttctac taaaattatg
    27541 tttttgaata acctctatct tagtagtttg tataatcccc ctcaatcagt ttttgcgata
    27601 agctttaatg ctatgactat accactcttg catttctttt gatggtggtg tcatataatc
    27661 gccatacatc tgggttaaaa attggtcata ttttttggga acaggcaaca tacggccctc
    27721 aaactcagtt aaaatcagtt ctttaaaggt atcaactggg aagatttctt tcatcccttc
    27781 cttaccgatc ccaactcctc cttcatattg aggaatgttg gttacagcat ttttgactag
    27841 ttgatcaatt ttcttgtaaa agtagcgagg attgacaaat cggagagcgt accagctaca
    27901 taatctaaga aaatctttta gtttgctatc accgtgaact gctcgtgatt ttttgatgta
    27961 agctagttga cgaagggcca catacttata gctcttgtcg acaatgctca agtctgtaaa
    28021 ttgatcaatt gggaagacat cgatgaaaag gctggtatca tgacgcttgt acttaacatg
    28081 gtcttctata acagtagaag tatccaaaat cgatgcgaaa ttatggaagt accaagaaga
    28141 tgtatcgtag gaaagaacct tgtagcgagg gtgattttct tcttcaataa tcttcagtaa
    28201 acgctcataa tcctcacgat aaagggaaat atcaatatca tcatcccaag gaatcatacc
    28261 tttgtggcgg atggctccaa gcatggttcc ataactgaga aaataaggaa tatcatgttt
    28321 cttacaagtc tcatcaatat agtccagcag ggctagttga atttctttaa tttctttttt
    28381 ttctaaatat tgcatcctaa tcctccaatt tataagcgtg aaattcatga ctgtagaagc
    28441 gtttttcttc tggtggtagg gtcatataat ctccataaaa ttgtgtcaaa atagtatcaa
    28501 atttttcagg tgcaggaagg cttaaattct caaagggtaa atcgattgtt ttatcaaagg
    28561 tagcacttgg gaagacttcc ttttccttaa attttgaagg aataaaagcc atatactgcc
    28621 cattttcacg actatatttt tgaatttctt tctcgatttt atttgcaaaa taacgaggag
    28681 aaaccagtcg aaggagcaac caaaaggctg ttcgtatcca atcttttaaa aggctatcct
    28741 tatagacaat atttttatgt ttactgaaag acagcagttt gaagctttct agtttataac
    28801 aagtatcaat gaccttagga tcatcaaagc gatccatagg gaaaatatcg ataaagatac
    28861 cagactcata ggtttttgta tttcgagtat caataatttt agtcgtactg tcggttatct
    28921 tgataaagtt gttaaagtag ttcttatcag tttctaagga taggagctta tacttgcttt
    28981 tttccttttg aaaaatgtta ataaatcgtt ggtagtcttc tctaggcatg gataaatcaa
    29041 tatcgtcgtc ccaagggata aagccctcat gtcgaaccgc cccaatcaga gtaccgtagt
    29101 taataatata gttgatattg tgctttttac agagagtatc aatataattc aaaatttcta
    29161 attcaatttg tttggcatct tcaacggtta gttgtttcat tttaaactcc taagattttt
    29221 taaatttatt ttttaaggct aggacatggt ttaaaaattc atagaaaatg ctatcttttg
    29281 tgaagacaag tagactaata taagagatag ctgatagcaa gacaatcaaa ccagtattaa
    29341 tcaaaaatgg caaattaatg accatatcca caggatacac gaaattaatc aggaaataaa
    29401 ttgctacaaa ggaaagtgaa aagagagagt atcgaacagt atagctaaag atatgtccca
    29461 agtggatgag ttgttttcta tggatgaaaa tgatatagaa aacaagtaga gaagcctctg
    29521 ataacatagt tgtcagtaag tagtattcgg gagccacgat atggttgaaa aagaggagac
    29581 tattcaagcc caaattgagt agcccagcaa agactgtata gactgtgata cgtttttcat
    29641 agccattggt aaagagaatt tgggaaccaa gaatggtatc taaggccagg ataatcgtac
    29701 gaaaagcgaa gagagaggtc aagatgtcgc ctccgatata tttttcacta ccgtaaagta
    29761 ggatggcatt tggtcctaaa accatgagtc caaaactcag tggaatgata aagaagttaa
    29821 agattcgact acctctatta accagagaaa cataggcttc tttgtctcct ttccccagat
    29881 agtaactgag acgaggcaca ctcactccaa ttgcacctgt tacaacccca gctataacgg
    29941 tcacaattcg ctgagctatg gtatagtaac taacgttgac atcaatccct gttttaacga
    30001 ggaagaggcg atctaaaaaa gtgaagagca tattggcatt ggcaaagact aacatggctg
    30061 tcagagggag aaagagtggt ttaaaatcac ttaggtgaat cttaacaagt ttgatgtctc
    30121 ttttaatcca aaaataacta atcaggtagt taatcagcgt cgataaactc atcacaagtg
    30181 tatagacaac aatatcgtgt tcatttttaa caaataagaa aatagagacc agcatcagga
    30241 tacggatgaa ggcagttttg taaaagagaa aactgtaatt ttccagagct tcattgaccc
    30301 attcgattga aaaaatctgg gcaatgagtt gaatccccat aacaaggtag acctttttga
    30361 cgattggatt atcagtaaag aagagaggat aggctaggat atagacagca gtggtcaaaa
    30421 tcgtacaagc gatgcacaaa taaaaaagac tagaaaaggt tctgttaaga tcttttttgt
    30481 tatccttgac attactgata gcccttaaac cgtagttata gacaccataa gttgcaaagg
    30541 gcaagaaaaa tgacaaaata gtgtcgactg agttgaagta accatagtca gttcggtcca
    30601 agacacgcgc gacataggtt ccagttagga tgggaaaaat aatattcaag acacgaattc
    30661 ccatgtaaga tagagcattt aattttatac ttttcattca atttacctcg tttttcatta
    30721 tatcataaag ttagctaata agaaatgaag ggcagtaagt caagtaatca ctttgaagtt
    30781 tcaaatctta agttttaagt tttctttaag gaaagtatat tattctgaag gactctaaaa
    30841 tttcgcagcc atttattagt aattgctaca gaattcctag tcattactag aaatggacta
    30901 gtttctttga ataatagaac tgcataattc tcctattcta gaaggggagg accagtattt
    30961 cttttatgat aggactagat tgtggtataa tagagagaat aagttttttt agtaagacaa
    31021 aggagaaaat agatgattta tgcaggaatt cttgccggtg gaactggcac acgcatgggg
    31081 atcagtaact tgccaaaaca atttttagag ctaggtgatc gacctatttt gattcataca
    31141 attgaaaaat ttgtcttgga gccaagtatt gaaaaaattg tagttggtgt tcatggagac
    31201 tgggtttctc atgcagaaga tcttgtagat aaatatcttc ctctttataa ggaacgtatc
    31261 atcattacaa agggtggtgc tgaccgcaat acaagtatta agaaaatcat tgaagccatt
    31321 gatgcttatc gtccgcttac tccagaggat atcgttgtta cccacgattc tgttcgtcca
    31381 tttattacac ttcgcatgat tcaggacagt atccaacttg cccaaaatca tgacgcagtg
    31441 gacacagtgg tagaagcggt tgatactatc gttgaaagta ccaatggtca atttattaca
    31501 gatattccaa atcgtgctca cctttatcaa ggacaaacac ctcaaacatt ccgttgcaag
    31561 gacttcatgg acctttatgg atctctttct gatgaagaga aggaaatctt gacagatgca
    31621 tgtaaaatct ttgtgatcaa aggaaaagat gtggccttgg ccaaaggtga atactcaaat
    31681 ctgaagatta caaccgtaac agatttgaag attgcaaaaa gtatgattga gaaagactag
    31741 taaaatgatt aatcaaattt atcaactaac taagcctaag tttatcaatg tcaaatatca
    31801 ggaagaggct attgaccaag agaatcatat ccttatccgt cccaactaca tggctgtctg
    31861 tcatgcggat cagcgttact atcagggaaa acgtgatccc aagattttga ataaaaagct
    31921 tccaatggca atgattcacg agtcatgtgg aaccgtcatt tctgacccga ccggaaccta
    31981 cgaggttggt caaaaagttg tcatgattcc caatcagtct cctatgcaga gtgatgaaga
    32041 attctatgaa aactacatga cagggaccca tttcttgtct agtggatttg atggctttat
    32101 gagagagttt gtttctctcc ctaaagatcg tgtggtggct tatgatgcta ttgaagatac
    32161 ggttgcagcc attacagagt ttgtcagtgt gggcatgcac gctatgaatc gtctattgac
    32221 tcttgctcat agcaagcggg agcggatcgc cgttattgga gatggaagtt tagcttttgt
    32281 ggttgccaat attatcaact atactttgcc agaagcagag attgtggtta ttggtcgtca
    32341 ttgggaaaag ttggaactct tctcatttgc caaagaatgc tatattacgg ataatattcc
    32401 tgaagagttg gcctttgacc atgcttttga atgttgtggt ggtgatggta ctggaccagc
    32461 tattaatgac ttgattcgct acattcgtcc tcagggaacg attctcatga tgggagttag
    32521 cgaatataaa gtcaatctca atactcgcga tgccttagaa aagggcttga ttttggttgg
    32581 gtcatctcgt tctggtcgca ttgattttaa aaatgctatc caaatgatgg aagtcaagaa
    32641 atttgccaat cgtcttaaaa atatccttta tctagaagaa cctgtaagag aaattaaaga
    32701 tattcatcgt gtctttgcaa ccgatttaaa cacagccttt aaaacagtgt ttaagtggga
    32761 agtataagta ctggaggtta attgtggaga aaatcattaa agaaaaaatt tcttccttac
    32821 ttagtcaaga agaggaagtc ctcagtgttg aacaactggg tggaatgacc aatcaaaact
    32881 atttggccaa aacaacaaat aagcaataca ttgttaaatt ctttggtaaa gggacagaaa
    32941 agcttatcaa tcgacaagat gaaaagtaca atcttgaact actaaaggat ttaggcttag
    33001 atgtaaaaaa ttatcttttt gatattgaag ctggtatcaa agtaaatgag tatatcgaat
    33061 ctgcgattac gcttgattca acgtcaatca agaccaagtt cgacaaaatt gctccaatat
    33121 tacaaactat tcatacgtct gctaaggaat taagaggaga atttgctcct tttgaagaaa
    33181 tcaaaaaata cgaatccttg attgaagaac aaattcctta tgccaactat gaatctgtta
    33241 gaaatgcagt cttctcctta gagaaaagac tggctgactt aggtgttgac agaaaatctt
    33301 gtcatatcga tttggtgcct gaaaacttta tcgaatcacc tcaaggacga ctttatttga
    33361 ttgactggga atattcatca atgaatgatc caatgtggga tttggctgcc ctctttttag
    33421 agtctgaatt cacttcccaa gaggaagaaa ctttcttatc tcactatgag agtgaccaaa
    33481 caccggtttc tcatgaaaag attgctattt ataaaatttt acaagatact atttggagtc
    33541 tatggactgt ctataaggaa gagcaaggtg aagattttgg tgactatggt gtgaatcgtt
    33601 accaaagagc tgttaaaggt ttggcttctt atggaggttc agatgaaaag taaaaacgga
    33661 gttccttttg gccttctctc aggtattttc tggggcttgg gtctaacggt tagtgcttat
    33721 atcttttcga tttttacaga tttgtcaccc tttgtggtgg ctgcagctca tgattttttg
    33781 agcatcttta tcttactagc ttttctcttg gtaaaagaag ggaaagttcg cctctcaatt
    33841 ttcttaaata ttcgcaatgt cagtgttatc atcggagcct tgctagcagg ccctatcggt
    33901 atgcaggcca atctttatgc agttaagtat atcggaagtt ctttagcttc atctgtatcg
    33961 gctatttacc ctgcgatttc agttctattg gctttcttct ttttgaagca caagatttcg
    34021 aaaaatactg tatttgggat tgtcttgatt attggaggga ttattgccca gacctataaa
    34081 gttgaacagg ttaattcttt ctacattggg attctttgtg ctttggtttg tgctattgca
    34141 tggggaagtg agagtgttct tagctctttt gccatggaaa gtgaattgag tgaaatcgaa
    34201 gccctcttaa tccgtcaagt aacttcgttc ttgtcctatc ttgtgattgt gctcttctct
    34261 catcagtcat ttactgcagt agccaatgga caattgctag gtctcatgat tgtttttgca
    34321 gcctttgata tgatttccta cttggcttat tatatcgcta tcaatcgctt gcaaccagcc
    34381 aaggctacag gcttgaacgt gagctatgta gtatggacgg tcttgtttgc agttgttttc
    34441 ttgggtgcac cgctagatat gctgaccatt atgacgtcac ttgtcgtcat tgctggagtt
    34501 tatattatta ttaaagaata aaggagattc gtgtgaaagc catcatctta gcagcgggat
    34561 tgggaactcg cttgcgtcct atgactgaaa atacccctaa agccttggtt caggttaatc
    34621 aaaaaccttt gattgagtac caaattgagt ttctcaaaga aaaaggaatc aatgacatca
    34681 tcatcattgt tggttatctt aaagaacaat tcgattactt gaaagagaaa tacggtgttc
    34741 gtctcgtttt caatgataaa tacgctgact acaataactt ttactctctc tatcttgtaa
    34801 aagaagaatt agccaatagt tatgttatcg atgccgataa ctatctcttt aaaaatatgt
    34861 tccgcaatga tttgacacgt tctacttatt ttagtgtcta tcgtgaagat tgtaccaacg
    34921 aatggttctt ggtctatgga gatgactaca aggttcaaaa cattattgtt gatagcaagg
    34981 caggtcgcat ccttagtggt gtatccttct gggatgctcc aacagcagaa aaaattgtta
    35041 gctttatcga taaggcttat gcaagcggcg aatttgttga tctctattgg gacaatatgg
    35101 ttaaggataa catcaaagag ctagatgtct atgttgaaga attagaaggc aatagcattt
    35161 atgagattga tagtgtccaa gactatcata aattagaaga aattcttaaa aacgaaaatt
    35221 aaaagcttcc aacatctgac aaaatagtcg gatgtttttt tgatttttta cgaactttta
    35281 cgaatagata gatgagtaga aaaagaaatg gagttattta tgaaaatcac aaactatgaa
    35341 atctataagt taaaaaaatc aggtttgacc aatcaacaga ttttgaaagt tctagaatac
    35401 ggtgaaaatg ttgatcagga gcttttgttg ggtgatattg cagatatatc aggttgccgt
    35461 aatccagccg tttttatgga acgttatttt cagatagacg atgcgcattt gtcgaaagag
    35521 tttcaaaaat ttccatcttt ctctatttta gatgactgtt atccttggga tttgagtgaa
    35581 atatatgatg cgcctgtact tttattttac aagggaaatc ttgacctcct gaaattcccg
    35641 aaggtagcgg tcgtgggcag tcgtgcttgt agcaaacagg gagctaaatc agttgaaaaa
    35701 gtcattcaag gcttggaaaa tgaactggtt attgtcagtg gtctggccaa gggcattgac
    35761 acagcagctc atatggcagc tcttcagaat ggcggaaaaa ccattgcagt gattggaaca
    35821 ggactggatg tgttttatcc taaagccaat aaacgcttgc aagactacat cggcaatgac
    35881 catctggttc taagtgaata tggacctggc gaacaacctc tgaaatttca ttttcctgcc
    35941 cgtaatcgca tcattgctgg actttgtcgt ggtgtgattg tagcagaggc taagatgcgt
    36001 tcaggtagtc tcattacgtg tgagcgagca atggaagaag gacgcgatgt ctttgctatt
    36061 cctggtagca ttttagatgg actatcagac ggttgccatc atttgattca agaaggagca
    36121 aaattggtca ccagtgggca agatgttctt gcggaatttg aattttaaaa atgacctaag
    36181 ctagaattct aagaaaaaat caattttaag agaaaatgaa cccaacattt ccataataaa
    36241 acgcatatta gcaagttttt aacacttgat aatatgcgtt ttttctaagt ggattagtag
    36301 agtagaggat ttttctcata taatactctt cgaaaatctc ttcaaactac gtcagcttcc
    36361 atctgcaacc tcaaaacagt attttgagct gacttcgtca gtcttatcta caacctcaaa
    36421 gcagtgcttt gagcaacctg tggctagctt cctagtttgc gctttgattt tcattgagta
    36481 taagggaaag tatagtgaat tgaaataaga tgtgaacaac tctatcagga aagtcaaatt
    36541 aatttataga aatattttag cagccaaggt gcactgttat agattcaata cactataatt
    36601 tagtgtaatt gagaaaggag aaatgattgt gattgatgtt ggctaggtta tgttcaatga
    36661 ttcctaccgt ctcaaatctt gtcagtaagg aaaaataaat tcttcaaaag tagagattac
    36721 aaggcttgtt taagaaagaa ttcaaagacc ttgacaaata aaaataaaat ggttattata
    36781 aaaaatggtc tgaaatagat gatgatactt ttcgaaaatc tttttacgtc agctcagctt
    36841 tgccttgctg tgttttgagc aagctacggt tagcttccga gtttgatttt catttactag
    36901 aaatgaaact gatgagagat atcagtagac atttgagtca ggatattatg gaaaatgata
    36961 aaaagagctc gtgagattgg catatcagac tactaaagta ttgagtttgt taggatttta
    37021 gcgactagtt agctgggaaa ggaagatatt tgtgacaaat aataaactgt attcgttgat
    37081 agaatttaga aataaaatat atgaagaatt agaactttcc agaagtgatt tagcgatttt
    37141 actatgtgcc atgcttatcg cctctatcgg attaaatatg gattcgactc ccgtgattat
    37201 tggagccatg ttaatctctc ctttgatgac acctattctg ggagtggggc tctctctagc
    37261 tatatttgat tttaaattgt taagaaaatc ttttaaaata ttagctattc aaattcttgc
    37321 cagtttaata gcttcaacac tttattttta tctttctccc atttcgtatg ctagttcgga
    37381 aattgttgct agaacctctc cgactatttg ggatgttctc attgcttttg taggagggat
    37441 agcaggtatt attggtgcta ggaaaaaaga gaccaataat attgttcctg gtgttgctat
    37501 tgcaaccgcc ttgatgcctc ctctttgtac agtaggttat gctattgctt ctgctaatct
    37561 aaaatttatc ataggctcct cttacctatt cctcatcaat tgtagcttta ttgtcattgc
    37621 gacttatata ggtgttaggt tgatgatggt taagaaacat tattttaaag ataatgaaga
    37681 agactctaaa atgcgtagga ttttgcttct agttgctgtt ttgctgatga ttccgagttt
    37741 catctctgca acgactttag tgagagaaac gttgaaaaaa gagtccctta agaaatttat
    37801 atcagagcag tttcaggggc ataatatttt gaaaaaaacc tattctaaaa agactcatac
    37861 cctaaagcta accatttcag gaaattattt gacagaagaa gaactcgata tgatttcaag
    37921 taagagaggt gactatggtt taagtgatgt ttctgttcaa gtttcacaat tgtctgattc
    37981 agaacaactt agtaaggaag aactggtgga gtatttcttc cagtatatca aggataagga
    38041 agcaaaagaa aaggaaaaag ctaataagtt ttatacagag tctgaggagc aataatttct
    38101 tgagaatagc tggtttctct cgtgagtctt ctatgtatat caaaggaaga ctgaggtttt
    38161 aagtataaaa cttttcttct attatagtag ctaagtcttg acagggttca aaaaatggtt
    38221 tacactttat aaagtttatt actttgaaaa ggtgtgatac tgtggctacg gcaacaaaaa
    38281 agaaaaaatc aacagttaaa aaaaatctag tcatcgtgga gtcgcctgct aaggccaaga
    38341 cgattgaaaa atatctaggc agaaactaca aggttttagc cagtgtcggg catatccgtg
    38401 atttgaagaa atccagtatg tccgtcgata ttgaaaataa ttatgaaccg caatatatca
    38461 atatccgagg aaaaggccct cttatcaatg acttgaaaaa agaagctaaa aaagctaata
    38521 aagtttttct cgcgagtgac ccggaccgtg aaggagaagc gatttcttgg catttggccc
    38581 atattctcaa cttggatgaa aatgatgcca accgtgtggt cttcaatgaa atcaccaagg
    38641 atgcagtcaa aaatgctttt aaagaacctc gtaagatcga tatggacttg gtcgatgccc
    38701 aacaagctcg tcggatcttg gatcgcttgg tagggtattc gatttcgcct attttgtgga
    38761 agaaggtcaa gaagggcttg tcagcaggtc gcgttcagtc cattgccctt aaactcatca
    38821 ttgaccgtga aaatgaaatc aatgccttcc agccagaaga atactggaca gttgatgctg
    38881 tctttaaaaa gggaaccaaa caatttcatg cttccttcta tggagtagat ggtaaaaaga
    38941 tgaaactgac cagcaatgac gaagtcaagg aagtcttgtc tcgtctgact agtaaagact
    39001 tttcagtaga tcaggtggat aagaaagagc gcaagcgcaa tgctccttta ccctatacca
    39061 cttcatctat gcagatggat gctgccaata aaatcaattt ccgtactcga aaaaccatga
    39121 tggttgccca acagctctat gaaggaatta atattggttc tggtgttcaa ggtttgatta
    39181 cctatatgcg taccgattcg actcgtatca gtcctgtagc gcaaaatgag gcggcaagct
    39241 tcattacgga tcgttttggt agcaagtatt ctaagcacgg tagcaaggtc aaaaacgcat
    39301 caggtgctca ggatgcccat gaggctattc gtccgtcaag tgtctttaat acaccagaaa
    39361 gcatcgctaa gtatctggac aaggatcagc tcaagctata tacccttatc tggaatcgtt
    39421 ttgtggctag ccagatgaca gcggccgttt ttgataccat ggctgttaaa ttgtctcaaa
    39481 atggagttca atttgctgcc aatggtagtc aggttaagtt tgatggttat cttgccattt
    39541 ataatgattc tgacaagaat aagatgttac cggacatggt tgttggagat gtggtcaaac
    39601 aggtcaatag caaaccagag caacatttca cccaaccgcc tgcccgttat tctgaagcaa
    39661 cactgattaa aaccttagag gaaaatgggg ttggacgtcc atcaacctat gcgccaacca
    39721 ttgaaaccat tcagaaacgt tattatgttc gcctggcagc caaacgtttt gaaccgacag
    39781 agttgggaga aattgtcaat aagctcatcg ttgaatattt cccagatatc gtaaacgtga
    39841 ccttcacagc tgaaatggaa ggtaaactgg atgatgtcga agttggaaaa gagcagtggc
    39901 gacgggtcat tgatgctttt tacaaaccat tctctaaaga agttgccaag gctgaagaag
    39961 aaatggaaaa aatccagatt aaggatgaac cagctggatt tgactgtgaa gtgtgtggca
    40021 gtccaatggt cattaaactt ggtcgttttg gtaaattcta cgcttgtagc aatttcccag
    40081 attgccgtca tacccaagca atcgtgaaag agattggtgt tgagtgtcca agctgtcatc
    40141 agggacaaat tattgagcga aaaaccaagc gtaatcgcct attctatggt tgcaatcgct
    40201 atccagaatg tgaatttacc tcttgggaca agcctgttgg tcgtgactgt ccaaaatgtg
    40261 gcaacttcct catggagaaa aaagtccgtg gtggtggcaa gcaggttgtt tgtagcaaag
    40321 gcgactacga ggaagaaaag attaaataag aggaggggcc cgaaagtaaa tttcaggctc
    40381 cttttggtta gaacttgaca aaatacatca ttttatgcga aactagaaga agattatttt
    40441 atactcaatg agaatcaaag agcaaattag aaagctagtc gcaggttgct caaagcacta
    40501 ctttgaggtt gaagatggaa gctgacctgg tttgaagaga ttttcgaaga gtattaacta
    40561 ggagaagtta tgcgtattat ctatctaatt attggttttt tatcgctgac cttggctatt
    40621 gttggggttg ttttaccctt gttgcctaca acacctttcc ttttgttgtc tattgcttgt
    40681 ttctccagaa gttccaagcg attcgaagat tggctttatc ataccaagct ctatcaagca
    40741 tatgtagctg attttcgtga gaccaagtct attgcgcgtg aacgaaagaa aaaaatcatc
    40801 gtctctatct acgtcttgat gggaatttct atttattttg cacctctttt accagtcaaa
    40861 atcggtctgg gtgctttgac catctttatt acttattatc tcttcaaggt cattccagac
    40921 aaagaatagt taaaacagta gttatttgcc ttgataaaat tgaaagcata ttcataacaa
    40981 tatgatataa taaaattgaa gtaatattca aggagaatca aatgatttac gaattttgtg
    41041 ctgaaaatgt gactttactt gaaaaagcga tgcaggctgg agctcgtcgg attgaactct
    41101 gtgataatct agcagttggt gggacaacac ccagctatgg agtgactaag gcagcggttg
    41161 aactggcagc taactacgat acaaccatca tgaccatgat tcggccacgt ggtggtgact
    41221 ttgtctataa tgacctagaa attgctatca tgctagaaga cattcgtttg actgctcagg
    41281 ctggaagtca aggggttgta tttggagctt taactgctga taaaaagttg gataagccta
    41341 atctggaaaa gttaattgct gcatcaaaag gaatggaaat tgtctttcac atggcctttg
    41401 atgaactaag tgatgaagat caaccggaag ctattgactg gctcagtcaa gccggtgtca
    41461 ctcgtatcct aactcgtgct ggtgtgtctg gcgactcctt agaaaaacgt tttgttcact
    41521 atcacagaat tttggagtac gctaaaggta aaattgaaat tctaccaggt ggggggattg
    41581 accttgaaaa ccgtcaaacc tttatcgacc aggtgggggt aacacaattg catggtacta
    41641 aggttgtttt ttaaaaaata gaaaggaact gctagctttg ggtagcagtt ttcacttatg
    41701 tttgaaattt ttaaatccta tcaatttaat caagaaaagg ctcatgatta tggttttata
    41761 gaaaatagcg aagtctggac atatagttgc cagattttgc aaggtgactt tgtcatgact
    41821 gtgtccatca ctgctgataa tgtgaacttt caagtctttg accaagagac tggtgacctc
    41881 tatcctcacg tttatatgga aagcatgagg ggaagttttg tcggaaatgt ccgtgaggct
    41941 tgtctggaga ttctttacca gattcggaag gcttgttttg atgtgcaaga ttttatctgt
    42001 catcagacta agcgtatcat gactcaagtt caggaaaagt atggaaacca gttggagtat
    42061 ctgtgggaaa aatcgcctga tacagctgta ttgcgccatg aaggcaatca aaagtggtat
    42121 gccgtcttga tgaaaatctc ttggaataag ctggaaaagg gcagagaagg acaagtggaa
    42181 gcagtcaacc tcaagcatga ccaagtagct aatttgcttt cacaaaaggg gatttatcca
    42241 gccttccata tgagcaagcg ctactggatt agtgtgtccc ttgatgatac tttatcagat
    42301 gaagaagtac tggaattgat agaaaaaagt tggaacttaa cctctaaaaa atgaaatatt
    42361 ttaataattt tcatgaactt tcaattagct aaatattctt tactgaagag atttttagaa
    42421 aatataggat ttaccacact agaggaatat ggtgccatct tcaaatacct gattgagaat
    42481 gtcaagacgg atcgtcagat catctattcg cctcactgtc atgatgacct cggaatggca
    42541 gtggcaaata gccttgctgc tgtcaagaat ggtgcaggac gtgttgaagg gactatcaat
    42601 ggtattaggg agcgagctga aaatgctgct ttggaagaaa ttgcagtggc tctcaatatt
    42661 cgccaagatt actaccaagt agaaaccagt attgtcctaa atgagaccat caatacgtca
    42721 gaaatggttt ctcgcttctc tggtattcca gttcctaaaa acaaagccgt cgttggtggc
    42781 aataccttct cccacgaatc tggtattcac caagatggag tccttaaaaa tcctctcact
    42841 tatgagatca tcacacctga attggttggt gttaagattc tgcttggaaa attatctggt
    42901 cgccatgctt ttgttgagaa actgagagaa ttggccctag attttacaga agaggatatc
    42961 aaaccactct ttgctaagtt caaggcactg gtcgataaga agcaagaaat cacagatgca
    43021 gatattcgag ctttggtagc tggaaccatg gttgaaaatc cagaaggctt ccactttgat
    43081 gatttacaac ttcaaactca tgcagataat gacattgaag cgctcgttag cctagccaat
    43141 atggatggtg agaaagtcga atttaatgcg acagggcaag gttccgttga agcaatcttt
    43201 aatgctatcg ataagttctt taaccaatct gttcgtttgg tgtcctacac tatcgatgcg
    43261 gtaacagatg gaatcgatac ccaggatcgg gttttggtca ctgttgaaaa cagagataca
    43321 gaaaccatct ttaatgcagc agggcttgat tttgatgtgt tgaaggcttc tgctattgtc
    43381 tatataaacg ctaatacctt tgttcaaaaa gagaatgcag gtgagatggg acgcagtgtt
    43441 tcttaccacg atatgcctag tgtgtaaagg agaaggctat ggcaaagaaa atagtagctc
    43501 tagcaggaga cggaattggc ccagaaatca tggaggttgg tttagaagtt ctggaggctc
    43561 tagctgaaaa aacaggtttt gactatgaga ttgacagacg accgttcgga ggtgcagata
    43621 ttgatgcagc atgacctccc ttacctgatg aaacccttaa ggcaagtagg gaagcagatg
    43681 ctatcctact agtagctatc ggtagtcctc agtatgatgg agcagtggtt cgccctgaac
    43741 aaggcctgat ggctctccgt aaggaactca atctttacgc taatattcgt cctgtaaaaa
    43801 tctttgacag tctcaagcat ttgtcactac tcaaactgga acgaattgct ggtgtagact
    43861 ttgtcgtggt gcgtgaattg acaggcggga tttactttgg agatcatatt cttgaagagc
    43921 gcaatgcgcg tgatatcaac gactatagct atgaggaagt ggagcggatt attcgcaaag
    43981 cctttgaaat tgcaagaaat cgcagaaaaa tcgttactag tatcgataag caaaatgttc
    44041 tagcgacctc aaaactctgg cggaaagtag ctgaggaagt cgcacaggat ttcccagatg
    44101 taaccttgga acatcagctg gtagactcag ctgctatgct tatgattacc aatcctgcta
    44161 agtttgatgt tattgtaacg gagaatcttt ttggagatat tttatctgat gaatcaagcg
    44221 tcttatctgg tacacttggg gttatgccat cagccagtca ttctgaaaat ggaccaagtc
    44281 tctatgaacc tattcacagt tcagcacctg atattgcagg tcaaggaatt gccaatccta
    44341 tttccatgat tttatcagtt tccatgatgt tgagagatag tttcggacgt tatgaggatg
    44401 cagagcgtat caaacgtgct gttgagacaa gtctggcggc aggaatttta acgagagata
    44461 taggaggtca ggcttcaaca aaggaaatga cggaagctat tattgcaagg ttatgaagtt
    44521 agacgaaaaa attactctag tccttttgat ttggaatgtc atcattttct tgatttatgg
    44581 tattgacaaa tctaaggcaa ggagaagagt ttggcgcatc cctgagaaaa tcttacttat
    44641 tttagccttt acttttggtg gttttggtgc ctggctagca ggaatcatct ttcaccacaa
    44701 gactcgaaaa tggtacttta aaatagtttg gtttcttggg atggtgacca cactagtagc
    44761 cttatatttt atttggaggt aatggatggc agggtcttcg agggaatacg ctgcttgggc
    44821 tctagcggac tatggtttta aggtcgtgat tgcaggatct ttcggtgaca ttcattacaa
    44881 taatgaactc aataatggca tgttgccaat cgttcagcct agagaggtta gagagaaact
    44941 agcccagcta aaaccaaccg accaggtaac tgtggacttg gaacaacaaa aaatcatctc
    45001 accagttgaa gaattcacct tcgagataga tagcgagtgg aaacataaac tcctaaatag
    45061 tttggatgat atcggtatta ccttgcagta tgaagagttg attgctgctt atgaaaaaca
    45121 acgaccagcc tactggcagg attagaaaaa atagaaaagg agatatagta aactgaaata
    45181 agatgtaaac aaatgaattg gagcttaaca tccatttcca gcaatttttt agaaactaca
    45241 gtggactatt ctggattcaa cacattataa aattatgaca aaacacattc acaagaaggc
    45301 tacgacattt taaaaggtga gggcggatgt atcgtttgcc ctactaaagt tggttacatt
    45361 atcatgacca gtgacaaggc aggacttgag cgtaagttcg cagccaaaga acgtaagcgt
    45421 aacaaaccag gtgttgttct ctgcggtagc atggatgaac tttgcgcttt agcgcaactc
    45481 aacccagaaa ttgaagcatt ctactaaaaa cattgggatg aagatattct tcttggttgt
    45541 atccttcctt ggaaaccaga agcctttgaa aaactcaaag catacgggga tggccgtgaa
    45601 gaacttatga ctgatgtacg tggtactagc tgttttgtta tcaagtttgg aaaagcaggt
    45661 gaacaattgg ctgccaagct ttgggaagaa ggtaaaatgg tctacgcctc atctgcttca
    45721 atgacaaaac gattgaaact cgctatgagc aaggtgtaat ggtgtctatg gtcgataagg
    45781 acggcaaact catcccagaa caaggaggag cacgttcaac ttcaccagct ccagttgtga
    45841 tccgtaaagg gcttgacatt gatatagtaa aatgaagtaa gagcaggaca aattaatcag
    45901 gacagtcaaa tcgatttcta acaatgtttt agaagtagag gtgtactatt ctagtttcaa
    45961 tccactataa aatcatgatg cacctgtcag atacttttaa ctcatgggac taccgtcagg
    46021 ttgagtatta ttaggataga gaagaagtct agtgttaagg acattacagc tcataatact
    46081 aggctttttt atagaaattc ttttcttttt ctataggata tggtattcta tgtagaaaat
    46141 atatgttaat aagtaatgcc aatatttaaa catcattagt aaaaggagtt agattgatga
    46201 ataaaagaaa agttagttta gaagattttt ataaatggta tagtctaaat aaagaagagt
    46261 tattaaataa ggcaactgtt ggtgaaaagt ttaatgataa attaaaagaa gagtttctcc
    46321 aggaatggcc tttggatagg attttaacaa tgtcaatcga tgaatatgta ataggaaagg
    46381 gacagcaaaa taagtcttta tgctacgctc ttgagaaggg aaaatacaaa aatctatttc
    46441 ttggaatttc tggtggctca gcttcaaaat ttggtattta ttggaataaa aaaacaaaca
    46501 aatataaaga tcaagctaat aatgagattt cagagttgga tcagcgattt tcaaaattaa
    46561 aatcagattt gtatgaaatt atcaaagaag gtattcgttt taactttgaa aatcctattt
    46621 ttgatatgaa aagatcaaca aatgaattta ttggtcgttc tgctatggtg acaaaattac
    46681 tttgtatcta tactgaggga gatcctttct ttggtgtaaa tattaatagt cagaaagaat
    46741 tttggaacca ctttgtttct cagacaaatc aaggtggacc ttatctgcaa aatcataaaa
    46801 taattgaact gatgtccaaa acttatcctg agttggagcc atcgaaatta ggaactatgc
    46861 tttttgagta ttctaagctt tttatggaaa ataaggaaga caatagtaca atggattcat
    46921 caaacaattt tcgtcatcaa ttaactcaat ctctattaaa gtctccaaac cttatccttc
    46981 gtggtgctcc tggcacagga aagacttatc ttgctaaaga aattgccaaa gaattaacgg
    47041 atggcaacga agatcaaatc ggatttgtac aatttcaccc atcatatgat tatacggatt
    47101 ttgtagaagg tttaagacca gtatcaaatg gggatggagc tattgagttt aggctacagg
    47161 acggtatttt taaagatttt tgtcagaaag caaaagaaac ccaattgatt ggaggacaag
    47221 ataattttga tgaggcttgg gattcttact tagaatatat aaatgttgct gaagaaaaag
    47281 aatatataac aaaaacatct tacttatctg ttaatagtag acaaaatttg tcagtaaatt
    47341 atgatagtgg tgttccagga tggtcactac ctagcaaata tgtttacgag ttgtataaag
    47401 ataaaaatta taataagcaa gaatactaca aaagtggtgg aaaaactgtc ctagaaacat
    47461 tgagaaagag atttggtttg aaagactatg tttccccaac agaaattgat actgataaga
    47521 aattcgtttt catcatcgat gaaatcaatc gtggggagat ttctaagatt tttggcgaac
    47581 tctttttctc tatcgaccct ggctatcgtg gtgaaaaagg aagtgtttct acccaatatg
    47641 caaatctaca cgaaactgat gaaaagttct atatccccga aaatgtttac atcatcggaa
    47701 ctatgaatga tattgatcgt tcagtggata cctttgattt tgctatgcgt cgtcgttttc
    47761 gttttgttga agttactgcc gagggtcaag ttggcatgtt ggataaagag ctgaatatcc
    47821 atgcagaaga agcaaaaatt cgtctaagaa acttgaacgc tgctatcgaa aatgttcagg
    47881 aattaaacag tcattatcat attggaccaa gttattttct taagttgaag gatgtagatt
    47941 ttgactatga attactctgg tccgattata ttaagcctct cctagaagac tacttgcgag
    48001 gttcttatga tgaggttgaa actttggaaa ctttgaaaaa agcatttgaa ctgacaaata
    48061 atgagcaaaa agatcaggca gtagctgatg acaatgaaag cgatgaaaac gatgatgcgg
    48121 attactgata atcaacacaa gattattaaa gaaaaatttg ttgaagaata tcctaaacta
    48181 agcaatcttc ttttagacag aaccttggaa agtctatccc aagatgaacg tattttcatt
    48241 tttccaaatg atttgactca tactccagat ttggataaaa aacaaaagat tttggaaacg
    48301 atcaatcagg aaatcaagac aggaaatgtg attggttttc ttggatatgg tcaggaaaga
    48361 ttaacgattt cctcacgatt ttctgatgag agtaatgacc attttttgca ttatctctta
    48421 aacaaggttc ttcatatcaa tctcactagt ttagatgttg ctttgtctcg tgaagagagg
    48481 ctttatcaac ttttgatgta tctcttcccc aagtatctac aagctgctat tcgaaaaggt
    48541 ctttataagg aatatcatcg attttctcat aacgacagtc atgttaaggg agtgattgat
    48601 gtaagaaacc atctcaagaa aaatcttcct ttcacgggaa atattgccta cacaacgaga
    48661 gagttcacct atgataatcc cctcatgcag ttggtccgtc acactattga atacattaag
    48721 aatcagaaaa gcattggtca aggggtacta gataatctct caactagtcg tgaaaacgta
    48781 tctgaaatcg tgcgtgtaac gccctcttat aaactagctg atcgtgctaa gattattcgg
    48841 ggaaatcaat ctaaacctat acgtcatgca tactttcacg agtacagaaa cttacaagaa
    48901 ctttgtctga tgatcctaaa ccaagaaaag cacggtttag ggtatcaaga tcaaaaaatc
    48961 tatggtattc tctttgatgt tgcctggctt tgggaagagt atgtttacac cttgttgcca
    49021 aaaggttttg tacatcccag aaataaggat aagacggatg gaatttcagt attttctgtt
    49081 gggaaacgaa aagtatatcc agatttttat gacagagaac gaaagattgt tctagatgca
    49141 aaatataaaa aactggaatt gactgaaaaa ggaatcaatc gtgaggactt attccagctg
    49201 atttcctatt cttatatttt aaaagctgag aaggctggac ttgtttttcc gagcaaggac
    49261 aaggttattg ataatgagat gggaaaccta gcaggttatg gagctttgtt gaagaaatgg
    49321 tctatccaaa ttcctcagaa gtcttcatct tatagtgcat tttgtaaaat gatggaaaat
    49381 tcagattata gtgcattttg taaaatgatg gaaaattcag aagaaaattt taaagcgatt
    49441 attgatgaag aagtggggag aaaataattt cccctctttc ttttattttt aacacaagta
    49501 aaacccgaac aatatatttc aattcataaa ataatttgac aaaaactgta ctttggttta
    49561 taataaatta aggaaacgtc ggaaaagacg tagtgatgcg agagcatagg taggtcatta
    49621 caaaagaaac gagacatcga tatgttaaat gaatttccaa tttttgatta cgaagatatt
    49681 caattgattc caaataaatg tgtcattaaa agccgtgcag aagcggatac aagtgtcact
    49741 ttaggaaatc acacctttaa actacctgtt gtgccagcga atatgcagac gattttggat
    49801 gaaaatgtag cagagcaact ggctaaaggt ggttacttct acattatgca ccgttttgat
    49861 gaggcaggac gcattccttt tattaaacaa atgcacgatc aagggctcat tgcttccatc
    49921 tctgtcggtg ttaaggacta tgagtatgat tttgttagcc agctcaagac tgatgctcct
    49981 gagtatatca ctattgatat tgctcatggt catgcggata gcgtgatttc tatgattcaa
    50041 catatcaaga aagaattgcc agataccttt gtcattgctg gaaatgtggg aacaccagaa
    50101 gctgtgcgtg aattggaaaa tgctggtgcg gatgctacta aggtcggaat cggtcccggt
    50161 aaggtttgta tcaccaaggt taagactggt tttggtacag gtggttggca gttggctgct
    50221 ctacgctggt gtgccaaggc tgcgcgtaaa ccgattatcg ctgatggagg aattcgtact
    50281 cacggtgata ttgctaagtc tatccgcttc ggtgctagca tgatcatgat tggttccctc
    50341 tttgcaggac acattgaaag tccagggaaa acgattgaag tcgatggtga acagttcaaa
    50401 gaatattatg gttcagcctc acaatatcaa aaaggtgctt acaaaaatgt ggaaggcaaa
    50461 cgtatcttgc ttcctgctaa aggtcatctg caagacactt taactgagat ggaacaagac
    50521 cttcaaagtg ctatttctta tgcaggtgga cgtcaggttg ctgaccttaa acacgttgat
    50581 tatgtgatcg tgaaaaactc catctggaat ggggatgctt cccactaaga cggggtcttt
    50641 gaccaaaaaa cttgttatta gagcaaattt ctgttataat aaaacaagtt tccaccctta
    50701 gtgtaatgga tatcacgtaa gattccggtt cttgagatgg gggttcgatt ccctcagggt
    50761 ggatgtaaac atcctaaaaa gcctttaata gggctttttt ctttatcctg acccaaattt
    50821 gccgctaaaa ctgagaatct ctgtctaaag aattcccaaa tgctttccag tcccgtttta
    50881 gagtgactca gggggctttt tttgatataa taaaaaggac tgttatcagt tagaaagagg
    50941 ttggtatgaa agaattacaa actgtactaa agaatcattt tgcaatcgaa tttgcagaca
    51001 aaaatttact ggaaactgcc tttactcata cgagttatgc caatgagcac cgcctcttaa
    51061 aaatttcaca caatgaacgc ttggaatttt taggagacgc tgttctacag ttattgattt
    51121 cagaatatct atataaaaaa tatcctaaaa agcctgaagg tgacctatca aaactccgtg
    51181 ctatgattgt ccgtgaggag agtttagctg gttttgcgcg tgattgccag tttgaccagt
    51241 ttatcaagtt gggtaaaggg gaagaaaaat caggtggtcg caatcgtgac accattcttg
    51301 gtgatgcctt tgaagccttt cttggtgccc ttcttttgga taaggatgtg gccaaggtca
    51361 aggaatttat ctatcaagtc atgattccta aggttgaagc aggcgaattt gagatgatta
    51421 cagactataa aacccatctc caagagttac ttcaggtcaa tggtgatgtg gctattcgtt
    51481 atcaggtgat ttctgaaaca gggcctgctc acgataaggt ctttgatgta gaagttcttg
    51541 ttgaaggtaa gagcatcggt caaggccaag gtcgttctaa gaaattagca gagcaggaag
    51601 ctgccaaaaa tgccgttgag aaggggctgg attcatgtat ttaaaggaaa tcgaaattca
    51661 ggggttcaag tcttttgctg ataagaccaa ggtcgttttt gaccaaggtg tgacggcagt
    51721 tgttggaccc aatggatctg gaaagtccaa tattacagaa agtctgcgtt gggctttggg
    51781 ggagtctagt gtcaagagtc tccgtggggg caagatgccg gatgtcatct ttgctggaac
    51841 agaaagtcgc aaaccgctca attatgcttc tgtagttgtg actctggata atcatgacgg
    51901 atttatcaag gatgcaggtc aagaaatcag ggtggaacgc catatctatc gtagtggaga
    51961 tagcgaatac aagattgacg gcaagaaagt ccgtctgcgt gatattcatg accttttctt
    52021 ggatacaggt ttgggacgag attccttctc tattatttcc caagggaagg ttgaggagat
    52081 ttttaattcc aagtctgagg aacgacgagc tatttttgaa gaagctgctg gagttttaaa
    52141 atacaagact cgcagaaaag aaaccgagag taaactgcag caaactcagg ataatctgga
    52201 ccgcttagag gacattatct acgagttgga taatcaaatc aagcctcttg agaagcaagc
    52261 tgagaatgcc cgtaaatttc tagacttaga aggtcaacgc aaggctattt acttggatgt
    52321 attggttgct caaatcaagg aaaataaggc agaactagag tcgacagaag aagagttggc
    52381 tcaggttcaa gaactcttga tgagttatta ccaaaagcgt gaaaaattag aagaagaaaa
    52441 tcaaactctt aaaaagcaac gccaagattt acaggctgaa atggccaaag accaaggcag
    52501 tttgatggac ttgactagtc tgattagtga tttagaaaga aaattagccc tatcgaaact
    52561 ggagtctgag caagtggcct tgaatcaaca ggaggcacaa gctcgtttgg ctgctttgga
    52621 ggataagaga aattcactca gcaaagaaaa gtctgataaa gaaagctctt tagctctgtt
    52681 agagggaaat ctagtccaaa ataatcaaaa actcaatcgt ttagaagctg aattgctggc
    52741 tttctcagac gatcctgatc agatgattga gctcttacgt gaacgctttg tagctctttt
    52801 acaagaagaa gcggatgtct caaaccagtt gacccgtatt gagaatgagt tggaaaatag
    52861 tcgtcagctt tctcaaaaac aagcagatca actagaaaag ctgaaagagc aattagctat
    52921 agctaaagag aaggctagtc agcaaaagga agagcttgaa actgccaagg agcaggttca
    52981 gaaattattg gctgactacc aagctattgc caaggagcaa gaggagcaga aaacttccta
    53041 tcaagctcaa caaagccaac tctttgaccg tctggataat ctcaaaaaca agcaggccag
    53101 agctcaaagt ttggaaaata tcctgagaaa tcatagtaac ttttatgcag gtgttaagag
    53161 tgttctccaa gaaaaagatc gcctaggtgg gattattggt gcagtcagtg agcatctgac
    53221 ctttgatatg cattatcaaa ctgccctaga aattgcgctt ggagcgagta gccaacatat
    53281 catcgtagaa gatgaagagt cggcaaccaa ggctattgac ttccttaaac ggaacagagc
    53341 cggtcgtgca acctttcttc ctttgaccac tatcaaggcg cgtacgattt ctagtcagaa
    53401 ccaagatgct atcactgtaa gcccaggttt ccttgggatg gcagatgagt tggtgacttt
    53461 tgatactaga ctggaagcca ttttcaagaa cttgctagct acgacggcta tctttgatgc
    53521 cgtagaacat gcgcgtgcag cagctcgcca agttcgttat caggttcgta tggtgacatt
    53581 ggatgggaca gaattacgca cgggtggttc ctatgcgggt ggtgccaatc gccaaaataa
    53641 cagtattttc atcaagccag aactggagca attacaaaaa gaaattgctg cagatgaagc
    53701 aagcttgcgt tcagaagaag cggctttgaa gaccttacaa gaccagatgg ctacattgac
    53761 agaaagatta gaagtcatca aatctcaagg agaacaggca cgtattcagg agcaaggctt
    53821 gtccctcgct tatcagcaaa ctagtcagca agttgaagaa ctggaaactc tttggaaact
    53881 ccaagaagag gaaatagatc gtctttccga gggagattgg caagcggata aggaaaaatg
    53941 ccaagatcgt cttgctgcaa tcgccagtga caagcaaaat ctggaagctg agattgaaga
    54001 gattaagtct aacaaaaatg ccatccaaga acgctatcaa aacttgcagg aagagctagc
    54061 gcaagctcgt ttgcttaaga cagaactgca agggcaaaaa cgttatgaag ttgctgatat
    54121 tgaacgctta ggcaaggaat tggacaatct tgattttgaa caagaggaaa tccagcgcct
    54181 tcttcaagaa aaggttgata atcttgagaa ggttgataca gaattgctca gtcaacaggc
    54241 ggaagaagcc aaaactcaga aaacaaatct ccaacaaggt ttgattcgca agcagtttga
    54301 gttggatgat attgaaggtc aactggatga tattgctagt catttggatc aggctcgcca
    54361 acagaatgaa gagtggattc gcaagcaaac acgtgctgaa gccaagaaag aaaaggtcag
    54421 cgagcgcttg cgctatttac aaagtcaatt aacagaccaa tatcagatta gctatactga
    54481 agctctagaa aaggcgcatg aattggaaaa cctcaatctg gcagagcaag aggtgcagga
    54541 tttagagaaa gctattcgct cactggggcc tgtcaatata gaagctattg accagtacga
    54601 agaagttcac aatcgtctgg atttcctaaa tagccaacga gatgatattt tgtcagcgaa
    54661 aaatctgctc cttgagacca ttacagagat gaatgatgag gtcaaagatc gctttaaatc
    54721 aacctttgag gccattcgtg aatcctttaa agtgaccttc aaacagatgt ttggaggagg
    54781 tcaggcagac ttaatcttga ctgagggaga cttgttgaca gctggggttg agatttctgt
    54841 tcaacctcca ggtaagaaaa tccagtcgct taacctcatg agtggtggtg aaaaagcctt
    54901 atcagctctt gctttgcttt tttctatcat tcgagttaag actatcccat ttgtcatctt
    54961 ggatgaggta gaggccgcgc tggacgaagc caatgttaaa cgttttgggg attacctcaa
    55021 tcgatttgac aaggacagcc agtttatcgt cgtaacccac cgtaagggaa ccatggcagc
    55081 ggctgattct atctatggag tgaccatgca agaatcgggg gtctcaaaaa ttgtttcggt
    55141 taagttaaaa gatttagaaa gtattgaagg atgacaatta aactagtagc aacggatatg
    55201 gacggaacct tcctagatgg gaatggacgc tttgatatgg atcgtctcaa gtctctcttg
    55261 gcttcctaca aggaaaaagg gatttacttt gcggtggctt cgggtcgggg atttctgtct
    55321 ctggaaaaat tatttgctgg tgttcgtgat gacattattt tcatcgcgga aaatggcagt
    55381 ttggtagagt atcaaggtca ggacttgtat gaagcgacta tgtctcgtga cttttatctg
    55441 gcaacttttg aaaagctgaa aacgtcacct tatgtagata tcaataaact gctcttgacg
    55501 ggtaagaagg gttcatatgt tctagatacg gttgatgaga cctatttgaa agtgagtcag
    55561 cattataatg aaaatatcca aaaagtagcg agtttggaag atatcacaga tgacattttc
    55621 aaatttacaa ccaacttcac agaagaaacg ctggaagctg gagaaacttg ggtaaacgat
    55681 aatgtccctg gtgtcaaggc tatgacaact ggctttgaat ctattgatat tgttctggac
    55741 tatgtcgata agggagtggc tattgttgaa ttagctaaaa aacttggtat cacaatggat
    55801 caggtcatgg cttttggaga caatcttaat gacttacata tgatgcaggt tgtgggacat
    55861 cctgtagctc ctgaaaatgc acgacctgaa attttagaat tagcaaagac tgtgattggt
    55921 caccataagg accagtcggt tatagcttat atggagggct tataatggca gatataaaat
    55981 taatcgcatt ggacttggat ggtaccttgc tgactactga taaaaggctg acggatcgca
    56041 ccaaggcaac tttgaaagct gcgagtgatc gtggtatcaa ggtcgtattg acaactggtc
    56101 gtcccttaaa agccatggac ttctttctcc atgagttagg gactgacggc catgaagatg
    56161 agtataccat tacttttaat ggtggattag ttcagaaaaa tacaggagaa atccttgata
    56221 aaacagtctt ttcatatgat gatgtggcac gtttgtatga ggaaacagag aaattatcac
    56281 tgcctcttga tgccatctca gaaggaacag tttatcaaat ccaatcggac caagaaagtc
    56341 tttatgccaa attcaatcca gctttgactt ttgttccagt tgactttgaa gacctgtcta
    56401 gtcaaatgac ctacaacaaa tgcgtgactg cctttgctca agaacccttg gatgcagcca
    56461 ttcagaagat ttctccagaa ttgtttgacc aatatgaaat ctttaaatca cgtgaaatgt
    56521 tgctagaatg gtcaccaaag aatgttcata aagcaacagg tttggcaaaa ctaattagcc
    56581 atcttggaat tgatcaaagt caagtgatgg cctgtggtga cgaggccaat gacctctcta
    56641 tgattgaatg ggcagggctc ggtgttgcca tgcaaaacgc tgttcctgaa gtaaaggcag
    56701 ccgcaaatgt agtgacgccg atgaccaacg atgaggaagc tgtcgcctgg gctatcgaag
    56761 aatatgtgct aaaggagaac taagatatgg gattatttga ccgtctattc ggaaaaaaag
    56821 aagaacctaa aatcgaagaa gttgtaaaag aagctctgga aaatcttgat ttgtctgaag
    56881 atgttgatcc taccttcaca gaagttgaag aagtttctca agaagaagct gtgcttgaag
    56941 aaagtcagga ttcagagcca gctgtagggg tttctcaaga agaaatagaa gaattaccag
    57001 aggaagagaa gcttgagcac gaaggaacta tagaagaaaa taattctgaa gttcttgaag
    57061 cagaaaggcc tcaaacagaa gaaactgttc aggaaaaata tgaccgcagt cttaagaaaa
    57121 ctcgcacagg tttcggtgcc cgcttgaatg ccttctttgc taacttccgc tctgttgacg
    57181 aagaattttt cgaggaactg gaagaactgt tgattatgag tgatgttggt gtccaagtcg
    57241 cttctaactt aacggaggaa ctacgttacg aagccaagct tgaaaatgcc aagaaacctg
    57301 atgcacttcg tcgtgtcatc attgagaaat tggttgagct ttatgaaaag gatggtagct
    57361 acgatgaaag catccacttc caagataact tgacagttat gctctttgtt ggtgtgaatg
    57421 gtgttgggaa aacaacttct atcggaaaac tagcccaccg ctacaaacga gctggtaaga
    57481 aggtcatgct ggttgcagca gataccttcc gtgcgggtgc agtagctcag ctagctgaat
    57541 ggggccgacg agtagatgtt ccagtagtaa ctggacctga aaaagctgat ccagccagcg
    57601 tggtctttga tggtatggaa cgtgccgtgg ctgaaggtat cgatattctc atgattgata
    57661 ctgctggtcg tctgcaaaat aaggataacc ttatgactga gttggaaaag attggtcgta
    57721 ttatcaaacg tgttgtgcca gaagcaccac atgaaacctt cttggcactt gatgcatcaa
    57781 caggtcaaaa tgccctagta caggccaaag aattttcgaa aatcacacct ttaacgggaa
    57841 ttgttttgac taagattgat ggaactgctc gaggaggtgt ggttctagcc attcgtgaag
    57901 aactcaatat tcctgtaaaa ttgattggtt ttggtgaaaa aatcgatgat attggagagt
    57961 ttaactcaga aaacttcatg aaaggtctct tggaaggttt aatctaatca gaagcaaaaa
    58021 tcctgcaagg cataaacttg caggaaattt ttttattcga aacgaccatc ttgacgatag
    58081 gcgatatctg gttgccaagt ccatttggca ccgaattttt caagtaggtc aaagctggct
    58141 tgaggtccca tgcttccagc tttatagtca tgaagtgggg caccattttc agcccagagc
    58201 tcttcaatac ggtcaatcaa cttccatgat gcaccaactt catcccagtg gctaaagtta
    58261 gttgagttgt tatttaggac atcataaatc aatttctcgt atggttctgg agaagcacca
    58321 gttgcagtcg catctgtacg gtaatcaagt gagttaggag ccaagttaaa ttcttctcct
    58381 acttgcttcc catttaggct aagagagaag ccttctgttg gttgaatata gatggtcaaa
    58441 atatttggag caagtggttc tccaaagata gaatccattt gtttaaagac gatgttgaca
    58501 tgagttcctt tttcagtcag tcgtttacct gtacggaaaa agaaaggaac actacggaat
    58561 cgatcgctgt ctacaaagaa ggcaccagat gtaaaggttt cagttgttga ttctggattc
    58621 acatttggct cgctacgata agagatgtat ttcatgccat caatcttacc agagcggtat
    58681 tgcccacgga taaagtgttc tttgagttct tcatcagttg gatgatagag gtttttaaag
    58741 accttaatct tttcagcacg aatctcgtct tttgtgaaga ttgctggttt gtccatggcg
    58801 aggagcgaaa gaagttgtag agtgtggttt tggaccatgt cacggagggc accggattgg
    58861 tcatagtagc caccacgttc ttctacaccc aagcgctccg caaaggtaat ttgaacattg
    58921 tcgataaaat ccttgttcca aacgttttca aaaatcaagt ttgcaaagcg aactgcaaag
    58981 atgctttgga tcatttcctt accaagataa tggtcgatac ggaaaatttg ttcttcgtca
    59041 aatgttgcta ggagttcgtc attcaacttg cttgcagttg cgtaatctgt accaaatggt
    59101 ttttcaacga tcaagcgctc aaaacctttg ccatcgacaa tgttttcaga tttgaggtgt
    59161 ttggcaatgg ttccaaagaa ctgaggtgcc atagacaaga agaagagctt attgtgttca
    59221 gcttggtatt tttcattaag ctcagcttgt aattgacgca aagcaatata atgttccgaa
    59281 tcattgacat catggctttg atagtagaag tggctagcaa attcttgggc ttgctcggta
    59341 ctatctgcca aatcaaggat ggactcgaca actacagatt caaaatattc cttactccaa
    59401 ggtctacggg cagttccaat aacggcaaag tgcttggaaa gattgccgga ttgatatagt
    59461 ctaaaaaggg aagggtagag cttgcgttta gccaggtctc cactcgcacc gaaaattgta
    59521 acaataacct tagatgacat ctagctacct aatttctatt tttattccta gtcttgctag
    59581 gtatgaggaa acctcatttc ataaacttaa ttctaacata attttccgaa aaatcaaaaa
    59641 ttccaatacg aggtagaaaa actgcaagga aatccttaca gtttgagttt agacgtttaa
    59701 gaccttatct aagaactctt tcagacgagg gtgttgtggg ttatcaaaga tttggtcagg
    59761 tgttccgtct tcaaggaact cgccatctgc agtaaagata acgcggttgg caacctgacg
    59821 agcaaatccc atctcatggg ttacgataat catggtcatg ccttgctcag ccaattcctt
    59881 cataacgtta agtacgtctc caaccatctc agggtcaagg gcagaagttg gttcatcgaa
    59941 gagcatgatg tctggattca ttgctaggcc acgagcgatg gccacacgtt gtttttgacc
    60001 acctgatagg ttatctggat tggcattagc tttatctgct agtccaacct tttcaagcaa
    60061 ctccattccc aattcctcag cttcttcctt agtcatcaac ttgtgctcaa taggagcaaa
    60121 ggtgatgttg tccaatacag acatatgagg gaagaggttg aagtgttgga ataccatgcc
    60181 gatattttca cggacgtggt caacattggt tgttttttca gttaaatcat agccgttcac
    60241 agtgatgtga ccgctagtga cttcttctaa aagattgagg ctacggagga aagttgactt
    60301 accagaacct gaaggaccga tgatacaaac aacatctcct tcatagaact tagtcgtaat
    60361 tccttttagg acttcatttt ttccatagtg cttgtgtaaa tcatttacat caatttttaa
    60421 ttttgccatt aacgaatcct cttttctaag cgtttcgcta gtctagtcaa aagtgtgata
    60481 attacaagat agaagatagc aaggattgca tacatcttga aactttggta gttacgagca
    60541 atgataatct taccagtttg gaagagttca accaaaccga tagcagatac gatagttgta
    60601 tctttaagag cgataacgaa ttggttgaca aagtttggca acatcaattt agttgcttgt
    60661 ggcaagataa tcttacgcat ggtttttcca taagagatac ccaagcttcg gctggcttcc
    60721 atttggccaa ctggaacggc ctgaatacca ccacgaacga tttcagcgat ataagcagcc
    60781 gcattgagtg agagggcaat ggttccagct acaaagtcgt taattgggct ttgttggcct
    60841 gtgatagact cgatgaagtt tggaattccc cagaagatga aggctgcaag aatcatcaat
    60901 ggaataccac gaataacgtc aacgaaaatc tcagagatga cgcgaagaga tttgtatggg
    60961 ctaacgctaa acataccgaa gataattccg atgacaatgg caatagcaaa tgagataaga
    61021 gctagagcaa gagtgatacc aagaccgcta aggagttgtt tgtagttgtt ttgaagcaag
    61081 ccccagagcg ttgtttcgtc aacagtactt gttgaagcag ttgaagattc gctagctagg
    61141 tatttgtcaa gaatcttttg gaattcaccg tttgctttaa ggtttgcaag tccgttgttg
    61201 aacatttcaa tcagttctgg atttgctcct tttttaacgg caaaggctgt ttcaccgatt
    61261 ggagttccag agattggagt tttcaatttt tgaccttggc tgatagaata tttgagaaca
    61321 ggttcatcat ccataacggc atcaatggca ccagtgttta aactgtcata cattgaagaa
    61381 ccatcagcaa aggttttgat tttgtaaccg tatttgcttt gattttctgt taggaaggtt
    61441 tgagaagcag ttccgttttt aacaccgact gtctttcctt ttagatcttc ataagaagca
    61501 atattgcttg attctttgac accaagaatg gtattagcag tgtagtatga ttctgagaag
    61561 tcaaaagttg ccttacgagc atctgtgaca gacataccag caatgatacc atcggcttga
    61621 ccagcttgga cagcactgat agcagcatca aaaccagggt tggtgatttc aatttcaaaa
    61681 ccttggtctt tagcgattgc cttaatcaat tccatatcaa taccagtgta ttggttgctt
    61741 gaattttgga aaacaaaagg tgcaaaagaa gaatcgctgg caatgatata tttagcctta
    61801 acaggaatag cttttaatcc tgcgagagta gttgtagttg gcactgctga agatgatgaa
    61861 gcagtccatt tcttgataat tttatcaaga ctaccatctt ttttcatttc agccaaggct
    61921 tggttaaatt cagtaaccag gtgctcgtat ttacttcctt ttttcacacc gaaagcaaaa
    61981 cttcctacag cttcaccatc catttcaata tggaggtctt gaccttggtt aatggcatat
    62041 tcgataacag gtttgtcatc catcatggca tcgatggcac cagcactcaa gctgttgttc
    62101 attaaatcac cagtgtcaaa tgttttaata gtaaagccgt atttatcttt gattgtttca
    62161 aggaaacgtt gagcggcagt tccgttttta acaccaacgg ttttgccagt taattggtcg
    62221 tacttgctaa ttttgtgtga ctttgtagta gcaatgacaa cttttgtatc atagtaagta
    62281 tcagacatgg tgaagacttt ttcacgttct ttagtctttg tcatccctgc catgatagcg
    62341 tcggcttgcc cagcttgaac cgcattgact gctgcgtcaa atccaggata ggacatctga
    62401 atgttccagc ctttaatctc agcgactttg ttaataatgt caacatcaat tcctttataa
    62461 gtttgatctg aatctttaaa ctcaaaaggt gcataggcgg tatcagaaac aatcttaatc
    62521 gtttctgctt tggcaatacc taatgagaaa attgggaata aaattagcaa aaatgctaga
    62581 aattttttct tcatttttag tctccttttc cgaatattct ctcattatat cagaaaaagt
    62641 aaaaaaaggc aaatttttat atttttcgtg tcagaaaata taacattgat ttttcctttt
    62701 ctttcttgaa ttgctattaa aaattgctat aataatacta tatatagaag aaaagaggac
    62761 ggggatatga agaacaaaag aatatttaaa gacttccaag cttcaaaaat gaatttaaac
    62821 ctttacacaa gccccttgtt agcctttgtt tttgtcttca taggagagtt tgtggcttat
    62881 actttatatg gtattagttt gttagctctc atcggacttg ctagaaattt tggagaggct
    62941 ggtcaaaatc ttgcaagcta cttgcagacc ttgcatcaga gcttgacgga taaaacaagt
    63001 gactttcgtt taattttagg attactggcc tttggtttta ttcttaacac tgtgttcaga
    63061 tggacaagaa aagttgagaa aagacctatt cgaaccttgg gattttatag agagaattgc
    63121 ctcagcaatc ttctgaaagg atttagtcta ggcctggcac tttttcttct gaccttgtta
    63181 agtttagtgg tcttaggtca atatcgtttg gaatccattc acttgaatcc ttattatctt
    63241 gcctttgtcg tctttactat cccattttgg attttacagg ggacagcaga agaagtggtg
    63301 gcccgtgctt ggctacttcc tcaattggcc tcaagaacca atctaaaact agctattctt
    63361 atatctagcc tgttctttac cctgcttcat atgggcaatt ctggcctcac ccctctatct
    63421 ctagtaaatc tctttttatt cggagttgcc atggctcttt accttctcaa aactgataca
    63481 gtttggggtg ttgcaggtat tcatggtgct tggaattttg ctcagggtaa tctctttggg
    63541 attttagtta gtggtcaacc gtcaggaacg tctctgatga cctttttacc acaaggcaat
    63601 caagattggc tatcaggtgg ttcttttggc atagaaggtt ccattatgac aagtctggta
    63661 ttactactgc tgattgtcta tcttgctaat aaattaaaga aagaaaatga aaggatgtga
    63721 cttcggtccg tccttttctt cgtgaaaata ctataagtat gctaaaatag gaatagcaca
    63781 tggagagagg attcttatga tcaatcacat tacagataat caatttaaac tagtatcaaa
    63841 atatcaacca tcaggagatc aaccccaagc tatcgagcag ttggtggata acattgaggg
    63901 gggagaaaaa gctcagattc tgatgggggc gactggaaca gggaagacct atactatgag
    63961 tcaggtcatt tctaaagtca ataaaccaac tctggttatt gcccacaata aaactctggc
    64021 tggtcagctc tatggggagt ttaaggaatt tttccctgaa aatgcagttg agtatttcgt
    64081 atcctactat gattattacc agccagaggc ctatgtccct tctagcgata cctatattga
    64141 gaaggatagt tctgtcaatg acgagattga caagcttcgc cactcagcta cctcagccct
    64201 tttggagcgt aatgatgtta ttgtcgtggc ctcagtctct tgtatctatg gtttgggttc
    64261 gcccaaggaa tacgctgata gtgtcgttag tctccgtcct ggtctagaga tttctcgtga
    64321 taaactcttg aatgacttgg tcgatattca gtttgaacgc aatgatattg atttccaacg
    64381 cggaagattt cgcgttcgtg gggatgtggt agagattttc ccagcttccc gagatgaaca
    64441 tgcctttcga gtagaatttt ttggagacga aattgaccgt attcgtgaag ttgaggctct
    64501 gacaggtcag gtgttgggag aagtggatca tttagcgatt ttcccagcga cacactttgt
    64561 gaccaatgac gaccacatgg aagttgccat tgcaaagatt caggccgagt tggaagaaca
    64621 attagctgtc tttgaaaagg aaggtaaact gcttgaagcc cagcgtttga aacagcggac
    64681 agagtatgat atcgaaatgt tgcgtgagat gggctatacc aatggggttg aaaattattc
    64741 tcgccacatg gatggacgga gcgaaggaga gcctccttat acgcttctcg acttcttccc
    64801 agatgatttc ttgattatga ttgacgagag tcatatgacc atagggcaaa tcaagggcat
    64861 gtacaatgga gaccgttcgc gtaaagaaat gctggttaat tatggtttcc gtttgccgtc
    64921 tgctttggac aatcgtcctc tccgtcggga ggagtttgag agtcacgttc atcagattgt
    64981 ttacgtttca gcgacacctg gtgactatga aaatgaacag accgagacag tgattgagca
    65041 aatcattcgt ccaacgggac tcttggatcc agaggtggaa gtccgtccga ctatgggaca
    65101 gattgatgac ctcttgggtg aaatcaatgc ccgcgttgaa aaaaatgagc gtacctttat
    65161 cacaactttg accaagaaaa tggcagagga cttgaccgac tacttcaagg aaatgggtat
    65221 caaggttaag tacatgcact cggatatcaa gaccttggaa cggacggaga ttatccgtga
    65281 cctgcgcttg ggtgtctttg atgtcttggt cggaattaac ctgctccgtg aaggaattga
    65341 cgttcctgaa gtgagcctcg tagctattct cgatgctgac aaggaaggtt tccttcgcaa
    65401 cgaacgtgga ctcatccaga ctattggacg tgctgctcgt aacagtgaag gccatgtcat
    65461 catgtatgca gacacggtta cccagtctat gcaacgtgct atcgatgaaa ctgcccgccg
    65521 tcggaaaatt cagatggcct ataatgaaga gcatggtatc gtaccacaga caatcaagaa
    65581 agaaatccgt gacctgattg ctgtgaccaa ggcagttgct aaggaagagg acaaggaagt
    65641 cgacatcaat agcctcaaca aacaagagcg caaagaactc gtcaagaaac tagaaaaaca
    65701 aatgcaagaa gccgtcgaag tacttgactt tgaactggcg gctcagatcc gtgatatgat
    65761 gttggaagtc aaggccttgg attaggggaa tagtatgatt tatttaagaa agttaaagag
    65821 agaagatttg atgtctttat gggaaatggc ttattcacaa cttaatccag tttggaaaca
    65881 gtatgatgct ccctattatg atgattatca gtatttttca aattttaaag aattcgaact
    65941 acaaaaatca gaatccattt taagcaactc aaatcgcctt ggtatttttg ttgatgataa
    66001 actagttggg actgtttcgc gttattgggt atgtaaacaa acaagatgga tggaattggg
    66061 aattggtatt tatgataaaa aattctggaa cactggtatt gggaaagttg ctatgttgca
    66121 gtggatagat aggacgtttc aggattactt ggagttggag catctgggtt tgacaacttg
    66181 gtcagggaat cttggtatga tgaaacttgc tgaaaaatta agaatgaaaa aagaagctca
    66241 tattccaaaa gttcgttatt atcaaggtaa atattttgat agtattaaat atggtatttt
    66301 gagagaagac tgggagaaaa caaatgacgg ttattatcaa atcaatggaa actcctgaag
    66361 agatagaagg taagcccctt gttcactggc aaacgtggag agaggcttat gatggccttt
    66421 tgcctgcaga atttcaggag acaatgacat tagaaagatg tcgattcttt agtcaaaagt
    66481 atccagaaaa tacattgatt gcgatggatg gtatgaaggt agttggtttt atcagttatg
    66541 gcaactttcg tgatgagact attcaagctg gcgaaattat tgctttatat gttttaaaag
    66601 actattatgg aaaaggtatc gcacaaaagt taataaaagc agctttgatt gctcttaatc
    66661 atttttctga aattttctta tgggtattga aagataataa gcgcgcaatt gctttctatc
    66721 aaaaaatggg ctttactttt gatgaacaag aaaagatact tgaacttgga aagcccataa
    66781 aggaaaaacg gatggtattc tattctaaat aattttaaaa agtagaagct aatggtactg
    66841 gtatcaagtc taaaaattta ataaattaga aagtgagtaa atttatgtct cgagcacaat
    66901 taacgatttt aacaaatatt tgtctgattg aagatctcga agctcagcgc gtggtgatgc
    66961 agtatcgcgc tcctgaaact aatcgctggt ctggttatgc ctttccagga ggccatgtag
    67021 aaaatggcga atctttcgca gagtctgtca ttcgtgaaat ctatgaagaa acagggttga
    67081 ctatccaaaa tcctcaactt gtcggcatta aaaattggcc actagataca ggtgggcgct
    67141 atattgtcgt ttgttataag gcaactgagt tctctggtac ccttcgctct tcagatgaag
    67201 gagaagtttc ttgggtgcaa aaagaccaga ttccaaactt ggatctggcc tatgatatgc
    67261 tacctttgat ggagatgatg gaagcatcgg acaaatctga atttttctac cctcgccgta
    67321 cagaagacga ttgggaaaag aaaattttct aatcctttac taaataacct agctgatcca
    67381 aggcctcctc gatatagtgg aggtcttgtt gtgtttcggc ttcgactagg tggtaatgga
    67441 caccatctgt caattcagat aaaggtttaa aatcagaatg ctcgacttgt tctagaaaat
    67501 gttgaacgtc tcggcggcaa gacagtttaa gcaaggtttc aatttctcca taaacgggat
    67561 ggtcaatcaa agtattctgg acatgcccac cattatcgac aatagcaagg agttcctgac
    67621 cgatttcttc aacttcatgt ttcactttga aaagtttgtg aacataagga ttggtatcaa
    67681 tttgcttata gatgtagcca cgattggtgg ataggatagg agcgccatcg gctctcaaaa
    67741 ttgcaatgtc ctgcacaatg acctgacgtg tgacatgaaa atgttccgcc aaactttggc
    67801 cattaagggc tttaggagct tctttcaaga gttggagcag ggcttgtttg cgatcttttg
    67861 tcatagcttt tccttttaac ggcgttttcg aagcacttta tagacagcta gtgctaatgt
    67921 atagtctacc atactatgga taattgtgcc aaatccaact agtacaaata gaacatagaa
    67981 catgttttct acattggtac ccgaagttgc gtaaaaaagg acacaggcta atacttcagc
    68041 aagggcatga acaacagcca aaacaaaatt gaaaacccag gaagattttg gtttatctag
    68101 ggtatcgggg aatttttgta ggtaaagaga tcctaaagca ccaaaagata tatgggaaaa
    68161 agcccgaaaa actataacca tgggatagcc agccatcaaa aatccaaaac tagaggctag
    68221 gatgacaaaa actgccatca agggcgacaa gaacatggct ataaaaatag cgatgtggct
    68281 ccccaaagta taggaagcag gtggaatgac aatcttgaaa ggcataacaa ttggaatcaa
    68341 aatcgcaata gccgttaaaa gggctgtcat tgtcataaat tgtgtctttt tccgtgtatt
    68401 cacaagaatc tcctttttaa ctgcatatac actagtatgg tacaataaac cagacaataa
    68461 agcaagaatt tacttgggtt tatagatcat tttttagtta aaagttatag tagatggaaa
    68521 ctagaatagt ccacctctac ttctaaaaca ttgttagcga tttgactgtc ctgatcgatt
    68581 tgtcctgttc ttatttcgtt ttactatagt aaagatttca ttaaaaagaa actgtataga
    68641 gcaaaatctc caccttcagg tttgaaagcg gagattgttt ttattttttc aaggtttgta
    68701 gtcgtggaac aatggctagg gttagaattg cagaaatgac caattcagca attgaatttg
    68761 ttgagataac ggttgccaga agaagttgga tatttccatt ataaacattt ccaaatagga
    68821 agaagattcc tccaaggaca aagatagtat ttgtcaagga accaagggct ccagctaaaa
    68881 tcagaccagt cttgtttttc atcagtttat agactaagta aggagttaaa ccaatcaaaa
    68941 tacgtgggac gatggcaatg atagctgagt agatgtttcc gtttggtacg aagggagaga
    69001 agaggtagct tgtcggtaga atcgtaatcg tgttaaccgt caagctaagt aatcccatca
    69061 aaaatccaag tgtaacccca actcgtggac cataaataat gctggcaata atgacaggaa
    69121 tatgaacaat ggtcggtttg attggaaatg gaaaaaggtt aaagataagt gagctcagaa
    69181 agtgtatcac gagcatggta gcaaaaaaga tagcaatggg tgcaatatta gagcgttttt
    69241 tcatcgatag tttcctttat tctttctaaa ataattgtga ggtcagctaa agctcctcgt
    69301 ccgtggtctc cacaagctag tagggattcc ttaggagcaa tcagctgata gccgtaggtt
    69361 tctaatgttt tcagattatt ctgagttact ggatggtcat acatttttgt attcatagca
    69421 ggagctatta gtttgggaat atgacttggt agggctagag ctgtactggt taccatgttg
    69481 tccgcaaatc cgtgagctag ttttgcaata gtgttagcag ttgcaggtac cacgataaat
    69541 aaatctgctt tttttccaag ttcgatatga ttgacctgat caggataggg ttccttcatg
    69601 acatccaagt ggacaggatt ctgtgagagt acctgtagtg tcaaaggttg gataaactct
    69661 gtagcagcct gagtcattaa gacagtgact tgatggcctt gtttttttag agaactgact
    69721 aaatctgccg acttataaga ggcgattgaa cccgttacag ccaagagaat gtttgccata
    69781 gttttccttt ctaagaatga taggcttgaa ttttttcaag gaggagttct gcaatttctt
    69841 ctttagtctg gactgtttga agctgatttt tctcaacaaa tatagctcgg tgctgatctg
    69901 ctgaaatttg agtcaggtca ttcgcgatga ttaaatctgc ttgattcttg ataagacttt
    69961 ttcgtgcaat gtcaaccaga tgatcttcgg taacatcaac cagcagtttg aaaccaatca
    70021 gatgaatagt gggattccat tccttgacta gggatatgat tttgggtgtc tttttaagga
    70081 acaaaacctg aacctcatca gttgaagaaa tcttggcctg atgattctgc ttgcttaaaa
    70141 attcttttag attggagcta gcctgaactt cctcaagccc tgtcatataa acaggagtgt
    70201 agtcagaaac agccattgag tggatcaaga cctgataatc ctgaacacgt tcttgcattt
    70261 ctattagaag gtccttggta ttggtaattt ctcgaatact taggttagga tgaggctctg
    70321 gcttcagagc tcgttttgtc gtaattaaac aaacttcatg ccctgcagaa agcaaagtct
    70381 ctgtgataat tttccccaag tgacctgtag aatggttagt gatagagcgg acgctatcga
    70441 tagcttcact ggtaccgccc gatgtaacta aaattttcat agcactattg tacacaaaaa
    70501 taagcggtaa gtaaaatgaa agtgataaat ttttggtaaa aacgaagatt tactatagtt
    70561 tcaaactata aagccatata aaatttaaga aaggactcta aaagccttaa aaacagagat
    70621 atttacgaac gtttagagag ttttaggatg ttaaaaatct tgttttgtga tataatgaat
    70681 tatcatataa gaggttagag gaattttgaa tgaaaacaga tattgaaatc gcacagagta
    70741 ttgagttgaa gccaattgtt gatgttgtag agaaacttgg tatttcttat gacgatttgg
    70801 agttgtacgg aaagtacaag gctaaactca gctttgataa aattcgtgca gttgagagca
    70861 atccagtcgg taaattgatc ttggttactg ccatcaaccc aacacctgca ggtgaaggaa
    70921 agtcgacgct taccattggt cttgcggatg ccttgaacaa gattggcaag aaaaccatga
    70981 ttgctatccg cgaaccgtct cttggtccag tcatggggat caagggtggt gctgctggtg
    71041 gtgggtatgc acaagttctg ccaatggaag acatcaacct ccactttact ggagatatgc
    71101 atgctattac aactgccaac aatgcccttt ctgccttgat tgacaaccac ttgcaccaag
    71161 ggaatgagct ggaaattgat caacgtcgta tcctctggaa acgcgttgtg gacttgaacg
    71221 accgtgcgct ccgccatgtg actgttggtc ttggtggtcc tctaaacggt attccacgtg
    71281 aggatggttt tgatattaca gttgcttcag aaatcatggc aattctttgc ttggcaacgg
    71341 acatcgagga cttgaaacgt cgtttggcga atatcgttat tggttatcgc tatgaccgta
    71401 cgcctgtttc tgtaggtgat ttgcaggttg agggtgcctt ggctttgatt ttgaaggatg
    71461 ctattaagcc aaacttggtt cagacaattt acggtacacc tgcctttgta cacggtggtc
    71521 catttgccaa tatcgctcat ggctgtaact ctgttttggc gacgacaaca gcccttcact
    71581 tggctgatta cactgttact gaagctggtt ttggtgcgga ccttggtgct gagaaattcc
    71641 ttgatatcaa gacaccaaac ttgccaacat ctccagatgc agttgtcatt gtcgcaaccc
    71701 ttcgtgccct taagatgaat ggtggtgtgg ctaaagacgc tctgactgaa gaaaatgtag
    71761 aggcagttcg tgcaggtttt gctaacttga aacgccacgt tgaaaatatc cgtaagttcg
    71821 gtattccagc agttgtagct attaacgaat ttgtatctga tacagaagct gaaattgcag
    71881 tcttaaaaga actctgtgcc tcaatcgatg taccagttga attggctagt gtctgggctg
    71941 atggagcaga aggtggagta gcacttgccg aaacagttgt taagacaatt gctgaaaatc
    72001 cagctaacta taaacgtttg tacgataatg ccctttctgt ccaagaaaag attgaaaaaa
    72061 ttgtcactga aatctatcgt ggtagcaaag tgaactttga gaagaaagct caaacacaaa
    72121 ttgctcaaat cgttcaaaac ggttgggaca aattgccaat ctgtatggct aaaactcaat
    72181 acagtttctc agacaatcca aatgcgcttg gagcaccaga aaactttgaa attaccattc
    72241 gtgaattggt accaaaatta ggtgcaggct tcatcgttgc cttaactggt gatgttatga
    72301 ccatgccagg tcttccaaaa cgtccagcag ctctcaacat ggatgttgaa agcgatggaa
    72361 ctgtactagg cttgttctag tggattgaaa ttgactttaa gtgagtttgg aaataatatc
    72421 caagctcatt ttttctcaga ctgcaagcag ttcatcaata agatttatac tcttcgaaaa
    72481 tctcttcaaa ctacgtcagc ttcaccttgc cgtaggtata tgatactgac tctgtcagtt
    72541 ctatccacaa cctcaaaaca gtgttttgag caacctgcgg ctagcttcct agtttgctct
    72601 ttgattttca ttgagtataa gtagatagaa aagttatata ctatctattg aaaatattat
    72661 aaatcagata caaagacagg tgaaaccttc tgtgttatac tagagatatg ttagatttga
    72721 aagaatacgg tatcgtcatg tggccggagg agaaagtcat ttctttccgt gagaaacttc
    72781 tcgcttggta tgatgaaaac aaaagagatt tgccttggag gagaagtaaa aatccttatc
    72841 acatctgggt atctgaaatc atgcttcagc agaccagggt ggatacagtt atcccttact
    72901 acgaaagatt cctggactgg tttccaactg tcgaaagtct ggcaactgcg cctgaggaga
    72961 gtttactgaa agcttgggag ggcttgggct attattctcg agttcgcaat atgcaggctg
    73021 cagcccagca gattatgact gactttggtg gccaatttcc aaatacctat gaaggaattt
    73081 ccagcttgaa agggattgga ccttacacag caggagccat ttccagtatt gcttttaact
    73141 tgcctgagcc agctgtagat ggtaatgtca tgcgggtctt ggcgcgtctg tttgaagtca
    73201 accacgatat tgggattcca agtaatcgaa aaatttttca ggcaatgatg gagatcttga
    73261 ttaatccgga tcgtccgggt gattttaatc aagccttgat ggacttaggg tctgatattg
    73321 agtctcctgt aaatcccaga cctgaagaaa gcccagtcaa ggactttagt gcggcatatc
    73381 agaatggaac catggaccgt tatccaatta aatctcctaa gaaaaagccg gttcctattt
    73441 atcttaaagc attagttgtg aaaaattctc aaggacaatt tttacttgaa aaaaatgaaa
    73501 gcgaaaagct cttggcaggt ttttggcatt tcccccttat agaagttgat aacttttcgc
    73561 aagaagagca gtttgacctc tttcatcagg ttgcggaaga aagtgtgaac tttggcccca
    73621 gtccagaaga gagtttccag caggactatg acctagatgt tgattggctt gatgtttgtt
    73681 ttgatacagt ccagcatgtt tttagtcatc gaaaatggca tgtacagatt gtagcaggtc
    73741 aggtgagtga cttccatgat ttttcagata gggaagttcg ttggctttca ccagaagaat
    73801 tcaagaatta cccacttgcc aaaccccaac aaaaaatctg gcaggcttat gcacaagcca
    73861 acttagacag tagccaagac tagctattgt gtcttctgac tattttttgg tataatagta
    73921 gagaaaaagg tgaacatatg aaaaaaatac taattgtaga tgatgagaaa ccaatctcgg
    73981 atattatcaa gtttaatatg accaaggaag gttacgaagt tgtaactgct tttaatggtc
    74041 gtgaagcgct agagcaattt gaagcagagc aaccagatat tattattctg gatttgatgc
    74101 ttccagaaat tgatggttta gaagttgcta agaccattcg taagacaagc agtgtgccca
    74161 ttcttatgct ttcagccaaa gatagtgaat ttgataaggt tatcggtttg gaacttgggg
    74221 cagatgacta tgtaacgaaa cccttctcca atcgtgagtt gcaggcgcgt gttaaagctc
    74281 ttctgcgtcg ttctcaacct atgccagtag atggtcagga agcagatagt aaacctcaac
    74341 ctatccaaat tggggattta gaaattgttc cagacgccta cgtggctaaa aaatatggcg
    74401 aagaactaga cttaacccat cgtgaatttg agcttttgta tcatttagca tcgcatacag
    74461 gtcaagtcat cacgcgcgaa cacttgcttg agactgtctg gggttatgac tattttggtg
    74521 atgtccgtac agttgatgtg actgtacgac gtctgcgtga gaagattgaa gatacgccca
    74581 gccgaccaga gtatatcttg acgcgccgtg gtgtagggta ttacatgaga aataatgctt
    74641 gatttactga aacaaaccat ttttaccaga gattttatct ttatcctgat tttgttaggt
    74701 ttcatccttg ttgtgaccct cttattactg gaaaatagac gtgataatat tcagttgaag
    74761 caaatcaatc aaaaggttaa agatttgatt gcaggagatt attccaaggt tcttgatatg
    74821 caaggtgggt ctgaaatcac caatattacc aataatttga atgacttgtc ggaggttatt
    74881 cgtctcactc aggaaaatct agaacaagag agtaagaggc taaatagtat tctgttttat
    74941 atgacagatg gggttcttgc gaccaaccgt cggggtcaga ttatcatgat taacgataca
    75001 gccaagaagc aactggggtt ggttaaggaa gatgttctga atagaagcat tttggaattg
    75061 ctcaagatag aagaaaacta tgaattgcgt gatttgatta cccaaagtcc agaattgttg
    75121 ctagattccc aagatatcaa tggcgaatat ttgaaccttc gagttcgctt tgccttgata
    75181 cgtcgagagt ctggctttat ttcaggtttg gtggctgttt tgcatgatac gacggagcag
    75241 gagaaggaag aacgcgaacg aagactcttt gtttccaatg ttagccatga gttacggact
    75301 cctctgacta gcgtaaaatc ctatcttgaa gccttggatg agggggcttt gtgtgaaact
    75361 gtagcaccag actttatcaa ggtttctctt gatgagacca accgtatgat gcgcatggtg
    75421 acggatctcc tccatctttc acgtattgat aatgctacca gtcacctaga tgtggaactg
    75481 attaacttca ctgcttttat tacctttatc ctcaatcgtt ttgacaagat gaaaggacag
    75541 gaaaaggaga aaaaatatga gttggtgaga gattatccca tcaattctat ctggatggaa
    75601 attgatacag ataagatgac gcaggttgtc gacaatattt taaataatgc tattaagtat
    75661 tcgccagatg ggggtaaaat cactgtcaga atgaagacaa ctgaagacca gatgatttta
    75721 tccatttctg accacggttt ggggattcct aagcaggatt taccacgtat ctttgaccgt
    75781 ttctatcgtg tggatcgtgc tagaagtcgt gcacaaggtg gtacaggtct aggactgtct
    75841 atcgctaaag aaattatcaa acaacataag ggctttattt gggccaagag tgaatacggc
    75901 aagggttcaa cctttaccat tgtgctccct tatgataagg atgcagtgaa agaagaagta
    75961 tgggaggatg aagtagaaga ctagaatgag tgaaataggc tttaaataca gtattttagc
    76021 gtcgggttcc agtggaaatt ctttttatct ggaaacctca aaaaagaagc ttttagtaga
    76081 tgcaggcttg tctggcaaga aaattaccag tctgctagct gaaattaacc gtaagccaga
    76141 agacctggat gccatcttga ttacccatga gcattcagat catatccatg gagtaggcgt
    76201 tttggctcgc aagtatggta tggatcttta tgccaatgaa aagacctggc aagctatgga
    76261 aaatagtaaa tatcttggca aggtggattc ttcgcaaaag catatttttg aaatgggtaa
    76321 aaccaaaacc tttggagata tcgacatcga gagttttggt gtaagccatg atgcagtcgc
    76381 accgcagttc tatcgcttta tgaaggatga taagagtttt gtcctcttga cagatacagg
    76441 ttatgtcagt gaccgtatgg cgggcattgt cgaaaatgcg gatggttatc ttatcgaggc
    76501 caaccatgat gtagagattt tgcgatcagg ttcttacgct tggcgcctca aacaacgaat
    76561 cctatctgac cttggtcacc tttctaacga ggacggtgct gaagctatga ttcggacgct
    76621 aggaaatcgt actaagaaga tttaccttgg gcatttatct aaggaaaaca atatcaagga
    76681 actggctcat atgaccatgg tcaatcagct ggctcaagct gatctgggag tcggagtaga
    76741 ctttaaggtt tatgatacct caccagatac cgcaacacca ttgacagaga tatagaaaga
    76801 acgctgagaa ggtgttcttt ttatattgac tggacaccta aaaagtaata caatggtgtt
    76861 accattaaaa aagggagcac aaaagatgac tactattaca ttaaaagttt ctgaagctga
    76921 taaaacattt atgaaagcaa tggctaagtt tgaaggagtt tccctttcgg aacttattcg
    76981 caccaaaact cttgaagccc tagaagatga atacgatgct cgtgtggcag atttagccta
    77041 tcaagagtat ttagaagact tggaaaaagg agttgaaccc attacttggg aagaaatgat
    77101 gcatgattta ggcttgaagg atgaataatt tgtataaatt agttccaaca agacgtttta
    77161 tcaagcaatt gaaaaaattg gaccgttata cgcagaagct aattacaaac tatttacaaa
    77221 ccaatgtttt ggaagatcca agacgacacg gaaaggcttt ggttggtaat cgcgttggtc
    77281 aatggcgcta tagaattggt aattatcgag ttatcgtaca aattgtagat gatgaattag
    77341 ttgttgctac tctagaagtt ggtcatcgga gagatattta ttaaattaaa gctgagtaat
    77401 aacagtatag aaagtaagga gagtaaaaat ttgaagaaaa aatggttttt tgcagattat
    77461 tatgacacaa caattatttt acttgcttta atctctgtta ttctggtatt acttggattt
    77521 gctgagatga ttgatttgga caatccgcct tatagtatta ttgatttagt aatctggggt
    77581 gtttttgtaa ttgattatag ttggcgcttt tttacgacta aaagaaaatg gcgctttatt
    77641 cttgaaaata tttttgattt attggctatt ctccctttaa atgctatttt tacagtgttt
    77701 cgattagggc gtatctttcg tttagctaaa ctaacaaaat tactgaaact gactcgttta
    77761 cttagaataa ttggacttac aggtaaatta gaaagaaaaa ttagtagatt cttacggaca
    77821 aatggcctga tttatatctt gtatgttaat atctttattg ttctagtagg gagttcgatt
    77881 ttatccgttg ttgaagaaaa atccttctca gatagtcttt ggtgggctct tgtgacagta
    77941 actactgttg gatatgggga tattgttcct gcttccattt ttgggaaatg gctagcagtt
    78001 ttactgatgc ttgtcggtat tggaacaata gggatgttaa caagtgcttt gacgaacttt
    78061 tttgtaaagg ataatccaga tgaacagata aaacttgata aactcaaaga tgaattatcg
    78121 agccaaagaa tattactaga gaaacaatct aaaaagatag aagaactaca taaaatgata
    78181 caagatttga ttgaaaaaac ataataaaaa taaagatgag acaaagtttg agctgaggag
    78241 aaatcaagta agttttgaca caatagaacg catattatca ggtataaaaa cttgatacta
    78301 tgcgttttat agagaaataa aataaaatct gaacaaatca attaggaatt taaagcattt
    78361 tataacaacg ttttagagtg atggggtgct atttcaactt caacctacta taatacagaa
    78421 aaaaacaact ccctgatgat tcaaggagtt gtctatagtt aaattagttt ttagaagctt
    78481 cttggaattc tggatttttc catgcttcgt caataatagc ttgcaattct ttagcagatg
    78541 cttgcatttt ttgagtttct gcatcgttca atggaatgtt tactggacga acgataccat
    78601 gtgcaccaac aacagctggt tgaccgataa agacattctc aactccgtat agaccttctt
    78661 ggaatactga aagtggaagt actgcgtttt catcgtcaag gattgcttta gtgatacgag
    78721 caagggctac tgcgataccg tagtatgttg cacctttttt gttgatgatt gtgtaggctg
    78781 catcacgaac accttcgaac aattcaatca attcagcttc ttgaacattt tgagtgtctt
    78841 taaggaattc ttcaaggttt acaccagcga tgttagcgtg tgaccaaaca gcgaactcag
    78901 agtcaccgtg ttcacccatg atgtaggcgt gcactgaacg agcatccaca tccaattttt
    78961 cagcaagtgc ttgacggaaa cgagctgagt caagtgaagt acctgaaccg ataacgcgtt
    79021 ctttagggaa accagagaat ttccaagttg agtaagtcaa aacgtcaact gggttagcag
    79081 caacaaggaa gatacctttg aaaccagatt caacaacttg agttacgatt gatttgttga
    79141 tagcaaggtt tttacctaca aggtcaagac gagtttcacc tggtttttga ggtgcacctg
    79201 cagtaatcac aacaaggtca gcgtctgcac agtcagagta ttgagctgca tagatttttt
    79261 taggtgaagt gaaggcaagg gcgtgactaa ggtcaagcgc atcaccaaca gctttttcat
    79321 gcaattgtgg aatttcgata attccaagct cttgtgcaat tccttggtta acaagtgcaa
    79381 aagcgtaaga tgaacctaca gcaccatcac cgacaaggat aacttttttg tgttgtttag
    79441 ttgaagtcat tgttttaaac atctccttaa ttttattagg ggattttccc tagacaactt
    79501 cattctatca cttttaaaaa actttgtcac gaatatgcct tatagttctc gatgtaaacg
    79561 ttttagtggt ttagaggctg aaatagatgg gaatttatgg tataatgttg ttacttacta
    79621 attgtgaaat gaggcattta ttaatgcagg ataaaaattt agtgaatgtc aatctgacaa
    79681 aggagatgaa ggcaagtttt atcgactacg ccatgagtgt tatcgtagcg cgagctcttc
    79741 ctgatgttcg agatggctta aaacctgttc accgtcgcat tctctacgga atgaatgaat
    79801 tgggtgtgac cccagacaaa ccccataaaa aatctgctcg tattacaggg gatgtcatgg
    79861 gtaaatatca cccacacggg gattcctcta tttatgaagc catggtccgt atggctcaat
    79921 ggtggagcta ccgttacatg cttgtagatg gtcatgggaa ttttggttcc atggatggag
    79981 atagtgctgc cgctcaacgt tataccgagg cacgtatgag caagattgct ctggaaatgc
    80041 ttcgtgatat caacaaaaat acagttgatt tcgttgataa ctatgatgcc aatgaacggg
    80101 aacccttggt cttgccagcg cgttttccaa accttttggt taatggagca actggtatcg
    80161 cggttgggat ggcaaccaat attccacctc ataatctggg tgaaaccatt gatgcagtga
    80221 agttggtcat ggataatcct gaagtgacta ccaaggactt gatggaagtc ttgcctggac
    80281 cagattttcc aactggtgct cttgtcatgg ggaaatcagg tatccataag gcttatgaaa
    80341 caggtaaagg ttcgattgcc ctacgttctc gtacagagat tgaaacgact aagactggtc
    80401 gtgagcgcat cgttgtaaca gaatttcctt acatggtcaa taaaaccaag gtgcatgagc
    80461 atattgttcg cttggttcag gaaaaacgca ttgagggtat cacagcagta cgtgatgagt
    80521 caaaccgtga aggtgttcga tttgttattg aagtcaagcg cgacgcctca gccaatgtta
    80581 ttctcaataa cctcttcaaa atgacccaaa tgcaaaccaa ttttggtttc aatatgctcg
    80641 ctatccaaaa tggtataccg aaaattttgt ctcttcgtca gattttggat gcttatatcg
    80701 agcaccaaaa agaagtggtt gttcgtcgta cacgttttga taaggaaaaa gcggaagcgc
    80761 gcgctcatat cttagaaggt ctcttgattg cgctagacca tatcgacgaa gtgattcgta
    80821 tcatccgtgc tagtgaaacg gatgcggaag ctcaagctga gttgatgagc aagtttaagc
    80881 tttctgaacg tcaaagtcaa gctatccttg atatgcgtct tcgtcgtttg acaggtttgg
    80941 aacgcgataa gattcaatct gagtatgatg acctcttggc tctgattgcg gatttagcag
    81001 atattcttgc taagcctgaa cgtgtttctc aaattatcaa agacgaattg gatgaagtta
    81061 aacgtaaatt ttctgataag cgccgtacag agttgatgat tggacaggtc ttgagtctcg
    81121 aggatgagga cttgattgaa gaatcggatg tcttgattac cctttctaac agaggctaca
    81181 ttaagcgttt ggatcaggac gagttcactg ctcaaaaacg tgggggtcgt ggtgtccaag
    81241 gaacgggagt gaaagatgat gactttgttc gtgagttagt gtcaactagc acccatgatc
    81301 atctgctctt cttcacaaac aagggacgtg tctatcgtct taaaggttat gaaattcctg
    81361 agtatggtcg gactgccaaa gggctaccag tagtcaatct cttgaaattg gatgaagacg
    81421 aaagtattca gacggttatc aatgttgagt ctgatcgcag tgatgatgct tatctcttct
    81481 ttacaacccg tcacggtatt gtgaagagaa ccagtgttaa ggagtttgcc aatattcgtc
    81541 aaaatggtct caaagcgctg aatttaaagg atgaagatga gttaatcaat gtcttgttgg
    81601 cagaaggaga tatggatatt atcattggta ccaagtttgg ttatgcagtt cgctttaatc
    81661 aatcagccgt tcgtggtatg agtcgtatcg ccactggtgt gaaaggtgtt aaccttcgtg
    81721 aaggagacac agttgttggt gccagcttga ttactgatca agatgaggtt cttattatca
    81781 cagaaaaagg atatggtaag cgtacagtcg ctactgaata cccaacaaaa ggtcgtggtg
    81841 gtaagggaat gcagacagct aaaattaccg aaaaaaatgg cttgctggcc ggtcttatga
    81901 ctgttcaagg ggatgaggat ttgatgatta tcactgatac aggtgtcatg attcgaacca
    81961 atcttgccaa tatttcacaa acaggacgtg caactatggg agttaaagta atgcgcctgg
    82021 atcaagatgc tcagatagtg actttcacaa cggttgcggt ggcagaaaaa gaagaagttg
    82081 ggacagaaaa cgaaacagaa ggtgaagaat aatgtctcaa aaaaataata aaaagaaaaa
    82141 caagcgaaaa aatctgctga caaatatcct agcaggattt ctgatattac tgtcactggc
    82201 tttgattttt aatactcaaa ttcgaaatat tttcatagtc tggaatacca ataagtatca
    82261 agttagccag gtatcaaaag aaaaattaga agaaaatcag gatacagaag gcaattttga
    82321 ctttgattct gtcaaagcta tctcttcgga agctgttcta acttctcaat gggatgctca
    82381 aaaattacca gttattgggg gaattgcaat tcctgaattg gaaatgaatt tgccgatttt
    82441 taaaggactt gataatgtta atctcttcta cggagctggt acaatgaaac gcgagcaagt
    82501 aatgggagaa ggaaattata gtctagctag tcaccatatc tttggtgttg ataatgctaa
    82561 taaaatgtta ttttctcctt tagataatgc taaaaatggc atgaagattt atctaaccga
    82621 taaaaataaa gtttatactt atgaaatacg tgaagtcaaa cgtgtgacac cggatcgtgt
    82681 tgatgaagtt gatgatagag atggggtcaa tgaaatcaca ttagtaacct gtgaagacct
    82741 tgctgctaca gaacgtatta ttgtcaaagg tgatttgaaa gaaacaaaag attattcaca
    82801 aacatctgat gaaattctaa cagctttcaa tcaaccatat aaacaatttt attaatacaa
    82861 atcagtgaaa tcatggattt cactgatttt ttaagatttt cataaaaata tagtaaaatg
    82921 aaataagaat aggacgaatc gttcaggaca gtcaaatcga tttctaacaa tgttttagaa
    82981 gtagaggtgt actattctag tttcaatcta ctataaactt ttatgaaata cagaaaacgc
    83041 ttcctaaaac ctaaagtttg tgatataatt atcaagaaaa aagatttagg agtttattat
    83101 ggtttcttca gaatttatct caaagattga atttgcttgc aataagaaag aaagtcttta
    83161 tagtcaaagc aaatttaagt atgcgattcg ttcgatgttc gcaggtgcat ttttaacctt
    83221 cagtactgct gcaggtgcag ttggggctga cttgattaat aaaattgcac caggtagtgg
    83281 acgcttcctc tttccattcg tttttgcttg gggcttggcc tacattgttt ttttgaatgc
    83341 cgagttggtc acttcaaaca tgatgttctt gactgctggt agtttcttaa aaaaaatctc
    83401 ttggagaaaa acagctgaga ttttactata ctgtaccttg ttcaacctta tcggagcctt
    83461 gatagcaggg tggggctttg ctcattcggc agcctatgcg aatctgacac acgatagttt
    83521 catctcaggt gttgttgaga tgaagttagg ccgctcaaat gaattggtct tgcttgaggc
    83581 gattttggca aatattttcg taaatattgc gattctgtca tttattttgg tcaaagatgg
    83641 tggtgccaaa ctttggcttg tgttgtcagc tatttacatg tttgtattct taacaaacga
    83701 gcacattgcg gcgaactttg cttctttcgc gattgtgaaa ttcagtgttg ctgcggattc
    83761 aattgccaac ttcggtgttg gaaatatgct tcgccactgg ggtgtgactt tcatcggaaa
    83821 ctttatcgga ggaggcctct tgatgggtct tccatatgcc ttcctcaata aaaacgaaga
    83881 tacttatgta gattaagaaa atgagcacga ttgagtcgtg cttttttcat tttcaaaata
    83941 aggtaatagc tatttcttat atcaaaatat agaaaactga tatttgtaaa ctataactca
    84001 aggtgctaca atatccttaa taaaatgata tggaggtcac cttatgactt gtgattttaa
    84061 atttgaaact ctacaactac atgctggtca agttgtggct ccagctacta agtctcgtgc
    84121 agtgccgatt tatcaaacaa catcttttat ttttgatgac acgtaggaag gtgctgatct
    84181 gtttgccttg aggaaaccag ggaacattta tactcgtatc accaatccta caacagctgc
    84241 ccttgaaggt ggtgttgaag cgctagcaac agcatcaggt atgactgcag tgacttatac
    84301 gattttggcg cttgcccatg ctggtgacca tgtagtggct gcttcgacta tttacggtgg
    84361 aaccttcaat cttttgaaag aaccccttcc tcgttatggt atcacaacaa cctttgtcga
    84421 tgttgataat ttggaggaag tagaagcagc tatcaaagac aataccaagc ttgtcttgat
    84481 tgaaaccttg ggtaactcct tgattaatat tccagacctg gaaaaactgg cagagattgc
    84541 tcataaacat caaatcccac ttgtgtcaga caatactttt gcaatacctt atttgattaa
    84601 cgtcttctct catggcgttg acattgccat tcactctgcg actaagttta tcggtgggca
    84661 tggtacaact attggaggaa taattgtcga tagtggtcgt tttgactgga cggcttcagg
    84721 gaaattccct caatttgttg acgagggtcc aagctgccac aatttgagtt atacttgtga
    84781 tgtgggtgca gcagccttta ttatagctgt tcgagttcaa ttgcttcgtg atacaggtgc
    84841 agccttgtca ccattcaatg ctttcctctt gctacaaaga cttgaaacct cttcacttcg
    84901 tgtggaacgc catgtacaaa atgctgagac aattgttgat tttcttgtca accatcctaa
    84961 ggtagaaaag gtaaattatc caaaacttgc agatagtcct tatcatgcct tggctgagaa
    85021 atacttgcca aaagatgtcg gttcaatctt taccttccat gtcaaaggtg gcgaggaaga
    85081 agcacgcaag gtcattgata atttagaaat cttttctgac cttgcaaacg cggcagatgc
    85141 taaatcgctt gttgtccatc cagcaacaac cactcacggt caattgtcag aaaaagacct
    85201 agaagcagca ggtgtcacac caaactaaat tcgtttgtca atcggtcttg aaaatgtaga
    85261 agatttgatt gaagacttgc gcttggcctt ggaaaaaatt taaagtaaaa gaagataaac
    85321 agtgggcttc gactcactgt ttttgatttt ccctcaggca tgatataatg gttaaagaag
    85381 tctagaaaga ggaacgatat gaacgaaatc aaatgtccca actgtgggga agtctttaca
    85441 gtaaatgaga gtcagtatgc cgaactcttg tcccaagtga gaacggcaga gtttgataag
    85501 gaactacacg ataggatgaa gcaggaactg gccttggctg agcaaaaggc catgaatgag
    85561 caacagacta aactggctca gaaggatcaa gaaattgcgc aattacagag tcagatccaa
    85621 aactttgata cagaaaaaga attggccaag aaagaggttg aacagacaag ccatgaggct
    85681 ctcttggcta aggacaagga agtacagctc ttagaaaatc agttggctac cttgcgtttg
    85741 gagcatgaaa atcaactgca aaagaccctt tctgacctag aaaaagaacg ggatcaggtt
    85801 aaaaaccaac tacttttgca ggaaaaggaa aatgaattat ctttggcttc tgttaagcaa
    85861 aactacgaag cccagctcaa ggcagctagt gaacaagtcg agttttataa ggattttaag
    85921 gctcaacaat ctacaaaagc gattggggaa agcctagaac agtatgcaga gagtgagttt
    85981 aacaaggttc gtagtttcgc ctttccaaat gcttactttg agaaggataa caaggtctct
    86041 tcgcgtgggt ctaaagggga ctttatcttc cgtgagtgtg atgaaaatgg agttgaaatc
    86101 atttctatca tgtttgagat gaaaaacgaa gcagacggaa cagagaagaa gcacaagaat
    86161 gcagattttt acaaggaatt ggacaaggac cgtcgggaga agaactgtga gtatgccgtt
    86221 ttggtgacca tgcttgaggc cgataatgac tactttaaca cagggattgt tgacgtcagc
    86281 cacgagtatg aaaaaatgta tgttgttcgt cctcaattct ttatccagtt gattggtctc
    86341 ttacgtaatg cggcgctaaa ttccctaaaa tacaagcagg agttggcctt ggttcgcgag
    86401 caaaatattg acattacgca ttttgaggaa gacttggatg cctttaagct agcttttgct
    86461 aagaactata attcagcttc gactaacttt ggaaaagcta ttgatgaaat cgacaaggcc
    86521 atcaaacgca tggaagaggt taagaaattc ctgactacat ctgaaaacca actccgtcta
    86581 gctaacaaca aattggaaga tgtctctgtt aaaaaattga cccggaaaaa tccaacaatg
    86641 aaagcgaagt tcgaagcact gaagggggag tagaaagcaa aaatgaacgg tattatcaac
    86701 ttaaaaaaag aagcaggaat gacctcgcat gatgcggttt ttaaactgcg taagattttg
    86761 ggaaccaaga aaattggtca tggtggaacc ttggatccgg atgtggtggg tgttttgccg
    86821 attgcggttg gcaaggcgac acgcatggtc gagtttatgc aggacgaggg taagatctat
    86881 gagggggaaa tcattctggg ctattccacg acgactgagg atgctagtgg ggaagtggtc
    86941 gcagaaaccc ctgttttgtc tcccttggat gaaaagcttg ttgatgaagc gattgctagc
    87001 ttgactgggc ctattactca gattccccct atgtattcgg cagttaaggt taatggtcgc
    87061 aagctctatg agtatgcgcg tgctggtcag gaagtggagc gtccagaacg tcaggtgacc
    87121 atttatcaat ttgagcgaac aagtccgatt tcttatgatg gccaacttgc ccgattcact
    87181 tttcgtgtaa aatgcagtaa agggacttac atccgtactt tgtcagttga tttgggtgaa
    87241 aagcttggtt atgcggctca tatgtcccat ttgactcgta ctagtgctgc tggcttacaa
    87301 ttagaagacg ctcttacctt ggaggaaatt gctgaaaaag tagaggctgg gcaattagat
    87361 tttctccatc ctttagagat tgggacaggt gaccttgtca aagttttcct aactccagaa
    87421 gaggctacag aagttcgctt tggtcgtttt attgagctag accaaacgga caaagaactg
    87481 gctgcctttg aagatgataa attgttagcc attctagaaa aacggggcaa tctctataag
    87541 ccaaggaagg tttttagcta gatcgtttag gaataaaaat cgggtgatag ataacaattg
    87601 cttgataaac ccccatacta atagtagaat ggttttggga attataatat tccaattgtt
    87661 gcgagttgta gatactcaaa taatctatat agaaatttag aggtgtgaaa tgaagcaact
    87721 taaaattctt tcagataaat atttagagtc catgacaggt tctggtggga acttaggtct
    87781 aggatttggt gtgataattc catgatgtga aatgagtttc gagaaagggt ggagcaactt
    87841 cttcaacaaa aagaaataaa tgaaaatagt gagttgagtc acctgtttcg tcttgctata
    87901 caaaatttag acagaaatga aaaataccaa tcggtcatgg ccaatttgag tcaagggttg
    87961 tcactttacc tcatgacgca tcattaccag gcacctaagt ctgtcattga ttttggttta
    88021 tggattgcca aagctcctag ccaggaaaga gggagactgg ctttcttgca gatgcttgct
    88081 caaaccctac agggctttcg ttaaaactgt cgaacatcag agggaagact ctggtgtttt
    88141 ttgctgatga gactataaat tttgtaaaaa atgtgataga atagacgacg gataaaataa
    88201 cggaggatag catgcaaaat agaccaatca ttattggagt gacaggtggt tctggtggtg
    88261 gtaaaaccag tgtttcaaga gccattttat cgcattttcc tgatgaaaag atttccatga
    88321 ttgagcatga ttcatactac aaggatcagt ctcatttgac ctttgaagag cgtgtcaaaa
    88381 ccaactatga ccatcctttt gcctttgata cagacttgat gatcgagcag attaaggaat
    88441 tgttggcagg gcgtccggtg gacatcccga cctacgacta tacagagcat acacggagta
    88501 gcaagaccta tcgtcaggag cctcaagatg tctttatcgt tgagggcatt ttggtcttgg
    88561 aggacaagcg tctgcgcgat ttgatggata tcaagatttt tgtggatacg gatgacgatg
    88621 tgcgtattat tcgtcgtatc aagcgtgata tggaggaacg tggccgtagc cttgatagcg
    88681 ttattaacca gtacttaggt gtggtcaaac caatgtacca ccagtttatc gagtcaacta
    88741 agcgttatgc tgatatcgtc attcctgaag gggttagcaa taccgtggct atcgacctgt
    88801 tgacgaccaa gattgcaaag attttggaag aagctcgaaa cagcaaataa tcacatgtgg
    88861 aggccttgcc tcctttttct atttttccct cataatggta cataaatgga gatttttagg
    88921 catatttttg gtataataat acccataaaa gagcaagtaa atgaatagta ggtggagatg
    88981 gaaaagtatt tatcggtaac aactttgacc aaatatctga aaatgaaatt cgataaagac
    89041 ccatacttgg aacgggtcta tttaactggt caagtttcca actttcgtaa acgacctact
    89101 caccaatatt tctccctaaa ggatgaccat gcagttattc aagcgaccat ctggtctggg
    89161 atttatcaga aattagggtt tgacctggaa gaaggaatga agatcaatgt gattgggcgt
    89221 gtacaggtct atgaaccaag tggtagctac tccatcatca ttgaaaaagc tgagcctgat
    89281 ggggttgggg cgcttgcgat tcagtttgaa caacttaaga aaaaattgac agaagaaggc
    89341 ctgtttcaag aacgcttcaa gcaagctcta ccccaatttt ctaagagaat tggggtagta
    89401 accagccgta gtggagccgt tattcgagat attatcacga ccgtcagcag gcgattccca
    89461 ggtgttgaca tccttcttta tcctaccaag gttcaaggtg aaggggctgc ggaggaaatt
    89521 gctagaaata ttgcgcgtgc taatcaacgg gacgatttgg atttgctcat tattggtcgt
    89581 ggaggtggtt ctattgagga tctctgggcc tttaacgaag aaattgtggt acgagctatt
    89641 tttgaatctc gtttgccagt tatctctagt gtggggcatg agacggatgt gaccttggca
    89701 gattttgtgg cagatcgacg cgctgcaacg ccaacagcgg cggctgaact ggcaacacct
    89761 gtgaccaagt tggatgtatt agctcatttg caaaatcagg aaaaacggat ggcaacggca
    89821 gtccgaaatg ttctatctaa gaaacaagag gctttgaaaa aatgcagtca gtctgttatc
    89881 tttagacaac ctgagcgctt gtatgacggt tatttgcaac gcttggacca actgcaactg
    89941 cgtttgaaac aaagtttgcg aactcggatt tctgataaca aacaattagt tcaagcaaga
    90001 actcatcaat tagtacaatt atcacctgtt accaaaatcc aacgctatca agaccgttta
    90061 ggacagttgg acaagctctt aggtagccaa atggcgttag tttatgacgc caaggttgct
    90121 gaggccaagc gactttcgga agctttgctc atgttggata ctagccgaat cgtggcgcgt
    90181 ggttatgcta ttgtcaaaaa agaagagtcc gttgtagatt cggttgagag tttgaagaaa
    90241 aaagaccaag taacgctttt gatgcgagat ggtcaagtag aattagaggt taaagatgtc
    90301 aaaacaaaag aaatttgagg aaaatctagc agaactggaa accattgtcc aaagtttgga
    90361 aaatggtgaa attgctctgg aagatgcgat tactgccttt caaaagggca tggtcttgtc
    90421 aaaagagctc caagctacgc tggacaaggc tgaaaagacc ttggtcaagg tcatgcaaga
    90481 agacggaaca gaaagtgatt ttgaatgaaa aagcaagaaa aattagctct tgtcgagtcg
    90541 gctttggaag atttttatgg agaccagcag tttgcctcta gtttacggga gtctgttctc
    90601 tattctattc atgctggtgg caagcgtatt cggccttttc tcttgttaga agttctggaa
    90661 tccttgcagg ttaccatcaa acctgctcac gcgcaggtag ctactgcctt ggagatgatt
    90721 catacaggga gcttgattca cgatgacctt cctgctatgg atgatgacga ttatcgaaga
    90781 gggcggttaa ccaatcacaa gaaattcggt gaagctatgg ccattttggc tggagatgcc
    90841 ttattcttag acccatatgc cttgattgcg caggcagatt tgccaagtca gatcaaggtg
    90901 gacttgattg ccaacttatc ccttgcttca ggtagtctgg gtatggtggc agggcaagtt
    90961 ttggatatgg agggcgaaca ccagcacttg tctctggaag aacttcagac tattcatgcc
    91021 aataagactg ggaagttact agcctatccc ttccaagcgg cagctattat agctgaattg
    91081 tcacctgaaa tgcaggtgaa gctgaaaact gtgggtgaat tgattggact tgcttttcaa
    91141 gtcagagatg atgtactgga tgtgacagct agttttgagg aaatcggcaa gacacctcaa
    91201 aaggatctgc aggcagaaaa atcaacctat cctgccttgt tgggcttgga agagtccatt
    91261 gccttttgta accaaaccct ggatcaagct aatgaaaaat tagaagaaat tgcccagcag
    91321 cttccctttg aaacagaatc gattgtaagt gtagtagaaa gtttgagaat caatggctaa
    91381 ggaaagagtg gatgtactag cttataaaca ggggttgttt gaaacgagag agcaggccaa
    91441 gcgaggtgtg atggctggtc tagtcgtagc agtccttaat ggagaacggt ttgacaagcc
    91501 aggagagaaa attccagatg acaccgaatt aaaactcaag ggggagaaac tcaagtatgt
    91561 cagccgtggt ggtttgaaac tggaaaaggc cttgcaggtc tttgatttgt cggtggatgg
    91621 cgcgactacg attgatatcg gggcctctac tggaggtttt accgatgtca tgctacagaa
    91681 tagtgccaag ttggtctttg cagtcgatgt tggtaccaat cagttggctt ggaaattacg
    91741 ccaagaccca cgagttgtca gcatggagca gttcaatttt cgctatgctg aaaagactga
    91801 tttcgagcag gagccgagct ttgccagtat tgatgtgagt ttcatttccc ttagtctgat
    91861 tttgccagcc ttgcacagtg tcttggctga tcaaggtcag gtggtagcac ttgtcaaacc
    91921 tcagtttgag gcaggacgtg agcagattgg gaaaaatgga attattcgag atgctaagat
    91981 tcatcagaat gtccttgaat ctgtaacagc tatggcagta gaggcaggtt tttcagtcct
    92041 tggcttggac ttttctccca tccaaggtgg acatggaaat attgaatttt tagcgtattt
    92101 gaaaaaagaa aagtcagcaa gcaatcagat tcttgctgag attaaagaag cagtagagag
    92161 ggcgcatagt caatttaaaa atgaataaaa aagaaagact tgaaaaaatt agaagattgg
    92221 tgacagatta tcaaatcggc acgcaagaag aaattgtaga acatttgaaa gaagcaggta
    92281 tcactgccac tcaggcgacg gtatcccgag atatcaaaga gttaggtatt gtcaaaattc
    92341 ctttgagaga caacacctat gtctacgaat tgccaaaatc aatcgtaaaa agtctgcaac
    92401 tggctgaaga caatatcgaa tcggctgaat tgatggataa gatgatcaat ctccaagtta
    92461 ttccaggaaa tacggctttt gtaaaagctc agttaatcga gacttttgca gacaagattt
    92521 ttagctgttt gactgatgat agctcgattt tagtcattgc cagaagtgga agtctagcag
    92581 aggaaatctt tgaacaagta aaaaattggt aggtctatat gttacttgaa atttcgataa
    92641 aaaactttgc cattattgag gctatttccc tcaattttga aaaggggatg actgtcctga
    92701 ctggtgaaac gggtgcaggg aagtcgatta tcattgatgc catgaatatg atgttgggag
    92761 ctcgtgcgac gacagatgtt attcgtcatg gtgcaccaaa ggcagagatt gaggggcttt
    92821 tctcagttga gaatagtcgt cttttacagg aaatttttga tgagcaaggt ttagaattag
    92881 gtgatgaaat tatcatccgt cgggaaatct tgcaaaatgg tcgtagtatc agccgtgtaa
    92941 atggtcagat ggttaatctg tctgttttgc gaactattgg gcaacatctt gtagatattc
    93001 atggtcagca tgaccatgag gagttaatgc gtccccaact gcatatccag atgttggatg
    93061 aatttggtga tgccgctttt tgggacttga aagaaaccta tcaaacgagt tttgatgcct
    93121 atcggaaaat gcgcaagcag gttctggaag tcaagaaaaa ccaacaggaa cacaaggcac
    93181 gtatcgaaat gttggaattt caaatggcag agattgaggc agcaaacttg caggctggag
    93241 aagacttgga tctcaatcaa gagcgagata aactcctcaa ccacaaaaat attgcggata
    93301 cactgaccaa tgcctacagt atgttggaca atgaagattt ttcaagtctg gccaatgttc
    93361 gttcagccat gaatgacatg gaaagtgtcg aagagtatga ccctgaatac cgtgaaattt
    93421 caagctctct gtctgagacc tactatgttt tagaagacat tagcaaacgt ttggaagcta
    93481 tcattgagga ccttgatttt gatggcaatc gcctcatgca ggttgagaat cgtttggacc
    93541 tccttcatac tattactcgt aagtatggtg ggactgttga tgatgttttg ctttattttg
    93601 ccaagattac ggaagaatac aatctcttga caggcaataa tctttcgtct gaggacatgg
    93661 aagcagagct taagaagttg gaagtcaatc ttgtcaattt ggcaggtcaa cttgcttctg
    93721 ctcgtcataa tttggctcag caactcgaag ctgagattaa acaagaactg caagatcttt
    93781 atatggaaaa agcccagttt caggttcgtt ttagtaaggg aaaattcagt cgtgagggaa
    93841 ataaaatggt tgagttttat atttcaacca accctggaga agactttaaa cccttggtta
    93901 aggttgcttc tggaggggaa ttatctcgtc tcatgttagc cattaagtct gccttttcac
    93961 gtaaagaagg caagactagc attgtctttg atgaggtgga tacgggagtt tcaggtcgtg
    94021 ttgctcaagc tattgctcag aaaattcata aaattggtca gcatggtcag gttttggcta
    94081 tctcccattt gccacaagta attgcgattg cagattatca attctttatt gagaagatta
    94141 gtaatgacca ttcaacggtt tcgactgttc gtctcttgac ggtcgaagag cgagtggagg
    94201 aagttgccaa gatgttggca ggtgatgatg tgacagaagc agccctgacg caagcaagag
    94261 aattgttgag aaacagggag aaataagatg acagattatt atgtaattgg agatgttcac
    94321 ggaaaagctg ggatgctgga agaccttctc aaaacctggg atggtcagcc ccagttgctc
    94381 tttctaggtg atttgattga cagaggtgag gatagtcacc gtgttcttga aatggtcaag
    94441 gacttggtgg acaatcaagg ggctatctgt ttgtccggaa accacgagta tatgtttttg
    94501 acttggctag atgacccaga agaaagttat gaccattata gtcgcaatgg tggagataca
    94561 accattaact ctatcctagg tcgtcccttg gatgcaccag ttgatggagt agaagatgcc
    94621 aagcgggttg ccgctgaagc ggcagacttg gtcgaattca ttcgtcaaat gccatttgta
    94681 gtagagacag acaagtatat ctttgttcac gcaggtattg atttgacctt ggacgactgg
    94741 catgaaacaa cagattataa aaaagtatgg cttagaaaac cattccacgg agctgaaaat
    94801 catactggaa aaaccattgt cttcggtcat acaccggtct atggtttatt acagcaagaa
    94861 cgcggtacat ctgagctttg gactacagaa gatggcaaga ttggaatgga tggaggagct
    94921 gtttatggtg gtgtccttca cgggattgtc tttacagacc aaggaatgac agaacaccac
    94981 tttatcgaaa atgacggctt tgtcgctgaa gattagtact cctagcaggg tatggtcttg
    95041 tcaaaatatc aaaaacaatt tataataaat agataccctg aaaggaagag aatcatgaac
    95101 ttagaagaat tgaaaaaacg acaggagaag atccgtaact tctctattat cgcccatatt
    95161 gaccacggaa aatcaactct agcagaccgc attttggaaa aaacagagac ggtttcaagt
    95221 cgtgaaatgc aggcccagct tttggatagc atggagctag agcgggaacg tggaattact
    95281 attaagttga atgccatcga gttgaattac actgcaaaag atggggaaac ttatattttc
    95341 cacttgattg acacaccagg gcacgttgac tttacctatg aagtttcacg ttcgctagct
    95401 gcctgtgagg gtgctatttt ggtggtcgat gcggctcaag gaattgaggc tcaaactctt
    95461 gccaacgttt atctggcttt ggataatgat ttggaaatca tgcctatcat taataaaatt
    95521 gacctgccgg ctgcagatcc ggagcgcgtg cgtacagaga ttgaagatgt gattggtttg
    95581 gatgccagtg aagcagtttt ggcttctgcc aaggctggta ttgggattga agaaatcctc
    95641 gagcaaattg tagaaaaagt accagcacca acgggtgatg tgacggcgcc acttaaggcc
    95701 ttgattttcg actctgttta cgatgcttac cgtggggtta tcctccaagt gcgtgtcatg
    95761 gacggagtgg tcaaacctgg tgataagatt cagctcatga gcaatagtaa gacctttgat
    95821 gtggccgaag tcggtatttt tacaccaaaa gcggttggtc gtgatttcct tgcgactggt
    95881 gatgttggtt acattgcggc gtctatcaag acggttcagg atactcgtgt gggtgatacc
    95941 gttaccttgg caaccaatcc tgcggcagaa ccattacatg gttataagca gatgaatcct
    96001 atggtctttg cgggtctcta cccaatcgaa tcaaacaagt acaatgacct gcgtgaagcg
    96061 cttgaaaaat tgcaactgaa tgatgctagt cttcagtttg aaccagaaac atctcaggca
    96121 cttggatttg gtttccgttg tggatttctt ggacttctcc atatggatgt tatccaggaa
    96181 cgtttagagc gtgagttcaa tattgacctc atcatgacag ctccgtctgt tatttacaaa
    96241 gttaatttga ccgacggtga gtctatggat gtgtctaacc catctgagtt tccagaccca
    96301 actaagattg cgaccattga agagccttat gtcaaggcgc aaatcatggt accacaggag
    96361 ttcgtcggag cagtaatgga gctagctcag cgtaagcgtg gggactttgt gactatggac
    96421 tatattgatg ataaccgtgt caatgttatc tatcaaattc ctcttgctga aattgtcttt
    96481 gacttctttg ataaacttaa gtcttcgaca cgtggttatg caagctttga ctacgaattg
    96541 tcagaatatc gcccatctaa gctggtgaaa atggatattc ttctcaatgg agataaggtg
    96601 gatgccctca gctttatcgt tcacaaggac tttgcctacg aacgtgggaa actcatcgtt
    96661 gataaactca agaaaatcat ccctcgccaa caatttgaag ttccaatcca agcggctatt
    96721 ggacacaaga ttgtcgctcg tactgatatc aaggcccttc gtaagaacgt acttgctaaa
    96781 tgttatggtg gtgacgtttc tcgtaagcgt aaactccttg aaaaacaaaa agctggtaag
    96841 aaacgcatga aatccatcgg atcagttgaa gttccgcaag aagccttcct cagcgtcttg
    96901 agtatggatg aagaataagt tatcagaaat gcctttcctt gttcacagga aatttataag
    96961 aatcaatagt aaagcaggct tagatggtct gcttttttag tttttatact cttcgaaaat
    97021 ctcttcaaac cacgtcagcg tcgccttacc gtatgtatgg ttactgactt cgtcagtttc
    97081 atctacaacc tcaaaaccat gttttgagct gacttcgtca gtttcatcta caacctcaaa
    97141 actgtgtttt gaacaacctg cggctagctt cctagtttgc tctttgattt tcattgagta
    97201 ttagaacaga aaaaatgctt ggagtatttg tttgtgtgtt tacttttata taacaaacta
    97261 taaacacaac aaaaatataa aaaaagagac aaaaaagaac agaaagtaat taacaacgat
    97321 ttcatatagt gttatactta tagcataaag ttaatggaaa gaagggaaaa ccttatggta
    97381 ttagattatt tctttgacaa aaaccttgtg ttttgcttag aagcggataa tcaagaataa
    97441 ctctttgatc aggtagcaag cttgttggag gaacgagaaa ttgt
//
LOCUS       DAVBEM010000002        84735 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVBEM010000002 DAVBEM010000000
VERSION     DAVBEM010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 84735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84735
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.002"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            <1..722
                     /locus_tag="VQ548_000102"
     CDS             <1..722
                     /locus_tag="VQ548_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HET2653036.1"
                     /translation="KKDAHGIALKLLSDPNREQFQHDNRQVELKILARHIHRLKKKQS
                     DWKVQYTRCLDIIFPELDKIVEKHSEYTYQLLTCYPNPQKRLEAGFDKLIEIKRLTAS
                     KIQDILSVAPRSIGTTSPAREFEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGN
                     RLEAVILAEIRNIHAFDNPAQLQAFAGLDSSIYQSGQIDLAGRMIKRGSPHLRWALIQ
                     AAKACPRFSPAFKAYLKTKLE"
     gene            complement(1023..2912)
                     /locus_tag="VQ548_000103"
     CDS             complement(1023..2912)
                     /locus_tag="VQ548_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HET2653037.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSLFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            3050..4615
                     /locus_tag="VQ548_000104"
     CDS             3050..4615
                     /locus_tag="VQ548_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET2653038.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKKPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMCKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            4615..5379
                     /locus_tag="VQ548_000105"
     CDS             4615..5379
                     /locus_tag="VQ548_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2653039.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQARPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLILNENQRAN"
     gene            complement(5578..5793)
                     /locus_tag="VQ548_000106"
     CDS             complement(5578..5793)
                     /locus_tag="VQ548_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653040.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
     gene            complement(6664..7914)
                     /gene="ilvA"
                     /locus_tag="VQ548_000107"
     CDS             complement(6664..7914)
                     /gene="ilvA"
                     /locus_tag="VQ548_000107"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HET2653041.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(7964..8320)
                     /locus_tag="VQ548_000108"
     CDS             complement(7964..8320)
                     /locus_tag="VQ548_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET2653042.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(8558..8794)
                     /locus_tag="VQ548_000109"
     CDS             complement(8558..8794)
                     /locus_tag="VQ548_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653043.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(8901..9923)
                     /gene="ilvC"
                     /locus_tag="VQ548_000110"
     CDS             complement(8901..9923)
                     /gene="ilvC"
                     /locus_tag="VQ548_000110"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET2653044.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVVEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(9989..10465)
                     /gene="ilvN"
                     /locus_tag="VQ548_000111"
     CDS             complement(9989..10465)
                     /gene="ilvN"
                     /locus_tag="VQ548_000111"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HET2653045.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(10458..12158)
                     /locus_tag="VQ548_000112"
     CDS             complement(10458..12158)
                     /locus_tag="VQ548_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HET2653046.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(12359..14026)
                     /locus_tag="VQ548_000113"
     CDS             complement(12359..14026)
                     /locus_tag="VQ548_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HET2653047.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(14029..14394)
                     /locus_tag="VQ548_000114"
     CDS             complement(14029..14394)
                     /locus_tag="VQ548_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2653048.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(14551..14739)
                     /locus_tag="VQ548_000115"
     CDS             complement(14551..14739)
                     /locus_tag="VQ548_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HET2653049.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(14855..15031)
                     /locus_tag="VQ548_000116"
     CDS             complement(14855..15031)
                     /locus_tag="VQ548_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET2653050.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
     gene            complement(15142..15291)
                     /locus_tag="VQ548_000117"
     CDS             complement(15142..15291)
                     /locus_tag="VQ548_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET2653051.1"
                     /translation="MDKVETTIKSLCVHHYNLKFYVFNDDLPREWFQLMEKRLETLNS
                     EIVNV"
     gene            complement(15603..17147)
                     /locus_tag="VQ548_000118"
     CDS             complement(15603..17147)
                     /locus_tag="VQ548_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HET2653052.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            17360..17662
                     /gene="gatC"
                     /locus_tag="VQ548_000119"
     CDS             17360..17662
                     /gene="gatC"
                     /locus_tag="VQ548_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HET2653053.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            17662..19128
                     /gene="gatA"
                     /locus_tag="VQ548_000120"
     CDS             17662..19128
                     /gene="gatA"
                     /locus_tag="VQ548_000120"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HET2653054.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDANNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDTKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            19128..20570
                     /gene="gatB"
                     /locus_tag="VQ548_000121"
     CDS             19128..20570
                     /gene="gatB"
                     /locus_tag="VQ548_000121"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HET2653055.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDLHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            20699..21259
                     /gene="efp"
                     /locus_tag="VQ548_000122"
     CDS             20699..21259
                     /gene="efp"
                     /locus_tag="VQ548_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HET2653056.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            21281..21670
                     /locus_tag="VQ548_000123"
     CDS             21281..21670
                     /locus_tag="VQ548_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2653057.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGVYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            21663..22085
                     /gene="nusB"
                     /locus_tag="VQ548_000124"
     CDS             21663..22085
                     /gene="nusB"
                     /locus_tag="VQ548_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HET2653058.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTNVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKVGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(22134..22511)
                     /locus_tag="VQ548_000125"
     CDS             complement(22134..22511)
                     /locus_tag="VQ548_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2653059.1"
                     /translation="MVLSNGQPTFLSTILSFVLLVIIGPVFEETLDRGYFMNTFFPKS
                     KYYLDVILSGLIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDNLRLTILCHSFF
                     NFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(22852..23037)
                     /gene="briC"
                     /locus_tag="VQ548_000126"
     CDS             complement(22852..23037)
                     /gene="briC"
                     /locus_tag="VQ548_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HET2653060.1"
                     /translation="MTGTETFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRTG"
     gene            complement(23196..23963)
                     /locus_tag="VQ548_000127"
     CDS             complement(23196..23963)
                     /locus_tag="VQ548_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HET2653061.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(23960..24826)
                     /locus_tag="VQ548_000128"
     CDS             complement(23960..24826)
                     /locus_tag="VQ548_000128"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HET2653062.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(24863..26230)
                     /gene="accC"
                     /locus_tag="VQ548_000129"
     CDS             complement(24863..26230)
                     /gene="accC"
                     /locus_tag="VQ548_000129"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HET2653063.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(26242..26664)
                     /gene="fabZ"
                     /locus_tag="VQ548_000130"
     CDS             complement(26242..26664)
                     /gene="fabZ"
                     /locus_tag="VQ548_000130"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HET2653064.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(26661..27146)
                     /locus_tag="VQ548_000131"
     CDS             complement(26661..27146)
                     /locus_tag="VQ548_000131"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HET2653065.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(27149..28384)
                     /gene="fabF"
                     /locus_tag="VQ548_000132"
     CDS             complement(27149..28384)
                     /gene="fabF"
                     /locus_tag="VQ548_000132"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HET2653066.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(28406..29137)
                     /gene="fabG"
                     /locus_tag="VQ548_000133"
     CDS             complement(28406..29137)
                     /gene="fabG"
                     /locus_tag="VQ548_000133"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HET2653067.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(29171..30091)
                     /gene="fabD"
                     /locus_tag="VQ548_000134"
     CDS             complement(29171..30091)
                     /gene="fabD"
                     /locus_tag="VQ548_000134"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HET2653068.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(30084..31058)
                     /gene="fabK"
                     /locus_tag="VQ548_000135"
     CDS             complement(30084..31058)
                     /gene="fabK"
                     /locus_tag="VQ548_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HET2653069.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(31177..31401)
                     /locus_tag="VQ548_000136"
     CDS             complement(31177..31401)
                     /locus_tag="VQ548_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET2653070.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(31461..32435)
                     /locus_tag="VQ548_000137"
     CDS             complement(31461..32435)
                     /locus_tag="VQ548_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HET2653071.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANNRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(32435..32869)
                     /locus_tag="VQ548_000138"
     CDS             complement(32435..32869)
                     /locus_tag="VQ548_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2653072.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(32963..33748)
                     /locus_tag="VQ548_000139"
     CDS             complement(32963..33748)
                     /locus_tag="VQ548_000139"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HET2653073.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            34073..35437
                     /locus_tag="VQ548_000140"
     CDS             34073..35437
                     /locus_tag="VQ548_000140"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HET2653074.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            35440..35811
                     /locus_tag="VQ548_000141"
     CDS             35440..35811
                     /locus_tag="VQ548_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HET2653075.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            36025..37299
                     /gene="serS"
                     /locus_tag="VQ548_000142"
     CDS             36025..37299
                     /gene="serS"
                     /locus_tag="VQ548_000142"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HET2653076.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGTDEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(37324..38223)
                     /locus_tag="VQ548_000143"
     CDS             complement(37324..38223)
                     /locus_tag="VQ548_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HET2653077.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACSGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(38333..38881)
                     /locus_tag="VQ548_000144"
     CDS             complement(38333..38881)
                     /locus_tag="VQ548_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HET2653078.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(39099..40421)
                     /locus_tag="VQ548_000145"
     CDS             complement(39099..40421)
                     /locus_tag="VQ548_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HET2653079.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGARFIWLYRVFFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(40512..40600)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(40764..43100)
                     /locus_tag="VQ548_000146"
     CDS             complement(40764..43100)
                     /locus_tag="VQ548_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HET2653080.1"
                     /translation="MNKKILETLEFDKVKALFDPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVHFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(43204..43752)
                     /locus_tag="VQ548_000147"
     CDS             complement(43204..43752)
                     /locus_tag="VQ548_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HET2653081.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIFYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(43749..44051)
                     /gene="zapA"
                     /locus_tag="VQ548_000148"
     CDS             complement(43749..44051)
                     /gene="zapA"
                     /locus_tag="VQ548_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HET2653082.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            44138..45019
                     /locus_tag="VQ548_000149"
     CDS             44138..45019
                     /locus_tag="VQ548_000149"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HET2653083.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQLVEENRGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TSDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLSVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            45023..45637
                     /gene="lepB"
                     /locus_tag="VQ548_000150"
     CDS             45023..45637
                     /gene="lepB"
                     /locus_tag="VQ548_000150"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HET2653084.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            45916..48282
                     /locus_tag="VQ548_000151"
     CDS             45916..48282
                     /locus_tag="VQ548_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HET2653085.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTHLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(48330..49613)
                     /locus_tag="VQ548_000152"
     CDS             complement(48330..49613)
                     /locus_tag="VQ548_000152"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HET2653086.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     EDGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(49807..50166)
                     /locus_tag="VQ548_000153"
     CDS             complement(49807..50166)
                     /locus_tag="VQ548_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET2653087.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNRFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNIT"
     gene            complement(50465..51094)
                     /locus_tag="VQ548_000154"
     CDS             complement(50465..51094)
                     /locus_tag="VQ548_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET2653088.1"
                     /translation="MVLSKYYGVADGMNVEGRGSANFIKDNVLITAAHNYYRHDYGKE
                     ADDIYVLPTVSPSQEPFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLG
                     TLGLPTSQKNLTGITVTITGYPSYNFKVHQMYTDKKQVLSDDGMFLDYQVDTLEGSSG
                     STVYDASHRVVGVHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGW"
     gene            complement(51139..51378)
                     /locus_tag="VQ548_000155"
     CDS             complement(51139..51378)
                     /locus_tag="VQ548_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653089.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(51528..51794)
                     /locus_tag="VQ548_000156"
                     /pseudo
     CDS             complement(51528..51794)
                     /locus_tag="VQ548_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(51819..52127)
                     /locus_tag="VQ548_000157"
     CDS             complement(51819..52127)
                     /locus_tag="VQ548_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET2653090.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLRLQIAS
                     "
     gene            complement(52052..52294)
                     /locus_tag="VQ548_000158"
     CDS             complement(52052..52294)
                     /locus_tag="VQ548_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET2653091.1"
                     /translation="MSLADLLEELEAAKDSKKARPMEAYMRHQFSFLGIAVPERNKLY
                     KNIYQKRKKQRLSIGILQTLAGKRSLENTNMWLLTI"
     gene            complement(52295..52927)
                     /locus_tag="VQ548_000159"
     CDS             complement(52295..52927)
                     /locus_tag="VQ548_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2653092.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(52941..53936)
                     /locus_tag="VQ548_000160"
     CDS             complement(52941..53936)
                     /locus_tag="VQ548_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2653093.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLYDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLDQEEEIIEKERKRIARDLHDTVSQELFAAHIILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFRLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(53933..54631)
                     /locus_tag="VQ548_000161"
     CDS             complement(53933..54631)
                     /locus_tag="VQ548_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HET2653094.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(54709..55719)
                     /locus_tag="VQ548_000162"
     CDS             complement(54709..55719)
                     /locus_tag="VQ548_000162"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HET2653095.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(55703..56710)
                     /locus_tag="VQ548_000163"
     CDS             complement(55703..56710)
                     /locus_tag="VQ548_000163"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HET2653096.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLTPNPDYSLIQETIALMGDFLAVRGQNLRSFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKSEKIIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(56697..57650)
                     /gene="mvaD"
                     /locus_tag="VQ548_000164"
     CDS             complement(56697..57650)
                     /gene="mvaD"
                     /locus_tag="VQ548_000164"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HET2653097.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVIADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YSVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(57632..58510)
                     /gene="mvk"
                     /locus_tag="VQ548_000165"
     CDS             complement(57632..58510)
                     /gene="mvk"
                     /locus_tag="VQ548_000165"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HET2653098.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(58632..58961)
                     /locus_tag="VQ548_000166"
     CDS             complement(58632..58961)
                     /locus_tag="VQ548_000166"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2653099.1"
                     /translation="MTRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMIPHDFPLYLTVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVQ"
     gene            59623..59959
                     /locus_tag="VQ548_000167"
                     /pseudo
     CDS             59623..59959
                     /locus_tag="VQ548_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
     gene            59859..60446
                     /locus_tag="VQ548_000168"
     CDS             59859..60446
                     /locus_tag="VQ548_000168"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653100.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCEIAY
                     ALFAYSKVLEPSMFYNDLHTFHAELKKLLEKVTSNTENLGNLQLSWCEGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKIQQVILA
                     CSERDDHGLLMFQGDSGKADLFDFGIGSRGYIGVY"
     gene            60489..61721
                     /locus_tag="VQ548_000169"
     CDS             60489..61721
                     /locus_tag="VQ548_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2653101.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVHIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLFALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFVTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(61839..62795)
                     /gene="cbpC"
                     /locus_tag="VQ548_000170"
     CDS             complement(61839..62795)
                     /gene="cbpC"
                     /locus_tag="VQ548_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HET2653102.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLRSSGAMA
                     TGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSSGAMATGWYQDGSTWYYLNAGN
                     GDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(62893..63582)
                     /locus_tag="VQ548_000171"
     CDS             complement(62893..63582)
                     /locus_tag="VQ548_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2653103.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(63594..65018)
                     /gene="gndA"
                     /locus_tag="VQ548_000172"
     CDS             complement(63594..65018)
                     /gene="gndA"
                     /locus_tag="VQ548_000172"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HET2653104.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEDQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(65094..66488)
                     /gene="mapZ"
                     /locus_tag="VQ548_000173"
     CDS             complement(65094..66488)
                     /gene="mapZ"
                     /locus_tag="VQ548_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HET2653105.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTNSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(66501..67658)
                     /locus_tag="VQ548_000174"
     CDS             complement(66501..67658)
                     /locus_tag="VQ548_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HET2653106.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARLPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERKLELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(67743..68123)
                     /gene="rnpB"
                     /locus_tag="VQ548_000175"
     ncRNA           complement(67743..68123)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VQ548_000175"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(68144..68473)
                     /gene="gpsB"
                     /locus_tag="VQ548_000176"
     CDS             complement(68144..68473)
                     /gene="gpsB"
                     /locus_tag="VQ548_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HET2653107.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            complement(68543..69070)
                     /locus_tag="VQ548_000177"
     CDS             complement(68543..69070)
                     /locus_tag="VQ548_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HET2653108.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            69136..69732
                     /gene="recU"
                     /locus_tag="VQ548_000178"
     CDS             69136..69732
                     /gene="recU"
                     /locus_tag="VQ548_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HET2653109.1"
                     /translation="MINYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            69729..71888
                     /locus_tag="VQ548_000179"
     CDS             69729..71888
                     /locus_tag="VQ548_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1A"
                     /protein_id="HET2653110.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(72055..77358)
                     /locus_tag="VQ548_000180"
     CDS             complement(72055..77358)
                     /locus_tag="VQ548_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HET2653111.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATANENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLFSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKTPGNSTWYKGNRVVAPEPGSVNRLSITLKSDGQLNASNNDVNLFDTVTLPGAVN
                     DNLKNEKKILLKAGTYGNDRTVVSVKTDNQEGVKADDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVFLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVNDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGQGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSDQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(77659..79641)
                     /locus_tag="VQ548_000181"
     CDS             complement(77659..79641)
                     /locus_tag="VQ548_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2653112.1"
                     /translation="MKSSKLLALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDDQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQGSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            complement(80037..80483)
                     /locus_tag="VQ548_000182"
                     /pseudo
     CDS             complement(80037..80483)
                     /locus_tag="VQ548_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014295150.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(80559..80993)
                     /locus_tag="VQ548_000183"
     CDS             complement(80559..80993)
                     /locus_tag="VQ548_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2653113.1"
                     /translation="MLLVLVSLVHSFGSVSIIAHTIHQKFNLKVPNYRQEEDWARMGL
                     PITRKEISNWHIKASQYYLESLYKLLREKLLEQPLLHADETSYRVLESDSHLTYYWTF
                     LSGKAENQAITLYHHDQRRSGLVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(81069..81920)
                     /gene="rfbD"
                     /locus_tag="VQ548_000184"
                     /pseudo
     CDS             complement(81069..81920)
                     /gene="rfbD"
                     /locus_tag="VQ548_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647909.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
     gene            complement(81986..83035)
                     /gene="rfbB"
                     /locus_tag="VQ548_000185"
     CDS             complement(81986..83035)
                     /gene="rfbB"
                     /locus_tag="VQ548_000185"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HET2653114.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLVAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGIYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            complement(83045..83641)
                     /locus_tag="VQ548_000186"
     CDS             complement(83045..83641)
                     /locus_tag="VQ548_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HET2653115.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     VLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENLEEADVSEADKHHPLLKDVKPLKKEDLE"
     gene            complement(83642..84499)
                     /gene="rfbA"
                     /locus_tag="VQ548_000187"
     CDS             complement(83642..84499)
                     /gene="rfbA"
                     /locus_tag="VQ548_000187"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HET2653116.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGIKLSYAEQPSTDGLAIGEEFISDDSVALIL
                     GDNIYHGPGLSTMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEKPEYP
                     RSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRGFAWL
                     NTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKNEYGQ
                     YLLRLIGEA"
BASE COUNT        24638 a        19291 c        15648 g        25158 t
ORIGIN      
        1 ataagaaaga cgctcatggc atcgctctta aacttctttc tgaccccaat cgtgaacaat
       61 ttcaacacga taatcggcaa gtagaactaa aaatactggc tagacatatt catcgtctca
      121 agaaaaaaca gtctgattgg aaagtacaat acactcgttg tcttgatatc atctttcctg
      181 agttggataa aatcgttgaa aagcattcag aatataccta ccaactcttg acatgctacc
      241 ctaatcctca gaaaaggctt gaggcaggat ttgataagct gatagaaatt aagcgattga
      301 ccgcttctaa aattcaggat atcctctcag ttgcacctcg ttctatcgga acaacatctc
      361 ctgctcgtga attcgaaatc atcaaacatt acaagaggct cattgacaag gcggaaacat
      421 gtgtcaatga cttgatggct gagttcaact cggtcatcac gacggtcact gggattggga
      481 atcgtttaga ggcggtcatt ttagccgaga ttcgaaatat tcatgccttt gataatcctg
      541 ctcaattaca agctttcgct ggactggatt cttctattta tcagtcaggt cagattgatt
      601 tagctggaag aatgatcaaa cggggttccc ctcatctgcg gtgggcactc atacaagctg
      661 ccaaagcatg ccctcgcttt tcacctgctt ttaaggccta tcttaagact aagttagaat
      721 aaggaaaaca ttacaatgta gccatcatcc accttgcaaa aaaacttatc cgaaccctgt
      781 tttatatcct aaaaaagagc tgccatttga cgaacaaaaa gtgatgtaat ttctgaaatt
      841 aacacaggat tacctttgaa aaaatggact ttttcaaggg ctttttgccg tgctctaaaa
      901 tcatcgccaa atcatcaaat tgaaataaga aatagtttag ataaaactat tgacttttct
      961 tatagtttgt cttttttcta tcttccatta tatcatactt tttcagtcta tggtagctct
     1021 ctttaaaagg caccgatact gccgccacct ccgcctccag agaagccacc accagaactt
     1081 ccacttccag aagatacaga gtaggtgctt gctgtatttg cgacactagc ataatggctc
     1141 atttgcgcgc ttgaatgata aaacagactg tgccagccat aagctacata gagattgata
     1201 tctggatttt ccacttgaat ctgatgaacc ttcatcaaat gactaacctt gtccgcatag
     1261 ccaaataagg tcgcatagac caagaggcga ttccagacca caatactttc cagttcagcc
     1321 tgatccaatc gtgcaatctc acgcaacata ttttcaaaac tggtccagag atagtagacc
     1381 tcagctcccg cttcatttag aacaccatca cgattatcta gtcgaagctt ccaataatag
     1441 aaaacagaca aaactaaccc tagaaaacca agtattggca aagggaggta aagatagcca
     1501 tgaacgtcta aactgtacaa gaacaaacca aatccgataa ataggggcag gatagtcaag
     1561 gcacccatac ccacttgcaa ggccttttcc ccaccagtta aaggacgata ataatctggg
     1621 agcccccaga aggaaactcg ttttctcact ccttcttgca tctggttcaa tacctcttca
     1681 aaagaagatt tgagttgaag ccctcttgct tgaatccgtt tttcatcaga aactttggct
     1741 ctacgataaa gactatcaga taccttgtaa tccgcaaaca aattggaaag agtttcttct
     1801 tttttacctg aaaaagctag atttaggcag tctttctcaa agcttgacaa accatcttct
     1861 tttactagcc tcaaaccaac tgcatctcct tctgaaatga tagagacatt cccacggtct
     1921 atcacatcta gcaaggtagc ttgaataagt tgatcaaagg tgaattttcc agctcccttg
     1981 accaagggac tcacttcctc caaggaggtc gagtagactg cttctgataa aaccataggc
     2041 tctaattcca ttggtggttc atagagacga tgatttttgg catatttgac tgaaggagtg
     2101 gtctttcttc tataaataaa atagaagcag acactcaata acaaggagat agaaaggatc
     2161 gaagggagga cccaagtaac aagttgttta ctctgatctt tttctctaac aatcgagtct
     2221 tctatcttat taaactcttc taaacgattc cctttcaatc cctgatccct agcgctagca
     2281 aaatcggtcc gaggccaata ggcatgcaac tcaactccac gcttagccgg aagattgtct
     2341 aaacggatag tataatcaag gttactcttt tcaatcgttc cctctctaaa aagtttccct
     2401 gtatggaaaa agagtttttc agctcccttg tctcccctta catgaaattc aaacttttca
     2461 atagactctg aactatctgt cagaggttgc caatttaatt cagcgatatc atcataaagg
     2521 aaaagtaaat tttttaagtt ccagacgagg tcaacttcaa ctatgtcgcc ctcctgacct
     2581 ggattataga ctctcacagt ataaccatcc gcttcttctg ttacttcgct agtcacatct
     2641 gctagttctg caccgttttt cgcggcctga acctttggat gagggtcaat gtcaaacccg
     2701 ctaggcatct taccagcacg tccaagtccc acgatttgtc ccttaaagtc ctcctcaaac
     2761 tggtaaacta tcttctgtct aaactctgcc gtattatctg catgaatata caaatcccct
     2821 tgataagagt ttatcttgaa atcaatggca aaaacagaga gtggaagaag gcaaaacaag
     2881 cctaacacca gtaagaaaaa agtttttttc atcaactaag cccccttttt atctttctta
     2941 tcattatagc attttttcgt aagtaaaggc ttacttatgt tgaaaaatta cgcatttttc
     3001 gataaaatag gagacagtta ttttttaata gatcagaata ggagaaatca tgagaaaaat
     3061 atacttatct attttcacaa gtctcttgct gatgctagga cttgtcaatg ttgctcaagc
     3121 cgatgaatat ttacgcatcg ggatggaagc agcatatgct ccctttaact ggacccagga
     3181 tgatgatagc aacggagctg tcaaaatcga tgggaccaat cagtatgcca acggatacga
     3241 tgttcaaatc gccaagaaaa tcgctaagga cttaggtaaa aaacctttgg ttgttaaaac
     3301 caagtgggaa ggtctagtcc ctgcccttac ttctggtaag attgacatga ttatcgcagg
     3361 tatgagtcca actgcagaac gcaaacaaga aattgccttt tcgagcagtt actacactag
     3421 cgaaccagtt ttgcttgtca aaaaagattc tgcctacgca agtgctaaat ctttggatga
     3481 ctttaacggt gcaaaaatca cttctcaaca aggggtctac ctctacgact tgattgcaca
     3541 aatcccaggt gctaaaaaag aaacagccat gggagacttc gctcaaatgc gacaagctct
     3601 tgaggctggt gtcattgatg cttatgtttc tgaacgtcca gaagcactga ctgctgaagc
     3661 tgcgaactct aagttcaaga tgattcaagt agaacctggt ttcaaaactg gggaagaaga
     3721 tacagctatc gctatcgggc ttcgtaaaaa tgacaatcgt attagccaaa tcaatgccag
     3781 cattgaaacc atttcaaaag atgaccaagt tgccttgatg gatcgtatga tcaaggaaca
     3841 acctgccgaa gctacaacaa ctgaagagac tagcagtagt ttctttagcc aagtcgctaa
     3901 aattctttct gaaaactggc aacaactctt gcgtggtgct ggtatcactc ttttaatctc
     3961 tatcgtcgga accatcatag gtctcattat tggacttgcc attggtgtct tccgtactgc
     4021 tcctctctct gaaaacaaag ccatttatgg ccttcaaaaa ctagtcggct gggttctcaa
     4081 tgtctacatt gaaattttcc gtggtacgcc aatgattgtt caatcgatgg ttatctacta
     4141 tggaactgcc caagctttcg gtatcaacct tgaccgtaca ctagctgcta tcttcatcgt
     4201 ttcaatcaat accggtgcct acatgactga aattgtccgt ggtggtatcc tggcagttga
     4261 caagggacaa tttgaagctg cgactgctct tggtatgact cataaccaaa ccatgtgtaa
     4321 gattgtccta cctcaggttg tccgcaatat cctaccagca actggtaatg aatttgtcat
     4381 caatatcaaa gatacatctg tattgaacgt tatctctgtt gtcgaacttt atttctcagg
     4441 aaataccgtg gcaacacaaa cctatcaata cttccagaca tttacaatca tcgccgtgat
     4501 ttactttgtc ctcaccttca ccgtaacacg tatcctacgc tttatcgagc gcagaatgga
     4561 catggatacc tacactacag gtgctaacca aatgcaaacg gaggatttga aataatgaca
     4621 caagcaatcc ttgaaattaa acacctcaaa aaatcctatg gacaaaacga agtgctaaaa
     4681 gacatttctc tcactgtcca caagggagaa gttatttcta tcatcggaag ctctggaagt
     4741 gggaaatcaa ccttcctacg ctccattaac ctacttgaaa cgccaactga tggacaaatc
     4801 ctttatcatg gacaaaacgt cctcgaaaaa ggctatgacc tcacgcaata ccgtgaaaag
     4861 ttagggatgg ttttccaatc ctttaacctc tttgaaaatc tcaacgttct tgaaaacaca
     4921 atcgtcgctc agacaactgt ccttaaacgc gaacgcacag aagctgaaga aattgccaaa
     4981 gaaaacctgg aaaaggtcgg catgggagaa cgctactggc aagcgagacc caaacaactc
     5041 tcaggtggtc aaaaacaacg tgtggccatc gctcgtgccc tttcaatgaa tcctgacgcc
     5101 attctctttg atgaaccaac atcagctctc gatccagaaa tggttggaga ggtcctcaaa
     5161 atcatgcaag atctggctca ggaaggcttg accatgattg tcgtaaccca tgaaatggaa
     5221 tttgcccgtg atgtctctca ccgtgttatc tttatggata agggtgtgat tgctgaagaa
     5281 ggtaaaccag aagacctctt cactaatcct aaagaagacc gtacaaaaga atttcttcaa
     5341 cgttatctca tactcaatga aaatcaaaga gcaaactagg cagctagccg caggttgctc
     5401 aaaacactgt tttgaggttg cagatagagc tgacgtggtt tgaagagatt ttcgaagagt
     5461 atcaaataaa aagaaaaggc tgcatcaacc gtgcagtctt tttgctgtcc tcaaaatgaa
     5521 aaggcagatt ctctatctct actacttgaa ggtcaagaat ccaccgttat ccaaagatta
     5581 atcttcaaat ttttcatgat ttttttcata gaaatcaatt aagcctaggg ctgtttcaaa
     5641 tgaaatattt tttacttttg cacgaccctg cgccagagca atgatagaca tttcacgcgc
     5701 attcgtttct ttagagatac ggtagcctgt gattttctta tcacgaaccc agccaacaac
     5761 tgattctact ttttcaaagt ttgacttagc catgtttttc tcctattttc ttctttataa
     5821 tatttaattg tatacgtttt tactactttt gtcaataaaa aaaacatata ttcaacgaaa
     5881 ataattagtt cagaattttc ttacttcctt tttaaatccg ataatatata ggttttgcta
     5941 gcctctacac cataaatatt tgctaataaa aatactgtat tattaccctc ttaaggtgca
     6001 aaattattca agttcttaaa aaatgcttct ctatttccgt aagatagctt atttcttcga
     6061 tttaagaact gaagatgata gttctaacct ttagaaatcc aagccttctc tagctcaaaa
     6121 actcctatct ttcttcctca ataaatcatc tgagagatag gtattcctta tatccttcaa
     6181 attcatcact cctttggata ttgaggtgct agcctagaag cagacacccg attatctaaa
     6241 ccatccttaa tagagatgac aagacagata agctcagtta attacttata tatcttttta
     6301 atatggtata tttgtcaaca aaaagaaatc aaatcatacc ttatactcaa tgaaaatcaa
     6361 agagcaaact aggaagctag ccgcaaattg ctcaaaacac tgttttgagg tttcagatag
     6421 agctaacgtg gtttgaagag attttcgaag agtattaaag acagtatgac tatgcttgtc
     6481 aatagatagg aaatcaaaat gaaggatgga aatctgagcc aaacatcata agtgctataa
     6541 tgaacagaag taagaattgc acgataagtt ttctaaaacc ataggaatcg tcccctttct
     6601 tcatcttcat tatagcacat atacatcagt tgtacaaata atatgatatt tttttattag
     6661 tcctcagaca agcatattat aaagcgtttc attaccattt aagttaatat aagctggatc
     6721 aaaaccttcc attctacgga tcaaacctgc ataatcatgc ttatctgcca aagcgatccc
     6781 aatcaatact gggcctgttc ccttgctagc tcgtttgata tactcaaaac gtgtgatatc
     6841 atcatttggc cccaggatat catttacaaa ctcacgcaaa gctcctggac gctgtgggaa
     6901 attgaccaca aagtaatgtt tgataccatc ataaatcaag gcacgctctt ccatttctgg
     6961 catacggttg atatcattat ttcctccaga aatgatacaa caaatggttt tccccttaat
     7021 atattcagct aaaacctcta aagaggcgat actagccgct ccagcaggtt ctgcgactat
     7081 cccttgctta gagtaaaggt caatcaaggt ttcagaaatc aatccctcat cgacacctac
     7141 caaagtttga atatgttgac gagttgcttc ataggtcaac tgacctacct tttgcacagc
     7201 aatcccatcc gcaaatttat caatttcctt gagtttgact ggacctccag cctcaaaggc
     7261 agctttcatg gaacgcgctc cattcgcctc tactccgata acctcaatct ctggacttgt
     7321 ttccttgata taggtagaaa ccccggcaat gagaccgcca ccaccaacag gaaccaagac
     7381 agcatcaaaa tcaatcgatt cttttcgagc ttcttctaaa atctcataag caactgttcc
     7441 ttgacctgct tgaacatgag catcatcaaa aggatcaata aaggtacgat tttcagagac
     7501 tgtaaattct tgagctgctt tggctgaggc atcaaaggta tctccaacta gtttaatagt
     7561 tacaaaatcc ccaccaaaaa agcgaacctg accaatcttt tgttgtggcg tagtaatagg
     7621 cataaagata gtagcaggaa ttttcatttc attacaagta taggctactc cctgcgcatg
     7681 atttcccgca gaagcgcaga ctaccccacg ttcacgttct tccttgctga gctgggaaat
     7741 ggcataatag gcaccacgaa ttttaaagga gcgaacacgc tgggcatttt cttttttcaa
     7801 ataaatctta gcaccatact tctccgataa ataatgatcg taatccagtg gagtattcac
     7861 aaccacaccg ttcaagacct tgtgagcctt gattatatct tttgaactta acatataaaa
     7921 cctctttttc tataaaaaac agtcactaat gactgttttt tagttattca tctccgaaaa
     7981 cttcagtaac actttcatgg tatttatgag ccatacgaat cgaaaactct ttaggaagtt
     8041 cataacgatt tgtggaaatc caatcatata accattctac caaactttct tcactatcat
     8101 tacgatggaa gataaaatag tttaaaattt ctttatattc tacatcattc aaatccaacg
     8161 tgtctacaaa ttgactacga ggaacaaaat tagaatctaa ttttcttagt tgatctgtca
     8221 attctcccaa ttgtaaatcc aactgaaaaa atagtttttg cagttgccta tcagtttcat
     8281 cacatcctgt cttgatagaa aacaaattgg taatattcat atgatttcaa cccctaaata
     8341 agtacatcta atatcccacg aatagctgaa gctaaagttt tcgcagtcca gtcatttaaa
     8401 cccgattctt tcaatccaga tgcaataatt tgctctattt gatataaacc gccatctatc
     8461 gtctcattta ttctgcgaag aggaccttca atataggata aagcttctcc gaatctaaca
     8521 gctgatttag gtcctaatga tttaccaact atatttgtta atgtttttta tttctcaaaa
     8581 tccatttcgc tatataacga gcagatttag tcgcaccagc tctctcaaac ggagaatgaa
     8641 tttcaagacc ttcttctcta gctatttgtg ccaatttgaa gaattgttca aaggtcatat
     8701 gcaacctacc atcttcaaaa ttagcatcat cataaatgtt aattacagca ttttcatcat
     8761 acgaccaatc tgctttattt tggtctgcta gcactattac cgacggtgta attacattat
     8821 acaactagaa ccaataataa cgatgcaatt tttctcataa tctttttcat aaaatcatct
     8881 ccagcgctat atatttctaa ttagttatag attttgaatg catcatcgtc gtttttacca
     8941 acaaatggca ttgctttacg caattctgca ccaacttttt caatttcaag gttagctgct
     9001 tgttcacggt aagcagtcaa ttttggacgt ccagctttat agtcatttac aaagtcattt
     9061 gcaaatttac cattttggat gtctgccaag acagccttca tattttcttt aacttgttca
     9121 gtgattacac gtggacctga tacatagtca ccgtattcag cagtgtttga aatagattga
     9181 cgcattttct tgaatccacc ttcgtagatc aagtcaacga tcaatttcat ttcgtgaaga
     9241 acttcaaagt aagccaattc tggagcgtaa cctgcttctg tcaagacttc gaaacctgct
     9301 tcgataaggg cagtcaaacc accacaaagt acagcttgtt caccaaacaa atcttcttca
     9361 gtttcttctt tgtaagttgt ttcaagaaga cctacacgag ccgctccaac acctttacac
     9421 cagtccatag caatgttttt agcatttcct gttgcatctt ggtatactgc ataaagagct
     9481 ggaacaccaa atccttcttc gtaagtacga cgtaccaagt gtcccggtcc tttaggagca
     9541 cacatgaaga catctacatc cgcaggaact ttgataaatt caaagtggat gttgaaacca
     9601 tgggcaaatc caactgcgtt tccagcttcc aagtttggag cgatttctgc ttcgtacaat
     9661 tcttgttgaa tttcgtctgg cgccaagatc atgataacat cagccaactt agtagcttct
     9721 actactgtgt aagtatcaaa tccatcttct tttgctttat caaaagattt acctggacgt
     9781 acaccgataa taacgtcacg acctgaatca cgcaagtttt gagcatgcgc atgtccttgt
     9841 gaaccataac cgataacggc gattttttta ccgtcaagtg ctgctacttt aacatctttt
     9901 tcatattcca tttgaactgt catagctttt ctctcttttc tattatttat tgccttttag
     9961 gctggtttaa taaatttaag ttggattttt aatcgcgggt aaatccagtt gcacccgttc
    10021 gagcaatatt gcgaataccg tatgggcgaa tgactcgcaa tagggcttcg ctcttttctg
    10081 catttcccgt catctgaatg gtaatcgagc ttggcgctac gtctaccact gttgcacgga
    10141 aaggttgaat aatcgctaaa atctcagctc tcttctcagc tggcgctgac atcttaacca
    10201 aaatcacctc gcgctccaaa tgaggcttgt ctgtaatatc tcgaatgcga atcacatcaa
    10261 tctgacgatt gagctgtttg atgatttgct ccacttcatc atgagaagca acatcaataa
    10321 taatagtgat acgcgataca ttcggatctt ctgttgctcc aacagagatg ctttcaatat
    10381 taacctgacg acgagatagg acacctgtaa agcgattgag gactcctgaa cgattttgta
    10441 gttttgctgt taacattcta cgcatggaac tgcaccccca acatctcatg attactctta
    10501 ccagccggta ccattggtaa cacctgttcc ttacgagaaa tatctacctc aattagcata
    10561 ggaacatcct cagtgatgac ttcaaggtct tgagccaagg tctcaggatt gtcaaactta
    10621 tagtttttaa taccataagc ctgcgccatc aattggaaat caggaagggt atcaaagacc
    10681 gactctgatg ttctgccttc atagaaggat tcctgccact ggcgaaccat tccaagtgaa
    10741 tgattgttca gcataaccac cttgattggc accttgtaaa tattcaaaat agccaactcc
    10801 tggttggtca tttggaaacc accatcccca acaaacaaga ctacttcctt atctgggtta
    10861 gcaattttag caccgattgc tgctggaatt ccaaagccca ttgttcccaa accacctgaa
    10921 gtcactaact gacgctcatt ttggtaggga taatactgag ctgtccacat ttggtgttga
    10981 ccaacgtctg ttaccacaat ggcatctcca ttcgtcaatt caccaattcg ttcaataact
    11041 gcttgcggtt gaaccacacg ctctttcttg tcataagaac gaacacgatt cttgtcttta
    11101 gtgactttct caatccactt ttcagtattg ttgtgaactg ttggttctgc tagcaacatt
    11161 tgcaaggcct tcttagcatc tccaactaca ggaatgtctg cactgataat cttgccaatc
    11221 tcagctgggt caatatcaat gtgggcaacc ttagcattct tagcgaaagt cttaggattc
    11281 cccgtcaaac ggtcatcgaa acgagaacca atactaatca taaagtccgc ttccgtcatg
    11341 gcaatatttg ctgcgaatga cccgtgcatg cctcccattc caagaaagag tgggtgactc
    11401 gttgcaatcg ttccttgtcc caaaagactg gttaccactg gaatttgata gcgttctgca
    11461 aattcattta gttccgtagc agcctcagca taactaattc caccaccagc taacaagact
    11521 ggctttttag ccttggacaa ttgcttcaag attttcttga tttgcatatc attcggctca
    11581 agagtcggct gataacttgg taaattcact tctggtgaat aaatgaagtc tgtttctaaa
    11641 gcagatatgt cttttggtag gtcaattaca actggccctg gacggcctgt agttgcgata
    11701 tggacagctt ccgtaatgat acgcggaata tcagctgtct cacgaacttg gtaattgtac
    11761 ttagtgattg gcatggtaat tcctacgatg tctgcctcct gaaaggcatc cttcccaatc
    11821 cctgctcgcg ccacctgacc tgtaaagacc aaaaggggaa cgctatcgct catagcatcc
    11881 gcaatccctg taatggcatt tgttgctcct ggtccactag tgacgacggc aacacccaac
    11941 tttccagttg atttggcata accttcagct tcatgcaaac aaccttgctc atggcgccct
    12001 agaatgtggc gaatgccttt aaaattatat atcgcatcat aaaaaggcaa aaccgcacca
    12061 ccaggataac caaagatggt atcaactcct aaatcacgaa gtgtttccaa aactaggtcc
    12121 gaccccgtct taggagattc taaactgatt ttctccattg ttcccctttc tttcctctta
    12181 aaaataactt gttactatca taccattttt tcaaaatttt tcaagataaa agaagaaatt
    12241 ttctgaattt tctattttaa cgtttattta tgaatgttat ttttgttttt attaaaaaga
    12301 taccgatttc atttactaaa aaagaaaaaa gaactgattt ctcagtcctt cattaatctt
    12361 attccacact aaataggtat gggtaaacag gttgttgacc ttggtgaatc tcgacttcaa
    12421 cgtcttcgaa ttcttctacg atttcttgag cgatttcatt ggcaagttct tcgcttccgt
    12481 cttcaccgac atagaaggtt acgatttcac tatcttcatc caacatatgt ttcaaggttt
    12541 cagtcaatgt ttggtgcata tcagggtttg acacaagaat ttttccatcc accataccta
    12601 gattatcgtt ttcatggatt tctaagccat cgatcgttgt atcacgcacg gctgttgtga
    12661 cgcttccgct aacgacatcg ctaagagcag ctgtcatacg ctcttggttt tcttcaatgg
    12721 acttgcttgg atcaaaggca agaagacttg tcataccttg aggaagagtg cgagcctcta
    12781 ccactactgc tggttgctcc aaaacttctg ccgcagattg agctgccatg aagatgttct
    12841 tgttgtttgg caagaagatg atgttacggg cattgacctg ttcaacagcc ttgataaagt
    12901 cttctgttga agggttcatg gtttgaccgc cttcgataac ataatccacg ccttgagaac
    12961 agaagatatc tgctagacct ttaccagcca ccacagcaat caaagcatac tctttttctt
    13021 cagccgactt gataacttga gtagcttctt tctcaacctg tgcttcgtgt tggttacgca
    13081 tattgtcaac ttttaccttg accaagctac catatttgag accttcttgc ataacaagtc
    13141 ctggatcttc tgtatgaaca tggactttga caatttcatc atcgttaaca acgaggagag
    13201 aatccccaag ctcatccaag tagttacgga attcatcgta gtcaaaatct ttagcatagg
    13261 ttggaccttg cttaagagct accatgattt cagtacagta accaaacgtg atgtcctcag
    13321 tcgctacgtg accagctaca gacttatgat gctctacatt gatcatctca ctcatgttgg
    13381 caggagtcgc tacaaagtcc tcagatgcaa tatattcgcc agtaagggct gaaaggaaac
    13441 cttcgtagat gaagaccaat ccttgaccac ctgagtccac aacgccaact tctttcaata
    13501 ctggaagcat gtctggtgtt ttagctagag ctgttttagc accttccaag gctgcgcgca
    13561 tgacttcaac agtgtcatct gtttgctcag cttttttctt agcaccgata gcagctccac
    13621 gagaaactgt caaaatcgtt ccttcaacag gtttcatcac tgccttatag gcaacttcca
    13681 cacctgattg gaaggccaga gccaagtctt gacctgttaa ctcgtcttta tccttgatag
    13741 cttgggaaaa tccacggaaa agctgagacg taatcactcc tgagttccca cgcgcaccca
    13801 tcaaaagccc tttggcaaga atgctcgcta cttctccaac tgtagaagct ggcttgtctg
    13861 caacttcttt agcaccattt tcaatggtca ttcccatatt tgtcccagta tctccatctg
    13921 gaactggaaa gacgtttaat gaattgacat attcagcttg cttattcaag cgagttgatg
    13981 cagcctgcac catttcttga aataagctag tagtaatttt tgacacggtt attctcctac
    14041 aactttgata ttttgaatgt agacatttac agtctgagca gtaattccaa gctggttttc
    14101 caagctaaag gcaacacgct cttgaatgtt ttttgacact tcactaatct ttgttccgta
    14161 gcttaacacg gtatatacat caactgcaat actgccatct tcggctgcct ttacgacgac
    14221 acctttagaa taattttcct tacctagcag ggcttggaaa ttatctttga gggcattttt
    14281 actagccata ccgaccacac caaaaatctc agttgctgct ccacctacga cggttgcaat
    14341 cacttcatct gttagttcga tttgaccatc ttttgtatta atttttacag tcatcctttt
    14401 tacctcaact agttgatact ctattttatc atatttcagc ccaagtgtaa aagcagaatg
    14461 atgtatcagc ggatatttac tctatttttc aaacgatgtt atacccacaa taaaagaaaa
    14521 aagaccctaa ggtctccttt gcttttatta ttaaacgcgt tcaactttac ctgatttcaa
    14581 agcacgagct gaagcccaaa cttttttagg tttaccatcg ataagaacag taactttttg
    14641 aaggtttggt tttacggcac gttttgtttg gttcatcgcg tgtgaacggt tgtttcctga
    14701 tacagtctta cgacctgtaa agtaacatac tttagccatt gtgttttcct cctattagat
    14761 ctaatatagc ggatgtgcta gcaccacata ccgtactatg ttatcacact ttcttgtttt
    14821 ttgcaaggga attggaagat tttttatttg tgtcttaaat caggtcttgc gtgacatttt
    14881 ctgctctcca catgccatcg ttgattaaca gaacaccaga attaaaatta tgtgtataaa
    14941 aatcatctct aactgcagct aagggtatag ccgtcaagtc caaatcccac agctcatcta
    15001 tcgattttct tacaacaata tctgaatcca aatacagtac acgagactcg cttacatact
    15061 ttggaataaa atacctaaaa aagccgcata tgaaagtccc tcaaagggga gacgataacc
    15121 tttcagaata ttactgtcaa tctaaacatt cacaatctca ctattcaaag tctctagtct
    15181 tttttccatc aattggaacc attctcgcgg aaggtcatca ttaaaaacat aaaacttaag
    15241 attataatga tgaacacaaa gagattttat tgttgtttca actttatcca tataagcatt
    15301 atctgcacct aagacaatcg cttttttctc ttttttctct tctttcactt tttatctcat
    15361 ttctttttat tcccatcata tgtttctacg taaccattat tttcgcctat tcgttcgtaa
    15421 aaccatacca gtggagattt tagatgaagt cccattacgg tttacaattt ttacattacg
    15481 acacggagtt ttacaaatcg atttcatttg ccaaacgtag ttagtgaggc agttagctag
    15541 ttcgccaaat agcgactagc gtccaacaat ttggaacttt agttccaatt gttggtactg
    15601 agtcacatct tctcctctaa ctctacgtct ggatacttgt cagcaaacca gcggagggca
    15661 aagtcatttt caaagagaaa gactggttgg tcaaaacggt ctttggctaa gatattgcga
    15721 cttgacgaca tccgttcatc caagtcctca ggcttgatcc aacgaacggt ctttttaccc
    15781 attgggttca taactacttc tgcattgtac tcgccttcca tgcggtgttt aaagacttca
    15841 aactggagtt gacctacagc gcctagcatg tactcacctg tttggtaatt cttataaagc
    15901 tgaacggctc cttcttgcac caattgctca atccccttgt ggaaggattt ttgcttcata
    15961 acattcttag cagaaacttt catgaaaatt tcaggagtaa aggttggcag tggttcaaat
    16021 tcaaacttgt ttttaccaac tgtcaaggta tccccaactt gataagtacc ggtatcgtaa
    16081 accccgataa tatcacctgc cacggcattg atcacattct cacgactttc cgccataaac
    16141 tgggtaacat tagatagttt ggccccctta ccagtacgag ggagattgac actcatgcca
    16201 cgctcaaatt cgcctgatac gatacggaca aaggcaatac ggtcacggtg acgaggatcc
    16261 atgttggctt ggattttaaa gacaaagcct gagaaatcct tgtcataagg atccacaatt
    16321 tcaccgtctg ttttcttgtg accatgtggt tctggagcaa acttgaggaa gatttcaagg
    16381 aaggtctgca caccaaagtt tgtcagggct gaaccgaaaa agacaggcgt caattctcca
    16441 gccagaatag cttcctctga aaactcattc ccagcttcat ttaaaagctc aatgtcatcc
    16501 ttgacttgct cgtagaaagg attgctacca aagagtttgt ccccgtcttc tagactggca
    16561 aaacgctcat cccctttgta aagctctaaa cgttggttat agaggtcata caagccctca
    16621 aaggctttcc ccatcccgat aggccagttc atagggtagc tagcaatgcc caagatttct
    16681 tccaattctt gcaagagatc caaaggctca cgaccgtcac ggtccagctt gttcataaag
    16741 gtaaaaactg gaatgccacg atgtttcaca acctcaaaca atttcttggt ttgagcctcg
    16801 atccccttgg cagagtccac gaccatgacc gcagcatcca ccgccatcaa ggtacgatag
    16861 gtatcttctg agaagtcctc gtgccctggc gtgtctaaga tattcacgcg cttgccgtcg
    16921 tagtcaaatt gcataacaga tgaagtaaca gaaatcccac gttgcttctc gatatccatc
    16981 cagtcagatt tagcaaaagt ccctgttttc ttccctttta ccgtaccagc ctcacgaatc
    17041 tcacccccaa agtagagtaa ctgctcagtg atggttgttt tccccgcgtc cgggtgggag
    17101 ataatggcaa aggtacgacg tttcttaatt tcttcttgaa tattcataag ttctctttct
    17161 ttgattctct atttttcttg tttcaatagc tgagaatgat ttttacattg gattttacca
    17221 ttcctttcaa cattccatta tatcggattt tagcattttt ttcaatttct atttcttttc
    17281 acttccccct cccttattta taggaaaata tggtaaaata gaacagacta aaaatcatca
    17341 tttcacgaaa ggatgcaaga tgaaaattac gcaagaagag gtaacacacg ttgccaatct
    17401 ttcaaaatta agattctctg aagaagaaac tgctgccttt gcgaccacct tgtctaagat
    17461 tgttgacatg gttgaattgc tgggcgaagt tgacacaact ggtgtcgcac ctactacgac
    17521 tatggctgac cgcaagactg tactccgccc tgatgtggcc gaagaaggaa cagaccgtga
    17581 tcgcttgttt aaaaacgtac ctgaacaaga caactactat atcaaggtgc cagctatcct
    17641 agacgatgga ggagatgcct aatgactttt aacaataaaa ctattgaaga gttgcacaat
    17701 ctccttgtct ctaaggaaat ttctgcaaca gaattgaccc aagcaacact tgaaaatatc
    17761 aagtctcgtg aggaagccct caattcattt gtcaccatcg ctgaggagca agctcttgtt
    17821 caagctaaag ccattgatga agctggaatt gatgctaaca atgtcctttc aggaattcca
    17881 cttgctgtta aggataacat ctctacagac ggtattctca caactgctgc ctcaaaaatg
    17941 ctctacaact atgagccaat ctttgatgcg acagctgttg ccaatgcaaa aaccaaaggc
    18001 atgattgtcg ttggaaagac caacatggac gaatttgcta tgggtggttc cggtgaaact
    18061 tcacactacg gagcaactaa aaacgcttgg gaccacagca aggttcctgg tgggtcatca
    18121 agtggttctg ccgcagctgt agcctcagga caagttcgct tgtcacttgg ttctgatact
    18181 ggtggttcca tccgccaacc tgctgccttc aacggaatcg ttggtctcaa accaacctac
    18241 ggaacagttt cacgtttcgg tctcattgcc tttggtagct cattagacca gattggacct
    18301 tttgctccta ctgttaagga aaatgccctc ttgctcaacg ctattgccag cgaagatact
    18361 aaagactcta cttctgctcc tgtccgcatc gccgacttta cttcaaaaat cggccaagac
    18421 attaagggca tgaaaattgc tttgcctaag gaatacctag gcgaaggaat tgatccagag
    18481 gttaaggaaa caatcttaaa cgcggccaaa cactttgaaa aattgggtgc tatcgtcgaa
    18541 gaagtcagcc ttcctcactc taaatacggt gttgccgttt attacatcat cgcttcatca
    18601 gaagcttcat caaacttgca acgttttgac ggtatccgtt acggctaccg cgcagaagat
    18661 gcgactaatc ttgatgaaat ctatgtaaac agccgtagcc aaggttttgg tgaagaagtg
    18721 aagcgccgta tcatgctggg tactttcagt ctttcatcag gttactacga tgcctactac
    18781 aagaaggctg gacaggtccg tacacttatc attcaagatt tcgaaaaagt cttcgcggat
    18841 tacgatttga ttttgggtcc aactgctcca agtgttgcct atgacttgga ttctctcaac
    18901 catgacccag ttgccatgta cttagccgac ctcttgacca tacctgtaaa cttggcagga
    18961 ctgcctggaa tttcgattcc tgctggattc tctcaaggtc tacctgtcgg actccaattg
    19021 attggtccca agtactctga ggaaaccatt taccaagctg ctgctgcttt tgaagcaaca
    19081 acagactacc acaaacaaca acccgtgatt tttggaggtg acaactaatg aactttgaaa
    19141 cagtcatcgg acttgaagtc cacgtagagc tcaacaccaa ttcaaaaatc ttctcaccta
    19201 cttctgccca ctttggaaat gaccaaaatg ccaacactaa cgtgattgac tggtctttcc
    19261 caggagttct accagttctc aataaagggg ttgttgatgc cggtatcaag gctgctcttg
    19321 ccctcaacat ggacctccac aaaaaaatgc actttgaccg caagaactac ttctaccctg
    19381 ataatcccaa agcctaccaa atttctcagt ttgatgagcc aatcggttat aacggctgga
    19441 ttgaagtcga gctagaagac ggtacgacca agaaaattgg tatcgaacgc gcccacttag
    19501 aggaagacgc tggtaaaaac acccacggta cagacggcta ctcttacgtt gaccttaacc
    19561 gccaaggggt acctttgatt gagattgtat ctgaagccga tatgcgttcg ccagaggagg
    19621 cctatgctta tctgacagcc ctcaaggaag ttatccagta cgctggcatt tctgacgtta
    19681 agatggaaga aggttctatg cgtgtggatg ccaacatctc ccttcgtcct tatggtcaag
    19741 agaaattcgg taccaagact gaattgaaga acctcaactc cttctcaaac gttcgtaaag
    19801 gtcttgaata cgaagtccaa cgccaggctg aaattcttcg ctcaggtggt caaatccgcc
    19861 aagaaacacg ccgttacgat gaagcgaata aagcaaccat cctcatgcgt gtcaaggaag
    19921 gggctgctga ctaccgctac ttcccagaac cagacctacc cctctttgaa atttctgacg
    19981 agtggattga ggaaatgcgg actgagttgc cagagtttcc aaaagaacgt cgtgcgcgtt
    20041 atgtatctga ccttggttta tcagactacg atgctagtca gttgactgct aataaagtca
    20101 cttctgactt ctttgaaaaa gctgttgccc taggtggtga tgccaaacaa gtctctaact
    20161 ggctccaagg ggaagtcgct cagttcttga atgctgaagg taaaacactg gaacaaatcg
    20221 aattgacacc agaaaacttg gttgaaatga ttgccatcat cgaagacggt actatttcat
    20281 ctaagattgc caagaaagtc tttgtccatc tagctaaaaa tggcggtggc gcgcgtgaat
    20341 acgtggaaaa agcaggtatg gttcaaattt cagatccagc tatcttgatc ccaatcatcc
    20401 accaagtctt tgccgataac gaagctgctg ttgccgactt caagtcaggc aaacgtaacg
    20461 ccgacaaagc ctttacagga ttccttatga aggcaaccaa aggccaagcc aacccacaag
    20521 ttgcccttaa actacttgca caggaattgg cgaagttgaa agaaaactag acagaacaaa
    20581 accagcccta aggttggttt tttcttctct accaactccc aataactatt ttggctttat
    20641 ttccagagta ttttatggta aaatgaagag taataatatt tattaaagag gtaaaaacat
    20701 gattgaagca agtaaattaa aagctggtat gacctttgaa acagctgacg gcaaattgat
    20761 tcgcgttttg gaagctagtc accacaagcc aggtaaagga aacacgatca tgcgtatgaa
    20821 attgcgtgat gtccgtactg gttctacatt tgacacaagc taccgtccag aggaaaaatt
    20881 tgaacaagct attatcgaga ctgtcccagc tcaatacttg tacaaaatgg atgacacagc
    20941 atacttcatg aatacagaaa cttacgacca gtacgaaatc cctgtagtca atgttgaaaa
    21001 cgaattgctt tacatccttg aaaactctga tgtgaaaatc caattctacg gaactgaagt
    21061 gatcggtgtc accgttccta ctactgttga gttgacagtt gctgaaactc aaccatctat
    21121 caaaggtgct actgttacag gttctggtaa accagcaacg atggaaactg gacttgtcgt
    21181 aaacgttcca gacttcatcg aagcaggaca aaaactcgtt atcaacactg cagaaggaac
    21241 ttacgtttct cgtgcctaat ctctagaaag aggtcattct atgggaattg aagaacaact
    21301 tggcgaaatc gttatcgccc cacgtgtact tgaaaaaatc attgctatcg ctactgcaaa
    21361 ggtagagggt gttcactctt tttcaaacag atcagtgtct gatacccttt caaaactttc
    21421 actcggccgt ggcgtttatc ttaaaaacgt ggacgaagaa ctcacagcag atatctatct
    21481 ctaccttgag tacggagtaa aagttcctaa ggtagcggtt gctatccaga aagctgtcaa
    21541 agatgccgtc cgtaatatgg ctgatgtaga actcgctgct atcaatattc acgttgcagg
    21601 tatcgtccca gataaaacac caaaaccaga attgaaagat ctatttgacg aggacttcct
    21661 caatgactag tccactatta gaatctagac gccaactccg taaatgcgct tttcaagctc
    21721 tcatgagcct tgagttcggt acgaatgtcg aaactgcttg tcgtttcgcc tatactcatg
    21781 atcgtgaaga tacggatgta caacttccag cctttttgat agacctcgtt tctggtgttc
    21841 aagctaaaaa ggaagaacta gataagcaaa tcactcagca tttaaaagta ggttggacca
    21901 ttgaacgctt aacgctcgtg gagagaaacc tccttcgctt gggagttttt gaaatcactt
    21961 catttgacac tcctcagctg gttgctgtta atgaagctat cgagcttgca aaggacttct
    22021 ccgatcaaaa atctgcccgt tttatcaatg gactgctcag ccagtttgta acagaagaac
    22081 aataaaaaga aaaagtgttt gatagatatc aaacactttt tctttgcctc ccactatcta
    22141 aaaaaatgat aatagatata attgtaaaca aaaatccaga taggttttgc atgattgaga
    22201 aagttaaaaa aactatggca gagaatcgtt aatctcagat tgtcggtaga acgataaaca
    22261 agggcaaaaa agaaaccaat cagactataa tataataaac taattggatc tctgtgagat
    22321 agtatcaaat ggctaatccc aaagataagg cctgataaga tgacatctaa atagtacttt
    22381 gacttaggaa agaaggtatt cataaaatac cctctatcaa gagtctcctc aaaaacagga
    22441 ccgatgatta caagcaggac aaaagataag atagtcgata aaaaggttgg ttgtccattt
    22501 gaaagaacca cggtaaaata ctcatcatga atattcctat ggttaatcaa atgagcatag
    22561 cgtgcctaaa aattaccgag aatctgataa accacataag ttgcaaataa ggagaagaca
    22621 aatgaccagt cccagctctt tttctttttt aacctccaaa ttaatagaaa aggaaacttc
    22681 ccactaatcc cactgttaaa ataagagaat agacatcagc tcctaaccct aaaatgatcg
    22741 tcacatacaa tccaattgtt tgtggtaaat aggtagatag taaaataata agcaaaaata
    22801 ttccaaattg tcttagtttc tttgtgtttc tcatcgtact tttttgaaag attaccctgt
    22861 tcggaagccg tacttccaag catctatata agaattaagt gccccttgcc tcatataggg
    22921 agcaaattct ctataatata accatctact atatccatct tcccaaacag caagaccacc
    22981 tgaagtttgc tccaagtcct cagttgaaag aactgtaaat gtttctgtac ctgtcattgc
    23041 aagtaccttc ttaaaataga ttgttgtagg ctcacattta tagtatattt ctttttttgt
    23101 ctattttata gtctatctcc tcaactggca atttttcgac ctgaattgca tttttccata
    23161 aaaaatgaga cctttctagt ctcatttagt cattcttagt attttctaaa tcgttgatag
    23221 cgttcttcca gcaactcttc tagcggtttt tgtgaaagtc tagccagctc cgtttggagt
    23281 tcttttttga cactcttaat tagttcttta ctagaaagtc ctacttcaga aatcacctta
    23341 tccaccacgt ccatttctaa cagttcatgc gaagtgattt tcatcagttc tgctgcttcc
    23401 atggcgcgag taccgtcctt ccataaaatg gaagcaaagc cttctggact gagaatggca
    23461 tagatagaat tttccagcat ccagacacgg tccgcgacag ctagagccag agccccgcct
    23521 gaaccacctt caccgataat aatggcgata ataggaactt tcaggtcact catttccatg
    23581 agattgcgag cgatagcttc cccttgacca cgttcttccg ctccgacacc aggataagca
    23641 cctgctgtat tgataaaggt cacaactgga cggccaaatt tctcagcctg tttcatcaac
    23701 cgcagtgcct ttcggtagcc ttctggatgt ggttggccaa aattccgttt gaggttgtct
    23761 tgcaaactct tgcctttttg gataccaacc actgttacag cttggtctcc aagccaacca
    23821 ataccaccaa caactgcacc atcatcacga aaagaacggt caccatgtaa ttggataaat
    23881 tcatcaaaaa tgcctgtcgc aaagtccaag gttgtcaagc gactctgctc acgcgcttct
    23941 ctgactattt ttgcaatatt catctaggac tccctccatg caatctgact aggctagcaa
    24001 tcgtatctgg taagtctctt cttttgacaa tagcatccac aaagccatgt tctaatagga
    24061 attctgcctt ttggaaatcc tcaggcaagc tttcacgaac cgtattttca atcacacgac
    24121 gcccagcaaa accaaccaag ctctgtggtt cagccagaat gatatcgcct tccatagcga
    24181 aagaagctgt cacaccacca gtcgttggat ctgtcaaaat ggtcaggtaa aagagaccag
    24241 catttgaatg gcgtttaacc gctgcagaga tcttagccat ctgcatgaga ctcatgattc
    24301 cttcctgcat acgggctcca ccagaggctg tgaataggac aactggtaat ttttcgacag
    24361 tcgcatactc aaacaaacga gtgatttttt cacctacaac cgtacccata gaagccatga
    24421 taaaattaga atccataatc ccaagagcca cagtctgacc tttaataaga gcagttcctg
    24481 tcacaacggc ttcatgcaga cctgtttttt cacgcataga tgccagtttc ttttggtaac
    24541 cagggaaatg caagggatcc ttgctttcaa tccctgtaaa caattctttg aaggttccca
    24601 tatcaatcgt caaagccaag cgttcttggg cagaaatacg aaaggtatag ctacagtgcg
    24661 gacagatacg ttcacttccc agatccttct gatagatggt atgcttacag cctggacact
    24721 gggaaaataa ttcatctgga acctctggct tagcttgagg tttttcccta accgaacgat
    24781 tgggattgat tcgaatatac ttatcttttt tactaaatag agccattgat tccccttttc
    24841 ggtttaaact cttaaagtca ttttattctt tttcttgata tttaggtaag aaggtttcca
    24901 tcaagaagga agtatcataa tccccagcaa tgacattgcg atctgaaatg agatcaagct
    24961 ggaaatctgc attggtctgc actccttcaa tctctaattc atagagggca cgttgcattt
    25021 tcatcaaggc gtcaaaacga ttttcgccgt gtactatgat tttggcaatc atactatcat
    25081 aataaggcgg aatggtataa cctggataaa ctgctgaatc cacgcgcaag ccaactccac
    25141 cacttggcag atagagatta gtaatcttac ctggacttgg agcaaagtta aaggctgggt
    25201 tttctgcatt gatacgacac tcgatggcat gaccgcgtag gacaatatct tcttgcttaa
    25261 cagacaaagg ctgacctgcc gcaatgcaaa tctgttcctt aacgatatca acacctgaaa
    25321 caaactctgt tactggatgt tctacctgaa cacgagtatt catctccatg aaatagaaat
    25381 tgctacttgc ttcatcaaga agaaattcaa tggttcctgc attctcatag ccaacaaact
    25441 ctgccgctcg aacagcagca gcacctattt catgacgcag cgtttttccg attgcaatcg
    25501 agggactttc ttccaaaacc ttttggttat tcctttgaag agaacaatcc cgttcaccca
    25561 agtgaatcac atgtccatgc tcatcaccta ggatttgaac ctcaatgtgc cgagctggat
    25621 agataacccg ttctatgtac atggcaccat tgccataatt ggccttggcc tcactagagg
    25681 cagtttcaaa ggcagaaacg aggtcatctg gtttttcaac cttacgaatc cctttaccac
    25741 ctccacctgc tgaagccttg agcataacag gatagccaat tttttcagca acaatcaaag
    25801 cttcttcaga gttatgcact tctccatctg aacctggtat aacaggcaca cctgctttaa
    25861 tcatctgagc acgcgcattg atcttatccc ccatcatatc cataacatga ccagatggac
    25921 cgataaactt gatacctact tcttcacaca tggtcgcaaa tttggaattt tcactgagaa
    25981 atccaaaacc agggtgaata gcttctgcct cagtcaagac tgcagctgat agaactgcat
    26041 taatattgag ataagactct gttgccttgc caggaccaat acaaactgct tcatctgcca
    26101 acagcgtatg aagagcttcc ttatcagcag ttgaataaac cgctaccgtc gcaatcccca
    26161 attcacgtgc cgcacggata atacgaaccg caatttcacc acgattggca attaaaattt
    26221 ttcgaaacat ggagaacctc cttagttccc aattgcaaaa gtaagggtac cactggctgc
    26281 aagcttgcca tccacttcag cctttgcttc aaccacagct atggtgccac gacgttttac
    26341 aaaagtcgct gtcataacca attggtcgcc tggtacaact tgcttcttga acttaacctt
    26401 atccatacca gcgtaaaaga ccagttttcc tttattttca ggttttgata actccaacac
    26461 accagcagtt tgcgccaagg cttccataat cagaacacct ggcataactg ggtattgagg
    26521 aaagtggccg ttaaagaaag gctcgttgat ggtcacattt ttgatagcaa caatggtatc
    26581 ctcgctcacc tccaagacac ggtccactag aagcatagga taacggtggg gaagggcttc
    26641 tttgattcct tgaatatcga tcatttgata cgtaccaatc ctttaccaaa ctcaaccatt
    26701 tcttcgttag agacgagaat ttccgttacc acaccatcct taggagctgg gatttcattc
    26761 atgactttca tggcttcgat aattaccaat gtttgacctt ttttgacact atcaccaact
    26821 gtaacgaagg caggtttatc tggtccagca gccaagtaaa ccactccaac aagtggactc
    26881 tctacaagat ttccctcact agccacactt gcttcagctg gagctggaac ttcttctgct
    26941 acagtctctg ctggagcaga tgtaggagct actggactcg gtgttgctag aacgggtgct
    27001 ggagcgactt gagttgcaac ttcaggcaca ggtctcgctt cattcttgct aaactgcaac
    27061 tcatccgtcc catttttata agaaaattct ctcaaacttg actggtcaaa ttgagtcatc
    27121 aagtctttaa tatcgtttaa attcatactt atctattctc ccaacgtttg aaagcaagaa
    27181 ctgcattgtg gcctccaaaa ccaaaagtat ttgaaatagc gtatggaatt tctttctcca
    27241 agccttgtcc ataaacgaca ttagcttcga tataatctga tacttcactt gtcccagctg
    27301 tcattggtac aaagttatga cgcatagctt cgatggtgac gatagcttct actgcacccg
    27361 cagcccccag caaatgtcct gtaaaagact tggttgatga tacaggtact tccttaccaa
    27421 gaacagctac gatagcacca ctttctcctt tttcattggc aggagttgac gttccgtgag
    27481 cattgacata ggctacttgc tctggagaaa tctcagcttc ttccaaggct agtttgatgg
    27541 ccttgatagc tccctgacct tctggatgtg gagaagtcat gtggtaggca tcacaagtat
    27601 ttccgtaacc aaccacttca gccaggatag tagctccacg tttttcagcg tgttcaagac
    27661 tttctagaac caacatccct gaaccttcac ccataacaaa cccattgcga tccttatcaa
    27721 atgggatcga agcacgagtt ggatcctctg tagtagagag agctgttaag gcttggaaac
    27781 cagcgatggc aaaaggtgtg atagaagctt ctgttcctcc caccaacatc acatcttgga
    27841 aaccaaactt aatggagcgg aaggcatccc caatcgcatc atttgatgaa gagcaggcag
    27901 tattgataga tttacaaaca ccgtttgcac caaaacgcat ggctacattc ccagaagcca
    27961 tatttggtaa agcttttgga agagtcattg gtttgacacg tttgggtcct ttttcatgaa
    28021 ggcgaagtac ctgatcttca atttccttga ttccaccaat accagatgca acgataacac
    28081 caaaacgatc cctattaaga gcctctacat caagattggc atgatttaca gcctcttggg
    28141 ctgcatacaa ggcatataaa gaatagttat caaaacggtt ggtatctttt tttacaaagt
    28201 atttatcgaa cggaaaatct tggatttctg ccgcattatg cacatcaaag tcactatgat
    28261 caaattttgt aatgccacca atgccgattt tcccagttgc taaactattc caaaattctt
    28321 ctggtgtatt tccgattgga gatgttactc cataacctgt taccactact cgatttagtt
    28381 tcattctttt cacctctagc tttcgctaca tacttaagcc accatcaatg gcaatcactt
    28441 gaccagttag ataatcttgg cctgctaaaa atactgtcaa atctgcaacc tgctctgcct
    28501 gcccaaattc tttcatcgga atctgagcta gtgtagcttc cttaatctta tctgataaga
    28561 tagctgtcat atcagactca atcattcctg gagcaatcac attgactcgt atattccgac
    28621 tagcgacctc gcgtgccaca gacttggtaa agccaatcaa gccagcctta gaagcagcat
    28681 agttagcttg accaatattc cccatcaaac caacaacact agacatatta atgatagcac
    28741 cttctctggc tttcatcatc ggtttcaaga ctgattgtgt catattaaag gcaccagtca
    28801 gattgacctt gagcactttt tcaaaatctg cttctgtcat cttgagcata agagtatctt
    28861 gggtaatccc tgcattgttg accaaaacat ctactgaacc cagttctgca atagcttgat
    28921 caatcatacg cttagcgtct gcaaaatctg atacatctcc tgaaatggga accaccttga
    28981 taccatagtt tgaaaactca gcgagcaatt cttctgagat tgccccacga ctgtttaaga
    29041 caatgttggc tcctgcttga gcaaacttgt gggcgatggc aagaccaatt ccacgactcg
    29101 aacctgtaat aaagatattt ttatgttcta gtttcatttt tttcctttca aaacttctac
    29161 ttattttagt ctatttttct aaaagtgcta ctaaactcgc ttgatcttcc acatgagcta
    29221 agtgagcagt ttgatcaatt tttttaacaa aacctgacaa gactttcccc ggtccaatct
    29281 cgataaagtt gcttatgcct gcttcttgca tgaccccaat actttcatag aaacgaacgg
    29341 gttccttgac ctgacgcgtc aagagctgag caatgtcctc tttttgcatc acagcagctt
    29401 ctgtattgcc gactagggga caagtaaaat ctgaaaaact tacctgagct agagtttcag
    29461 ctagtttctg gctagcaggc tcaaggagag cggtgtgaaa gggacctgac accttaagag
    29521 gaatcaagcg tttggcacct gcttcttgca aaagttcaac cgctcgatca actgcaacca
    29581 cttctccagc aatgacgatt tgtgcaggtg tgttatagtt ggctggagta accactccaa
    29641 gttcagaagc tttttgacag gcttcttcaa tgacctctac tggcgtattg agaactgcta
    29701 ccatcttgcc agagtcagca ggagccgctt cttccatata ggctccacgc ttagctacca
    29761 aggcaaccgc atcttcaaaa tccaaggcgc cgcttgccac caaggcagag tattctccaa
    29821 gagacaaacc agcaaccata tcaggctgat agcccttttc ttgcaataaa cggtagatag
    29881 caaccgaagt cgctagaatg gctggttgcg tatagcgggt ctgattgagt ttgtcttctt
    29941 ccgtatcgat gagataacgt aaatcataac cgagcacctg actcgctcga tcaatcgttt
    30001 ctttaacaat cggatactga tcatagaaat cccgtcccat ccctagatac tgggcacctt
    30061 gaccagcaaa taaaaaggct gttttagtca tttcttacaa ctcctgccca gcgagaggct
    30121 tcttcttgaa ttttcttagc ggctccgtaa tacaaatctt ttaggatttc ttcagctgtt
    30181 tcttctttag aaacaagccc tgcgatttga cctgccatga cagagccacc ctccacatca
    30241 ccgtgaacaa ctgctttggc tagggcacct gctcccattt gttcaaagat ttctaaatca
    30301 ggatcttcct gcttaaaggc atctttttca gccagttcaa aatctctagt caactgattt
    30361 ttaatagcac gaacagcatg accaaagtgc tgagctgaaa tcgtagtatc aatatccctt
    30421 gcttttaaaa ttttctcttt gtagtttgga tgggcattcg actcttttgc aactacaaac
    30481 cgtgtcccca cctgtacagc ctctgcacct agcataaagc cagccgcagc accttcacca
    30541 tccgcaattc ctcctgcagc aataacagga atagatatag ctgtggctac ctgtcgcacc
    30601 aaggtcatgg ttgttaattt accgatatgc cccccagctt ccattccttc tgcaataaca
    30661 gcgtctgcac cgattttttc catgcgttta gctaaagcga cactaggaac aacaggaata
    30721 acgattatcc cagcttcatg gaaacgttcc atatacttgc ttggatttcc tgctcctgtt
    30781 gtgacaactt taacaccttc ttcaataacg agatccacga tatcttccac aaagggagat
    30841 aagagcatga tgttgacccc aaagggttta tcagtcaatg atttgatttt atcaatattg
    30901 gccttgacaa cttctttcgg ggcatttccc ccaccgataa ttcctaatcc tccagccttg
    30961 gaaacagccc ctgccaaatc accatcagca acccaggcca tccctccttg gaaaatagga
    31021 tagtcaatct tcaataattc tgtaatacgc gttttcatag tgcctccaac cttccttgct
    31081 tacgtaatag ttcgatttca ccataatttg acagtcaaac tattacctaa acaagaggga
    31141 gtgggtttct ccctactcct tctactaata ttctgcttat tttgcttgct cttcaacgta
    31201 agcaaccaag tcaccaactg ttttcaagtc attttctgct tcgatttgga tatcaaaagc
    31261 atcttcgatt tctgagatta cttggaacaa gtccaatgaa tctgcgtcca aatcatcaaa
    31321 agttgattca agtgttactt ctgatgcgtc ttttccaagt tcttcaacga taatttcttg
    31381 tactttttca aatactgcca tgataggact cctttaaaat aaatagtttt tttataacaa
    31441 tgtgttcacc acatgattac ctaaattgta agaatgagcg tgccccaggt caagcctcca
    31501 ccgaagcctg atagaagaac agtttggcta ccatctaaag ggatgagacc ttgttctaca
    31561 cactctgaaa gtaaaatcgg gatactggct gcactggtat tgccatattc catcatatta
    31621 gctggaagtt tggctcggtc aacaccaatt tttctagcca tcttatccaa aatacggtta
    31681 ttggcttgat gaagtagcag ataatccaag tctgtcacct ctataggaga ttcatcaata
    31741 gtctgcttga tagacttggc tacatctcga atggcaaaat caaagactgt gcgtccatcc
    31801 atcttcaaaa atgaatctgc actttcttga tctgaaaatg gagaatgcaa acctgaatgc
    31861 ccataagtta aacactcgct gcgacttcca tcgctattga gactctcagc taagaaatgc
    31921 tcttgctcgc tagcttctaa caagacacca ccagcaccat ctccaaacaa cacagctgtt
    31981 gatcgatccg accaatcgac tgccttagag agggtttcac taccaatcac caagcctttt
    32041 tgaaagcgac cagaagcgat aaacttttca gcagttgaaa gagcaaatac aaatccactg
    32101 caagccgcgg ttaagtcaaa agcaaaggct ttattagcac caatattagc ttgaacacga
    32161 gcagctgtag agggcatcat cgaatctgga gtaatggtag ctaggatgat aaaatccagt
    32221 tcttctcctg ttattccagc ttttgccatc agtttcttag caacctctgt agccaaatca
    32281 ctggtagatt ctgttcttga aatatgcctt tgtcgtattc ccgttcgact tgaaatccac
    32341 tcatcattgg tatccataat ctgagccaag tcgtgatttg taaccacttg ctctggcaca
    32401 taatgagcaa cctgacttat ttttgcaaaa gccattattt caaatcctcc aaaaattggt
    32461 aaagattagt caaaccttta cccatgacag caatttcttc ctcgctcatg ccatcaataa
    32521 ttttttctac catggccttg tggaagcgtt tatgcagtct atgaatcaag cgacccttct
    32581 ttgtcaaatg cagatgcacc acacgacgat cctgttctga ccgaactcgc tcaatgtagc
    32641 ccttacgctc taaattgttc aaacttgtcg taacagttcc aagagttacc atcaactctt
    32701 ttgacacttg acttggagtc acatctggag ccttaccgat gacatcaatc gtatgcattt
    32761 ctttgatgga gatatcctta aaacgactac ctctcaagtt cacttcctca attacaagga
    32821 cattgttaaa tatagatgtt aaatattcat tgattcgttg gtagtccatt tttcatatcc
    32881 ctccttcttc aaaaaacttt tacaatcaaa acatttgaca gaaagaatta tatcaaaatt
    32941 caaagaatga tgcaagtatt ttttattttc ctgtaaattt aggtcttctt ctctccgaat
    33001 gagctcgcac tccttctttg aaatcctctg tttgagctaa ggatttctgt aggttcagtt
    33061 ctaaagtagc gtaaccctgc cagtctttaa attggctctc ccaaaccaac ttcttaatgg
    33121 cagcatagga attacttgaa gcacgtctta attttttaag aagctgttct ctcgtctttt
    33181 caagtttttc agcttcagaa acgcggtaaa ccaaccccca ttctagggct ttttctgccg
    33241 ttaaagcctc tcctgtcata gctaattgag cagcacgcgt cacaccgata ctgcggctca
    33301 agagatgaat tccccctgca tctggagcca aaccaacacc aacaaaggct tggataaact
    33361 tagccttatc cgtcgccaaa cagaaatctg ccgcaacagc catattcgct gcggcacctg
    33421 caacagcacc gtcaacttcc attaaaacag gtttggctat ttgcttgatt ttataagaaa
    33481 tcgtattgac caactctgcg atttttgtca atgatggaat atcatcctca tccactgccc
    33541 gcttcatctc taccaaatct cccccaactg agaagacctt tccattggca ttgattaaga
    33601 taaaatgcac agctggattt tcttctgcca aagtcagagc ttctaaaatc tcctcacaca
    33661 tgggaatatg aaaaccattt gcgacctcag gacggttcaa ggtaaggatt gccaagtcct
    33721 cttcaagctg ataaataatg tgttccatca gggctccttt ttattttata agcagtttat
    33781 actcttcgaa aatctcttta aaccgcgtca gcttccatct gcaacctcaa aacagtattt
    33841 tgagctgact tcgtctagct tcttagtttg ctctttgatt ttcattgagt gttaaattat
    33901 ttcactgtca aagtatatct tttttaggag cagaaagcaa gaaaaaatcg actgaaagtg
    33961 tctcagccga taagaaaggc tcgctttagg ctagaaagca tcttattttc ttcattgaaa
    34021 aaagcctttc tttctgctat aatcgtataa aatacttact ttaggagttc ttatgaaagt
    34081 tgttaaattt ggaggtagtt ctcttgcctc tgctagtcaa ttagaaaaag ttttaaacat
    34141 cgtcaaaagc gattcagagc gtcgttttgt agtcgtttct gcgcctggta aacgcaatgc
    34201 tgaagatact aaggttacgg atgccctgat taaatactac cgcgactatg ttgcgggtaa
    34261 cgatattagc aagagccaaa gctggattat cgaccgctat gctgctatgg ttagtgaatt
    34321 gggactaaaa ccagctgtgc tagaaaaaat ttctaaaagc attcacgcct tggccactct
    34381 tcctattgaa gaaaatgaat ttctctacga tactttccta gcagccggtg aaaataacaa
    34441 tgccaaattg attgctgcct actttaacca aaatggtatc gatgcacgct atatgcaccc
    34501 tagagaagct gggattgtgg tcacaagtga acctggtcac gctcgcatca ttccatcaag
    34561 ttatgacaag attgaagaat tgacaaacac caatgaagtc cttgtcattc ctggtttctt
    34621 tggtgtcact aaggaaaatc aaatctgtac tttctcacgt ggaggttctg atattacagg
    34681 ttctatcatt gctgctggtg tcaaagctga cctctatgaa aactttacgg acgttgatgg
    34741 tatctttgca gcccaccctg gtattatcca ccaaccacac tcgattcctg agttgaccta
    34801 ccgtgaaatg cgcgagttgg cctatgcagg cttctcagtc cttcatgacg aggctcttct
    34861 tcctgcctac cgtggaaaaa ttcctctggt tatcaagaat accaacaacc ctgaccatcc
    34921 aggtactcgt atcgttctaa aacacagtaa tgatgaattt ccagttgtgg gaattgctgg
    34981 tgactcaggc tttgtcagca ttaacatgtc gaaatacctc atgaaccgtg aggttggatt
    35041 tggccgcaag gttctgcaaa tcctggaaga acttaacatc ggttgggaac atatgccaac
    35101 aggtatcgac gatctttcta tcattctccg ttctcgccaa ctaactccca tcaaggaaga
    35161 agaaatcctg cgtcagttgg ttcaaaaggc taaagtagat catgcagaaa tcgaacacga
    35221 cctttctatc attatgattg ttggtgaaaa aatgaagagc catatcggag tgactgctac
    35281 tgcgacacgc gctctatctg aaaacaaaat caacatccag atgatgtctc aaggttctag
    35341 tgaagtttct attatgtttg ttgtcaataa agaccaagag aaagcagcaa ttaaagccct
    35401 ctacaatgcc ttttttggag aaagtaagga agactaagca tggcccaatc acttaacaaa
    35461 acagtactcc tcagtacgac aggcacttcc tacctctcta tcgctgggaa agttgggaaa
    35521 ttccttgtcg gagatcaggc tttggaattt tacccagatg tcaatgtcga acaatttatc
    35581 cagattcctt ggagccatat caatcagatt ggagccaatg tcactggacg caaaatcagc
    35641 cgccacttcg aagtctttac agacaaagga aaattcctct ttgcttcaaa agactcaggt
    35701 gccattctca aaattgcacg cgaaaaacta ggcaatgaca aggtcgtcaa acttccgacc
    35761 ctgattcaga caattagcca aaaatttaaa aatctatttg caaaaaagta gaaactttag
    35821 tataatcata gcaacggata agtaggttat cttcttcttt cagaaagtct gcgggtactg
    35881 cgagcagata ggggggatag gtgaaattct accgttagta acaattacat acacaatcaa
    35941 gtgcacacct gtgaagttgg atggaaccgt ggccctgcca ctccaacgtt ttgtcaggcg
    36001 tgcttttttc ataaaggagt tcttatgtta gatatcaaac gtattcgtac agattttgaa
    36061 gctgtcgcag aaaaattagc tacacgtggt gtagatgctg ctgtcttgaa tgaaatgaaa
    36121 gaaatcgatg ctaaacgtcg taacatcttg gtcaaggttg aaactctcaa agcagaacgt
    36181 aacacagttt ctgctgagat tgcccaagct aagcgcaaca aggaaaatac agatgacaag
    36241 attgctgcca tgcaaaatct atctgctgag gttaaagcct tggatgctga attggcagaa
    36301 atcgatgcta aattgacaga atttacaacg actcttccaa atatcccagc tgacagcgtt
    36361 cctgttggga ctgacgaaga cgacaatgtg gaagttcgcc gttggggtac tccacgcgag
    36421 tttgacttcg aacctaaagc tcactgggat ctcggtgaag accttggtat ccttgactgg
    36481 gaacgcggtg gtaaggtaac aggcgctcgc ttcctcttct ataaaggcct cggtgctcgt
    36541 ttggaacgtg ctatctacaa ctttatgttg gatgaacatg gaaaagaagg ctatactgaa
    36601 gtcatcacac cttacatagt caaccatgat tctatgtttg gtactggtca gtatccaaaa
    36661 tttaaggaag atacttttga actcagcgat accaactttg tcttgattcc aactgctgaa
    36721 gttcctctga caaactacta ccgtgatgaa atcttagacg gcaaagatct tccaatctac
    36781 ttcactgcca tgagtccgtc attccgttct gaggctggtt ctgccggtcg tgatacgcgt
    36841 ggcttgatcc gtttgcacca attccacaag gttgaaatgg tcaaatttgc caaaccagaa
    36901 gaatcttacg aagaattgga aaaaatgaca gccaacgctg aaaacattct tcaaaaactc
    36961 aaccttccat accgtgtcgt tgctctctct actggagata tgggcttctc agctgcgaag
    37021 acttacgact tggaagtgtg gattccagca caaaacaatt accgtgaaat ctcaagctgt
    37081 tcaaacacag aagatttcca agcccgtcgt gcccaaatcc gttaccgtga tgaagcagat
    37141 ggcaaggtga aactccttca taccttgaac ggctctggac ttgcagttgg acgtacagtg
    37201 gctgcaattc ttgaaaatta ccaaaatgaa gatggttctg tgaccatccc agaagcactt
    37261 cgtccataca tgggtggagc tgaagtcatc aaaccataaa aaataaggtt tagctatttc
    37321 tagctagacc ttttttcgta accaaatcag ataagcacct agtacaaaga ataaaatagt
    37381 taggcatata atggtttcag ccaataccag gtaatccaga aatggaagtt tcaaaattcc
    37441 ctgagccatc ttgagcgagg tcgctgtgat aatggttggg aaggtgaggg ctgagaaggc
    37501 tggttgaaaa ccttgtttta aaatgttggg cagacgagtt aaaacaaaga aaaagaagga
    37561 ttgagaagcc aaaatcatga caatcaagac ccaagtcggc aggctggttc ctcctactcg
    37621 aactagagaa gccaagagta gagagaaagg agcacagtag attccttctt gtccaagcaa
    37681 ggctagtggg agtggatgtt tctttaaatc gctataaata aggggataga gatagaaggt
    37741 caagagaaaa ccaaaactca aggtcgcata ggcaatttcg ataataccta ccagaggata
    37801 ggtcaaggca gccactgcta tccccacata gagaaccgtc caacttggag tggcatgaac
    37861 cctccgccct gaacaagcaa acttgatggt aaaaccagca atcaaggtca aatccaagag
    37921 aaatgaaaac caccaaatcc cttgtgctac caaaggaaga taagagaata cgcgaaagac
    37981 ataggtcgat aaaatcatcc cagccatagg aaaggttgcc attcctgaca aaagaggggg
    38041 cttggtcaat tcttgcttgg tttctttcca attaaagaga tgcagaatta gaaagtaaat
    38101 ccataaaacc aaaccagtca gactaaaaag atgggataga accggcaacg tatctaaaat
    38161 aagatttcca gctcctgcca aacctagcaa acaacctgaa aatactaagg ggagtttttt
    38221 catcctaacc tccaataatc atgttagttt cagtataaca taaaagcgct taaatgagga
    38281 tttaaaaaaa cgaagtccgc ttatttcaga cttcatttta ctcagatatg aattaggcat
    38341 aaggttgcaa ttctggatta attggtgtat tagctaagtt gttggcatag ttacagagga
    38401 ttgctaggct gacaccaaaa accacatcca aggcattttg ttgagtgtag ccagcttcta
    38461 aaaactcaga caaggcttca tctcctacac gacccttggt attgataact gccaaggtaa
    38521 acttagctag ggtatccaat ttaggatctg tttcaattgg agtacgattg cgaagagctt
    38581 gaatcaagtc atcattcatc tggatttgtt tgatggaaaa ggctgtgtga cctgcgacac
    38641 agaaggcaca accattggtc acggctgccg tgatttgcac cacttcacgc tcaacgggtg
    38701 tcaggctgtt gcgacggtgg atagatgaga caatttggta ggcttctaaa acagtcgggg
    38761 cattggccaa gagaccgatt aggttgggaa tatagccatt gttgtctttt tctactgttt
    38821 caagaatttc tttcacttct gctggtgctg actctactgt atggatagta aatgttgtca
    38881 taagatacct cttttcttat tattgacact aatattattg gaaaatctta taaaatcctg
    38941 attcctaagt ttatctaaga taaagcttta ttctctcata agattttcgt tgttatatta
    39001 gtttatcaca cttccaatca cttgcataat atatattata tatcaggctg ataaaaatta
    39061 tttataggca aaaaaatcac acgagctgtg tgattccatt atttgtcaaa atacttttta
    39121 gtttcagcaa taacgactgg cgacaagacc aagagggcaa tcaagtttgg cagagccatc
    39181 aaggcgttaa cgatatctgc gataatccag accatatcca actcgataaa tcctcctaac
    39241 aagaccatga gcacaaaaaa cacacggtag agccagataa agcgagcccc aaagaggaac
    39301 tcaaaacagc gttctccgta atagttccaa cctagaatcg ttgtaaaggc aaaaagtaca
    39361 aggaagatgg tcaagagggc aggcccaaag tgtgaaaaga ctgttgagaa agctgactga
    39421 gtcaaggcaa ccccattcaa gtcaccactc caaactccag ttaccaagat ggtcaaacca
    39481 gttagagtac aaatgatgag ggtatcaata aaggttcctg tcatggaaat caaaccttgc
    39541 tctactggtt catttgtctt ggcagctgca gctgcaatag gagcagaacc cagaccagat
    39601 tcgtttgaga acacaccacg cgccacacca ttttgaatag ccatccgaac gctagcacca
    39661 gcaaatccac ctaccgcagc aaggggacta aaagctgagg taaagactaa agcgattgtg
    39721 ccagggattt ttccgatatt aaagaaaata actgtaagag ttcctaagat ataaatgagg
    39781 gccataaaag gaacaacagt agttgaaacc ttagaaatag acttgagtcc accaaagact
    39841 gcaatcgcta caaagacaga caagacgaga gctgtgatgg ctggcgaaat cgtcgttgta
    39901 ttttggatag attctgtaat cgagttgact tgggtgaagg ttccgattcc caagagagca
    39961 accaatactc ctgctactgc aaacaaaaca gcaagtggtc gccacttttc tcccatccct
    40021 agaaggatat agtgcatggg acctcccgct actgcaccat ggtcgtcctt ggtgcggtat
    40081 ttgatggcca agagtccttc cgcatacttg gtagccattc caaagaaagc cgccatccac
    40141 atccaaaata gagctcctgg tccaccaacc ttgatagccg tcgcaactcc tatgatattt
    40201 cctgttccaa cagttgatgc caaggctgta cacagagctg caaaactgga tacatcacca
    40261 tgtcccttat cctggataaa aataagctga aaggccttgg gcagacgcaa aacctgcaag
    40321 agtcctagcc gcatggttag gtaaatccct gttccgacca ataaaatcaa gaggggcggt
    40381 ccccaagcaa aagcatcgat tgatttaagc aattctaaca tttccttctc ctatcgtttc
    40441 aaccccaaaa gaaagagcac atgcaagata catgtactct ggaatgctta gataaatgct
    40501 aaaaagcggt ctatcctagc tctgtccttt tacctgagag tttgagcagt tgcctgcctt
    40561 gccccttcgg tgcctttacg gtctctccag agttccgtcc atttacagtc atggaaaatc
    40621 aaacgattcc ccacttctat taaacttcat tcggtgttgg tatttaattg attctaattt
    40681 tacaaaaaat gttggctttt gtcaatgtgt ttattagtaa aaattagttc aacagttttt
    40741 actttataaa gtccagaata ctgctatcct ttaaaagtga caatagtcgc accactgcct
    40801 ccagcatttt gtggggcata gccgaaactc ttgacatgtt tgtttctttg caagtatttg
    40861 gtaactcctt cacggatgac tcctgttccg ataccatgga tgatatcaac ttgagccata
    40921 ttgttaagca aggcttggtc gatgaaggta tctagctcat tcatggcttc ttcatagcgc
    40981 ttgcctcgaa gatccagtct agcttgaggt cctcgcccag aagttcgttt cacaacattg
    41041 acctgtttct tcttgactgg tttttcttgc tgggcttgaa caagatcaaa ctctttctct
    41101 tccaaggtca tcttaatcaa gccaacttgg gcttcccagc gaccgtcctt gagttgactg
    41161 gtcaaggtac cacgctgacc ataactgaga accacgatat catctcccac ctttggagct
    41221 cgttttttct tggccttttg aaggacctta tttttagaca agtccacttt ttcaggagcc
    41281 aattttttca acttggcctt ggcttcaatg atttcgtggg gcttgagttg ggatttactg
    41341 tggagatttt tgagaatctg gtcactttca cttagggcca tatccacaat ctcagcagcc
    41401 tgttcacgcg ccttgttaag ctcggtttcc ttttcacgat taagctcgtt gtagagtttt
    41461 tttagcgcac ggttcatctt gagattttct tgctccacct cacggatatt gtccaaacgt
    41521 ttgcggcttt ccagcgtctg ctcttctaat tgctcaatga tacgattgac gtcattgtcc
    41581 tgatcgatct gctgactggc atctcctacg ataacttcag ataggcctag acgtttggca
    41641 atttcaaagg cattacttcg gccaggaaca ccctgcataa agcgataggt cgggcgaaga
    41701 gttgcagtat caaactccat actggcattt tgcacaaagg ctgtctcaat accgtaggcc
    41761 ttgagttctg gatagtgggt cgtcgccatg gtcttgattt gacgcaggcg aaggtcctcc
    41821 agaatagcca tggcaagggc tgctccctct tggggatcag taccagcccc caactcatcc
    41881 aaaagtaaga gtgaatgttg gttgaccttg ccaagaatat ccacgatatt ggtcatatgg
    41941 ctagagaagg tagacaagct ctgctcaata gactgctcat ctccaatatc agcaaagatt
    42001 tcttcaaaaa taccaacacg acttcccttg tctgctaaaa tcggcaatcc tgactgggcc
    42061 atgacctgtg tcaagcccag agttttgagc atgatggtct tcccacctgt attgggacct
    42121 gtaatgacaa tagctgttaa atcttgacca aaatggacat catttgcgac ggcatttttg
    42181 accaaaggat ggcagacatg gagcagttga atctcttgat tttctgacag ctgaggcacg
    42241 actgcttgtc tttcttggat aaatcgaacc ttggcacgaa tcaagtccag atgaccgata
    42301 atccaagcgt cattagcaat ctcagccgca tgagggcgga cacgctcaga aatttcttgg
    42361 agaatgcgaa gcatttcata gcgctcatct gctcgcagac tagcaatttc ttcgctcagt
    42421 ttgactacct cacgtggttc gatatagacg gtgtttccac tagcagaaat atcatgaacg
    42481 acacctgcaa tcttattgcg gtaggtgttt ttgactggta aaacctgacg gccatttctg
    42541 ctagcaacaa ttccttccgt caacatctgc gctttttgct tgagcaagtc ttgtaaaaca
    42601 tcgcgtacct gactctcgct atcatgtatt tttcgacgga ttcgcgccaa ttcttcactg
    42661 gcaaaatttt caatgaaacc cgcatcatta aaggcctgaa gatttccttg taattgcgga
    42721 aaatcatgta atttctcaaa ccaaagggct aattcttcca agctgacatt ttccagattg
    42781 gcataaaaac tttgaagttc tcggctggca agaagcacgc gtttcaagag taggaactcc
    42841 tcgatattga gatccgctcc catctccaac ctcttgcaga ctcctgcaat ttccttagtt
    42901 gagagaatag taaaatgcgg ttgctcgacg aaaagagcct gcatttcttt catctcagca
    42961 aaagcctgtt tgattttatc tgctttggca gtcggagcca gctgtctcaa ttgctccaag
    43021 ccctgctcgg tcaacaaatg aggatcaaac aaggccttga ccttatcgaa ctctaatgtt
    43081 tctaatattt tcttattcat ctttatttcc ttgtctttga atgtctaggt gtggtagctt
    43141 tttacattct gatagattcg agtcaaatct gtaaacaaag ggctaggaaa actcctgccc
    43201 tttttatccg attaaatttg tcacccagat ttgtttgagc caactggttg ttatcggtat
    43261 gctctggatg atgtgttttg cgacgatact cttttcaaga ggattttgta taactgccat
    43321 ggggatggtc gccaagattg tcaaggccat ttgcaagaca aataaggtca ccaacatgga
    43381 caagatacct gctgaaactt ggaacaactt accacccagt tttttgctag gaatcaagtg
    43441 taagagaaga ccaagcaaac gaccaatgct atagaaaatc ccaaatacaa gcaagtagcc
    43501 gatacctgca taaaagacct tatccagctg aaagagttga tccgatggga aaaagaaagt
    43561 cccctgacct tcctgcgaat ttgcataagg gagcaataaa tggaattgct ctccaagccc
    43621 cttataaaac tggccagcca taaaagccga tgccatggct gaaatcaggt aataaacctg
    43681 taagagcagg cctctccgat agccgatata aaatccccaa accaagacca atagaagaag
    43741 gaatgaaatc ataaggaatc ctcaatcttg ctctgttctt gcttacaagt cacaagcttg
    43801 tgacggagtt cttctagctc ttgctcctta tcgtcaaatt caatctcacg gctgagctga
    43861 gttgataaac agttgactgc caacaaaaga gcgattgttt catcatctgc gctaggcatt
    43921 tgttctttaa ttgcttggta tttttctgtc gcaaccttag cgatttcctc cataaaaagg
    43981 ttatcatgtt cgcttgtcaa ggttaacgat tttttcccga atgtaaattt gaatcgattt
    44041 agatttgcca taaaattcac ctcacgatat tataccaaaa ttcgctaatt ttgtcagttt
    44101 ttacaaattt tactgctttt gtggtacaat agaaactatg gcaagtatca cactcacacc
    44161 aagcgaaaag gatattcagg cttttcttga acactatcaa accagtctgg ctcccagtaa
    44221 gaatccctat atccgctact ttttgaaact acctcaagca acggtttcta tctatacttc
    44281 tggaaaaatc ttgcttcagg gtgaaggggc tgagaaatac gctagtttct ttggctatca
    44341 acttgtagag gaaaacaggg ggcaaaatct tcctttaatt gggacagatg aggtgggaaa
    44401 tggttcctac tttggtgggc ttgcagttgt ggctgccttt gtcacatctg accagcacga
    44461 ctttttacga aaactcggtg tgggggattc taagactctg accgaccaaa agatccgtca
    44521 gattgctcct attctcaagg aaaaaatcca gcaccaggca ctccttctct cacccagcaa
    44581 gtacaacgag gtcatcggag accgctacaa tgctgtttcg gttaaggttg ccctccataa
    44641 tcaggctatc tatctcctcc ttcaaaaagg tgttcagcct gagaaaattg tgattgatgc
    44701 ctttaccagt gctaaaaatt atgacaagta cttggcacaa gaggccaatc gtttcagcaa
    44761 tcctatcagc ttagaagaaa aggctgaggg caaatacttg tctgtcgcag tttcttctgt
    44821 cattgcgcgt gatctctttc tggaaaatct tgaaaatttg ggacgagaac tgggttatca
    44881 gctcccaagt ggagctggaa cggcttctga caaggtggct agccagattt tgcaagccta
    44941 tggtatgcag ggactcagct tctgcgccaa attgcacttt aaaaacactg aaaaagcgaa
    45001 aaaacgctta gaaaggtaag ttatgaattc atttaaaaat ttcttaaaag agtggggatt
    45061 gttcctccta attctgtcat tactagcttt aagtcgtatc tttttttgga gcaatgttcg
    45121 cgtagaagga cattccatgg atccgaccct agcggatggc gaaattctct tcgttgtaaa
    45181 acaccttcct attgaccgtt ttgatatcgt ggtggcccat gaggaagatg gcaataagga
    45241 catcgtcaag cgcgtgattg gaatgcctgg cgacaccatt cgttacgaaa atgataaact
    45301 ctacatcaat gacaaagaaa cggacgagcc ttatctagca gactatatca aacgcttcaa
    45361 ggatgacaaa ctccaaagca cctactcagg caagggcttt gaaggaaata aaggaacttt
    45421 ctttagaagt atcgctcaaa aagcccaagc cttcacagtt gatgtcaact acaacaccaa
    45481 ctttagcttt actgttccag aaggagaata ccttctcctc ggagatgacc gcttggtttc
    45541 gagcgacagc cgccacgtag gtaccttcaa agcaaaagat atcacagggg aagctaaatt
    45601 ccgcttctgg ccaatcaccc gtatcggaac attttaagag acctaagagg ccgagaatca
    45661 ccaatctcag cctcttcttc tatcgtgaga agtgattgtt tattgacaaa tactcaacga
    45721 aaatcaaaga acaaactagg aagctagccg taggctgctt aaaacagtgt tttgaggttg
    45781 tggatagaac tgacgaagtc agctcaaaat actgttttga ggttgcagat ggaagctgac
    45841 gtggtttgaa gatattttcg aagagtataa aataaaaaca atcccaactc tcacctattc
    45901 atgcaaagga attttatgga agtttatttt tcaggaacca ttgaacggat tatttttgaa
    45961 aatcccagca atttttatcg catcctcctc ctagaaatcg acgatacgga cgcagaggat
    46021 tttgatgatt ttgaaatcat tgtcacagga accatggctg atgtaattga gggcgaagac
    46081 tatacttttt gggggcaaat tgtccagcac tccaagtatg gagaacaact gcaaatcagt
    46141 cgttatgatc gcgcaaaacc aactagtaag ggcttggtca agtacttttc aagtagccat
    46201 ttcaagggga ttggtctcaa gacagctcag aaaatcgtgg atacctatgg cgaaaatacc
    46261 attgacgaaa ttttgcaaca cccagaaaag ttagaaggca tcgcaggact ctctgccaaa
    46321 aatcgcgagg ctttcgtctc cactctccgt ctcaactacg gaacggagat ggttttgtcc
    46381 aaactagcca actacggcat tcccaacaaa ctagcctttc agattcaaga cttttacaag
    46441 gaagaaaccc ttgatgtggt tgaaaattat ccctaccagc tggttgagga tatcaagggt
    46501 ttgggcttta ccattgctga ccaactagct gaggaactag gcatcgaaag tcaggctcct
    46561 gaacgcttcc gcgccggtct agttcacagt ctttttcagg cctgtatgga aacaggggac
    46621 acctatgttg aagcacggga tttgctggaa caaaccctta ctctccttga gtcttcccgt
    46681 cccgtggaac tagaccccag ccaagttgcc caagagctct cctacctgat cgaagaagac
    46741 aaggttcagc agattgatac caagatcttt gacaacagcc tctttttcgc tgaggaaggc
    46801 atccgcagtc acttggttcg tatccttgaa aaaggaaaac agaagagtca tgatttagaa
    46861 accattcaaa aacatatcac tactatcgag gaagagctgg gaattgagta tgataacatt
    46921 caaaaacagg ctatctgtga tgctatccag aataaggtct ttatcctgac aggtgggcct
    46981 ggtactggta agacaactgt tatcaatgga atcatcgctg tttatgccct gttagaggga
    47041 cttgacttca ggaagaaaag caatctgcct attcttcttg ctgctccaac tggtcgagct
    47101 gctcgtcgca tgaatgaatt gacaggtttg cctagcgcga ccatacatcg ccacttggga
    47161 atgacaggtg acgatgatac cagtcatctg gaagattacc tagatgctga ctttatcatc
    47221 gtggatgaat tctctatggt agatacttgg ctggccaatc aactcttctc caatatctct
    47281 tctaacagta agatcctcat cgtaggtgac agtgatcagc taccttctgt cagtcctgga
    47341 caggttctag cggatctgct tcatattcct ttgattcctc agactcactt ggaaaaaatt
    47401 tatcgacaaa gcaaagaatc aaccatcgtc accctagcta gtcagattcg acagggcatc
    47461 ttgccagctg atttcaccca aaaaaaagct gaccgttcct actttgaaat tgctagtggc
    47521 catattcctg ccaccattga aaaaatctta ggtgccgccc tcagaaatgg tattcctgcc
    47581 cgtgatatcc aagttctggc tcctatgtac cgagggacgg cagggattga tgctatcaat
    47641 cagctcatgc aagacctgct caatccccca caaaaagatc aactcagttt tgaagctcct
    47701 cagtgccact atcgtaaggg agacaaggtc attcatttgg ttaacgatgc tgaaatcaat
    47761 gtctttaatg gggatttagg agctatcaca gacctgattc ctggtaaata caccgaatcg
    47821 aaacaagacg agattgtcat tgattttgat ggtaatgaag tctcttaccc ccgtaacgaa
    47881 tggtacaaga ttcgcttggc ctatgccatg agtattcata agtctcaggg aagtgagttc
    47941 ccagttgtca tcctaccgat tactagtgct agccgacgta tgctggagcg aaatctcatc
    48001 tacacagcca ttacacgtgc caaaagcaaa ctcatcttac taggcgaatt acaagccttc
    48061 gactatgcta cccaacacat cggaactgcc cgaaaaacct atctgattga acgcttcagt
    48121 gatctactgg agaatgttga agaaaagcaa caagctgtct ctgaaacagt cacatcaagt
    48181 gcctctgaac aatcctacat cctaaccgaa gaaaactggg acagcattcc agccatgatt
    48241 gggattacag acacagacct caaagagatt tttggaaaat agtgcatcag aaaaaccacc
    48301 aattcaggtg ggttttctgt ttattaagat tattttactg ttgctgtgct tgtaatcaat
    48361 tcaacagctt ttttgatagt gatatcatgt ttcaacatgt cagctgaaag caagttttga
    48421 acttgtgcaa cttccatgtt gtagtctgct gccaattgct caacttcttt ttggatttct
    48481 tcttctgaag catcaaatcc ttcagctttg gcaactgctt cgataacaag gttagtctta
    48541 gtacgtgact cagcttctgc ttggtattgg ttgtgaaggt cttcttgagt agttccagta
    48601 atttggaagt acatgtcagg gttgatccct tgacgttgca agttcccaag gaattcattt
    48661 actgaacggt gaacttcttc gtggatcatt tcttctggaa gttctacgat ttcagcattt
    48721 tctacagctg tatcaattgc tgcaccttca actgcatctt tgtaagcttc ttctttagca
    48781 gcagccaatt ctttgcggta tttttctttc aagtcagcaa gtgtttcaac ttcttcatca
    48841 atgtcttttg caagttcatc gtcaagagct ggaacttctt tagcttttac ttcgtggata
    48901 gttgtcacga atttagcttc tttacctgca aggtcttctg cttggtagtc ttctgggaat
    48961 gttacgataa catcaacggt ttcgccagct gagtgaccta ccaattggtc ttcgaaacca
    49021 gggatgaatt gacctgaacc aagtccaagt gagaagtttt caccttttcc accgtcaaat
    49081 tcaacaccgt cgatagaacc aacgaagtcg atcacaacag tgtcgccgtc ttcagcagca
    49141 gcttccttga taaccaattc agccaggttg ttgcgttcac gttcgatacg ctcttcgaca
    49201 tcagcgtcag ttacttcttt ttctacatca actgatactt caaggttttt gtagtcaccc
    49261 aattttactt caggttttgt aacaacttca gcagcgataa cccagtcttg acctttttcc
    49321 attgaagtta cgtcaatttt tggttgggca accacttcaa gaccagcctc ttttacagct
    49381 gcttcataag cgtttggcaa aagagcgttc ataacgtctt ggtaaagtga ttcttcacca
    49441 aattttttat cgaagatagg acgtggaagg tgacctttac ggaaacctgg aacattaaga
    49501 gatttcttca ctgacttgaa gacacggtcc aattctggtt tgatttggtc ttgagagata
    49561 gtgaaagtca agacaccacg gtttgtttct ttgttttcaa atgatacaga cattctgtca
    49621 tttctcctta aaatttttta aatacagtct attataacat tttctataaa taaaatctag
    49681 actaatgcag acaattatag acaacaagcc tttttcctaa ctaaaacact cataaagtat
    49741 agacaatttt agactacttt ggatatcttt tggttagtca ttttccaaaa ctaatttatc
    49801 taatttttaa gttatatttg acttcatctt ctcagtaaca tgagtataaa cacttaaaat
    49861 ctttgtttca ttagtataat ctacacgatc cattatcgct gttataggta cttccaattc
    49921 agcaagcaaa cttatatgcg aatatctaaa aacatgagca gtcaatacaa aatcatcttt
    49981 cttaatttca cttttcctaa acctgttttt caaaaagtaa ttgaaacaag ttatcattaa
    50041 gggagaacca ttatttgtaa atatataatc accttcttct aaaagaagat attcttttaa
    50101 aatttctaac actctatcac taataccaat tactctatat gaagctaaac ttttcggact
    50161 atccaaaaac acttcgttat tggacgatta cattatagta aaacgaaata agaacaggac
    50221 aaatcgatca ggacagtcaa atcaatttct aacaatgttt tagaagtaga ggtgtactat
    50281 tatagtttca atctactata caagacgaaa ttgaagaaat ctttccatta taaaacgcat
    50341 attatcaagg tttttaaaca cctaataata tgcgtttttt cctattttaa agacttttat
    50401 ccacctatta tacaaagtta agtatccatc acagtttaca attagccttc attacctaac
    50461 ccattcacca tccttcaaga gagtaacctt taagaaccga ataaataaat ggcaaatttc
    50521 gttcatttaa tttaactgca ctgttaattt gattagctcc atctcctaaa gtatgcactc
    50581 ctactacacg gtgactagca tcataaactg tagatccact agacccctct aaagtatcaa
    50641 cttggtaatc caagaacatg ccatcatcac ttaaaacttg ttttttatct gtatacattt
    50701 gatgaacttt aaaattatat gatggatagc ctgtgatagt cacagttatt cctgtcaaat
    50761 ttttttgact agtaggaaga cccaaagtcc ctaattttgc accaatgggc tcttctagaa
    50821 ttaataaagc caagtcatat tcccttgcat ccttagaatt taaatttcta aattccttca
    50881 aataacgaac ttcctttact ttgatctttc caaatggttc ttgacttgga ctaacagtcg
    50941 gaagaacata aatatcatcc gcttctttcc catagtcatg tctgtagtag ttgtgagccg
    51001 ctgtaattaa cacattatct ttaataaaat tcgcacttcc cctcccttct acattcattc
    51061 catcggctac tccataatac ttagataaaa ccatagctga agtcgaatac ggatactgta
    51121 aagtattatc aattttaatc aaatcatcat taccgataat acttctgatt gcttttggta
    51181 gtatgaacca tatgttggtg aaatctcaga taatgaagaa tcattagatc ctggaccttt
    51241 ttctagtgtc tcacttacct catattcttc acccgtacta gaaataacac tcaaagcaga
    51301 tactgtcgat aactggctag ccaataaagt actcgcaata attgaaatac ccaatttttt
    51361 ataaacagtt ttcttcatta ttgtatcctc ctaatgtaat tatagcgtac tattctaaat
    51421 ttcttaatct actatagaat caagaaatct accaccttct ttaaataccc tccattatca
    51481 cataaacagg taaacttttc aattaatgac tgcgcttttc aatcacgcta gaggtactta
    51541 cttgcttctt tgatactaag ttcagccatt ctttccttgt ttttctcaat aaagcatgtt
    51601 acccaagtgg gattcgtttt ggagtagtct cgcagagtcc agccaatggc tttattgata
    51661 aaaaattctg tttggttcaa gttatgaagt agaatctttt ccattaattg agtattggtc
    51721 ttctcttttc ttaacaactg gtggtcaata gcgacacgtc tcagccagat attatctgat
    51781 aggctccatt ttatactcaa tgaaaatcaa agagcaaact aggaagctat ctgcaacctc
    51841 aaaacactgt tttgaggttg cagatagagc tgacgtggtt tgaagagatt ttcgaagagt
    51901 attaagatta tttcttctag ttcagggtgt tcatacacca aactccctac tactcgatct
    51961 aggatatcta ccgtgtccca ccaggatttt gtcacgacta actgctctag cttaggcaaa
    52021 tcggtttcct ttagataaga ctgcattgct ttcaaatagt tagcagccac atattggtat
    52081 tttctaggct ccttttccca gcaagtgtct gcaaaatccc aatcgataat ctttgttttt
    52141 ttcgcttctg gtaaatattt ttatagagtt tatttctttc aggcaccgca atacctagaa
    52201 aagaaaattg atggcgcata taggcttcca tgggccttgc ttttttagag tcttttgctg
    52261 cttctagctc ctcaagtaaa tctgctaaac tcatctaaaa ctcctcttgc cccaccaaat
    52321 ggtgctgaaa ggcatagaca gccgcctggg tacgatcgct gacttcaagt ttggcaagaa
    52381 tattggacac gtgggtcttg accgtcttga gagagataaa gaggtcatct gcgatgcgct
    52441 gattttcgta gcccttggcg atgagttgga gaacatctcg ctcacgcgca gtcaattctt
    52501 catgaagttc catatgattg cggtggtatt caaccttctt gctaacctct tgctcaatgg
    52561 ccagctcgcc agcagctacc ttactgacgg catgaagcaa ttcatctgca ctagaagtct
    52621 tgagcatata gcctttggca ccagcatcta agactggcat gattttttca ttgtccaaat
    52681 aagaggtcac aatcaaaatc ttggcttcag gccattcttt aaggattgct aaggtcgcgt
    52741 caatcccatt catctcaggc atgacaatat ccatgacaat gacatctgga cgcagttcca
    52801 aggccaagtc aatcccttga gacccgttgg acgcctcacc cacaacttct acatcgtctt
    52861 ggaggtcaaa gtagcttttc aagcccaaac ggaccatttc atggtcatct actagtaaaa
    52921 ttttcatctt tactccttta tcattcctta tctaacaggg gaatacggat atcaactgcc
    52981 agcccttgct tgggagctgt taataactga accgtccctg ccatatcttc aacccgctcc
    53041 ttgatatttc gcagtccata actcaagtcg tctaagcttc ctaaccggaa accaatccca
    53101 ttgtccacca ccttcagttg caattcaaca tctgtctgat agaggtagac atctaggcaa
    53161 gatgcctggg catggcggag ggtattgcta atcaactctt gcaggatacg gaagatatgc
    53221 tcctcgattt tcttaggcaa tttcgtcata ttctgcttga gactaaccct aagatcactc
    53281 ttgtcctcaa gctcttttaa gagaatctga atcccttcta tcaagctctt ctgctccagt
    53341 tcaactggtc gcaaatgcaa gagcaaaacc cgcaaatcct tctgggcagt ttctaaaata
    53401 gctgtgacac tctgcaactg ggtctgcatc ttttctctat ccaatttcaa agcctgctga
    53461 ctgatacccg ataaaataat gtgggccgca aacaactcct gactgactgt atcgtgcaaa
    53521 tcccgagcaa ttcgcttccg ttccttctcg ataatttcct cttcctgatc aaggctatga
    53581 ttttcagctt tttgaagagc ctctgtcaaa aggttaagtt tacctgataa ggacttgaaa
    53641 ctggcatcca aatctggatc tacaacctga actacttctt gccctgccaa taaacgcttg
    53701 agattagcct gcatttttct tagagaaagc tcttcgatcc ctcgccaaaa cagggctaag
    53761 agacaggtca tggacatgct gaaaaccaac aataaaaaga caaatttttc tgttttttcg
    53821 acatcgtaca aaaagataga ccagtcaaaa tcaagtattt ccagcaagct gtgggagaaa
    53881 aaaaagacaa ataggaagga ggtgagagca ataatgacat aggcttgttt tttcatcctc
    53941 taaccacctc cacatcacca atcatagtgg tcaagaaaat cttgacactc ttgttactct
    54001 tgagatagtc ttttgtttct tgatgatagt gttcattgcg gagggctcgc ttgggctggt
    54061 tgaaaaaagt caaatcccca tagagacagt taacgctgag actgacttcc acatctacag
    54121 gtacgatgat tttggtcgtt cctaccatct ttctgaggat aatgacattg tcatgattgg
    54181 ttaagatgac tctctccaga tgaatagtgt ccttgcccat gaagcgaaag agattgatat
    54241 catcaaattg gcaagtctgg tagcttgaaa aatgatgaag atttccaaac caacgatttt
    54301 tctccttctt aaccgtcaca acctcttcaa aaaccaaatt ggtctgctct ttttcctggt
    54361 tcatcatcgg gtaaagaaga aagagactat agataaccgc aacaaaaata gctagaatca
    54421 caaaaggatt gagcataacg atgaaaaaga agagaatggt tgccgctact aaaagaagat
    54481 tattcccctc tttaccagta tagtagcgaa tcaaaagcaa aaagaggaat agtatcagca
    54541 gaaaacgcga aaaatgctct gataccatca aaatcagagc tcctgtcaga agacaggctt
    54601 cgataaataa aaagatttta aattttctca taggttcatc ctctcccttc tattttatca
    54661 caattcaaaa aagtcacctc agtctgagga tggaaaaaaa ggcgctggtt acgccttttt
    54721 catctgatcc tttgcttctt ttaattttcc ataaagaaga tagtctactt tttgtagatc
    54781 tgctatggtg gcacagttaa gggaacacat aatcaagcgt agatctgctt tccagccttg
    54841 gacaatgcca atcacttctt caactgtgta ggtttcaacc aattccagaa cggttcgtga
    54901 caatcccaca gccttagcac caaaaaccaa gcacttaatc atatccagcg gattccgaac
    54961 ccctccacta accaagagtt cgaccttatc tttccattct tgggcattga gaagggcctg
    55021 catggtagac tgaccccatt gattgaggta atcacgctgg ccactacgac ggttttcgat
    55081 ataggcaaag ctggtgccac cacgacccga taggtccact gtacgaacac cgaattcata
    55141 ggctctttcg attgtcttgg catccattcc aaagcccact tccttgagga caataggaac
    55201 gggaatttgc ttgctataat ctgctagatg cgattgccag cttctaaact tcctttctcc
    55261 ctcgggcatg agtaattcct gcatgacatt gacatgcact tgcaatagaa caggattcat
    55321 ctcttctaca gtctgaagtc ctaactcgac aggtttgtcc aatccaatat tggttccaag
    55381 gaggagattg ggatgactag acttgacaga aaaagaatca tccgttggat ttttgagggc
    55441 tgcgctataa gaacccgtta caaataaaat accacaggat tccgccacct gagccagctt
    55501 ttgattgatt tctcttccct tattacttcc accagtcatg gcattgatat aaaaaggaaa
    55561 gtcccacttt cgaccagcaa actctgtcga aagatcgatt tcatccagat tgtaaagagg
    55621 caaggaagaa tgaatcagct ccacctcatc aaagctatta taggaacttt tctgctcaag
    55681 ggcatagagg atatgctcgt ccttacgatt tgtcgtcatg tcctatcctt tcttgatata
    55741 agagctcaat ccccagatcg gcccaacgat tttttaaggt tttggttgat tgcgcatcaa
    55801 aactcagggc gatgccacag tcaccaccac cagcaccact actcttggca acggcctgca
    55861 aatcttgact ggcttctttc aactgtctaa gcaaaggcgt gtaaatatct gtactcaagc
    55921 cttctaaaag cttgctggct acttctactt gctcgataat cttttctgat ttcccctgtt
    55981 ccaaggcttc gaccaaagaa accaccgttt cttttgagga acttaaaaaa ttttgattga
    56041 tattttgctt gatttgctgg accatgtgac tcgatacagc cacttccttg gtccatccca
    56101 ctaagaaatc acattctaaa gttggtttca cttgtgaaat tgaaaagccc caatcacgct
    56161 ccagaactgt cgccaagttt tcttcttcta accaagcagc caccttctgg cgatcaaatg
    56221 actggtagag aaccaaatcc tctgccacaa tacaggcaag gtcgcccatg gaaccattgt
    56281 ctcctcgctt gagcaagaca gcgctagtca gcttgaacaa gagctcctga tcaacagaaa
    56341 catcatacag agccagtaaa gccttgacaa ccaagacaac gacgctgcca ctagaaccta
    56401 gaccaaactt tttcccttct cgttccattt tgccacagat ttctagggaa aaagatctta
    56461 aattctgacc gcgaacagcg aggaagtctc ccatcaaagc aatcgtttct tgaatcaagc
    56521 tgtagtcagg attgggcgtt aagtccactg cgaaatcaaa catatctgaa tagatacggt
    56581 agctgtcaga aaaagcaatc tcagccctca tatagatggg aatatccttt atcaaagcta
    56641 actgccctgg ctctaaaata gcatattcac ctgcccaata gagttttccg caagttttaa
    56701 cagcaatcat cttgactcaa atcctttgtt tttgacacaa tcaagcgata acgctgaccg
    56761 aaaatttctg acaaatgctc caagtctttc tcctgacaaa agaccttaac attgggacca
    56821 gcatccatgg taaagtagca ggcctctcct ttctcacgaa gctggcgaac aaagtccata
    56881 gcctcataag aggcatccgt cagataagaa aaggctggac tagcagtctt tgtcgtagca
    56941 tgcatagcca gggcattttt ctccgttaat tctccaatct tggcaaaatc attttccttg
    57001 agataaatca gcatatcctg atagtccttc tcagactgac gaacccagtc gtcaaaagtc
    57061 gtcgaggttt ccacacaaag tttcatcccg tcacggctag agattggttt tttcttgtcc
    57121 tctagcacca acataatcat agctagtttc aagtctgtct ctacagagta aatttctcca
    57181 ctatccttat cccaggctcc tagcggtcca taaaaactcc gagaagaaga gcctgaggca
    57241 aacttggctt cctgcgctaa ctgacttcta tccaatccaa gcttgaaata agcattacaa
    57301 gccttgacca gggcggacaa accactagaa cttgaggaca ggcccgctgc agtaggcata
    57361 ttgttttgag tatcgatacg gacaaagccc tcaccagctg gacgataacg gtcaataatc
    57421 ttactcatct tggcatgctc gacctcattt tgtagctgac cattgatgta aaattcgtca
    57481 gctattacat tggctggtaa aggcgacaag gtcgtctctg tatacatatt ttccaaagtt
    57541 agagaaatac tgctagtagc aggcaccatc tctttttctt ttttctttcc ccaatatttg
    57601 ataatagcaa tatttgcgta ggaacgtact gtcacaggct ctctatccat gtctgaacag
    57661 ctcctttctc ttctaatctt tctgctagtt cttgtgcgtg tgtcaaattg gttaccaagg
    57721 ctatgataca acctcctagc ccaccaccgc tcatcttggc acccagagca ccatggctaa
    57781 gagtcgtttc aaccaaaaag tctgcctcag ggctactgac tccaatttct tttaaatgta
    57841 aatgcgcttg actgaggatt tgtcccagtc cttcagcatc tttttgtgaa atcgcaactt
    57901 ctgcttgctg ggttaattct cccaaggcat gcaaaaacgg tagggcatcc ttgcccttat
    57961 tttgaaccac ttggatggct tcacgagtat gaccataaac acccgtatcg gcaatcacca
    58021 aataggcgga taaatccatc tcaagttctg taaatcctac gttcttgata aagcgaatag
    58081 gttggtcact gagacaggtc ttagcatcca aaccactagg attcatatgg gcaatcatct
    58141 cagctcgatt gaccaagatt tctagtacat catgaggcag atcagcctga tagtagtcaa
    58201 ataccgcacg aatggccgct atgctgatag ccgctgacga acccatcccc cgtttctcag
    58261 ggatagccga gtcaatctca caacgaatgc aggcttctgt gatatccaaa tactccagtg
    58321 aggcataaac cgccatggac aaggtatcct cctcataaag gcgccaagga ctctctgcag
    58381 gaactacctt acaggtcacc tccacctcca aaagaggcag ggaaatggca ggataaccgt
    58441 aaacgaccgc atgttcccct attaaaatta tcttactatg tgcctgaccg acaccaactt
    58501 tttttgtcat tttttccttt tactagacga aaaaacgtct tatttttcat acaagtatta
    58561 attctttcct atctatttta ttatattttc acaaaaaaag cgattgtttc cattcacaat
    58621 cgcttctttc attattgaac ccattcgcca ttatagttga cagaatagcc atctacggtc
    58681 gtattcactg ccaaggcacc tgagctataa gcgtagtacc atctgccatt gacctggaac
    58741 caacctgtcg tcatagaacg acgaaagaaa ctccataccg ttaagtaaag aggaaagtcg
    58801 tgagggatca tgcgccattg acaacctgtt ttagtgacgt acaaagtctc attaacaagt
    58861 actcgtttcg gccatttata ggtgcggtgt ttggagaaat agggttcaat cttagcccat
    58921 tcttgatcgt ttaaatcagt atcatatgct ttgcgtgtca taactctagt ttaacatttt
    58981 ttgtgaatac aagttctaaa taatcgacca cgaaaatttc ttaagtggaa aacgccttat
    59041 gaagtatgct acgggaaact tatgcactta atttgacaat tcaagatgta aaaatatata
    59101 ctatagtaga ttgaaactag aatagtacac ctctacttct aaaacatttt tagaaatcga
    59161 tttgactgtc ctgatcgatt tgtcctgtta ttattttatt ttactataat atttgacaag
    59221 ttatcctaaa agtattatta tgttgttgtg ttatagattg attgaatcta actaaaggat
    59281 cctattcaat tactagaact atcacatact caaggtcagc tcacagatga gcaactattt
    59341 tggttacaat gtctactaaa tttaagtcaa acaaataatt tagtcaaaat taaaaaaata
    59401 gaggaacata aatatgatta caaaacagaa tgtaatagtg ttctacgatt tttactagat
    59461 aaaactgtaa attctgaagg aaggatcact tcttcaacag aatttggaaa tttcgtaagt
    59521 aatttatcat tccaacacgg aatagctgga ctactgtttc ctctaaataa attgtacccc
    59581 ccagaactgg attctaaaat actctctatc atcaagaagg cagtgacaat tagaacgaca
    59641 cacatatgaa tatcaatact cactgctatt tggtgatgca ggctatctat ggttactcct
    59701 acatttattt tctatcagta aaaatcaata ctatctacaa ttagcaaacg tcaccgctaa
    59761 gaaattaata gagaattatg atactctaga agaaatagac tttgcattgg gaaaatctgg
    59821 tgtcctatta tcattaataa aatactatca atttaccaat gacaatactc ttaaaacttt
    59881 catccacaat agtatatggg gaaatttatc attatttcct acaaagagat acagccaaag
    59941 aaagcatttt agactatagc tttgctcatg gatattgtga aattgcatat gctttatttg
    60001 cctattctaa agtcttagaa ccttctatgt tctataatga tctccataca ttccatgctg
    60061 aattaaaaaa attattagaa aaagttactt ctaatactga aaatttagga aatttacaac
    60121 tttcttggtg cgaaggaatt tccggaataa tcttatatct ttgtatgtac gattgtgacg
    60181 gaaacaaaga tattattagt aaatatcaag aatttgtttt taaccatcat ctaaaaatga
    60241 tgacaggata ttgccacgga ataactagct tactacaaac cactgtctac aatcaaaaca
    60301 aattactgat gaaaaaaatc caacaggtaa ttttagcatg ttctgaacga gatgatcacg
    60361 gtttactgat gtttcaagga gatagtggta aagcagattt gtttgacttc ggaataggaa
    60421 gcagggggta tattggtgtc tattaaataa taaattccca ttcgatgtgc aaacataagg
    60481 agaaatgtat gaaattattt tggacaaaca acatatatag acagttgctg ctaaacagct
    60541 gtttttcatc attcggcgac agtattttct acctcgccat tatcaattat gtggctcagt
    60601 acaatttcgc tccgctagcg attttactga tttccatttc agagatggtt cccctactat
    60661 cgcaactctt tctcgggatt ctaggagatt ttcaagaaaa tagagtcaaa cacgcactct
    60721 gtattgccaa aatcaaaatc ctgctctacg ctattttgac agtatttctc gtcttgtcgc
    60781 ccttttcatt agtttcagtc attatgattg tcatcatcaa cctcatctct gacaccttga
    60841 gctacctgtc tgcctacatg atgaacgccc tctacatcag tgtaattaag gatgacctgc
    60901 atgatgccat ggggttcagg cagtctctga tgagggttgt ccacattgtc gccaatctgg
    60961 ctggcgcatt ccttatcaat gttataagta ttcaaactat ttcccttatc aacactctga
    61021 cttttgtcat tgcctttttg ggcctgtatg ttattcgaca taccttgtat gaggttgaaa
    61081 aaaggattga aatgtcacat acagcactga gttttaagaa atattttcaa catcttaaac
    61141 agtcgctggc tgtgctcctg aggttaaaag ataccgtcat actactgttt ctgacgacca
    61201 gtatgattgc catcttggat gtgtcccctc ggctgattgc cctccgcttc atccaacaga
    61261 cactagcaca actgagcatt gggcaactct tcgccctgct ctccatcatc atgtcttgtg
    61321 gagctatcct tggcaatatg accagcagta atctatttaa aaatatccgt ttcacgcacc
    61381 tcttggtttt ctgtgagatt tccctattgg ctctaataac tagtatcctt tgtcaagcct
    61441 atatcgtaat tttcgtgacc agtttcatca gttctacgat tatcggcatt ctcagccctc
    61501 gcctacaagc agctgtcttt gcccatatcc ccagtgacaa gatggggacg gtgggctctg
    61561 ctctgagcac agtagacatt ctcgccccgt ccctgctctc cctattagcc ctatccatag
    61621 catcgggcgt ttcggtgcag ttagcattga tatttttgta tcttattttg attgctctta
    61681 tcttttgtca atggttagtc aagttcaaca ctcataacta acgaaaaagc atgtgtagat
    61741 ttcacatgct tttaatctcc ccaatcgtca ggtcaagtac aacaaagtca cttctttgat
    61801 taagcgagtg ttctaatata attataagcg ccctgtcatt accgaaccca ttcgccatta
    61861 tagttgacag aatagccatc tacggtcgta ttcactgcca aagcacctga gctataagca
    61921 tagtaccagt tgccattgac ctggaaccaa cctgtcttca tgtctccatt acctgcattt
    61981 aggtagtacc aagttgaacc atcttgatac caaccagttg ccatagctcc tgatgaacgg
    62041 agatagtacc atttgttccc aaggttttgc caacctgttt tcatatcgcc atttggctgg
    62101 tctaaataat accaagtggt accttcctga taccagccag tggccattgc tcctgaggaa
    62161 cggaggtagt accatggagc aggtttgctt ctatcaatgt caatagtaac atgaaaatct
    62221 tgagtccaac ccttagcaac ttcaccaatt ggtagtggat tgtaagaatc atcaccaaaa
    62281 tttcctagct tatttaaata ataccaattg ccgtcttcat aaatccagcc tgtctttaca
    62341 gcataattat tatcaaaata ataagttctc ttttcagcag atagaggata ttgttcaccg
    62401 tatacttttc ctgtattttc agacgttttt gcctctagta cttgtttatc tgtttgttct
    62461 agcaaagcac catcttgtcc aaaatagtac cacttctcct gaaggccaat ttcgaagact
    62521 ggacgattat caaataaatc atcacgataa cctgttccag gaatttctaa gtattgccaa
    62581 ccgacaacca tctctccaat atcaccaaaa tagtaagttt taccgtctat tttatgccaa
    62641 tagattgctt tatgatcatc ttttacataa tattttctat tatccttatc aacaaatcgg
    62701 ccacctgtgg tattcgcaaa taccgtattt gtagctagca aaccaaagaa aaagactgct
    62761 agtagaactt gcatcatttt tttcaaaagt ttcatttata tatcctccta aaacgattgt
    62821 agcaaagaca cgactgcatg tcaatatata aaaactcctc aaaaaagcag ttacacaact
    62881 gcaactgctt ttctattctt gcatggtgta accaacacca cgcacggttt taatgtagct
    62941 tttttgtcct ttaacatcaa gcttgctccg tagatagcgg atatagacat ctacgatatt
    63001 tgtctcggtc gcactttcat acttccaaac actttccaac aattgctcac gagtcaatac
    63061 tttcttgctt cccataagtg tcgccaaaag gtcatactca cggcgggtca gagcaatcat
    63121 ctcttcacca cgataaaccg tgtgatgttc aacatctatc ctaagattgc ggtaggtcct
    63181 tggaactttc atcagactgc agtgttgatc aatgaagtcc cgacctcgga agatcgccga
    63241 aatacgcgct accagatttt cgataaagac tggcttatag atgtatgaaa ctgcaaaacg
    63301 ctgaacaact tccagctctt cttgcaagtc ttcccaatga tctaaaatca tgatgactga
    63361 ggcaggttta gttcgactca atttttctgc aaaatcctga gccatcatat ctcccagatt
    63421 aacgttcaat aaaatcaaat catagtctgt ctgaagagcc atggaaaggg ctttttgccc
    63481 ctcctctacc agatcaaccc gatactgctc tttctggagt tccaaactta aaaaatgagc
    63541 tagatttcgt tctttctcaa gtaataaaat ccgtttcccc atggctgacc tacttatttt
    63601 tcgtcatacc aagagtagtg gaaggttcct tctttgtctt tacgttggta agtgtgagca
    63661 ccaaagtagt cacgttgtgc ttggatcaag ttagccggaa ggtcagctga acggtagcta
    63721 tcaaagtaag taatagctgc tgagaaagtt ggcactggca caccagcttg aaccgcaaga
    63781 gctacgatat cacgcactgc ttgttgatac ttagcagtaa catccaagaa gtactcgtcc
    63841 aaaagaaggt tggcaagatc tgcatcgcgg ttgtaagcat ctgtaatctt ttgcaagaaa
    63901 cgagaacgga tgatacagcc atcacgccag atagatgcga tatctgcaaa tggcaagttc
    63961 cagttgtttt ctttagaggc tacacgcaat tgagcaaatc cttgtgcgta tgaaatgatt
    64021 tttgagaagt aaagggcttg acggattttt tcaatcaatt cagccttgtc tccttcaaag
    64081 ttgaaggcag ctggttttgg aagcaccttg ctagcatgta cacgttcttc tttgtaagtt
    64141 gaaatgtagc gtgcaaacac tgactcagta atcagtgaca atggtacacc aaggtcaaga
    64201 gatgattggc tcgtccattt accagttccc ttgttacctg cagcatcaag gatgtagtct
    64261 acgattggtc catcttggtc ttcatcgtct ttacggctca agatatcagc tgtgatttcg
    64321 atcaagtagc tatccaattc acccttgttc cactcagtaa agatttcagc catatcctct
    64381 gcagaaaggc ctagcaagtg ttgcatcaag tcatagcttt ctgcgatcaa ttgcatatca
    64441 ccgtactcga taccgttgtg aaccattttc acatagtgac cagctccatc aggaccgata
    64501 taagtcacac atggtttgcc atcttctggt gctttagctg agatttcttc aagaacatcc
    64561 gaaaccaatt cgtaggcctc tttttgtcca ccaggcatga tagaaggacc ttcaagggca
    64621 cctttttcac caccagaaac tccagtaccg ataaagttga tacctgagtt tgccaattct
    64681 tcattacgac ggatggtatc tttgtagaaa gtgtttcctc cgtcaatcaa gatatcacct
    64741 ttgtcaaggt gtggaagaag ggcttggata gtagcatctg taccaggtcc agcttgaacc
    64801 atcagcatga tacgacgagg tttttcgatt gagtttacaa aactttcaac gtcatagctt
    64861 ggtacaaaat tcttttcagg atggcaagca atcacatctt ccgttttttc tttactacgg
    64921 ttgtagatag caactgtgta accacgtgat tcaatattaa gggcaaggtt acgacccatt
    64981 acggccatac ctacgacacc aaagttagct tttgtcattt gacactcctc ttgtttcatt
    65041 tgttttattt tatcattttt acttttgaaa agaaagaatt ttgtaacgac tgcttagtag
    65101 tccaagtcat ccgcatgacc agcgccattt ccgacaaagt agcctgtctt acagttaagg
    65161 gtaaagagat aggttccatc tggcttatag aggttgtaat aaccattgcc gttaacgata
    65221 ttgacacgtt caaggatata ttggtctcca gtgatatagc cacgtgaacg tgaagttgct
    65281 agaatttgtt ccaaaacacc atccgcaaaa tcccaggcag agttattact atcatcaata
    65341 gcagactgat tataggcaac acgactggca cttctttgaa cagcaacccc tgcactcgag
    65401 agacccatat tgacttcact gcgactactt ctagtctcat ttgaactact tggttttggc
    65461 tcactagtcg tatttgaact tgcttgactt gaacttgagc tgctagtttg acttgaactt
    65521 gagctagaag tacttgtttg ctggctctta ccaagactga tagccttatc tagcacttta
    65581 tcaagctccg tatttccagt tttaatatcc gtaaatttag catccgattt ggctttggca
    65641 ttggtatcca acacaccatc cacaatagct ggtttttcaa attgtgcatt gacatcttga
    65701 atggccttga tttgcgttac tagactatca tatttagatt tggcaagcgt atgttcacga
    65761 ctaccttcca gcttatcaag taaagtcttg agttgactca gtttatcaaa ctggctattt
    65821 ttcaaagccg ttttattgct atttgtgtaa aaggcgtcat aaagtgtatt aaaatcatcc
    65881 acatccgatt gattggctgt agttgattga gaagtttcaa tttccttggt cgaacgagcc
    65941 acttgacgat agacataata agcactgaca caaataatta ctgatacaag cgccaaaacg
    66001 gtcaaaataa agcctttttt acttttcttt tctgagtcct cttgatccag acgagaaagg
    66061 ttttgctcct cttccacttc ttcagtcatt tctgttggat tttcatcatc tagcaataga
    66121 ggatccaagc cttgctcctc atcgtccaga ggcaagggta gtaagatgtc ttcagaagat
    66181 ggaacttcct ccgaagaagc ttctgacttc tctacagcct cacgcatctc ttgaattaaa
    66241 tcatccagac tctgagtttc aacgaactcc tcttttttgt attgacgagt cgcaaactta
    66301 tccgcctcaa tttcatctct gtgttgctta acatacttgt ccaaaatgga atcctcaggc
    66361 aagactcctg cttccacttc ttcattttta cgaatagctt gaccaactgt tagctctttt
    66421 gcttcatcaa aatcaaattg cggttcttga ccttcttttt tatgacgatt tcgtcttttt
    66481 ttactcatga gtatcccttt ctattttacc tcttgccgtt tgacacgctg accaaaatat
    66541 tgatatagat ccactttcaa ggttccgttg tataacttac gcttcttatc tgcttggcta
    66601 ccatacttgc tttcaaaagc ttcatcacta gtcaggataa atttgctcca agttttcagc
    66661 ggtgcaaata cttgccccat ctcagcatag agcttggtca ctcctgcatc atctgacaaa
    66721 cgttcaccat aaggcggatt ggaaatgatt actccattga ttttatcgga acgtaaatcc
    66781 tgcacgcgca tctgcttaaa agtaatatct cctgcaacac cagctgcctg agcattggcc
    66841 ttagcaattt ccaccatgcg agcatcaata tcacagccca tgatatccaa ctcaagctta
    66901 cgttctactt ttttagccgc ttctgtgcgc acttcttgaa tcaagcgatc gctgatccag
    66961 ttccattcct caaatgcaaa agagcgacga agacctggcg ccatctttct agcaatcata
    67021 actgcctcaa tacagaaagt ccccgaacca caggtcggat caatcaaagg cttgtctgga
    67081 taccagttag aaagttgtaa aatggctgct gccatatttt ccttgatagg agcgccacct
    67141 ttttcggtac gataaccacg tttaaagagg ctagacccgg tcgtatcaat catgacagtt
    67201 gccacatctt tgagaataga gacctcaatc ttaaactctg ggccattctc catcagagga
    67261 accccttctg ggcgagcata gtgtttctgc aatttcttga caacagcttt cttagaaata
    67321 gcctgaacac tgggctcatt gtgaagtttg gacttaacac atttagcttt tgaaatcggt
    67381 aaccgagctc caagtggtaa ataattttcc caatctaaag cgaaaactcc ctgaaatagc
    67441 tcttcaaaag tcttagctgg gaacgttcct acgataattt tgatacgatc tgctgcccga
    67501 agccaaaggt tggtttcgat aatagctctc acgtctcctt gaaaacgaac acgtccattt
    67561 tcaacctgac aatcgtagcc caactctcgc acttcacgac caacgacagc ctcaagccct
    67621 gctgccacag ttgcaattaa attaaattct tttttcatgt tacagtcttg caagaccttt
    67681 ctatatgtcc actttaaaaa atgaggttga gaaaatttct cagccccaac ctatatgcaa
    67741 ttttctataa gccatgtttt gttccagaag tgactaggac cacttccttc gataatcatc
    67801 tgtctaccac taacagctct agctgatagc agtcagaata ctacgttcgt ttccgcatac
    67861 tccatgcccc gaccaaaatt tgggttgcta gcttgagggg tttaccgcgt tccactctct
    67921 ctgtttccag aaagactccg tcactgtggc actttcaagc ctactctggc ctatccaagg
    67981 acttagccat ttcaactgcc gtaacgattt ctcgtcccta ggcttatggt ttcgcctagc
    68041 acaaacacta caggcatcac agcctgtgct agcatggact ttcctcatga gaagcaattc
    68101 tcctcacgcg attatccaaa aattgcacat ctcaaataac tacttaaaaa tctgagttat
    68161 ctaaaatttg tttaccaaaa acttcttttt ccaatctatt caggcgtttc aaaatatcaa
    68221 aattcgtcat agaacttgta attgccgctt caaggggttc tgcttgaact ggtgaaggtt
    68281 tcggtttacg agttaattct tccttcaaat ccgcaatttc ctgacgaagt gacttgacca
    68341 aggcagcata ggtttcatag tccttgatga catcgtctaa aaactcgtca acttctactt
    68401 tattatagcc acggacttca cgtccaaact cttgttcaaa aatatctttc gctgaaaaaa
    68461 taatacttgc catgtctctc tccattctcg cttgctagta ttattatata aaaaaaggca
    68521 aacaaaaatc aaggtcaaag cttcaatttt cggaaaaatt ttcagcaagt tcatttaatt
    68581 gatcaaatgt taatctcttt ataaaatagt cctcttgatt tttcatcttt tggtaaaaat
    68641 aagctagttt tgtttcattt tcttcatcat aaaaaagata ggaactagtc gtgttttcca
    68701 gcaaaaactg ctggtaatct cttaactgcc ccttgtgttc atagcgagga taagcatatt
    68761 tgacaaagtc tacctgctta aagcgactca gtttcatctg attgccttca ttccaatttt
    68821 ccccatgggt ttcaaaagca aaaatggtgg ccaactggaa accgtattcg gttttcatct
    68881 cctgagcaac ctctaaaacc caatattcaa aacccaaact ccctgtaaac acaagccaag
    68941 acaccccatc tgctgccata gcctctaaat ctttacgtat cgctttttta atcaatttaa
    69001 gacgaggatc cttatcagaa aataaaccca aatcaaaagc agaatagcct aaaaccaaag
    69061 ctgtagccat ttttaaccct ttctgtgcaa attatggtat aataaagtga tgttattgta
    69121 ccaataagga gaattatgat caactatcca cataaagttt catcacaaaa aagacaaaca
    69181 tctctttctc aacccaaaaa tttcgcaaat cgaggaatgt cttttgaaaa gatgatcaat
    69241 gctaccaacg actactattt gtctcagggc ttggctgtta tacataagaa accaactcct
    69301 attcaaatcg tacaagtgga ctatccacaa cgaagtcgtg ccaagattgt tgaagcctat
    69361 tttcgacaag cttcaacgac ggactattct ggcgtttata atggatatta catcgacttt
    69421 gaagtcaagg aaacaaaaca aaaacgtgcg attccgatga aaaattttca tccacatcag
    69481 attcagcata tggaacaagt ccttgcccaa caaggaatct gctttgtcct tcttcacttt
    69541 tcttctcagc aagaaaccta cttattgccg gcattcgatt tgattcgctt ctatcatcaa
    69601 gataagggac aaaaatcaat gccacttgaa tatattcgag aatatggata tgaaatcaag
    69661 gctggtgcct tccctcaaat tccttatctc aatgttatca aagaacattt attaggtggt
    69721 aaaacaagat gaacaaacca acgattctgc gcctaatcaa gtatctgagc attagcttct
    69781 taagcttggt tatcgcagcc attgtcttag gcggaggagt ttttttctac tacgttagca
    69841 aggctcctag cctatccgag agtaaactag ttgcaacaac ttctagtaaa atctacgaca
    69901 ataaaaatca actcattgct gacttgggtt ctgaacgccg cgtcaatgcc caagctaatg
    69961 atattcccac agatttggtt aaagcaatcg tttctatcga agaccatcgc ttcttcgacc
    70021 acagggggat tgataccatc cgtatcctgg gagctttctt gcgcaatctg caaagcaatt
    70081 ccctccaagg tggatcaact ctcactcaac agttgattaa gttgacttac ttttcaactt
    70141 cgacttccga ccagactatt tctcgtaagg ctcaggaagc ttggttagcg attcagttag
    70201 aacaaaaagc aaccaagcaa gaaatcttga cctactatat aaataaggtc tacatgtcta
    70261 atgggaacta tggaatgcag acagcagctc aaaactacta tggtaaagac ctcaataatt
    70321 taagtttacc tcagttagcc ttgctggctg gaatgcctca ggcaccaaac caatatgacc
    70381 cctattcaca tccagaagca gcccaagacc gccgaaactt ggtcttatct gaaatgaaaa
    70441 atcaaggcta catctctgct gaacagtatg agaaagcagt caatacacca attactgatg
    70501 gactacaaag tctcaaatca gcaagtaatt accctgctta catggataat tacctcaagg
    70561 aagtcatcaa tcaagttgaa gaagaaacag gctataacct gctcacaact gggatggatg
    70621 tctacacaaa tgtagaccaa gaagctcaaa aacatctgtg ggatatttac aatacagacg
    70681 aatacgttgc ctatccagac gatgaattgc aagtcgcttc taccattgtt gatgtttcta
    70741 acggtaaagt cattgcccag ctaggagcac gccatcagtc aagtaatgtt tccttcggaa
    70801 ttaaccaagc agtagaaaca aaccgcgact ggggatcaac tatgaaaccg atcacagact
    70861 atgctcctgc cttggagtac ggtatctacg attcaactgc tactatcgtt cacgatgagc
    70921 cctataacta ccctgggaca aatacccctg tttataactg ggataggggc tactttggca
    70981 acatcacctt gcaatacgcc ctgcaacaat cgcgaaacgt cccagccgtg gaaactctaa
    71041 acaaggtcgg actcaaccgc gccaagactt tcctaaatgg tctcggaatc gactacccaa
    71101 gtattcacta ctcaaatgcc atttcaagta acacaaccga atcagacaaa aaatatggag
    71161 caagtagtga aaagatggct gctgcttacg ctgcctttgc aaatggtgga acttactata
    71221 aaccaatgta tatccataaa gtcgtcttta gtgatgggag tgaaaaagag ttctctaatg
    71281 tcggaactcg tgccatgaag gaaacgacag cctatatgat gaccgacatg atgaaaacag
    71341 tcttgactta tggaactgga cgaaatgcct atcttgcttg gctccctcag gctggtaaaa
    71401 caggaacctc taactataca gacgaggaaa ttgaaaacca catcaagacc tctcaatttg
    71461 tagcacctga tgaactattt gctggctata cgcgtaaata ttcaatggct gtatggacag
    71521 gctattctaa ccgtctgaca ccacttgtag gcaatggcct tacggtcgct gccaaagttt
    71581 accgctctat gatgacctac ctgtctgaag gaagcaatcc agaggattgg aatataccag
    71641 aggggctcta cagaaatgga gaattcgtat ttaaaaatgg tgctcgttct acgtggagct
    71701 cacctgctcc acaacaaccc ccatcaactg aaagttcaag ctcatcatca gatagttcaa
    71761 cttcacagtc tagctcaacc actccaagca caaataatag tacgactacc aatcctaaca
    71821 ataatacgca acaatcaaat acaacccctg atcaacaaaa tcagaatcct caaccagcac
    71881 aaccataaca tttatcaccc agatttttct gggtgatttt gtcatagcac tattgtattt
    71941 atgtgcttaa caaaagcctg agaagatgtc ttctcaggct ttttctgtac tataaacctc
    72001 attggaaaag atagagactg cttccgtaat cttgttaaga ggttttacta aatactagtc
    72061 tttcttcgtt tttactacaa agagagcaga tagggctaga ctaacacttg ctaggaagag
    72121 ggctgtgtca gattgactct cacctgttgc tggcaagatt tgttcaggtg tttctggtct
    72181 agctatttct tgcttataat ctggcgtctt accttgatcg gaaactaaag agctaagttt
    72241 aaactcaggt ttctctacag ttggagcatc tggtttcgta gcagaatctt ttaattggtt
    72301 gagataatct gcaaagtatt ccaccattct ttccgtcaag agatggttat ccgtcgcata
    72361 tttcatgctt gcctgaacgc tagctacttc ctcttgattg tctttgtctg ttaatttctg
    72421 agctttagcc aaagctgctt catagcctga caagtcaaga ggtgtttctg ctacctgtgg
    72481 acgagtaaag atgagttccg ctgcagattg gtatttatcg ccaccatctc cgtaagtctt
    72541 agtacctgta aggacaattt tcttagcctt aattgtctta ccaaaatcaa tgtcttttgg
    72601 cttattgtta tctggccaat cagttgcagt aaaggtatgc tccttgccag actcatctgt
    72661 cacaacaagt ttcacatcac gcaagttacc atttgaacct gatccacgtg gaacgtaacg
    72721 aagtccagtg atttcagttg gttctttcaa gaccatggtt gcaggcttgc ctacatctcc
    72781 accattccaa gatgtatgcc ataaactaga taagtttcca tcaaaggcat ttgcaagacc
    72841 ttcttgagcc tgagcaggag ctgtaagact tgcaaagtca tctgctacca aagccgtttt
    72901 cttctgaacc aaagcattct tcaaggcttc aatcttggca atctctgcac gcgcttcttc
    72961 cacactgata tcatcatcgg cctgactaag gttaaagacc gcctctttca aagcatccat
    73021 agactctttg gtgtagttag tcatggcaac cgttggcaag tagttcttca gagcattttc
    73081 tgtcaacatc ttacctgtta gggtaatttc ttcgatttga agattatcca tcatgaagtc
    73141 gttataacca cggaagttgg catttccacc agaatcacca cgagtattac ttgcattgcc
    73201 agttgagtag atacctaccc aagtatcccc tgtttctgca cctgtcacaa ggaaggttgc
    73261 cttcttggct ttcttagaat ctgtccaagt atttggcaat tcatgcattt ccaagttgct
    73321 tgcttgagtg ccacgacgac ctgactggaa ttctccctta ccgactacaa aagcataggt
    73381 attgtctgaa cctgcttcgt attcaaaggt tacacggtag gtcttacctg cttcaaaacg
    73441 gaagttttgt gggatggttt ggtaaaccaa gttacgacgg ctcactagtc catttgtctt
    73501 gagtgaccaa tttccttcga taacatcatc gactttctta ccgttccaac cacgttgtgt
    73561 atatggatcg tgtttttcag acaagtgagt gcggttgtct tcgacacctt cgacaccacc
    73621 cactacaaat gggaagattc cttgagctac attttcaaag tcttgcttga aggttccttg
    73681 acctgtatcg tgcttgtctc catacatgct tgaattgttt tcaaaggtac gaatttcatc
    73741 aaagtaagtt gcttgatcac cagcttcacg actcaatgtc agagtaacat ttgagacgtc
    73801 cgatcctgtt gtaaagaagg cgtacatgtt ttggaagtaa cttgtatcgt taactgtagc
    73861 attgttacga cgtgtattgt gggcgtaggc ttttacatag ttgagggcga gagacttatt
    73921 ggtataagta gtcacttctt tttcaccagt attcacagtg atacttgcct tggcattact
    73981 acggttatcg acaccgacat aaacggcata cttggtattt ggtttcaagc cagttaattt
    74041 ctgagtgaga ctaacttttt ctttgtttcc ttgaatacga agcatatcgt ttgccccttg
    74101 agacttgaca atttctgcct tagaagcatc gcctgaaatg gtccaatgtt tcaaggtacc
    74161 actgttaaat ccttggtcat agatgtgcat gccttcactc catgacattt caggattggt
    74221 ttgttttgaa cgatagagaa cgtatggttg atttgctaga agatctaggg taattttacc
    74281 atcttttaca gttagttctt gctcttctgt cttaccttgg tcagttagct tgtaaaggta
    74341 aaccttgctc tttgcccaat cgcttggaag ggtccaagtt gttgcaccgg cctgcgtatt
    74401 gaagtagtac atcttttcct tatcagtaga aagtttctta ccatttgcat cccagttcca
    74461 aggagtcaag taagctgaac catcttggat gacacgtccg ttgagagtta ctgtacgttc
    74521 gcgatattgt ggactattga catcatttga cttacgagtt acaactactt tattattgtc
    74581 agcatctacc aattccactc gcatttctgg agtccattta taggtactac cgttatcggt
    74641 catagtcacc ggtgtaccat tttcccattt acttacagtg aagtgttgga agtacttagt
    74701 catgacgtca tgggcaaata agttggttac atagccattg tagtcacttc ttccctgcca
    74761 gccttcaaag tctttcatgc tgtagccacc tagcagtgga tagttggctg caccaccata
    74821 acttctgtag tccccaaccc aagcatcttt ttggtggtta cggataaagc gggtgatggc
    74881 actgttgata cctttattgg tgtagccacc gtaggtcaag tcagctgccc agtgatggaa
    74941 ggtagagtcg tactcaccac catggcccca ctcgatcgca aagcgccagc cttgtttgtt
    75001 aatttcttta gcaagaacgt gggtagccca ggcaccgtta tcacctgatt gaccattacc
    75061 ccaaacgtcc acatagataa agtcgagacc gtcaccaagt tttttcttca aatcttccca
    75121 acgtgccaaa cgaccatgag ctaggtcata ggcagcatca atgttgatac cttgatctag
    75181 ccagttccaa ccatagctat agcttccatc tggattctta cggagaattt tttcattgaa
    75241 gtatttagac tcaggataag tttctgaagc gttaacgtgg atacctagat gagctccata
    75301 tttcttagcc ttctcaatta gggtcttgaa gtcttcgaca ccaccgatac gcttaccaat
    75361 atcagcatag ttcaagtgac cagagtcatg gccttcgcta ccatatcctt taaggaaaac
    75421 accttgccca agaccatctg tgtggagatt gattttcttg ataccatcca aggtcataag
    75481 gaatggattt tgtgcttgag aaccaaagtt catcgcgata cggtaagctg tgatatcctt
    75541 aactttttcc caaccttgag gattgttcat aatgctacga taagcaatgg caccatcttg
    75601 ccaatcgact ttcttgtctg cattggcatc ttcagtgata acaaccttag cacttggaag
    75661 ttccttcgtg tattctggga aaacaatgcc cttataagct ttttcccatt gccattcaga
    75721 gctgtggatt cctacatagt tggcatttcc gactgtttct ttataagctg tcaaacgagt
    75781 ccagtcattc gaaccaccac catagctatt ttgagagtta ctccaaacac cagcagcaag
    75841 cttatctgta gaaacaaatc catacatgta acccttggct aggtctttca ttggattggt
    75901 tacatcgata tgatcatctc cgctgacatg cgtattgttt gacatggttg ccccatcaaa
    75961 cttagcacca gtttgatcac tagaaacaga gactaaagca ttgccgagga aactaataga
    76021 agaaagtagt tttctttcgt catcaatctt ttgacctgga gtgacttgat tgtggttgac
    76081 aatcttggtc acatcaaagt gcaattgatt gtccacaact tgcaagcgta ctgtcatttc
    76141 cgcattgatt aagtgagcat catcgcgaag cttcatcaag tactctgctg ttgtctcatt
    76201 gattttctta taagtgactt caggggtgat tcggtggtta ttgataaaga cttggttgaa
    76261 ctgttgcacc tgtcctggca aagtatgtcc attcaagctg tattccttga cacgagggaa
    76321 ggcttggtca atcactgctt tgaggacctt agactggatc gtatcataag tcaccttgct
    76381 atcgtcaaca accggacctg tttctttctg ggcaggagta tcatccgctt ttacgccttc
    76441 ttgattgtct gttttaacgc tgacaactgt acggtcattg ccataagttc ctgccttgag
    76501 aaggatcttc ttctcatttt taagattatc attgaccgcc ccaggcagtg tcactgtgtc
    76561 aaagagattg acatcgttat tgctggcatt gagttgtcca tctgacttga gagtgataga
    76621 aagacggttt acagaacccg gttctggtgc aactacacgg ttgcctttat accatgtgct
    76681 attacctgga gttttgtatt cccagaacca gccatccttg tcataaccga caaaaacatt
    76741 attattggta tctttaaatt tcaggaagac accaaagcgt gatttgccct tttcagaatc
    76801 ttctttgaag gttaaatcaa cagttgcatt tccattggca tcaacggtca agcccttctt
    76861 ttcaaacagg gctggtttgc ctgcgttatc attttgagca gttgagaata gttggttgta
    76921 gcggacacct ttttcttctc ggatagtgac tgttccctgt tgttcttttt tctctaccgt
    76981 ttgccattca ggagttaccg tcttaggtgt ttcaggttta gcagctgcag gtttatcctc
    77041 ttttggtttt tcttcagccg gtttttcttt ttcaagtgct aatagttctt cttctgtctt
    77101 aggtccatct gtaacttctg gagaaccttg gtcttctccc accttaggcg cttcaaaatc
    77161 acgcccatca ttctcgtttg ctgttgcaag agcagtagct aaatcagctg gtaagttcgc
    77221 cgtggaacca gactgcacgc tatctgcaag aaccggactt gtcccaaaga atgcagctcc
    77281 aatcataaca gaagcaacac ctaatgaaaa tttccgaata ctatatttac aacgtttttc
    77341 aaataatcct ttattcataa acttctaaat cctttcattt tttagcaagc gtttacattt
    77401 cctttttaaa aaatactcct tcctctgaaa gtgcaatgct taaccctgat aaataaaaaa
    77461 taattgtact tttaatataa caaataatag ctgagaaagc aataggaaac aagtaaaatt
    77521 aacaaaaatt ttctctattc tgacaaaaag aggctccaac ttttgggggt cagtacattt
    77581 agaatctttc tttacaaatg taaaaaagga ttcagcattc aagagaaata ctaaatcctt
    77641 tcttatattt tgcaacagtt atttcacatg ttttgcgaga tcttcttgag cctttttatt
    77701 agactcttct ttttctttca tccatttttc ctgagctttt tggtattcat ctacagtgac
    77761 tgccttgtct tgaagttcca agtatttata caagactggt tcacttgtac ctttatttcc
    77821 tgacaatgca aatggtattg taaatggtac catcttagac aagattgggc gccctgtacg
    77881 agatgtagtt ggaataatca aagcactatc tgtcaaccaa gcttgggctg cagcgtattt
    77941 atcatagcgt ttagcaacat ctgtagcctc atcaccagcc tcagtgacca atttttcgta
    78001 gtcatataga cctacttttt tagcagctac attatcttcc cctgagtcaa accctaaata
    78061 tgttttagta ctttctccta cagaaggttt gataatatca aggtaggttg atggatcggc
    78121 aaagtctgga ccccaaccga cattatctga taaatcccag tcttcgccag cagcattttc
    78181 agcaaaatat gtaatattgt ttacttcgtc tttttgtagt tgttggatat caataatgac
    78241 attatcagct cctaaagttg cttccaagga ttgtttcata gattggacgc gctgaacttt
    78301 tgtagttgct gtctggtcaa ctggcatatc caaatgaatt gggaaagtca caccttctgc
    78361 ttgtaaggct gatttagctt tagcaaattc agccttggct ttttctggat tgtaaagacc
    78421 atcctgagaa tctgcaagat taacatcctt ccattcatcc ccataagtga ccaatttctc
    78481 tttgaccata tcgccaaagt ttttaccatc tgcttgaaca aatgttggtg gaacaaagat
    78541 attacgtaag attttgcttg ctccagtttg tccattcaac tgagaggcat aggctgtacg
    78601 atcaaaacca aaggcaatag cctgacggaa atccttgttt aagagagcct ttttagtcga
    78661 tgccttttgt tcgtcgctgg tcttagatgt atatttatag gactgacggt caatatttgt
    78721 accaactaga tacgtaatag agccttgttg agtatagaca atattgtcct tcatactctt
    78781 ctcaagctct gcgaaacttg cacttgttgg atagagacga gctgctgtaa ggctaccatc
    78841 tttaaagttt tctgcaggtt tgctggtatc ttgaccatcc cagaatgaca atttaacttt
    78901 gtcaacatgc acattgtcct tatcccagta gttcggattt ttcgcaaatt caacagagga
    78961 ttttgtcaca atggatttca acaaataagg accgttatac aagagactac ttggatccgt
    79021 cgctttggca aaatcatccc cttttgagtt caaaaactct tcattaactg gcgcaagcac
    79081 acccatggtt gtcttagaat tccagaagct ttctggtttg ttcaaagtgt actgaactgt
    79141 ctgatcatcc aaagccttaa ttcctacttg tgagaaatct ttgatttccc cttttacata
    79201 ggcatccaac cctttgattg attcttgaac aaggtaaaga gcatctgatt ttttatcagc
    79261 agcatatttt agtcctgtta caaagtcttg agctttgact gccgcgtatt cttcaccttc
    79321 agaagtatac cattttgcat ccttacggat agtataagtg taagtcaatc catccttgga
    79381 tacagaccaa tcctcagcca tagacggcac aaagttcccg tagcgatcat tttctagcaa
    79441 accatcaacc acgttactgg taatatttgc tgtcgcagcc ttagcagttg tcaaatagtt
    79501 gaggttatca gggtctgtct cataaatgta tgagaatgtc ttctcacctt tagtgcttga
    79561 acctgatcca gagcatgcag ctaaagtagt cgccgccaat aatgtcacgc ccgcaagggc
    79621 aagtagtttt gaacttttca tccttttctc ctttaaaact ttctctccat tatagactct
    79681 tttcagaaag ttgtcaacag aattttcaga atttttgaaa attatttttc aaataacatc
    79741 tttgcaaaaa atatgaatat cgtaaccgcc caataacgaa gtctattgaa aaatctccag
    79801 actagagaac tcacggatag ttcctaatct ggagatttct tatttgcact tttcttgtac
    79861 aactttagtc cacggtaaat aggcctctaa aatctctttg tttacgagag tttcctcgtt
    79921 tggaagacat tctagaagat aggatagata tttctcgcta tttaattata atagctcttg
    79981 ctttagctcc ttcaaaactt tgagaaaata accaccctcg cttttttaaa ctgagcttag
    80041 gctaaaagag tccactggac tcttttactc cgtcccataa ccaatgattt aatggcgcat
    80101 tcagctagat tattggaaag gaccagatgt ccgtctttca aaatagtctt aaaggtttct
    80161 tcatacttga ggctgtattc aattgccctt cctagttttg aacctgctaa aactgactga
    80221 cgccggcacc aagcaaagaa gtcttccatt aggggctgga gatgttcttg acgtttctgt
    80281 agtcgttcat cagctggcaa agcctcccag tctctttcca gggaaaataa ctgatcacaa
    80341 taagctaaac ctttagctcc taaggatgat ttatccgttt gcttgggggg cgcttcaaaa
    80401 aacttccttc tcacatgtgc ccaacatcca acaagttcag cttcttccag ttgacgataa
    80461 gcttctagcg gttcgcagtt taccaagctt agcgtcgcct tgctcctaaa ccttggactg
    80521 ctatcgcata ggcagaacta gaggactaaa gtcctaagtt actgccgcaa catatcacaa
    80581 tgcacatagc cagaataatc tcctaggaat tcttgtacta ctaaaccact ccgacgctga
    80641 tcatggtggt acagcgtgat tgcttgattc tcagctttcc cagacaaaaa agtccaatag
    80701 taggtcagat ggctatcact ctctagaacc cgataagagg tttcatccgc atgaagaaga
    80761 ggttgttcta acaacttttc tcgtaaaagc ttataaaggg actctaaata gtattgactt
    80821 gccttgatat gccaattaga gatttcctta cgtgtgattg gtaaacccat cctagcccaa
    80881 tcttcttctt ggcgataatt gggtaccttc agattaaact tctgatggat ggtgtgagcg
    80941 ataatagaaa ctgagccaaa gctatgcacc aaagagacca gcaccaacaa caagataatt
    81001 gtacatctta agctcctttg gagttcatta tctgcctctt ttattagact agaaaatcat
    81061 tctactactt atctcacttc ttgtttgtaa aattcttgca atgcatcttg ccaagttgga
    81121 ataacaaatc cagtagcttt ggctttggcc aggctcatcg ttgagtttag cggacgttga
    81181 gctttggctg gaaattgact ggaatctact ggcttgactt cgacatctgt atctttcaaa
    81241 atttcaactg caaaatcata ccatgttgtg tcttctgtcg catcatttga caaatgataa
    81301 taaccaaatt ccttacgatt ttcagctagg tagatcatga attcagccaa ggtacgagtc
    81361 caagtcggac gaccgtactg gtcatttaca actgttaaag tcttatgagt tttcgcaaga
    81421 ttttgcatgg taaaaacgaa gtttttgcca taatttccaa atacccaggc agtacggata
    81481 atatagaaat tagacacatg cttctcaact aactcttccc ccatacgctt agtgcgtcca
    81541 tattctgtct gtggatctgg tcggtcatca acttcccact cttgtccaac tggtttctta
    81601 ccgtcaaaga cctagtccgt agaaatataa actagagttg caccatgctt ttcagatgct
    81661 tttgcgacat tttttgtccc catcacattg atggcgaagt ccaactcttt tccttcatcc
    81721 tctgctgcat caacagcggt gtaggctgca caatggtaga ctaaagtcgg tttcacctct
    81781 tcaaaaactt tctcaaccat ttcttcattg gtaatgtcca tctcagccac atctactgcc
    81841 acgtattctt cattacgttc atccaataaa tagcgaagtt ccgttcctaa ttggccattt
    81901 gcccctgtaa ttaaaatcat ctctagacct ttctaatatg taactcttcc caatatagca
    81961 ataaaaagca gcgatttcct gctttttata ctgtaataat ctcctgagtc ttagcataat
    82021 tggcttcaac agcttctttt tctgctttcc accattcttg gttatctgta taccacttga
    82081 ttgttgcctt gagcccagct tcaaagttgg taaattcagg tttccacccc aactcatcac
    82141 ggagcttgct ggcatcaatc gcatagcgaa ggtcatgtcc tgcacggtca gtcacatgat
    82201 cataggcatc cgtagcttgt cccatttcct taaggataag ttccaaaact tccttattgt
    82261 tcttctcacc atcagcccca atcaagtagg tttcaccgat ttgccctttt gtcaagattg
    82321 tccaaactcc tgaagaatgg tcattggtat gaatccagtc acgaacgttc ttaccttcac
    82381 cgtaaagttt tggcttaatt ccacttagga tgttagtaat ctgacgtggg atgaattttt
    82441 cgatatgttg ataaggaccg tagttatttg aacagttgga aatcgttgcc ttgactccaa
    82501 aagaacgcac ccaggctttg acaatcaagt ctgatgcggc cttggttgat gagtacggag
    82561 agcttgggtt gtattttgtt tcagcagtaa atttctcacc tggtccttca ccatgacctg
    82621 gcaaatcttc tcgtaaaggg agatccccat aaacttcatc tgtcgataca tggtggaagc
    82681 gaatatcata cttacgagca gcttctaaaa gagtatagat tccaatgaag ttagtatgaa
    82741 taaatggcga tggatcattg agcgaattat cattgtggct ttccgctgca taatgaacga
    82801 tagcatctgc ttgagcaacc aacttgtcta ccaactccgc atcagcaatg tcaccaacaa
    82861 ctaactcaac acgattgcct aaaatttcct caatattcgc gcggtttcca gcataagtca
    82921 acttatctag gactgtcacg tgaacatctg gaaagttctc gtaaacataa tggacaaagt
    82981 tagaaccgat aaagccagct ccacctgtca cgataatatt tttgtattca gtcatattct
    83041 ttccttattc caaatcttct tttttcaaag gcttcacgtc cttaagtagg ggatgatgtt
    83101 tgtctgcttc agatacgtct gcttcttcca gattttccca ttcaatacca aggcttggat
    83161 cagcgtagtt cacaaaggca tacttgggtt tgagttcaag agcccagtaa tcattgacca
    83221 gatagctata tgacactgta tctgataaaa cttggaagcc attagctacg cctcgaggaa
    83281 caaagattcc cttgcttgca tcaattactg tctgataggt attcccaaag gtttcaccct
    83341 cgcgtagatc aacccaagaa cccagaactt tccctccatc tgctacagag atgtacttat
    83401 cccaaggctc tgcgtggagg cctcgaagga catttttacg tgagaaggat acattgtttt
    83461 gcaattttcc ttctgcaaag aaagactctg gaaatccaag tggaagcact ttttcctttt
    83521 ggaaattttc tttaaaccag ccacgattat ctccatgaac ggggatatca aactccaaca
    83581 tgcctggaat agcttcaacc ttgcgtgccg caagcgtctt accgaaaaaa ttatctgtca
    83641 tctatgcttc tccaatcaaa cggagcagat actgtccgta ttcatttttc ttaagtggtt
    83701 gggctaaggc caatacatct tctcgactga tatagcccat acggtaagca atttcttcta
    83761 agtttgctac ctgaacattt tgcatccgtt gcactgtttc gatgtactgt gaagcctcta
    83821 gtaaactttc atgagttcca gtattcagcc aagcaaagcc acgtcccata agctcaacag
    83881 acaaatcacc acgatctagg taagccttgt ttacatctgt aatttccagt tcaccacgag
    83941 ggcttggttt aatactcttg gcaatttcga caacatcgtt atcatagaaa tacagtcctg
    84001 tcactgcata gttggagcga ggatactccg gtttttcttc tatggaaata gcattcatgt
    84061 ctgtatcaaa ctcaaccaca ccaaaacgct ctggatcctt cacttggtag ccaaaaacag
    84121 tcgcaccttt ctctttcttg gctgcttttt gaagcattgt gctcagacca ggaccatggt
    84181 agatattgtc gcctaaaatc aaggcaacgc tatcgtcaga aataaactct tccccaattg
    84241 ccaaaccatc tgtacttggt tgctctgcat aagaaagttt gatcccaaac tcagatccgt
    84301 cttgaagaag ctcttgaaat cgatgtaaat cctgtggagt ggaaataatc aaaatatccc
    84361 taatcccagc caacatcaat gttgaaagtg ggtagtaaat catcggttta tcataaaccg
    84421 gcataagttg ttttgacgca gcgcgagtca aaggatataa acgtgtcccc gaaccacctg
    84481 ctagaataat acctttcata gtagggtacc tttctttgtt attttagagt caattactat
    84541 taattgtgta ctgctctaaa aagaaaacaa tcatcccatg ttttatatgg ctctataata
    84601 tttgtagtgg gtaaatccac tatagatatt atggagccta ttttattgta gaaaaaaagt
    84661 cccataagat ctataatgaa aagcgaccaa acaactcatt agaaagattc atatgggaca
    84721 attacatttt atcac
//
LOCUS       DAVBEM010000003        83338 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVBEM010000003 DAVBEM010000000
VERSION     DAVBEM010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 83338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83338
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.003"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            <1..165
                     /locus_tag="VQ548_000188"
     CDS             <1..165
                     /locus_tag="VQ548_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2653117.1"
                     /translation="AYNHALSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLI
                     AGIINHELGF"
     gene            233..481
                     /locus_tag="VQ548_000189"
     CDS             233..481
                     /locus_tag="VQ548_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653118.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRIYSGNLILQELITVNGAYKATYIGELSSN"
     gene            612..1784
                     /locus_tag="VQ548_000190"
     CDS             612..1784
                     /locus_tag="VQ548_000190"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HET2653119.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENADSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            1784..3058
                     /locus_tag="VQ548_000191"
     CDS             1784..3058
                     /locus_tag="VQ548_000191"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HET2653120.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLEFANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLIGILSNYATDSL
                     VTASCRMAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VAFSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(3094..4059)
                     /locus_tag="VQ548_000192"
     CDS             complement(3094..4059)
                     /locus_tag="VQ548_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2653121.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQTIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(4040..5494)
                     /locus_tag="VQ548_000193"
     CDS             complement(4040..5494)
                     /locus_tag="VQ548_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET2653122.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKSQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            5871..7754
                     /locus_tag="VQ548_000194"
     CDS             5871..7754
                     /locus_tag="VQ548_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2653123.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYALADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVSKGDAVIE
                     VKI"
     gene            7903..8790
                     /locus_tag="VQ548_000195"
     CDS             7903..8790
                     /locus_tag="VQ548_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2653124.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGTSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(9110..9727)
                     /locus_tag="VQ548_000196"
     CDS             complement(9110..9727)
                     /locus_tag="VQ548_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HET2653125.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(10142..10330)
                     /locus_tag="VQ548_000197"
                     /pseudo
     CDS             complement(10142..10330)
                     /locus_tag="VQ548_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(10840..10920)
                     /locus_tag="VQ548_000198"
                     /pseudo
     CDS             complement(10840..10920)
                     /locus_tag="VQ548_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            11036..11929
                     /locus_tag="VQ548_000199"
     CDS             11036..11929
                     /locus_tag="VQ548_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2653126.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            11926..13125
                     /locus_tag="VQ548_000200"
     CDS             11926..13125
                     /locus_tag="VQ548_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2653127.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLEQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(13478..14245)
                     /locus_tag="VQ548_000201"
     CDS             complement(13478..14245)
                     /locus_tag="VQ548_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653128.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(14262..14957)
                     /locus_tag="VQ548_000202"
     CDS             complement(14262..14957)
                     /locus_tag="VQ548_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2653129.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(14962..15327)
                     /locus_tag="VQ548_000203"
     CDS             complement(14962..15327)
                     /locus_tag="VQ548_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2653130.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMIH
                     FGYEKEELPGVVSDYIKGV"
     gene            15467..15940
                     /gene="nrdR"
                     /locus_tag="VQ548_000204"
     CDS             15467..15940
                     /gene="nrdR"
                     /locus_tag="VQ548_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HET2653131.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            15941..17110
                     /locus_tag="VQ548_000205"
     CDS             15941..17110
                     /locus_tag="VQ548_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HET2653132.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFNPKEATIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKTKTQKQNQTAPAKTNIPKWSNPDYKNETSEETRLELERKKQELLARLEKGGD"
     gene            17111..18007
                     /gene="dnaI"
                     /locus_tag="VQ548_000206"
     CDS             17111..18007
                     /gene="dnaI"
                     /locus_tag="VQ548_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HET2653133.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            18004..18717
                     /locus_tag="VQ548_000207"
     CDS             18004..18717
                     /locus_tag="VQ548_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HET2653134.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            18731..20041
                     /gene="der"
                     /locus_tag="VQ548_000208"
     CDS             18731..20041
                     /gene="der"
                     /locus_tag="VQ548_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HET2653135.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            20132..20467
                     /locus_tag="VQ548_000209"
     CDS             20132..20467
                     /locus_tag="VQ548_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653136.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            20607..20942
                     /locus_tag="VQ548_000210"
     CDS             20607..20942
                     /locus_tag="VQ548_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653137.1"
                     /translation="MEYLFKMIILLPCFYFFSWIEKANRDSKIFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            21127..21918
                     /locus_tag="VQ548_000211"
     CDS             21127..21918
                     /locus_tag="VQ548_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653138.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLEWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYVVPYMVLKKYEDNV"
     gene            21911..22552
                     /locus_tag="VQ548_000212"
     CDS             21911..22552
                     /locus_tag="VQ548_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653139.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLIVSRLEEKFKKG"
     gene            22556..23206
                     /locus_tag="VQ548_000213"
     CDS             22556..23206
                     /locus_tag="VQ548_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2653140.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            23217..23504
                     /locus_tag="VQ548_000214"
     CDS             23217..23504
                     /locus_tag="VQ548_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653141.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     MQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            23650..26163
                     /gene="secA"
                     /locus_tag="VQ548_000215"
     CDS             23650..26163
                     /gene="secA"
                     /locus_tag="VQ548_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HET2653142.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMATLTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQAMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            26244..27275
                     /locus_tag="VQ548_000216"
     CDS             26244..27275
                     /locus_tag="VQ548_000216"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET2653143.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            27277..28308
                     /locus_tag="VQ548_000217"
     CDS             27277..28308
                     /locus_tag="VQ548_000217"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET2653144.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            28347..28715
                     /locus_tag="VQ548_000218"
     CDS             28347..28715
                     /locus_tag="VQ548_000218"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HET2653145.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            28705..29808
                     /locus_tag="VQ548_000219"
     CDS             28705..29808
                     /locus_tag="VQ548_000219"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HET2653146.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLALPYDLIPALTLESALVHIKTVPAGACMGYGATYQTDSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            29827..31842
                     /gene="recG"
                     /locus_tag="VQ548_000220"
     CDS             29827..31842
                     /gene="recG"
                     /locus_tag="VQ548_000220"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HET2653147.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     IKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            32158..33138
                     /locus_tag="VQ548_000221"
     CDS             32158..33138
                     /locus_tag="VQ548_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HET2653148.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            33943..34170
                     /locus_tag="VQ548_000222"
     CDS             33943..34170
                     /locus_tag="VQ548_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653149.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            34458..37355
                     /gene="nanA"
                     /locus_tag="VQ548_000223"
     CDS             34458..37355
                     /gene="nanA"
                     /locus_tag="VQ548_000223"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HET2653150.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGNRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPNRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            38370..38822
                     /locus_tag="VQ548_000224"
     CDS             38370..38822
                     /locus_tag="VQ548_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2653151.1"
                     /translation="MIITKISHLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVQLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            38841..40178
                     /locus_tag="VQ548_000225"
     CDS             38841..40178
                     /locus_tag="VQ548_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET2653152.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            40257..41141
                     /locus_tag="VQ548_000226"
     CDS             40257..41141
                     /locus_tag="VQ548_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2653153.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            41141..41974
                     /locus_tag="VQ548_000227"
     CDS             41141..41974
                     /locus_tag="VQ548_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2653154.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            41992..44085
                     /gene="nanB"
                     /locus_tag="VQ548_000228"
     CDS             41992..44085
                     /gene="nanB"
                     /locus_tag="VQ548_000228"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HET2653155.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKRSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNREESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            44097..45200
                     /locus_tag="VQ548_000229"
     CDS             44097..45200
                     /locus_tag="VQ548_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2653156.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            45374..46072
                     /locus_tag="VQ548_000230"
     CDS             45374..46072
                     /locus_tag="VQ548_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2653157.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            46091..47608
                     /locus_tag="VQ548_000231"
     CDS             46091..47608
                     /locus_tag="VQ548_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2653158.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFLGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            47733..49061
                     /locus_tag="VQ548_000232"
     CDS             47733..49061
                     /locus_tag="VQ548_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2653159.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            49313..50179
                     /locus_tag="VQ548_000233"
     CDS             49313..50179
                     /locus_tag="VQ548_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2653160.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            50195..51034
                     /locus_tag="VQ548_000234"
     CDS             50195..51034
                     /locus_tag="VQ548_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2653161.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            51307..51759
                     /locus_tag="VQ548_000235"
     CDS             51307..51759
                     /locus_tag="VQ548_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2653162.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEATDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPTGYAGMEEKVRKYLFKILID"
     gene            51856..52200
                     /locus_tag="VQ548_000236"
     CDS             51856..52200
                     /locus_tag="VQ548_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653163.1"
                     /translation="MVSSKHAARASFLDGQEITVDEMSWIINGIVNALIGRYIKLGTY
                     AAKYGIGIARSILSRAAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            52484..53128
                     /locus_tag="VQ548_000237"
     CDS             52484..53128
                     /locus_tag="VQ548_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET2653164.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            53297..54214
                     /locus_tag="VQ548_000238"
     CDS             53297..54214
                     /locus_tag="VQ548_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET2653165.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTATHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKESFL"
     gene            54232..55116
                     /locus_tag="VQ548_000239"
     CDS             54232..55116
                     /locus_tag="VQ548_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2653166.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(55132..55983)
                     /locus_tag="VQ548_000240"
     CDS             complement(55132..55983)
                     /locus_tag="VQ548_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2653167.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANRVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            56183..58240
                     /gene="pbp2b"
                     /locus_tag="VQ548_000241"
     CDS             56183..58240
                     /gene="pbp2b"
                     /locus_tag="VQ548_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HET2653168.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTKRQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEINKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            58251..58847
                     /gene="recR"
                     /locus_tag="VQ548_000242"
     CDS             58251..58847
                     /gene="recR"
                     /locus_tag="VQ548_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HET2653169.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            59023..60066
                     /locus_tag="VQ548_000243"
     CDS             59023..60066
                     /locus_tag="VQ548_000243"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HET2653170.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            60150..61523
                     /locus_tag="VQ548_000244"
     CDS             60150..61523
                     /locus_tag="VQ548_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HET2653171.1"
                     /translation="MKLTIHEVAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGVRDGHDFIERAFENGAAATLSEKEVANHPYILVDDVLTAFQQLAAYYLEKTAVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQVLDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGVQSVQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            61510..62121
                     /locus_tag="VQ548_000245"
     CDS             61510..62121
                     /locus_tag="VQ548_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2653172.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRDLLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDPLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            62212..62916
                     /locus_tag="VQ548_000246"
     CDS             62212..62916
                     /locus_tag="VQ548_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HET2653173.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            63135..64508
                     /gene="ftsA"
                     /locus_tag="VQ548_000247"
     CDS             63135..64508
                     /gene="ftsA"
                     /locus_tag="VQ548_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HET2653174.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENIIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVESVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            64525..65784
                     /gene="ftsZ"
                     /locus_tag="VQ548_000248"
     CDS             64525..65784
                     /gene="ftsZ"
                     /locus_tag="VQ548_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HET2653175.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            65789..66460
                     /locus_tag="VQ548_000249"
     CDS             65789..66460
                     /locus_tag="VQ548_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HET2653176.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            66470..67009
                     /locus_tag="VQ548_000250"
     CDS             66470..67009
                     /locus_tag="VQ548_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HET2653177.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            67009..67272
                     /locus_tag="VQ548_000251"
     CDS             67009..67272
                     /locus_tag="VQ548_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HET2653178.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            67269..67953
                     /locus_tag="VQ548_000252"
                     /pseudo
     CDS             67269..67953
                     /locus_tag="VQ548_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
     gene            67962..68750
                     /gene="divIVA"
                     /locus_tag="VQ548_000253"
     CDS             67962..68750
                     /gene="divIVA"
                     /locus_tag="VQ548_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HET2653179.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            69098..71890
                     /locus_tag="VQ548_000254"
     CDS             69098..71890
                     /locus_tag="VQ548_000254"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HET2653180.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYANFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEEPAPEAALSFEDVVFTVERAAGEVCDRCRRIDPTTAERSYHAVICDHCASI
                     VEENFADAVAEGFEEK"
     gene            72300..72662
                     /locus_tag="VQ548_000255"
     CDS             72300..72662
                     /locus_tag="VQ548_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653181.1"
                     /translation="MKSSGIVGLVGGILLLICPFVLLGTAVNTAATTLNGGATAGAFS
                     GVALLLNALKIANLVLGIIAIVYYKGDKHVGAAPSVLMIVSGEVSLIPFLGWVGGILA
                     IIGGSLFLATLKKFKSEE"
     gene            73197..73889
                     /locus_tag="VQ548_000256"
     CDS             73197..73889
                     /locus_tag="VQ548_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HET2653182.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            73942..76353
                     /locus_tag="VQ548_000257"
     CDS             73942..76353
                     /locus_tag="VQ548_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET2653183.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     RKAFASFPDDLLIQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYSGNLFSY
                     KGQEYIEAARAILNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            76603..77304
                     /locus_tag="VQ548_000258"
     CDS             76603..77304
                     /locus_tag="VQ548_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2653184.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIQMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            77306..80006
                     /locus_tag="VQ548_000259"
                     /pseudo
     CDS             77306..80006
                     /locus_tag="VQ548_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
     gene            complement(80102..80593)
                     /gene="tpx"
                     /locus_tag="VQ548_000260"
     CDS             complement(80102..80593)
                     /gene="tpx"
                     /locus_tag="VQ548_000260"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HET2653185.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(80716..81645)
                     /gene="psaA"
                     /locus_tag="VQ548_000261"
     CDS             complement(80716..81645)
                     /gene="psaA"
                     /locus_tag="VQ548_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HET2653186.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(81677..82525)
                     /locus_tag="VQ548_000262"
     CDS             complement(81677..82525)
                     /locus_tag="VQ548_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET2653187.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(82522..83244)
                     /locus_tag="VQ548_000263"
     CDS             complement(82522..83244)
                     /locus_tag="VQ548_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET2653188.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT        25200 a        15193 c        18400 g        24545 t
ORIGIN      
        1 gcctataacc atgcgctatc taaggagaga agcaaggttg agaacatctt tgccaaagta
       61 aaaacgttta aaatgttttc aacaacctat cgaaatcatc gtaaacgctt cggattacga
      121 atgaatttga ttgctggcat tatcaatcat gaactaggat tctagttttg caggaagtct
      181 actactttcc ttattgtctg taaatctact gaccttgttg tttatcccag tcatggtttc
      241 tagttcgggc tcagagtttc aaagtggatg gcaagagcat caattgattg ctgagaaggt
      301 tagtaaaaca cttgataaga catttgataa ggatgtcaga gaaattccga ccagtcagtt
      361 ttatcaaaaa tttgtagatg agatgggaag gatttactca ggaaatttga tcctccagga
      421 gctgataact gtgaatggag cttataaagc tacttatatc ggtgaactct ctagcaacta
      481 atcattcttt aaaatgatga ccaataagag gcttgatttg gtgaatcaag tcttttttct
      541 ctcttttact gccatttgtg ataaaatagt atagaacgat tttttacatg aatgataaaa
      601 cagaggtaaa tatgacaatc ggtattgata agattggttt tgcgaccagt caatatgtct
      661 tgaaattaca agacttagca gaagcgaggg gaattgaccc tgaaaaatta agtaaaggac
      721 tcttactcaa ggaattgagt attgcgcccc taactgagga catcgtgacc ttggcggcca
      781 gtgctagtga ctctatttta actgagcaag aaagacaaga agttgacatg gtcattgtgg
      841 ctaccgagtc aggaattgac cagagtaagg ctgcggccgt ctttgtgcat ggcttgctgg
      901 gcatccagcc ctttgctcgt agtttcgaga ttaaagaagc ctgctatggg gcgacagctg
      961 ccctccatta tgccaaattg catgtggaaa attctccgga gtccaaggtc ttggtcattg
     1021 ccagtgatat tgccaaatat ggtattgaaa ctccgggaga accaactcaa ggtgctggaa
     1081 gtgtagctat gttgattaca caaaatccac gcatgatggc ctttaataat gacaatgtag
     1141 ctcagacccg tgacatcatg gatttctggc gaccaaatta ctcgacaact ccttatgtaa
     1201 atggtgtcta ttctacccaa caatacttgg atagtttgaa aacgacttgg cttgaatatc
     1261 aaaaacgcta ccagcttact ctggatgatt ttgcggctgt ttgtttccac ttgccttatc
     1321 ctaaattagc gctaaaaggc ttgaaaaaaa tcatggataa gagcctgcct caagagaaaa
     1381 aagacctctt acaaaagcat tttgaccagt ctattctcta cagtcaaaag gtggggaata
     1441 tctacacagg ttcacttttc cttggacttt tgtctctctt ggaaaatgca gatagcttga
     1501 aagctgggga taaaatcgcc ctttatagtt acggaagtgg agctgtggct gagttcttca
     1561 gtggtgaatt ggttgaagga tatgaagctt atttggataa agaccgcttg aacaagctca
     1621 accaacgaac tgccttatcc gttgcagact atgaaaaggt cttttttgag gaagtaaact
     1681 tggatgaaac aaactctgcc cagtttgctg gctatgaaaa tcaagatttt gccttggttg
     1741 aaattctcga ccaccaacgc cgttatagca aggttgaaaa ataatgaaga taagttggaa
     1801 tggattttct aaaaaatcat accaagagcg cctcgagctg ttaaaagctc aggcgctcct
     1861 tagtcctgag agacaagcta gtctggagaa ggatgaacag atgagtgtga ctgtggcaga
     1921 ccagctgagt gagaatgtag tgggaacttt ttctctgcct tattcgctgg ttccggaggt
     1981 acttgtcaac ggtcaggaat acaccgttcc ctatgtgaca gaagaaccct ctgtggttgc
     2041 ggcggccagc tatgccagca aaatcatcaa gcgtgcaggt ggttttactg cacaagtcca
     2101 tcagcgccag atgattgggc aggtagccct ttatcaagtt gctaatccta aactagcgca
     2161 agagaagatt gccagcaaga aagcggagct cttggagttt gccaatcaag cctatccttc
     2221 tatcgttaaa cgtggaggtg gggcgcgtga tctgcatgtc gagcagataa aaggcgaacc
     2281 agactttctc gttgtttata ttcatgtcga tacccaggaa gccatgggtg ccaatatgct
     2341 caacaccatg ctggaagcct tgaaaccagt cttagaagaa ctcagtcagg gacagagtct
     2401 cataggaatc ctgtccaact acgcgaccga ttctctggtg actgcaagct gtcgcatggc
     2461 ctttcgctac ttgagccgcc aaaaggatca aggacgagag attgcggaga aaattgcgtt
     2521 ggctagtcag tttgcgcagg ctgatcctta ccgagctgct actcataata aaggaatttt
     2581 taatggtatt gatgcgattt tgattgccac tggtaatgac tggcgtgcca tcgaagctgg
     2641 ggcccatgcc tttgccagtc gagatggacg ctatcaaggt cttagttgct ggacgctgga
     2701 ccttgaaaga gaagaattgg tcggtgagat gaccctgccc atgcctgtag cgactaaggg
     2761 tggctctatc ggcctcaacc cacgtgtagc tttcagtcat gatctactag gaaatccttc
     2821 tgccagagaa ttagcccaga ttatcgtgtc catcggtctt gcccaaaatt ttgcagccct
     2881 caaagctttg gtaagtacgg gcatccagca aggccacatg aaactacagg ccaaatccct
     2941 agctctccta gctggggcta gtgaatctga agttgctccc ctagtagagc gcctcatctc
     3001 agataaaacc tttaacctag agacagccca gcgctatctc gaaaatttaa gatcataaaa
     3061 aactcagacg aatcggtctg agttttcttg tgtttaaata ctttttcctg gtaatagtgt
     3121 aactggtaag aagtaaccag ttgtggcaac ttccttgcct tcaatctttt gcaagagaag
     3181 atcaatagtg agacaagcaa tctcttccaa aggttgcttg atagtagcca attgagggta
     3241 gtaattttcg ataaagtagg tcccatcata gccgatgacc ttgagctctt ttgggacaga
     3301 aatgcccaat tcttgagcga ttttaatgac cagaatagct gtcaaatcat ccgaagcaaa
     3361 aatggcatct ggtttttccc gggtcaagat attcttgatt tccatttctt ttctgacggg
     3421 agaaaagtca ctggaaacat tgataatagg agcttttggg agtacggatg caaaaccagc
     3481 gtggcgtagt ccggttggcg aattggaatt gtcattccct gtaatcatga tgatagtctg
     3541 ggcacctgtc ttgaccaagg tttgggcagc aagaacccca ccagcatagt tgtcagagga
     3601 gacgacaggg atgtctggcg ataggtttcg gtcaaaggaa ataatcggcg ctgtcacacg
     3661 attgtagtct tcgattccta ggttgtgact accagaaatg atgccgtcca cctgattggc
     3721 ttccaacatt tcgatgtatt cgcgttcctt ctcagaatca tgttcactgt tgcagatgat
     3781 ggtcttgtaa ccatttttga agagttggtg ttccaattta tcaatcaatt ctgcatagaa
     3841 aacattggaa atattaggga aaatcaagcc gattaactta gctgattttc cttgcagact
     3901 acgagccagg ttgttgggtt tatagcccaa ttctcgcatg gcttcattga ctttttggat
     3961 ggttttctca gatagatacc cttttttatt gataacccga gaaacggtag taggactgac
     4021 gcctgcaagt ttggcgacat cagttagttt tgcgaccata atctaattca tagtaagttc
     4081 cagttgggtt tccagatttg atcaggatac cattttggtc cgcatgtggg aagacacgac
     4141 cagaaaatac tttttctcct ttattgatga aaatttcaaa gacagagtta tcgatgaaga
     4201 ttgtagcagt agtagcctga ttctcgatag ggcaagaacg agttgtccca aattcttggg
     4261 catactgttc tccagcctgg ctacgatcca ctgtcacttg accgtttaca aggtcaaagt
     4321 tgattgaaag tcccttacct tctttatcag caagtaagac aatctcgctc tggctattag
     4381 cttccaagtt gagttcaagt tcgtaagtgt tcttggtttg ggaacggttt gagaaggctt
     4441 cttcagaagc acgaaggtcc ttaatagcag cgactggata ctggtagagc ttgtcgtctt
     4501 tgatagtgag ttccttgacc aaagagaagg ttccttggtg gtcaaaacgg tcagatgggt
     4561 aagaaacatc tggcaaacca agccagctaa ctgctagagc acgcccatca ggagcgttga
     4621 aggcttgagt tgcataggct tcgaaaccgt aatccatgtt ttgaagttga gacacatcta
     4681 ccattttggc atttttaggg tcaaaggaag ccccaatctt atacatattt ggaaagatat
     4741 tatcgtagtc tagaactttc ttatccaatc cttgtggaca gtagagaagg acaggatgtt
     4801 cctctacaaa gaccagatta ggacattcca tcatgtaggc agtacggtcg ttagcaaagt
     4861 caaggtcgcc aactgcttgc cagtttgtgt agtcgttatt gacagccttg tagagacgga
     4921 cgaagccttt tttctccaag tcctgtccac cgacgacagc atagtattga cttttaaagt
     4981 taaaaatttg tggatcgcgg aagtggtcag tagagtctgc tggctggtca atcaagatct
     5041 tgtcaatctt tgtaatctta ccctccttgt ccatcaaagc accgatctgg tatgggtgac
     5101 ggatccagtt ttcatcgcga acatttcctg tataaaatag gaataagtta tcgccaaatt
     5161 gcatggcaga accagagtag gcaccgtggc tatctaatgg agtatctggt aaaactttga
     5221 ttccagtttc tttaaagtga accaaatcat cactttctag ctgtgcccaa gatttcaaac
     5281 cgtgggctgc accaaaagga aaattctggt aaaagaggat ccacttgcca tcaaagtaag
     5341 aaaagccatt tgggtcgttg agaagtcctg tttttggctc aacatggtaa tgagtatgcc
     5401 atggagattg tgccatattt tcctttatat gttgaatttc ttcttgcgtc caatcttgat
     5461 aaagtctgta acgacgctca gttgtccatt ccattcattc ctccaaaaat cttatcactt
     5521 ttaatagtaa ctgttttcga taaaaaatgc aagcctttta tgttaaaaaa gaggaaaaac
     5581 tgtcaaacga ttatcataaa ataaatacag gaaatcaatc aaatttttac gaaaatgtga
     5641 aagataatga aataaaagac tttttaacca aggtttcaaa cttatttttc aaggaattcc
     5701 tgatgaaaca gtcaaaaaca atcaatctaa aacttgccca ctaagtggat agaatatttt
     5761 ttctgcaaaa cgcttgacat atttttaaaa catgataaaa taatagtcgt aagggcgaat
     5821 aaaatcgctt tcaaacaaga acaaaatgtt atataaggag atttttgcaa atgaacaatc
     5881 aggaaattgc aaaaaaagtc atcgatgcct tgggcggacg tgaaaatgtc aatagtgttg
     5941 cccactgtgc gactcgtcta cgtgtcatgg tcaaagatga agagaaaatc aataaagaag
     6001 tgattgagaa cttggaaaaa gttcaaggtg ctttctttaa ctcagggcaa taccaaatta
     6061 tctttggtac aggtacagtt aacaaaatgt acgatgaagt tgttgtactt ggcttaccaa
     6121 catcatctaa ggatgacatg aaagcagaag ttgctaaaca agggaactgg ttccaacgtg
     6181 ctatccgtac tttcggtgat gttttcgttc caatcatccc agttatcgta gcgacaggtc
     6241 tcttcatggg tgtgcgtggt cttttcaacg ctcttgaaat gccacttcca ggtgactttg
     6301 caacttacac acaaatcttg acagatacag ccttcatcat cttgccaggt ttggttgtgt
     6361 ggtcaacctt ccgtgtattt ggtggaaatc ctgccgttgg tatcgttctt ggtatgatgc
     6421 ttgtctctgg ctcacttcca aacgcttggg cagttgctca aggtggtgaa gtaacagcga
     6481 tgaacttctt tggtttcatc cctgttgttg gtttgcaagg ttccgttctt ccagccttca
     6541 tcatcggggt tgtcggagct aaatttgaaa aagctgtccg caaggttgtt ccagatgtca
     6601 ttgacctctt ggtaacacca ttcgtgacac ttttggtcat gtctatcctt ggactctttg
     6661 tcattggacc agttttccac gttgttgaaa actacatcct tattgctaca aaagcgattc
     6721 ttagcatgcc atttggtctt ggtggtttct tgattggtgg ggttcaccaa ttgatcgtcg
     6781 tgtcaggtgt gcaccacatc ttcaacttgc ttgaagtgca attacttgct gctgaccatg
     6841 ctaacccatt caacgctatc atcacagctg ctatgacagc tcaaggtgct gctactgttg
     6901 cggttggtgt taaaacaaaa aatccaaaac tgaaaacact tgctttcccg gctgctcttt
     6961 ctgccttcct aggtattaca gagcctgcta tcttcggggt gaacttgcgc ttccgtaaac
     7021 cattcttcct ttcattgatt gctggtgcaa tcggtggtgg attggcttct atccttggac
     7081 ttgctggtac tggtaatggt atcaccatca tccctggtac aatgctttat gttggtaacg
     7141 gacaacttcc acaatacctt cttatggtag ctgtatcatt tgcccttggt tttgctctta
     7201 cttacatgtt tggttacgaa gatgaagtag acgcaactgc agctgcaaaa caagctgaag
     7261 tggctgaaga aaaagaagaa gttgcgccag cagctcttca aaatgaaaca cttgtaactc
     7321 ctatcgtcgg tgatgttgtc gctcttgctg atgtcaatga cccagtcttc tcaagtggag
     7381 ctatgggaca aggtatcgct gtgaaaccaa gtcaaggcgt ggtctatgca ctagctgatg
     7441 ctgaagtttc aattgccttt ccaacagggc acgcttttgg tttgaaaaca agaaatggtg
     7501 ctgaagtttt gattcacgtt ggtattgaca ctgtatctat gaacggtgac ggttttgaag
     7561 caaaagttgc tcaaggtaat aaggtgaaag ctggcgatgt tcttggaaca tttgactcaa
     7621 acaaaatcgc tgcagctgga cttgatgata caacaatggt tatcgttaca aatacagctg
     7681 actacgcttc agtagctcca gtcgcaacag gttcagtttc gaagggggat gctgtgatcg
     7741 aagtgaaaat ctaatcaatc ctctctaatg tgaaaacgaa caaatgacat gtttgttcgt
     7801 ttttattaga tagtaagatt tacagaggaa aatctaaaaa atagagacat ttagactttc
     7861 gaagtatgct ataataaaga aaataaaaac aagaggttta tcatgacaaa attatatgga
     7921 agcttggaag cgggcggtac aaagtttgtc tgtgctgtcg gtgatgaaaa ctttaacgtt
     7981 gtagaaaaaa cacaatttcc aacaacaact ccaatcgaaa caatcgataa aaccattgag
     8041 ttcttctcaa aattcgataa ccttgctggt cttgcagttg gttcatttgg gccgattgat
     8101 attgacaaaa actcaaaaac ttatggcttt atcacgacga ctccaaaacc aaactgggca
     8161 aatgtggact tgcttggtgc ccttcgtcgc gccctaaacg tgccaatgta cttcacaaca
     8221 gacgtaaaca gctctgctta cggtgaaatg gttgctcgta acaatgctgg tggtcgtatc
     8281 gaaaacttgg tttactacac aatcggtaca ggtatcggtg caggcgtcat ccaacgtggt
     8341 gagtttatcg gtggtgtggg tcaccctgaa atgggtcatt attatgttgc tagacaccca
     8401 atggatattg aaaaagagtt taagggtgtt tgtcctttcc ataagggatg tctagaaggt
     8461 tatgcagctg gtacaagttt ggaagctcgt acaggtgtac gtggggaaac tattgaactc
     8521 aacaaccctg tttgggatgt tcaagcctac tatatcgctc aagctgcggt taatgcgaca
     8581 gtgactttcc gcccagacgt gattgtcttt ggtggagggg tcatggctca acaacatatg
     8641 ctggaccgtg tccgtgagaa atttacatct cttcttaatg gttacctacc agtaccagat
     8701 gtgcgtgact atatcgtgac gccagcagtc gcaggaaatg gttctgccac acttgggaac
     8761 tttgttcttg caaaagaagt ttcaaaataa agcacaaaat ccgcttggga aaccaaacgg
     8821 attttgtggt tgaaaacaat atttttgagc ctttccttaa gtgattacgg acggtagcga
     8881 ctttcttcga aattccatac ctaaactttg agcctagtgt ctcaaagttt ccgaatacct
     8941 gaaaccatta gatttcaggt gtttctatca cggcggaaag gctaggtaag tcctcgcctc
     9001 actatcgaaa aatatgcata atttccatac caaagtatat ttagtatcaa gctatagtta
     9061 atctacgctt taaaaatcca cttgggaaac caaacggatt ttttacgtgt caaagcattt
     9121 gccagaaaaa gtcaataata taggtcagac cgtaggtata aaccacgagg gtaaagggtt
     9181 tggtcagaat gatgatagtc atgtagcgct tgaaactcat cttggtcagg gcggccagca
     9241 tacagagaaa gtcagctggg ctaatgggcc aaatcatcat aaaaataaag aagcggtcaa
     9301 aacgattgcc cttatctagc cagccgatgt acttgtcgta ggtgcgcttg ctgacgacag
     9361 actggacaaa ggcagctccg tataggcgca ctagataaaa gataatggca cagccaatca
     9421 cgatgccgat atagttgtag atagtcccga tgatgtgccc gtagataaag accccagcca
     9481 ccgaggtcaa ggcccctgga atgataggga cgacagtctg taaaatctgt aaaaagataa
     9541 agagaggtgg accccagatg cctgcctgct ggataaaggc agagagggtt tccttggatt
     9601 gtaaaatccc agcctgataa gcccaaatac agaaaatcaa actcccaacc ccaccgacaa
     9661 tcgatgagat attgataact cgctgcagaa ggggagaaac agctttcatt tgtttatcct
     9721 gtgacatgta aactcctcat agatagtata tttctactat accatatttt ggaggagaaa
     9781 gggggaatga gtcttttttg ataaggaata gaaagtaaat agcccttcga gacttagaat
     9841 aggtctgtca actaaaggtt atatgcattc taggtttcga ataatcgcaa ttccataaat
     9901 ttaaaagtat tctaagtttc gaatagctta tctgagataa ttttgaggca ttcgcgcttt
     9961 cgaatagtca ttttccctaa agtttatatg tattctgaag ctagaaagac taaaatataa
    10021 aagtagtaag agtctctctc tgatggacgt aatttatggc tagtatgaat cctttgaatt
    10081 gttagttaat tttaatatta atcagttctg aaataattac taaatatagt tagatggtga
    10141 gttaattatt gctaaatttc aagttcaagt tagtcatcca gaagtcttct ctgggggact
    10201 tgtagttcaa gcatttttta ggatagttgt taatccactt ttcgataaat gcgacttcct
    10261 ttgtagttgt tttcttagtt ccctgaggta accatctatg aatgagcctg ttgtgatttt
    10321 cattagatcc tatagtgatg tgcataatag atatagcaga ttgaaactag aatagtatac
    10381 atctacttct aaaacattgt tagaaatcaa tttgactgtc ctgatcaatt tgtcctgttt
    10441 ttatttcatt ttactatata atccttagaa aacatatcgg acaagcggtt gaattccgtt
    10501 ccgtccatta gtagataaag gattactcct tcttgaaatg acagatgaac ttgtttctta
    10561 taaaaatgtt gtctgaaact attagccttt ttccagaagt tttagaggaa gaaaacttta
    10621 cgaggaaaaa ggagttactc aaataacaat tcaggattaa aaatagacag ttgaggagcg
    10681 gaaggtataa attaagtttg ctactgtata atggatttat cactaatact cttcgaaaat
    10741 ctcttcaaac cacgtcagct tcgccttgcc gtagatatag ttactgactt cgtcagttct
    10801 atccacaacc tcaaaacagt gttttgagct gacttcgtca gttttatctg caacctcaaa
    10861 gctgtacttt gagcagccta cggctagctt cctagtttgc tctttgcttt tcattgagta
    10921 taaaagtgct ccaggccata ttttacacag caatagtctt ctaaaaatgg acaaaaacat
    10981 tgtaaaggct atcaaaaagg agtataatga gtgcaagaaa tttcggaggt gaaagatgct
    11041 agaagtaaga agtctagaga aaagttttgg ctccaagcaa gttttgtttg gtattgactt
    11101 tcaagcgcga ccaggtcgta ttttgggact agtcggaaaa aatggtgctg gaaaaacaac
    11161 gattttccat agtattttga aattcctaga atatcaggga gaaatcggtc tggatggtca
    11221 ggatattcgt caggagacct atgctcggat tggttatctg cctgaagaac gcagtctcat
    11281 gcctaaattg acagttcttg aacaagttcg ctacttggcg actctaaaag gcatggatgc
    11341 caaagaagtc aaagaaaaac tccctcaatg gatgaagagg ttggaagtga aaggaaagct
    11401 gacagataaa atcaagagtc tgtcaaaagg aaatcagcag aagattcagc tcattattac
    11461 tctgattcat gaaccagacc tgattatctt ggatgagcct tttagtggat tggacccagt
    11521 taatacagaa ttgctcaaac aagtcatttt tcaggaaaaa gagcgcggag caaccattat
    11581 cttttctgac catgtcatga ccaatgttga ggaactttgt gacgatattc tgatgatccg
    11641 agatggccgt gtggtcttgc acggaccagt tcaggatgtc cgcaatcaat acgggaaaac
    11701 gcgtctcttt gtttcaagtg aacgaagcaa ggaagaattg gaaaatcttc ctcatgtcaa
    11761 acaggtgagc ttgaccaaac aaggcagttg gaaattgatt ttggaggatg agagcgctgg
    11821 aagggaactc ttcccaatct tgactcaagg tcaatatatc gcaacatttg accaacaagc
    11881 gccaactatc gatgaaatct ttaaactaga atcaggagtg gaagtatgag aaatatgtgg
    11941 gttgtaatca aggaaaccta tcttcgacat gtcgagtcat ggagtttctt ctttatggtg
    12001 atttcgccgt tcctcttttt aggaatctct gtaggaattg ggcatctcca aggttcttct
    12061 atggctaaaa ataataaagt ggcagtagtg acaacagtgc catctgtagc agaaggactg
    12121 aagaatgtaa atggtgttaa cttcgactat aaagacgaag caagtgccaa agaagcaatt
    12181 aaagaagaaa aattaaaagg ttatttgacc attgatcaag aagatagtgt tctaaaggca
    12241 gtttatcatg gcgaaacatc gcttgaaaat ggaattaaat ttgaggttac aggtacactc
    12301 aatgaactgc aaaatcagct taatcgttca actgcttcct tgtctcaaga gcaggaaaaa
    12361 cgcttagagc agacaattca attcacagaa aagattgatg aagccaagga aaataaaaag
    12421 tttattcaaa caattgcagc aggtgcctta ggattctttc tttatatgat tctgattacc
    12481 tatgcgggtg taacagctca ggaagttgcc agtgaaaaag gcaccaaaat tatggaagtc
    12541 gttttttcta gcataagggc aagtcactat ttctatgcgc ggatgatggc tctgtttcta
    12601 gtgattttaa cgcatattgg gatctatgtt gtaggtggtc tggctgccgt tttgctcttt
    12661 aaagatttgc cattcttggc tcagtctggt attttggatc acttgggaga tgctatctca
    12721 ctgaatacct tgctctttat tttgatcagt cttttcatgt acgtagtctt ggcagcattc
    12781 ctaggatcta tggtttctcg tcctgaggac tcagggaaag ccttgtcgcc tttgatgatt
    12841 ttgattatgg gtggtttttt tggagtgaca gctctaggtg cagctggtga caatctcctc
    12901 ttgaagattg gttcttatat tccctttatt tcgaccttct ttatgccgtt tcgaacgatt
    12961 aatggctatg cggggggagc agaagcatgg atttcacttg ctattacagt gatttttgcg
    13021 gtggtagcaa caggatttat cggacgcatg tatgctagtc tcgttcttca aacggatgat
    13081 ttagggattt ggaaaacctt taaacgtgcc ttatcttata aatagaagag ccttgcgaaa
    13141 gcgaggtttt taaaggtgaa aagggtggaa tcacgaacct aatgatgtac acattatgta
    13201 aacaggttgc ttgaaaactc aattgtatag tgaactgaat ctggaatagg ataatattac
    13261 ttctaaaaca ttcttataaa ttgatttgaa ttccaaaatc ccatcgttcc gttcttattt
    13321 cattttgcga tatagtgaaa ggaaataagt cagctcacaa aaaacgcata atatcaagga
    13381 tttttaacac ttgatactat gcgttttcta attttaaaga ctttttgcct ggtctctttt
    13441 gttctatgag tatgttacat atctaggtaa aaattattta aagcaaatta accttatttc
    13501 tcaagatgta gtaggttccg agataaaaga tagctatgaa tatgagttct ttaacaatgg
    13561 ctatacctgc tcccatatag aaatggtcat tgagtcctac cagtgaattg acatagaaat
    13621 tagaactaag attgaagaaa agttcaataa atccaatgac gatttggata ccaatgtagg
    13681 ctgcaacagc gagtgctgta cggtattcat tgaaaagctg tccaatggaa atagccaggt
    13741 agatgcagag gattcctgaa atggtattta gtaggaagga tatacctgta agaaagatct
    13801 gagggagatg tgtttctaca aatgtaatca cataagaaag aggaatccat tctggagctg
    13861 ttaaagccag aataataaca gcacttagag ccaatacagc ggtgctaatc aatgaccaga
    13921 taaaggcacc gattagtttg gctgtgatga tatggtgttc agaaactggc aaggtcaaag
    13981 tcagatagcc ttgtcggtcg tagacactac ctttgaagcg tttaataatc aagaaaatgg
    14041 ttgaaatcgc aagtgtaagc atcaagccac caaagactgt agctagaaaa agtagcatag
    14101 tagcctgact ttcttggtaa ggtagatttt taaagccttg tgtctgtatt ccgatgaggg
    14161 cagaaaggac tagcacggct gcgtagaggg ctaaatacca cttgttaaca tttttaaatt
    14221 cgtagtgaac taaattccaa aacataaata atctcctttg cttaggcctt aaattcctga
    14281 cggaagagtt ggtcaatgga ttcacctgac tcgtagcgaa tatcatctac atttccttga
    14341 cggacgactt ttccgtcttt taggaagaca atttcatcca agattggctc gatatcagaa
    14401 atcaagtggg tagaaatcaa aacggtagaa gttggtgagt agttgttgat aatggtattg
    14461 aggatataag cacgggctgc tggatccacc ccaccaatgg gttcatccaa aacatagaga
    14521 cgagcatcac ggctcataac caaaatcagt tgaacctttt ctttgtttcc ttttgatagt
    14581 ttcttgagac gactattttc atcaatgccc aggtctgcaa gtagatgatg agcgcgttca
    14641 agattgaaat ctttatagaa ggtcttgaag taggttaggg cttctttgac cttcatttgc
    14701 tcattgagat aggtcgtatc aggcaaataa gctacaacgg ccttggttgc tgggcttggg
    14761 tccatgtcgt tgatgaggac acgtccttga tctggttgta agaggccatt aattagttta
    14821 atcagggttg tttttcctga gccgtttggc ccaagaaggc cgacaatttt tccagctgga
    14881 atgtcaagag aaacattttc aagggctggt gttgctccat atgatttgga tacattttca
    14941 aatactagta atgacatagg cttaaactcc tttaatataa tcactgacta cgcctggtag
    15001 ttcttctttt tcatagccaa aatggatcat ggaggaaacg aagtgttcca attcttcttc
    15061 tgataattgt ttgcgtgact gagcgattag ctccttatcc ttagtcacaa atcgtccagt
    15121 tgttcgcttg ctgtagacaa atccttctcg ttcaaggtct gataaggctc tttggatggt
    15181 attgggattg acaccagcct cgctagctag ctccctcacg gttggaagtt gttgattggg
    15241 ttccagtgta tgggaaacaa tctgaagctt gattttctcc ataatctgta aatagatggg
    15301 ttttttgttg tcaaatgtcc aggacatctt agtctccttt ctcttatcct tttgtcttaa
    15361 ctaaataata caacaaaaca aaaaacttgt caagcaaaaa gaagaattgt tttgggaatc
    15421 gcttaaaaaa tggtataatg aaaagaaaac gataaggagg gaaaggatgc gttgtccaaa
    15481 atgtggggct accaagtcaa gtgttatcga tagtcgccaa gcagaagaag ggaacaccat
    15541 tcgtagaaga cgtgagtgcg acgaatgcca acaccgtttt acaacctacg aacgagtaga
    15601 agaaagaacc ttagtggttg ttaaaaaaga tggtacacgg gaacaattct ccagagataa
    15661 aatctttaat gggattatcc gctcagccca gaaacgtcct gtgtcaagtg atgaaatcaa
    15721 catggtagtc aatcgtatcg aacagaaact ccgtggtcga aatgaaaatg aaattcaaag
    15781 tgaggacatt ggttcactcg tcatggagga gttggctgaa ttggacgaga ttacctatgt
    15841 acgttttgct agtgtctatc gtagttttaa ggatgtcagt gagttagaga gcttgctcca
    15901 acaaatcacc cagtcctcta aaaagaaaaa ggaaagataa atgaagccaa ttgaccgttt
    15961 ttcttatcta aagaataatc gggtgtcgca agatacctca tctctggtac agtgctacct
    16021 cccgattatc ggtcaggagg cactgagcct ttatctttat acaatcagtt tttgggataa
    16081 tggtagaaag gaatatcttt tttcaagtat cctcaatcat ctcaactttg ggatggatag
    16141 actgataaaa tcattgaaaa tcttatctgc ttttaatctc ttgaccctct atcaaaaggg
    16201 ggatgtttat cagctagccc tccatgctcc tctatctagt caagacttct tggagcatcc
    16261 tgtttatcgc agactcttag agaaaaagat tggcgactct gctgtggagg atttgaaagt
    16321 tgaaagtgct gatggtgaag aaatacctgt ctcactcaat caagtctttc cagaattggc
    16381 agaactaggc agtcaagaag accttggtct caagaagaaa gtggccaatg attttgactt
    16441 ggaacatttt cgccagctga tggctcgaga tggacttcgt tttgcggatg agcagtccga
    16501 tgtcttaaac ctctttgcta ttgccgagga gaagaaatgg acttggtttg aaacctatca
    16561 attggccaag tcaacagctg tttctcaggt tatttcaacc aaacgcatgc gtgaaaaaat
    16621 tgctcaaaaa ccagtttcct ctgactttaa tcctaaggaa gcaaccatta tcaaggaagc
    16681 taaaagtaag actgccctgc agttcttagc agaaatcaag caaacacgca aggggaccat
    16741 tacccaaaca gaaagagaac ttttgcaaca gatggctggc ttgggcttgc tggacgaagt
    16801 catcaatatc attctcttgt tgacctttaa taaggtggat tcggcaaaca tcaatgagaa
    16861 atatgccatg aaggtggcta atgactatgc ctatcaaaag atacattcag cagaagaggc
    16921 cgttttacga attcgtgagc gagggcagaa aacaaaaaca caaaaacaga atcagactgc
    16981 cccagcaaaa accaatattc ctaaatggag taacccagat tataagaatg aaaccagcga
    17041 ggaaactcgt ctggaactag aacgtaagaa acaagaacta ttagctcgat tagaaaaagg
    17101 aggagattag atggaaagtg tcggagacgt actcaaacgt caacccagcc gtttttatta
    17161 tcaagatttg gtccagaaaa tcatgaagga ccctgatgtt gcggctttta tccagcaaga
    17221 atccttgact ccagaggaat taaatcgcag tatctccaag tttaatcagt acatcaccga
    17281 gcgtgacaag tttctccgtg gggatacgga ttatattgcc aaaggctaca agccgatttt
    17341 ggttaagaat catggctatg cagatgtttc atatgaagaa actcctgagc taatcgcggc
    17401 tgaaaaagaa gcggctatta agaatcgtct caagctaatc aatctaccag ccagtctcaa
    17461 aaaagctagt ttggctcaag ttgatttgga tgatttggga cgcttgccag tttttgaaaa
    17521 actattagcc tttgtggagc aatatccagc tattcgaaaa ggtctttact tatatggaga
    17581 ctttggtgtg ggtaaaagtt tcatggtggc ggccttagct catgatttat cagaaaaacg
    17641 tggtgtttca tcaactctcc tccactatcc tagctttgtc attgatgtca aaaatgctat
    17701 cagtgatggc aatgttaaga ccttggtgga tgagattaag ctgtctgagg tcctgatttt
    17761 agatgatatt ggcgccgagc aatcaaccgc ttgggtgcgt gacgaaatcc tgcaggtcat
    17821 tctccaatat cggatgcagg aaaatttacc gacctttttc acatccaact tcaactttga
    17881 agatttggag aagcattttg cgaaagtgaa acatggaaat gacgaaacct gggaagccag
    17941 acgggtcatg gaacgcatcc gttatttggc tgaggagact cgtttagaag gagtaaaccg
    18001 tcgatgacag aaaccattaa attgatgaag gctcatactt cagtgcgcag gtttaaagag
    18061 caagaaattc cccaagtaga cttaaatgag attttgacag cagcccagat ggcatcatct
    18121 tggaagaatt tccaatccta ctctgtgatt gtggtacgaa gtcaagagaa gaaagatgcc
    18181 ttgtatgaat tggtacctca agaagccatt cgccagtctg ctgttttcct tctctttgtc
    18241 ggagatttga accgagcaga aaagggagcc cgacttcata ccgacacctt ccaaccccaa
    18301 ggtgtggaag gtctcttgat tagttcggtc gatgcagctc ttgctggaca aaacgccttg
    18361 ttggcagctg aaagcttggg ctatggtggt gtgattatcg gtttggttcg atacaagtct
    18421 gaagaagtgg cagagctctt taacctacct gactacacct attctgtctt tgggatggca
    18481 ctgggtgtgc caaatcaaca tcatgatatg aaaccgagac tgccactaga gaatgttgtc
    18541 tttgaggaag aataccaaga acagtcaact gaggcaatcc aagcttatga ccgtgttcag
    18601 gctgactatg ctggggcgcg tgcgaccaca agctggagtc agcgcctagc agaacagttt
    18661 ggtcaagctg aaccaagctc aactagaaaa aatcttgaac agaagaaatt attgtagaaa
    18721 gtgagaaatt atggccctac caactattgc cattgtagga cgtcccaatg ttgggaaatc
    18781 aaccctattt aatcggatcg ctggtgagcg aatctccatt gtagaagatg tcgaaggagt
    18841 gacacgtgac cgtatttatg caacgggtga gtggctcaat cgttctttta gcatgattga
    18901 tacaggagga attgatgatg tcgatgctcc tttcatggaa caaatcaagc accaggcaga
    18961 aattgccatg gaagaagcag atgttatcgt ctttgtcgtg tccggtaagg aaggaattac
    19021 cgatgcagac gaatacgtag cccgtaagct ttataagacc cacaaaccag ttatcctcgc
    19081 agtcaacaag gtggacaacc ctgagatgag aaatgatatc tatgatttct atgctctcgg
    19141 tttgggtgaa ccattgccta tctcatctgt ccatggaatc ggtacagggg atgtgctaga
    19201 tgcgatcgta gaaaatcttc caaatgaata tgaggaagaa aatccagatg tcattaagtt
    19261 tagcttgatt ggtcgtccta acgttggaaa atcaagcttg atcaatgcta tcttgggaga
    19321 agaccgtgtt attgctagtc ctgttgctgg aacaactcgt gatgccattg atacccactt
    19381 tacagataca gatggtcaag agtttaccat gattgatacg gctggtatgc gtaagtctgg
    19441 taaggtttat gaaaatactg agaaatactc tgttatgcgt gccatgcgtg ctattgaccg
    19501 ttcagatgtg gtcttgatgg tcatcaatgc ggaagaaggc attcgtgagt acgacaagcg
    19561 tatcgcagga tttgcccatg aagctggtaa agggatgatt atcgtggtca acaagtggga
    19621 tacgcttgaa aaagataacc acactatgaa aaactgggaa gaagatatcc gtgagcagtt
    19681 ccaatacctg ccttacgcac cgattatctt tgtatcagct ttaaccaagc aacgtctcca
    19741 caaacttcct gagatgatta agcaaatcag cgaaagtcaa aatacacgta ttccatcagc
    19801 tgtcttgaac gatgtcatca tggatgccat tgccatcaac ccaacaccga cagacaaagg
    19861 aaaacgtctc aagattttct atgcgaccca agtggcaacc aaaccaccaa cctttgtcat
    19921 ctttgtcaat gaagaagaac tcatgcactt ttcttacctg cgtttcttgg aaaatcaaat
    19981 ccgcaaggcc tttgtttttg agggaacacc gattcatctc atcgcaagaa aacgcaaata
    20041 aaaaagtaga atctggaatg acagttccgg atttttttga tataataaaa taatagaaaa
    20101 cgctatcaaa agaaggaggg tgatgtcggt gatggaacat ttgtttaaat tcttactttt
    20161 agcaccgtac ttttattttg ataactggat tgagaaggcc aacagaaata gtaagttttt
    20221 tccaattttt tattattttt actggtttta catccccttc tattctcttt ttagccttgc
    20281 ttggacagtt gtttcagttc tgtttttcaa taccgtcttg agaaatgtga cagatatcaa
    20341 gttatggggc atttggtttc tttttattct gctagctatt ggtatgaatt ggttaactta
    20401 ttcctgtttc aaagaaatgt ttcgcttgag acaggaacta gggaagtcta agggtggaag
    20461 gcattgattt atatcggttt ctatttgtag gaggtggctt atggtacctc taaaatcatt
    20521 tattacacgc tattccaagg tttatattgg taataacatt taatagaacg aaactaaaga
    20581 aaacaattta aaagaggagg tttgtgatgg aatacttgtt taaaatgata atcttattac
    20641 cctgttttta ctttttcagc tggattgaaa aggcaaacag agatagtaag attttcccaa
    20701 ttttttacta tttttactgg atttacatca ccctctatgc tctttttagc cttgcttgga
    20761 cagttttttc agttctgttt ttcaatatcg tcttgagaaa tttgacagat atcaagttat
    20821 ggggtatttg gctattatta ctacttatcg cttttgctag tgactggtta gactatatct
    20881 gtttcaaaaa aatgcttgac ttgagacggg aactagggaa gtctaaaggc ggaaggcatt
    20941 gatttatact cttcgaaaat ctcttcaaac cacgtcaacg tcgccttgga ttatatatgt
    21001 aactgacttc gtcagtctta tctacaacct caaagcagtg ctttgagcaa cttgcggcta
    21061 gtttcctagt ttgctctttg attttcattg agtattatat tactttctat ttgtaggagg
    21121 tggcttatga agattcctct cttaactttg gcaaggcata aatttgttta tgtcttgctt
    21181 actttgcttt ttcttgcttt ggtttatcgt gatgttttga tgacttattt cttttttgat
    21241 attcatgcgc ccgatctagc taaattcgat ggacaagcaa ttaaaaatga cttattaaaa
    21301 tcagcattag attttcgtat tctccagttc aatctaggtt tttatcaatc atttattatt
    21361 ccaatcatca ttgttttgct aggttttcaa tatattgagc tgaaaaataa agttttacga
    21421 ttgagtattg gaagagaagt gagctatcaa gggttaaaaa gaaagttgac tttgcaagtt
    21481 gcaagtatcc cttgtttgat atatttagtg actgtgctga taattgcaat tataacctat
    21541 ttctttggga ctttttctcc tcttgaatgg aattctctat tttctgatgg gagtggttta
    21601 caaagactcc tagatggaga gataaaaagc tatttgttct ttacttgtgt cctactaatc
    21661 ggtattttca tcaatgcaat ctatttttta caaatagttg attatgtggg gaatgtgact
    21721 cgttcggcaa tcacctattt gatgtttctt tggcttggtt ctatgctgct ctatagtgcc
    21781 ttgccttact atatggttcc tatgacgagt ttgatgcaag ctagctatgg ggatgtaagt
    21841 ttgatgaaac tctttactcc ttatatcctt tatgttgtcc cttatatggt acttaaaaaa
    21901 tatgaagata atgtttaaga attttaacaa tatttggcta aagagaaaga tcgttttact
    21961 acttcgtata gttctgatga tgattttgat aaactatcta ttgtcaacag cggttcaaaa
    22021 gcaggatgct gttatctttt tcaagagaga attgatttca attttttcct ataatgacta
    22081 ttctgaagcg aatttagaaa tccccaaact cttgttaaac ctttcgcttt tcatggtagg
    22141 atggctctct gtcattttac ttgaaagtga tttggcagac cattaccatc acttgattcg
    22201 ctatcaatca agctcctttt tcgattatac aaggaaacga ttggttgtca tttctaaatt
    22261 ttttactcaa gatttgtttg tctggtttct tggtttactt ccgctaggaa ttcatttcaa
    22321 aacagtcgca cttttctttt tacttgctca gttaatgatg ttgtacttac tactgtctta
    22381 tctgatagca ctgattagtg cgggcgctgg tttttctttt tttctctatt ttttggcatt
    22441 tgtgggacaa gaatggatga tggatcatat tgtaacagtg tatttagtac tcttaagctt
    22501 attagttatg ttgattgtta gtcgcttgga agagaaattt aagaaaggat aaacgatgag
    22561 acttgaaatt ataaatggac agaaaattta tgggaaaaga cctattttaa atcagttgaa
    22621 tttggtgttt caatcaggaa aaatttatgg acttaaaggt gataatggat ctggcaagac
    22681 ggttctttta aagatacttg ctggttatat taagcttgac aaaggaaaag ttcttcaaga
    22741 tggtaaagtt tacggggtaa aaaatcatta tattcaggat gcaggaattt taattgaaaa
    22801 agtcgagttt ttatctcatt tatccctgag agaaaatttg gaactgttaa ggtatttttc
    22861 atctaaagtt acggaaaaaa gaattgccta ttggattcaa tactatgatt tacaggaatt
    22921 tgaagacgtt gaataccgtc atttatcctt gggaacaaag caaaaaatgg ccttgattca
    22981 agcctttatt tcctctcctt ctatactctt tctcgatgaa cctatgaatg ctttggatga
    23041 gaagagtgtg aggttaacca aacaggtcat tttatcttac ctgaaaaaag aaaatggtct
    23101 ggttatcctg acgtcgcaca tatcggaaga tatttcagac ctttgtacag atgtattagt
    23161 tgtcgaaaat ggacatatac aatatgtaaa ggatatacaa tcctaggaga tggcttatgg
    23221 cacatctaaa atcatttatt acacgctatt ccaaggttta tattggttta gttctgctga
    23281 tctggctgtc tttcttcttt atcccttggg atagagcgat tctgggggta aggattgaca
    23341 tcttcatcat gcagaaaatc ttgctagctt ttggaattct gtccattctc atggccttgc
    23401 tgtccaagaa agtcagtctc tttgtttttg gactgatttg ctgtctttct ctttggatta
    23461 acttatttat cacatttgcc attttgccga tttttggcaa ttaaacagtc ataaaagtcg
    23521 gagaggttag cttgaaaact aacctctttt tccttttcaa aatggggatt cttccttgaa
    23581 aataatcagt aattgtgcta aaattaaagg aacattctaa aatattcgga atttaaagta
    23641 aggaaaaaca tggctaatat tttaaaaaca attatcgaaa atgataaagg agaaatccgt
    23701 cgtctggaaa agatggctga caaggttttc aaatacgaag accaaatggc tactttgact
    23761 gacgaccaac taaaagcaaa aacagttgaa tttaaggaac gttatcaaaa tggagaatca
    23821 ctggattcat tgctttacga agcatttgcg gttgtccgtg aaggtgccaa acgtgtccta
    23881 ggtctcttcc cttataaggt tcaggtcatg ggggggattg ttcttcacca tggtgacgtg
    23941 ccagagatgc gtacagggga agggaaaacc ttgactgcga ccatgccggt atacctcaat
    24001 gccctttcag gtaaaggggt tcacgtagtt acggttaatg aatacctgtc agaacgtgac
    24061 gcgactgaga tgggtgaatt gtactcttgg cttggtttgt cagtagggat taacttggct
    24121 accaaatctc caatggagaa aaaagaagcc tatgagtgtg atattactta ctcaactaac
    24181 tcagaaatcg gatttgacta ccttcgtgac aacatggtcg ttcgcgccga aaacatggta
    24241 caacgtccgc ttaactatgc cttggtcgat gaggttgact ctatcttgat tgacgaggct
    24301 cgtacacctt tgattgtatc aggtgccaat gcggttgaaa ccagtcagtt gtatcacatg
    24361 gcagaccact atgtaaaatc tttgaacaaa gatgactaca tcatcgatgt gcagtctaag
    24421 actattggtt tgtctgattc agggattgac agggctgaaa gctacttcaa acttgaaaac
    24481 ctctatgaca tcgaaaacgt ggctttgact cactttatcg ataacgccct tcgtgccaac
    24541 tacatcatgc ttctcgatat tgactatgtg gtgagcgaag agcaagaaat cttgattgtc
    24601 gaccaattta caggtcgtac catggaaggt cgtcgttatt ctgatggatt gcaccaagct
    24661 attgaagcca aagaaggtgt gccaatccag gatgaaacca agacatctgc ctcaatcacg
    24721 taccaaaacc ttttccgtat gtacaagaaa ttgtctggta tgacgggtac aggtaagact
    24781 gaggaagaag aattccgtga aatctacaac attcgtgtta ttccaatccc aacaaaccgt
    24841 cctgttcaac gtattgacca ctcagacctt ctttatgcaa gtatcgaatc taagtttaaa
    24901 gcggttgtcg aagacgttaa ggctcgttac caaaagggtc aacctgtctt ggttggtaca
    24961 gtagcggttg aaactagtga ctacatttct aagaaattgg ttgcagctgg tgttcctcac
    25021 gaagtcttga atgccaaaaa ccactataga gaagcccaaa tcatcatgaa tgctggtcaa
    25081 cgtggtgccg ttaccatcgc aaccaacatg gcgggtcgtg gtaccgacat caagcttggt
    25141 gaaggtgttc gtgaacttgg aggactttgt gttattggta cagaacgtca tgaaagtcgt
    25201 cgtatcgata accagcttcg tggacgttca ggtcgtcaag gagatccagg tgagtcacaa
    25261 ttctacctat ctcttgaaga tgatttgatg aaacgttttg gttctgaacg cttgaaggga
    25321 atctttgaac gtttgaacat gtctgaagag gcgattgagt ctcgcatgtt gacgcgtcag
    25381 gttgaagcag ctcagaaacg tgtcgaagga aataactacg atacccgtaa acaagtcctt
    25441 caatacgatg atgtcatgcg tgaacaacgt gagattatct atgctcaacg ttacgatgtc
    25501 atcactgcag atcgtgactt ggcacctgaa attcaggcta tgatcaaacg cacgattgaa
    25561 cgtgtcgttg atggtcatgc gcgtgccaaa caagatgaaa aactagaggc aattttgaac
    25621 tttgctaagt acaacttgct tcctgaagat tctattacga tggaagactt gtcaggcttg
    25681 tctgataagg ccatcaagga agagcttttc caacgtgcct tgaaggttta cgatagtcag
    25741 gtttcaaaac tacgcgatga agaagcagtt aaagaattcc aaaaagtttt gattctacga
    25801 gtggtggata acaagtggac agatcatatc gatgcccttg atcaattgcg taacgcggtt
    25861 ggacttcgtg gctatgctca gaacaaccct gttgttgagt atcaggcaga aggtttccgt
    25921 atgtttaatg atatgattgg ttcgattgag tttgatgtga cacgcttgat gatgaaagca
    25981 caaattcatg aacaagaaag accacaggca gaacgtcata tcagtacaac agcgactcgc
    26041 aatatcgctg ctcaccaagc aagtatgcca gaagatttgg atttgagcca gattggacgc
    26101 aatgaacttt gcccatgtgg ttctggtaag aaatttaaaa actgtcacgg taaaagacaa
    26161 taaaatgaga tagtttagag gcggatatct tgtgaaaagt aaatttttac tgggtatccg
    26221 tttgctttat aaggagatga gttatggtat ttacagcaaa aagctctaaa ataaatatag
    26281 aagaagttcg tgccttgtca aaattagaag gtcaggcttt ggagaggaaa tcacagcgcg
    26341 atcaagagct agaagccatt atacgtggag aagatcagcg aattctcttg gtaatcgggc
    26401 catgctcatc tgacaacgaa gaagctgtcc ttgaatacgc taagcgtttg gcagtcctac
    26461 aagaagaagt ggcagatcgt atctttatgg ttatgcgtgt ttatactgcc aaaccccgta
    26521 ccaacggaga tggctataag ggcttgattc accagcctaa cgcgacagaa gcgcctagtc
    26581 ttatcaatgg aatcaaagcc gttcgccatc ttcactatcg tgtcatcaca gaaacaggga
    26641 tgacaactgc tgatgaaatg ctttatcctg aaaaccttcc gcttgtagat gatttgattt
    26701 cttacatggc agttggtgcc cgttcagttg aagaccagca acaccgcttt gtggcaagtg
    26761 gggcaggatt ttctactggt tttaaaaatc caacctctgg aaatctcaat gtcatgttta
    26821 atgggattta tgctgctcaa aacaaacaaa gtttcctttt cttaggaaaa gaagtagaaa
    26881 caactgggaa cccgctttca cacgctattc ttcgtggtgc tcttaatgag tatggaaaaa
    26941 atattcccaa ctactattat gacaatttaa ttgataccat tgcccaatat gagaaaatgg
    27001 gcttggaaaa tccttttatc atcattgata ccaatcatga caattctggt aagcagtata
    27061 ttgaacagat ccgaattgtc cgccagacct tgattaaccg tgcttggaat gaaaaaatta
    27121 agcagttcgt tcgtggtttt atgattgagt cttatctgga agatggtcga caaaatgagc
    27181 cagaagtatt tggcaagtct atcacagacc cttgcctggg ttgggataac acagaagctc
    27241 ttgtcagaga aatttacaaa acgttaggag aataagatgg catttattga aaaaggtcaa
    27301 gaaatcgata tggaagtcat caaggctgaa acccaattgt ctgcggaagc cttgagactc
    27361 aaggaaagcc gtgacaggga attggcagat attatttcag gggaagatga ccgtattctc
    27421 ttggtgattg gtccttgctc ttctgataat gaagaggcgg tcttggaata tgctcgccgt
    27481 ttatccgcct tgcaaaagaa ggtagcggac aagattttca tggtcatgcg cgtgtatact
    27541 gctaagcctc gtaccaatgg agacggctat aaaggattgg ttcaccagcc agatacttct
    27601 aaggctccaa gcctgattaa cggtttgcag gctgtgcgcc agttgcatta ccgcgtgatt
    27661 acagagactg gtttgacaac ggcagatgag atgctttatc cgtcaaatct gatcttggtg
    27721 gatgacttgg tcagctacca tgccgttgga gctcgttctg tggaagacca agagcaccgc
    27781 tttgtggctt ctgggattga tgcaccagta gggatgaaaa atccaacctc aggaaatttg
    27841 ggtgttatgt ttaacgccat ctatgctgct caaaacaagc aaaccttcct ttatcatggg
    27901 caggaagttg agacatcagg taatcctttg gcccatgtta tcctccgtgg agcagtcaac
    27961 gagtatggca attatatgcc gaattactac tatgaaaacc tactccaagc cattgaacgc
    28021 tatgaaacca tgggacttga aaatcctttt atcctcattg acaccaacca tgataactca
    28081 ggcaagcaat atatggagca gattcgaatt gttcgccaga ccttgcagaa tcgtgattgg
    28141 aatgagaaaa ttaaaaagac ggttcgagga tttatgattg aatcttacct agcagatggt
    28201 cgtcaaaacc aaccagagat ctttggttgc tctattactg acccttgcct aggttgggaa
    28261 aatacagagg ccttggtaga agagatttat gttaccttga caaaataagt gaaaaggatg
    28321 gagttgggga atctcaactc cttttgatga gaatgatagt tggacacgga attgacatcg
    28381 aagaattggc ttcgatagaa agcgcagtta cacgacatga aggatttgct aagcgtgtac
    28441 tgaccgctca ggaaatggag cgcttcacca gtctcaaagg acgcaggcaa atagaatatt
    28501 tagctggtcg ctggtcggct aaggaggcct tttccaaggc tatgggaacg ggcattagca
    28561 agctcggttt tcaggatttg gaagtattga acaatgaacg tggggcgcct tattttagtc
    28621 aggcaccatt ttcaggaaag atttggctgt ctatcagcca caccgatcag tttgtgacag
    28681 ccagtgtcat tttggaggaa aatcatgaaa gctagtccac atagaccaac caaggctctg
    28741 attcatctgg gagctattcg acaaaatatt cagcaaatgg gggctcatat ccctcaagga
    28801 acgctcaagt tggctgtggt taaggccaat gcttatggtc atggagctgt tgccgttgcc
    28861 aaggcaattc aagatgatgt tgatggcttt tgcgtttcca atatcgatga agccattgaa
    28921 ctcagacaag ctggactcag caagccaatc ctcattttag gagtttctga aatcgaagct
    28981 gttgctctag ctaaagaata tgacttcacc ttgacagtgg ctggactgga gtggattcaa
    29041 gcactcttag ataaggaagt ggacctaact ggattgacag tccacctcaa gattgattca
    29101 gggatgggac ggattggttt tagagaggca agtgaggttg agcaggctca agatttgctc
    29161 caacaacacg gtgttcgtgt tgaaggaatc tttacccact ttgctactgc tgatgaggaa
    29221 tcagatgact attttaatgc ccagttagaa cggtttaaaa ctattttagc tagtatgaag
    29281 gaagttccag agctggttca tgctagcaat tctgcaacga ctctttggca tgtagagact
    29341 attttcaatg cggttcgtat gggagatgcc atgtatggtc tcaatccaag tggagcggtc
    29401 ttggctttgc cttatgattt gataccggcc ttgaccttgg agtctgctct ggttcatatc
    29461 aagacagttc cagctggtgc ttgcatgggc tatggagcaa cttatcaaac ggatagcgag
    29521 caagtcatcg cgaccgtgcc aatcgggtat gcagatggat ggacaagaga catgcaaaat
    29581 ttctctgtct tggtagatgg ccaagcttgc ccaattgtcg gcagggtttc gatggaccaa
    29641 atcactattc gattgcctaa gccttaccca ctcggaacca aggtaacctt gattggctcc
    29701 aatggggata aggaaatcac tgcaactcag gtagcgacct accgcgtaac cattaactat
    29761 gaggtggttt gcctcctcag cgaccgtatt ccgagagaat attactagaa aagaaaggag
    29821 tggagcatga atctacatca acccttgcat gtcttgcctg gtgtgggacc aaagtcagca
    29881 gaaaaatacg ccaaactagg aattgaaaac ttgcaagatc tcttgctcta ctttcctttc
    29941 cgttatgaag acttcaaaat caagcaggtg ctggagctgg aagacggtga gaaggcagtt
    30001 ctttctggtc aggtagtgac tcctgctagt gtccagtatt atggtttcaa gcgcaatcgc
    30061 ctgcgtttta gtctcaagca gggagaggtc gtttttgcgg tgaatttctt taaccagccc
    30121 tatctggctg ataaaataga gttgggagca acccttgctg tctttggaaa atgggaccgc
    30181 gctaaggcta gtctgactgg gatgaaggtt ctggctcagg tagaagatga cctccagcct
    30241 gtctatcgtc tggctcaggg aatcagtcag gccagtctgg ttaaggtcat caagacggct
    30301 tttgatcagg gactggacct cttgatagaa gaaaatctgc cccagtcttt actagacaaa
    30361 tacaaactca tgtcccgttg tcaggcagtc cgagctatgc attttccaaa ggatttggca
    30421 gaatacaagc aggctcttcg ccgtatcaag tttgaggaac tcttttattt ccaaatgcag
    30481 ctgcagatgc tcaagtctga aaatagagtt cagggaagtg gtctggttct gaattggtct
    30541 caggaaaaag tgacagcagt taaagtaagt cttccttttg ccctgaccca agctcaggaa
    30601 aagagtttgc aggaaatttt aactgatatg aagtccgacc accacatgaa tcgtctccta
    30661 caaggggatg tggggagtgg aaaaacggta gtcgctggct tggccatgtt tgcggcagtg
    30721 acagcaggtt atcaggctgc cctaatggta ccaacagaaa tcctcgcaga gcaacacttt
    30781 gagagtttac agaacctttt tcccaatttg aaactggctc tcttgacagg ttccttgaaa
    30841 gctgcagaaa agagagaggt cttggagacc attgccaagg gtgaggctga tttgattatc
    30901 ggaactcacg ctctgataca agatggggtg gagtatgctc gtcttggttt gattattatc
    30961 gatgagcagc accgttttgg tgtagggcaa aggcgtattt tacgggaaaa aggtgacaat
    31021 ccagatgtcc tcatgatgac ggcgactccc attccacgga cgcttgccat cacagccttt
    31081 ggagatatgg atgtttccat tatcgaccag atgccagcag gtcggaagcc tattgtgacg
    31141 cgctggatca aacatgagca actacctcag gtcttgactt ggttagaggg ggaaattcaa
    31201 aaaggttccc aagcctatgt catctctcct ttgattgaag aatcagaagc tctagatttg
    31261 aaaaatgcca ttgccttatc agaggagttg acgactcatt ttgcaggcaa ggcagaggtg
    31321 gctcttctac atggtaggat gaagagtgac gaaaaagacc agatcatgca ggatttcaag
    31381 gagagaaaga cggatattct ggtttcgacg acggttattg aggttggggt caacgttccc
    31441 aatgcgactg tcatgattat catggatgcc gatcgcttcg gtctcagtca acttcaccag
    31501 cttagaggtc gtgtcggtcg gggggacaag cagtcctacg ctgttctcgt tgccaatccc
    31561 aagacggatt ctgggaaaga ccgcatgcgt atcatgacag aaacgaccaa tggatttgtc
    31621 cttgcggagg aagatttgaa aatgcgtggt tctggtgaga tttttggaac cagacagtca
    31681 ggacttccag agttccaagt ggctgatatt atcgaagatt ttccgatttt agaagaagca
    31741 agaaaggttg ctagctacat tagttctata gaagcttggc aagaagatcc agagtggcgc
    31801 atgattgccc ttcatctgga aaagaaagaa catctggatt aagctttctc taaggaaaac
    31861 ttaagctagt ttttaggttt ggctcttata ctaaagtcat caaaaagaaa cgaggactct
    31921 catatgacag taacgattaa agtaaattac caaaccactt tccaaaagaa ggaagcaaaa
    31981 aactagtata aacagaagag agagcgaaat gctctttttc gtttctaaaa ctactttcag
    32041 cccatcatcc taaaagtaaa gaatctaaat tcactttcta tttatccttc tttcttgcat
    32101 tgattacata gatatgctac agttgtggta acgattacaa aataaaagga gcatgctatg
    32161 aaaaatccag ctttgctaga agaaattaag acctatagag gaagggatga ggttccggaa
    32221 gactttgatg ctttctggga tggggaagtg aaaaatgttt ccacgcttcc atcctaccac
    32281 ttggaggaaa gagatttcca cattcctcaa gtcaagtgct atgagttaac atttgaagga
    32341 agcaaggaag gaaaggtcta tgcacgcatt gttcttccaa agagtgagga gaaggttcca
    32401 ctaatcttcc attttcatgg ttatatggga cgtggctggg actgggccga catgctgggc
    32461 ttcaccgtag ctggttacgg tgttgtttcc atggatgtgc ggggccagtc aggttactca
    32521 caagacggct tgcgttctcc tttaggaaat accgtgaagg ggcatattat ccgtggtgct
    32581 atggaaggtc gggaccacct cttttataag gatgtttatc tggatattta ccagttggtc
    32641 gaaattgttg ctagtctgtc tcaggttgat gagaagcgtc tttctagcta tggtgcctca
    32701 caaggagggg ctctagctct agttgcagca gcgctcaatc ctcgaattca gaaaacagtt
    32761 gccatttatc ccttcttgtc agacttcaga cgggtgattg agattggtaa tactagcgag
    32821 gcttacgacg aacttttccg ttatttcaag tttcacgacc ccttccatga aacagaggag
    32881 gaaatcatgg cgacccttgc ctatatcgat gtcaaaaatc ttgcccatcg tatccaaggt
    32941 gaggttaaga tgattacggg cttggacgac gatgtttgct atcccattac ccagtttgcg
    33001 atttataatc gtctgacctg cgataaaacc tatcgcatca tgcctgagta tgctcacgaa
    33061 gccatgaatg tatttgtcaa tgaccaagtc tacaactggc tctgtggaag tgagattcct
    33121 tttaaatatc taaaataagg agtcgactct aagcacaaaa tcttaaaaat tacaaacacg
    33181 catagtatca ggggattaaa aaaacttgat actatgcgtt ttatcatgga aatatagtaa
    33241 aatgaaacaa gaataggaca aaacgatcag gacagtcaaa tcgatttcta acaatgtttt
    33301 agaagcaaat gtgtactatt ctagtttcaa tctattatat ttatagaatt ttttgttgct
    33361 agatttgtca aattgcttaa aataattttt ttcagaaagc aaaagccgat acctatcgag
    33421 tagggtagtt cttgctatcg tcaggcttgt ctgtaggtgt taatactttt caaaaatctc
    33481 tttaaaccac gtcagcttcg ccttgccgta tatatgttac tgacttcgtc agttctatct
    33541 gccacctcaa aacggtgttt tgagctgact ttgtcagtct tatctacaac ctcaaaacag
    33601 tgttttgagc atcatgcggc tagcttctta gtttgctctt tgattttcat tgagtataaa
    33661 aacagatgag tttctgtttt ctttttatgg actataaatg ttcagctgaa actactttca
    33721 aggacattat tatataaaag aattttttga aactaaaatc tactatatta cactatattg
    33781 aaagcgtttt aaaaatgagg tataataaat ttactaacgc ttataaaaag tgatagaatc
    33841 tatctttatg tatatttaaa gatagattgc tgtaaaaata gtagtagcta tgcgaaataa
    33901 cagatagaga gaagggattg aagcttagaa aaggggaata atatgatatt taaggcattc
    33961 aagacaaaaa agcagagaaa aagacaagtt gaactacttt tgacagtttt tttcgacagt
    34021 tttctgattg atttatttct tcacttattt gggattgtcc cctttaagct ggataagatt
    34081 ctgattgtga gcttgattat atttcccatt atttctacaa gtatttatgc ttatgaaaag
    34141 ctatttgaaa aagtgttcga taaggattga gcaggaagta tggtataaat agcataagct
    34201 gatgtccatc atttgcttat aaagagatat tttagtttaa ttgcagcggt gtcctggtag
    34261 ataaactaga ttggcaggag tctgattgga gaaaggagag gggaaaattg gcaccaattt
    34321 gagatagttt gtttagttca tttttgtcat ttaaatgaac tgtagtaaaa gaaagttaat
    34381 aaaagacaaa ctaagtgcat tttctggagt aaatgtctta tttcagaaat cgggatatag
    34441 atatagagag gatcagtatg aatcggagtg ttcaagaacg taagtgtcgt tatagcatta
    34501 ggaaactatc ggtaggagcg gtttctatga ttgtaggagc agtggtattt ggaacgtctc
    34561 ctgttttagc tcaagaaggg gcaagtgagc aacctctggc aaatgaaact caactttcgg
    34621 gggagagctc aaccctaact gatacagaaa agagccagcc ttcttcagag actgaacttt
    34681 ctggcaataa gcaagaacaa gaaaggaaag ataagcaaga agaaaaaatt ccaagagatt
    34741 actatgcacg agatttggaa aatgtcgaaa cagtgataga aaaagaagat gttgaaacca
    34801 atgcttcaaa tggtcagaga gttgatttat caagtgaact agataaacta aagaaacttg
    34861 aaaacgcaac agttcacatg gagtttaagc cagatgccaa ggctccagca ttctataatc
    34921 tcttttctgt gtcaagtgct actaaaaaag atgagtactt cactatggca gtttacaata
    34981 atactgctac tctagagggg cgtggttcgg atgggaaaca gttttacaat aattacaacg
    35041 atgcaccctt aaaagttaaa ccaggtcagt ggaattctgt gactttcaca gttgaaaaac
    35101 cgacagcaga attgccaaat ggtcgagttc gcctgtatgt taatggtgtt ttatctcgaa
    35161 caagtctgaa atctggcaat ttcattaaag atatgccaga tgtaacgcat gtgcaaatcg
    35221 gagcaaccaa gcgtgccaac aatacggttt gggggtcaaa tctacagatt cggaatctca
    35281 ctgtgtataa tcgtgcttta acaccagaag aggtacaaaa acgtagtcaa ctttttaaac
    35341 gctcagattt agaaaaaaaa ctacctgaag gagcggcttt aacagagaaa acggacatat
    35401 tcgaaagcgg gcgtaacggt aaaccaaata aagatggaat caagagttat cgtattccag
    35461 cacttctcaa gacagataaa ggaactttga tcgcaggtgc agatgaacgc cgtctccatt
    35521 cgagtgactg gggtgatatc ggtatggtca tcagacgtag tgaagataat ggtaaaactt
    35581 ggggtaaccg agtaaccatt accaacttac gtgacaatcc aaaagcttct gacccatcga
    35641 tcggttcacc agtgaatatc gatatggtgt tggttcaaga tcctgaaacc aaacgaatct
    35701 tttctatcta tgacatgttc ccagaaggga agggaatctt tggaatgtct tcacaaaaag
    35761 aagaagccta caaaaaaatc gatggaaaaa cctatcaaat cctctatcgt gaaggagaaa
    35821 agggagctta taccattcga gaaaatggta ctgtctatac accagatggt aaggcgacag
    35881 actatcgcgt tgttgtagat cctgttaaac cagcctatag cgacaagggt gatctataca
    35941 agggtaacca attactaggc aatatctact tcacaacaaa caaaacttct ccatttagaa
    36001 ttgccaagga tagctatcta tggatgtcct acagtgatga cgacgggaag acatggtcag
    36061 cgcctcaaga tattactccg atggtcaaag ccgattggat gaaattcttg ggtgtaggtc
    36121 ctggaacagg aattgtactt cggaatgggc ctcacaaggg acggattttg ataccggttt
    36181 atacgactaa taatgtatct cacttaaatg gctcgcaatc ttctcgtgtc atctattcag
    36241 atgatcatgg aaaaacttgg catgctggag aagcggtcaa cgataaccgt caggtagacg
    36301 gtcaaaagat ccactcttct acgatgaaca atagacgtgc gcaaaataca gaatcaacgg
    36361 tggtacaact aaacaatgga gatgttaaac tctttatgcg tggtttgact ggagatcttc
    36421 aggttgctac aagtaaagac ggaggagtga cttgggagaa ggatatcaaa cgttatccac
    36481 aggttaaaga tgtctatgtt caaatgtctg ctatccatac gatgcataat ggaaaagaat
    36541 acattatcct cagcaatgca ggtggaccga atcgtgaaaa tgggatggtc cacttggcac
    36601 gtgtcgaaga aaatggtgag ttgacttggc tcaaacacaa tccaattcaa aaaggagagt
    36661 ttgcctataa ttcgctccaa gaattaggaa atggggagta tggcatcttg tatgaacata
    36721 ctgaaaaagg acaaaatgcc tataccctat catttagaaa atttaattgg gaatttttga
    36781 gcaaagatct gatttctcct accgaagcga aagtgaagcg aactagagag atgggcaaag
    36841 gagagatggg caaaggagtt attggcttgg agtttgactc agaagtattg gtcaacaagg
    36901 ctccaaccct tcaattggca aatggtaaaa cagcgacttt cctaacccag tatgatagca
    36961 aaaccttgtt gtttgcagta gataaggaag atatcggaca ggaaattatt ggtatagcta
    37021 aaggaagcat cgaaagtatg cataatcttc ctgtaaatct agcaggtgcc agagttcctg
    37081 gcggagtaaa tggtagcaaa gcagcggtgc atgaagttcc agaatttaca gggggagtta
    37141 atggtacaga gccagctgtt catgaaatcg cagagtataa gggatctgat tcgcttgtaa
    37201 ctcttactac aaaagaagat tatacttaca aagctcctct tgctcagcag gcacttcctg
    37261 aaacaggaaa caaggagagt gacctcctag cttcactagg actaacagct ttcttccttg
    37321 gtctgtttac gctagggaaa aagagagaac aataagagaa gaattctaaa catttgattt
    37381 tgtaaaaata gaaggagata gcaggttttc aagcctgcta tctttttttg atgacattca
    37441 ggctgatacg aaatcataag aggtctgaaa ctactttcag agtagtctgt tctataaaat
    37501 atagtagatt gaaataagat gtgaacaact ctatcaggaa agtcaaatta atttatagaa
    37561 aaattttagc agtcaaggtg tactgttata gattcaatat attatgtgac tattaacctt
    37621 ctcttctcct aaaattgact ttcttgtttt cttatcttgt ccactcgaaa caagtattgt
    37681 aagaatttga ttatttttga aagtactttt aatatacttg atatagttaa aaaagatttg
    37741 aaactaaatt ccaaattaga aaaagacttg aaatactaaa aaaaaaaagt atactctaat
    37801 tgaaaacggt aacaaaacta atttagagaa tgaaatatag agtatttctc tcttaaaagt
    37861 ttttggtgaa acgagatgta gaaaggagat ttagccaaag agtctattag tgctagaata
    37921 atagattaga attattttag aaaaacgaag tgagcagctt ataaattcaa gtccccaaat
    37981 agattcatac tagtatcttt tgcaaaaaat aaagggcgac ttccttcatg aatatcaatt
    38041 tcatctataa ggaaggtagc taattgaact aacttattta ttctgtttgt cgctagaaaa
    38101 atcagacctc cttgtgaaga ttgaggagat actgaatgaa aatcaaagaa gaaactagca
    38161 agctagtagc agattgccca aaacaccgcc ttgaggttgt agataagact gacctatata
    38221 atccaaggtg aagcgactgt ggtttgaaga gattttcaaa gagtataggc tagagagtag
    38281 tgtttttatg tccttctagt agaaaatgct agacagaaga atggggaact tggataggaa
    38341 aaatagattg agaaaggagg ttagaagaga tgattattac aaaaattagc catttaggaa
    38401 cttatgtggg agtaaatcca cattttgcaa cattaataga ttttctagaa aaaacaggac
    38461 tagaaaattt aacagaaggt tcgattgcta tcgatggtaa tcgattgttt gggaattgct
    38521 ttacttatct agcagatggt caagcagggg ctttctttga aacacaccaa aaatatttgg
    38581 atattcattt agttttggaa aacgaagaag ccatggctgt tacatcgccg gaaaatgtaa
    38641 gcgttaccca agaatatgat gaagagaaag atattgaatt atacacaggg aaagtggaac
    38701 agttggttca gttgagagct ggcgaatgcc tcatcacttt tccagaagat ttacatcaac
    38761 ccaaggttcg tataaatgat gaacctgtga aaaaagttgt ctttaaagtt gcgatttctt
    38821 aatgtagaaa gagaagaacg atgaaaaaaa tgagaaagtt tttatgtcta gctggaattg
    38881 cgctagcggc tgttgccttg gtagcttgtt caggaaaaaa agaagctaca actagtactg
    38941 aaccaccaac agaattatct ggtgagatta caatgtggca ctcctttact caaggacccc
    39001 gtttagaaag tattcaaaaa tcagcagatg ctttcatgca aaagcatcca aaaacgaaaa
    39061 tcaagattga aacattttct tggaatgact tctatactaa atggactaca ggtttagcaa
    39121 atggaaatgt gccagatatc agtacagctc ttcctaacca agtaatggaa atggtcaact
    39181 cagatgcttt ggttccgcta aatgattcta tcaagcgtat tggacaagat aaatttaacg
    39241 aaactgcctt aaatgaagca aaaatcggag atgattacta ctctgttcct ctttattcac
    39301 atgcacaagt catgtgggtt agaacagatt tgttaaaaga acataatatt gaggttccta
    39361 aaacttggga tcaactctat gaagcttcta aaaaattgaa agaagctgga gtttatggct
    39421 tgtctgttcc gtttggaaca aatgacttaa tggcaacacg tttcttgaac ttctacgtac
    39481 gtagtggtgg aggaagcctc ttaacaaaag atcttaaagc agacttgaca agccaacttg
    39541 ctcaagatgg tattaaatac tgggttaaat tgtataaaga aatctcacct caagattctt
    39601 tgaactttaa tgtccttcaa caagctacct tgttctatca aggaaaaaca gcatttgact
    39661 ttaactctgg cttccatatc ggaggaatta atgccaacag tcctcaattg attgattcga
    39721 ttgatgctta tcctattcca aaaatcaaag agtctgataa agaccaagga attgaaacct
    39781 caaacattcc aatggttgtt tggaaaaatt caaaacatcc agaagttgct aaagcattct
    39841 tagaagcact ttataatgaa gaagactacg ttaaattcct tgattcaact ccagtaggta
    39901 tgttgccaac tattaagggg attagcgatt ctgcagccta taaagaaaat gaaactcgta
    39961 agaagtttaa acatgctgaa gaagtaatta ctgaagctgt taaaaaaggt actgctattg
    40021 gttatgaaaa tggaccaagt gtacaagctg gtatgttgac taaccaacac attattgaac
    40081 aaatgttcca agatatcatt acaaatggaa cagatcctat gaaagcagca aaagaagcag
    40141 aaaaacaatt aaacgattta tttgaggctg ttcagtagat gtaaaagact agaaaatagg
    40201 tgggctagtg agctgaaaag ctctagccca atcttgtaaa agaagggaga aggagaatgg
    40261 ttaaagaacg taatttaact cgctggatat ttgttttgcc agctatgatt atcgtaggat
    40321 tactctttgt ttatccgttt ttctcgagta ttttttatag ctttaccaat aagcatttga
    40381 ttatgcctaa ttataaattt gttggtttgg ctaactataa agctgtgcta tcagatccca
    40441 acttctttaa tgcgttcttt aattcaatta agtggaccgt tttctcatta gttggtcaag
    40501 ttttagtagg gtttgtattg gctttagctc ttcacagagt acgccacttc aagaaattat
    40561 ataggacctt attgattgtt ccttgggcat ttcctaccat cgttattgcc ttttcttggc
    40621 agtggattct aaacggggtt tatggctact tacctaatct aatcgtaaaa ttaggtttaa
    40681 tggaacatac acctgcattt ttgacagata gtacatgggc attcctatgt ttggtgttta
    40741 tcaacatttg gtttggagca ccaatgatta tggttaatgt gctttcagct ttgcaaacag
    40801 taccagaaga acaatttgag gctgctaaga tagatggtgc ttcaagttgg caggtgttca
    40861 agtttatcgt ctttccacat attaaagtgg ttgtaggact tctagttgtt ttgagaactg
    40921 tatggatctt taataacttt gacattatct acctcattac tggtggtgga ccagccaatg
    40981 ctacaacgac gcttccaatt tttgcttaca acctgggctg gggaactaaa ttgttgggtc
    41041 gtgcttcagc agttacagta ttgctcttta tcttcttggt ggcgatttgc tttatctact
    41101 ttgctatcat cagtaagtgg gaaaaggagg gtagaaaata atgaagaaga aatccagtat
    41161 ttatttagat attctctcac atgtactttt agttggtgcg accatcgttg caattttccc
    41221 attggtatgg attatcatat cttctgtcaa agggaaaggg gaattaactc agtatccaac
    41281 acgattttgg cctgaacagt ttacattaga ttatttcact catgttatca acgatttgca
    41341 cttcattgat aacattcgaa acagtttaat cattgccttg gctacaaccc tcattgcgat
    41401 tattatttct gctatggcag cctatggtat tgttcgattc tttcctaaat tgggagcaat
    41461 catgtcgaga ctactcgtca ttacctacat tttcccacca attttgttag caattcccta
    41521 ttcaattgcc attgctaaag ttgggttaac aaatagttta tttggcttga tgatggttta
    41581 tctatctttt agtgttccat atgcagtttg gctcttagtt ggatttttcc aaacagttcc
    41641 aattggaatt gaagaagcgg ctagaattga tggtgcaaat aaatttgtta cgttttataa
    41701 agttgtgcta ccgattgtag caccaggtat tgtagcaaca gctatttata catttatcaa
    41761 tgcttggaat gaattcctgt atgccttgat tttgattaac aatacaggaa agatgacagt
    41821 agcagtagcc cttcgttcac ttaatggttc agaaatacta gactggggag atatgatggc
    41881 agcgtctgtt attgtagttc ttccatcaat tattttcttc tctatcatcc aaaataagat
    41941 tgcaagtgga ttatcagaag gatctgtgaa gtagacgaaa gaaggaaaaa aatgaataaa
    42001 agaggtcttt attcaaaact aggaatttct gttgtaggca ttagtctttt aatgggagtc
    42061 cccactttga ttcatgcgaa tgaattaaac tatggtcaac tgtccatatc tcctattttt
    42121 caaggaggct catatcaact gaacaataag agtatagata tcagcccttt gttattagat
    42181 aaattgtctg gagagagtca gacagtagta atgaaattta aagcagatga accaaactct
    42241 cttcaagctt tgtttggcct atctaatagt aaagcaggct ttaaaaataa ttacttttca
    42301 attttcatga gagattctgg tgagataggt gtagaaataa gagacgccca aaagggaata
    42361 aattatttat tttccagacc agcttcatta tggggaaaac ataaaggaca ggcagttgaa
    42421 aatacactag tatttgtatc tgattctaaa gataaaacat acacaatgta tgttaatgga
    42481 atagaagtgt tctctgaaac agttgataca tttttgccaa tttcaaatat aaatggtata
    42541 gataaggcaa cactaggagc tgttaatcgt gaaggcaagg aacattacct cgcaaaaaga
    42601 agtattgatg aaatcagtct atttaacaaa gcaattagtg atcaggaagt ttcaaatatt
    42661 cccttgtcaa atccatttca gttaattttc caatcaggag attctactca agctaactat
    42721 tttagaatac cgacactata tacattaagt agtggaagag ttctatcaag tattgatgca
    42781 cgttatggtg ggactcatga ttctaaaagt aagattaata ttgccacttc ttatagtgat
    42841 gataatggga aaacgtggag tgagccaatt tttgctatga agtttaatga ctatgaggag
    42901 cagttagttt actggccacg agataataaa ttaaagaata gtcaaattag tggaagtgct
    42961 tcattcatag attcatccat tgttgaagat aaaaaatctg ggaaaacgat attactagct
    43021 gatgttatgc ctgcgggtat tggaaataat aatgcaaata aagccgactc aggttttaaa
    43081 gaaataaatg gtcattatta tttaaaacta aagaagaatg gagataacga tttccgttat
    43141 acagttagag aaaatggtgt cgtttatgat gaaacaacta ataaacctac aaattatact
    43201 ataaatgata agtatgaagt tttggaggga ggaaagtctt taacagtcga acaatattcg
    43261 gttgattttg atagtggctc tttaagagaa aggcataatg gaaaacaggt tcctatgaat
    43321 gttttctaca aagattcgtt atttaaagtg actcctacta attatatagc aatgacaact
    43381 agtcagaata gagaagagag ttgggaacaa tttaagttgt tgcctccgtt cttaggagaa
    43441 aaacataatg gaacttactt gtgtcctgga caaggtttag cattaaaatc aagtaacaga
    43501 ttgatttttg caacatatac tagtggagaa ctaacctatc tcatttctga tgatagtggt
    43561 caaacatgga agaaatcctc agcttcaatt ccgtttaaaa atgcaacagc agaagcacaa
    43621 atggttgaac tgagagatgg tgtgattaga acattcttta gaaccactac aggtaagata
    43681 gcttatatga ctagtagaga ttctggagaa acatggtcgg aagtttcgta tattgatgga
    43741 atccaacaaa cttcatatgg cacacaagta tctgcaatta aatactctca attaattgat
    43801 ggaaaagaag cagtcatttt gagtacacca aattctagaa gtggccgtaa gggaggtcaa
    43861 ttagttgtcg gtttagtcaa taaagaagat gatagtattg attggaaata ccactatgat
    43921 attgatttgc cttcgtatgg ttatgcctat tctgcgatta cagaattgcc aaatcatcac
    43981 ataggtgtac tgtttgaaaa atatgattcg tggtcgagaa atgaattgca tttaagcaat
    44041 gtagttcagt atatagattt ggaaattaat gatttaacaa aataaaggag aaaaacatgg
    44101 ttaaatacgg tgttgttgga gcagggtatt ttggagctga attggctcgc tacatgcaaa
    44161 agaatgatgg agcagagatt actcttctct atgatccaga taatgcagag gcgattgcag
    44221 aagaattggg agcaaaagta gcaagttcct tagatgagtt ggtttctagc gatgaagtag
    44281 attgtgttat cgtcgcaact ccaaataatc ttcataagga accggttatt aaggctgcac
    44341 agcatggtaa aaatgttttc tgtgaaaaac caattgcgct ttcttatcaa gattgtcgcg
    44401 agatggtaga tgcgtgtaaa gaaaacaatg taacctttat ggcaggacat attatgaatt
    44461 tctttaatgg tgttcatcat gcaaaagaac tcattaatca aggagttatc ggagacgttc
    44521 tatattgtca tacagctcgt aatggttggg aagaacaaca accgtcagtg tcatggaaaa
    44581 aaattcgtga aaaatcaggt ggtcacttgt atcaccacat ccatgaattg gattgcgttc
    44641 aattccttat ggggggcatg cctgaaactg taaccatgac aggtggaaat gtggcccatg
    44701 aaggtgaaca tttcggtgat gaagatgata tgatttttgt caatatggaa ttttctaata
    44761 agcgttttgc cttgttagaa tggggttcag cttatcgttg gggtgaacat tatgtcttaa
    44821 tccaaggaag caaaggtgcc atccgcttag acttattcaa ctgtaaagga actcttaagc
    44881 tagatgggca agaaagctat ttcttgattc acgaatcgca agaagaagat gatgatcgga
    44941 ctcgtatcta tcatagtaca gagatggatg gagcaattgc ttatggtaaa ccaggtaaac
    45001 gtactccatt atggctatca tctgtcattg ataaagaaat gcgctatctg catgagatta
    45061 tggaaggagc tccagtatca gaagaatttg caaaactttt gacaggtgaa gctgccctag
    45121 aagcaattgc tactgcagat gcttgtaccc agtctatgtt tgaagatcgc aaagtaaaat
    45181 tgtcagaaat tgtaaaataa attttggtat tctcctattt ataggtcgac ttgctcctct
    45241 gaaagtactt ttagaggagc tgtttgactt tgctagtttt tgaaactgaa atctattata
    45301 ctacaaacta ttgaaagcgt tttaatttta aggtataata atctcataga aataaagaaa
    45361 aggaggaaag aggatgccac agattagcaa agaagccttg attgagcaaa tcaaagatgg
    45421 aatcatcgtt tcttgtcagg ctcttcctca tgaaccgctt tatacagaag cgggaggggt
    45481 gattcccttg ctggtcaaag cggctgagca aggtggagca gtcggtatcc gagcaaacag
    45541 tgttcgcgat atcaaggaaa ttaaggaagt cactaaactt ccaatcattg ggattatcaa
    45601 acgtgattat ccacctcagg aacccttcat cacggctact atgaaagaag ttgatgaatt
    45661 ggcagaactg gacatcgagg tgattgctct ggattgtacc aagcgtgaac gctacgatgg
    45721 tttggaaatt caagagttca ttcgtcaggt taaggagaaa tatcctaatc agcttttgat
    45781 ggctgatact agtatcttcg aagaagggct agcagctgta gaagcaggaa ttgactttgt
    45841 cggaacaacc ttatcaggct acacatccta cagtccaaaa gtagacggtc cagattttga
    45901 attgattaag aaactctgtg atgccggtgt agatgtcatt gcagaaggaa aaattcatac
    45961 accagaacaa gccaaacaaa tccttgaata tggagtgcga ggcatcgttg ttggtggcgc
    46021 cattactaga ccaaaagaga ttacagaacg cttcgttgct agtcttaaat aagatgtgag
    46081 ggggagtttt atgtttaaag ttttacaaaa agttggaaaa gcttttatgt tacctatagc
    46141 tatacttcct gcagcaggtc tacttttggg gattggtggt gcactttcaa acccaaccac
    46201 gatagcaact tatccaatac tagacaatag tatttttcaa tcaatattcc aagtaatgag
    46261 ctctgcagga gaggttgtat tcagtaattt gtcactactt ctctgtgtgg gattatgtat
    46321 tggcttagcg aaacgagata aaggaaccgc tgcgttagca ggagtaactg gttacttagt
    46381 tatgactgca acgatcaaag ctttagtaaa actttttatg gcagaaggat ctgcaattga
    46441 tactggagtt attggagcat tagttgtcgg aatagttgcc gtatatttgc acaaccgata
    46501 taacaatatt caattacctt ccgctttagg attctttgga ggttcacgct tcgttcctat
    46561 tgttacatcg ttctcttcta tcttgattgg ctttgtcttc tttgttattt ggccaccttt
    46621 ccaacaactt cttgtttcta caggtggata tatttctcag gcgggtccaa ttggaacttt
    46681 tctatatgga tttttaatga gactttctgg agcagtaggc ttacatcata taatttaccc
    46741 tatgttttgg tatactgaac ttggtggtgt tgaaactgtt gcaggacaaa cagtggttgg
    46801 agctcaaaaa atattttttg ctcaattagc cgatttggcc cattctggat tatttacaga
    46861 aggaacaagg ttttttgcag gtcgtttctc aacaatgatg ttcggtttac cggctgcctg
    46921 tttagcgatg taccatagtg ttcctaaaaa tcgtcgtaaa aaatacgcgg gtttgttttt
    46981 gggagttgct ttaacatctt ttattaccgg tattacagaa ccaattgaat ttatgtttct
    47041 attcgttagt ccggttctat atgttgttca cgcattcctt gatggtgtta gcttctttat
    47101 tgcagacgtc ttaaatattt caataggaaa cacattttca ggaggtgtaa tcgatttcac
    47161 tttatttgga attttgcagg ggaacgctaa gacgaattgg gttcttcaga ttccatttgg
    47221 acttatttgg agtgttttgt attatattat ttttagatgg ttcattactc aattcaacgt
    47281 tctaacgcca gggcgaggag aagaagtaga ttctaaagaa atttctgaat ccgcagattc
    47341 aacttcaaat actgcagatt atttaaaaca ggatagccta caaattatca gagccttggg
    47401 tggatcaaat aatatagaag atgtagatgc ttgtgtgaca cgtttacgtg tagctgtaaa
    47461 agaagttaat caagttgata aagcactttt aaaacaaatt ggtgcagttg atgtcttaga
    47521 agtgaagggt ggcattcaag caatatatgg agcaaaagca atcttatata aaaatagtat
    47581 taatgaaatt ttaggtgtag atgattaagt acttactgac ttaataaaaa acagaggaga
    47641 gtgatggatg agtaggatga aatgaaatcg catacaagaa ataaagaact cattatccaa
    47701 gttggatacg cttattacat aggagaatac aaatgaaatt tagaaaatta gcttgtacag
    47761 tacttgcggg tgctgcggtt cttggtcttg ctgcttgtgg caattctggc ggaagtaaag
    47821 atgctgccaa atcaggtggt gacggtgcca aaacagaaat cacttggtgg gcattcccag
    47881 tatttaccca agaaaaaact ggtgacggtg ttggaactta tgaaaaatca atcatcgaag
    47941 cgtttgaaaa agcaaaccca gatataaaag tgaaattgga aaccatcgac ttcaagtcag
    48001 gtcctgaaaa aatcacaaca gccatcgaag caggaacagc tccagacgta ctctttgatg
    48061 caccaggacg tatcatccaa tacggtaaaa acggtaaatt ggctgagttg aacgacctct
    48121 tcacagatga atttgttaaa gatgtcaaca atgaaaacat cgtacaagca agtaaagctg
    48181 gagacaaggc ttatatgtat ccgattagtt ctgccccatt ctacatggca atgaacaaga
    48241 aaatgttaga agatgctgga gtagcaaacc ttgtaaaaga aggttggaca actgatgatt
    48301 ttgaaaaagt attgaaagca cttaaagaca agggttacac accaggttca ttgttcagtt
    48361 ctggtcaagg gggagaccaa ggaacacgtg cctttatctc taacctttat agcggttctg
    48421 taacagatga aaaagttagc aaatatacaa ctgatgatcc taaattcgtc aaaggtcttg
    48481 aaaaagcaac tagctggatt aaagacaatt tgatcaataa tggttcacaa tttgacggtg
    48541 gggcagatat ccaaaacttt gccaacggtc aaacatctta cacaatcctt tgggcaccag
    48601 ctcaaaatgg tatccaagct aaacttttag aagcaagtaa ggtagaagtg gtagaagtac
    48661 cattcccatc agacgaaggt aagccagctc ttgaatacct tgtaaacgga tttgcagtat
    48721 tcaacaataa agacgacaag aaagtcgctg catctaagaa attcatccag tttatcgcag
    48781 atgacaaaga gtggggacct aaagacgtag ttcgtacagg tgctttccca gtccgtactt
    48841 catttggaaa actttatgaa gacaaacgca tggaaacaat cagcggctgg actcaatact
    48901 actcaccata ctacaacact attgatggtt ttgctgaaat gagaacactt tggttcccaa
    48961 tgttgcaatc tgtatcaaat ggtgacgaaa aaccagcgga tgctttgaaa gccttcactg
    49021 aaaaagcaaa cgaaacaatc aaaaaagcta tgaaacaata gtccttagtt attctataaa
    49081 aagtagtttt ttaaagaacc taagagtgta tacccccttt tccctctaca cagatagtgt
    49141 aagaaaaggg ggcttttgtt taaaatgtaa gaaactgtca cgaaattaaa atgaagttct
    49201 tacataagcg aatcataaaa aatttcattt tgattttaaa acagttcaag aaagtcaaaa
    49261 aattattcta tttgaaagag aggtgccgac tgtgaaagtc aataaaatcc gtatgcggga
    49321 aacagtgatt tcctacgctt tcctagcacc agtattattc ttctttgtca tctttgtgtt
    49381 ggctccgatg gtgatgggct tcattacaag tttctttaac tactcaatga ctaaatttga
    49441 gtttgtaggc ttggataact atatccgtat gtttaaagat cctgtcttta caaaatctct
    49501 gattaacaca gttattttgg ttattggatc tgtaccagtt gttgttctat tctcactctt
    49561 tgtagcatct cagacctatc atcaaaatgt cattgccaga tccttctacc gtttcgtctt
    49621 cttccttcct gttgtaacgg gtagtgttgc cgtgacagtt gtttggaaat ggatttatga
    49681 cccactatca gggattctaa actttgtcct taagtccagc cacatcatca gccaaaacat
    49741 ttcttggttg ggagataaaa actgggcatt gatggcgatt atgattattc tcttgaccac
    49801 ttcagttggt cagcccatca tcctttatat cgctgccatg gggaatattg acaattcact
    49861 ggttgaagcg gcgcgtgttg atggtgcaac tgagtttcaa gttttttgga agattaaatg
    49921 gccaagcctt cttccaacaa ctctttatat tgcaatcatc acaacaatta actcattcca
    49981 gtgtttcgcc ttgattcagc ttttgacatc tggtggtcca aactactcaa caagtacctt
    50041 gatgtactac ctttacgaaa aagccttcca attgacagaa tacggctatg ccaacacaat
    50101 tggtgtcttc ttggcagtca tgattgctat cgtaagcttt gttcaattta aagtacttgg
    50161 aaacgacgta gaatactaaa gaaaggagac agctatgcaa tctacagaaa aaaaaccatt
    50221 aacagccttt actgttattt caacaatcat tttgctcttg ttgactgtgc tgttcatctt
    50281 tccattctac tggattttga caggggcatt caaatcacaa cctgatacaa ttgttattcc
    50341 tcctcagtgg ttccctaaaa tgccaaccat ggaaaacttc caacaactca tggtgcagaa
    50401 ccctgccttg caatggatgt ggaactcagt atttatctca ttggtaacca tgttcttagt
    50461 ttgtgcaacc tcatctctag caggttatgt attggctaaa aaacgtttct atggtcaacg
    50521 cattctattt gctatcttta tcgctgctat ggcgcttcca aaacaagttg tccttgtacc
    50581 attggtacgt atcgtcaact tcatgggaat ccacgatact ctctgggcag ttatcttgcc
    50641 tttgattgga tggccattcg gtgtcttcct catgaaacaa tttagtgaaa atattcctac
    50701 agagttgctt gaatcagcta aaatcgacgg ttgtggtgag attcgtacct tctggagtgt
    50761 agccttcccg attgtgaaac cagggtttgc agcccttgca atctttacct tcatcaatac
    50821 ttggaatgac tacttcatgc agttggtaat gttgacttca cgtaacaatt tgaccatctc
    50881 acttggggtt gcgaccatgc aggctgaaat ggcaaccaac tatggtttga ttatggcagg
    50941 agctgccctt gctgctgttc caatcgtcac agtcttcctt gtcttccaaa aatccttcac
    51001 acagggtatt actatgggag cggtcaaagg ataatactct gcgaaaatcg aatgcaaact
    51061 acgtcagctt caccttgcca tacttaagta ttgcctgcgg ttagcttcct agtttgttct
    51121 tcaattttca ttgagtatag gaaaatcaat ctatcaagat acagaagtat attttataga
    51181 tttagagaat atagaagtta taagtgtcta caaaatggag ggtatgcagt tactttatga
    51241 agttttgtca gacacttatc aacttaagaa tgattttagt taattatcag aaacgaagga
    51301 aagagtatga tttttgacga tttgaaaaac atcacctttt acaaagggat tcatcccaat
    51361 ttagacaaag ctatcgacta cctctaccaa catcgtaaag attcattcga attaggaaag
    51421 tatgagattg atggagataa ggtctttcta gttgttcagg aaaatgtcct caatcaagtt
    51481 gagaataatc aatttgaaca ccataagaac tatgcagatt tgcatttgct gatagaaggg
    51541 catgaatatt cgagctacgg ttcacgtatc aaagacgagg cagtagcatt cgacgaagcg
    51601 actgacattg gctttgttca ttgtcatgaa cactacccac tcttgttggg ttatcataat
    51661 tttgcgattt tcttcccagg tgagccacat cagccaactg gctatgcagg tatggaagaa
    51721 aaggttcgaa aatatctctt taaaattttg attgattaaa aataggatga attgtttttt
    51781 tgtaaagctt tgacaatact ctaccatgaa attgatcttt atgaggtaga gaaatgagaa
    51841 taaaatattt aaaaattggt atcttctaag catgctgcaa gagctagttt cttagatgga
    51901 caggaaatta cagttgatga gatgtcctgg ataattaatg gcattgtgaa tgcattgatt
    51961 ggtagataca taaaattagg tacttatgca gctaagtatg gtattggtat agcacgctcg
    52021 atcttaagta gggcagctgc aactgcagca gcaagagtag gattactgac caagatttct
    52081 ggatggattt tacgagtagc tgtgaatgta gctgatgtat atggtaattt cgccaacaat
    52141 attgctgcag cttgggatgc atatgataaa attcctaaca atggtcgtat aaacttttaa
    52201 aatacgagaa tgaaagcact ttgtattttt ttattgaata tgttagcttg gacagtgctt
    52261 gcaatgataa ttcgtggagg gctagatgga tttgataggc atacttggag tactatttta
    52321 attgcttcgc tgttcggggt atatgattat aagcccatag ataaaaatag aaaaaagtcc
    52381 aaaagaaaaa agaaaaaata gatttgttca tggtagggac ttatgaaagc tttactgaca
    52441 aaaaagaaaa cagtttacaa agaaaaatga tggaggagca aacatggcac aaaaaggagt
    52501 aagccttatc aaggcagcat ttgatacaga taactttctc atgcgtttta gtgagaaggt
    52561 cttggacatc gtgacagcca atcttctttt tgtcgtctct tgtttaccca tcgtgacgat
    52621 tggagtggct aaaatcagcc tctacgagac catgttcgaa gttaagaaga gcagacgggt
    52681 gcctgttttt aaaatctatc taagatcttt caagcaaaat ctgaaactag gtcttcagct
    52741 gggtttaatg gagttaggaa ttgtgtttct taccctttca gatctctatc ttttctgggg
    52801 tcaaacagct ctgcccttcc aattgctgaa agccatttgt ttaggtattc tgatttttct
    52861 tactatcgtg atgctggcta gttaccctat cgcggcacgt tatgacctat cttggaaaga
    52921 aattcttcaa aaaggattga tgttggctag ttttaacttt ccttggttct tcctcatgtt
    52981 agccattctt gtcctcattg tgatggttct ttatctgtcc gccttcagtc tactcttagg
    53041 tggctcagtc ttcctacttt ttgggtttgg actattggtc tttatccaga ctggattgat
    53101 ggagaaaatt ttcgcaaaat accaatagga gctttatttc tgaaactact ttcaaaggct
    53161 ccaaacgcta ttctataagc gagaaactaa aatctaagtg tctataagat attgaaagcc
    53221 ttttcggtaa agtgtatact aaagaagtaa agaaaaatct gctttagcag aaaataaaaa
    53281 taataggaga aaatctatgt cagatttgaa aaaatacgaa ggtgtcattc cagccttcta
    53341 cgcatgttat gatgagcaag gagaagtaag tccagagcgt acgcgtgcct tggttcaata
    53401 cttcattgat aaaggtgttc aaggtcttta tgtcaatggt tcttctggtg aatgtatcta
    53461 ccaaagcgtt gaagatcgca agttgatttt ggaagaagtc atggcggtag ctaaaggtaa
    53521 attgaccatt attgcccatg ttgcctgcaa caatactaaa gacagtatgg aacttgctcg
    53581 ccatgctgaa agcttgggag tagatgctat tgcaacgatt ccaccaattt atttccgctt
    53641 gccagaatac tcagttgcca aatactggaa cgatatcagt tctgcagctc caaacacaga
    53701 ctacgtgatt tacaacattc ctcaattggc aggggttgct ttgactccaa gcctttacac
    53761 agaaatgttg aaaaatcctc gtgttatcgg tgtgaagaac tcttctatgc cagttcaaga
    53821 tatccaaacc tttgtcagcc ttggtgggga agaccatatc gtctttaacg gtccagatga
    53881 acagttccta ggtggtcgcc tcatgggtgc caaagctggt atcggtggta cttatggtgc
    53941 tatgccagaa ctcttcttga aactcaacca attgattgcg gataaagatt tagaaacagc
    54001 gcgtgagtta cagtatgcta tcaacgctat cattggtaaa ttgactgcta cacatggaaa
    54061 tatgtacggt gtcatcaaag aagttttgaa gatcaatgaa ggcttgaata ttggttctgt
    54121 tcgttcacca ttgacaccag tgactgaaga agatcgtcca gttgtagaag cggctgctgc
    54181 cttgattcgt gaaaccaagg agagcttcct ctaatctaaa aggaggtatt tatgacatac
    54241 tacgttgcaa ttgatatcgg tggaaccaac atcaagtatg gtttggttga tcaagagggg
    54301 caacttcttg aatcgcatga aatgccaact gaggcgcata agggtggacc tcatatctta
    54361 caaaagacca aagatatcgt agctagttat ttagaaaaag gcccagtagc aggtgttgcc
    54421 atatcttctg ctgggatggt ggatccggat aagggtgaga ttttctatgc tgggccgcaa
    54481 atccctaact acgcaggcac ccagttcaaa aaggaaatcg aagaaagctt tactattcct
    54541 tgtgagattg aaaatgatgt caactgtgca ggtcttgctg aggcagtatc tggttcaggc
    54601 aagggagcaa gtgtgacact ttgcttgacc attggaaccg gtatcggtgg ttgcttgatt
    54661 atggatagga aagtcttcca tggttttagc aattcagcct gtgaagtcgg gtatatgcat
    54721 atgcaggatg gagcttttca agacttggct tctacaacag ctttagtgaa atatgtagct
    54781 gaagcccatg gagaagatgt tgatcagtgg aatggccgta gaattttcaa agaagccact
    54841 gaaggaaaca aaatctgcat ggaaggtatt gaccgtatgg ttgactatct aggaaaaggt
    54901 ctggcaaata tttgctacgt tgccaatcca gaagtggtta ttcttggtgg tggtatcatg
    54961 gggcaagagg ctatcctcaa acctaagatc cgcacagcct tgaaagaggc tttggtacca
    55021 agtttagcag aaaaaacacg attagaattt gcccatcacc aaaatacagc agggatgttg
    55081 ggtgcatatt atcattttaa gacaaaacaa tcctagtttg gctcagccaa actaggattt
    55141 tcttacacgt ttttgtctac gatagccgtt gagtttttta ttttcccagt agctattaaa
    55201 gattttttcc ttgctttcgc gattgatttc caaaaagtag gcataaatca aatcgataaa
    55261 gaagagcata ggaagttgag cggatattcg ttggatatag gagggttggc tgtgggtggc
    55321 tacaagaaca gtctctgtat aggtctggct atctttattg ggaacacttg taaagagtac
    55381 agtctttgcc cccatctcct tggcatctaa tagactatct aaaatagaag gagttgagcc
    55441 tgaaagtgag aagcccagta ctagacaatt ttcatccatg atgctggttg tccaggcaaa
    55501 gccgtcttgg tctgtcaaag cttcgcagac cacacctagt cgcataaaac gtaatttcat
    55561 ttcacgggcg acgaggccag aactccctgt tccaaagaag tagatacgct cagcatcttc
    55621 gattagctgg gcaattcgct ctagttggat ttcgtcaatc aagtcttgtg tttgttccct
    55681 catattgcta taacttctga ggactcgttt ggtcagtgga ctgtgcttgg agactcggtt
    55741 ggcttgattt tctgcctgat gttggtattg gaaaataaat tctcggtagc cagtaaagcc
    55801 acacttttta gcaaagcggg tcaaagcagc ttgagaaata tgtaattttt gggtgacttg
    55861 ttgagaagat aaatcatctg taatcgtttc agcttgcaaa aaatagcgag cgatttcttg
    55921 ctctaggtct gtcatttctt caaaatgtga atcaatgata gttgcgatat ctggtttgtc
    55981 catagggaaa gctcctttac atgagtcata ctggaagact agatcaggga atagtcacac
    56041 ttcattataa cacataatat aaggatagat aaataaaaac gcatctctgt tttaaaaacg
    56101 aaaaaatcga aaaagcttct ctcttttcca taattttcta ctcaaattgt ggtacaatta
    56161 agagtaagat tttaagttag aaatgagact gatttgtatg agaaaattta acagccattc
    56221 gattccgatt cggcttaatt tattgttttc aatcgtcatt ttactcttta tgaccattat
    56281 tggtcgtttg ttgtatatgc aggttttgaa caaggatttt tacgaaaaaa agctagcctc
    56341 agctagtcag accaagatta caagcagttc agcccgtggg gaaatttatg atgctagtgg
    56401 aaaacctttg gtagaaaata cgttaaagca ggttgtttcc tttacgcgta gcaataaaat
    56461 gacggctaca gacttaaaag aaacagctaa aaagttactg acttatgtga gcatcagttc
    56521 tccaaatttg acaaaacgcc agctggcgga ttactatttg gctgatcctg aaatctataa
    56581 aaaaacagtg gaagctctcc caagcgagaa acgcttggat tcagatggca atcgtctatc
    56641 cgaatcagaa ctgtataaca atgcggtcga tagtgtccaa acaagtcaac taaactatac
    56701 agaggatgaa aagaaagaaa tctatctttt tagtcagtta aatgctgttg gaaactttgc
    56761 gacaggaacc attgctacag atcctctaaa tgattctcag gtggctgtta ttgcctctat
    56821 ttcaaaggag atgcctggca ttagtatttc tacttcttgg gatagaaagg ttttggaaac
    56881 ttccctttct tctatagttg ggagtgtatc cagtgaaaaa gctggtctcc cagcggaaga
    56941 agcagaagcc tatcttaaaa aaggctattc tctaaatgac cgtgtaggaa cctcctattt
    57001 ggaaaagcaa tatgaagaga ccttacaagg aaaacgatcg gtaaaagaaa tccatctgga
    57061 taaatatggc aatatggaaa gcgtggatac aattgaggaa ggtagtaagg gaaacaatat
    57121 caaactgacc attgatttgg ccttccaaga tagcgtggat gctttgctga aaagttattt
    57181 caattctgag ctagaaaatg gtggagccaa gtattctgaa ggtgtctatg cagtcgccct
    57241 taacccaaaa acaggtgcgg ttttgtctat gtcagggatt aaacatgact tgaaaacggg
    57301 agagttgacg cctgattcct tgggaacggt aaccaatgtc tttgttccag gttcggttgt
    57361 caaggcggcg accatcagct caggttggga aaatggagtc ttgtcaggaa accagacctt
    57421 gacagaccag tccattgtct tccaaggttc agctcccatc aattcttggt atactcaggc
    57481 ttacggttca ttccctatca cagcggtcca agctctggag tattcatcaa atacctatat
    57541 ggtccaaaca gccttaggtc ttatggggca aacctatcaa cccaatatgt ttgtcggcac
    57601 cagcaatcta gagtctgcta tggagaaact gcgttcaacc tttggcgaat atggcttggg
    57661 tactgcgaca ggaattgacc taccagatga atctactgga tttgttccca aagagtatag
    57721 ctttgctaat tacattacta atgcctttgg gcagtttgat aactatacgc cgatgcagtt
    57781 ggctcagtat gtagcaacta ttgcaaataa tggtgttcgt gtggctcctc gtattgttga
    57841 aggcatttat ggtaataatg ataagggagg actgggtgac ttgattcagc aactgcaacc
    57901 gacagagata aataaggtca atatatccga ctccgatatg agcatcttgc accaaggttt
    57961 ttatcaggtt gcccatggta ctagtggatt gacaactgga cgtgcctttt caaatggtgc
    58021 cttggtatcc attagcggaa aaacaggtac agccgaaagc tatgtggcag atggtcagca
    58081 agcaaccaat accaatgcgg tggcctatgc cccatctgat aatccccaaa tcgctgtcgc
    58141 agtggtcttt cctcataata ccaatctaac aaatggtgta ggaccttcca ttgcgcgtga
    58201 cattatcaat ctgtatcaaa aataccatcc aatgaactag aaaggaaatt atgctttatc
    58261 caacacctat tgccaagttg attgacagtt attctaagtt accaggtatc gggattaaga
    58321 cggctacgcg tctggccttt tatacgattg ggatgtctgc tgatgatgtc aatgaatttg
    58381 caaaaaatct cctttctgct aagagagaat tgacatattg ttctatttgt ggacgtttga
    58441 cagacgacga tccttgttct atctgtactg atccgactcg tgaccagaca acaattttag
    58501 ttcttgagga tagtagagat gtggcagcca tggaaaatat ccaagaatac catggactct
    58561 atcatgtcct gcatggcctc atttctccta tgaatggtat cagtccggac gatatcaatc
    58621 tcaagagcct tatgactcgt cttatggata gtgaggtttc agaagtgatt gtggcgacta
    58681 atgctacagc ggatggtgaa gcgacttcca tgtatctttc acgtttgctc aagccagctg
    58741 gtatcaaggt tacgcgtcta gcacgaggtc tcgctgtggg agcggacatt gagtatgcgg
    58801 acgaagtgac actcttacga gcgattgaaa atcggacaga gttgtaagtg taggcaaatt
    58861 tacgaactcc cttcatttat aaaaaatcaa agaggctgaa aatcgttcct atcggcctct
    58921 ttttgtatag tgtgatgagt aggatcgggt tcaagtttta aaaaaccaag caaatatgat
    58981 atactaaaga gcgagtattc tagtagaatt aggacaaata atatgaaaca aacgattatt
    59041 cttttatatg gtggacggag tgcggaacgc gaagtctctg tcctttcagc tgagagtgtc
    59101 atgcgtgcgg tcaattacga ccgtttcaca gtcaagactt tctttatcag tcagtcaggt
    59161 gactttatca aaacacagga atttagtcat gctccggggc aagaagaccg tctcatgacc
    59221 aatgaaacca ttgattggga taagaaagtt gcaccaagtg ctatctacga agaaggtgca
    59281 gtggtctttc cagtccttca cgggccaatg ggagaagatg gctctgttca aggattcttg
    59341 gaagttttga aaatgcctta cgttggttgc aacattttgt catcaagtct tgccatggat
    59401 aaaatcacga ctaagcgtgt tctggaatct gctggtattg cccaagttcc ttatgtggct
    59461 atcgttgaag gcgatgatgt gactgctaaa atcgctgaag tggaagaaaa attggcttat
    59521 ccagtcttca ctaagccgtc aaacatgggg tctagtgtcg gtatttctaa gtctgaaaac
    59581 caagaagaac tccgtcaagc cttaaaactt gccttccgat atgacagccg tgtcttggtt
    59641 gagcaaggag tgaatgcccg tgaaattgag gttggcctct tgggtaacta cgatgtcaag
    59701 agcacgctac ctggagaagt tgtcaaggac gttgcctttt atgactacga tgccaagtat
    59761 attgataaca agattactat ggatattcct gccaaaatca gtgatgatgt ggtagctgtc
    59821 atgcgtcaaa atgcagaaac agccttccgt gccattggtg gccttggtct atctcgttgc
    59881 gatttcttct atacagataa gggagagatt tttctcaacg agctcaatac catgccaggt
    59941 ttcacccagt ggtctatgta cccactactt tgggacaata tggggatcag ctacccagaa
    60001 ctaatcgagc gtttggttga ccttgccaag gaaagttttg acaagcgcga agcgcatttg
    60061 atataaaatg aaagagaggg tagaagccag aaccatcact gcaaggtgac tagagttctc
    60121 ggacttcagc cctttttaaa ggagtagaaa tgaaattaac aatccatgaa gttgcccaag
    60181 ttgttggagc caaaaatgat atcagtatct ttgaggacac ccagttagaa aaagctgagt
    60241 ttgatagtcg tttgattgga actggagatt tatttgtgcc cctaaaaggt gtgcgtgacg
    60301 gtcatgactt tatcgaaaga gcttttgaaa atggtgcggc agcaaccctg tctgagaaag
    60361 aggttgcaaa tcatccctac attctagtag atgatgtttt gactgccttt caacaactag
    60421 ctgcctacta tcttgaaaaa acagctgttg atgtctttgc ggttacgggt tcaaatggca
    60481 agacaacgac taaggatatg ttggcgcatt tactgtcaac aagatacaag acctacaaaa
    60541 cacaaggcaa ttacaataat gagattggcc ttccttacac agttctccac atgcctgaag
    60601 gaacagaaaa gttggtcttg gagatggggc aggaccactt gggagatatt catctcttgt
    60661 ctgaattggc tcgtccaaaa acagccatcg tgaccttggt tggagaagct catttggcct
    60721 ttttcaaaga tcgttctgag attgctaaag gaaaaatgca aattgcagac ggaatggctt
    60781 caggttcctt gcttttagcg ccggctgacc ctatcgtaga ggactatttg ccaactgata
    60841 aaaaggtggt tcgttttggt caaggagcag agctggaaat tactgacttg gttgagcgca
    60901 aagatagtct gaccttcaag gccaatttct tagagcaagt ccttgatttg ccagtaactg
    60961 gcaagtacaa tgcgacaaat gctatgattg catcctatgt tgccttgcaa gaaggagttt
    61021 cagaggagca aattcgtttg gccttccaac atcttgaatt gacgcgtaac cgtaccgagt
    61081 ggaagaaagc agccaatgga gcagacatct tgtcagatgt ttacaatgcc aatccaactg
    61141 ctatgaagct gattttagag accttctctg ccattccagc caatgaaggt ggcaagaaaa
    61201 ttgcagtgtt ggcggatatg aaggaacttg gtgtccagtc tgttcaactt cataatcaga
    61261 tgattttgag cctttcgcca gatgtgcttg atactgttat tttctacgga gaagatattg
    61321 ctgaattagc ccaacttgct agtcaaatgt tcccaatcgg acacgtttat tacttcaaga
    61381 aaacagaaga ccaagaccaa tttgaagacc tagttaagca ggtcaaagaa agccttgggg
    61441 ctcatgacca aatcctgctc aaaggctcta actctatgaa tctagccaag ttggtagaaa
    61501 gtttagaaaa tgaagacaag tgattttgtc aagtatttgc aaagaatgat tgccattaca
    61561 gatactggat taacctttac aaaagatccg tttgaccgtg agcgctacga agacttgcga
    61621 gaccttctat ctgaaatgtt gaatcaagca tcagaccttg attccgaaga agtggcagaa
    61681 gtcttgaagc caacttctgc ttatgcgact cccttaatgg acgtccgtgc ttggattgtt
    61741 gaggacgaaa agatttgtct ggttagggga caaggagagg atagttgggc tttgccaggt
    61801 ggctttggtg aagtcggcta ttctccaact gaaaatattc tcaaggaaat tgaagaagaa
    61861 accggtttta aagccaaagt tgaaagactg ctagctgttt ttgataccaa tcgtttccaa
    61921 ctacagagca aacaatatgc aaagtttgtt tttgaatgta agcttctcga tggacaattc
    61981 caagaaaatc aagaaatcgc tgaccttcaa ttttttgcaa ttgacccact gccgaattta
    62041 tctgaaaaac gcattaccaa ggagcaaatc gagattcttt ggcaggttta tcaaggtcag
    62101 agggagcaat atcttgacta agaagatgat tatcgtattt ctaaattcat ttttcttaag
    62161 tagcatggta taataaaatg caggaaaatt ttgaatcatg aggaagacta gatgaattta
    62221 tgggatattt tctttacgac tcaggcaacc gagccgccca aatttgacct tttttggtat
    62281 gttagcctat ttacgctctt agccttaacc ttttatacag cccatcgcta tcgtgaaaag
    62341 aaggtttacc aacgattttt ccaaatcttg cagactgttc agttaatcct tctttatggt
    62401 tggtactggg tcaatcatat gccactgtca gaaagcctac ccttttacca ttgccgtatg
    62461 gctatgtttg tggtactctt gcttcctggt cagtccaaat ataaacaata ctttgcatta
    62521 ttgggaacat ttgggacatt agcagccttt gtttatccag tgccagatgc ttaccctttt
    62581 ccacatatca ccattctatc ctttatcttt ggtcatttag cactcttggg gaactctcta
    62641 gtttatctat tgagacagta taatgcgcga ttgctggatg tgaagggaat ttttctcatg
    62701 acctttgccc taaatgcctt gatttttgtg gtcaatttgg tgacaggtgg cgattacgga
    62761 tttttgacaa aaccgccatt ggttggggat cacggtctag tagctaatta tttacttgtt
    62821 tcaattgtgc tggtagctac tatcagtttg actaagaaaa tcttagaatt ctttttagct
    62881 caagaagcag aaaaaatgat tgcaaaggaa gcttaacaca gagctttctt ttttgctctt
    62941 agagagtttt tacaagcagc ttataaaata agaatttctg aatagacaaa ctcaaaaaat
    63001 ggctgggaaa tttaggaaaa aagcaagcac gattaaattt tttgtgttat aatattttgt
    63061 gaatagctat gcctatgttt agctatggaa taatacgaag tgcgaaactt ggaagataga
    63121 gaggaagcga tgtaatggct agagaaggct tttttacagg tctagatatt ggaacaagct
    63181 ctgtcaaggt gcttgtggcc gagcagagaa atggtgaatt aaatgtaatt ggcgtgagta
    63241 atgccaaaag taaaggtgta aaggatggaa ttattgttga tattgatgca gcagcaactg
    63301 ctatcaagtc agccatttcc caagcggaag aaaaggcagg catttcgatt aaatcagtaa
    63361 atgtcggctt gcctggtaat cttttgcagg tagaaccaac tcaggggatg attccagtaa
    63421 catctgatac taaggaaatt acggatcaag atgttgaaaa tgttgtcaaa tcagctttga
    63481 caaagagtat gacacctgac cgtgaagtca ttacctttat tcctgaagaa tttattgtgg
    63541 atggtttcca agggattcgt gacccacgtg gcatgatggg ggttcgcctt gaaatgcgtg
    63601 gtttgcttta tacaggacct cgtactatct tgcacaattt gcgtaagacg gttgagcgtg
    63661 caggtgttca ggttgaaaat attatcattt caccactagc aatggttcag tctgttttga
    63721 atgaagggga acgtgaattt ggtgctacag tgattgatat gggggcaggt caaacgactg
    63781 tcgctacaat ccgtaatcaa gaactccagt tcacacatat tctccaagaa ggtggagatt
    63841 atgtaactaa agatatctcc aaggttttga aaacctctcg caaattagcg gaaggcttga
    63901 aactgaatta cggggaagcc tatccgcctc ttgcaagcaa agaaaccttc caagtagagg
    63961 ttattggaga agtggaagca gtcgaagtga cggaagccta cttgtcagaa attatttctg
    64021 cacgaatcaa gcacatcctt gaacaaatca agcaagaatt agatagaagg cgtctattgg
    64081 acctccctgg tggtattgtc ttaatcggtg ggaatgccat tttaccaggt atggttgagc
    64141 ttgctcagga agtctttggc gtccgtgtca agctttatgt tccaaatcaa gttggtatcc
    64201 gtaatccagc ctttgcgcat gtgattagtt tatcagaatt tgcgggtcaa ttaacagaag
    64261 ttaatctttt ggctcaggga gcgataaaag gtgagaatga cttaagtcat cagccaatta
    64321 gttttggtgg gatgctgcaa aaaacagctc agtttgtaca atcaacgcct gttcaaccag
    64381 ctcctgctcc agaagtagag tcggtggcgc ctacagaacc aatggcggat ttccaacaag
    64441 cttcacaaaa taaaccgaaa ttagcagatc gtttccgtgg cttgatcgga agcatgtttg
    64501 acgaataaag aggaaaaata aattatgaca ttttcatttg atacagctgc tgctcaaggg
    64561 gcagtgatta aagtaattgg tgtcggtgga ggtggtggca atgccatcaa ccgtatggtc
    64621 gacgaaggtg ttacaggcgt agaatttatc gcagcaaaca cagatgtaca agcattgagt
    64681 agtacaaaag ctgagactgt tattcagttg ggacctaaat tgactcgtgg tttgggtgca
    64741 ggaggtcaac ctgaggttgg tcgtaaagcc gctgaagaaa gcgaagaaac actgacggaa
    64801 gctattagtg gtgccgatat ggtcttcatc actgctggta tgggaggagg ctctggaact
    64861 ggagctgctc ctgttattgc tcgtatcgcc aaagatttag gtgcgcttac agttggtgtt
    64921 gtaacacgtc cctttggttt tgaaggaagt aagcgtggac aatttgctgt agaaggaatc
    64981 aatcaacttc gtgagcatgt agacactcta ttgattatct caaacaacaa tttgcttgaa
    65041 attgttgata agaaaacacc gcttttggag gctcttagcg aagcggataa cgttcttcgt
    65101 caaggtgttc aagggattac cgatttgatt accaatccag gattgattaa ccttgacttt
    65161 gccgatgtga aaacggtaat ggcaaacaaa gggaatgctc ttatgggtat tggtatcggt
    65221 agtggagaag aacgtgtggt agaagcggca cgtaaggcaa tctattcacc acttcttgaa
    65281 acaactattg acggtgctga ggatgttatc gtcaacgtta ctggtggtct tgacttaacc
    65341 ttgattgagg cagaagaggc ttcacaaatt gtgaaccagg cagcaggtca aggagtgaac
    65401 atctggctcg gtacttcaat tgatgaaagt atgcgtgatg aaattcgtgt aacagttgtt
    65461 gcaacgggtg ttcgtcaaga ccgcgtagaa aaggttgtgg ctccacaagc tagatctgct
    65521 actaactacc gtgagacagt gaaaccagct cattcacatg gctttgatcg tcattttgat
    65581 atggcagaaa cagttgaatt gccaaaacaa aatccacgtc gtttggaacc aactcaggca
    65641 tctgcttttg gtgattggga tcttcgccgt gaatcgattg ttcgtacaac agattcagtc
    65701 gtttctccag tcgagcgctt tgaagcccca atttcacaag atgaagatga attggataca
    65761 cctccatttt tcaaaaatcg ttaagtaaat gaatgtaaaa gaaaatacag aacttgtttt
    65821 tcgagaagtt gcagaggcta gtctgagtgc tcatcgagag agtggttcgg tctctgtcat
    65881 tgcagttacc aagtatgtag atgtaccgac agcggaagcc ttgcttccgc taggtgttca
    65941 tcatatcggt gaaaatcgtg tagataagtt tctggaaaaa tatgaagctt taaaagatcg
    66001 agatgtgact tggcatttga ttggtacctt gcaaagacgt aaggtgaaag atgtcattca
    66061 atacgttgat tatttccatg cattggactc agtaaagcta gcaggggaaa ttcaaaaaag
    66121 aagtgaccga gtcatcaagt gtttccttca agtaaatatt tctaaagaag aaagcaaaca
    66181 cggtttttcg agagaggaac tgctggaaat cttgccagag ttagccagac tagataagat
    66241 tgaatatgtt ggtttaatga cgatggcacc ttttgaggct agcagtgagc agttgaaaga
    66301 gattttcaag gcgacccaag atttacaaag agaaattcaa gagaaacaaa ttccaaatat
    66361 gcctatgacc gagttaagta tgggaatgag tcgtgattat aaagaagcga ttcaattcgg
    66421 ttccactttt gttcgtatag gtacatcatt ttttaagtag gagagaacca tgtctttaaa
    66481 agatagattc gatagattta tagattattt tacggaggat gaggattcaa gtctccctta
    66541 tgaaaaaaga gatgagcctg tgtttactcc agtaaattct tcacaggaac cggctctccc
    66601 aatgaatcaa ccttcacagt cggctggtac aaaagagaac aatatcacca gacttcatgc
    66661 aagacaacag gaattggcaa atcagagtca gcgtgcaacg gataaggtca ttatagatgt
    66721 tcgttatcct agaaaatatg aggatgcaac agaaattgtt gatttattgg caggaaacga
    66781 aagtatcttg attgattttc agtatatgac agaggtgcag gctcgtcgtt gtttggacta
    66841 tttggatgga gcttgtcatg ttttagctgg aaatttgaaa aaggtagctt ctaccatgta
    66901 tttgttgaca ccagtgaatg ttattgtaaa tgttgaagat atccgtttac cagatgaaga
    66961 tcaacagggt gagttcggtt ttgatatgaa gcgaaataga gtacgataat gattttttta
    67021 attcgtatga tttataatgc agtggatatt tactccctga ttttggtagc cttcgctgtc
    67081 atgtcttggt ttccaggtgc ctacgaatcc agtttaggtc gttggattgt agcgttggtg
    67141 aaaccagtgc ttgctccctt gcaacgcctg cctttacaga tagcgggtct tgatttatct
    67201 gtttgggtcg cgattgtttt ggttcgattt ttaggagaaa acctagtgcg ttttctggcg
    67261 atgataggat gaataaaggg atttatcagc atttctccat agaagatcgt ccatttcttg
    67321 acaagggaat ggaatggata aagaaggtag aagatagcta tgctcctttt ttaactcctt
    67381 ttatcaatcc tcatcaggag aagctattaa agattttggc caaaacctat ggtcttgctt
    67441 gtagcagtag tggggaattc gtctcgagtg agtatgttcg agttttatta tacccagatt
    67501 atttccaacc agagttttca gattttgaaa tatctctcca ggaaattgtg tattccaata
    67561 aatttgaaca tttaacgcat gctaagattt tagggacagt catcaatcaa ttagggattg
    67621 aacggaaact ttttggagat atcctagtag atgaagaacg ggcgcagatt atgattaatc
    67681 agcagtttct tcttctcttt caagatggac taaagaaaat tggtcgtata cctgtttcgc
    67741 tggaggaacg tcctttcacc gagaaaatag ataagctaga acagtatcga gaactggatt
    67801 tatctgtgtc tagttttcga ttagatgttc tttgttcaag ttggagactt gattagtgtg
    67861 agaaaatttg gtcgcttgag attacttcaa gataagggac aaacgaaaaa agagaagaaa
    67921 aaaataaccg tccagttatt attaagtaag tgaggaatag aatgccaatt acatcattag
    67981 aaataaagga caagactttt ggaactcgat tcagaggttt tgatccagaa gaagtcgatg
    68041 aatttttaga tattgtggtt cgtgattacg aagatcttgt gcgtgcgaat catgataaaa
    68101 atttgcgtat taagagttta gaagagcgtt tgtcttactt tgatgaaata aaagattcat
    68161 tgagccagtc tgtattgatt gctcaggata cagctgagag agtgaaacag gcggcgcatg
    68221 aacgttcaaa caatatcatt catcaagcag agcaagatgc gcaacgcttg ttggaagaag
    68281 ctaaatataa ggcaaacgag attcttcgtc aagcaactga taatgctaag aaagtcgctg
    68341 ttgaaacaga agaattgaag aacaagagcc gtgtcttcca ccaacgtctc aaatctacaa
    68401 ttgagagtca gttggctatt gttgaatctt cagattggga agatattctc cgtccaacag
    68461 ctacttatct tcaaaccagt gatgaagcct ttaaagaagt ggttagcgaa gtacttggag
    68521 aaccgattcc agctccaatt gaagaagaac caattgatat gacacgtcag ttctctcaag
    68581 cagaaatgga agaattacaa gctcgtattg aggtagccga taaagaattg tctgaatttg
    68641 aagctcagat taaacaggaa gtggaaactc caactcctgt agtgagtcct caagttgaag
    68701 aagagcctct gctcatccag ttggcccaat gtatgaagaa ccagaagtag ctccagtgca
    68761 tccgacaggt ccaacaccag ctacagaaac tgttgattca gcaccgggat ttgaagcacc
    68821 gcaagaatct gttacaattt tataagaaat attctgagaa caatatctta tccttatatt
    68881 cccagcgagc aggagatggt gtgagtcctg cattccctat cgataagatt atcctctcaa
    68941 actatcaagt ctgaatctag taagatttga cgttccccac gttacgggat aagagggaga
    69001 aagactaaaa ctttttccga ataaaggtgg taccacgatt ttcgtccttt ttggaagtcg
    69061 tggtttttaa tttgttatta tttataaagg agataccatg aaactcaaag acacccttaa
    69121 tcttgggaaa actgaattcc caatgcgtgc aggccttcct accaaagagc cagtttggca
    69181 aaaggaatgg gaagatgcaa aactttatca acgtcgtcaa gaattgaacc aaggaaaacc
    69241 tcatttcacc ttgcatgatg gccctccata cgctaacgga aatatccacg ttggacatgc
    69301 tatgaacaag atttcaaaag atatcattgt tcgttctaag tctatgtcag gattttacgc
    69361 accatttatt cctggttggg atactcatgg tctgccaatc gagcaagtct tgtcaaaaca
    69421 aggtgtcaaa cgtaaagaaa tggacttggt tgagtacttg aaactttgcc gtgagtacgc
    69481 tctttctcaa gtagataaac aacgtgaaga ttttaaacgt ttgggtgttt ctggtgactg
    69541 ggaaaatcca tatgtgacct tgactcctga ctatgaagca gctcaaattc gtgtatttgg
    69601 tgagatggct aataagggtt atatctaccg tggtgctaag ccagtttact ggtcatggtc
    69661 atctgagtca gcccttgctg aagcagagat tgaataccat gacttggttt caacttccct
    69721 ttactatgcc aacaaggtaa aagatggcaa aggagttcta gatacagata cttatatcgt
    69781 tgtctggaca acgactccat ttactatcac agcctctcgt ggtttgacgg ttggtgcaga
    69841 tattgattac gttttggttc aacctgctgg tgaagctcgt aagtttgtcg ttgctgctga
    69901 attattgact agcttgtctg agaaatttgg ctgggctgat gttcaagttt tggaaactta
    69961 ccgtggccaa gaactcaacc acatcgtaac agaacaccca tgggatacag ctgtagaaga
    70021 gttggtaatt cttggtgacc acgttacgac tgactctggt acaggtattg tccatacagc
    70081 ccctggtttt ggtgaggacg attacaatgt tggtattgct aataatcttg aagtcgcagt
    70141 gactgttgat gaacgtggta tcatgatgaa gaatgctggt cctgaatttg aaggtcaatt
    70201 ctatgaaaag gtagttccaa ctgttattga aaaacttggt aacctccttc ttgcccaaga
    70261 agaaatctct cactcatatc catttgactg gcgtactaag aaaccaatca tctggcgtgc
    70321 agttccacaa tggtttgcct cagtttctaa attccgtcaa gaaatcttgg acgaaattga
    70381 aaaagtgaaa ttccactcag aatggggtaa agtccgtctt tacaatatga tccgtgaccg
    70441 tggtgactgg gttatctctc gtcaacgtgc ttggggtgtt ccacttccta tcttctacgc
    70501 tgaagatggt acagctatca tggtagctga aactattgaa cacgtagctc aactttttga
    70561 agaacatggt tcaagcattt ggtgggaacg tgatgccaaa gacctcttgc cagaaggatt
    70621 tactcatcca ggttcaccaa acggcgagtt caaaaaagaa actgatatca tggacgtttg
    70681 gtttgactca ggttcatcat ggaatggagt ggtggtaaac cgtcctgaat tgacttaccc
    70741 agccgacctt tacctagaag gttctgacca ataccgtggt tggtttaact catcacttat
    70801 cacatctgtt gccaaccatg gcgtagcacc ttacaaacaa atcttgtcac aaggttttgc
    70861 ccttgatggt aaaggtgaga agatgtctaa atctcttgga aataccattg ctccaagcga
    70921 tgttgaaaaa caattcggtg ctgaaatctt gcgtctctgg gtaacaagtg ttgactcaag
    70981 caatgacgtg cgtatctcta tggatatctt gagccaagtt tctgaaactt accgtaagat
    71041 tcgtaacact cttcgtttct tgattgccaa tacatctgac tttaacccag ctcaagatac
    71101 agtcgcttac gatgagcttc gttcagttga taagtacatg acgattcgct ttaaccagct
    71161 tgtcaagacc attcgtgatg cttacgcaaa ctttgaattc ttgacaatct acaaggcctt
    71221 ggtgaacttt atcaacgttg acttgtcagc cttctacctt gattttgcca aagatgttgt
    71281 ttacattgaa ggtgccaaat cactggaacg ccgtcaaatg cagactgtct tctatgacat
    71341 tcttgtcaaa atcaccaaac tcttgactcc aatccttcct cacactgcgg aagaaatctg
    71401 gtcatatctt gagtttgaag ccgaagactt cgtccaattg tcagaattac cagaagttca
    71461 aacttttgct aaccaagaag aaatcttgga tacatgggca gccttcatgg acttccgtgg
    71521 acaagcacaa aaagccttgg aagaagctcg taatgcaaaa gttatcggta aatcacttga
    71581 agcacacttg acagtttatc caaatgaagt tgtgaaaact ctactcgaag cagtaaacag
    71641 caatgtagct caacttttga tcgtgtctga gttgaccatc gcagaagaac cagctccgga
    71701 agctgccctt agcttcgaag atgtagtctt cacagttgaa cgcgctgcag gtgaagtatg
    71761 tgaccgttgc cgtcgtattg acccaacaac agcagaacgt agctaccacg cagtcatctg
    71821 tgaccactgt gcaagtatcg tagaagaaaa ctttgcagat gcagtcgcag aaggatttga
    71881 agagaaataa gattgaaaag tctaggtaaa actcaatttg agaagaaaag acaactaatt
    71941 ttatagtcta ttaaacgcat tgtatcacgt ttttgaacac ctgatatgat gcgtttttta
    72001 tttattttaa aaatttgcga ggtatgactt tttatactca acaagaatca aagagaaact
    72061 tagcaagcta acagtagtaa tataaaatag gaatttgata ttagggataa gattggtaaa
    72121 tagtgtaata tttttacaac aataaattta tatagttatt tctggtttct gaaaagtatt
    72181 atattatatt ttatttcata ttatacaaat ttttatttta taatatcaga aaatactttt
    72241 tttaaaaagc aaatatgata caattttatt tgaaaaaaaa taaaaaagga gattttatta
    72301 tgaaatcaag tggtatcgtc ggtcttgtgg gaggaatttt acttcttatt tgtccttttg
    72361 tcttgttggg aacagcggta aatacagctg ctacaactct taatggagga gctactgcag
    72421 gggctttttc aggtgttgcc ttactcttga atgccttgaa gattgcaaat cttgttcttg
    72481 gtatcattgc tattgtttac tataaaggag ataagcatgt aggtgcagct ccgtctgtac
    72541 taatgattgt ttctggtgaa gttagtctca ttccattctt aggatgggtt ggggggattc
    72601 ttgctattat cggaggatct ctattccttg caacattgaa gaaattcaaa tcagaagaat
    72661 aaaaggtatt ttagcatgaa aagaacaaaa aagtttatcg gtataggagt agctctatta
    72721 tctctttctc ttctagttgc atgtggaaca taaagttcaa agaatacttc aacaagtaat
    72781 gatgagaaga cagtagcaac atccaatagt tcaaaagaaa caatcacttt cgatacaccg
    72841 gttgtaacag acgatgcgat tgaatcaata cgcacttatg cagattatat agatctttat
    72901 aaaaatattt ttgatgatta ttttactaaa gctgaggaag gtttcaaagg cacaactatg
    72961 gaaaataatg actcgtttac taaactaaaa gagtcaactc aaaaattatt cgatgcgcag
    73021 aaaaaaaggt taaataatga agatagaata gaaacaacca aaaacaatgt gattgccaaa
    73081 cattgtcaaa cagtcctttc ctttttggtt ttgactagct tttttgtgaa aaattgtgta
    73141 aaatagaata gataaacgag gggaaacctc ggaaaattta aaggagaatc catctaatgg
    73201 taaaattggt ttttgctcgc cacggtgagt ctgaatggaa caaagctaac cttttcactg
    73261 gttgggctga tgttgatttg tctgaaaaag gtacacaaca agcgattgac gctggtaaat
    73321 tgatcaaaga agctggtatc gaatttgacc aagcttacac ttcagtattg aaacgtgcta
    73381 tcaaaacaac taacttggct cttgaagctt ctgaccaatt gtgggttcca gttgaaaaat
    73441 catggcgctt gaacgaacgt cactacggtg gtttgactgg taaaaacaaa gctgaagctg
    73501 ctgaacaatt tggtgatgag caagttcaca tctggcgtcg ttcatacgat gtattgcctc
    73561 caaatatgga ccgtgatgat gagcactcag ctcacacaga ccgtcgttat gcttcacttg
    73621 acgactcagt cattccagat gctgaaaact tgaaagtgac tttggaacgt gctcttccat
    73681 tctgggaaga taaaatcgct ccagctctta aagatggtaa aaacgtattc gtaggagctc
    73741 acggtaactc aatccgtgcc cttgtaaaac acatcaaagg tttgtcagat gatgagatca
    73801 tggacgtgga aatccctaac ttcccaccat tggtattcga attcgacgaa aaattgaacg
    73861 ttgtttctga atactacctt ggaaaataaa aaattgtaag cctaggattg atttctaggc
    73921 tttttatgtt agtatggaag tatgataagg aataaaaaac aagattatgt actggcctac
    73981 aagcaaccag cttcaaccac ttacatgggt tgggaagaag aagctttacc gataggcaat
    74041 ggttctttag gagcaaaagt atttggcctt ataggggctg aacggattca atttaatgaa
    74101 aaaagtctct ggtctggagg tccacttcct gatagttcag attatcaggg tggaaatctt
    74161 caggatcagt atgttttttt agctgagatt cggcaggctt tggagaagag agattacaat
    74221 ctggctaagg aactggctga gcagcaccta attgggccaa aaacgagtca atatgggacc
    74281 tatctgtctt ttggggatat tcacattgag ttcagccagc aaggtacgac tttgtctcag
    74341 gtgacggact atcagagaca gctgaatatt agtaaggcac ttgcgacgac ttcttatgtc
    74401 tataagggaa cgcgatttga acgtaaagct tttgcgagtt ttccagatga tctcttgatt
    74461 caatgtttta ctaaggaagg gttggaaact ctagatttta ctatagaact atccttgacc
    74521 tgtgatttgg cttctgatgg aaagtatgag caggaaaaat ctgattacaa ggagtgtaag
    74581 ttggatatta ctgattctca tatcttgatg aagggaagag ttaaggataa tgatctgcgg
    74641 tttgctagtt atctagcttg ggaaacggat ggagatatta gagtttggtc agatagggtt
    74701 cagatatcag gagccagtta tgccaatctc ttcttggccg ctaagacgga ttttgcccaa
    74761 aatcctgcta gcaattatcg caagaaacta gatttagagc aacaggtgat agacttggtg
    74821 gacacagcta aagaaaaggg ctatacccaa ttgaaatcaa ggcatatcga ggactaccaa
    74881 gccttattcc agcgtgttca attggatttg gaagctgatg ttgacgcatc cactacagat
    74941 gatttgttaa aaaattataa gccacaagaa gggcaggctt tggaggagct gttcttccag
    75001 tatggacggt atttattgat tagttcgtcc agagactgcc cagatgctct accagctaac
    75061 ctacagggag tctggaatgc ggtcgacaat cctccttgga attcggacta tcacttaaat
    75121 gtcaatctgc agatgaatta ttggccagcc tatgttacca atctcctaga gacggtcttt
    75181 ccagtcatca actatgtaga tgatttgcgt gtctatggtc gtctagcggc tgtaaagtat
    75241 gcaggaatcg tctctcaaaa aggtgaggaa aatggttggt tggttcatac tcaagcgact
    75301 ccctttggtt ggacggcacc tggttgggat tactattggg gttggtcacc agctgccaat
    75361 gcgtggatga tgcaaaccgt ttatgaagcc tattcatttt atagggacca agactatctc
    75421 agggagaaaa tttatcccat gttgagggaa acggttcgtt tttggaatgc ctttttacat
    75481 aaggatcagc aggcgcagcg ttgggtctct tctccgtctt attccccaga acatgggccg
    75541 atttcgattg gcaataccta tgaccaatct ctgatttggc agttatttca tgattttatt
    75601 caggctgctc aggaattggg actggatgag gacttgttga ctgaggttaa ggagaagtct
    75661 gatttactaa atcctttgca aatcactcaa tctggtcgaa tcagggagtg gtatgaggag
    75721 gaagagcagt attttcaaaa tgagaaagtg gaggcccagc atcggcacgc ttcccatcta
    75781 gtgggactct attctggcaa tctctttagc tacaagggac aagagtatat tgaagcggcg
    75841 cgtgctatcc tcaatgatcg tggagatggc ggcacaggct ggtccaaggc taataagatc
    75901 aatctctggg cgcgtttggg agatggcaat cgagcccata aattattggc agagcagtta
    75961 aagacatcca ccttgccaaa tctttggtgt agccatcctc cttttcagat agatggtaat
    76021 tttggtgcta ctagtggcat ggcagaaatg ttactccagt ctcatgcagc ttatctggta
    76081 cctctagctg ccctacctga tgcttggtca acaggttctg tttcaggctt aatggcacgt
    76141 ggacattttg aagtgagcat gagctgggaa gataaaaaac tcttacagtt gaccatttta
    76201 tcaaggagtg gaggagattt gcgagtttct tatccagata ttgagaagag tgtgattaaa
    76261 atgaatcaag aaaaaataaa agcgaaatgc atggggaaag attgtatttc ggtggcaaca
    76321 gcagaaggtg atcttgttca attttatttt taagaagatg ttataaggca gtaatttgaa
    76381 acttcctttt aataaggatt tgagaatata ggcagtttcc aactagttga aaaagcgtta
    76441 taatgataat aggaagtaat actcaatgaa aatcaaagag cacaaactag gaagctagcc
    76501 gcaggttgct caaaacagtg ttttgaggtt gtagatggaa gctgacgtgg tttgaagaga
    76561 gattttcgag gagtataatt tgtttgatag agggtgggtc tgatggctta tattgagatg
    76621 aaacactgtt acaagcgtta tcaggttggg gacacggaga ttgtggccaa tcgtgatgtg
    76681 aattttgaga ttgaaaaggg ggagctggtt attatccttg gtgcttcagg tgcaggcaag
    76741 tcaacagttc ttaaccttct tgggggaatg gataccaatg atgaagggga aatctggatt
    76801 gatggtgtta atattgcgga ttatagttcc caccagcgta ccaattaccg tagaaatgat
    76861 gtggggtttg tttttcagtt ttataatcta gtttctaatc tgacagctaa ggaaaatgtg
    76921 gaactggctt ctgaaattgt gacagatgcc ttgaatcctg atcaggtctt gacagatgta
    76981 ggtctggctc atcgtctcaa taactttcca gcccagcttt ctggagggga gcaacagcga
    77041 gtctccattg cacgcgcggt agccaaaaat cctaaaattc tcctttgtga tgaaccgact
    77101 ggagccttgg attatcagac gggcaagcag gttttgaaaa ttctccaaga catgtctcgt
    77161 caaaagggag cgacggtgat catcgtgact cataatggag ctttggcgcc cattgctgat
    77221 cgcgtgattc aaatgcacga tgccagtgtc aaggatgtgg tgctcaacca gcatcctcag
    77281 gatattgaca gtttggagta ctagcatgat caagcgaaaa acttattgga aggacttaat
    77341 tcagtccttc acaggctcca aggggcgttt tttatccatc ttgatcctga tgatgttggg
    77401 atctctagcc ttagtaggcc tcaaagtaac cagtcccaac atggaggcga cagctaatgc
    77461 ttatttaaca actgctcaaa ccttggattt ggcagtcatg tctaactatg gcttggatca
    77521 agcagaccaa gaagaactaa aacagacgga gggcgcagag gtcgagtttg gctatttgac
    77581 agatgtgact atggataatg ggcaggatgc cattcggctg tactccaaac cagagcgaat
    77641 ttcaaccttt cagctaagaa agggacgact tcctcagtca gacaaggaaa tcgctttggc
    77701 cactcatttg caaggccaat acagcgtggg acaggagatt agttttaaag aaaaagaaga
    77761 gggtcattcc tctttaaaag accatactta taccattact ggttttgtgg attcggctga
    77821 aatcctctcc cagcgagata tgggctacgc aggaagtgga agtgggactc tgacagccta
    77881 tggggtgatt ttacctagtc agtttgatca gaaagtctac aatatagctc gtttgaaata
    77941 tcaagattta gcaggtttaa atgccttttc atcagcttat gaagaaaaat ccaagcaaca
    78001 tcaggaagac cttgaacaaa ctttatcaga taatggcaag gtacgtctgc aacttttgaa
    78061 aaaagaagga caagagtctc tagacaaggg gcaagagacc cttgacaagg ctcagactaa
    78121 tttgcaggaa ggcaagcgtc gtttagcagc tgctcaagct cgtatacagg ctcaagaaag
    78181 tcaactagcc ttgtttcctc aagttcagag agagcaggct agtgctcaac ttacccaagc
    78241 caagcaggaa ttgggcaagg aagaggataa actaaagcaa gctgaacaaa atctagccca
    78301 agaaaaggaa aaattagaaa aacatcagca agtcttggac gatttggcgg agccaaggta
    78361 tcaggtctat aatcgtcaga ccatgccagg tggtcagggc tatcttatgt atagcaatgc
    78421 ttcatccagt attcgagcag tgggcaatat ctttcctgtg gtactttatg ccgtagcatc
    78481 catggtgacc tttacgacca tgactcgctt tgtagacgaa gagcgaactc atgcagggat
    78541 ttttaaggcc ttgggttacc gtagtaagga tattatcacc aagtttctcc tttatggact
    78601 agtagctggg actgtcggaa cggctctagg tagtatactt ggtcattatt tgctagccag
    78661 tgtaatttca agtgtcatta caaaaggcat ggtggtggga gaaacccaga ttcagttcta
    78721 ttggacctat agcttactag ctcttgtctt gagctggttg gcgagtgtgt taccagccta
    78781 tctggtggct tggagggaac ttcatgccga agcagcccag cttctacttc ctaaacctcc
    78841 tgtcaaagga gctaaaatct tattggagcg tatcggtttt atctggcgtc gtctcagttt
    78901 tactcataag gtaacagccc gcaacatctt tcgttataag cagagaatgt tgatgacaat
    78961 ctttggtgtg gcaggttctg tagctctgct ctttgcaggt ttgggaatcc aatcttctgt
    79021 agcaggagtt ccgtctaaac agtttcaaca aatccaacag tatcagatgc ttgtctctga
    79081 aaatcctagt gcgaccaatc aggacaaggt agagctagca gaagtgttga aagggcagga
    79141 gatactagcc taccagaaaa tctattctaa aacgctagac aaggatttca aaggcaaggc
    79201 tggtcttcaa aacattactc ttatgatgat agagaaggaa gatttgactc cctttatcca
    79261 tcttcaacat catcagcagg agctgacatt aaaagatggc atcgttatta cagctaaact
    79321 cgcccagctg gcaggtgtca aggttgggca gactttagaa attgaaggta aggaactaaa
    79381 ggtcgctgct attactgaga actacgttgg tcactttatt tatatgagtc aggctagcta
    79441 tgagcaactt tacggacagc taccccaagc caacacttat ctggtctcat taagggatac
    79501 cagtgcaact agtatcgaaa gtcaggcggg cttgcttatg aatcaatctg cggtgtccag
    79561 cgttgtccaa aatgcttcag ccattcgact ctatcgctag ctcactcaat cagaccatga
    79621 ccatcttggt catcgtatca gttctattag ctattgtcat cctttacaat ctgaccaata
    79681 tcaacgtagc tgagagaatc cgtgaactct ccactatcaa ggttctcggt tttcataata
    79741 atgaagtcac cctctacatt taccgtgaga cgattgtgct gtcccttgtg ggaatcgtac
    79801 ttggtctggt agctggtttc tatttacacc aatttttgat tcaaatgatt tcgcctgcga
    79861 ctattctctt ttatccgcag gtaggctggg aagtctatgt aatcccagtg gcaacagtaa
    79921 gcatcatttt gaccttgctt ggtttcttcg tcaattatta tctgagaaag gttgatatgt
    79981 tagaagccct gaaatctgta gagtaaggta gttattttta gctgattgaa cttctattta
    80041 ctaatattca aaaatcctct gtcacaaaga gcagggagct ctttgtgaca gaggattttt
    80101 tctatagggc tttagcagct gcaattgcgg cttcgaagtt tggctcagaa ttgatattat
    80161 ccacgtattc aacgtagcga atcgtattgt cagtatcgag gacaaagact gcgcgtgcta
    80221 ataggtgcca ttcgttgatc aagagggcat aatcgcgccc gaaagaatgg tcaaagtagt
    80281 ctgaaagcat aatggcattg tcaaggcctt cagcaccgca ccaacgtttt tgagcaaaag
    80341 gtaggtccat tgaaacagtc aatacgaccg tgttgtccag tccagccaat tcttcattaa
    80401 aacgacgtgt ttgagttgag cagatgcctg tatcgataga aggaacgaca ctcaagactt
    80461 ttttcttgcc atcaaaatca gccagagatt ttttagaaag atctgttgta gtaagagaaa
    80521 aatcaagcgc cttgtcgccg acttgtagtt gtttacctgt aaagctcaca ggatttccga
    80581 gaaaagttac cataggatac tccaatcttt tttcttccat tgtatctgaa acagtcagaa
    80641 ttttccaatg atttgaccgg aaatgtgggc atagaaaaaa cgccagctca catgagaatg
    80701 acgtttttca gaggcttatt ttgccaatcc ttcagcaatc ttgtcaaggt tgtatttcat
    80761 catgctgtag tagctgtcgc cttctttacc ttgttctgcg atagagtcag taaagatttg
    80821 tgcgtagatt gggatgtttg tgtcttgaga aacagttttc attggacggt catccacact
    80881 tgattctaca aagagtgatg gaacttttgt ttggcgaagt ttttcaacca aggtcttgat
    80941 ttgttcagga gttccttctt cttcagtatt gatttcccag atgtaagcac ttgggacacc
    81001 ataggcttta gagaagtatt tgaatgctcc ttcgctggtt acaatgagtt tcttttcagc
    81061 agggatctta ttaaatttat ccttactttc tttatcaagt ttgtctaact tatcagtata
    81121 ttctttgaga tttttttcat agaattcttt attgttaggg tctttggcgc tcaattgttt
    81181 ggcgatattt ttagcaaaaa taataccgtt ttcaaggtta agccaagcgt gtgggtcttc
    81241 ttttcctttt tcattttgac cttcaaggta gataacatca acgccgtcgc tgactgcgaa
    81301 gtagtctttg ttttcagttt tcttggcatt ttctaccaat tttgtaaacc aagcattgcc
    81361 acctgtttca aggttgatac cgttatagaa aatcaaatca gcctcagaag ttttcttaac
    81421 gtcttcagga agtggttcgt attcgtgtgg gtcttgccca atcggaacga tactatgaag
    81481 gtcaattttg tcaccagcaa tatttttagt aatatcagcg atgattgagt ttgtagcaac
    81541 aacttttagt ttttgaccag aagttgtatc tttttttccg ctagcacatg ctacaagaat
    81601 gattgcagaa agaaagagaa cgagtaatgt acctaatttt ttcattagat cctccaaatt
    81661 attagggctt tgccccttat tttaacaaat gtttattttt cagtttcaaa tatcgttgtt
    81721 tgggagcgat aaagaagcta atgagaaaga aactagcagc tgtaagcacg atactagaac
    81781 ctgccgcaac attaaaacta tagccaataa agagtcccaa aactgaagca gtagctccga
    81841 aggttgagga aaggaaaatc atgcttttca gactattagc atacagataa gcagttgcag
    81901 ctggggtaat cagcatggct acaatcagga tagttccgac actttgcatg gctgtcacag
    81961 acacgagagt caggagtacc atgagaaggt agtgatagaa attgacaggc attcccatgg
    82021 ctttagccaa gagttcatca aaggaagtta tcaagagttg cttgaagaaa atccagatta
    82081 acaagaggat ggctgccccc acacccatag taataaacat atccgtatct tggacggcca
    82141 ggatattacc aaaaaggata tggaaaaggt cagttgaact tttagcgaca ccaatcaaga
    82201 tgataccgag ggctaagaaa gaagaaaagg taatgccgat ggcggtatcg cttttgataa
    82261 tcgagtttcc tttgatgtag gtaatgatga tggcagctag caatccaaag acaatggctc
    82321 cgataaagaa gtcaaggccc aagatgaagg agagggctac acctggtaag acagcatgtg
    82381 aaatggcatc tcccatgagt gacatcccgc gtagaataat gaaacatccc acagctccag
    82441 ctacaatccc gacgacaata gctgttatca aggcattttg taggaaatgg aatttttgca
    82501 atccatcgat aaattctgca atcataggtc acctccattg aaaaagagtt gattaccgta
    82561 agcttctttt agattggttt cggtaaaagt ttcttttgtt ggaccaaagg caatcacttc
    82621 tcgattgaca agtaagactt gatcgaagta gtggggaatc ttgctgaggt cgtggtgaac
    82681 gatgagaacc gtcttcccag cttttttcaa atctctcagc gtattcatga tgatttcctc
    82741 actgacagag tcaatcccag caaagggttc atccaagagg atatagtcgg cttcctgcac
    82801 caaacatctg gcaatcaaaa cccgctggaa ttgacctcca gacagttgac taatttgacg
    82861 ttcagcgtag tcagctaggc cgacgatttc aagggcctct tgcactttct tccaatgttt
    82921 agcctttaaa cttcgaaaga gaggaataga gggaaatagt cctaacgaga cgcattcctt
    82981 gaccttgatg ggaaagttgt agtcgatatt gattttttgt tcgacatagg caattcggtg
    83041 taaggatttt ttaacttcct tgtcatcgag aaatgcctga ccttgatgtg ggataattcc
    83101 cagcatacct tttaatagtg ttgatttccc agcgccgttt ggaccaatga tgccggtaat
    83161 tgttggtcca tggagcacta gtgaaatatc cttaagtgcc aacgtttctt tgtaggagac
    83221 actgaggttt tcgatacgta tcataaactt gtattcctcc tgtctcttaa tatacattaa
    83281 aaaaaaaatt aagtcaagtt aatttttgaa aaaattaaaa taataactga aaaataga
//
LOCUS       DAVBEM010000004        67315 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVBEM010000004 DAVBEM010000000
VERSION     DAVBEM010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67315
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.004"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(134..1882)
                     /locus_tag="VQ548_000264"
     CDS             complement(134..1882)
                     /locus_tag="VQ548_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2653189.1"
                     /translation="MKRQTVNQTLKRLVVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKELSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTISRVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(1884..3608)
                     /locus_tag="VQ548_000265"
     CDS             complement(1884..3608)
                     /locus_tag="VQ548_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2653190.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENLPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(3666..4604)
                     /gene="msrB"
                     /locus_tag="VQ548_000266"
     CDS             complement(3666..4604)
                     /gene="msrB"
                     /locus_tag="VQ548_000266"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET2653191.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(4746..4823)
                     /locus_tag="VQ548_000267"
                     /pseudo
     CDS             complement(4746..4823)
                     /locus_tag="VQ548_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4899..5768)
                     /locus_tag="VQ548_000268"
     CDS             complement(4899..5768)
                     /locus_tag="VQ548_000268"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HET2653192.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTKGVRVEAK"
     gene            complement(5770..7056)
                     /locus_tag="VQ548_000269"
     CDS             complement(5770..7056)
                     /locus_tag="VQ548_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HET2653193.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(7207..7944)
                     /gene="mecA"
                     /locus_tag="VQ548_000270"
     CDS             complement(7207..7944)
                     /gene="mecA"
                     /locus_tag="VQ548_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HET2653194.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(8144..9178)
                     /locus_tag="VQ548_000271"
     CDS             complement(8144..9178)
                     /locus_tag="VQ548_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET2653195.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(9207..10640)
                     /locus_tag="VQ548_000272"
     CDS             complement(9207..10640)
                     /locus_tag="VQ548_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HET2653196.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFIAKMLTKEN"
     gene            complement(10656..11642)
                     /locus_tag="VQ548_000273"
     CDS             complement(10656..11642)
                     /locus_tag="VQ548_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2653197.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQIYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(11644..12747)
                     /locus_tag="VQ548_000274"
     CDS             complement(11644..12747)
                     /locus_tag="VQ548_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET2653198.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDLEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQIIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(12737..13582)
                     /locus_tag="VQ548_000275"
     CDS             complement(12737..13582)
                     /locus_tag="VQ548_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2653199.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLTLDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(13861..15135)
                     /gene="psr"
                     /locus_tag="VQ548_000276"
     CDS             complement(13861..15135)
                     /gene="psr"
                     /locus_tag="VQ548_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HET2653200.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(15132..15980)
                     /gene="pheA"
                     /locus_tag="VQ548_000277"
     CDS             complement(15132..15980)
                     /gene="pheA"
                     /locus_tag="VQ548_000277"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET2653201.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYIDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(15977..16453)
                     /locus_tag="VQ548_000278"
     CDS             complement(15977..16453)
                     /locus_tag="VQ548_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HET2653202.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRHVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(16446..17729)
                     /gene="aroA"
                     /locus_tag="VQ548_000279"
     CDS             complement(16446..17729)
                     /gene="aroA"
                     /locus_tag="VQ548_000279"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HET2653203.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(17821..18159)
                     /locus_tag="VQ548_000280"
     CDS             complement(17821..18159)
                     /locus_tag="VQ548_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HET2653204.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(18170..19273)
                     /locus_tag="VQ548_000281"
     CDS             complement(18170..19273)
                     /locus_tag="VQ548_000281"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HET2653205.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(19283..20449)
                     /gene="aroC"
                     /locus_tag="VQ548_000282"
     CDS             complement(19283..20449)
                     /gene="aroC"
                     /locus_tag="VQ548_000282"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HET2653206.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(20459..21526)
                     /locus_tag="VQ548_000283"
     CDS             complement(20459..21526)
                     /locus_tag="VQ548_000283"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HET2653207.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(21545..22399)
                     /locus_tag="VQ548_000284"
     CDS             complement(21545..22399)
                     /locus_tag="VQ548_000284"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HET2653208.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKKMPTEEIW
                     QSLTEKYQ"
     gene            complement(22389..23066)
                     /locus_tag="VQ548_000285"
     CDS             complement(22389..23066)
                     /locus_tag="VQ548_000285"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HET2653209.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(23063..24226)
                     /locus_tag="VQ548_000286"
     CDS             complement(23063..24226)
                     /locus_tag="VQ548_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HET2653210.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDERRFIVMDVFEYF
                     KYAKRKNLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(24911..26545)
                     /locus_tag="VQ548_000287"
                     /pseudo
     CDS             complement(24911..26545)
                     /locus_tag="VQ548_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(26526..27275)
                     /locus_tag="VQ548_000288"
     CDS             complement(26526..27275)
                     /locus_tag="VQ548_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2653211.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSAPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVEN
                     LRKDHPDQFLESIYLSLAGRKEEVADASQGH"
     gene            27454..28908
                     /locus_tag="VQ548_000289"
     CDS             27454..28908
                     /locus_tag="VQ548_000289"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HET2653212.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKEQGIQPMADVVL
                     NHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(28998..31616)
                     /gene="alaS"
                     /locus_tag="VQ548_000290"
     CDS             complement(28998..31616)
                     /gene="alaS"
                     /locus_tag="VQ548_000290"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HET2653213.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLISPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(31638..32123)
                     /locus_tag="VQ548_000291"
     CDS             complement(31638..32123)
                     /locus_tag="VQ548_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HET2653214.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLLDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(32398..32637)
                     /locus_tag="VQ548_000292"
     CDS             complement(32398..32637)
                     /locus_tag="VQ548_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653215.1"
                     /translation="MKMSTFFNKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILEK"
     gene            complement(32890..33960)
                     /locus_tag="VQ548_000293"
     CDS             complement(32890..33960)
                     /locus_tag="VQ548_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2653216.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNIPAKELLPEETKEDKAFYPDVETMKHLEIYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(33957..34730)
                     /locus_tag="VQ548_000294"
     CDS             complement(33957..34730)
                     /locus_tag="VQ548_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2653217.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(34727..35533)
                     /locus_tag="VQ548_000295"
     CDS             complement(34727..35533)
                     /locus_tag="VQ548_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2653218.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(35514..36671)
                     /locus_tag="VQ548_000296"
     CDS             complement(35514..36671)
                     /locus_tag="VQ548_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2653219.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(36730..37680)
                     /gene="murB"
                     /locus_tag="VQ548_000297"
     CDS             complement(36730..37680)
                     /gene="murB"
                     /locus_tag="VQ548_000297"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HET2653220.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            complement(37792..38544)
                     /locus_tag="VQ548_000298"
     CDS             complement(37792..38544)
                     /locus_tag="VQ548_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HET2653221.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWFEKKR
                     SLEKADALAYGLGHGGLELIFLGLTSLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLTAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(38554..39285)
                     /gene="budA"
                     /locus_tag="VQ548_000299"
     CDS             complement(38554..39285)
                     /gene="budA"
                     /locus_tag="VQ548_000299"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HET2653222.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFLHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            39427..40698
                     /locus_tag="VQ548_000300"
     CDS             39427..40698
                     /locus_tag="VQ548_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HET2653223.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(40718..41533)
                     /locus_tag="VQ548_000301"
     CDS             complement(40718..41533)
                     /locus_tag="VQ548_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET2653224.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEILSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(41690..42343)
                     /gene="phoU"
                     /locus_tag="VQ548_000302"
     CDS             complement(41690..42343)
                     /gene="phoU"
                     /locus_tag="VQ548_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET2653225.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(42355..43113)
                     /gene="pstB"
                     /locus_tag="VQ548_000303"
     CDS             complement(42355..43113)
                     /gene="pstB"
                     /locus_tag="VQ548_000303"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2653226.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(43126..43929)
                     /gene="pstB"
                     /locus_tag="VQ548_000304"
     CDS             complement(43126..43929)
                     /gene="pstB"
                     /locus_tag="VQ548_000304"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2653227.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(43940..44824)
                     /gene="pstA"
                     /locus_tag="VQ548_000305"
     CDS             complement(43940..44824)
                     /gene="pstA"
                     /locus_tag="VQ548_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET2653228.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(44814..45731)
                     /gene="pstC"
                     /locus_tag="VQ548_000306"
     CDS             complement(44814..45731)
                     /gene="pstC"
                     /locus_tag="VQ548_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET2653229.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(45731..46609)
                     /gene="pstS"
                     /locus_tag="VQ548_000307"
     CDS             complement(45731..46609)
                     /gene="pstS"
                     /locus_tag="VQ548_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HET2653230.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(47183..48487)
                     /locus_tag="VQ548_000308"
     CDS             complement(47183..48487)
                     /locus_tag="VQ548_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HET2653231.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEEFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(48488..49261)
                     /locus_tag="VQ548_000309"
     CDS             complement(48488..49261)
                     /locus_tag="VQ548_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HET2653232.1"
                     /translation="MKSKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLASFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(49251..49529)
                     /locus_tag="VQ548_000310"
     CDS             complement(49251..49529)
                     /locus_tag="VQ548_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HET2653233.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGKGKISLEK"
     gene            complement(49529..49930)
                     /locus_tag="VQ548_000311"
     CDS             complement(49529..49930)
                     /locus_tag="VQ548_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HET2653234.1"
                     /translation="MITLFLSPSCTSCRKAKTWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(50140..50757)
                     /locus_tag="VQ548_000312"
     CDS             complement(50140..50757)
                     /locus_tag="VQ548_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HET2653235.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(50747..51520)
                     /locus_tag="VQ548_000313"
     CDS             complement(50747..51520)
                     /locus_tag="VQ548_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HET2653236.1"
                     /translation="MKYKGYLIDLDGTIYKGKDQIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(51531..52268)
                     /locus_tag="VQ548_000314"
     CDS             complement(51531..52268)
                     /locus_tag="VQ548_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HET2653237.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIVEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEESISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(52273..53403)
                     /locus_tag="VQ548_000315"
     CDS             complement(52273..53403)
                     /locus_tag="VQ548_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HET2653238.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(53487..53876)
                     /locus_tag="VQ548_000316"
     CDS             complement(53487..53876)
                     /locus_tag="VQ548_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET2653239.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(53892..54275)
                     /locus_tag="VQ548_000317"
     CDS             complement(53892..54275)
                     /locus_tag="VQ548_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HET2653240.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(54276..55064)
                     /locus_tag="VQ548_000318"
     CDS             complement(54276..55064)
                     /locus_tag="VQ548_000318"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HET2653241.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(55057..55992)
                     /locus_tag="VQ548_000319"
     CDS             complement(55057..55992)
                     /locus_tag="VQ548_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HET2653242.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLSETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(56122..56298)
                     /locus_tag="VQ548_000320"
     CDS             complement(56122..56298)
                     /locus_tag="VQ548_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HET2653243.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(56438..57145)
                     /locus_tag="VQ548_000321"
     CDS             complement(56438..57145)
                     /locus_tag="VQ548_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HET2653244.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            57296..58324
                     /gene="queA"
                     /locus_tag="VQ548_000322"
     CDS             57296..58324
                     /gene="queA"
                     /locus_tag="VQ548_000322"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HET2653245.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIINMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDSMFIY"
     gene            complement(58995..59384)
                     /locus_tag="VQ548_000323"
     CDS             complement(58995..59384)
                     /locus_tag="VQ548_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2653246.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(59438..60145)
                     /locus_tag="VQ548_000324"
     CDS             complement(59438..60145)
                     /locus_tag="VQ548_000324"
                     /inference="COORDINATES: protein motif:HMM:NF019142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2653247.1"
                     /translation="MFRRNLNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGGIIVK
                     VATKPKVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGHVTE
                     QVTVDRKQATDTVIKVPAKSKVEEVLVPCATKYEADNDLSAGQEQEITLGKNGKTVTT
                     ITYDVDGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEIPIETEYLDDPTLDKSQE
                     VEEVGEIGKLLLLQSIL"
     gene            complement(60845..61396)
                     /locus_tag="VQ548_000325"
     CDS             complement(60845..61396)
                     /locus_tag="VQ548_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2653248.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDIEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(61794..62618)
                     /gene="nadE"
                     /locus_tag="VQ548_000326"
     CDS             complement(61794..62618)
                     /gene="nadE"
                     /locus_tag="VQ548_000326"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HET2653249.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(62615..64075)
                     /locus_tag="VQ548_000327"
     CDS             complement(62615..64075)
                     /locus_tag="VQ548_000327"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HET2653250.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(64191..64679)
                     /locus_tag="VQ548_000328"
     CDS             complement(64191..64679)
                     /locus_tag="VQ548_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653251.1"
                     /translation="MKNRFYYYQLLDEREEQLINKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(64669..64878)
                     /locus_tag="VQ548_000329"
     CDS             complement(64669..64878)
                     /locus_tag="VQ548_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2653252.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(65268..65710)
                     /locus_tag="VQ548_000330"
                     /pseudo
     CDS             complement(65268..65710)
                     /locus_tag="VQ548_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000640911.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(66002..66808)
                     /locus_tag="VQ548_000331"
     CDS             complement(66002..66808)
                     /locus_tag="VQ548_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2653253.1"
                     /translation="MILKDINFALNKGEIVGLVGRNGVGKSTLMKILVQNNQPTSGNI
                     ISSDNVGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDLTQSINKKV
                     KTYSLGTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLAVLKKLALNENVGILI
                     SSHKLEDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGD
                     IVQEEGLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
     gene            complement(67214..>67315)
                     /locus_tag="VQ548_000332"
     CDS             complement(67214..>67315)
                     /locus_tag="VQ548_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET2653254.1"
                     /translation="VPQPVQSGDMVRALKEGLINLYKEDGTSVTVRA"
BASE COUNT        20053 a        15155 c        12519 g        19588 t
ORIGIN      
        1 acctacggct agcttcctag tttgctcttt gattttcatt gagtattaca gtaaacaatt
       61 tttctagcta ttgtaacaaa aaagtcactc gaaggcaact tttttcgtcc ataaactttc
      121 aaaagagaat ggcttattca gaactaaaag ccgcagcttt ttgcatttgg taatacttac
      181 cctttctatc catgagttct tgatggttac catattcaac aatatcacca tctactaaga
      241 caagaattaa atccgcatcc tgaatggttg acaaacggtg agcaatgatg aagcttgtgc
      301 ggcccttcat gagttttgca aaggcatcct gtaccagcac ttctgtccgt gtatcaatgg
      361 aagaagttgc ctcgtctaag ataagaatct ttggaatagc cagaaagact cgggatatgg
      421 tcaagagctg agcttggccg acagagagag attctccagc attttccaac ttggtatcgt
      481 atccctgtgg caactgttgg atgaaaaagt ctgcattagc tgctttggca gcagcaatta
      541 cttgctctcg actggcttca ggattgccaa aggcaatatt atcatgaatg gtcccttgtg
      601 tgagccaggt ttcttgaagc accataccaa actgctgtct caatgatact cgtgtataat
      661 cataaatgga ttgcccatcc agcaagatat ctcccgagct aatgggataa aaacgcataa
      721 ggagattgat aagagttgat tttccagcac ctgtcggacc aacgatggct accttactac
      781 cagctggaat atcgatagac aactccttaa tcaaaatttt ttcaggatgg tagccaaaag
      841 agacatgttt aaaggaaata gctcccttaa cttggtcact ggtcaagact tccttacctg
      901 tttcagccac ttcagggcta tctaagaccc catagatacg ctctacgcaa gccagagcac
      961 tttgcaactc agctagcact gaagaaatat cgttaaaggg cttggtgtat tgctgaacat
     1021 agttcaaaaa agtcactaaa cgaccgacgg tcaaggttga acccatcatg atacgataag
     1081 ctcctactcc agctaaaagg gcataaatga gtgcatttac aaagcgagtc gaaggattga
     1141 ccgttgaaga ataaaagatg gctgactgag aatagcctga gtagttgtca tgagcctcac
     1201 gcaatctttg gataaattct gtttgagcat tgaaggactg gattatagtc tgctggctaa
     1261 gcgattcttc aatcaactga gtctgaattc ccctcgtctc tgtttgcttc tggaagagat
     1321 gataggatct cttggcaata aagcgtgaaa tcaccatgga cagtggcgtc aacagcaaga
     1381 ctaagagagt catgaggaga tgaatttgga gcatggctag aatactaacc aaaatcatca
     1441 aaacaccaat gaaaaattgg ttaaaaatca tggtcaagcc agctgccaac tgttcgatat
     1501 ccgtggttac acgactgacc atctctccat tgccttgccg atccgcaaaa gcaatcggta
     1561 accgatggag tttatggatg attcgctctc gtaaatctct ggtataagag aagattagac
     1621 gattatagag gagaggattg gcccattgta ccagagtatt tcctattacc accaagagca
     1681 tctggagaaa aatctgccaa aaaactggtg atgaaccagc cactaggact tggtcaatga
     1741 cctgcccaat cagaataggt aggtaaattg ataagccaac ttgggcaata gttcctagaa
     1801 aggctaggaa aaggaggaag ggatggtttg ctaaatctac gactaaacgt ttgagcgtct
     1861 ggtttacagt ttgtcgtttc attctagtcc tcctttccat gttgggatgc attgatttca
     1921 cgatagactt gactggattt catcaagtca tcgtgcttgc caacagctag caactcacct
     1981 ttttccaaga ggagaatctg gtccgccatc tggagtgtcg aagtccgttg agaaatcaag
     2041 attaagctca tatttggcag attttcgcgg atagctttca agagcttgga ctctgtaatg
     2101 gtgtccagtg ctgaggtcgc atcatctagg atgagaaacg gagcctggcg caagactgct
     2161 cgtgcgatag acagcctttg tttttgtcca cctgagaaat ttcgccctcc tgcttcaact
     2221 agagcatcca agagtccttc cttatcactg acaaaatcct tagcttgcgc aatctccaag
     2281 gcttgccaga gttcttgatc agtcacttct tgatttaaac ctaaagtcaa gttggaacga
     2341 atagttccct taaagagttc gaccttttga ggtacatagg caatccaaga ccgccactgc
     2401 tccaaattaa gaggactacg tccattttga taaaggtcaa tgttcccctt gtctactgga
     2461 taaagtccaa gtaagagttg caccaagctt gatttaccag aaccagtccc cccaatgata
     2521 ccaaggattt gtccttgagt catatcaaag gaaatgtctc tcagagaagg ctgggccgca
     2581 tcaggatagg taaaagtcaa ttcttggact tgtaaaaccc gaccactggt aacttgcttt
     2641 tgttctaatt ctgaatggat gttttcggga gattccgcaa agacctcctc gattctcttg
     2701 gctgagatat aggactggtt gagggaattg atcagcatgg ctagcttgac caattccacc
     2761 aaaatctgta agaggtaatt gataagagca atgagagcac cttgactgag tactcctcct
     2821 tgaattgaaa tatagccttg ccagataata acgagaagag ttccattgac aatcagatag
     2881 gtcagaggtg ttaataaact agacaagaaa cctgtctttt cttgtaatct agcataaact
     2941 tggttaaggg tttgaaaaat ctgtaactct cgtttttctt gaccaaaagc acgaataacc
     3001 cgcatccctt gcaattgctg gcgcgtttcc tgaaccagtt ggtccgtttt ctttctgaga
     3061 ctactgtaga gaggattgac caatcgagat aaccctacaa tgacaatggt caaaatggca
     3121 accatgacta agaaccagaa agtcaactca gctgagattc gataagccat aaaaatggca
     3181 ccaaaaacga taatgggcgc tcgtaaaaag agacgcagga attgattgat accagtctga
     3241 atctggtagg tatccgaagt caagcgagta accaaactag aagttgtcag acggtctctg
     3301 ctgtcctttg gcaaggaaag aatatgacga taaagatcgt ttgtcaattc cttagcaaaa
     3361 cctactgctg cctttgctga gtaaaattga gctatcaagg ccactaaaac gccaattact
     3421 gcaaagataa ggagcaggcc aatctgcatc cagagatgac cttgatctcc ctgaggtaaa
     3481 gattggtcaa caatcccagc aatcaccatg ggaaccaaga gctcaaaaac agcttctaac
     3541 agcttgaaca agggggctaa aattgattcc ttgatgtagg gtttgaagta agataatagg
     3601 tgtttcataa atcccttcta ttcatattct agaaatgaag aaagtgggaa gccccactct
     3661 ctgttttatt tgtttaagta aggcaataga tagccatatc ctgctttttc catctcatcc
     3721 ttggccacaa agcgtaaaga agcagaattg atacagtaac ggaggccgcc taactcccgc
     3781 ggtccatctg tgaaaacatg acccaagtga gcactgcctg aacgagaacg aacttcaatt
     3841 cgctccattc catggctcag atccttgtaa taatgaatca actctttgga aatcggacgg
     3901 ctaaaacttg gccaaccaca acctgaagca aacttatcct tggcaaaaaa gagtggctca
     3961 cctgtcgtaa tatctacata aatcccctct tcaaaggttt ggtcataggc attggtaaat
     4021 ggagcctctg tagcagcttc ttgtgtgaca cgataagact cttcagatag actggccttc
     4081 aacacctctt gactaggctt ttcatagttt gctgcatcaa tcaatggctt atcagcatcg
     4141 gtcacatcga tatgacagta acctgaagga ttcttcctga gatagtcttg gtggtagtct
     4201 tcagccagaa tgtagtggcg taattgctcc acttctactg caatctttcg acccagcatg
     4261 cgttcctgct cctgcaccac tgtgtagata gctggcaaat ctgcttcatc ctgataataa
     4321 atcccagttc gatattggcg accacggtca ttcccttgtt gattgataga tagaggatcg
     4381 ataactcgga aataataaag taaaatctct ctgagtgaca cttccttctc atcgtaaatc
     4441 acttggaccg tttctgcatg gtctgtttcc ttgatcaact ggtaattggt cgtttcgact
     4501 tgaccattag cgtagccaac actggtttct agcactccag aaatgcgtga aaaatattcc
     4561 tctaggcccc aaaaacaacc acctgctaga taaatttctg ccatctttat ttctccttta
     4621 tcacgttttt aactaatact cttcgaaaat ctcttcaaac cacgtcagcg tcaccttacc
     4681 gtaggtatgt tactgacttc gtcagttcta tctgcaacct caaaacagtg tcttgagctg
     4741 acttcgtcag ttctatctgc aacctcaaaa cagtgttttg agcagcctgc ggctagcttc
     4801 ctagtttgct ctttgatttt cattgagtat aaacttcttt tcacaaaaag gatatgaaac
     4861 cctctggtca agagtttccc catcctatct tctattcttt attttgcttc tacacggaca
     4921 cctttggtat caactctcaa gtcatgcagt tttcctttga aaggttgctt ttccaattct
     4981 gccttaattg ttggcatctt gtcatgagaa gccagaacca taactgtcgg cccagcacca
     5041 gaaaggtagg ttgcataggc cccattttct ttggtcactt gcttaatcat cgcaaattct
     5101 cttaccaagt cctgacgata gcgctcatgg aagaggtctc cctcgattgc ttgcccagcg
     5161 gtcaccatgt ctcctgccaa caaggcagca accgctacat tggcgataga acttgcagca
     5221 acagcttcct tataagacaa ttttttaggc aagacactac ggctgtcgcg agtacgtaat
     5281 tcatagtttg gaatgtaagc tagaaaatca cactctggaa agtctgctac gatagcagag
     5341 acttgccctt caacagaact tgcaataacg agattaccat aaatggctgg agccacattg
     5401 tcaggatgcc cttcaatctt ggtcgctaac tgcaattttt catggtctga taagttgagt
     5461 tgacccagtt ggttggctag ttcaatccca gcaacgataa ccgagctgga agaacccaaa
     5521 ccgcgcgcca aagggacatc actggtcatt ttcaagcgtc ttggttgcaa gtctggtaca
     5581 atttgcaaag cgattttaag caagagatta cgctcgtcat gtggaatcca tttgccaatc
     5641 tggtgttcaa tcagccactc atctcgttct tcgcagacct caatttgaag atacttggtt
     5701 acagctacac cgaccgagtc aaaacctggc ccgatattgg cactggttgc aggtacaata
     5761 atcttcatct tattctccta gcaccttgaa ggtattcaag aggtcgaatt ctgaaacctt
     5821 cttcaattca gctgagacat tttcaagctg ggctttatta atcttgtgtg tgatgataac
     5881 gacacgcgcc ttgtcaccct ctttgccatc ttgaaggatt tgcttaaagg aaatatcttg
     5941 agcattgaag atttcagcca acttcaagac ctgacctttt gagtctagag ccaagattga
     6001 gaaatagtag tttgctttga catcttcagg atttgccaag accaagtcac ggctatattc
     6061 gttgaagtct ttgccaatag taccatcatt caaacgacga acgatacgga caatatcagc
     6121 tacaacactt gttgcagttg gtttttgacc cgcacctggt ccgtagtaca tagactcacc
     6181 aataccgata gattctacaa agacagcgtt cattacgcca ttcacactag caagtgggtg
     6241 cgctttaggt aggaaggttg gagtcacttc tgcagcaata cctgaagaag tttcctcaat
     6301 agaaccaacc aatttcacta cgtaaccaag ctcttgagct acagctacgt cttctggtgt
     6361 gatattgcgg attcccttgt gggctacatc atcaaaggca atcttcatgc caaaggcaaa
     6421 ttggctcaaa ataaccatct tgtaggctgc atcaatccca tctacgtcat tcgtcggatc
     6481 gctttctgca aatcctagac gttgtgcttc cgcaagagca tcatcgtaag accagccttc
     6541 ttccaccatc ttggtcacca tgaagttgga agttccgttg actactccaa gcacgcgcgt
     6601 aattttatca gaagccaagg aatttgctaa agtacgaaga attggaatcc caccagcaac
     6661 tgctgcttcg tagtaaagtg ctaccttgtt agcttgagcg atttctagca attctgcgcc
     6721 atggacagct aaaaggtcct tgttagcagt aacaacgtgt tttccagctt ccaaggcacg
     6781 agtgataaag gttttagcag gctcaatacg ccccatcaat tccactacga tagtaatatc
     6841 ctggtctgat aaaatatcat ccacattggt tacaaagtta aagtcattcc ctgctgcaag
     6901 caagcgattt ttttcatctt catccttgac caatacctta gcaactttga tatctgaatg
     6961 tgctgattga ttgatttttc ctccattttc ctttaggagg aaaggcacac cacttgcaac
     7021 ggtaccaaat cctagtaaag caattttaac tgtcatcttt atctcctcga aattttctaa
     7081 tatagccatt ataacagaat tttgtgaaaa ttcctattat agtaaatcac tatttcagta
     7141 taaaaagaaa aaacgaatca gacgattcgc tcttcttaaa atctgaaaat agctttccag
     7201 aaaagattag ccgatttttt gcagattgag cactgcatcg tgactcatca agacttgacc
     7261 atactcttgt aagactgagc gactgatatc actatcgtct gcaaactcgc gcatacgggc
     7321 caacagccaa gctggatatg ggcttggatg attttcaata tccactaaaa tggtcaaata
     7381 atagcgctcg ttcattttgt agagttcaga agtttccatt tcaaaagtca ctgtcttggc
     7441 aaaagctacc aagtcagcca acttagcaaa agaaaggatg tagtagatgt aaggttcttt
     7501 cttactctca gcttcttgtt cagcctgctc ttgctcttct tccttggctt caacttgctc
     7561 aagagattga atggcttcga tatcatcctt ggttttgtct gcgatgcttt tttccagggt
     7621 tttgataaat tcatctggag acatttgagc caattcttcc atatctggca aatccgataa
     7681 gtcttcaaaa tctagatttt ggtcaatctt tgacttggtc acaaagacat ctaccttatc
     7741 aggttttgga gtcacacgga agctcaacat gcctgtatcc agaaagctat caggcatctc
     7801 tagctcatcc aagatagcat aaaagaactc ttctgttttt tcttgaggaa cgagaaagtc
     7861 agcaatctcc attccacgat ccatcaaatc ctctaaagac atcgtgattt ttaaagttgt
     7921 atcactaatt tgtttcattt tcattgctag taacctcata ctttcagttc tatctattat
     7981 actagatttt tacgatttta tcaaaagaag gctcctctat acggatagat tttccctagg
     8041 gtctttctat aggagactcc aagagaaaat ttctgcagac agatagaaaa agccttcaaa
     8101 atcggctaag agccgatttt gaagacctta tacatcagaa tacttataat ttaaaggttg
     8161 ctacaccgag gatagaacga tttaagtttc tgagaatttg aagactttgc tcaaatttct
     8221 tataacgagt cactccgtac tcttcaacaa gaaggactgt atctctttcc aaaagagatg
     8281 atacatcctg taaatctaca aaatgcattc cttttaaagc ttcttgactc tgtttcaatt
     8341 tatctaggat agctttattt gagctaacga tggtcaattc ctgtccagta tttttgtatg
     8401 acaaaacatc tgctaggtta gcaattgttg taatctctgt tacaaaatca atttgatact
     8461 gagaaaaatc acctactcta ttgattgttg gattaaagag ataaactaac acatttccca
     8521 tcacaaccaa aatcacacaa accactccaa taacaactaa acgaagaatc agatttttca
     8581 catttaagcc aagcgctgtt tcaccatttg cgttcaattc tttagagttg atggtttcca
     8641 gtttttcaat tttcacattt gcataggcat gtttaaattt ctcaatcaac ccatcaattt
     8701 ttttctctaa caagtcattg gcatctttac ttgatgtcaa aattttcaca ccaacccctg
     8761 catcgtcaat catatagtag acggtcaatt ttttccacca atagtcattc gttgaatttt
     8821 tcaaggttgt ttctgtcgtg tctaattcac tggcaatttt tttcaactca ctgggttcta
     8881 catcattgaa aagataagct ccattcaaat taccatcaat caatttccca taaaaatcac
     8941 tataaccacc aatttgatga ttcaaaatcg ttttggccga ctcttttgga ggagtgattt
     9001 tatagataag ataagttgaa taacttgttg tatctttgac agtgttttta ttcctaactg
     9061 ctttaattgt aaatggtaca gcaatgagag caaataaagc gatgagagct aaaatatttg
     9121 cttttcgctt tttataaaga tttgcaaaca aatcagctac tgaataatgt tcaaacatga
     9181 tttttttctc ctttgtttag tagatactag ttttcctttg taagcatttt tgctataaat
     9241 ataatcacaa gaacaattcc ccagaattgc attgtaaata aattgaagaa actttctgaa
     9301 aagctgcttc ttggcataaa gaatagatta ttcaagatga gtagggataa agcaaatagg
     9361 attgtccttg agcgataggc tacttgcagc atggctataa ataatacgcc gagtaagaaa
     9421 ctaagcagaa agactccaat cataccatag tcggtataca actccatgat ataactactt
     9481 ccgataccat gccctttcag gtattccttg ttcaagacaa gataggatag attgtgggca
     9541 taactattac tatcaatagc tagttccaca ctattggttg tatgttcaaa ggcttttcct
     9601 ccgaaaatgg ctcccaaact cccccttgca aaataatcaa gaacaggacc aaaagtaaaa
     9661 ttacggaaat ctcggtaagg gaggctactg ttaaatagaa aacctcgagc cagaacacca
     9721 aaactagtcc cttgtttata gataaagtca agtaagatat cccagaaacc tgtatgggaa
     9781 acttggacat tatcccgtac ataattgagt actcccatcg ctaacatgag aataggagaa
     9841 cctacaaaaa tcgctaactt ttctttaaac ccaatccatt ttcctttttc agtttgctcc
     9901 cgcataaagt aataaacaaa agcaaataaa atacttaaaa taaagggatt tcgtgtccca
     9961 attgccaaat gaatagtatt agctgcaata aaggagacaa gcactgctgt ggcctgcaat
    10021 ttctttggct tggttgccag atacatacac attgcataga ccgtaaaggt agacaaaatg
    10081 taggtaaaat aaggcagttt actttcaaaa tttgcatagt aggcatagta ggaagtctgc
    10141 aaacgataca agagccgttc aaataaccga atgaaataga aaggataagt tagaagaaaa
    10201 actcctagtg atacaaagcg taaccgcttg atataaacct cttttagaga atttcctata
    10261 tttgctactt ttattttctt cctagctatg aagtaacgag ccagaatgcc tcctgtggtc
    10321 aagcccagaa tcgaaaccat gacaactata aaggcaaaac gataggctat tggatgatag
    10381 gtatccaaag caccatccct aaaataatca atggtcggtc ttgataccag aaatacaaaa
    10441 atggttaaat agaaaataaa atggattaag taatacttga tatcattcca acaagcaatt
    10501 aagctactaa ccaacaagaa caataaagta gaaagtaagc taacattatt attattaaac
    10561 agatacacaa ttccacttac tagcgtcaag gcataactga ctatggtcaa actaaataat
    10621 aatcgtttcc catcaatcac ttggtcaccc ccgttctaat gtaatttttt agatttttca
    10681 atatttttca gtaataagaa tcgatataag gaaatattta tgaatagggc caaagcacta
    10741 attcttctcc ccttacggaa aattggattc ctagaaatag caaaggcatg gccttttaaa
    10801 aaacgatgaa tctgagaata ggcttcaaac tgtttatact gatcatctag caacatctta
    10861 tccagaataa agaagtgggc ataggccaat ctgaaaaaag cgacctcttt caagtcagga
    10921 tagtttttca caacttcatt ataaaacttt tggtagatat caatataggc taaatccttc
    10981 tctgcatagg gtttggtcgt aatactatcc cctctatgga aatagtaata atagggttta
    11041 gtattaacca catacttctt ggccaacttg attaaatcaa aatggtaata ggcatcttcg
    11101 taaatcaacc ccttaggaaa ggatagggca gttgcaatct gtctcttgat tagcttattg
    11161 caaatcgtcc caggtatttt ttcacctatg aggtattcct ttagaaatgt ttgagaatca
    11221 cagacaaaat agtcatcctg attggctgac tgtgggcttt catcattagc atagacattc
    11281 atgacaccac agcttgaaac atccgcatct tcttgaacta attgctcata taagctctga
    11341 atcatttctg gatggatata atcatctgag tcaataaaaa tcagataatc cccgtgagcc
    11401 tgcttcatcc catcatttcg tgcttgcgac aatccttcgt tctttttatg aagcactgac
    11461 accctgtcat cttgttcagc gattgagtca cacaagcgac cactttcatc tgttgcacca
    11521 tcatcaacaa gaataatttc cagattttga tagatctgct tctgaatgga agctatcgat
    11581 ttttctaggt actgcgccac attatagact ggcacaatca cactaattaa tgcagtttcc
    11641 atgctactcc tctaatagtt tttctacttg ttcgatttgt tttgtaattg taaattgttg
    11701 aatgaattgg ctagcctcat cgacatcaaa gtttgaggca gaagtcatgt aattagtaat
    11761 cgcctgagct gcctcttgat tgctctcaat gatttgtcca aatcgtcctt cttgggataa
    11821 ttcctcagcc cctccaacgt ccgtagagat aaaagggagt cccagactca aggcctccac
    11881 atacactcca ggaaaacctt cttgtttaga catagacaag agaactttcg tctgagataa
    11941 atactgataa ggattttttt gataaccaag gaaatgtaca tagtcctcaa tcccatactc
    12001 tttgactcgt tttttcagtt cctcttccat atcaccagcc ccgataaaat agagatgata
    12061 gttttttccc tcttggtgta ataatcgtat cacttccact acacggtcag aacccttatt
    12121 ttcctcaatc cgtccgatag tacagatact ttgaggagca atctcgatat cgatcttctc
    12181 ttgagatttt tctagaatag tctgaaaatc atatccattg tagattatct gtaatttaga
    12241 agcataatct ggataaactt ccttgataga attgctggtc ttttttgaaa tccctacaat
    12301 tgtattcgca gcatccaact ggcttctatg tgattctctt ttagagctat ccttaagaag
    12361 ttcttcaata cttccatgaa tccaagatat cttcttgact tctcttcttt tagagaacaa
    12421 cagtggtgga ttcataatgg taaaagaaac ttcaacatca taatcatctt ttacaagcaa
    12481 acgacgagtc agtcttggaa aataaattct cattctccac aaaaaagctc gtaaccatct
    12541 ggtttggcga taatcttgaa gggattttaa aatgcgtaca tgctttggaa cagattcata
    12601 tcccttgtca aagtgctcca tttcaagaat atcaatatca tacttttcta gatccagatt
    12661 tgaaacaatg gttgatagaa tcttctctgc accacctcca agagaaaaag accacataaa
    12721 aaataagatt tttttcttag ccaccatatt ctcccttgta ttctgtataa gacttatcca
    12781 tatcagcgat gacagcatca tgatgcggta cctgcttgtc tgctggtgga ggcgtcatat
    12841 aatccccaaa agcagttctg agatagacat catagccgat tggaataggc atctctgttc
    12901 cttcaaatgg caagaaaaga ttgtcttcaa aagatgtgat tgggtacttg tttctcatgt
    12961 agccaggacc tgagcataat tctgtaatgc catcacaatc agccaaatca tacttagtca
    13021 tttctttctc agcttttttc cagatgcgat aacggagaga ttttggagtc aaacccagta
    13081 aaatgcgact tccccatttc atgagagcac catgcttttc tggaatagtt tgcgcacaaa
    13141 agagtgaata aatcaaggcc caacgaacct gttttttccg ctcagctgga tttttcggat
    13201 aataatccaa aggcaaaaca tccaaggtca gaccatgtgg caaatctaaa tcctgctgat
    13261 aaggcttgat acaggtggtt tccttgtcac gaatggtaat aaaaagatta cgatcaacaa
    13321 aatccttgtg actctttgac aagaaataac gttcatctgc ataacgaggc cataattctg
    13381 ctaatttctc ataatcttta cgaggcataa aaaagtctag gtcgtcgtcc caaggaataa
    13441 atcccttgtt tcgaagggca ccaatagcgc ctccgccaca gagataacag agcaaatcat
    13501 gttctttaca aaaggccaca aaatattcag ccatctccag actacgagcc tgaattgctt
    13561 ttaaatcagt catattgttc attattcttt ctatcgtatc gtttcattat accacaaaca
    13621 aggggtgaaa atctattgca gactgtaaaa aatcaaagcc tgactgctat ccaaatagct
    13681 atcaaacttt gatttttctg tcttatactc ttcgaaaatc tcttcaaacc acgtcagctt
    13741 caccttgccg taggtatagg taactgactt cgtcagtctt atctacaacc tcaaaactgt
    13801 gtttttagca gcctgcggct agcttcctag tttgcacttt aattttcatt gagtattatc
    13861 ttatctcaag cccatttgag cgagcttggt ttgatatttg ttttgatcaa ccagcaagcc
    13921 caagcctcca taaacatcat aggcatctac ccagtcaccc agttctggaa tcgtcaattt
    13981 ttcaatacca ttttttgctc catccaaaac agataaaccg tttgttagga ggaaagtata
    14041 gggtacgttg gttgaggtca tagcaaaaac ctttccaaga gcttcagaac cagtgaaaag
    14101 tttagtggga tctttaattt gctctaaaat tgctgttaaa acttgttgct gtctttttgt
    14161 acggccgtaa tccgcctcat catcatcacg gaaacgagca taattgagca gggtcgagcc
    14221 attcatctgc tgttttccga ctttaatggt ttgggttgga gactcagtct cggtagcgta
    14281 taaatcatct ccgactgtag cttctgttag gggacgccca ttcaatgttg aaaattgagc
    14341 atcaatcgtc accccatcag ggaaaagcgt gtcaatcgct gtggcaaagg cctggaaatc
    14401 aaccaaggcg tagtacttaa tgtccaagtc aaaattatct ttcaagactt ggcgaaccat
    14461 ttctgcccct ttttgcccct cttgttctcc taactcgtag gctacgttta acttgttatc
    14521 tgtctgtttt ctaccattaa tcacttgact ataaccatct atatagacca aattatcacg
    14581 catgaaactg actagcttca ttttcttatc tgagcccccg acatttaata ccataataga
    14641 gtcagttcgt gtctcaacac tgttctggcc gattcgacca tcagtaccca tgattaaaat
    14701 attaactcca tctctagtgt cctgaccatt aaagacttct acttgagctg cccgggcatc
    14761 agcagttttc tttgcgctag catcttggta accacgcaaa aacatgaata ccatggccaa
    14821 agccacacag accaaaagtg aaaaaatcac cataaaaatt cgtttaagac ggagcttccg
    14881 tcttttcttt tttggaggga aagagagtgc ttgtgatttg gattgtgagc gactccggtt
    14941 cgcatagctt ggtaagtcaa cctgctcttc tctttcttgt tccaagctag agctactatt
    15001 tcccctagca agagttagct tttcttgcaa ataggcaaac tcattttttt ctctctcatt
    15061 gagatagtga atatttttta gcaaataatc ataacgcaac tgctcatgat gacttaaggg
    15121 attttcttta ctcatcttct ctcctttcca tggtctgata ttggataaat aggataggca
    15181 cccagaattt tatactggat tccaatcgct tctaattctt tttgggcaaa gtggaccaag
    15241 tccttatcga tataatccac atcgataatg aaaaagtatt cacccagtgc tgtcttgagt
    15301 ggacgacttt caatttttgt caagtcaatt cctcgccaag caaaggtcga cagggcctta
    15361 taaagtgcac ctggaaggtt gtcaggtaat gtcaaggcca aactcatctt ttcagtttgt
    15421 gcttgcaagg gaatactagg cttttcagct cctagaaccc agaaacgtgt gaaattggct
    15481 tccatttcct gaatatcctc ggcaatcagt tccaatccat attcttcagc agaacttcta
    15541 ggtgcaactg ctgcaaaggg ctggtctgga tgttcggaaa taaaacgggc cgcataagct
    15601 gtactagctg ttacctcgat ttgagcctct ggatattgtt catcgatgaa tttctttcct
    15661 tgagccaagg cctgtggatg tgaaaaaatc ttttcaatct tagtatggcc tggaaccacc
    15721 atcaactgct gatgaatagg ctgaacgatt tctgctactg cttggatgtg agcctgatga
    15781 aaaagatagt ccaaggtttc atgaacacta ccctcaatag aattttcaac tggcaccaca
    15841 gaatagtcca ctaatccttg ctcataagcc ttgatgacat ctgtaatgtt ggcaaaagcc
    15901 tgcaattcct catgaggaaa agctgtctgc acaacgtggt gtgaaaatga tcccttggga
    15961 cctagataag ctattttcat cttagttcct ctataatttc ctctgggctt agcttggtca
    16021 catccaaaac ccgactagcc acttcctcat accaagcctg tctttcttga aaaatagcta
    16081 ctagttcttc cttgctatta tttagaaaaa gcggtcgctg attgtcctta tcagctgcga
    16141 tacgtaggta gagggtttca aaatctgctt tcaggtagat gttatctgta ttagtcttga
    16201 gtaagtcacg atttctctga gaaataacca ctcctcctcc agttgacacg acttggtctg
    16261 tttgtagtaa atcagctagg acttctgatt ctacatgacg aaaggctgct tctccctttt
    16321 cagcgaaaaa attcgcaatg gacataccta ggcgcttctc aatcagagca tccatatcaa
    16381 ggtaattagg gtccaagcct cttgcaatag tcgattttcc agcccccata aaccctaata
    16441 acaccttagc catgaatcaa gctctccaaa tcatcaaaga aactaggata gctggtattg
    16501 atggcttctg cacggtcaag ctccacctct ccatctgcaa ccaagagggc tgcgatagct
    16561 gtcatcatgc cgatacggtg gtcaccaaac gtattgactc tagcaccgtg aagagctgat
    16621 ttccctttga taatcatccc atctgccgta ggagtaatat ctgctcccat actatttaag
    16681 gcgtctgcca caacctgaat acggtctgtt tccttgacct tgagctcctc agcatccttg
    16741 ataactgtta caccttgggc ttgagtcgca agcagggcaa taatgggcaa ttcatcaatc
    16801 aatcgtggaa tcaaagcgcc accaatctct gttcctttca agtcagaaga ctcaacaatc
    16861 aaggtagcag atttagcgac tggatcgatt tcagttattt ccaattttcc acccatggca
    16921 cgaatgacat caataatacc ggtgcgagtt tcgttgatcc ccacattctg cagcactaga
    16981 cgagaatttg gagcaatcaa acctgcgact aaccaaaagg ctgcactgga aatatctcct
    17041 ggtacgacca ccttctgtcc tgtcaatttt tgtggcccct ggactgtgat tttcttacca
    17101 tccacactta aatgaccacc aaattgttgc aacatatctt cagtatgatt acgggtgtac
    17161 tctttttcga taataactga ctccccctta gcttgtaagg ctgcaaacat caaggctgac
    17221 ttgacttggg cagaggcaat tggcaactca taatgaatag gtcttaggtt tttcgtccct
    17281 tttaagcgaa ggggaggcaa gtctcgttca gtttgccctg aaatgctgac gcccattttt
    17341 ttcagtggaa gggtcacacg gtccatagga cgtttggaaa gactatcatc tccaaacatc
    17401 tctacttcga aatctgcacc agcaaggaca cctgaaatca ggcgaatcga ggtgccagaa
    17461 tttcccatat taagggcatt ttgtggcgct tttaagccag ccatgcctac accttgaatg
    17521 gtaataaccc catctttatc ctcaatttca acaccaaggt cacgaaaaac ctgcatggtc
    17581 gaaagaacgt cttcacctcg cagaatatca taaaccttgg tctcaccctc agccaaactt
    17641 ccaaagataa tggaacggtg gctgatagac ttgtcacctg ggacgcggat actaccatgt
    17701 aaatggcgaa tgtttgtttt tagtttcata ctggacctca tacttgcaat acttttacct
    17761 attttatcat aaaaagtcag aaattcctta aaaattcctg actttaggat cgttcttttc
    17821 ttatttcagc aattctgaaa ctggttcaaa aacaattttt tcaatgtcag aaaggtaaat
    17881 ggccaattgt tgttgcttgg taaagaattc tgacaagagg ctatttcctt gaatctgttt
    17941 accaaagcct tccatcttag cttggaagga cgcatctggc atttgacctg tctgtgctag
    18001 tttttgaatt tcctcttgaa aggcaagata ttctgtaaag attttgcttg cctcagcatc
    18061 tgctgcaatc gcatctttag ctgctttaac agccttgtat tctggtaatc cgcgtagacc
    18121 gcgactgagt tcgtttgcac tatcgtaaat atttgacatg ttcttctcct tatttgatga
    18181 cgactgtata gtcggtattt tctgttatga gatgctcagc tctttccaag tcttgagcat
    18241 ttttaaatga aatttgtagg attccgtgaa tatcctcacg attttcctcg ttgatgtgga
    18301 tgttaaccaa ggaagttcca cgtagcagtt ccaaaatccg caggatgaca tcttcttcat
    18361 caggaacgtc aacatagagg tcgtaagagc tatccacacc accacgctta tggatttcca
    18421 tggtctggcg ttgttcacgc gcttggttaa aaaagttcca aatttgctct tcatctccct
    18481 tactaatggc ctgaccaatc acttccaaac gttccttgaa atcctcaatt ctatccagaa
    18541 tggtctcgct attggacaag agaatggagg tccacattcc tggctcgctt tccgcaattc
    18601 gggtcatatc tcgaaaacca cctgccgcaa agcgccttgc catctcatgc tcttgagcat
    18661 agaccgcagt ctgctccatg agactagaag ccaaaatatg aggaaaatgg ctaatctgag
    18721 aagtgacacg atcatgctcc ttggcatcaa tctcgataaa acgagcatga agacctgaaa
    18781 gcagatcctt catttcctta agcgtgtcct gacttgtcag gcttgaaggt gtaaagatat
    18841 aataggcatt ttcaaaaaga ttgacatctg ccgaagcagc ccctgtcttg tgactaccag
    18901 ccatgggatg ggccccgaca aagcgaacag acttgccagc caaatactgc tccgccgcat
    18961 ccacaatggt tgacttggtc gaaccagcat ctgaaataat aacgccttct cgcaaatcca
    19021 aattggccaa ctccttaatg aaagcaatag tttgtttgat tggcaagctg aggataatga
    19081 catctgccaa aggagcaaaa ctagcaaaat catccgttgc acggtcaatc ataccttctt
    19141 tcaaggcgat atctctcgaa gcttgactac gattataacc taaaatttca taatctggat
    19201 gatcgcgttt gataccaagt gccatagagg ctccaatcaa cccaagacct gcgatataga
    19261 ttgtttttgc cataggaact ccttaatagt tctttgtata gtctcggtgt ttggctaccg
    19321 cttcttttag ttcctcaaga ttatctgatg agaatttttc gaggatttct tgcgccagaa
    19381 ccgttgctac aactgcttcc atgaccattc ctgcagctgg aagagcagtc ggatcacttc
    19441 tctccacggt tgccttgtaa ggttcgtggg tttcgatatc cacactcata agaggtttat
    19501 aaagagtagg aatgggtttc atgaccccac gaacaacgat gggttgccca ttagtcatac
    19561 caccttcaaa accacctaga ttattggtac ggcgagtata accgtcttct ttagaccaga
    19621 gaatttcatc cataacttgg ctgcctttac gataaccagc ctcaaagcca agaccaaatt
    19681 ccaccccttt aaaggcattg atagagacaa cagcttgagc caatcttgca tccaattttc
    19741 tatcccattg gacataggaa ccaagaccaa ctggaacgcc tccgacgact gtctccacaa
    19801 ccccaccgat ggtatcacca tcacgtttga tttggtcaat atagtccttg atttcctgtt
    19861 ctcgttcttg gttgacaata gaaacttcag actgggcagc tctttgctta atttcagcga
    19921 ctgtcagatt ttcaggaaca tctatttcct taccaccaaa gaccacgaca tggttggcaa
    19981 tctccatatc cagctcagcc aagaggcgtt tggctactgc accaactgcc acccgcatgg
    20041 tggtttcacg agctgatgaa cgctccaaag aatttcgcaa atcatcaaaa cggtacttaa
    20101 tccccccaac caaatcggca tgacctgggc gaggatgagt aattttccgc ttgcttttaa
    20161 ggcggtcttc aatgtcctcc gcagacatga tgtccagcca tttctggtgg tccttattga
    20221 tgacatccat agtaataggc gcccctgtcg tcttcccgtg gcgaacaccc gaagtaaaga
    20281 caacctggtc actctcaatc ttcatacgac caccacgacc gtagccaccc tgacggcgtc
    20341 taagatcctc attgatatcc tcagctgtca atggaagtcc agctggaatt ccctcaataa
    20401 tagctgttag acgggggccg tgtgattctc ctgcagttaa atatctcata cactctcctt
    20461 attttaccaa gtagtctttc atctcttcca gagaaactgg gtgaatggtc gctgaaccaa
    20521 gctctggcac caagaccaat ttcaaggtgt taccacgcgc tttcttgtca tgagtaagag
    20581 cctgataaag cttgtcaact ttccaatttt catagtcaac aggcaagccg aatttctgac
    20641 acatctctgt gatagattgg gtaatgccag ctggcatgag gcctttttcc tcagcaacct
    20701 tggaaatctg taccattccc atggcaacag cctctccatg catgaccttg ccataaccgg
    20761 cagtcgcttc gatggcatgg ccaatagtgt ggccaaaatt gaggtaaaga cgaataccat
    20821 tgtccaactc atcttcaacc accatcttgc gcttcacctg acaagaatgt tcaatcaagg
    20881 tctctgcatg ttccaaaata ctctcaacag aaccattcag tcccgtcaag agagcccaca
    20941 gttctggatc ctcaatcaag ccatacttga taacttcacc catcccttca atcaactctc
    21001 tttttccgag ggtttcaaga acaagtggat caatcagaac cccatctggt tgggcaaagg
    21061 tccccaccat atttttagca aatggtgtgt taacgcctgt ctttccaccg atagaagaat
    21121 caacctgagc tgtcaaacta gtcggaatct gaacaaagtg aataccccgc atataggtag
    21181 aggctacaaa gccagccagg tccccaacaa cgccaccacc aagagcaacg attccatcgc
    21241 tacgagtcag accttgcttg actagaaatt catagacttt ctgaacagta gttaaattct
    21301 ttctttcttc accttctaag aaatcaaaaa cagctacctg aaaaccagca tcttctaggc
    21361 tgagcttgac cttctctgca tagagagagg ctacatggtt atctgtcaca atgactacct
    21421 tttgcggttg ccagagttct cgcaaccact gaccagcctg ggccatacaa cctttttcaa
    21481 tctgaatatc ataaggatga tgaggaatat cgattctgat tttcatagga gagtctccct
    21541 ttctttattg atatttttct gttaaagact gccaaatctc ttctgtcggc attttcttgc
    21601 ctgtccacag ttgaaaagct tctgcagctt gatagagcaa cattcccaga ccattgactg
    21661 ctggattgcc ctgacttcta gcccatttca aaaacggtgt ttcaaagggt tggtatatga
    21721 tatctgcaac taagagagtt tctggtaaga ctatgttttc aggaacagga gaggattggc
    21781 catccatgcc cacactggtg gcattaacta gcaaatccga ctcggcaatc cttgcttgca
    21841 gttcagaaac atattctaaa gcacacaaat ccactttaaa gcctgtctgc tcctgtaact
    21901 tgtctaggta aggtcttgtt ttttccatag aaacggaacg aacaaagacc gaaatctgac
    21961 tgacgccatc caaaatagcc tgtgccaaga ttgatttagc cgcaccacct gcacccagca
    22021 gggtcatctt tttacctgaa attgtaaaag aaggcaagca cttaaaaaat cccttgccat
    22081 ctgtattata tccaattaaa ttgccattct cattgacaac cgtattaacc gcaccaatca
    22141 agcgcgcttc atcgctcagc tcatccaaat aaggaatcac ctgctcctta tagggcatgg
    22201 acagattgat gccaaacatc tggtagcgac gaatattggc cactgtttct accaagtcac
    22261 tcgcttcaat ctcccaagcc acataagcac cgttggtagc tgtcgcctca aaggctctat
    22321 tgtggatgaa gggagaaata gaatgcttaa taggattggc aacaactgca gctaaacgtg
    22381 tatagccatc aagcttcatc caaaatctcc ctgatttttt tcatgctagc tagagaaatc
    22441 tgcccagggg cactaacctc atccagactg gcaaaagacc aactcgaacc agtcacatcc
    22501 gcagtgatac gagagacctt gcccacctta cccatagaaa tggtcacata ttcctgttca
    22561 ggattgagcg ttttaaagcc tcgtgtatag ttcatcaagt ctaagacatc ctgctccgtg
    22621 tgagccatca ccgcaacctt aacaagtttt ggatttagga tcgtcaactc tgacaagatt
    22681 tccatcatgt tctcaggtgt ttcttggaaa ttatggtaac tcaaaacaag atttgggaag
    22741 tccagcattt cctcaaaaac atccttgtag ctatagtact caaaatcaat atagtctggt
    22801 tgatagagtt gcgcaacttc cttgattaga tggatatact cttctggaga aaggtcgatt
    22861 tctccacctt cggagcgagt tcgtagcgtg aaaaccaact cacggcctgc gaatttttca
    22921 aaaatggctg gagctacctg caaaatcgct tctttaggca gatagtcggc acgccattca
    22981 atgatgtcgg catccaggta cctcgtggca tccagagcct gagcctcctc taaacttctt
    23041 ggcattactg aaacgattaa tttcatttac taaccttcat actaatcacc ttgaggtaat
    23101 tactactttc atctttttta ttataggcaa aatctgctgg aagaccatat ttgtttaaaa
    23161 tctggtaact tcttcctgca aagcctttat caatttgttc tgtaaatttc tgacgggaaa
    23221 cattggcagc attggtactg gcaatgataa tccctcccgg atttaaaatc tcaagactct
    23281 gggaaatcaa cttgtgataa tccttggcca cagagaaagt ttgtttttta ttccgagcaa
    23341 agctaggcgg atctaggaca atcacatcgt aggtcaagtt tttgcgtttg gcatatttga
    23401 aatactcaaa gacatccatg actataaaac gacgctcgtc tgtgctgagc ccatttgcct
    23461 gaaaatgcgc ttgagacaat tctcgtgaac gtttggctag atcaacagaa gttgtctggc
    23521 tagctcctcc catggccgca gctactgaaa aagccgctgt gtaggaaaac atattgagca
    23581 aggatttacc catagccaag ccgtcaacta aactaccgcg aacctcatgc tggtctagga
    23641 aaattcctgt catcaagcca tcattcataa agacttgata caggacacca ttttctaaaa
    23701 cagtgaaaaa gtcaggtgct tcttgaccat aaacatgggc agattcatag tccaaaccct
    23761 taaagcggat tttctcataa gcccctaaaa cctcagggaa aacctgtcta aaggcttctg
    23821 atatagtctg acgaatctga taaacataag agttatacca agaaaagacg gcgtagtcgc
    23881 cataaaggtc cactgtcaga cccccaaagc catctccctc ttgattaaag agacgaaagg
    23941 cagttgtcaa atcatcttga tagtaggcgt ttctcttttc tttggctttt ctaaacaacg
    24001 tttcaaagaa agcttgattg aaggccacct tgtctttgct gacaaaccag cccaagccct
    24061 tgttttgctg agaaaggtag gcagtcccaa gaaagtttcc ttcctgaccc tgcacctcta
    24121 cttcctgatc cttaagattg acattctcaa gatcactggc ttctagtaaa actagcccct
    24181 tagcaagctt cttttcaacc cttttgctga ctcttattct attcataact accattatat
    24241 caaactttta gacaattctc aaaaaagaaa ctacccttgc ttttttactc ttcttttaaa
    24301 aaatggtata ctagacttcc tgcaaaacta ggaagtaaat gtgtaagaat cacaataaaa
    24361 aatgctcttc cgtcttggag gagcatttct ttttatcaac gaaaatcaaa taacaaacta
    24421 tgaaactagc ctcaggttaa ctgtgagatt ataggtagag aggttgaatc agcaatatgt
    24481 gtctgtcaaa tttagtgaca aaggtagtag aagaaagatg aagaaataaa tctgcttcag
    24541 tagatatctg gaaaatttga ttttatagaa aagccttttg ttacaaactc aatatactat
    24601 caataaataa tattatagaa gcaacaataa ttaaaatttc acctatttgc atcattctat
    24661 ttcgaactct aaatatatgt tctatcaaaa atacttggat cacacacatt ataggaatta
    24721 acgtttttga aattgaaaaa tatcccaata aataaactat aaacaacaat aatagaacta
    24781 tattatattt cttattcaaa acattcctcc ctatattttt gattaccaat cttaatcatt
    24841 tacaactaca ttctaacaaa ctataaaagc gtttgtcgaa ttgaatttat caagcaagca
    24901 accaactatc tcatcttttt tctatttctg ccaatatgcg tgacaggtaa taatgatagc
    24961 caaaaatagc aagagcaagc aagacgataa gagctcctac tcccaagttg atggcaagga
    25021 taggggagag agactgaacc aagaatatgc tcccaattac aagggccatc aggattgcac
    25081 tataaataaa caataaaact atggcgacta tgccatttga acgattcacc aggtccgtaa
    25141 tgctactcca attggttgac agatttttaa cgtccttaaa gtaatggtgg caagaaagga
    25201 tgacactggc aatgatccag actacaagaa ggtaaatcat cgaaaggatg gacaagccta
    25261 gatatagaga aagaccgagc aaagtcagaa ctggtaaaaa ggactgaaca gcaaagataa
    25321 tccaaaattt cactttcaca taacgagcaa agtcaaaggg taaactcttc agaaaatcaa
    25381 cattttccct ctccaaggac aaggcaattg aatgcaggct ggtgatattg ttattgacaa
    25441 ctgctataaa cactcctaca aaaaacaagg gtaaccagta tggaggatga atgtctggaa
    25501 ctatctgaga atctcggatt ttggaaatca gactgatcat catgagataa ggaaggaaag
    25561 cacttgtaaa aagcactgta atcacaccag tcccctatcc caagagggtg aggtggtagc
    25621 gtaaaaccat acggaaaaag ccctttttag tagttgaaat cctctccttg ctgcgacgtt
    25681 cttttttgac cttctcctca ctgttaagca ggatcacgtc ataaaaacga ggaaggacct
    25741 tctttttggt cagataaagc aggaagagag ttagtcctat ccaagcgagc agacccacta
    25801 aggcttctgt cgaaaaaggc tccactgcta ttttgtaaaa gatatgaaga ggataaagga
    25861 gaaatggaat gtctctaact ttgtcaacaa tacttccaaa agtcgactga agaaagaaga
    25921 taaatattaa aggtatgaga actcctatcc caatcatcac attcgaaaaa atagactgat
    25981 actttctgaa gaccctagtc tgagccaaga aatgtactgc cactaccgtc actaaagtaa
    26041 cagagacaaa taataaggtc aaggacagta gcatcaaagg caaacccagc caaagagaag
    26101 gagctagact aatatagagg gctagaaaat aagctaggat tggtacaatt ccagttagag
    26161 ctggcaagag gacagacaga cctttggcca ttataatctc tgattcttta aaggcatagg
    26221 gcctatagga ggccaggtcc ttactctcat aaaagacatt gtaaaaggca gtgaaagaag
    26281 ttgaaaaggc cagcaccagt aaaatagcaa ccatcgagct aaaataaata ggtatttcct
    26341 caaaaggaaa atgaatggct atattactaa aacagatgag catcaagaga ctggaaaaaa
    26401 tgtaagaact taggactcta gcagaaacat ttactttttt cccaggattc ttagcctgct
    26461 tctttcgtag attagccaga ttagcttctt gagatgaata gaggatattg atatcaacta
    26521 attttttaat gaccttgaga cgcatccgca acctcctctt ttctaccagc aagactaagg
    26581 tagatacttt ccaaaaactg gtctgggtgg tctttcctca agttctctac actaccacaa
    26641 tagatcaaat gccccttttt caaaatagca atccgatcac agacttgctc ggctacctca
    26701 aggacatgag ttgaaaacaa gaccgtcttg cctttttgtg catgttcctt catcatttgc
    26761 ttcaaatcaa aggcggcctg gggatccaaa ccagtcaagg gttcgtccaa aacccaaata
    26821 tcaggagcag acaagagtgc cccaatgaca aagactttct gacgcattcc gtgagaaaga
    26881 gtttcaataa cctgatagcg gttttcagca aaatcaaaaa cgttcaatag cctagctaga
    26941 ctagtctcca agtcagagct agtcagatca taggatgaag cgatcaattc ccaaaattca
    27001 ttggccgtta agcgtaaaaa taagtcaggc gagtctgcta cgtagccaat ctttcgtttg
    27061 atcgccaagc gattttccga taactcctga ccgtctacca aaatacgacc actgctgggt
    27121 gaaatgatac tgactaggga ttttatggtg gtcgattttc cagccccatt atgaccaatc
    27181 aagcccataa tctctccatt ttcaatctgc aaattgagat tactcaaggc ctctttatca
    27241 ccatacaact tactaacatt ttgaaattca atcatgggac aactcctatc tttatctgta
    27301 ttatacatcg ctatactagc actttgatac aaaaaaatca atactttatt ttaagtagtt
    27361 aaaatagttt ccttctatct tacgcaaacg tttgcgccga gagatacttt atgatagaat
    27421 aaagaacaag attgacaagt aagaggaaac atcatgcaaa atcaaacact catgcaatac
    27481 tttgaatggt atctgcccca cgacggtcaa cactggacgc gtctggctga aaatgctcca
    27541 cacctagctc atctggggat cagtcacgtc tggatgccac cagccttcaa ggcaaccaac
    27601 gaaaaagatg tcggctatgg ggtctatgac ttatttgact taggagagtt caaccaaaaa
    27661 gggactgtcc gcaccaagta tggtttcaaa gaagactatc ttcaagccat tcaagccctt
    27721 aaagaacagg gaattcaacc tatggccgat gtagttctca accacaaggc tgctgccgat
    27781 aacagggaag cctttcaggt tatcgaagtt gatcctgtag accgtacagt tgaacttgga
    27841 gaacccttca ccatcaatgg ctggactagt tttaccttcg atggtcgcca agatacctat
    27901 aatggcttcc actggcattg gtaccacttc accggtacag actacgatgc caaacgcagt
    27961 aaatctggga tttatctgat ccaaggggac aacaagggct gggctaacga ggaattggtc
    28021 gataacgaaa acggaaacta cgactacctc atgtatgccg acctagactt taaacatcct
    28081 gaagtcatcc aaaacatcta tgactgggct gattggttca tggaaacgac tggtgtagct
    28141 ggtttccgtt tggatgccgt taagcatatt gactctttct ttatgcgcaa cttcatccgc
    28201 gatatgaagg aaaaatacgg tgacgatttc tatgtttttg gtgaattttg gaacccagac
    28261 aaggaagcca atctggacta tctcgaaaaa acggaagaac actttgacct tgtcgatgtt
    28321 cgtctccacc agaatctctt tgaagccagt caagctggcg caaactatga ccttcgtggc
    28381 attttcacag atagcctggt tgaactcaag cctgacaagg ctgtgacttt tgtcgacaac
    28441 cacgataccc aacgaggaca agcccttgag tctaccgttg aagaatggtt caagccagca
    28501 gcctatgccc tcattttgtt acgccaagac ggccttccat gtgtctttta cggagactac
    28561 tatgggattt caggccagta tgctcaagaa gatttcaaag aaatccttga ccgcctccta
    28621 gccatccgaa aagacttggc ctatggagaa caaaatgact actttgacca tgctaactgt
    28681 atcggttggg tacgttcagg tgctgaaaat caatccccaa tcgcagtcct tatctcaaat
    28741 gaccaagaaa acagcaagtc aatgtttgtc ggtcaagaat ggactaatca aacctttgta
    28801 gatttacttg gtaaccacca aggtcaagtt acaattgatg aggaaggtta tggacaattc
    28861 cctgtctcag ctagatccgt aagtgtctgg gcagtcaata ccatctaata gctcataata
    28921 accaagctag gtccaagcgg atttggcttt tttgtattca caaaaagacc tacccaaatg
    28981 gatagatctt tacttgatta caatttacct gctactgcat ccaacaattc ttggatctta
    29041 gcttggttgc ttcctcctgc catggccatg tctggtttac caccaccacg tccatcgatg
    29101 attggtgcta attctttgac aaggtttcct gcatgaaggt cttttgtctt gcttgctaca
    29161 aggacattga ctttgtcacc gatagcggca actaggacaa gaagatcaga gtagtctttt
    29221 tgtttccagt tatctgcaaa agtacgaagg gcaccggcat cggatacaga cacttgacta
    29281 gcaatgtaac gatgaccgtt gacttcctta gcatctttga agatatcgcc tgcggctgca
    29341 gctgcggctt tttctttcaa ctcagcattt tctttttgaa gttgacgaag ttgttcttga
    29401 agtccttcta ccttgtgagg tacttccttg acttgaggtg ctttcaaggt tgctgcgaca
    29461 gctttaagag catcctcttg ttcacgatag gcttcaaagg cttccttacc agtcactgcc
    29521 aagatacggc gagttcctga accgattcct tcttctttga caattttgaa gagaccaatc
    29581 tcagaagtgt tgccaacatg agtaccacca caaagttcaa tagagtagtc accgatagtc
    29641 acgacacgaa cttccttgcc gtatttctca ccaaagaggg ccatagctcc catttcttta
    29701 gcagtgtcaa tatccgtttc aactgtcttc acttcaagtg cttcccaaat tttctcgtta
    29761 acttgctgtt caatcgcacg aagttcctca gcagttactg cttggaagtg ggtaaagtca
    29821 aagcgaagga attcaacttc gttaagagat cctgcctgtg ttgcgtggtt tccaaggata
    29881 ttgtgaaggg cagcgtgaag caaatgagtc gcagtgtggt ttttcatgac acggtgacgg
    29941 cgattgctat caattgccaa ggtatattct tggttcaagg caagcggtgc aaggacttca
    30001 actgtatgaa gggcttgacc atttggggct ttctgaacat tggtcacagt agccacaatc
    30061 ttacctgact catccaagat ttgtccgtag tcagctacct gtccacccat ttcagcataa
    30121 aatgacgttt ccgcaaagat aagagaggca gttccttctg aaacagctcc tacttctgca
    30181 ttgtcagcaa cgatagctac caatttagaa gacaattggc tagtattgta gttgaagaca
    30241 ctttctacag tgatgttttg aagagtttca ttttgcatac ccattgagcc acccttgaca
    30301 gctgacgcac gcgcgcgttc ttgttgttct ttcatggctg cttcaaaacc ttcacggtct
    30361 acagtcatac cagcctcttc agcaatttct tcagtcaatt caactgggaa cccataagta
    30421 tcatagagtt tgaagacatc tgaaccagcg ataacagatt gacctttttc tttcaagtct
    30481 gctacaatgc cttgggcaaa gtgttgacct gagtgaaggg tacgggcaaa tgattcttct
    30541 tcgctcttaa cgattttctc aataaagtca cgtttctcaa gcacttctgg gtagtagctt
    30601 tccatgattt ttccaacagt tggaaccaat ttgtaaagga aaggctcgtt gattcccaat
    30661 ttttgaccat gcatagaagc acgacggaga agacgacgaa gaacataacc acgaccttca
    30721 tttcctggaa gggcaccatc accgatggca aatgaaagtg aacggatgtg gtcagcgatg
    30781 accttgaagc tcatgttgtc gccatcttgg tcataaacct taccagacaa tttctcgact
    30841 tcacggataa tcggcatgaa gaggtccgtt tcaaagttgg tcttagcccc ttggataacg
    30901 gccaccaaac gctccaaacc agcgcccgta tcaatgttct tatgtggcaa ttccttgtat
    30961 tcgctacgag gaacagcagg gtctgcgtta aattgtgaca aaacgatgtt ccagatttca
    31021 atataacggt cgttttcaat atcttctgca agcaggcgaa gaccgatatt ttctgggtca
    31081 aaggcttccc cacggtcaaa gaagatttct gtatctggtc cagaaggtcc cgcaccgatt
    31141 tcccagaagt tgtcctcaat tggaatcaag tgacttggat ccactcccac ttcaatccag
    31201 cggttgtaag aatctttatc gtctggatag taggtcatgt aaagtttttc agcagggaaa
    31261 tcaaaccatt cagggcttat caaaagctca taagcccaag tgatagcttc gtcacggaag
    31321 taatccccga tagagaagtt ccccaacatt tcaaacatgg tatggtgacg cgcagtcttc
    31381 cctacgtttt cgatgtcgtt ggtacggata gccttttggg cattggtaat acgtggattt
    31441 tcagggataa tggtcccgtc aaagtatttc ttaagggttg ctaccccaga gttgatccac
    31501 aaaagagttg ggtcatttac aggaaccaaa cttactgatg gttctactga gtgacctttg
    31561 gtcgcccaga aatcaagcca catttggcgt acttgtgcac tagatagttg tttcatattg
    31621 tctccttatt tacttgttta atgtgattgg ctttccagca tttccacata gtcaatcgcg
    31681 acacagaggg aaatgactag gtctgcataa gcgtcttcaa gaaccgttac ggtataggta
    31741 gaggtcagat ggaagagttc cttcttaatt tccgcaatca actgatcgcg atcatccagc
    31801 aatttgaaat tcaaatccca gatattgccc tcgatacgaa gacctagatt atcaaactca
    31861 tacttatctc gccaaaaggt caacttctta cgaatgacaa aactcgagcc atccagaagc
    31921 tgaatctcaa aacgaggaag caaggtcaag atttctttac tgatctgact gacttgttca
    31981 ccagccgcat catagatggt aaaagttttg ggaatcttaa aaaatgatcc ctccacctga
    32041 taggcaattt ctcccctgtc atccttgata gcgaagcgtt cgcctccaag acgaaacttt
    32101 tgtttgacaa gaaatgtttt catcaacacc tccaaaaatc aaaagacaag ctcatatcac
    32161 gaagggcgaa aaaccgcggt accaccttca ttcaatgaac ttgtcattct cttgttctta
    32221 tgcaattgta tgattgagta gcatgacttc ctagcttaga tggctcgcag caccgccatt
    32281 tctctggact aagacaagtg aaaatcaatt ctcaactttc ttattatatc gtttttttaa
    32341 tcttgcgtca actggaaatg atctccgttg aattagacca attccctaca tctctgatta
    32401 cttttccagg atatattttt tcttactgcc gtttttcttt ttatcccaaa ttttcatatt
    32461 actaaacaca gctactagaa tatttccaaa tataaaggtg cctatcaccc aatatatgga
    32521 ctcagttgtt aggtattgtc gatccaagcc atcctttaaa tggaatagta tagcagtttg
    32581 gttaacaatc ataaaggttg gccagaaact tttgttgaaa aaagtagaca ttttcattat
    32641 ttgttgccgc tttctgtaag gttaatactc aataaaaatc aaaaagcaaa ctaggaagct
    32701 agcctcaagc tgtacttgag tacggcaagg caacgctgac gtggtttgaa gagtataggc
    32761 ttagtatact actaggcaag caaataagca aataaacaac tagaatagaa aaagataggg
    32821 ctctaaaaac tgacttctat tccttaaaaa cgaaccagct tgactgattc gtcttcttac
    32881 gtttatctcc tacttccgat acattttaaa ctgtaggaag aggtcgctat atttccctgt
    32941 ccatttatgg tcaaatttct cataaatttc taggtgtttc atggtttcaa catcgggata
    33001 gaaggcctta tcttcctttg tttcctctgg gagcaattcc ttcgctggta tgtttggtgt
    33061 tgaatagccg acatactccg cattttggag agcattttca ggtttcaaca taaagttgat
    33121 aaaggcatag gctgagtctt ggtttttaac tgttttggga atgaccatat tgtcaaacca
    33181 aagattgctg gcctctgtcg gtaccacata acgtagattt tcattttttt ctaacatttg
    33241 gctggcttca ccagagaagg tcacgccgat tgcaacgtta ttctgaatca tatagccctt
    33301 catctcgtcc gcaacgatag ccttgatatt tggagtcagt ttgtagagct tatccactgt
    33361 ctcttccaac tgctgcagat ccttggagtt gaggctgtag ccgagggaat tgagtcctag
    33421 tcccagcacc tcacgcgccc catcaaagag catgatagaa ttcttatact ccggcttcca
    33481 aaggtcatcc caatgctcag gcgcttcatc taccatggtt tcgttgtaga caattcctaa
    33541 ggttccccag aagtaaggga tggagaattt attacctggg tcaaaggact ggttgagaaa
    33601 ctctggtccg atattttcga ttccttcaat ttttgaataa tcaagcggaa ccaagaggtc
    33661 ttcgtccttc atcttgttaa tcatgtattc acttggaatg gcaatatcgt aggtcgttcc
    33721 accctgcttt atcttagtgt acatggcttc gttggagtca aaagtctcgt actgaacttg
    33781 aattcctgtt tcttctgtaa actgagtcaa gagttcagga tcgatatagt ctccccagtt
    33841 atagataacc aatttttgac tatctcgact attgatttta ctatctaaat gagtcgcaat
    33901 tccccacaag acaaggataa tcgctgcaat tcctgctaaa aatgaataga tttttttcat
    33961 gcttgctcct ccttctcacg agagataaag taataaccta caactaggat aatactaaag
    34021 agaaagacta gagcagacag ggcattgatt tctaaggaaa tccccttgcg agcacgagag
    34081 taaatctcga ctgatagggt tgaaaagcca tttcctgtta caaagaaggt cacggcaaag
    34141 tcatctaacg aataggtgaa ggccatgaaa taaccagtaa tgatagacgg agtcaggtaa
    34201 ggaagcatga tttccttgaa catctgaaat tgactagctc ccaagtcata ggccgcatga
    34261 atcatgtcgc cattcatttc cttgagtcga ggcaagacca tcaagaccac gataggaatg
    34321 gagaaggcca cgtgactaga tagaacggtc aaaaagccaa gtgaaaactt gagttgggta
    34381 aagagaatca agaagctagc accaatcata acgtcaggcg caaccatgag gatattattg
    34441 agtgatagaa aggcttcttg gtatttctta cgagactggt agatgtaaat ggcaccaaaa
    34501 gtcccgataa tggtcgctat caaggctgat aggaaggcca agaaaaatgt ctgagccaaa
    34561 atcagcatga gtctcccatc tccaaacatg gtttcaaagt gagtccagct aaaacctgta
    34621 aagctattca tatcatcacc agcattaaag gcatagccaa tcaagtaaaa gataggcagg
    34681 tagaggacca gaaagaccag tcccagataa aggttggcaa attttttcat cgttctctcc
    34741 tttccttagt cacccacatg gtgatgaaca tggtcaggat gagaatcaca ccgatggttg
    34801 aacccatacc atagttgtca ttggttagaa aattctgctc aatagccgtc cccaaggtga
    34861 taacgcggtt cccaccaatc aaacgggtca gcatgaagag actcaaactt gggataaaga
    34921 ccgactgaac cccacttcgc acaccgttca tagatagagg gaagatgaca tgacggaagg
    34981 tctcccactt agttgcacca aggtcataac tagcattgat gagattatta tccatgtcgt
    35041 ctaagacatt gaaaatcggc aaaatcataa aggggagctc gatgtagctt gcgacaaaga
    35101 taaaggaaaa atcggtaaaa agcaactgtt gtgaaccaat tccgataaat tccaagaatt
    35161 ggttaataga gccattttga ccaaaaatcc cgataaaagc ataggcttta aggagcaaat
    35221 tgatccaggt aggaaggata atcagcatga gccagagttg acggtgcttg agacgggtca
    35281 aaaagagggc tgttggatag ctgataagca aggtcacaaa ggtcacaatc cctgcataaa
    35341 gcactgagtt gaaactcatt ttgaggtagg tcaagttttg tgacgcaaag taagatttat
    35401 aattttctaa actaaactgg ccttcaatgt tgaaaaagga ttgtccgaaa atcaagacca
    35461 agggtgccaa tacaaagagg gcaatccaaa gcatgtaggg cactacaaag agtttagagc
    35521 ttgttttctt catctctttc ctcctcgatc gcattgatca gacctgcttc ttgctcttcg
    35581 atttccacgt attcttcgat acgagcatcg aactcttctt cggtttcatt gagacgcatg
    35641 atgtggatgt cttctgattc aaagtccaga ccgatttcct cacccacgat ggccttacgg
    35701 gttgagtgga tcatccattc atttccaagt tcgtcatagg cgataatttc ataatgaact
    35761 ccacggaaga gctgggtgtc gaccttaact tggagtttgc cttcttcagg aagggtaatg
    35821 cgcaagtcct ctggacgaat aacgacctca acaggttcat ttggcttcat cccaccatca
    35881 accgcttcaa agcgtttgcc gttaaattcg accaagtagt cctcaatcat ggtacctggc
    35941 aagatgtttg actccccgat aaaggtggca acaaagtggt tgattggctc atcgtagatg
    36001 tccacagggg ttccagactg gacaatctcg ccatcattca taacgaaaat ccagtcactc
    36061 atggcaagag cttcttcctg atcgtgagtg acaaagacaa aggtaatgcc caatcgttgt
    36121 tgtaattcac gcaattcgta ctgcatgtct gttctcaatt tcaagtccag cgctgataaa
    36181 ggctcgtcca acaagaccac acggggttgg ttgatgatag cacgggcgat ggccacacgc
    36241 tgacgttgtc ctccagaaag tttgcggatg gaacgttttt cataaccttc caactgaacc
    36301 atcttgagaa cttccgctac acgctgctcg atttctttct tatcaatttt acgcaagcga
    36361 agtggaaagg caacattttc aaacacattc atatgtggga acaaggcata ggattggaag
    36421 acggtatgta cgtcgcgctt gttggttgga atatcattga tacgaacacc gtctagcatg
    36481 atatctcctg tcgtcgcatc cagtaaacct gcaataatgt ttaggatagt tgatttcccc
    36541 gaaccagatg cacctagaag ggtgtagaat ttcccttctt ccaactcaaa gttgatgtct
    36601 ttgagaacct tggtgttgct gtcttcaaaa actttagaga cgtttttgaa ttcgataatt
    36661 ggttttttca attggcataa attccttctt tttcatagat taaccgatcg gggctctgtc
    36721 aggtccccac tacctcttgc agggagtaaa accacctgca tacatcttcg ctaccgatag
    36781 gctttcaccc aagatccgga cttctctttc aagcgtaata cctgagtgtt ccttgacttt
    36841 ttcgataacc gattggatca agtcctcgta gtctttggcc gttccatctg cgacattgat
    36901 cataaatcct gcatgctttt ctgacacttc tacgccaccg atacgatagc ctttcaagcc
    36961 agcttctgaa attaactgac ctgcaaaatg cccgactgga cgcttaaaga ccgagccaca
    37021 agatgggtat tccaaaggtt gcttgagttc acgtaggtgc gtcaagcggt ccatttcctg
    37081 cttgataacc tgatgggttc ctggagctag ggcaaattta actgacaaga caactgcacc
    37141 agactcctga atagctgaat ggcggtaacc aaaagccaag tctttagcag acagggtttc
    37201 gatttctcca tccttggtca agaccttaca agactgcaag atgtgagcaa tctcgccacc
    37261 ataggcaccc gcattcataa agacagcacc gccaacgctt cctggaatac cacaagcaaa
    37321 ctcaaagcca gttaaactat gacggagggc aatgcgagtt gtttcaatca agttagcccc
    37381 agcttctgct tcaatggtat agccatcaac agaaacgtta ttgagcttgt cacacaagat
    37441 gacaaatcca cgaatcccac catcacgaac gatgatattg cttgcattgc caagaaccat
    37501 ccaagggata ttttcttggt tggcaaattt cacaaggcga gccaactcaa aacgatttcg
    37561 tggaaagacc aaataatcag cctctccacc tacttttgta taactatagc tatgcaaggg
    37621 ttcctgaaaa cggatatcaa ttccttctaa gatttcaagc attttttctc ttacagacat
    37681 gtcactcttc cttttccaaa attcattcca ttataccatt tttagagaca tttgacgacc
    37741 ataaaaatac cttgtttgga ttttgcataa gaaaaagagg ttcccccctt tttatgattt
    37801 tttacaaaag atttccttgg ttccataggc gaccagaacg agctccagtg ctagaatcac
    37861 ttcaaccaag actggatttg tcaaccagcc tacttggaaa agagatggtg ccagatcaaa
    37921 gaaggcatgc aagccatagg ctgttaggag ataaatccat ttcttctggc gaacagcttg
    37981 gtaaacccaa actgtcaaaa gtaattggaa accaagcgcc aagattcgct caaaaccaag
    38041 caaataaatc tgccagaccg aaagtgactg aatggttttt aacatatttt cagacagtaa
    38101 ttgcataacc tgtggattct gagtttgaac tgccgaaaga acaatgtaaa gattgagtaa
    38161 actagtaagg cctagaaaaa tcaactccaa gccaccatgc cccagtccat aggccaaggc
    38221 gtctgccttt tccaaacttc tctttttctc aaaccatttg aagaaaacaa gacgagccgt
    38281 ttcctcaaaa aatgctgcca tggctaggcc atagataata tagataagcg gatgatcttg
    38341 caagagggca atactaccgt ctttttgagg gtgcaaaatc aagatatgca ccagtttttc
    38401 caaaatctgc gaagagacaa agaaagcgac tgcacccaag cccaagacag ctagattaat
    38461 ctggtatttc tttttggcaa accaaatgct tcctatcaga aaagctagca acagcaacat
    38521 ggtaataatg atatgaatgg tcattttctt ctcctattct gccttttcaa tatctttttt
    38581 catctcgtca acattgaact tagcaaacaa gtattgacgg tcttggactg ggaaacgttg
    38641 gtccaactgg tcaactgctc ccacctcgat aatgccttcc ttgatgacaa aatccatgac
    38701 atgtccaccg aaggtcaaat catctgatat gaagtgcaga tggtagcctg ccacactgac
    38761 cccatggaaa atctcaggcg tccagaaacc aacaatagtc cccgcaacat tgtcacgact
    38821 atattccggt tgatgggttg cgacatcagc aaacttggta tcgggtgttg acttaggaat
    38881 catacgcaca tgcatatgta aaaattcccc ccgaatcttg atagagcgga aaagattttc
    38941 cccatcataa taagactcaa ttcgttcttt caattccttg tctgtcatct caaagcgctg
    39001 gcggaaaatg acctctgcct gatgcggtac cactgcagcg taaggaataa gggcatctgg
    39061 tgacacttcc acaatttctg gctggtctcc tgaccctttg gcctgataag ccttgccatc
    39121 caagacaatc aattccccat caatggaatc caaggttccc aaaccaaggt caccatgttc
    39181 tagcaattct cctactgtca tagtaccacc ataaaggcca gccatcaagg ctccaagagt
    39241 attgtattga aataatttca ctggttcctg cacgttctta tccattcact ttcttgtctg
    39301 ttattctata aatcttactc ctaagtatac cacatttgcc cctagatgtg aacgagagaa
    39361 acgttctaga cattgccaag aaggaaaaaa aagggtacaa tgtaacaaaa tcaagggagg
    39421 tctggaatga agaaacaaag caagtacaaa gaggtcgttt cctatctgaa aaatggtatc
    39481 gagtctggac gatttccgac gggtagtcgc ctgccttcta tccgtcaact gagccttgac
    39541 tttcactgca gcaaggacac cattcaacga gccctgctgg aattacggca cgaacaatac
    39601 ctctatgcca agcctcagag tggctactat gtattagaac aagggcaaca tcaagaccta
    39661 gaaatcgagg ttaccgacga acatgccagt gcctatgacg atttccgact ctgtgtcaat
    39721 gaaaccttga ttggccgaga aaactacctc ttcaactact atgacaatca agaaggatta
    39781 gaagacctaa gacagtccat tcacaaactc ctctttgagc aagctctcta ctgcaaggct
    39841 aaccaactag tactgacttc tggaacccaa caagccttat ttatcctctc tcaaatatcc
    39901 tttcctagac aagccaagga aatcttggtg gaacagccaa cctaccatcg gatgaatcgc
    39961 ctcttgattg cacaggggct ggactatcaa acgattgaac gaggcattga tgggattgac
    40021 ttggaggagc tggaaggcca cttcaaaaca ggaaaaatta aatttttcta caccattccc
    40081 cgatttcact atcctctggg acattcctat tctgagcaag acaaacgatc tattcttaac
    40141 ttagctgcca agtatgatgt ctatatcgta gaggacgatt atctgggtga tttggactcc
    40201 aagaagggcc aaaccttcca ctatcttgat acagaggagc atgtcattta tatcaagtcc
    40261 ttctcgacca gcctttttcc tgcccttcgt attacagcac tcattcttcc aaatgctatc
    40321 aaagaagcat ttgtggccta caaaaatatc ctagactacg acagcaacct cattatgcaa
    40381 aaggccctgt cactctatat tgacagtcaa ttgtttgaaa aaaatcgttt ggctcgcttg
    40441 accaatcatg aatcttacca aaaacaaatc gaggaaagga taactaaaac accttgtccc
    40501 cttcctcatt atcccctaca cgatggttta ttgctagacc tgagacagta tcctaaaatc
    40561 gccagtctca aacacagtca actgggcttg gacttctttg aagaggccta tttgagcacc
    40621 tgtccttatc aatttgccaa ggtgtcccta gacaatctgg aaaatgtttt aaactattta
    40681 aaagcagaat tggaatgaca tccaactctg ctttttctta ttcttcaact tcagttagac
    40741 ttgctgcttt ttcaagatag ctttggtaag ttccttcatc cttaagtttt tggatgacct
    40801 tgtctaccac ttctttcaaa tcatcactat tttttctaag agcaacggca ttggcgtcgc
    40861 cgtccttcat cttcaagctg acagttgcga cagctaagcc agcgttttta gcagcataac
    40921 taagtgcaac aggctcatcc atatgaacag catctatttt tccagcctgc aattcattga
    40981 ctgcttcacc catattagtt agggaagtta attgagcttt tggcaattgt tccttgacca
    41041 ttgattctgg aacagtccct ttttgggctg caatattagc actttctagg ctagttaaat
    41101 ccttgtattt ttccacatca gccttacgaa ccaagaaact aatcttgttt tcatagtatg
    41161 ggattgaaaa atcaaagact tcttttctct cgtcagtagc actaattcct gcaactgcta
    41221 ggtcagcctt accagtttga agactggtca aaacattgtc aaaactcatg cttaagattt
    41281 ccaacttaac cccaagttca tcagcgatag cctgagccat gtcgatgtct gcaccgacta
    41341 cctggttctt tccatcaacc aatgattgaa attcaaaggg tgcatagtca ggactggttg
    41401 ccacaactaa tttccccttt tgcttaatgg cctcaacagc tgactgagaa ccattagaac
    41461 ctgactggca agctactaag aagaaacttg caagaaaatt acataaaaca aatatccatt
    41521 tttttgattt cataaataaa caacctttct gttaattttg tataattata acgatatcca
    41581 agttacttgt caagtgtttt ttaaattttt atctcaaaaa tattttttcg ttcaaaaaaa
    41641 ggagccatca gttgatttca agctcctttt tatacagaat taaactattt tatagttcga
    41701 caatcttacc tgtttcaaag tagacaaccc attcacagat atttttagca tagtcaccga
    41761 tacgctccaa gtaggaaata acttggaaat aatcacgacc cgtaacaatg gcttctggat
    41821 ttttcttaat ctcttcagtc gcaaggtcac ggatagtttc aaaatagtgg ttaatttgct
    41881 catccatgga ggccacccgg tatgcgtcgt caacagaacc attaagataa agatcaagtg
    41941 ctgcttccac aacgctttta acttcacgtc ccattttttt aatttcttcc tctacagctg
    42001 ggatgcgttc ttcccccttc atacggatgg ttgcctgggc aatggctaca gcgtgatccc
    42061 ccatacgctc cacatctgat acagccttaa ggacagtcaa gactgtacgc aaatcttgag
    42121 agactggttg ttggagtgcg atcatttcaa atgatttctt ttccagtttc acttcgtatt
    42181 catttacttc tgcatcatct tcgatgacct cttttgccag gtcacggtca tgcgtgacaa
    42241 aagcacgtac cgtacgattg atttgtgaga gcacttcttg tcccatagcg tagaactggt
    42301 tatgtaattt ctctaaatct tcttcaaatt gagatcgtaa catctttcat ctccttatcc
    42361 aaattttcct gtaatatagt cttccgtttc cttgtgttgg ggatcaagga acatctgctt
    42421 ggtatcatta aattcaatca aatctccatc taggaaaaat cctgtcttat cagagatacg
    42481 tgaagcttgc tgcatggaac gggttaccag aagcatggtg tacttgtctt ttagaccata
    42541 caaggtttcc tcaattttac cagctgaaat cggatccaaa gccgaagttg gctcatccaa
    42601 gaggatgatt ttaggactag ttgccaagac acgggccacg cagacacgct gctgttgacc
    42661 acctgacaat ccaatagctg aatcatatag acgatccttg acctcatccc agatagaggc
    42721 accttgcaag gctttttcta cggcttcatc cagaacctgc ttatccttaa ttccattgat
    42781 acgaagcccg tagacaacat tctcatagat agtcataggg aaaggattag gttgttggaa
    42841 aaccattccg atttccttac gtaattcaac cgtatctgta cgcggactgt agatgttgtg
    42901 accattgtac accacggatc cagttgtggt cacctctgga ttgagatctc ccatgcggtt
    42961 gagagacttg aggagggttg acttccctga tccagatgga ccaatcaagg ctgtaatttc
    43021 cttaggttgg aaagataggg aaacactatt caaagccttc tttttattat aatatacgga
    43081 caggtctgat acctgtaaaa tcgcatctgt catacggttt cctttctaac caaagtgacc
    43141 agatacatag tcattggtgg actgtagctt ggcattttgg aaaatagttg cagtcttgtc
    43201 atactcaatc aaatcaccca agtaaaagaa gcctgtatag tcacttgcac gagcagcctg
    43261 ctgcatatta tgcgttacaa tgatgatggt aaagtttttc ttgagctcaa acatggtctc
    43321 ttctagttgc atggtcgcaa tcggatccaa ggctgaggct ggctcatcca ttaagaggat
    43381 atctggctta acagagatgg cacgagcgat acagagacgt tgttgctgac cacctgataa
    43441 ggtcaaggct gacttgtgga gatcgtcttt aacctgatcc cagagggcag cctgacgaag
    43501 ggaggtttct acgatttcat ctaggacttg cttatcctta actccagcac gttcatgcgc
    43561 aaaggtaata ttacggtaaa ttgacttagc aaatggattg gggcgttgaa aaaccattcc
    43621 aatgtgttta cgcatttcat aaacgttgat ttctggacgg ttgacatcaa ttccacgata
    43681 gagaatctgc ccagttactt tagcaatatc aatagtatca ttcatgcgat tgagactgcg
    43741 taagtaggta gatttccccg atcccgacgg accaatcaaa gctgtaattt tatttctttc
    43801 aaattgcata tcaatcccct taatggattc atttttacca tagtaaacat ggacatcctt
    43861 agtagaaagg gctacttttt cttcaggaaa ggtaaggata tgcttctcat cccagttata
    43921 tgttgacatg gcttctcctt taggcagcgg ttaatttctt gtgtagatag cttccgaact
    43981 tacgagctcc aaagttaaaa atcaggataa agatcaggag cacagcggca gaacctgctg
    44041 atacaatggt tccatctgga atagtgcctt cactattgac tttccagata tggacagcca
    44101 aggtttctgc ttgacggaag atagagatgg ggctagtcac actgaggata ttccagttag
    44161 accagtcaag agctggcgcc gattgccctg ctgtatagat cagagctgca gcttcgccaa
    44221 agatacgacc agatgccaag acgacacccg ttacaatacc tggaagcgct tctggaataa
    44281 caacatgaac cactgtctcc cagcgagaaa tcccaagagc cagaccagcc tcacgttggg
    44341 tatggtgaac gtgtttcaaa ctatcctcta cattacgcgt catctgaggc aagttaaaga
    44401 ctgtcaaggc caaggcacct gaaatgattg aaaatccata ctcaaactgg actacaaaga
    44461 tcaagtaacc aaagagaccc accaccactg atggtaaaga ggacaagatt tcaatacaag
    44521 tccgcacaaa gttggtaaca ggaccttttt tagcatattc agccaagtaa atcccagctc
    44581 ccatagaaag aggtacagaa ataatcaagg taatgaccaa taggaaaaag gaattgtaaa
    44641 gctgaatgcc aatcccacca cctgcttgaa aagcagaaga ccttccagtc aagaaagacc
    44701 aagagatatg gggcaagccc cgaaccaaga tatagagaat caaggaagcc aagattgtca
    44761 caatgatgct agcaatcgta tagaggacag ctgttgcaag tttatctaat ttcttagcgc
    44821 gcataatttt tctttcctct ttctttcgta atcaatttaa tcacactgtt aaaaactaaa
    44881 ctcatcaaga gcagtaccaa ggccagtgac cagagaacat tattatttac agttcccatg
    44941 acagtgttcc caattcccat agttaatata gaagttaaag ttgcagctgg tgtggtcaag
    45001 gaagttggga taacagctga gtttccgaca accatctgga tagctaaagc ctcaccaaag
    45061 gcacgcgcca tcccaaagac cactgcagtg aaaataccag aacgggccgc cttcaagatc
    45121 acacgccaga tagtctgcca gcgagtggct cccatagcga aacttgcctc acgataataa
    45181 cgaggaaccg cacgcaagct atccgttgtc ataaaggtta cggtcggcaa aatcatgaca
    45241 aagaggacgg aaatccctga caaaatccca aaaccagtcc caccaaagac actgcgaaca
    45301 aagggaacga cgacttgcaa gccaataaat ccgtacacta ctgaaggaat cccaaccagg
    45361 agttcaatag ctggttgcaa aatcttcgcc ccttttggtg atacttcggt cataaaaact
    45421 gctgcaccaa tagcaaaggg tgttgcgata agggctgaga gaatggtaac gataaaggaa
    45481 cccaaaatca taggaagggc accaaattct ttactagaag gattccaagt tcctcccaaa
    45541 agaaagtcaa agatattcac accattgaca aagaaggtcg acaagccttt ttgcgctacg
    45601 aaaaccaaaa tcatggccac aaggatgact atcaaagaaa gacaggcaaa ggtcaaacct
    45661 tttcctaatt tctccagacg agaattcttt gatggaagca acattttctt agctaattct
    45721 tcttgattca ttattgtctc ccttccaaca ctgtcacagt tccggcagca tctttttcaa
    45781 ccttcatttc cttaatcgga atatacttca atcctttgac aatcccttct tgggtctcat
    45841 ccgagagaac aaaattgaga aattctgcag ctaactcatt gggctgcccc aatgtataca
    45901 tatgctcata agaccacaag ggccaattat tgctacttat attttctgga cttaagtcat
    45961 agccattcaa cttcatgctt ttgaccgaat catctatata ggtaagagat aaataagaga
    46021 tagctcctgg actttttgat acgattgatt ttaccgctcc atttgaatcc tgctcctgac
    46081 tttgcatggc agactgacct tccataatga cagtatcaaa ggtagcacga gagccagagc
    46141 cggctgcccg attgataaca gagatgggta agtccttacc accaacctct ttccaattgg
    46201 ttacctcacc tatgaagatt tgacgaagtt gctctgtcgt taggttatca acatcaacct
    46261 ccttattgac aatcagagcc aagccagcta ccgcgacctt gtggtcaaca agagcagaag
    46321 catcaattcc gtctttttcc tcagcaaata catctgagtt tcctatatca actgccccag
    46381 actgaacctg ggacaagcct gtaccagaac ctcccccttg gacattgacc gtttttccaa
    46441 catggatcgt gccaaattca tctgccgcta cttcaaccaa gggttgcaag gcagttgagc
    46501 caacagccgt tatggattct ccacgatcaa tccagctagc acagcctact aaacaagccg
    46561 tcagccaaaa agcgataaga gacagagcaa gcttttttct ttttttcact gtttttctcc
    46621 tcgaaaataa ttatgaatac tgtgaatttt ttaagtagtt ctttatgagt tgacgcatga
    46681 attcttacca aatttctgcg caattgatta tttatataat ataggctata ttactctttc
    46741 ctaacctcct tttttcatat gtggataaaa tctcttgtct atcccttccc ccattgtcac
    46801 ccattatagt catttcgtgt ctctttttcc cctttttaat gcaagggaaa ttactctcct
    46861 tagatgataa tccaaaagct agaaaggtat ctcaaatctc tctactctcc cagactagtt
    46921 tacaactaaa aggaaaagat tctattttat gagaaatcta gtttacaagc ggtaagaacg
    46981 ctaataacta aacttcttgt actctttgaa aatctcttca aagcagtgtt ttgagctatc
    47041 tatggctagc ttcctagttt gctctttgat tttcatcgag tagtaaaact acatgtgatg
    47101 gcaatcaaga tatcaagaat catcctacta aaaaaatcca tactttcact ataacataga
    47161 ataagatatt tgactagcat tttcatttga atctgaggcc ttttggaaaa taatttttca
    47221 aaacatttcc agtaaccttt gcaaagccca agccattgcc tttaaccaaa acttggtacc
    47281 aaccatttgg cagactttct gccagctgaa cggtttctcc agccgcatac ttgacaaact
    47341 cttcttggcc aatttcaacc gactgttcga cctgactcgg tttcaaggct aaaccaagag
    47401 cgaaactggg ctcaaagcgt ttcttcttaa aagtacccag atgcagtcca ttgcgagcaa
    47461 tcttgagctt ccctaaatct ggcaaaagtt ctggcaagag ataaagctgg tctccaaaaa
    47521 tctgcaagat acccggtaga ttgaccttca aatggttttg ggcaaattcc tgccacaagg
    47581 caacttgttc acggctgagg ttactcttac ttgccttaaa tttaggagct ggattgttac
    47641 ccttaaactg tagatgggca acaaactgac cctctccctt aaactgatga gggtacatcc
    47701 gagccgtttc tggcaggtca ataccagcta ccattccatt gatatgctct actggcaaca
    47761 agtcaaaatc atactcttcc agcaaccaat tgacaatctc ttcgttttcc tcgggtgccc
    47821 aggtacaggt cgaataaacc agacgaccac cttcagctaa catggtcact gcatcctcca
    47881 gaatttctct ttgcaagcta gcacattgac tcggataatc taagctccaa tagtccatag
    47941 catcaggttg cttacgaaac attccttcac cagagcaagg ggcatcaaga acgattaagt
    48001 caaaatagcc tttaaagacc ttgaccaagc ggtcggcaga ttcattggtc accacgacat
    48061 ttgtcgctcc aaaacgctcc atgttttcaa ccaaaatctt agcccgtttg cttgaaattt
    48121 cattggaaac aagtagcccc tcccctgcta gataggctgc cagttgagtt gatttgcccc
    48181 ccggtgcagc agccaagtcc aagaccttca taccaggact gggttgggct acttgagcca
    48241 ccatttgagc agcaggttct tgcgaataaa ctaaacctgt agcatgctca ggcgatttcc
    48301 ctgaaacctt cccatagtgg ccccaagggg tttgagtaat ggcatcagaa aaggaaagtt
    48361 gctcttcttt taagggattg acccgaaagg ccgaaaccgc ttcctcctca aaagaggcaa
    48421 gaaaatctct tgcctcatct cctagtattt ctttatattt ttcaacaaat ccttctggaa
    48481 atttcattta agttcttttc ctttcgtaaa tataggactg aatttcctcc tgcatctcaa
    48541 gaggcaccat catgaccggc tgtctggttt gaaaatcagg agcttcacca aaaagggtca
    48601 caacccgata gcccagactt tcccctaaaa tactagctgc ggcataatcc catggttgca
    48661 gataggtgag ataggtcaac aaacgccctg acaaaatctt ggcaaaacta atggccgcac
    48721 ttccatagac acgaacacca agaaccgctc ggctcaaatc agccagcccc cattcattgg
    48781 tttccagcat accactattc cctgcaatga gaaaatctcc aagtggttta gttttaaaag
    48841 aagctagggg cctatcattt agacaaactg gaaattcccc accaccgtgg taacaatccc
    48901 ctttgaccac atcataaatc agaccaaact gtccctgacc attttcaaaa taagccatca
    48961 taacagcaaa atcttcctgc tgggctacaa aattattggt accatcaatg ggatcaatga
    49021 cccaaacctt gccctcttga accgaggctc gcagacaacc ttcttcagca caaatcttat
    49081 cctcaggata acgggacaaa atctcaccaa ccaagagttc ctgaacttct ttgtccagtc
    49141 tggtcaccaa atctgttgga gaggacttgg tttcaacacg caagtcttcc tgcatatggt
    49201 caagaatgta ctgacctgct ttcttaacaa gctctttagc aaattcaaat ttacttttca
    49261 agagaaatct ttcctttccc tttttctttg gcagcctgaa ctgctcggta aagtgaatag
    49321 ccactaaccg tttcaaattc tcgtcccaaa cgtttctctt cgctcttgct tggcacgacc
    49381 gctttgaatc ccttatagga gtccagtaac tttttagcct ctactttgcc ttcataggca
    49441 gcttcaacat cattaaaaaa agaaagcact gaagcaagtt cttcagtgct ccacgacaaa
    49501 tctagtgggt aactatactg tttgttcatt aactaatacc agctctcatt cttgcttctt
    49561 ttagttcttg cttacgataa ctacgaggga gaaaagcacg aatctcatct tcattaaaac
    49621 cgatttgcat acgcttggca tcaataataa ttggacgacg caaaagacta ggatactgct
    49681 caatcaaatg aagcaattcc gataccgaaa tactctctac atcaatattc aatttttgaa
    49741 aaatttttga acgagttgaa atgatgtcat cagtaccatt ttcggtcaag gaaaggatgt
    49801 gttgcaattc ttttcttgtt aaaggactgg tcataatatt gtgttccaca aagggaacct
    49861 tatgtttttc taaccaggtc ttagccttac gacatgatgt acagctcggt gatagaaata
    49921 gtgtaatcat gcttttctct tcttatctat actttgctac ttctattata caaaaaaata
    49981 aggcgcttga ctagggattt ttagaaaaaa agcctatttt ttcaggaaaa ataggctgtt
    50041 tgcgaacgat tgacacaatt ggatttggtt aattcactct taacgatggt tttaaacgat
    50101 atatatattt atatatgtaa attaaaaaca tctttccttt cacttcctac gacttttcag
    50161 acacagatag ccaaagaagc tttcatagag ggcaaaaaag aggaggaagg catgaagaaa
    50221 gaaggtctct ggcaaaatca taataacagg atccttggct ggatcaaaaa gccaggtatc
    50281 atctcccaca aagagaattt gatggaaaag agtaaagaat tggtcaaaac caatcaaaac
    50341 tcccccaagt ccaatcatca caggtaagac tactagagcc aggagacttt ttcgataaag
    50401 agacaaaaag tcctttttca caatcctatt gacaaagaca tagaaacttg gcagtgtcac
    50461 tagagctact agctgaacca aatgaaagag attcttgacc actgcgaaat ggtgcaaacc
    50521 agctgctgac gaacgaaaat caggcatctg taagacctga ctaaaaggat tggtcagata
    50581 attcatcaag atatgaaaat tgtattgaat ggtttctggt tttagataga ctcgattcgt
    50641 taagtttagc cactgaatct ccataggata gaaaatccaa gccagataaa tggtcagaag
    50701 gattgagagg gagaggagaa agagcataga gccccaaaag gtcaatttag ttttcatcaa
    50761 aatcccactc cgcaaggcta gaaaccacat gtgtcggtgc gattggcagg ccagctactt
    50821 cttctgcctt ggtaaaacct gtcgtcacca agagcgttgg aatgccattg tcaatcccag
    50881 cccggatatc agtcaaataa ttgtccccaa ccatgattaa ctcttcacgt tccaaaccta
    50941 agtgctcaac tgccttgtcc ataatgatgg cattgggttt tccgatataa accggcttca
    51001 ctcgtgtcgc tacttcaagc agcgtaatca gtgagccagc acctggcaaa agaccacgtt
    51061 ccgtcgggat gttgaggtca ggattggttc cgataaaatg ggcacccttt tgaatagcaa
    51121 gagttgctgt ggcaaatttt tcatagtcga cttgccaatc cagaccaact accacgtagg
    51181 caggtttttc cttgtcttcc acataaccag ccgccttgat ggcttccttg agtcctgctt
    51241 ctccgacaac atagacggtc ttttcaagcc ccaaatcatt catatagtcg atggttgcca
    51301 aagtcgctgt gtagacagtc gataggggcg tatcgatatt aaaattctga gccaacatct
    51361 ccttaacact ctctggagtg cgggttgtat tgttggttac aaagagatag ggaatgtccc
    51421 gcttttgcaa ttcatgaaca aaagtctctc cagcagggat ttggtctttc cccttataaa
    51481 tggttccgtc taaatcaatt aaatagcctt tatatttcat ctatttctcc ctaagccttt
    51541 tttatttctt gccaagtaat gattgcttgg gcattgataa ccccatcact tgtaatttca
    51601 tgcttgcttt ccagtccagt ccgttcaaca gccgatgtaa tcaccccacc tggtcgaact
    51661 tccttgacat acttgaggtt gattttcttg ggaatatagt gggtcaaaaa atccgctccc
    51721 atgacctcaa aaatccagtc taagtattta ctgttattga catgaccatt catatccaag
    51781 tcgtaaaaac gaacatggta atccttgctg atcgactctt ccaaggactc atacttcggt
    51841 ccacggataa gttttttatc aaaatcagac tggtaaggag ccacaatctc aggttcaaca
    51901 gcatggactt ttcgactgtc gcggtccatg agaacaaagg tcgccatcat atggatgagc
    51961 tcctgccccg cttcattata aatagtaaag cgacggtagc aaaaaagtcg attgtagctc
    52021 aaggcttccg tttcgatggt aatttcttcc gcaaaacgag gcaaacgaac cacctcaata
    52081 tcatattcta cgataatcca gaccagatta tagtcttcca aaatggcctt atcactaact
    52141 cccagttcaa tcgactgcat ccctgaaact tgcagtgaca gcaaaattac atctggaagt
    52201 ttgatatgac cgttcatatc agccatatca aaaggaattt tcattttcat ttgataagtt
    52261 aagcccatga tcctactcca aaataaatcg ttccgctaca gtatctccca aaaagagacc
    52321 tctctttgtc atgcgaacgt ggtcaccctc aatctgcatg aggccttgtt gaaccaaatc
    52381 tctgacaatt tctccataaa gtccagcaaa agactgtcca aatttttcct caaatcgcgc
    52441 catggaaacc ccggatttct tgcggagtcc caagaacatt tcttcttcca tttgctcctt
    52501 ttgactcagg tgatcttctg taatacaagc attgccttcc tcaaccgcac tgagataatg
    52561 acgaatggga ccatgatttt tatagcgtac tccattgaca taaccagatg cccctgcacc
    52621 aataccatag tattcagcat tgtcccagta catgagattg tgacgacttt caaagccggg
    52681 tttggagaaa ttagaaatct cataatgctc aaaacccgct cgctccagct ctgcaatgat
    52741 gtactcaaac atctccgctt ctagttcctc cttaggcaga ggcaatttcc cacgtcgcat
    52801 ccgattcata aagaccgtat ggttttctaa aatcaaacta tacaaactca tgtggggaat
    52861 atccagtcca atggctttag ccacattttc ctttacttgc tccatggtct gaccaggcag
    52921 agcataaatc aaatcaatgg agatgttgtc aaaaccagcc agtttcaggc gatcgatatt
    52981 ttcataaata tccttctcca aatgactgcg cccaatcttt ttcaacatct tatcatcaaa
    53041 ggtctggaca cctagcgaaa cacgattgac agccgaattt ttcaaaacag ctatcttatc
    53101 cgcatccaaa tcgcctggat tggcttcaat ggtcaactct tctaagacag acaagtccaa
    53161 gtttttagtc aagccattca gtaaaacctc cagttgcgga gccgacaggg ctgtcggtgt
    53221 tccaccaccg atataaaggg ttgacaactt ttcaatatca taagaacgaa actcttccag
    53281 cagatgctct aaatagctgt cgactggctg atttttgatg aagacctttg aaaaatcaca
    53341 ataataacaa atctgggtac aaaatgggat gtgcacatag gctgacgttg gttttttctg
    53401 catagtaatt attataccac aaagactaga ttccagataa aaatcaccat ccccagatac
    53461 atagtccgtc cggagatggt gatggtttat tcttctgtta tatcaatcac aatctcttct
    53521 gagtcatcaa gagcttcggc tttttcttgc cattgctcct tgagattatt taattgattt
    53581 tttgatgctt ctgtcgcttg aaaagcatag gatttagctt gagcaagtat actgtccaca
    53641 gtgatttcac ctgactcaac ctgttctttt gttttcagaa caaaatctgt agcctgctcc
    53701 ttaacttctg tcagtttttc acagacttgc tccttggcat actccggatc ttctctcaaa
    53761 tcatctagaa aatcttgagc ctgactgcaa acttgtttgc ccttatcact tgttaaaaac
    53821 aaggcaagag ctgcacctga aacggttcct aaaaggattg aggataattt acccataagg
    53881 attctccttt tttatttttt gaaaaattta cttgcaagac gaagagctga cagacttgca
    53941 ccagtcttga gtgtttttga accagctgat gaagctttct tgctcaagac acgcgcatgg
    54001 tcattgaggt ctgaaacaga tagagataaa tctgcaacag cactgaagag tggatcaatc
    54061 gtagccacct tgacattgat atcatctgcc aagacattga ccttagccaa caactcattg
    54121 gtgtgatgca aggtcacatc cacatctgaa gtcaaggttt taatcgtctt ttctgtttca
    54181 tcgatgacac gaccaagctt ttgtacagta atgatcagat agaccaaaaa gacaatcaaa
    54241 gctagggcaa caagaatata tgcaacttct aacatttagt tttcctcctc tgtaatatag
    54301 taaggggcct tctttcgatt ttgataaata acgatcatta taccgagacc gataaggaca
    54361 actgacagcc attgggacac tcgaaggccg aagaacatga gactatctgt tcgcatacct
    54421 tcgatgacca tacgaccgaa accataccaa atcaagtaaa aggccgtgat atgacctcgt
    54481 ctgagactct tccatttccg tctaaaaatc agaatcaagg caaagccaag cagattccat
    54541 agagactcat aaaggaaagt cggttgacgg tagctcccct caatatacat ctggtcacgg
    54601 ataaagccag gtagataatc cagattatcc actgttgcac cataagcttc ttggttaaag
    54661 aaattacccc aacgccccaa actttgagca atcataacgc taggcgccgc aatatctaga
    54721 aaatcccaag tattgatgag tttacggtca gcaaagatat agagcacaag agccccagtt
    54781 atcaaaccac cgtaaatggc caaaccacca ttccaaatgg caaaaatctc tcctaaattc
    54841 tgactatagt aatcaaatcg gaaaataaca tagtagagac gagctcctaa aatagccaag
    54901 ggaaaggcta ctaagataaa atctaaaata tcgtctggta tgatcttctt tctaggtgct
    54961 tctttcatgg tcaaataaac cgcaagaatc aagcctgtca caatacataa ggcataccaa
    55021 cgaatggcta ggggtcctag ttgaatagca attggatcaa gcattttgca cctcatttcg
    55081 agcgatgaga cttgtcagtc gttcgtcgaa caaacgggtc gcatcaaagc ccatttcctt
    55141 ggcacgataa ttcatggcag ctgcctcaat cacaacagag atattacgac ctgttttaac
    55201 tggaatacga atacgaggaa tggctacgcc agaaacttca agttcctctg cattgtttcc
    55261 aagacgatca aaggtcttat gcgtatcgta attttccaaa tagacagcaa gctgaacctg
    55321 tgaagaatcc ttgacagcac tcgcaccgta gagactcata acatcgataa taccaacccc
    55381 acgaatttca atcaagtgtt tcaaaatttc agctggttca ccccagagag taatctcatc
    55441 cttggcaaag atatcgacac ggtcatctgc taccaaacgg tgaccacgtt tgacaagctc
    55501 aagacctgtc tcgctcttac caattccact atctccctga atcaagacgc ccatcccata
    55561 aatatccatc aagacaccgt gcacactggt acgttctgcc aaacgagaat ccagatagct
    55621 agataactct ccagataaac gactggtagc tgcacggctg gttaaaatag caatcttaca
    55681 ttctctagca gcctttaaca tctcctctgg aaccaccaaa ccacgggcaa caatgactgc
    55741 tggtgtctca gatagaaaca tttttttcaa aacttcataa cggctgttgg aaggcatgct
    55801 gatcagataa gaccactcct tcatccccaa aagttgaatc cgctctggtg tgtagtagtc
    55861 aaaatagcct gtcatttcaa gaccaggtcg cgtaatatcc gctgtattga tttccttttc
    55921 aagcaactct ggttcaccat agacaatatc tagtctaagc ttttcaatca cttcttttac
    55981 taaaaccgac atcatttcct ccttcaaatg agttcttctc tctattatat caaattgtag
    56041 gaggaagttt cagatttttg caggctttgg agtatttatt taaaagaaaa aggactagat
    56101 ttctctagcc tttcattcca attagaattt tttacgttta cgagctactt ctgatttacg
    56161 tttacgtttt acagaaggtt tttcatagaa ttcacgtttg cgtgtttctt gaagagtacc
    56221 agctttagta accgcacgtt tgaaacggcg aagtgcgtcg tcaagagatt cattcttacg
    56281 tactactgtt ttagacattt ttttcactcc cttcaagttc gatatctatt tcattctaca
    56341 cgtaaaagga ataattgtca agcaaaaatg ctgtttaatt ttgatttttt cttccattta
    56401 tacaagagtt gaaagcgttc aatagaacat tgctttttta tttttcgagt aagctaagcg
    56461 cttcagcatc tgcgatgatg gttacatcag ggtgattttg gaggctactt gcaggtaggt
    56521 tctcagtcac tgggccagat actgttccgg caatggcttc tgctttcgac tcaccgtaag
    56581 caaaaagaat aatagacttg gcatccaaaa tgtttttaat ccccattgaa atagcttggg
    56641 ttgggacgtc ttcaatcttg gcaaagaagc gtgcattggc ttcgatagta gactggtcaa
    56701 gttctactag atgcgtttga ctgtcaaatg gagtaccagg ctcattaaag ccgatatgcc
    56761 cattgcgacc gattcccaag atttggaggt caactggatg gtcagccaaa atttggttgt
    56821 agcgttcaac ttcagcttca gcattgtcct taacaccacg aggcaagaaa ctttctttaa
    56881 atggtttttg gttgaacaag ttttcttgca tgaagtaacg ataagactgt ggattgtccc
    56941 catcaaggcc cacatactca tcaaggttga cactggttag atttgaaaaa tcaaggtcac
    57001 tctcaacaat ttccttgtaa aattcaagtg ggctacttcc tgtcgcaagt cctagagttt
    57061 gagctccatt agccaatttt tccttcaaaa tctcaaaagc aacttttcca ccttgaactt
    57121 ggttttcaac tttaataact ttcatctttt catcctccat ttctgtctat atttattata
    57181 tggtatagac caatttttgt caagtgaaaa cgatttaatt tctaaaaaaa gagcgtccaa
    57241 acttgaaacg tgttataatg gataggatta gaacttagaa agaatgaaca gatatatgaa
    57301 tacagctgat tttgatttcc acttgccaga ggaattgatt gcccaaacgc cccttgaaaa
    57361 acgtgatgcc tccaaactcc tcatcgtcaa ccgtgagaca ggagaaatgc aagataaaca
    57421 cttccactct attattaata tgctggaacc tggtgatgcc cttgtcatga acgacacccg
    57481 agttctccct gcccgcctct atggtcaaaa agtggagaca ggaggtcatg tggaacttct
    57541 cctccttaag aacactagtg gagacgagtg ggaagttctg gctaaacctg ccaaacgcct
    57601 caaggtcggt actcgtatca gctttggtga tggccgcctc agcgctgtcg ttacagaaga
    57661 attgacccac gggggacgca ttgtccgctt tgaataccaa ggaattttcc tagaagtctt
    57721 ggaaagtctg ggagaaatgc ctctgccacc ttatatccac gaaaaattag atgaccgtga
    57781 acgttatcaa accgtctacg ccaaggaaag cggctctgct gcagcaccga ctgctggtct
    57841 tcacttcacc aaagaactgc tggcagaaat ccaagctaag ggtgttcatc tagtctatct
    57901 gactctccat gtcggactcg gaacctttag acctgtttct gtggataatc tggacgaaca
    57961 cgaaatgcat tcagagttct atcaactttc tgaggaagct gctgccaccc ttcgctctgt
    58021 caaagaaaat ggtggtcgcg tcatcgctgt cggaaccact tctatccgca ccttggaaac
    58081 tattggttcc aagtttgatg ggcaaatcca agcagattct ggttggacca atatctttat
    58141 caaacctggg tatgagtgga aggtcgtgga tgccttctca accaacttcc atctgccaaa
    58201 atcaactctg gtcatgttgg tttctgcctt tgcaggccgt gaattagtct tagatgccta
    58261 ccaccatgcc atccaagaac actaccgctt cttcagtttt ggtgactcca tgtttattta
    58321 ttgagaaaga atttctctaa atcttctaat accaataaat cgctaagata ttatttcaaa
    58381 gaacatctac aattgaaact ctagctagct gtagaagacg cctagtacat tgaaattaaa
    58441 atgcttcccc ctagcttcga aaatattgcc atagattgcg ttgactctcc aaattgattc
    58501 atctatattt tatttcagct tcctatattt tcttcgctgt ttgtaaatca aaatgcaaga
    58561 cacatgagta gcaccatatt tgttactctt atctgtcctc tcaagagact attatgagtt
    58621 atttcagaat cattcactac tttgaccctg actctcctta gtctcaaaat caaagactta
    58681 tactcttcaa aaatctcttc aaactgcgtc aacgtcacct tggattatat atgtgactga
    58741 cttcgtcagt tctatctaca acctcaaagc agtactttga gcaacctgcg actagttttc
    58801 tagtttgctc tttgattttc attgagtatt aaacaaaaag tgaacaaatc tgaattctaa
    58861 tgtacagaag actaggcttg ttcacttttt tatagtcgct ataagatgac cttatctata
    58921 gctttttata tataattata tataattata tattcagaca tactattatc aattttgtcg
    58981 cagggaggaa tctgttaacg cacccattca ccattatcat tgactctata gccatctata
    59041 cttgtattga ccgctaactc acccgatgca tttacataat accatttacc accaacttgg
    59101 aaccattgat tgactttcat agaaccgttg ctgttgaggt agtaccatga accattaact
    59161 tgtacccaac ctgttgccat ggaaccatca gtattataaa aataccacat accattttct
    59221 tgtttccagt ctgttgttgg agcaactgct ttagctggtt ctactgctac atctgttcct
    59281 tggttagatg taacagatac aggatacgaa ggaatagatg attgctcagg aacaacaact
    59341 ttttcaggtt ctctcgtccc tctccttata cgtcttttta ccatctcttt agtaatttga
    59401 cgagaagtag tttcttcaat tgttccatca cgttcatcta cagtatagat tgtagtaaga
    59461 gtaatttacc aatttctcct acttcttcta cttcttgact tttatcaaga gttgggtcat
    59521 cgagatattc tgtttcgatt ggaatttctt ggacaagaac ttggggcttg gttccttttt
    59581 taacaactct tgtttgagag tcttcttttt gacttaaagt actctcagtt acttgtccac
    59641 tctttccatc tacatcataa gttatcgttg taactgtttt cccattcttt cctagagtaa
    59701 tctcttgctc ctgtcctgca gaaaggtcat tgtctgcttc atatttagta gcacatggaa
    59761 caagaacttc ttcaaccttg cttttagctg gaactttgat aactgtatcc gtggcttgtt
    59821 ttctatcaac agtaacctgt tcggtaacat gaccagtctc tggattaaca tcgtaggtcc
    59881 ttgtcgtagt tacatagcca tcctctccat caattgtaac aggattttca ctacggtctt
    59941 ttgtttcatc tttttcataa cgaattcgcg tacttgaaat tttcttggtt actaccttag
    60001 gtttagtcgc tacttttaca ataatacccc cattgtcagc gtcatcatac tctattccct
    60061 cttctttatc tctagtatca tctctgacat attgaatccc atcagcagca tgaacaaaac
    60121 ttgtattcag attcctccta aaaataaagt tagcccgatt accgcagaac caaaaatctt
    60181 tccgagttta cgtaatgcat agcgcttatt agtattagat tttgccatta catcctactt
    60241 ctagtatagc atcttttcta tcaaacgtta aacaatatac tttatatata aaatagactt
    60301 agaatgatat attgattatt gaactaacac tttaactata tcgtaatcaa tctcatatat
    60361 aaaggattgc agacatctta tctaaataca tgctaatata tttagataca aacattccaa
    60421 cttgataatt ttcactcatc tttcatcatt ccttatacaa ctatgcagta taaatagaat
    60481 agttttctca tcagaatgag actattttaa tattagataa tttgatagaa aaaacatgaa
    60541 taaaattggt tgaatttaat tccctaactc gatagaggat tctattttaa atttaacaac
    60601 agctaggatt acactataaa aagtacatta ccacctgttc ggctggagaa tctagtcgat
    60661 tagctccctc ttagttacaa gcttaaagcg attttttaac taatactaaa ccagattaaa
    60721 gaaggaacta gaacatctgt cttgtactaa tcaatatgct attttaaagt ttcaaataaa
    60781 cttggaatgc taattattat atttacaata aatagttgac ttcgatagaa acagaaaata
    60841 gaattcaaca ttcttcccta cttataccat aataaataag atccgcaaga tagccttttc
    60901 tctctacacc attaacaatg gtttgtagat aggacattcc agccttttcc atgacacgac
    60961 ctgaagctgg gttgagactg gcataacgtg ctctgacctt ttgaaaacct gcttgagtaa
    61021 aacaaaagtc caagatagct ttcaaagtct ctgtcatcat accatttccc cagtaagcct
    61081 tgcctaacac atagccaatt tcacagctta aatcagcctc gtctatctta acgatgctga
    61141 tatctcctat cacttgctct gggttttctt ttagacaaat ggcccattta taatagttga
    61201 gattagtata ggaagcaacc caattgcgaa tcgagtttcg agtgatttcg atatcaggat
    61261 ggggatccca ggtaacatag gtcagattct cagcagatga agcccaattt tgaaacatgg
    61321 cttctgcatc actctccaca aatcttctta aaatcaaacg ttctgtctgt aatatttgcg
    61381 taccgataga tttcatgatg ctacctcact tccttatttc tatgctcgta gtaaaaaggc
    61441 tcaactcagt aacagctaga aaacgagttt gtcttctaat ttcttgacgc agtcgctgcc
    61501 tggtttgaaa tgcgctctag caagcttttt caaacctagt catcgttgca ggggtaagac
    61561 gatgaaatcg aactcttcga gttaccgaat ctgcctcatt ttcttatttc taaactcggg
    61621 gttcaagatc ccccagacct tctctcactt tcttatttca agatgagagg ctgaaaacct
    61681 ccagtggagg tttttcttgc tttttaattt cagggcaaga agctaaaaag gtccccggac
    61741 cttcttcgct ttctcatttc taggctcagg gtaaaaacct ccaatggagg tttttactcc
    61801 caaaagtcat caaatacagt gatgggtaag tggcgtttgt gttggccttt gtgccaccag
    61861 ttttcaatgg tcgcttgagc ttctgggctg attgttttgc cttctaggta gtcgtcaatc
    61921 tctgcgtagg tgactccaag tgcgacttcg tcagctaggc ctggtttatc ttcttctagg
    61981 tctgccgttg ggattttttc ataaagggct ggctctgcgc caagtttctg caagagctgt
    62041 tttccttggc gtttattgag gcggtaaaga gggagaatat ccgcaccgcc gtcaccaaac
    62101 ttggtaaaga aacctgtgat attttccgcg gcgtggtctg ttccaatgac cgctccgcta
    62161 tgggaaccag caagggcata ctgagcaatc atacggcaac gtgccttgat attccccttg
    62221 ttgaagtctg aaacaggact acctgtcgct tcaactgcag ctgtcatggc atcagctgat
    62281 tccttgatat tcacaaccaa gctgacatct ggctggatga aggctagggc tttttgagca
    62341 tctgcttcat cagcttgcac tccgtatggc aggcggacag cgataaattt gtagctgtcg
    62401 tctcccgttt cagctcgcag ttcttccata gctaattgcg ccaaacgccc tgccaaggtt
    62461 gagtcttgtc ccccagaaat ccctagtaca aaggttttta ggaagggatg ttttttcaga
    62521 tatcttttta agaaatcaat agaacgacgg atttcttcct gggcatcaat cactggtttg
    62581 acacccagct cttggataat cgtttcttgc aaactcattc ttcttctcct tcaccaaggg
    62641 cttccttgcg catcttatca atcaagtcca tcttatcttg ccatacatca cgcgccaaat
    62701 ccactggata gtgctgcgga ttgagcacac gcttatactc atcccacaac ttgtcaaatt
    62761 ccttacgggc ataatcctga atgtcagtca aactaggcaa gttgtaaact aatattcctt
    62821 ctttgaagat atccaccaag agaggaacgg catcaaaatt acgaaccgtc ttcttgatgt
    62881 atgtataggt cggatggaac atcttgattt ctgtcatgtc gctaatatcc acaccatcat
    62941 aagtgatata gtcgccttct gacttgcctt tttcacgact ggtaatgcgc cacacctgct
    63001 tcttacctgg cgtagagact ttttccgcat tattagacag cttaatcgta ttgcgcatct
    63061 gaccagtttc atcttcgatt gcaacaatct tgtaaactgc accaagagct ggctggtcat
    63121 aagctgtaat cagcttggta cccacgcccc agacatcaat cttggccttt tgcatcttga
    63181 gattgaggat ggtattttca tctagatcat tagaagcata aatcttagcc tctgtaaatc
    63241 cagcctcatc cagttgctga cggactttct tagaaatgta ggcaatatcc ccagagtcaa
    63301 tccgcacacc cataaagtta atctgatcac ccagctcacg cgccacctga atggcagctg
    63361 gtacaccgat gcgaagggtg tcataggtat ccacaagaaa gacacaattt ttgtgggtcg
    63421 cagcgtaagc cttgaaagct tcatagtcat tgccataaac ctgtaccaag gcatgggcat
    63481 gggttcccaa aacaggaatg tcaaagagct tacccgcacg cacgttgctg gttccattgg
    63541 cgccaccaat cacagctgcg cgtgttcccc agatggccgc atccatttct tgagcccgac
    63601 gtgtcccaaa ctccatcaag ggttcatctt cgataaccga acgaatacga gctgccttcg
    63661 tcgccaccaa ggtctggtag ttgacgatgt tcaaaagagc cgtttcgacc aactgacatt
    63721 gggctagagg tccttccacc tgcacaatcg gttcattagc aaaaaccaaa tccccttctt
    63781 gggcagaacg aacggtcaac tccaacttga aattgcgaag gtaatccaag aacgccccat
    63841 gataaccaag cgactccaaa taggctatat cactatctga aaaacgcaag tcttcaagat
    63901 agttcacaat tctttccaaa cctgcaaaaa ccgcatagcc gttcttaaaa ggctgttggc
    63961 ggaaatacac ctcaaagacc gccttcttat tgtgaatccc ttggtcaaag taaacctgca
    64021 tcatgttgat ctggtacaag tccgtgtgca atgtcaaact atcatctgga tacatacttt
    64081 tcctacttcc ttagctagaa acccatgaaa attttcaaga actttcatgt attccaataa
    64141 attagtacta ttatatcaca ttttagctgg attgagaaaa gagtaacaag ctattctcca
    64201 ctctccaatt catccatatc ttgttcaaat tttttctgag cccattcgcc atagctctta
    64261 agaccaagat tgccaataaa gacccacgga aggtaaatga cataagtaat gacccaagca
    64321 gacaggtatt taaaattcaa aggattgtgc tgataaattt ctatgttgaa ttgataattc
    64381 tgcaacatca aaagagccgt aatagccaag gttaggaaaa aacaacccaa aatcgtaaaa
    64441 tgaaaacgac tatagtaggt cactcccaga taacgggcac ggttaaaaaa gtaaaatgtc
    64501 cctatgatga taacgattag cagcatatta gaattaaaaa ggcttggtgc taatactgaa
    64561 atgatataag ataggagcga caaagcgatg cagatataga aactttcaga gcccgcttta
    64621 ttgatcagtt gttcttctct ttcgtctagt aattgataat aataaaatct atttttcatc
    64681 ttcttcctcc caaaatagtt ggtctagggt tttccctaaa catctgcaaa tagactggca
    64741 gagcgagaga ctgggattgt attttcccgc ctctatcaaa ccaatagtct ggcgtgtcac
    64801 cccgacagcc tctgccagtt gaccttgtgt taaatcacgc tctacccgag ctaattttaa
    64861 ttttaaattt ttagccacct tcgtcctcct tatagtttta atactcatct actctttaaa
    64921 aatccaaact aacacaagct gtcagctatt tattataacc ccattaattt gcactccagt
    64981 attatcttca gccgaaaatc agtattttag gttgtttgaa ataaacttcc tagtttactc
    65041 ttttattttt atttttattt agcattagct ttagtagaat cttttaaacg agtttttatt
    65101 gcttatattt cttgtttagt ttagttggtt tcatatcact attatataat gcttttggaa
    65161 atgagcctag tataagtcaa aaacgtgttg aatagtgaaa gcaggagcat accaatatga
    65221 ctgatttttt actgtatttt aggtatgcaa aataatacta aatgaaacta aaatgaatac
    65281 ttcttgcttt tcttgagagt gaaaaagtac aataaaatga ttgtagtgat tgccacaaga
    65341 tactgactaa tagacatcgt atttgaagcc acaaatacag gtaaagaata aaaaggaaga
    65401 agttcaattg ctttgataaa caaatcatta ctagtattca tcatcgtatt taatatatta
    65461 gggataaaga gtagtaaagc tactaaaata ccaagccact tttcaatttg tataaataga
    65521 aaatgtaaga taatagaaaa taaaacagga ctaacaaaat tgtattgact acaatagcta
    65581 ctataaaatc taatcctaaa tcacctggaa tacccaattt acttactatg actagtaaca
    65641 caatgccatt caaagcataa ataatggaag ctgagatggc atatagaaaa ttagacaaga
    65701 cgtaaatcat ccgattcttc tgttgattat aaaacaaact taccgtattg tgggaaaaat
    65761 ctctactaat gactcgatta gcatgtataa cagccattaa cataccgagc atagcataaa
    65821 agtttgaaat atgcttaata ccaagcgatg tcccttaagt ctttagaata aagaatgtaa
    65881 gcaatatcgg cggtataaac gagataagca aactgagata tattacgcct gatgaatata
    65941 aatttcttat attttcctta agaaaattca atttatttaa tttcatgatt ataaccttcc
    66001 tttattttga acgatttagg taaatatctt taagcgtctc ttttttagtt tcaaaatcaa
    66061 ctactttaat agagttttcg ttaaaaaatt taaaaagctc actactttga atattcccag
    66121 acatagtaat tctcaatccc tcttcctgaa caatatcccc aaattcttgt ttggtaatga
    66181 aaatgtctct atctgtagct gatgaaaaag ctatctcaaa caagaaatta tgactatctt
    66241 ttcctacttt ttgaaatgtc aaaagcccgt tctccaagaa aagaactctc tcacaaattt
    66301 cttcaatgtc ttctaattta tgactcgata ttaaaattcc cacgttttca tttaaagcta
    66361 atttttttag aaccgctaaa actatttgtg atgattcaat atctaaacca ttagtcggtt
    66421 catctaaaat caatatatca ggttccgtaa cgagagttag aagcaaagct aatttttgtt
    66481 ttgtacccaa agaataggtc tttacttttt tattaataga ctgagtcaaa tctaactctt
    66541 ggatcaaact tctaaatctt tcttgattgt agtcaacacc atataaattt gacaaatatt
    66601 ttaaattctc taaacctgtt ttagataaaa ataattttgg ttcttcgatt aaatacccaa
    66661 cattatcact gcttataata ttacctgaag tcggttgatt attttgaaca agaattttca
    66721 tcaacgtact cttaccaact ccatttctcc ctactagacc aacaatttca cccttgttaa
    66781 gtgcaaaatt tatatctttg agaatgattg aatgaccata atgcttactt acatttttat
    66841 tcctacatta atattcatgg tttactcttt gattcttatt gagtttaaaa agttgcgcct
    66901 ctttttaaca atattatatc atatatctaa cttgatgcaa tatataaatg tcattttgta
    66961 aaattttatt aacaaaaaac tctctacaac aaaataatag agagttttct gcttattaat
    67021 ttttttcaaa atatctaaga catcgcttct ttgtttaatt tgataggctt tgatacctaa
    67081 gctccgactt tatcacttaa aaaataaaaa agacagctaa tctcttgcgc atcaagggat
    67141 ttcgccattc tttaatctcg tttaagtgtt gtatatggag ctttgcataa ttttttaaaa
    67201 ctaaacaact acattaagca cgaactgtga cgctggttcc atcttcctta taaagattga
    67261 taagcccctc tttaagagct cgaaccatgt ctcctgattg aacgggttgt gggac
//
LOCUS       DAVBEM010000005        64216 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVBEM010000005 DAVBEM010000000
VERSION     DAVBEM010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 64216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64216
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.005"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(192..539)
                     /locus_tag="VQ548_000333"
     CDS             complement(192..539)
                     /locus_tag="VQ548_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2653255.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(650..2425)
                     /gene="spxB"
                     /locus_tag="VQ548_000334"
     CDS             complement(650..2425)
                     /gene="spxB"
                     /locus_tag="VQ548_000334"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HET2653256.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(2632..4875)
                     /locus_tag="VQ548_000335"
     CDS             complement(2632..4875)
                     /locus_tag="VQ548_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET2653257.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQSLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(4885..5256)
                     /locus_tag="VQ548_000336"
     CDS             complement(4885..5256)
                     /locus_tag="VQ548_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HET2653258.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QVGEFGFACGMNMMHGKMIVE"
     gene            complement(5267..5662)
                     /locus_tag="VQ548_000337"
     CDS             complement(5267..5662)
                     /locus_tag="VQ548_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HET2653259.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      5846..5944
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6028..6819
                     /gene="thiD"
                     /locus_tag="VQ548_000338"
     CDS             6028..6819
                     /gene="thiD"
                     /locus_tag="VQ548_000338"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET2653260.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEGMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(7028..7660)
                     /locus_tag="VQ548_000339"
     CDS             complement(7028..7660)
                     /locus_tag="VQ548_000339"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET2653261.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(7653..8456)
                     /locus_tag="VQ548_000340"
     CDS             complement(7653..8456)
                     /locus_tag="VQ548_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET2653262.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(8456..8980)
                     /gene="thiW"
                     /locus_tag="VQ548_000341"
     CDS             complement(8456..8980)
                     /gene="thiW"
                     /locus_tag="VQ548_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HET2653263.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERID"
     gene            complement(8985..9677)
                     /gene="tenA"
                     /locus_tag="VQ548_000342"
     CDS             complement(8985..9677)
                     /gene="tenA"
                     /locus_tag="VQ548_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HET2653264.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(9688..10338)
                     /locus_tag="VQ548_000343"
     CDS             complement(9688..10338)
                     /locus_tag="VQ548_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HET2653265.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAIFPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQKLHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAYGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(10340..11725)
                     /locus_tag="VQ548_000344"
     CDS             complement(10340..11725)
                     /locus_tag="VQ548_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2653266.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIVERVQTVGILLQNPNHQFTMESLFEELVFTMENI
                     GYHLQEIDSKIAEVVQQCRCKDILHRLIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELVYDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGSITWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(11726..12286)
                     /locus_tag="VQ548_000345"
     CDS             complement(11726..12286)
                     /locus_tag="VQ548_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2653267.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGFVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(12548..12636)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(12845..13474)
                     /locus_tag="VQ548_000346"
     CDS             complement(12845..13474)
                     /locus_tag="VQ548_000346"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET2653268.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFGTQSKDDAGGTIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(13476..14258)
                     /gene="thiM"
                     /locus_tag="VQ548_000347"
     CDS             complement(13476..14258)
                     /gene="thiM"
                     /locus_tag="VQ548_000347"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET2653269.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVMIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            complement(14501..15169)
                     /locus_tag="VQ548_000348"
     CDS             complement(14501..15169)
                     /locus_tag="VQ548_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HET2653270.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVDKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(15384..15472)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15726..16862)
                     /gene="lctO"
                     /locus_tag="VQ548_000349"
     CDS             complement(15726..16862)
                     /gene="lctO"
                     /locus_tag="VQ548_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HET2653271.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(17487..18977)
                     /gene="lysS"
                     /locus_tag="VQ548_000350"
     CDS             complement(17487..18977)
                     /gene="lysS"
                     /locus_tag="VQ548_000350"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HET2653272.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLITKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKTIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(19105..19251)
                     /locus_tag="VQ548_000351"
     CDS             complement(19105..19251)
                     /locus_tag="VQ548_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HET2653273.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAGDTF
                     TSFQ"
     gene            19477..20145
                     /locus_tag="VQ548_000352"
     CDS             19477..20145
                     /locus_tag="VQ548_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2653274.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRILV
                     LAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFYYVVLPQATAVALPSFSANVIFLIKETSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFGNPST
                     LSRK"
     gene            20105..20782
                     /locus_tag="VQ548_000353"
     CDS             20105..20782
                     /locus_tag="VQ548_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2653275.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIEISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLDFTRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GAAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            20783..21540
                     /locus_tag="VQ548_000354"
                     /pseudo
     CDS             20783..21540
                     /locus_tag="VQ548_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            21552..22413
                     /locus_tag="VQ548_000355"
                     /pseudo
     CDS             21552..22413
                     /locus_tag="VQ548_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(22493..23140)
                     /locus_tag="VQ548_000356"
     CDS             complement(22493..23140)
                     /locus_tag="VQ548_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2653276.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(23137..23835)
                     /locus_tag="VQ548_000357"
     CDS             complement(23137..23835)
                     /locus_tag="VQ548_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653277.1"
                     /translation="MGKLSSHMWRLNKIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDVGGDLFLQLLFLVFLFQ
                     SIFYFTRQKRRFIE"
     gene            complement(23845..24597)
                     /locus_tag="VQ548_000358"
     CDS             complement(23845..24597)
                     /locus_tag="VQ548_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653278.1"
                     /translation="MKQFVQFYKKDFLSVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(24597..25361)
                     /locus_tag="VQ548_000359"
     CDS             complement(24597..25361)
                     /locus_tag="VQ548_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653279.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(25457..25860)
                     /locus_tag="VQ548_000360"
                     /pseudo
     CDS             complement(25457..25860)
                     /locus_tag="VQ548_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(26040..26672)
                     /locus_tag="VQ548_000361"
     CDS             complement(26040..26672)
                     /locus_tag="VQ548_000361"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HET2653280.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYRELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(26706..27407)
                     /gene="pyrF"
                     /locus_tag="VQ548_000362"
     CDS             complement(26706..27407)
                     /gene="pyrF"
                     /locus_tag="VQ548_000362"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HET2653281.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQNWN"
     gene            27728..27820
                     /locus_tag="VQ548_000363"
                     /pseudo
     CDS             27728..27820
                     /locus_tag="VQ548_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011516271.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(28142..28855)
                     /locus_tag="VQ548_000364"
     CDS             complement(28142..28855)
                     /locus_tag="VQ548_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2653282.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQG
                     KVNDQQALVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNKTLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(28848..29543)
                     /locus_tag="VQ548_000365"
     CDS             complement(28848..29543)
                     /locus_tag="VQ548_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2653283.1"
                     /translation="MTGQFLADKGQSIILGQKSQNLTSGELKRIGLVSDTSGFYEKMS
                     LYNNLLFYSKFYNISKSRVDNLLKRVGLYDSRKMVAGKLSTGMRQRMLLARALINKPA
                     VLFLDEPTSGLDPTTSRTIHELILELKTAGTTIFLTTHDMNEATLLCDYVALLNKGKL
                     VEQGAPSELIQRYNKDKKIKVTDYNGNQITFDFTSLEQVSQADLENIFSIHSCEPTLE
                     DIFITLTGGKLNA"
     gene            complement(29883..31215)
                     /locus_tag="VQ548_000366"
                     /pseudo
     CDS             complement(29883..31215)
                     /locus_tag="VQ548_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812020.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
     gene            complement(31199..31997)
                     /locus_tag="VQ548_000367"
                     /pseudo
     CDS             complement(31199..31997)
                     /locus_tag="VQ548_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824573.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M50 family protein"
     gene            complement(32787..33986)
                     /gene="divIB"
                     /locus_tag="VQ548_000368"
     CDS             complement(32787..33986)
                     /gene="divIB"
                     /locus_tag="VQ548_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HET2653284.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(33996..35054)
                     /locus_tag="VQ548_000369"
     CDS             complement(33996..35054)
                     /locus_tag="VQ548_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HET2653285.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVCWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VAKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(35056..36408)
                     /locus_tag="VQ548_000370"
     CDS             complement(35056..36408)
                     /locus_tag="VQ548_000370"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HET2653286.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(36512..37153)
                     /locus_tag="VQ548_000371"
     CDS             complement(36512..37153)
                     /locus_tag="VQ548_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2653287.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTFL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTTSLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(37155..39176)
                     /locus_tag="VQ548_000372"
     CDS             complement(37155..39176)
                     /locus_tag="VQ548_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2653288.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLMSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(39247..39546)
                     /locus_tag="VQ548_000373"
     CDS             complement(39247..39546)
                     /locus_tag="VQ548_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET2653289.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSLVSRWNSHSDKGEASAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            complement(39912..40166)
                     /locus_tag="VQ548_000374"
     CDS             complement(39912..40166)
                     /locus_tag="VQ548_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HET2653290.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(40186..42027)
                     /gene="typA"
                     /locus_tag="VQ548_000375"
     CDS             complement(40186..42027)
                     /gene="typA"
                     /locus_tag="VQ548_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HET2653291.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            42189..42914
                     /locus_tag="VQ548_000376"
     CDS             42189..42914
                     /locus_tag="VQ548_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HET2653292.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVQVNELLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     ESNYRPLNQKELQIIKNYLEMSR"
     gene            complement(42954..43181)
                     /locus_tag="VQ548_000377"
     CDS             complement(42954..43181)
                     /locus_tag="VQ548_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653293.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(43270..43650)
                     /locus_tag="VQ548_000378"
     CDS             complement(43270..43650)
                     /locus_tag="VQ548_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2653294.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(43650..43919)
                     /locus_tag="VQ548_000379"
     CDS             complement(43650..43919)
                     /locus_tag="VQ548_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HET2653295.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            43983..44891
                     /locus_tag="VQ548_000380"
     CDS             43983..44891
                     /locus_tag="VQ548_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET2653296.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(44945..45700)
                     /locus_tag="VQ548_000381"
     CDS             complement(44945..45700)
                     /locus_tag="VQ548_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET2653297.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(45721..46650)
                     /locus_tag="VQ548_000382"
     CDS             complement(45721..46650)
                     /locus_tag="VQ548_000382"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HET2653298.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(46665..47288)
                     /locus_tag="VQ548_000383"
     CDS             complement(46665..47288)
                     /locus_tag="VQ548_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HET2653299.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(47281..48519)
                     /gene="hflX"
                     /locus_tag="VQ548_000384"
     CDS             complement(47281..48519)
                     /gene="hflX"
                     /locus_tag="VQ548_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HET2653300.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(48512..49396)
                     /gene="miaA"
                     /locus_tag="VQ548_000385"
     CDS             complement(48512..49396)
                     /gene="miaA"
                     /locus_tag="VQ548_000385"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HET2653301.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKCFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            49517..49687
                     /locus_tag="VQ548_000386"
     CDS             49517..49687
                     /locus_tag="VQ548_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HET2653302.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(49735..50574)
                     /locus_tag="VQ548_000387"
     CDS             complement(49735..50574)
                     /locus_tag="VQ548_000387"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HET2653303.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPIITLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(50671..51630)
                     /locus_tag="VQ548_000388"
     CDS             complement(50671..51630)
                     /locus_tag="VQ548_000388"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HET2653304.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENTFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(51757..52755)
                     /locus_tag="VQ548_000389"
     CDS             complement(51757..52755)
                     /locus_tag="VQ548_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2653305.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DLHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQAATTQTDTTSSTASGWVKQDGS
                     WYYFDGNGNLVKNAWQGNYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTA
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDG"
     gene            complement(52805..53422)
                     /locus_tag="VQ548_000390"
     CDS             complement(52805..53422)
                     /locus_tag="VQ548_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2653306.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(53423..55144)
                     /gene="pabB"
                     /locus_tag="VQ548_000391"
     CDS             complement(53423..55144)
                     /gene="pabB"
                     /locus_tag="VQ548_000391"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HET2653307.1"
                     /translation="MHRKTVIDFRTLGERYTFAQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(55213..60900)
                     /locus_tag="VQ548_000392"
     CDS             complement(55213..60900)
                     /locus_tag="VQ548_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2653308.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEETPKEEAPRTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKSEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQEDNPKEDRGAEETPKQEESTPDTKAE
                     ETVEPKEETKTAKGTQEEDYVGEALVPEQLPEYKVTEGTLVEESTTELDYKTETTEDP
                     TKYTDEETVLRNGEKGSQVTKTTYKTIGGVKTDQVLSTSTEVTKEPVNQQVIRGTKPI
                     EGTTVETREEIIPFETKEQEDDTLKRGTRQVTQEGVNDKKQITETYKTIRGEKTSDAP
                     TITETVIEKPQDKIIKNGTKELEKPTLEWAKTDKDVLKKSATASYTLTKPAGVEIKSI
                     KVALKDNTGTVVKEVTVEENNLQATLDNLKYYQGYTLSTTMVYDRGNGEETEILEDKE
                     VQLDLKKVEIKDIKETRLMKVDENGNETDSSLLETVPENLTSYYLKITTNHNKVTRLA
                     ITNIEEVTEEETSLFKVTASAPDLIQRDSNNSLSQTYTYYIEKPKASQNNVYYNFKDL
                     VDAMQKNPNGEFKLGSDLNATNVPTPSKSYVTGKFTGHLTSVDGKHFSIHNTARPLFD
                     RVEGGSIKNINLINVNINMPWANQLASLAQTVKNATVENIKVTGTIVGNNNVAGILDK
                     LDDAGIMTNVAFIGKVQSVGDKGWNLAGIASEIYRGNLNKAYADVELKGLNTRAGAIV
                     GHLAHDFNPRDVGAWSNVRNSVAKGTIDVARGDVGGLIGKDWPWGTIDNNISLVNVKR
                     GDIFFGSNDMDDEFVSNWIKPNNATVIGVSSGDKTHKQSSKIKEISQVEADKKIKDMG
                     ITADTFEVTEHLVDKLNRRILRDEEYKTIQDYNANRELVYRNVEKLQPFYNKEWIVNQ
                     GNKLTTDSPLMNKEVLSVTAMKGNDFITDLTDADHIMVHYADKTKDIFTISPKDSQVK
                     QVKEYSVAELGEVVYTPNMVVKDRADLISAIEGILSPIELQSDPIYQRLGRTGDNRVN
                     AIKNLYLEESFKEVKDHLNTFVTKLVENEDHQLNTDEAAKRALIKKIEDNKAAVLLGL
                     TYLNRYYGVKFDNFNIKELMLFKPDFYGKNVSVLDRLIEIGSKEDYIKGSRTQESFRE
                     VVAKNTLSGNLHDFLTYNMKLFTNETDINVWFKKAIENNAYVVEQPSTNPAFANKKYR
                     LYEGLNNGQHGRMILSLLNLKDAHLFMISTYNTISFSSFEKYGKDTEEKRESFKSEIN
                     KRAKEQVNYLDFWSRLATDNVRDKLLKSQNVVPTPVWDNHGAPGGWPDRFGHRKDKPD
                     YAPIREFFGRIDKYHDYKYGYGAYAYIFADPQPMDAVYFVMSDLISEYGTSAFTHETT
                     HVNDRMAYLGGHRHRQGTDLEAFAQGMLQTPAEHGHQGEYGALGLNMAFERSNDGNQW
                     YNPDPTKLQTRDQIDHYMKNYNEAMMMLDYAEAEAVLPKVKGDNSKWFKKIDRETRRP
                     MDRNKLSGPHQWDKVRDLIDAEKTTNLETIDDLVNNNFMTIHGNPGNKVFHPEDFGTA
                     YVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGYYGYEHGFIDYVSSKHQGAANKEN
                     NGLLGDDFIIKKVSNNQFSNLEDWKKQWYGEVLTKSKKGFAPIEINGTQISTYEQLKT
                     MFDEAVTKDLTELNDSSIKDKYRNTVVLKSKVFKALLKNTDGFSGDLFTAPQA"
     gene            complement(60922..61485)
                     /locus_tag="VQ548_000393"
     CDS             complement(60922..61485)
                     /locus_tag="VQ548_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HET2653309.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            complement(61601..63292)
                     /locus_tag="VQ548_000394"
     CDS             complement(61601..63292)
                     /locus_tag="VQ548_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2653310.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(63289..64026)
                     /locus_tag="VQ548_000395"
     CDS             complement(63289..64026)
                     /locus_tag="VQ548_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2653311.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
BASE COUNT        19332 a        13925 c        11337 g        19622 t
ORIGIN      
        1 caaggactgg agaaggaggt gataaagtcc atcgttaatc ggagatggaa tagaatgctt
       61 tttgaaagca gatgagtatt atatgcaatt tctttatata aaaagaccgg attgctccga
      121 tctttcaata gttcatattc tcaatttcta ttttaaaaat agctaaggtt aacgtcaaat
      181 gactacgcga cctatttcat acgataaaaa tcaagcacta gaccagcagg tccttgaact
      241 aataaggact ctgttcccca atcggttaca gttggtccgt gtaaaacctt tataccaagc
      301 tcattcaacc gtttgtagtt ctggtctaca tcctcaacct cgatatgaat aatgattcct
      361 gactgaaagt tttccaaagg aaccaaatga ttttgtgaca acataaggca gtgactacca
      421 atcgtaaact gagcaaaacc atcatcagca taatctgcct ttttatccaa aatatgctcc
      481 aagtcagcac agacttgggg aacatttgaa acgataatat ctaattgatt taaattcatt
      541 tactctcctc cataaaaaga ccgaattgct ccgatctttt aaagttctgc tctatgaaaa
      601 tcaaagaata aagtctacaa gtttcatatt tgattttcgg cgagaggaat tatttaattg
      661 cgcgtgattg caatccttct tcttccaaga agagacggaa tggtacgagt tcttctgctt
      721 cgtatttttc cttgaaggct ttgatagctt cttctgagtg aagttttgga tccaattcaa
      781 gtacttctac tggaagtgga cggtgttgag tgatgcgagc atcgatgaca acagttttac
      841 cttctttgtt caatttaaca gcttctgcaa caactgcatc gatgtcttcg atacggtcaa
      901 ctgtgaatcc aacagctcct tgagcttccg caattttagc gtagtcagcg tttgtgaagt
      961 ctacaccaaa caagtgtttg tttgtatctt cgtatttgtt cttgatgaag ccgtactcag
     1021 catttgagaa gacaaggttg ataactggaa ggtcgtattg aacgtttgtg ataacgtctg
     1081 ggtagcacat gttgaatgct ccatcaccca tgatgttcca tacttggcga tctggattgt
     1141 ctttcttagc agcgatacca ccaggaaggg caatacccat tgtcgcaaag agcggagatg
     1201 tacgccacat attcttaggt gtcatgtgaa ggtgacgagt agatgtttga gtagtgttac
     1261 ctacgtcgat tgagtagata gcgtcttgat cagcatgttt gttgattgca ttgtaaactt
     1321 gatacaattg caattcaccc tcagttttac cttcgagttt gttcatgtaa tcacgccagt
     1381 tttggttgtt cttaacgttt gcacgccacc atggagttga ttcaactggg tttactttgt
     1441 caaggatagc tttagctgct tgaccagcat caccaaggat tgaagcgtca agggcatgac
     1501 gtttaccaag tttgtaaggg tcgatatcga cttggatgaa tttttcagtg ttcttgaatg
     1561 cttcgtaaac ttcagcaaat gggaagtttg aaccaaggaa aagaactgtg tctgcttcaa
     1621 agaccacttc gttggctggt ttccaaccaa cacggtaagc agaacctgtc aaaccttcat
     1681 agttccattc gaaagcttca aagtttttac cagttgtgat gattggtgct ttgattttac
     1741 gtgacaattc agtaatcact tcaccagctt taacaccacc aaatccagca tagataactg
     1801 ggcgttcagc attgttcaag atttcaacag ctttgtcgat ttcaacttcg ttcaaagcag
     1861 gagcgatgaa tgagcgttcg tatgaacctg aaccgtagta tgagttttcg tcgatttctt
     1921 ggaaaccgaa gtttactgga atttcaacaa cagctggacc ttttttagaa attgcagcac
     1981 ggcaggcttc gtcaattact tttggcaatt gctcagcgta agctacacgt ttgttgtaaa
     2041 cagcgatacc gttgtacatt gggttttggt taagctcttg gaaagcatcc atgttcaatt
     2101 cgttaactgg acgtgatcca aggatcgcta ggaatggagt gttatccata gctgcatcgt
     2161 aaacaccgtt aatcaagtga gtcgcacctg gaccacctga accaactgca accccgattg
     2221 agccgccgaa tttagcttgc ataaccgctg caagagcacc tgtctcttcg tggcgaactt
     2281 gtaagaagcg gatatctttg tcttcagcca aagcgtccat caatgagctg agtgttcctg
     2341 atgggatacc gtagattgta tctacgcccc atgttttcaa tacgttaagc attgctgcag
     2401 atgcagtaat tttcccttga gtcataatga taactctcct tcaatttttt tagatttgga
     2461 gaatacgatt acatagaatt ggaaacgttc tccaaatttt tactattcca ctgtatcata
     2521 tttatgctga cttttctaaa aatctgctca aaactctcta ttctctattc taatacagtt
     2581 ttgaaagttc tgtcatttct gttttataac aaagaaatct agtcattact tttagtctat
     2641 tttactaaaa tttaacagaa gggaactggt cagaacagat acagaactaa aggccatggc
     2701 tagacctgcc aattctgggt tgagagccag tccaacacct gaaaagactc ctgctgcaat
     2761 cggaattccg acaacattgt agataaaagc ccagaaaaga ttgagtagaa ttcgatgaaa
     2821 ggttttctta ctcatatcaa aggcacgaac cactcctaaa agattattgg ttgtcaacac
     2881 caaatctgct gactcgatgg cgatatctgt tccagctccc atagcaatcc ccacatctgc
     2941 tacactaagg gcaggagcgt cattgatacc gtccccaaca aaggctactt tccctgactg
     3001 ttgcagttta tggatttcat gggctttttc ttctggcaag acgcctgcaa tgacctcttc
     3061 aattccgatt tgatctgcaa tagcacgcgc cacaccagca ttgtctcctg tcagcatgac
     3121 tgttcggaga ccacgttttt ttagctgact gatggctagc ttagcatttt ccttaggaat
     3181 atcttgcaaa gcaagcaagc ctttgatttc attgtcaaca gctaagaaca caactgtctt
     3241 agcttctttt tctagttctt ctagtttatc ttgataagta ttagaaatat ccataccatc
     3301 cagcatttta gcatttccaa gtaaaacttg ttttccattg attcgccctg aaacaccttt
     3361 cccgtgcaag gactgaaaat tttcaacagt ttgaaactca agtccagctt cactcgctcg
     3421 cttaacgata gcctcagcca gtgggtgttg agaagcatct tccaaggagg ctgccaatcc
     3481 aaacacttct acttcgtcgc cgatgatatc tgttaccaca ggtttccctt ccgtcaaagt
     3541 cccggtctta tcaaagacaa gagtttgaac tttctggatt tcctgtaaga cagttccatt
     3601 tttgaggaga acccccatct tggcactacg tcctgtcccc accataaggg ctgtcggtgt
     3661 tgcaagtccc aaggcacaag gacaggcgat aatcaaaacc gccactccgt agagaagaga
     3721 ggacacaaag ctagctccaa gcacgaccac actatccctg agcaagacga accaaaccca
     3781 aaaggtcatg attcctaaaa tgacaactac tgggacaaaa atccctgaaa tcttatccgt
     3841 caagtcctga atcggcgcac gacttgtctg agctttcttc acaaaatcca caatctgagc
     3901 caaaacagtc tctgagccaa ctttttctgc tctaaagaca agcgttccac tatgattgat
     3961 ggttgagcca atgacagtat ctccaactgt cttgtccaca ggcagactct cacctgtcac
     4021 catggattcg tcaatactag agacaccttc tactacgaca ccatcaacag caatcttttc
     4081 accgggacgc actcgaatca ggtcgcctac cttgacttgt tccaaaggaa cttggacata
     4141 actatcatca ctcaagactt ctgcggtttt agcttgcaag tccagtaatt tctccacagc
     4201 ttgggacgta ttttttctca ttttttcctc aaaaactgct cccaaaagaa cgaaaaagag
     4261 gataaatcca gcactttcga agtaaacagg gagaccagca aagagagcaa ctaggctata
     4321 gaaataagcc actagagttc ccagcgcaac caaggtatcc atgttggcat tgtgcttttt
     4381 aaaactggcc caagcactct ggatatatgg cttacctgca actaacataa taggcgttgt
     4441 tgctagaaag gttccccaat gcatgacttg atgactaatg ctacctgtca acatcccaat
     4501 catgagaatc acaagaggca cagtaaagat actagtaatc caaaaacgtt gcaggagaga
     4561 tagagatttt cgagtcttct caacgactat atagcttccc ttttgcatct tcatgccaca
     4621 agaaaattca tgtcgcccta attcttgagg tgtaaaacga atgactttct cctcatctac
     4681 gccgattggt tccaagatac cttcttcttc aaacagaatt tccttataac agtttgaagg
     4741 agtagcacga tgaaaggtaa tctcagctgg aattcccttt tgaagctgga tatgggctgg
     4801 atgatagcct ttttcagctc ggatacggat tttttgaatg ccattttcta agcttgcttt
     4861 cacaatttct gtcatagtct ccacctactc tacaatcatc ttgccgtgca tcatgttcat
     4921 accacaagca aagccaaact ctccaacctg ctcaggcgtg atttccacta catactcttc
     4981 ccccattggc aggttcgcat gtacaccaaa atctggaaaa acaatttgat ccagacatgg
     5041 tgaaggatcc ttgcggtcaa agacaatgcg tgctggcact gatttcttga ggacaatcaa
     5101 ctcaggagta tagcctccca tgacttccac tcgaatctct tggtatccgt ttttttgctg
     5161 ggctttttgt ccagattttt caggcttttt gaaaaaccaa aacaagataa acgcgataag
     5221 ggcaatacaa ataatggtta caatactatt taacatgacg tctcctttac atacaattac
     5281 atcttacttc tgttacagca cttgatttct tctctgaaat cacagcttcc aagtcttcca
     5341 agtcagtctg agtaaattca cattctacaa tcaagtcagc caacaaattc ctaatcctac
     5401 gggaacaaac cttgtctttg atatcttgga caagtaaatc ccgactttgg tctagagtta
     5461 aaagggctga ataaacaaag gacttgcctt cttttttccg agtcagacac tctttctcaa
     5521 ccaaacgagc caaaagagtt tgaatggtcg acttggacca gtcgaaccgc tctgccaaaa
     5581 ccctaatcaa atctgtactg gtctgctccc cctgcatcca aataatcttc atgacctgcc
     5641 attctgcatc tgaaatctgc attaccatac ctccaaaatc tacatttgtc aattacactc
     5701 atcagtatac tcttaaaatc tacatttgtc aattatagaa ataatatttt cttcgaaaaa
     5761 tagaatttta atcatttgaa aaacgatttg cagtcaaata ttactatata aacaataaaa
     5821 atatgctata ctaaagaaaa aagaaaacaa ccactagggg tgcgtaaagc tgagattaac
     5881 gactgttaga tccctctgac tcaatctagg taatgctagc tgatggaagt ggaaatgata
     5941 atggggacta gcagtcttct attgcctttc taaaacagac tagcttgttc ttaagaatac
     6001 aaacttcagt tggttgggag gttttagatg acttatttac ccgttgcttt gaccattgca
     6061 gggactgacc ctagtggtgg tgctggcatt atggcagatt taaagtcatt ccaagcgaga
     6121 gatgtctatg gaatggctgt tgtaaccagt cttgtcgctc aaaataccag aggtgttcag
     6181 ctaatcgagc acgtttctcc tcaaatgttg aaagcccaat tggagagtgt cttttctgat
     6241 attccacctc aggctgtaaa aactggaatg ttggctacta ctgaaatcat ggaaatcatc
     6301 caaccctatc ttaaaaaact ggattgtccc tatgtccttg atcctgttat ggttgctaca
     6361 agtggagatg ccttgattga ctcaagtgct agagactatc tcaaaacaaa cttactacct
     6421 ctagcaacta ttattacgcc aaatcttcct gaagcagaag agattgttgg tttttcaatc
     6481 catgaccccg aaggcatgca gcgtgctggt cgcctgattt taaaagaatt tggtcctcag
     6541 tctgtggtta tcaaaggcgg acatctcaaa ggtggtgcta aagatttcct ctttaccaag
     6601 aatgaacaat ttgtctggga aagcccacga attcaaacct gtcacaccca tggtactgga
     6661 tgtacctttg ctgcagtgat tactgctgaa ctagccaagg gcaagagtct ttaccaggca
     6721 gttgataagg ccaaggcctt tatcacaaaa gctattcaag atgcccctca actcggtcat
     6781 ggttctggtc cagtcaacca tacaactttt aaagattaag aaaaaaactc tctagttccc
     6841 actttaaggg aattagagag tttttatact cttcgaaaat ctcttcaaat tacgtcagct
     6901 tccatctgca acctcaaaac actgttttga gctgacttcg tcagtcttat ctaaaacctc
     6961 aaggcagtac tttgagcaac ctgcgactag ctttctagtt tactctttga ttttcattga
     7021 gtattaatta ggaaagaatg tcatgcaact ttgttaaaaa ggcttgcgtt tttgcctcaa
     7081 tatcttctgc ttgcatcaaa tcacgtacaa cagctacacc agctatgcca gtgcccataa
     7141 gctgatcaat attctccgaa gtcaagcctc caatagcaac tactggaatg gcaaccgttt
     7201 ggcaaattgt tttcaaggtc gatatcagag taatgggcgc attttccttg gtggtggttg
     7261 ggaaaatggc tcctgtaccc aagtaatctg cacctgattt ctccgcttcc agagctcttt
     7321 taaccgtttt agcggtgaca ccgaggattt tttcaggacc caagactttg cgagctaccg
     7381 aaactggtaa ttcatcatct ccgatatgca gacctgctgc atcaaccgca agacaaacat
     7441 ccaaccgatc atcgattatc aaggggacct gataggcatc tgttatttcc ttgacttgtt
     7501 ttgccagttg ataatattga ttggttgtga gatttttttc tcgcaattgg actatggtaa
     7561 cccctgaacg gcaggccgtc tcaacttttg caagaaagct ttccacggaa tcttgatagc
     7621 gattggttac cagatatagt ctaagtgctt ctctattcat aaacctctcc tttgatggta
     7681 tctagccaat tttcatctct tcttaggagc gaaagctgat tgagtacttg gtaacgaaat
     7741 tcttccaatc ccattccttg aacaactatt ttctcagcag cgatattgag ataagagact
     7801 gctaagcaag aagcttcaaa accagtcttt ccttggctga gaaaaacggc tgttaaggct
     7861 ccaaccaagt ctcctgtccc tgttatccag tctaattcag tacagccatt ctccagtaca
     7921 gcaacttgat tctccgaaac aataaggtcc ttggggccag taactaagaa agacatacca
     7981 ggataggtct gacaccagtc tttcaagact tgaagcaaat cctccgtttc ttgatcttta
     8041 gcactcgcat cgaccccaac gccgtggtgc tttaatccaa caagacttcg aatttctgac
     8101 atgtttcctt taaggaccgt aggtctatag tctaaaaggt ctttaactaa gctcttacga
     8161 atggatgaag tcgttacgcc aaccgcatct actaccatcg ggagagaaga ttggtttgca
     8221 tacgaagctg ccatgcggat tgctttttcc ttctcagctg acaaatgccc caaattgatg
     8281 aagagagcct gactttgctt agtaaaatca agaacttcac ggggatcatc tgccatgaca
     8341 ggtttgcatc ccagagccaa aatcccattt gccagcatct cacaagaaat ctcattggtc
     8401 atacagtgaa tgagggaact agagcctata ggaaaaggat ttgtcaatgc ctgcatcagt
     8461 ctatcctttc agcaaagaaa tatccttgca cttttttaaa gaattcctgc ttgattaaaa
     8521 atctaaatgc aataaaggaa atcgctgtac caatcaaggt tgctccgaaa aatcgaggag
     8581 tgtagataaa ccaactaagc ttagcagccg atcctgtaaa gagcaccata acaggatagg
     8641 aaacaataga accaataata cctgttccca caatttctcc caaggcagaa aagtaaaatt
     8701 ttcgaccgta cttataaaag agacctgcta gaagggctcc aaaagtcgct cctgtgagag
     8761 ctaaaggcgg aatcccttga gtcgtcatac ggataaaggc tgtcactgta gccatagcca
     8821 aggcataaac aggtcccatc atgattcccg ctagaatatt gactacactg gacatcggtg
     8881 ccattccctc aatccgaaag ataggtgtaa ggactacatc aagggcaatc atcatagata
     8941 aaatggtcaa tttgtgaact tgtagttggt gctttctcat gtttctattc ttctcctttt
     9001 tctaaagact gtaaatcgct cttccatgtc tggtgttggt aagccatctc ccaaaacttg
     9061 gcttccatat gaacactgat gtggaaggca tctagcattt tttgcttatc tgtctcatca
     9121 ctttctcgat aaagctgatt gaccagtgct ccctcctctc tgatctgttg ctctaactca
     9181 tccgtaatat aagtttcaat ccattgttga tagagaggat ttggtgatgg tttaagatta
     9241 agtgatttgc ctatatcatg gtataaccaa ggacaaggaa gcaagcttgc aaaagctatg
     9301 gctaagttcg gttctgcaaa ttgcctataa atatgagaaa tgtaatgata acaggttgga
     9361 gcgattggat gttgctccat ttcctggtcg ttgatttcca attccttgaa aaattgttgg
     9421 cgaataaata actcaccctc cactaaaccc tgagcatttt gtttcaagag tcttttcatc
     9481 tcttggtttg aagtcttatc agccaaaaga tgatagattt ctgagaaagc cttcagatag
     9541 taggcatcct gaatcaggta atagcggaaa atggcaggtt ctaaattccc ctcttgtaat
     9601 tgtaaaataa agggatgatg aaaggaagcc tgccaagctt tcttggataa ttccatcgca
     9661 atatctgtaa attccataat aactccttta taaaaataga ctggtttgaa gcaataaaaa
     9721 gaaaagcagg tagattaatt ttgttttttt aggaatataa aaagtccgat agctattctt
     9781 caactgtgca tgttcgtcat atccgtaagc agatagagct ctcaggtaaa gatggcgcca
     9841 cctaaagact gtcatcagaa ccttactgta aatcaagggc gaccaaaaat gtagtttttg
     9901 accacgtaat aggcaagctt ctttgaggga cttgatttct tgctgaatga gaggaaaaga
     9961 attgaatacc acaatcaagg cataggacca agagcgtgat agcccctttt gagccaagta
    10021 caagagaagc tcttttagtg aaatagagga aacaaagaca aggccgatac aaactgtcac
    10081 aaaggccctc gttccaagca tgactgcctg tgaagcatct ccgtgtaact gaactgccca
    10141 gtagttggca aaagatggga aaatggcaag tatgatcatc caagctaaca ttttaaatcg
    10201 acggtaatag agcataaaga gaatacaaaa tgcgactacc gaaagattca gagcaatcga
    10261 aggaatgaaa gatgtttcca aggataaaat cagcaagaag agactgataa tcggtgtctg
    10321 ggttgctact ttgaccatac tatctcacct ccccttgggt attgctactc tgagatgtaa
    10381 gtggtttggt aatggtcact tctttcacat gccgaagacc ctgactagtc atctcaatcc
    10441 aataatcaac cacagaaatc aaagggtcta aacgatgact aatgagcaga aaacttcttc
    10501 cttgattcct ctcctccaca atccacttgc aaaaataatg gcaggctcta tcatccaaac
    10561 ctgcaaaagg ttcatctagc aagatcacgg aagccttact ggtcaagatg gtcaggagct
    10621 gaagaatttt ttgctgacca ccacttaatt gatagggact cttatcgact gcctgctcca
    10681 aatcaaaata tcgtaaagct tgaaaaatcc gctgatttct ttcagaatca ggtccatcta
    10741 attgaagctc ctctcgcaga ctgactcgga taaactgctt ctcagcttcc tgaacaacac
    10801 cagtcagatc acgatacaaa ctctttttct ttttcaggac cgaacccttc caagtaatgc
    10861 tccccttata cttttgaaat tgaagaatag accgaaagag ggttgatttc ccgacaccat
    10921 tgtcacccag gatacaggaa atcccttgat agaatgtgaa atcagcaatt gaaaagaggg
    10981 ggcgattacc aagctcacca gtcacacggt tcatatggaa tagttccggg ctagaagcaa
    11041 cttcctttga agcaacctgt gtcatctcat aggaagggat ttgaaacact tcccttagtt
    11101 ttccgtctct tagctccacc atatggtcga tataggcttt atagtcagat aaatcatggt
    11161 cgcacaaaat aactgtcttc ccatcataga ccaactcttt tagaatctcc aatatctcga
    11221 ttctgctctt gcggtcaatg gaagcgaagg gctcatccaa gagatagacc ctaggattca
    11281 tggcaaagag gacagccagc gctgcttttt gcttttcccc acctgataag tgatggatga
    11341 gacggtgcaa gatgtccttg caacgacatt gctggacaac ctctgctatt ttagaatcaa
    11401 tttcctgaag gtgatagccg atattttcca tggtaaaaac caactcctca aacaagctct
    11461 ccatggtaaa ttgatgatta ggattttgca agagaatacc aaccgtctgg acacgttcga
    11521 cgatagaaag ctgactgacc tcgctcccat ctatcaggac ttgaccgcta tagggaagag
    11581 aactaacttg ggcaatcatt tgaaagaggc tggattttcc agacccacta ctcccaacta
    11641 acaaggtaaa ggcttgcgca tgaaaagtaa aatcaaacgg ctcagagaag attggggact
    11701 gaatcgctcg tagttccaga cccatctatg cttttcctcc agttgcaaac tgatgataga
    11761 gtttgacaat ggcacgaacc aagatggtac agaagaaata aacagaaata aaacgtacca
    11821 caagcaagga aaggacaaac ggaagggaaa aggcgtagta acctaactta atgtattcat
    11881 agacaaagct aacaagcgta atcccaatac tattagcagt tagagagagc caactttcat
    11941 agcgattctt agttacgata aaaccaaatt cacttcccaa accttgaaca aagccagaca
    12001 aaagagctcc tagaccaaat tggctaccat aaaggacttc agcaagcgca gctagcactt
    12061 ctccaatcgt tgcacttccg actctcggaa caaagatggc agcaatgggc gcagccatac
    12121 accagagacc gaagaggatt tcattggcaa aggcctgcaa accaagaggt gttaagagta
    12181 gactgagaat attatacaca tatcctgaac caacgaaaac cccaccaaaa aagatagaca
    12241 agaaagcaag caagataaca tcttttaact gccatttttt caacataaaa aactcctttt
    12301 tttaaagaaa agtggggcac tcaagaagac cgacctaaat actttgtata gcagactgaa
    12361 tttagaacag tacacaagaa cactaaaata tttctagaaa ttaatttgaa ttttctaatt
    12421 gatttgttcg catcttattt caatctacta tatcatcttc atccagtttc gtaaaagaaa
    12481 aaactctaat tacagataca aattagagtt cagcttacaa gattagacag ttcttttcga
    12541 catacgaaaa aaacatttca catttccctt cgccagtctt aactgtatca ggttcaatgg
    12601 gtatcatctc agcctaaagc accccaaatg tctttattat ttaattatgt gattattata
    12661 acacacattt tatactagtt caagaaattg aactggaaat acagccttgc actcacaaag
    12721 acagcagatc tttcttttgc aaaaaacaaa tgacctgttt gatgaattag ccattcaagc
    12781 tgaatctgga catagctttt taaaaaagga aaatcctact tacttagaat ccaaggatag
    12841 atatctattg ttcactcatt tcccgaacag ttttttctat attttttgca tacgatattg
    12901 ccgaaatgat tgaaacgcca tccatattgg tctttataat gtctttaata tgtttcgtct
    12961 gtatcccacc aattgcaact aaaggcattt gtggcaatag ttttctcatc aattcaagac
    13021 cttcataacc tatagtacca ccagcatcat cctttgactg ggtaccaaat acaggcccaa
    13081 cacctacata atctacatat tcaacttttg attgttgaaa ttcttcttcg tttcttatag
    13141 aaagaccaat tattttatct ggcatcaatt ttctaatttc atcaacacca atatcatctt
    13201 gacctacatg tacgccatcg gcgtcaattt ccattgctaa atctatatcg tcattaacga
    13261 taaatggaac attgtatttt ttacaaagtt ctttaatttg gatagctagc tcaagttttt
    13321 ctaagccttc taaagcaccc tcaccttttt ctcgaaattg aaataaggtt ataccacctt
    13381 ttaaggcttc ctcaacgact gtatatagat tttttccttg gcaagtagtc gttccacaaa
    13441 taaaatatag ttttagtaat tctttatgaa acatcttact tcactctttt gaattccttt
    13501 acatcttcat ctgtaatctc gtataaggca tttataaatt caactttaaa tgtcccagga
    13561 agatgtccat ttggacgttt ttctgccatt tctccagcga tattgtaaac caacattgct
    13621 gtttctaatg atttcaattc ttgacctttt tctagtccga taaagcttgc tactacagct
    13681 cctaataagc atcctgtccc aatgactttc ggcatcatag cactaccatt atgaatcatt
    13741 accacttctc cattaacagc aatggcatcc acttcacctg ttactactat tggaatattg
    13801 aacttctcat ttgctgctag agcaatttcg tcaatattat ctacgcccgc actatctact
    13861 cctttagatg ccacatctat tcctactaaa gaggcaatct cgccagcatt tcctctaatc
    13921 gctgctagtt tataattgtt gattagatca tctgctactt tttttctata ttctcctgct
    13981 ccacaggcta caggatctaa aactgctggg acattatatt tctctgcaat tttcagagca
    14041 gcttggtata atttccaatt ttcatctgtc aatgttccta tgtttattaa taaaccacca
    14101 gcatacttta acaaatcctc taaatctgct ggaaactcac tcatggctgg tgaggcgccc
    14161 agtgctacta atccatttgc tgtgaaattt tttactacat cattggttat acaaatgacc
    14221 aatggtgctt tttcttttaa taattttaaa cttgtcatat tgaaatcctt ccttttcact
    14281 ttatacgatc tactgatttc gatttatttc tatctttcgt taagaatttt tttcatttac
    14341 attgaatgat ttatactcaa tgaaaatcaa agagcaaact aggaggctaa ccgcaggttg
    14401 ctcaaaacac tgttttgagg ttgtggatag aactgacgtg gtttgaagag attttcgaag
    14461 agtcttacct catcaaattt gtaaatatca tgagccttct ctagacatcg taaccaatat
    14521 caaaaaaagc taattctaaa gcgactgctt gattccagcg ttgctgaagt tctgtcaaat
    14581 cttctcgatt tttatcgaca cgattgagtt cgtcaaccag aaattgaacc cactctgcaa
    14641 agaaaggacc tctgtggaga ttgatccatt ccgaatgaat atagacttca ggtaaagcca
    14701 aatctttaga accccagtct aaatagagac cttctgcaat gaccagcatg accaaaagat
    14761 gggcatagtc tgatgaagcc accgccgaat acattagatc ctgaaaggct tttgttacag
    14821 ggtgcaaagt cacttctaga tagtcattct ctgctacttt taactcttta aaagcctttt
    14881 ggaaataacc atcttcatct gcttcaagaa agcctagttg cttggcaaaa cgaagcttgg
    14941 attcaagttt atctgcgtga gctacgcagg cacccagcat ggataagaag gcatcaaaga
    15001 agtgataatc ttgaatcaga tagtccttta agaccttatt ctcaattgtc cccgcaaaaa
    15061 gttccttaac aaaacgatga ttgattgcag cctgccaatc cttctgactg ctttttaata
    15121 attctccaac agtcaaacct ggctgaaatg catagtcttg tgtttccata tttacttctc
    15181 ctctctttac ttgttagtaa ttaataaaac accaagaaat atcaagcaaa atcgtaattc
    15241 cacttgatcc ttttaaagca catcgagagc atttgcagag agctaactaa acaagcctat
    15301 ccagtttata taaacaaaaa actccaatta caatcaagaa ttagagttga cttacaagat
    15361 tagatcgttc atttcgccat acgaaaaaac gtttcacatt tcccttcgcc agtcttaact
    15421 gtatcaggtt caatgggtat tatctcagcc taaagcaccc caaatgtctc tattatttaa
    15481 ttactgaacc agtatagcaa aaaatgaaag ccctagcaag atatttgacc gaaaaatatc
    15541 tttatatata atatattgaa actagaatag tacacctcta cttctaaaac attgttagaa
    15601 atcgatttga ctgtcctgat tgatttgtcc tattcttatt tcattttact atagttttcg
    15661 atagcaattt attcttccaa tacacgaaga aaaacctcca cattcagtgg aggcaatctg
    15721 ttttatcaat acaattttaa gtcacgaggg tcaactggga aggttgggtt gtatggattg
    15781 tgacggagct taaagtgttt gacatcttca atggtctgag ctccagacaa ttgcataact
    15841 gtcttcaatt ccgcattcaa gtgttcaaag acttgacgca caccgacact accaccgaga
    15901 gccaagccat aaataacagg gcgaccaata gctaccaagt ctgctcctga agccaaggct
    15961 ttaaagacgt gttgaccacg acgaacacca gagtcaaaga caatcggcac acgtctatca
    16021 actgcttctg ccacttcttg aagcgagtca aaggcagctg gtccaccgtc gatttgacga
    16081 ccaccgtggt tggttaccca gataccagaa gctcctgcag caagtgaacg ttcaacgtcc
    16141 tcacggcatt gtggtccctt gacatacaca ggaagaccag agtattcagc gataaattct
    16201 acatcgcgtg gagacaagcg ttgtttagct gatttgtaaa caaagtccat tgatttacca
    16261 gcaccttctg gcaggtattc ttcaacaatc ggcatgccaa ctgggaagac aaaaccatta
    16321 cgcttatcca cttcacgatt cccccctaca gtagcatctg ccgtcaagac aatcgcttta
    16381 taaccttcag ccttcacacg gtccatgatg tggcggttga taccgtcatc cttactaaag
    16441 taaaattgga accaatgggg tgtcccttga agggcttcag aaatctctgg aaggtcaaca
    16501 gtagagtaag agctggttgt ataaagagaa ccaaactcat gcacaccacg cgcagtcgcc
    16561 acttccccct gttcatttgc caatttatga gccgcaacag gcgccataat gattggtgaa
    16621 gatagttttt cacctgcaaa ttcaatctct gtacttggat tttcaacatc gcaaagtgta
    16681 tgaggaacga tgagtttgtg gttaaaggcg cggatattct ctcttaaagt gaaagtatct
    16741 tccgccccac tagcgatata gccaaatgct gctttaggaa taacttgttg cgccattggc
    16801 tccaaatcat aggtattgat gaagtctaca tgaccttctg cattgcttgt tttgtatgac
    16861 ataaaatgcc ctccttgatt aagtaagcgt ttgcttttta ctacacaact ataataactc
    16921 ttttttcaat cattttcaag agttttgctt aaaaaccatc ttattttttc atacaatata
    16981 ctagccctac tttccttaaa ctctaaactt tagtctatat taagtgaatc gttgagattt
    17041 tttgctgcca ggcatttgaa ctactttttt atttgcggat tctatctact aatactataa
    17101 aaaaacaagt gaataagaca ccagaacatc ctctaatagg acctatggac ttatatcagt
    17161 cccatatata ctgtttaagc aagatactat cctagttgac gctaacttcc tatcccactt
    17221 attaattttt tatttatagt gaatctgaac aaatcaattg gggaatccaa gtcaatttct
    17281 agtacttttt gaacagtttc agcgtactat cgtaaaatga aataaaacat gcacaaattg
    17341 cttagggaat ttaaaccaat ttctaacaat gtcttagaaa tcaaagtgta ctatttcaac
    17401 ttcaatatac tacacttcat tttctcctta aattcagtct ctttttgaat caaaaaatcc
    17461 cctggtaaga gccagaggat aagaatttat ttcattgttg ggaagagcaa tacatcacgg
    17521 atagttgttg tatcagtgag gagcatgcag agacggtcga taccgattcc caaaccacct
    17581 gttggtggca taccgtattc aagagcttca atgtagtcat agtcgatgcc tgtcgcttca
    17641 tcatcaccaa gttctttggc tttagcttgg gcttcaaaac ggctaagttg gtcgattggg
    17701 tcgttcaact cagtaaaggc attaccgtac tccttagtca tgataaagag ctcgaaacgg
    17761 tcagtaaagc gttggtcttc aggatttttc ttagcgagtg gagatacagc tactggatgt
    17821 ccatagacaa aggttggttg gattaaagtt tcttcaacaa actcttcaaa gaaggcattg
    17881 atgatgtgac caacctcagt gtagtgtttc tcaactggaa ctttcttctc agcagcgata
    17941 gttttagctt cttccaaagt catgtcttgc cagaaatcga caccagtaat ttctctgata
    18001 gcatccacca tatgaacacg cttaaatggt tcgttaatct tgatttcagt accttggtag
    18061 ttgactgggc catcaccttt gactgattta gcagcgtgtt ggataatgcc ttcagtcaag
    18121 tccatgatgt cttggaagtc tgcataagct tggtaaactt cgatagaagt gaactcaggg
    18181 ttatgagtag cgtccattcc ttcgttacgg aagatacggc caatttcata gacacgttcc
    18241 ataccaccca cgataaggcg tttcaagtga agctcagtcg cgatacgaag caccatgtca
    18301 atgttttggg cattgtggtg ggtgataaat ggacgggcag cagcaccacc ggcttcatta
    18361 tgaagaacag gtgtttccac ttcaaggaat cctttttggt caaggtaacg acggatttca
    18421 gagatgattt ttgaacgagt gacaaagcgt tcaaagcttt cacgattaga aatcaagtca
    18481 aggtaacgtt tacggtaaat tgtttcaacg tctgtcaaac catggaattt ctcaggaaga
    18541 ggacgaagag ccttagacaa gtgtgtgatg tgggttgcct tgatagagag ttctcccata
    18601 tccgtacgca tcacttcacc ttcgacacca aggaagtcac caaggtctgc ttttttgaag
    18661 atttcgtagt tttcttcacc gacagcatcc ttacgaacgt agatctgaat ctggccttcg
    18721 cggtcttgaa ggtgggcaaa accaactttt cctttaccac gtttggttat caagcgtcct
    18781 gcgatagtag ctgtttcgtt tttatcgtgt aattgttctt tatcgaggtt ggcatattta
    18841 tcttttaatt cttgtgaatt tgcagtacgt tcaaaacgtt ttccgaaagg atcgattcct
    18901 tgttcgcgga gcgcagccat tttttcacgg cgaacgatct gctggtcatt tagttcttcc
    18961 atatgttctg tagacatggg atcctcctag ttttactcaa aattgaatac gatgagtcat
    19021 tttttgcgat actcccattt tatcataaat aagcaagaaa ttcacggata atctttaaaa
    19081 actaaaaaga acctgacgct aaaatcactg gaaagaagtg aaagtatctc ccgccccact
    19141 agcgatatag ccaaatgctg ctttaggaat aacttgttgc gccattggct ccaaatcata
    19201 ggtattgatg aaatctacat gaccttctgc attgcttgtt ttgtatgaca taaaatgtcc
    19261 tccttaataa gtaagcgttt actttgtgta ttacaaaaat atcttaactc tttttcaaaa
    19321 cttttaaaat attttgtttg gaaatttcag aaattttatg tctatgataa aaatccttat
    19381 aacggcaata aaaaatagat attatccaaa gaagatttta agtgctacaa taactgtatt
    19441 atttctagat gggaggttct atttttggat tgatccattg ttgaacaata tctaccacta
    19501 tatcaaaagg cattctttct gaccttgcat attgcagttt ggggaatttt gggatccttt
    19561 ctgctcggtt taatcgttag tatcatccga cattatcgaa tccttgtttt ggcgcaagta
    19621 gcgacagcct acattgaatt gtcacgtaat acgccccttt tgattcaact cttctttctc
    19681 tacttcggtc ttccccgaat cgggattgtc ctatcttcag aagtctgtgc aacgcttggg
    19741 cttgtctttt taggaggctc ctatatggca gaatctttcc gaagtgggct ggaagccatc
    19801 agtcaaaccc agcaggagat tggcctcgct attggtctga cacctctaca ggtcttttac
    19861 tatgtggttc ttccgcaagc aacagcggtg gcactcccct cctttagtgc caatgtcatt
    19921 ttccttatca aggaaacctc tgttttctca gcagtggctt tggccgacct catgtacgtc
    19981 gccaaggatt tgattggtct ctactatgag acagacattg cgctagctat gttggtagtt
    20041 gcttatctga tcatgctgct acccatctca ctggtcttta gctggataga aaggaggctc
    20101 cgccatgcag gattcgggaa tccaagtact ctttcaagga aataatctcc tgagaatctt
    20161 acagggattg ggcgttacga ttgagatatc catcctgtct gtcctcttat ccatgatgtt
    20221 cggaacagtc atgggaatca tcatgacctc ccattctaga atcatacgat ttttaacacg
    20281 attgtatctg gactttaccc gtatcatgcc ccagctggtg ctactcttca tcgtttactt
    20341 tggcttagct cgaaacttta atatcaatat ctcaggtgag acttcagcta ttatcgtttt
    20401 taccctctgg ggagcagctg aaatgggaga cttggtacgt ggagctatca cttctctccc
    20461 taaacatcag tttgaaagtg gacaggcact cggcttgact aatgttcaac tttactacca
    20521 catcatcatc ccacaagtct taagaagact gctaccgcag gctatcaatc ttgtcactcg
    20581 gatgattaaa accacttcat tagttgtttt gattggggtt gtggaagtga ccaaagttgg
    20641 acaacaaatc atcgatagca atcgcctgac catcccaact gcttcatttt ggatttatgg
    20701 aaccattcta gtcttatatt tcgcagtttg ctaccctatt tccaaactat ccactcactt
    20761 agaaaaacat tggagaaact aaatgtctga aactatctta gaaatcaagg aactaaaaaa
    20821 atccttcgga gacaatccca tcctccaagg actttctcta gaaatcaaaa aagggaagtt
    20881 gttgtcatcc tagggccatc tggttgtggg aaaagtaccc tccttcgttg cctcaacggc
    20941 ttagaaagta ttcaaggtgg agatattctt ctggatggtc agtctatcgt tgaaaataaa
    21001 aaagattttc acctagttcg ccaaaagatt ggcatggtct ttcaaagtta tgaactcttt
    21061 ccccatctgg atgtcttaca aaacctcatc ctaggcccta tcaaagctca aggaagggac
    21121 aagaaagaag taacggaaga agctttgcaa ttactagagc gtgtcggttt gctggataaa
    21181 caacatagct ttgcccgtca attatctggt ggacagaagc aacgtgttgc aattgtccgt
    21241 gccctcctaa tgcatccaga aatcatcctt tttgacgagg tgactgcttc gctggatcca
    21301 gaaatggtgc gtgaggtgct ggaacttatc aatgatttgg cccaagaagg ccgtaccatg
    21361 attttagtaa cccacgaaat gcagtttgcc caagccattg ctgaccggat tatcttcctc
    21421 gaccaaggga aaatcgctga agaaggaaca gctcaagcct tctttaccaa tccgcaaacc
    21481 aaacgagccc aggaattttt aaacgtcttt gactttagcc aattcggctc atatctataa
    21541 aggagattct tatgaaacta ttcaaaccac tcttaactgt tttagcactt gcctttgccc
    21601 ttatctttat cactgcttgt agctcaggtg gaaacgctgg ttcatcctct ggaaaaacaa
    21661 ctgccaaagc tcgcactatc gatgaaatca aaaaaaaagc ggtgaactgc gaatcgccgt
    21721 gtttggagat aaaaaaccgt ttggctacgt tgacaatgat ggttcttacc aaggctacga
    21781 tattgaacta gggaaccaac tagctcaaga ccttggtgtc aaggttaaat acatttcagt
    21841 cgatgctgcc aaccgtgcgg aatacttgat ttcaaacaag gtagatatta ctcttgctaa
    21901 ctttacagta actgacgaac gtaagaaaca agttgatttt gcccttccat atatgaaagt
    21961 ttctctgggt gtcgtatcac ctaagactgg tctcattaca gacgtcaaac aacttgaagg
    22021 taaaacctta attgtcacaa aaggaacgac tgctgagact tattttgaaa agaatcatcc
    22081 agaaatcaaa ctccaaaaat acgaccaata cagtgactct taccaagctc ttcttgacgg
    22141 acgtggagat gccttttcaa ctgacaatac ggaagttcta gcttgggcgc ttgaaaataa
    22201 aggatttgaa gtaggaatta cttccctcgg tgatcccgat accattgcgg cagcagttca
    22261 aaaaggcaac caagaattgc tagacttcat caataaagat attgaaaaat tagcaaggaa
    22321 aacttcttcc acaaggccta tgaaaaaaca cttcacccaa cctacggtga cgctgctaaa
    22381 gcagatgacc tggttgttga aggtggtcat taactcttaa aagggactgg attttaagct
    22441 ccaatccctt tttaagattt tacctataac atcctgagtc tatctaagat gttcaatctg
    22501 aacacagtgt acatacttta tcttctattg catatacttt atcacataag atacgaatat
    22561 cctcttcact atgactagca atcaaaattg ttgtcccttt ttcactagag agctttctaa
    22621 acaatgttct catattttct acacttgatt tatccaaggc attcataggt tcatctagta
    22681 aaagaataga gggattctcc atgattgctt gagcaatccc tagctttttc ctcataccta
    22741 gcgaataagt tttaactttc tggtcttttt gctcatatag accaactatt ttcagtgtat
    22801 cattgatttc ctgattacca actactcctc gtatgcttgc caaatattgt aaattcttaa
    22861 agccactata ataatttata aaaccaggtt cttcaatcaa agctcccaaa ttagctggaa
    22921 tttttctctc aggaacaata ttttccccat tgattaacac ttctccataa gacggactat
    22981 ataaaccagc tattaattta aacaatacac ttttccctga gccattcgca ccagtaattc
    23041 ctataatttc cccctgttta caactaaagt taaggttttg aaaaacacat gtctttttta
    23101 atttcaactc aatatttttt aatataatta tttcattcat tctataaacc tcctcttttg
    23161 acgagtgaaa tagaaaatgc tttgaaaaag aaagactaaa aatagcaact gaagaaacaa
    23221 atctccccct acatccccat tccctcgatt caaaatataa aatagataat tagttcgatt
    23281 tcctacaaat agaccaccaa acacaatcat gagtaaaaag aaactaacgc aagcaaagtt
    23341 catttgtaca ttcgctccta gtgcgtataa cataaagcaa aacaagacta acacacaagc
    23401 attcaaagaa tcaactataa acaaaactcc tatatcccag tttggtaact gtaacataaa
    23461 ttgaatcact agaactttta ccatgattaa aatgagtcca taaagaaaac aggtccaaat
    23521 ctgataccta atccagagct taatagaaga aaatcgaatc acttccataa agaaatcgga
    23581 tgctcttcta cgatatacaa ctgctagaaa aaatgtatga ataataaacc aatgaagcaa
    23641 ccatatagat aagactaaaa aagagttttg actcagatta ggccctttta aaatttctat
    23701 aacaagtcta tcatttcctt ctaaccaata ccataatcct aaacaaatca atatccaaaa
    23761 aagaacataa ccccaaaagt acttggtata gattatctta ttcaacctcc acatgtgact
    23821 acttaacttt cccatttcca acttttacac tctcctccag tttctatgaa cagaaaatac
    23881 agtcaatgga attatgatag atagtaatgt aagccaataa atcaatgcat acggattgga
    23941 atttaccata tactgaaaaa ttggcaataa tccaattatc ccattgttca actgataaat
    24001 ccagaataag gattctacaa ataaaaaagt aaacagaaat actaagctca tgtttgattt
    24061 tttaaaccaa gaaaaactgc taatagtaag taaggataaa aagaaatagt atgctatata
    24121 agagaaaaaa aatcctataa agaaactagc attgtttgca atacttatac cataaaattc
    24181 tcttaaaaaa tcaacctcct ttatctccaa agagaagcta aaaccattac taaatgcaat
    24241 tagaaaaatc aataaaaata aagtcgccgt ccaaatcccc gtactaagag ctgctaattt
    24301 gaaactaaaa ctggtaaagt gcttaattga tttcagacga atgcgacact ccaacctatt
    24361 aaaatagtta ttcatcaaat aaaaaaagaa caatatatat gtgaacggaa agcaatatac
    24421 tccagtcgtc atatcttgaa gtaaaactaa aatccattct aatacatttg gatggattga
    24481 atattggcga cagcgcaata aatatactgt actagataaa acacaggata gcagtaatat
    24541 aaaataaacc aatactgata aaaaatcttt tttgtaaaat tgaacaaatt gtttcattat
    24601 acatagtcct ctgaatgtag aaaaaatgta ccataaacaa ccaaacaact aacaaataaa
    24661 ataaaagcaa gatgcccact aactaaggaa agactgatat ctttctgata tcccaaagct
    24721 aatgttgtca caggttctaa gtaagatagc cctaaaatag cccaaaaaat accaccaacc
    24781 atcatatagg caactgggat gaaaatagct cctatttttt tcttcactag caaagcacta
    24841 gctagtccaa aaatagagaa cacagcgccc caaactccat accagagagt cgtcacaaga
    24901 ctatagagca actgattaga atcaaataat tcttttaagg caccactata atctccaata
    24961 taaatttcct gataaggagt cactaaaaga ttaattccta ataataataa ataggggaga
    25021 aaaaagacta gaaaagaaga aataattgca gtactaccta caatagccag atacttcttt
    25081 ttagaaattc ggcacaattg tgctgttaga aaatgactct cagcatcctc tattatctga
    25141 ctagaatagg gcagtgtaca gataagtgca gctactaggc taatcggtga aaatcctcga
    25201 atagaagaag cggcaaaaaa aatcgataaa ccttcaattt tataaatacc attgaaagca
    25261 aggaaatttc ctaaactcat gcaaagaagg gtcaaaaata aagacatata aaatcgaggt
    25321 gattgaacga ctcgtacaag attacaaatg aaaaattcca tccttactcc tccttataat
    25381 aaaaataggg tgtagcattc ttttttcatg ctacacccac aatcaaccat ctttaaggct
    25441 tactctgaca agtaagttaa taagaatctg gactccaaga acctgaagta tgaattctta
    25501 catgatttcc aaattgtggc gccatagcta atctagtacc agaaccaata taattgtcac
    25561 cacctccatt atagtacatg acaatcctag agccagaccc caatgaatat accggggtaa
    25621 tatctgaccc actataggcg ctacgaatag aggtatttaa ccttttaccg ccaccagtgc
    25681 tgtcactatt attaattcca gcagaggcgt tttctttctc aagctcacta gttgtatccg
    25741 aaccccaacg cggcaacgtt aaatcataat ttccaatctg tctagctaaa actgtaggga
    25801 gaaacaaact agatgcaatt gtaactacgc aaaaaaggaa tatatttttc ttcttttcat
    25861 gacatcgtcc tcttaagaag tgataaacaa gatagttgat tgatcaattt gatacatatt
    25921 acattttcat tatatcaata aaagaaagcg ttgtcaatta ttttatttaa aatattgtca
    25981 tattttaaat aaaatggtaa aagagactcg gtagcctcgt ctctctttat cttactgacc
    26041 taaccttctt gccaattttc ttggtcttct ttaaagcgtt ttagaagatc aaggccctct
    26101 ggcgtgatgt aaccttcttc ttgggctaga tggataagct ctctatagtt tgaaagcgtc
    26161 acaagtttaa caccagcatc tgcaaagttc ttatctgctt ttggcaattg gtagctgaaa
    26221 atcgctacaa ctccaagtac atctgctcct tctcgcttgg ctgctgctac agcttcaaga
    26281 actgaaccac ccgttgaaat aaggtcttca accactacca ttttttgacc ttgagctacg
    26341 cgaccttcga tttgattacc agctccgtgg tcttttggtt tgctacggat gtaggcaaaa
    26401 ggcaagtcca tcttatcagc aataatggct ccgtgtggaa tccctgctgt tgcagttcct
    26461 gcaatcactt ctacttcagg aaaggcttct ttaatagctt ccacaaaacc attttcaatt
    26521 agggtacgag tttctggata ggctagtgtc acacgattat cagtgtaaat cggtgacttg
    26581 ataccagatg cccaagtgaa gggttcctct ggtttgaggt aaacggcttg gattttcaag
    26641 aggtggctag cgatatcttt agcaagtgtc atggtattct ccttttattt ttctaatcta
    26701 gttctttaat tccagttctg tgtccattca tccttgatgg catgataagc tgcaacagga
    26761 tcctcagctt gggtaatggg acgtcccact acgatatagt cactgccgat ttgataggca
    26821 tcagcaggtg tcatgactcg tttttgatct ccaactgcaa caccagctgg acgaatccct
    26881 ggtgtcagac agataaaatc tggattggta gcctgcttga tgacttgtac ttcctgagcc
    26941 gagcaaacaa caccatccaa gccagcttca gctgtcttct tggcatagtg aatcacagac
    27001 tcttgcagac tggtttggat attttgaaac tcctgcatct gagcttctga cgttgatgtg
    27061 agctgagtta cagcgatcaa tttggcttga ctcccaagac cttcacgcgc cgccttcatc
    27121 atctctacac caccagccgc atggacatta gtcatatcga caccaagctg agacaagacc
    27181 ttcatggctg acttgactgt attaggaatg tcatgaagtt tgagatccaa aaagacacta
    27241 tgacccaaac cttttaagta ggacacaatc tcaggccccg ctgcgtaata aagctccatc
    27301 cctaccttga gataaaggct ttcttctgct gggaaaagag ctaaaaattc cttgaccgcc
    27361 tcaaaactag gaaaatcaag agcaatgatt ggacgatgtt ctcgcatagg tttctccttt
    27421 tacctttact agtgagagag tctggccaac agaagccacg aaaaaaggaa cctgccaaca
    27481 gcaaggttcc acgaaaaatg ggtagtctcc accctttcac cgtctaacct tagctgcctc
    27541 tctggactgc tttaaaggtt ttctattatt ctattatttc tactagcact tgtcaagtaa
    27601 aaacttagtc acgtatgtgt tgactgctat tgaacacctc acaagactct ttccaaaaga
    27661 atagttaaag actttcactt aggacagaga aaaagagttt gcttgttacc ctttaattga
    27721 acaaatggga attctgtttt attttgcgga tgcctattca tcttggcaaa ggggaagtaa
    27781 tgagaatgcg aatggacttc ttcgtgagta ttttcttaaa ccgatttggc aacaattacc
    27841 gaaaaaatcc ttaatggtgc tttgctagct tattaatcac cgtccccaaa aatacttgga
    27901 ttacaagaca ggttttgaag cacttataga ggaaatttaa aaatgttgca ttttttattg
    27961 caatttatca gttatcttat cacccaaaac ttctgcaatt agtatgagca ctattgttat
    28021 ttttcttttt tcgtacactc aaatcaaaat atagcaataa gactattctg tagaattgct
    28081 gtcaaaaaga tcagttcatt tttccttccc acttgtgttt ataatcatta aaataactca
    28141 attaagaaat tttctttttc ctaatagtta tcgtaattaa agttaataga agaacaatcc
    28201 aaataagtag tgttagatta ggaattagag ttttattcca tgaaaatccc tcccattttg
    28261 tgaaaaactt agtaaacagt cccataaaac tataatctgt tatcttcgca actgtcttat
    28321 ccaaaccaga tagcatcggt aagaaagcaa ctaaaatcat agcaggaaga ctgataacct
    28381 gagctactac ttggctcttc gcggttaaac ctatcaataa atagaataaa atgatggata
    28441 aagaggttag aagaacgatt gtaatataat taaaagtatg tacaattgta actcctaaaa
    28501 taagaggagt agttcccata atcacaaaag ttagcaaaaa aggaagaaac atcgttgata
    28561 aaatgtattc ggatccttta acaccactca acagaagagt ttgtaaattg tacttttctt
    28621 tttcttcaga caagataata gttataggac ttccaacagc caaagccaaa gaaaaaggta
    28681 aacacatcat caaaagaact aatgcctgtt gatcgttgac cttcccctgt gtttccataa
    28741 gatatttata aaaatatgtg aaagcaaaag gcactaaaac ttgcaataaa atactcttat
    28801 tggaaaggat aatttgacaa cgcaaccata ccaaagccag aaaccgttta agcatttagc
    28861 tttcctcctg ttaatgtgat aaaaatatct tctaaagtag gctcacatga atgaattgaa
    28921 aaaatatttt ccagatcagc ctgagatacc tgttctagtg atgtaaaatc aaaagttatc
    28981 tgattcccat tataatctgt aaccttaatc tttttatctt tattatatct ttgaatgagt
    29041 tcagaaggag ctccttgctc aactaatttc cctttattta ataaggcaac ataatcacat
    29101 aaaagagttg cttcattcat atcatgagtc gttagaaaaa tcgttgtccc tgctgttttc
    29161 aattctaaaa ttaactcatg aattgttcga gaagttgtgg gatctagacc tgaggtcggt
    29221 tcatccagaa agagtacagc gggtttgttg ataagagctc gtgctaaaag cattcgttgc
    29281 ctcattccag tggataattt tcctgctacc atcttgcgac tatcatataa tcctactcgc
    29341 tttaacaaat tatcaacacg tgatttacta atattataaa atttactata aaaaagaaga
    29401 ttgttataca gagacatttt ctcataaaat ccacttgtat cgctaaccaa tccaattctc
    29461 tttaattcac cgcttgttaa attttgagat ttttgtccca aaataataga ttgtccttta
    29521 tcggcaagga actgcccagt cagaatatta atcgttgtgg tctttccaga accagatggt
    29581 cctaaaaatc taaccttctt taacagtgaa gcttatatta tttaaagcta ttttatcacc
    29641 aaaacttttt gataaatggc taacttcaat catactcatt gcacctcctt tatattctac
    29701 atttttactt aacatctatt tacttatctt tatcaaataa acgtcttaaa aaaaacaata
    29761 acattaagca tataaccgtt agcaagattg tttcaatatt attgataata cgatacattc
    29821 tcaagcagta taaaataatt atatatatgc aaatgctcat tatacctatt tttttaaaca
    29881 tactaagcct ccttgctaaa taataaagtt atataataac taagacacac tatacctaac
    29941 ataataaata tccactggta actgaataaa tgttctaaaa ttaacaagca aaaataaaat
    30001 ctcaaacgat gaaaaaagcc atactatatt ttccaatgat gtttgaatat ttttattgta
    30061 gtaagcataa tatatagcaa aaataatacc caagaacaat actattaatt gtgtttctat
    30121 aacagtgaac tgcccaatag cagataaaaa agctactcct cctgataata agcaaaaaca
    30181 aactgaacga ataaatgttt tcgctctaat attgttatct ttcactttat tattttttta
    30241 caaattggac attctccgtt ttccagaaca tatttttctt gacttagagc atgatttctc
    30301 atattataaa cgtaagcgtt atctattagg atttcattat aacatcccag aaatatttta
    30361 attattaaat tagtcattat ccctcccaaa atagcaggca tctctggtgt agtcggccac
    30421 tttgtcttat cagataaagt gtacttattt atatctttgt ttatattccg acaaccaaag
    30481 caagaaccga tggtagggat atatattatc agtaataaga tagcatccat taaaccctcc
    30541 tgatatgtag gatatcttat gcgatacagc aaattgattg acaattttta taatatcaat
    30601 gggcgtatca attgctttaa cgataaaatc tatactccca tattccgcaa caattttttc
    30661 taattcttct actgaagaaa ctttaataga aataggtact acctgaacat ctgaattata
    30721 cttgtgtatt ttttcagaaa gaacattaat cttctcctta ccaacatccg actctgtata
    30781 aagaatttgc ctatttaaat ttgatggttc tattatatcg taatcagcga caataagttt
    30841 cctcactcca tacatactta gacttagaga tatataacat cctaaggctc ctgctcctaa
    30901 tactaatact gttttattct gtattttatt atactcttca ttataaaata acgaatagta
    30961 acctttagtt ctagaatatc tactatcaat atctatctca tccgaaatta aaatttgttc
    31021 atttaatagt tcaaatgtta gtttactgcc taatacttct tctatctcta atagttcctt
    31081 acaactatta aatagatcgt tgataaattc ttgcgaaatt tgaggttcta tagctatttc
    31141 ccgcatactc cgaccacgca aatacattat accttctttt ttataagcaa aaacataact
    31201 atttacgtag aacatatttc gtccttcctc tcatatataa tatagaaagc agtatagaaa
    31261 caaccacccc tcctatacta cgaacaataa tattaggtgt caaaaactgt aatagttgac
    31321 tcaaagggaa ataaataata acaaatgcta ttaaaagttg aactatatat tgaaaattca
    31381 agttattatt gttagaattc aagtatctta aaataatacc actatcatac tgaaaaaaag
    31441 gaattgaatt aataaaaatc atacctaagt taatgataaa aaataagagt ccaagcaatt
    31501 tatacgatgt gaacaataaa acaagtaaac ctgtaagtga taaaatcgaa tttgaagcaa
    31561 ttcctgctaa cataattttc aaaaattgtt ttttattttt taagaattgc accccactta
    31621 aatctacaaa aaaaagccaa attaaacaaa agtagcatta ttccacaatt tgggatctca
    31681 atttgataat tattagcaat tattgcatga ctaaattcat gtatcgttgc agacataata
    31741 acaacaagca accaaaataa aagaatgttt agcgttattg gaaagttttg gaaattagtc
    31801 aaaatatccg ccctataaat atacataata aaacattgca aaataagagc caatgggaaa
    31861 ataccaaata ggattttttc aaaattctta ttaaatcttt tatagtttaa tttttcagat
    31921 aatgttatat taaagtccca agatatttta aaaatattta tcttttttcg tgatttcata
    31981 gaatctataa gtcccatttt actaagaaca atataaaatc ttaaataata tttcttccct
    32041 actaacacta ataagtccga tatggtaaat tcttgaccta ttagttgctc taaccatttt
    32101 tttcctgttt cccaactaat acatgtttct tactagatgg tatatataga tgatactgtc
    32161 cctcataagg agtaggtaat atcttaatct tatcaacaat tctcataaca aacctaacct
    32221 ttaataaata aaagaggggc taagtaaaac atactctagt ccctcagtcc gcaatcaata
    32281 aaataatgac taattctatt aatctcttgc tgcaagacta atacggaaaa ttcaaatgac
    32341 tgtctaaaat gaaattgaaa aagcttgatg ttagtaaatg aacaaacttc aacaaccagc
    32401 aagagcaagg attgctaaac caaatccgat acctgttgca agtccagctg aaaaatcact
    32461 aactggtact gaaatttctt caatttcctc aaataaaaag ttatcttgca tgattatcac
    32521 tccctatctt tttaacaaca ggctattcca attaagagaa ctaccccagt tccaagtaaa
    32581 actcccccaa aaattcacca tctgtagggg ctacgatttc ttcaatttct tcaaataaga
    32641 atgcttcatc tgacatatgt gttaccttct tcataaaaaa ttattttgta atcgattaca
    32701 ttgcaaatgt aacataaaga aaaacagatg tcaaatatta aacgtaagaa catggtcact
    32761 aaagaactat aagagaaaag gtaaacctag cgacgcgatg agcgctgggt cgtttgattt
    32821 cgattgctct cttcctcttg ttttttctgt tcttcttcct gttttttctc ggcttccttg
    32881 gcctcttgtt tggctttttc ctcagcctcc ataattaatt tatccgccac agtgtaactg
    32941 taaattccag cttccatgtc gaccacactc ggttctgaca attgtggctt aatcttactg
    33001 taatatggca gtttcttact catttcagat agaggaacca agacttcgtc cgaatcattc
    33061 atggtcaatc gaattaaatc ggatgtcacc ttgcttgggg ctaattccac cttttggata
    33121 gccgccttga gttctgggct aatttgagca agttctgaga caaaaacctt gatttgttca
    33181 ctatcattaa agagaactga taaataagtt tctggtaaac tgttcagact cacagaacta
    33241 gtctcaagct gaccactgga aagaatagga taatgatttt caccagaaat atagtaggcc
    33301 acaatatcat attccttgac cttaatagtg aacttagttg gaaattgata gacaagttga
    33361 gctgattcaa cccaatagtt agacttaatc tgcttttcat attttgcctt gtctagcaga
    33421 aggttaatcg tataatccga atcctgaatg cctgaagcct gtcgaatatc atcagctgta
    33481 gtttgcaccg ttccctcaac acgaatatct ttcatggtcg cataaggact gagcaagtag
    33541 gcagagacaa tcaataaaag cagacttgga aataaaatcg tgaaggctcg caagatatgg
    33601 ataccaggaa tctttgcttt ggctggtttt tcctttgtag cctttttaga aagcttttta
    33661 tcctgttcct ccttctcttt agactctggt tcttctttct cttctttctc tttgtcagcc
    33721 tctgaggatg ctactttttc ttcagactct tccttagctg attctgaatc ttcctggtct
    33781 gtttcactct cctggtcctg tttgtcctct gacttctcag attcttctcc cattcgagct
    33841 tgtctttcct tttccttctc ctcagctaga gccgcctctt cttcagcctt cttttttaga
    33901 tattcttggt ttcgtttctg ccattctgat aactctttca attcttcgag gatttctttg
    33961 tcctcatttt tcttatcttt tgacatttac tttccttatg ataaatcttt tttcaacaat
    34021 tgataaaaat ctgctagaga tttcaattcc ttagaagcct tcatcttagc ttggtaatct
    34081 tccttgtgac ttagtaagtg agaaagcttc tcttccaaac tatccaaggt caaatcgctt
    34141 tcttgaaggt cttctgcata gccttttttt acaaagtaag ctgcattttc aagctggtca
    34201 ccacgactag cttcacgacc aagcggcaca atgacatgca attttgctat cgccaagagc
    34261 tcaaaaatcg tattggcacc acctcgtgtc acaacaatat cagccaattc catcaagggt
    34321 tgatagagat cggtcacata gtcaacacga aaaagatttt ggctcaactc attcaggcta
    34381 gaatctccag ttagattgat aatattgtag cgctctgtta gttctttctt atggtctgtc
    34441 accaattggt taaagacacg agcacctgca gaaccgccaa caaacaatac agtcggcaat
    34501 ttatgattaa agtggctttg aatatccacc aattcatctg gttctggatt tttttgatct
    34561 gaaaccttgg ccactgctcc cacatgctca accttagaca aactcgaagc ttgctcaaag
    34621 gttgaataca tcttagtcgc aaatttatag gcgattttat tggccaagcc catagacagg
    34681 tcagattcgt gaataaagac aggcactcct gacacacgcg cagcgataac aggcggtact
    34741 gagacaaagc ccccctttga aaaaagggtc tgtggacgaa gtcgcaacat gataaagagc
    34801 gattggacga ttccccagca aactttgaag acgtccagca tattttgcca agagaaatag
    34861 cgacgcaatt ttccagtcgc aatagaatgg aaggtgacat ccaaacctga cttaaggatt
    34921 tcttggtgtt cgataccacg cttgtccccg atatagtgga cttcccaacc atcttcgatg
    34981 aacttgggca ttaacaaaag attgagggta acgtgtccaa ccgtcccccc acctgtaaag
    35041 acaatttttt tcatattatt cttttaactc cgctactgtg tcgataaaga ggtcgccacg
    35101 tacttcaaag ttagcataca tatcccagct ggcattggca ggactaagaa gaaccacatc
    35161 tccttgagtc gcaagctcat aggccttgcg ggtcgcatct gcaatatctg tcgcctccac
    35221 ataagcgaca ccagccttgt ctgctgcccg tttgacacgt tctgcagatt gacccaggat
    35281 gaccatcttc ttgagtccag taatgtctgg caccaattcg tcaaactcat tgccacggtc
    35341 caaaccacct gcaatcaaga cgaccttgct gttatcaaat cctgacaagg ctttttgagt
    35401 agccaagata ttagttgatt tactgtcgtt atagaattta acacccttga tgtcatccac
    35461 aaactggaga cggtgtttga caccaccgaa ggctgaaaga gtttccttga tggtttgatt
    35521 gtccacacca cgaagcttgg ctacagcaat agtcgcaagg gcattttcca cattgtggct
    35581 acctggaaca ccgatttcat tcgctgccat gactacttca ccacggaagt agagttgacc
    35641 atcttccaga taagctccat caaccttttc aagtgttgaa aatggtacaa cagtggcttc
    35701 tgtcttggaa gtcaagtctt ttgccaagtc ttgattaaag ttcaagacaa ggaaatcagc
    35761 tgctgtcatc ttgttctgga tattccactt ggctgctaca tattccgaaa atgacccatg
    35821 gtagtcgata tgagttggca tgaggttggt aataaccgca atctctggat ggaattcttg
    35881 aacacccatg agttggaaag aagaaagttc cataacaagc gtgtccttat ctgatgctat
    35941 ttgagcaacc tgactagctg gatagccgat attccctgat aaaagaccat gttgcccagc
    36001 agcagtcaaa acttccccaa tcatagtcgt tgtggttgtc ttaccgttcg atcctgtgat
    36061 accaataatc ggtgcttctg aaatcaaata agccaattcc acctcagtca agactggaat
    36121 tcccttggcc aaagcctttt caatcatggg attgttgtag gggatacctg gatttttcac
    36181 cataagggca aactcttcat ccaagagttc caaaggatgg ccacctgtaa tgaccttgat
    36241 cccttcttcc agcaaacttt gggcagctgg attgtcctcg aaaggtttcc catcatttac
    36301 tgtcacaatg gcacctagct tgtccaacaa acgagctgca gattcaccag acttggccaa
    36361 acctaaaaca aggactttct tatttttaaa ttgatctatt actttcatgt ctcgaactcc
    36421 atttctactc ctactatttt accattttta tggaaataaa aaagccacaa agtgtgtttg
    36481 tgactctttc ttctaactga atcttaccat atcatctatg tgataaatcg gtaactcgaa
    36541 tgacctgatc cacttgttcc caaataagag gattgtgggt cgcaataata atggtccgat
    36601 tcggattttt taaagattct aggatggaaa gtaattcctc agagtttttg gggtctaagg
    36661 aagtggttgg ttcatctgcg aggatcaaag gtggatcctt taaaattatc ttcgctaatg
    36721 caacacgttg tgcttctcct cctgataact caaatatagg ttgcttcaaa tccaaataag
    36781 agaggtttac acagtttaga gcttgtttca tcaaagagat tttctctttt tccttcaact
    36841 ttttaccaac taaacccaga ttgagattct ctttgacggt ttggctttca attaagccaa
    36901 aatcttgaaa taagtatccc aagtaatctc taaagaaaac agaaggcttg atgtccttaa
    36961 gagaagtacc atcatagatg atttgtcctt tgtcatatgg ctctaatcgt ccaatcatat
    37021 tcaagaatgt tgtcttacca cagccacttg taccgattaa ggcataaatt ttcccacctt
    37081 caaaatgaag atttgtatct gaaaatagct gacggcttcc aaatttttta gatatattct
    37141 ttagttcaat catcctattt tcctttcata attgtcatag aaacacgaga ttctttctgc
    37201 gcttgacggt aaagcgtcag aactgcacta gctagaaaga ctaataaagt gagcaagcca
    37261 atcaccaagt ctcgactgct taaaataaag agactagcac caaatacaaa actggcaaat
    37321 tgactaacca tatactgagc atgtgtttca aaaaatcgta aacctgaaat tcgtttaatc
    37381 aaaatatctc ggcggaattg ctcgaaatat agaagattga cagaataaaa tagtaataag
    37441 gaactagcta tccccacaat agctcctaag attaaagttg ctgtttcagt ttgaacttca
    37501 ttataacgag ttagataaac acttcttcct tctttaagat aggatacttg ctcataaatt
    37561 ccagctttct tcaagagttc tagcccactc tcatatcctt tgataaagag ttgttttcca
    37621 gcattgatag accaactaga taaggatata aaactatcac ctgtagaagt cggcgtgaat
    37681 accactaaaa tcggatcagt caaatactga gtagatacgg gattctcacc gttattataa
    37741 acaaaccgct tttctcccat tgaaagataa ctaacgtgcg ctttcatctc ataatccaaa
    37801 ggagcacttg cctcctcacc agattttcca taataactca atctttcttc aaaaactttc
    37861 ttaagttctg cttctcgaga gcgcaaatgt tctgggagca agaggataaa ctcacctttt
    37921 tggagatggg ctaacttctg tttggtctca gcatctacca cgaccttttc cttgtccaaa
    37981 taactgggac taacatagag cgtattagca tctggactat aggtatccag tgtctctccc
    38041 tgttcatttt ttccttgtgg attggcaaaa tggagcagat tatcctttac ataaagagct
    38101 tgttcttctt cgattgcttc cttggcaaag gcataccact tgctctgatt ttctgtatct
    38161 tttcctctat cacctaagcc aaaagaaatt tgataatagt ctgctctatc ctgccatgct
    38221 tgttttgaaa tttcaagttc tttcaatcgt tggtaagaca tcaaacctgt cttaacagcg
    38281 tagcctactg taaagacagc aaccaactga cacaataggg ttaaaatcat caggcgttta
    38341 aggggtaatc tccccttaat aacgggaact aatgctttgt aactcaaact cattagataa
    38401 agaagcatta gtaaaattga aatcgccaat aaaaacaaca gatagaaact aatcccaaaa
    38461 ccataggtgg ctaacaagat aggataaaac aaaccttgac taaaaagaac gactccccca
    38521 cctaggaagg aaaggagggc tgatagaagg agccatttga tatcagtaga taaagaatgc
    38581 cccatgatgg ataagagagt ctgaccagaa aagagtttta tacctgctgc tctcatttcc
    38641 ttaatccgag tgataatcac taaagcaaag aaagataagc caaatattgc taaactaatt
    38701 aaaataaggg gatttagtaa tattcgaaaa gcaagaaaat agggcggtat ctttcggtca
    38761 gcacttgctt tataacccaa atctcctaat ttatcggcaa gcttttcttt cgtcaaggag
    38821 cctgacaaaa ggagataact atttagcgga tcactacgtt cacgactttc ttggctagct
    38881 tcttggaatt cttttggtaa agttccctga ccataagttg cataagtaaa gtgagtcgtc
    38941 ccatccttac tcggctctac aattcttcta gctattaaac tctgttctga gtttgcaaaa
    39001 ttctccaatt cctgttcaaa tacctcacgc gtcggttcct gagtatcttt tttgacacga
    39061 agtaaagaaa cggaatcata gcttgcatat aaatattgtg gcgcacgtaa gacaataatc
    39121 caagcaagga agaagctgag aaaaaaagtt gataataata tgaatagttt cttcatagta
    39181 gactccttgt aaacaaaatt ccccctgtaa tttcttacaa ggggaacgat ttaaatcaat
    39241 gaacgattag tcataatcac agtaaaatgc tacttgttct ccccatttag tccaaatcca
    39301 tgcataggag gtttttccag cagaagcttc tcctttatct gaatgactat tccatctact
    39361 tacaagagaa gaataatgat attttttacc atgatagtaa tttgaaaaag cccaaccacc
    39421 tcctgaacct tctccatacg tccatactcc tccatctgga tattgtacag cagctgatgc
    39481 agctcccaat aatgtaaaac ttgaaataag agctagagca agtaatctat gttttttcgt
    39541 tttcatttta ttttttcttt caaaaaaagc acaccttgag caacaatgca acaaaataaa
    39601 ccctcctctc tcttttgttg aaaccgcttt cttatgtgat aaaaatatca tttttattat
    39661 ttgttgtcaa ggaaaaaatc gaatttttta gatattttac tacattgcct ctatgaataa
    39721 tattatatag tagttttatt ttaaaataat atgcaaccag tactaaccaa atataaaata
    39781 gatgccatta acgaatttta ttcaagtttt tcccattcat actatccaag caaaagagat
    39841 gatgttatag tacaaaacaa ttcaaactat tgtaaaattc ctagcaaaaa agagagccaa
    39901 aactctcttt tttatcttct tttacttttt ttgactggca tgagtgtaat gtctctaaca
    39961 ctaaagtaag ctaggatcaa catggctatt gctaggaata tttctgttgg taattgaaaa
    40021 attttcagaa aagatagaac caataaaatc aagagtgcca ctaaaataca taccatagcg
    40081 acgatattga ctgtcccttt aatgctttct ggtgtcgcaa atacatagag taggagcagt
    40141 aaaattccta ggactaaata gaccatcttt ctctctttct agctcttatt cagctgattt
    40201 tttcttcttg ttagctttct cacgctctgc tttgttaagg atttgtttac gcaaacggat
    40261 agactcaggc gttacttcca tgtactcatc gtcgttcaag aactcaagag actcttcaag
    40321 tgtcaagata cgaggcgtct tgataacagc tgtttggtcc ttagtagctg aacgaacgtt
    40381 ggtcatttgt tttgccttcg tgatgttaac tgtcaagtca ttttcacgag agttttcacc
    40441 gatgatcatt ccttcataaa cctcagtacc tgggttgaca aagatcgtac cacgttcttc
    40501 gatagacatg attgagtaag ttgtagcctt accagcatcg atagaaacaa gggcaccacg
    40561 gtgacgtcca ccaatttccc ctggaatcaa tggcaagtat tggtcgaagg tatggttcat
    40621 gataccgtaa ccacgagtca ttgacaagaa ctcagttgag tatccaatca aaccacgcgc
    40681 tggaacaagg aagaccaaac gagtttgacc attaccagtt gaaatcatat ccaacatttc
    40741 acctttacgt tcagaaaggc tttggataac agacccttgg tattcttctg gagtgtcgat
    40801 ttgtacacgt tcaaatggtt cacatttaac accgtcgatt tcttttacga taacttctgg
    40861 acgagatact tgaagttcat agccctcacg acgcattgtt tcgataagga ttgacaagtg
    40921 caattctcca cgtcctgaaa cagtccattt atctggtgaa tcagttgggt caacacgaag
    40981 ggaaacgtct gtttgcaatt ctgcctgcaa gcgttcttcc accttacgag aagttaccca
    41041 tttaccttct ttaccagcaa atggtgagtt gttgaccaag aaagtcattt gaagagttgg
    41101 ctcatcgatg tgtaggattg gaagagcttc tactgcatct gtcggagtga tggtttcacc
    41161 gacaaagatg tcttccatac ctgaaacggc aatcaagtca cccgctttgg cttcttggat
    41221 ttcacgacgt tccaaaccaa agaaaccgaa gagttttgta acacggaagt ttttagttgt
    41281 accgtcaagt ttagaaaggg taacttggtc cccaacctta actgtaccac ggaagacacg
    41341 accgataccg atacgtccaa cgaagtcatt gtagtccaaa agtgacactt ggaactgcaa
    41401 aggctcatct gagttatcta ctggagctgg gatatggtcg ataatcgtgt caaagattgg
    41461 tgccatagtc gcttcttggt cagctggatc atctgacaat gaagaagttc cgttgatcgc
    41521 tgaagcataa accactggga aatcaagctg gtcgtcatct gcaccaagct cgatgaaaag
    41581 ttccaagact tcatccacta cttctgctgg acgagctgat ggcttatcga ttttgttaac
    41641 aaccacgatt gggacaaggt cttgttccaa ggcttttttc aatacgaaac gagtttgtgg
    41701 catggttcct tcataggcat ctacgaccaa gacaacaccg tcaaccattt tcatgatacg
    41761 ctcaacttct ccaccaaagt ccgcgtgtcc tggtgtgtcc ataatgttga tacgagttcc
    41821 gttgtaagca acggcagtat ttttagcaag gatggtaatc ccacgctctt tttcgatatc
    41881 gtttgagtcc atagcacgct ctgccaattc agtacgtgca tcaagcgttt ctgattgttt
    41941 caataattcg tcaaccaggg ttgttttacc gtggtcaacg tgggcgataa tcgcaatgtt
    42001 acggatatct tctcttaatt ttgtcatgat ttcctctata atattcaaaa tttattttct
    42061 aactgaacga ttataccata atttcaaata aataacataa ctcaagcaag tgtaaatgtt
    42121 ttcactccgc ttttcttttc acgtcaagcc ttttcaaagc aagcgactta tgataagata
    42181 ggcacagtat gcgtttagat aatttattag cccaagaaaa agttagccga aaggccatga
    42241 agcaagcact cctcagaggg gaaattctag tcgatggttg cccagcccga tccctagctc
    42301 aaaatatcga tacaggacta caagaactcc tttttcagga tcgaatcatt caaggctatg
    42361 aacacaccta tcttatgctt cataagcctg ctggtgtcgt tacagccaac aaagacaagg
    42421 aacttccgac cgtcatggac ctgcttccat ctgacatcca gtctgacaag ctctatgccg
    42481 ttggccgact ggaccgagat acaacgggac tcctcctctt gaccgataac ggtcccttgg
    42541 gctttcagct cctccatccc caatatcatg tcgataagac ttaccaagtc caggttaatg
    42601 aacttctaac acctgaccat atccaagcct ttcaaaaggg aattgtcttt ttagatggta
    42661 ctgtctgtaa acccgcaaaa ctagagattc tatctgcaag tccctccctc agtcaagcct
    42721 ctatcaccat ttcagaagga aaatttcatc aaatcaagaa aatgttcctc tcggttggtg
    42781 ttaaggtgac tagcctcaaa agaatccaat ttggggactt cacattgaac ccagatttag
    42841 cagaaagtaa ctaccgccct ttgaaccaaa aagagttaca aatcattaaa aactatttag
    42901 agatgagtcg ataaaacaaa aaaagcttta aaactaaagc ttttttcttt tatttaccga
    42961 aaaattaagg cgattgctac aatccagtta actacagaaa tcacaattcc taagatatta
    43021 agaatctttt ctattttata gtctaattgt gactcttttt ggtatgaaat agccaagacc
    43081 aatcctatga tacccaaaat caagcctaca attggaaata acaaaccaag aataatcgac
    43141 aagataccca caaaaagtgg atttttcttc ttttctttca tgttctaaga actctttaaa
    43201 ttttatacaa attaattata ctataaaaca atagcttcat cctatcattc gactaatttg
    43261 gaaataaggt tagctagtct tcactttccc tttccaagaa tccaagccat aagaaaggat
    43321 ataaatctca gaaaaacctt gttttttcaa gtaaagagct gcatttgtaa ctcgttgcgc
    43381 acgttggttc tcgtagagaa ggacaggttt atctttacga agggctgcaa gactagtttt
    43441 caactgactt gaaggaatat tgcgtgcacc aaggatatgt tttctgtgga attctgctgg
    43501 gtcgcgcaaa tcaatcaatt gacccgtacg aatcaaggct tcaaactcct cattgtccac
    43561 aattttagcc gcacgacgaa tacgaagata gttaaagccc atccacgcca acattgctag
    43621 tataagtgcc cacaaaatcc aagtaaccat tagttctttt ctccattttt ctcaatataa
    43681 tccaattcta ccttgtgctc tctgcgaaga actgcttctg cctctagata gtctaattta
    43741 tccatcaacc ctgcatcgta aatccgagat agttccaact tcatcagttc aatatcatat
    43801 aagcgttttc ccatgtaaac aataatacca aatcgtttga ggaattgctg cacatcatag
    43861 aatgttttca taagactcat tctagcaaaa ttttgtgttt ttttcaagaa gagactcaca
    43921 caatgctcct tattttccta tcttctttgg cgattctaag gcaagtgtgg tacaataaaa
    43981 acatgagaat tcaacaatta cattatatta tcaaaatcgt cgaaactggc tctatgaatg
    44041 aggcagccaa gcaactcttt atcactcagc caagtctttc caatgctgtg agagatttgg
    44101 aaaatgaaat gggcattgag atctttatcc gcaatcccaa gggaatcacc ttgacccgtg
    44161 atgggatgga gtttctctct tatgcccgtc aggttgtcga gcaaactcag cttctggagg
    44221 aacgctataa aaatcctgtc gcccaccgcg aactctttag cgtttcgtct caacactatg
    44281 cctttgtggt caatgccttt gtctctttgc tcaagaaaag cgatatggag aaatacgagc
    44341 ttttccttcg tgaaactcgg acttgggaga ttatcgacga cgtcaagaac ttccgcagtg
    44401 aggtcggggt cctcttctta aacagttaca accgtgatgt tttaaccaag atgctggatg
    44461 acaatcacct actagcccac catctcttca cagcgcaacc gcatatcttt gtcagcaaga
    44521 ccaaccctct ggcaaagaaa gacaaggtga aactgtctga tttggagaat ttcccttacc
    44581 tcagctatga ccaagggacg cacaactcct tctacttttc agaagagatt ctttctcaag
    44641 aacaccacaa gaaatccatt gtggtcagtg accgtgccac cctctttaat ctcttgattg
    44701 gtttggatgg ttataccatt gcgacaggga ttttgaacag caacctaaac ggagacaata
    44761 tcgtttctat cccactggat attgatgacc cgattgagct ggtctatatc cagcatgaga
    44821 aaaccagcct atctaagatg ggcgaacgct ttatcgacta tctactagaa gaagttcagt
    44881 ttgatagttg agaaatgata agaaccaata tgtaggctag caacaacctg cacattggtt
    44941 ctttttactt ataattaaaa gtttcccctg ccaacttatc agctagcttg ggaaagagag
    45001 tataaaactt atgggctagg ttcaacaaaa tcgggagatt gagttctcgt ttattttttc
    45061 ctataatctt gacaatcttt ttagccactg catctgcctc taagaggaag cggtcaaccg
    45121 atttaagata agttccatct gggtcagctt ggtcaaaaaa tcctgttcgg attggacctg
    45181 gattgactgt tgtcacatag actccatagg gcataagttc gagtcgcaga gcatttgaaa
    45241 aaccaatagc cgcaaacttg gtcgctgagt aaagactaga cttgccagta gctattagac
    45301 ctgccatgct gacgatgttg atgatatgcc ctttgctgct ttccttcata cgagccgcaa
    45361 ggtgacgaga cagattcatc agggcaaagg tattgacctc aaacatctgg tgaatatctt
    45421 tatcagcaat ctggtcaaat ccctcaaaaa tcccgtaacc agcgttgtta atcaagacat
    45481 caatcttgcc atagcggaga taaagatcag ttaccagagc ttctagggct gaatcgtcgg
    45541 taatatcaat ttcaatcaat tctgcatggg aataatttcc gtagagttgg gctaattttt
    45601 ccttatttct accaagcaag atgagttggt cattgggcag gagtttgacc atttcttgag
    45661 ctagaccacc gctagctccg gtaatgagaa tagtaggcat acttatcctt tctgtgactg
    45721 ctagatttcc acttcttcca agtctttgac cacatggaca ttttcaaaaa ttgtggcagc
    45781 gtccttcttg agtttgctta tatcttttga gaggaaacgg gcactgatat ggttgagtag
    45841 gaggcgtttg gcacctgctt ctaccgctac ttgtgcagct tgcatattag ttgagtgacc
    45901 atggttacga gcaatttttt catcaccctt gccataagtg gactcatgaa ctaggacatc
    45961 tgcattgaca gccagacgca cactggcatc cgtttttcga gtgtctccta aaatagtgat
    46021 aatcttacct ggacgtggcg ctgagatata gtctgctgcc ttgatttcag ttccgtcttc
    46081 caaaacaaga tcctggccgt ttttgatttt accaaaaagc gggccgaacg gaacaccagc
    46141 agccttgagt ttttcagcat ccagcgtccc ttctagatcc ttttgcatga cacgatagcc
    46201 aacacagaaa atagtgtggt ccagctcctc tgcatacaca gtgaatttat cggtttcaag
    46261 aattttaccc agagaatctt ggtcaaactc atggaaatga atgcggtagg gcagacgaga
    46321 acctgacaca cgaaggctgg ttaagacaaa tgacttgatt ccttgaggtc cgtagatttc
    46381 caaatctgtc tgctcttcat tggcctgaaa ggcacggcta gaaaggaaac ctggcaaacc
    46441 aaaaatgtgg tctccatgca gatgagtaat aaagattttg ctgaccttac gtggtcgaat
    46501 tgtggtttcc agaatgcgat tttgcgtacc ttctccacag tcaaagagcc aaacttcgtt
    46561 aatctcgtcc aaaagtttca gggcgagact tgaaacgttg cgggctttag agggctgacc
    46621 agcccccgtt cctaaaaatt gaatatccat tcgatacttt ctaattaatc aatatataac
    46681 atggctgtgc ggttttccga tcggaaatag cgtttgccag aaaaagcagc agcttcttgc
    46741 aataaatcct cttggctgta gcctttgaga cgttttcgac catcagccaa tctttccaaa
    46801 tcagtcaaag ctgtgagact ttctaggctg acaacttcct cgtccttgac aggcttcatg
    46861 taaatcttac cagactcttc aaagactaat tgatgggaga aaatttgcgc aatttcaaag
    46921 agcaagtcat ccgagatttt ctcctcattt tcagagaaaa tccgaccaaa gccgtcactc
    46981 tcataacaaa aaccaaagga tttaccagac agattaagcc gaataaaagg cttattttct
    47041 agggtgaaac ttggctcagt attgtaaaga ttcagttcct gactgagttc tgcaaaataa
    47101 tccgtcgcag cctgaggact ttttttctga tagagttctg caaagtaggc attaacaaca
    47161 cttggcggag gtgtaataag tgttaactgc tcctgctctg ttttaccagc tagaagctga
    47221 tccagataga ccttgtccag acttgtataa cctccatact ttagagccaa agttttaata
    47281 tcagtcataa aattcttcta acctccattt atttttctcg gaaatgtagc ctgtaatcac
    47341 ttcgccgtct tcctgataat cacgttcttc cagaattgca acactctcta aatcatgaat
    47401 cttgtaggac tttgaaaaag gcactcgcag ggtaaatgct tcaaaaattt ccttaatctt
    47461 atctagcaat aatgcttgca agttttcacg actgtcctca gacttggcag aaatgagggt
    47521 atatggcgtt tgggtaggcg tgaaatcctc caccaaatcc gctttattat aaagcgtcaa
    47581 gtgaggaata tcttccatgt ccaggtcttt catgatggag agaaccgttt tttcatgctc
    47641 ctcgtggtaa ggattgctag catcgataac atgaaccaga aggtccacat gcttgctttc
    47701 ttccaaggtt gacttgaaac tggacaccaa ctctgtcggc aaatcttgga taaagccaac
    47761 agtatctgtc aaagttactt ggagattgcc tcccagatga atactcttgg ttgtcgcatc
    47821 cagagtcgca aagagctcat ctgcttcata ctgggtctta ctggtcaaga tgttcatgat
    47881 agttgatttc ccagcattag tataaccaat caaaccaatc ttaaaagtgc tagactccaa
    47941 acgtttttct ctgacagtcg cacgattttt ctcaaccacc ttaagctggc gctcgatatc
    48001 cgtgatttga ttgcgaacgc tacgacggtt cagctccagt tggctttcac caggaccacg
    48061 ggaaccaatt ccccctgcct gacggctgag cataatcccc tgaccaacca agcgaggcaa
    48121 gaggtatttg agttgggcta ggtggacttg gagcttccct tcatggcttc gagcccgcat
    48181 ggcaaagata tccaaaatca actgcatacg gtcaatgacc ttaacaccga gaacttcctc
    48241 tagattgaca ttctgccttg gggtcagacg gttgttgacg atgacagtag tgatttcttc
    48301 tgcatccacc ataagcgcaa tctcttccaa cttaccagag ccgacgaagg tcttggaatc
    48361 atatttttca cgtttttgtc tgtagctatc tacaacgact gcccctgccg ttttcgctaa
    48421 actagccaat tcttccatgg agaggtcaaa actgtccata ccctgcaatt ccacaccaat
    48481 cagcaggact cgctcctctt ttttctccgt ttcaatcatc taaaaactcc tctatctggc
    48541 ttaaaatgcg gtcttgtaca ccagattctc caatctgata aaaggtgacc tgcatgcgat
    48601 tacggaacca ggtcagctga cgcttggcaa aacgacgggt cgcctgttta agactctcac
    48661 gagcttcctc caaggtctgc tctccacgga aataaggaaa gagttcctta tagccaattc
    48721 ctttagcagc ctgtacatta ggggaatggt caaacagcca cttggcctca tccaaaagcc
    48781 cagcctcaaa catcaaatcc actcggtggt tgatacgctc ataaagttga ctacgttcat
    48841 catccaagca gataatcagc ggttcataca aaatctcttg attttccaaa tcctgaccaa
    48901 aatgggcaat ttctaaggca cgcatagcac gacgacgatt aaactgggga atctcaaggc
    48961 ctgcttgctc caccaaatgg gctaattcct catctgaata tggctccaaa ctagctcgat
    49021 aagctaaaat ctcctcatga ggagtctccc cacctaggtg gtaaccttct agcaagctct
    49081 ggatataaag tccagtccca ccggcgataa tggctagctt gccacggctg tgaatatcct
    49141 caatagtcat cttagcttct gaaacaaaat caaaagccga gtaagactca gttatctctc
    49201 taacatcgat taaatgatga ggaacagctg cctgctcttc tggactagcc ttggccgtcc
    49261 caatatcaag tcctcgatag acttgctggc tatctccact aaccacttcg ccattaaagc
    49321 actttgcaac ttcaatagct agagccgtct ttccaacagc agtcggtcca acaatcacaa
    49381 ttatttttgt tttcatcttt tttccttgaa aaattcccat tttttcgtta ctattattat
    49441 aacacaaaaa ggtcagtcag aaaaatgtga cctcttgagg aggctggctg attgagaata
    49501 taaaggagga agactcatgg ctaaaggatt cgctaaaggt cttgtaacag gtgtcgcagg
    49561 aactgtcgct gccgttgcag gtgcagtata cgcatttaaa aagaaagtaa tcgaaccaga
    49621 agagcaaaaa gcagctttca tcgaagaaaa ccgtaaaaaa gcagctcgtc gccgcgtatc
    49681 acgttaagaa acaaaagaag ttgggattat tctcaacttc ttttttctat tcttttaaat
    49741 agctaggtca aacttcaact gtggcttaac agggtcataa tccaccaact caaaatcttc
    49801 tgctttgata tcaaagaaat tagtcccatc aggaacattt aaaaccaagc gtggttggca
    49861 gtttgacggc tcccgacgga gcaattcctg agcttgttca aattgattat catagatatg
    49921 gaggttgttg atgaagtaga agaacttccc aaccttccag ccaaaatgtt tagcaatcat
    49981 catctgcaaa gccacatact gcatagcgtt gatgtggtgg gccaccagca tatcattgga
    50041 gcgctgggtc aaggtcgcat ccagatagat ttccccatca acacgccgaa catcaaacat
    50101 ggtctgaaag gcgcacggga gcagcccatc tgtttcttcg aaagcttggt aatcccagag
    50161 agaaataata ttgcggcggt tccaaggatt ggtttccaac tgtttgagaa gcttattgat
    50221 aatgtcgtgt ttcttaacaa cggcaccata gcgctcacca atggttcccg tgtctccaac
    50281 ttcccagtca ttccagtagt gaacattgta cttgtcatta agcacttcta agctatttga
    50341 ctggtcttgg taaatccaga gaacttcttt gatggcggat ttgattgcaa tgggacgcaa
    50401 ggttatgata ggaaattctc ctttagataa gtcgtactcg gaaaaggcac cagttacata
    50461 cttggaatta gcaacagtcc catccttgta cttaggacga gcctgctctg agaaaacacc
    50521 ttcctttaga atgcgttcaa tattctcttt aaaaatcgta tctgcttttg tcatttactc
    50581 tcacctcatt cattgtccta actagtatag cataaaaaat aaaagaggaa cattactaac
    50641 tctaggttag cattttcctc tctcattatc ttattgcaat acaagtgatg ctgctccgat
    50701 aactccagcg tcatttccta gagttgcaag agctaattta gtagatgtgc gtacttgtgg
    50761 gaaagtattt tcgtcataga ctttttgaac accttgtaga aggaattctc ccgcagctga
    50821 cacaccacca ccgatgacga ttgttgatgg gtttaggatt gaaccaatgt tagcacaagc
    50881 gattcccaag taacgtgaga agttacggta aacaatcaaa gcaaggtcgt ctccttcttt
    50941 tgcgagatca aagacagtct tagcagttac ttcttctccg ttatcaatca agcgtttcaa
    51001 ggctgcatcg ccttcgtatt catcggcata gcgacgagtc aagttgacaa ttcctgttgc
    51061 agaagcgact gtctcaagac agcctttctt accgcaagta catgagattg gctggtcaaa
    51121 gtcaacagtg atgtgaccca actcacctgc tgcaccagca acaccgtgaa gcaatttgcc
    51181 ttctgcgacg ataccgccac caacaccagt accgagtgtc ataaagacaa catctggttg
    51241 gttatcacca gcacccatcc agcgctcacc aagagctgct acgttggcat cattatcgat
    51301 gaaaaatgga atgcccaaag ctttttcaat cttttgtttg attggttgaa gggttttcca
    51361 gttcaagttg taggcaccga taacagtccc tttgtcacgg tcaaccacac ctggtgatcc
    51421 cattccaatg ccttggaagt ccgctgctgc caatccaagc aagtccaaac gatgttgaat
    51481 agactcaatc atatcatcaa cgatatgact tccctcatcc aaaatgttgg tcttgattga
    51541 ccattttcct tggatttctc ctgctgttgt taagattgca aatttgatag aagttccacc
    51601 aaggtcaatc ccaataatct tttgactcat tatattctcc tttttcattg tgtagtaatt
    51661 gaaaatgctt acagtactag tatatcaaaa tccattcact tatgcaaagg tttgcgtaaa
    51721 tgaattataa ggaatttttt cgcctaccag tatctgttaa ccatctaaat gatcaatggc
    51781 atattgagct gcatcatttg aaaatttatc aaaatcagaa gttaattgtc tatacatacg
    51841 tttttttgac atgtggaata acgaattata actttttgcc tttcctaaag cagcagaata
    51901 ttcactattg ctatcattac tagaagaagc tgtacttgct tgaccttcct tccaaactcc
    51961 gtcagcgcca acataataac gtccaccatc aacccattca ttgacagcca ttttaccatc
    52021 cgattttaga tagtaatttc cttgccatgt actataagca taagaaccat ctgatgtcaa
    52081 ataataccaa gcttgatagg tggcatcata aacccattca cctttagcca ttttaccatc
    52141 tgatttcaaa tagtagtttc cttgccatgc attgcgagca tatgaaccat ctgatttcaa
    52201 gtaataccat gcttggtaag aagaatcata aacccactca ccttgtgcca ttttaccgtt
    52261 tgatttaagg taataagctc cttgccatgc attttttgca taagaaccat ctgatttcaa
    52321 ataataccaa gcttgataag aagagtcata aatccattca ctctgtgcca ttttgccatc
    52381 agctttcagg taatagtttc cctgccatgc atttttcact agatttccat ttccatcaaa
    52441 atagtaccaa gaaccgtcct gcttaaccca accacttgct gtggatgaag ttgtatcagt
    52501 ttgagttgta gccgcttgtt ttgctttaaa agcaccctta ggagcatttt tcaattcgca
    52561 agccacacca tcatgatcgc ggtctaactt ggcagaataa ccaggttctc cctcatgaag
    52621 atccgaatat ccattagccc aagcttcctt acagctcgaa aaatggatgt tttcttccgc
    52681 caaaactggt tgtgaaaaca aggctaaaat tggcaacgtc accagactca tttttaaaaa
    52741 tagacgttta ttcatttctt tctcccataa ttatgatatc gatttcaata ttattttatc
    52801 aaacttattt cagcaattca aggaaacttc tggtcttttc tacaaactcc tttggttttg
    52861 ccttattcaa gacatgaggg ccatcaggaa tgatctgaaa ctgcgaatct gttaacagtc
    52921 tatggagagc tttcatagaa ctaagattcg gtttatcttt gctgccacaa attagtaagg
    52981 ttggatagga gcaagtccct gctatatccg ttaaatcaag tgtcttcaat tcctcagaaa
    53041 ctccgaccat aagagtcttg tctgctccct gtttttcaaa tactcttttg ggaagtagtt
    53101 taaaaatcag caactgaaga taaaatagga tattccctgc taatttaagc gggcatcctg
    53161 acagaatcaa agctcgaaga tttggtaaat cgtaactgga aagttctagt gtcagggcag
    53221 cacctaagga caatccaatc aaaacaaaag gttctgtctc ttgagctagg tgctgataaa
    53281 ctcgctcttt agcttgttga tagttactaa ctccagaagg aaataactcg atagcctcag
    53341 aaggataatc tgtcagtaga ttccgaactt ctttccaaga ctctgctgac tgccctaacc
    53401 catgcaaaaa tatcaatttc atctagttct cctcaaggct tagttcatac aagcctctca
    53461 ctgcattaca gccgtaaata gcttctgctt gggttaaatc tgccaaggtc aagactttct
    53521 cttctacctg tcctgtttct agcaaatact gacggtaaat tcctggtaag attccaagtc
    53581 ggataggcgg tgtgtagagt tttccagcga ttttcagaac caaatttcct atagaggttt
    53641 caagcagttc tcctgactta ttgtggtaaa tcttctcttg ttctcctagg ctcaaatgcg
    53701 gtcggtgagt ggttttaaag taggtaaagg attgattcaa agcagcttcc tgaaggcaga
    53761 cttgggcctg acaaaagctt gtactgagag gggttaatac ttgacgattg acttctatct
    53821 ctccagattt gctaaggctg attcgcaagc ggtaatctcg attagcttca caatcctgac
    53881 actcttcctc aatcttgtgt cccaagtctt ctgcatcaaa aggaaaagca aaataacgac
    53941 tagcttttct cagtctttcc agatgttgat cttcaaacag caggttcttc tggctgattt
    54001 cccctgtcgt aatcagttgg aagcgagctt gtttacgata aagaactgct gccttttgat
    54061 gaacctctcg gtattcagat tcccatgtgc tatcccaagt aatccctccg ccaactccat
    54121 aaatggcttg acctttgtga agttgaatgg tacgaatggc cacattaaaa atccgtcgtc
    54181 catttggaag caagagacca atcgttccac agtagactcc acgcggttga ggctccaagt
    54241 ccttgataat ctccattgtc gcaattttcg gtgcacccgt tatggaacca caaggaaaga
    54301 gtgagcggaa gatttcaaca aggtccacat cctctcgcaa ctgactcttg atggtcgaag
    54361 tcatctgcca aacagttgaa tactgctcta cctgacacag acgctccacg tgctcgctcc
    54421 caacttcaga aatacggttc atatcattgc gcaagaggtc cacaatcatc atattttcag
    54481 agcgattttt gggatcctgt tccaaccaac tggcctgttc aagatcttct tggtcagtta
    54541 ccccacgctg agtcgtcccc ttcattggtc gtgttgtcaa ctcgcgatca ttttgctcaa
    54601 aaaagagctc tgggctcatg gaaatcactg ccatctcgtc atgttccaca taggcattgt
    54661 agcccgcctc ctgctctacc accatacgat tgtagatggc aaaaggattg gcacttaact
    54721 tttgcttgag ttggacggtg tagttgacct gataggtgtc tccctgcctc aagtgatggt
    54781 gtatctgggc aatggccttt tcatagtctg ctgcagacgt cacttcctgc caatttgagg
    54841 gcaaatcaat atcctcataa gtcagaggaa taggggaagt ttctacgcta tcatgaacag
    54901 taaagtaaag caggtactct cccagtaggg gatccttgtg aactgctaat ttttcctcaa
    54961 aagcaggtgc agcctcgtag ctgacatacc ccaccacata ataaccttgc tcttggtagc
    55021 tttccacttg tgccagcaaa tctgccactt cttctacatt tctcgttttc aactctttaa
    55081 taggctgggc aaaggtatat ctctccccta aagtcctaaa atcaatcact gtttttctat
    55141 gcatacctta agtatagcat aaaaaggcag atacagacaa agctgatcta cctttttacg
    55201 attttattca ttctatgctt gtggtgcagt aaatagatca ccagagaaac cgtctgtgtt
    55261 tttaaggaga gctttaaaga ctttcgattt caagacaact gtatttcggt atttgtcttt
    55321 aatactacta tcgtttagtt ccgttaaatc tttagtaaca gcctcatcaa acatagtctt
    55381 caactgttca taggttgaaa tttgagtgcc attaatttca attggtgcaa aacctttttt
    55441 agattttgta agaacttccc cataccattg cttcttccaa tcttcaaggt ttgaaaattg
    55501 gttattagaa actttcttaa taatgaaatc atcacctaat agaccgttat tttctttatt
    55561 ggctgcacct tgatgtttgc ttgaaacata gtcaatgaac ccatgttcat atccatagta
    55621 accccacata cggaaggcgt tatgtttgaa ggatagagaa ccaggggcac cttgactcgt
    55681 attaccgcca taaataccag ccatcatatt aacattgaca tatgccgtac caaagtcctc
    55741 tgggtggaag accttattac ctggatttcc gtgaatggtc atgaaattat tatttaccaa
    55801 gtcatcgatg gtttcaaggt tagttgtttt ctcagcgtct atcaaatcac gcactttgtc
    55861 ccattggtga ggaccactta gtttatttct gtccattggt cgacgtgttt cgcgatcaat
    55921 tttcttgaac cacttactat tgtcaccttt aaccttagga agaacagcct cagcttctgc
    55981 ataatcgagc atcatcatag cttcattgta gttcttcatg taatggtcga tttggtcacg
    56041 tgtttgaagt ttggtaggat ctggattata ccattggttt ccatcatttg aacgttcaaa
    56101 tgccatattt aatccaagtg cgccatattc accttgatgt ccatgttctg ctggagtttg
    56161 taacatacct tgagcaaatg cttcaagatc tgtaccctgt cgatgtctat gacctcccag
    56221 atatgccatt cggtcattta cgtgggtagt ctcatgtgta aaggcagatg tgccatattc
    56281 acttattaaa tccgacataa caaaatatac agcatccata ggctgtggat cagcaaagat
    56341 gtaagcatac gctccatacc catacttata atcatgatac ttatcaatac gtccaaagaa
    56401 ttcacgaata ggtgcataat ccggtttatc ttttcgatga ccaaatctat caggccaacc
    56461 accgggtgca ccatgattat cccatacagg agttggaact acattttgac tcttaagaag
    56521 tttatcgcgg acattatcag tggcaaggcg tgaccaaaaa tctaagtaat taacttgctc
    56581 tttagcacgt ttattgattt cactcttgaa cgattcacgt ttttcttctg tatctttacc
    56641 atacttttca aacgaactaa atgagatagt attatatgtt gaaatcataa ataaatgtgc
    56701 atctttcaag ttcagaagcg ataaaatcat gcgtccatgt tgtccgttat taagtccttc
    56761 atatagacga tattttttat tagcaaatgc agggttagtt gacggttgtt caactacata
    56821 agcattattt tcaatagctt tcttaaacca aacatttatg tctgtttcat ttgtgaatag
    56881 tttcatattg taggtcaaga agtcatgtaa gtttccagaa agagtatttt tcgccaccac
    56941 ttcacggaag gactcctgtg tacgacttcc cttaatatag tcctcttttg aaccaatttc
    57001 tattaatcga tctaaaacac ttacattctt accataaaaa tctggtttga atagcattaa
    57061 ttctttaata ttgaagttat caaatttcac accgtaataa cgatttaggt atgttaatcc
    57121 taacaggaca gcagctttgt tatcttcaat tttcttaatc aaggcacgtt ttgcagcttc
    57181 atctgtattc agttgatgat cttcattttc aactaatttt gtcacaaatg tattaagatg
    57241 atcttttact tctttaaagc tttcttctaa gtaaagattc ttaattgcat taactctgtt
    57301 atccccagtt cttcctaatc gttgataaat tggatcagat tgtaattcaa ttggacttaa
    57361 aataccttca atagcactaa ttaaatctgc acgatcttta acaaccatat ttggtgtata
    57421 gacgacttca ccaagctctg cgacactgta ttcttttact tgcttaactt gagagtcttt
    57481 aggagaaatc gtaaagatat cttttgtctt atctgcgtaa tgaaccataa tatggtcagc
    57541 atctgtaagg tctgtaataa agtcattacc tttcattgca gtcacagaca atacttcttt
    57601 attcattaat ggactatcag ttgtaagctt gttcccttga ttcacaatcc attctttgtt
    57661 gtagaacggt tggagttttt caacattacg ataaacaagc tcacgatttg cattataatc
    57721 ttgaattgtt ttgtattctt catcacgtaa tatacggcga ttcaacttat caaccaaatg
    57781 ctcagttact tcaaatgtat cagcagtgat acccatatcc ttaattttct tatcagcttc
    57841 tacctgtgaa atttctttaa ttttagacga ttgtttatgg gttttatctc cagaactcac
    57901 accgataact gttgcattat taggtttaat ccaattgctt acaaattcat catccatatc
    57961 attagaacca aagaaaatat caccacgctt aacattcact aagctgatat tgttatcaat
    58021 ggttccccaa ggccagtctt taccaattaa accgcctaca tcacctctag caacatcaat
    58081 agtacctttg gctacagaat ttcttacatt agaccaagca ccaacatctc ttggattaaa
    58141 atcatgagct aaatgtccta ctatagcacc tgcacgagta tttaaacctt taagttcaac
    58201 atctgcataa gctttattta aattgcctcg ataaatctca gatgcaatcc cagccaagtt
    58261 ccacccttta tcaccaacag attgaacttt tccgataaaa gcaacattag tcataatacc
    58321 tgcatcatct aatttatcca aaatacccgc aacattgtta ttaccaacga tagtacccgt
    58381 tactttaata ttttcaacag ttgcattttt cactgtttga gctaatgaag ctaattgatt
    58441 tgcccaaggc atattaatat taacgttaat taaattaata tttttgatag aacccccttc
    58501 aactctatca aataatggac gagcagtgtt atgaatggag aaatgcttac catcaacact
    58561 tgttaagtga cctgtaaatt tacctgttac atatgattta cttggtgtag gtacatttgt
    58621 tgcatttaaa tccgatccta atttaaactc accgttagga tttttctgca tagcatctac
    58681 taaatctttg aagttatagt aaacgttatt ttgcgatgct ttgggtttct ctatgtaata
    58741 agtgtatgtt tgactcaaac tattatttga atcacgttgg attaaatcag gagctgaagc
    58801 agtaacttta aataaggatg tctcctcctc agttacttcc tctatattag taatggcaag
    58861 ccttgttact ttattatgat tagtggtaat ttttagataa tatgacgtta gattttctgg
    58921 aacagtttct agaaggctac tatctgtttc atttccattc tcatccactt tcatcaatct
    58981 tgtttcttta atatctttaa tctcaacttt tttaaggtct aactgaactt ctttatcttc
    59041 taatatttca gtttcttcac cgttacctcg atcatagacc atggttgtgg atagtgtata
    59101 accttgataa tatttcaagt tgtctaaagt agcttgtaag ttattttctt ctaccgttac
    59161 ttctttaaca actgttccag tattatcttt tagagctact ttaatcgatt taatttctac
    59221 tccagctggt ttagtcaatg tataactagc tgtcgcactc ttcttcaaga catctttatc
    59281 tgttttagcc cattccaagg ttggtttctc taactctttt gtgccattct taataatttt
    59341 gtcttgaggt ttttcaatca ctgtttctgt gatagtagga gcgtcacttg ttttttctcc
    59401 gcgaattgtt ttataggttt cagtaatttg tttcttatcg tttacacctt cttgagttac
    59461 ttgtcttgtt ccgcgtttta aagtgtcatc ttcttgttct tttgtttcaa aaggaatgat
    59521 ttcttctctt gtctcaaccg ttgtcccttc aattggtttt gtaccacgga ttacctgttg
    59581 atttacaggc tccttggtga cttccgtact ggttgaaaga acttggtcag ttttaacccc
    59641 tcctattgtt ttataggttg tttttgtaac ttgacttcct ttttcaccat ttcgtaggac
    59701 agtttcttcg tccgtgtact tggttgggtc ctcagtcgtt tcagttttat agtcaagttc
    59761 tgtagttgat tcttcaacga gtgttccttc agtcacctta tactcaggta attgttctgg
    59821 aacaagagcc tcacccacgt aatcttcttc ttgcgtcccc ttagctgttt tagtctcctc
    59881 ttttggttct acagtttctt cagccttggt atctggagtt gactcttctt gtttcggtgt
    59941 ctcttccgct cccctatctt ctttaggatt gtcttcttgt gatgattctt ttggtgtact
    60001 tggttgctca gcttgtgtag gttgcacggg ttgttctggg acttttgctt gttctactgg
    60061 tggttcaact tttgattcct cagctggttt gtctgatggt tgactttctg gcttaactgc
    60121 tactttttcc tctgattttg actcaacttc tccacctact tcttcaactg gagctggttc
    60181 tgctgaatct tctttcccct cttctacttt aggaagggtg tcgtcagtag gttttacctc
    60241 cgattttggt tcttcctttg gactttcttc tgttctaggt gcttcttctt ttggagtttc
    60301 ctctgtctct actacttggt tttctgtcct agcttgctcc tgatttgttg ttgattgagg
    60361 agtctcaact tcgactacag tcacctctcc aggttttgct gaggtttctt ctaaaacagt
    60421 gtccaagcca agcgttttga ggatgtcacc tgatagataa ccaacatagc gatagccatc
    60481 catttcaaca acaccctctc gactagccag cgctaaggtc gcaactgggt ctacagcccc
    60541 tgcactagga agaactacca atcccatagc tccaactaga aagacgctag caattttctt
    60601 tctcttgtag attaaaagca agctcccaac agtcagcaaa ccaaaagctg tcaaaacaga
    60661 tgcttctgtc cctgtttgag gcaactgatc tttttgatac accaaaccat atacaacttc
    60721 attcctgtca ggctttcctg tctgaattaa atctttagct tcttgtgaaa taatctcttt
    60781 atttacatag tgataggtag ctgcgtccac tacagaagga gccatcaaaa ggcttccaag
    60841 aaatacagag cctacaactc ccttaatctt acgaattgaa aaacggtctt ttttaaacac
    60901 tttcatctcc tttattcatt ctcaagactt tctaatagca tcttgcggat agtgcgcacg
    60961 cgcacctccg attaattttg gacgactagc cagtgccgtt acatgggcat gaccaatctc
    61021 tctcaaaata gggcgaatcg gaacctgaac atgcttgaca tgcatgccaa ttgcagtgtc
    61081 tccgatatcc aatccagcat gagccttgat aaattcaacc tcaactggat cctgcataaa
    61141 cttaaaggct gccaactgcc ccgaacctcc tgcatgaaga gtaggatgga cactgacaat
    61201 ttccagatca aactgctctg ccacctgacg ttcaacaacg agagcccgat tgacatgctc
    61261 acaaccttga actgctaaat ggatacctct actacctaga atacccaaga tagtctccac
    61321 tatcagctca ccaatctctt gactggattc tttcccaatc tgaccaccta gcacctcact
    61381 agaagataga cctaaaacaa aaaggacccc ctgcttcaaa ttggtctttt ctaaaacatc
    61441 ttccactacc tgacgtgttt ctctttgaat ctgtgtctcg ttcatctctg ttacctctgt
    61501 tgtcactctt ctatcatacc gttttttctt gtttttagca agatagacaa cctataaagt
    61561 ctgcccaatt acgcataaaa ctcccagaat tgactgggag ttagctagtt tctattctat
    61621 ttatatatat ttcaactttc gttccttttt ggggtctaga atcaatcttc atctggtaat
    61681 tggctccaaa atgaagtttg agccgttgat cgacattttg aagaccaact cccccacgtt
    61741 tgagttgact ttgactacta tcaccagcat cttggaagcc aacgccatca tcctcaatac
    61801 ggatgaccaa tcccgaatcc tgtttctgga cagaaagttt aatatggccc tgaccttcct
    61861 tttccttaat gccatggtaa agagcatttt ctacaagggg ttgtaggacc agcttgggta
    61921 agactaaatt atcaaaggca acattttcat taatttcgta ttccagctta tctccatagc
    61981 gttgtttctg gataaagaga tactggcgga catgattgat ttcgtcagag agacaaatca
    62041 agtccttgcc ttgattgagc gccaagcgga aataggttgc caaggacttg gtcacctgca
    62101 ccactcgctg actatcatga aattcagcca tccagatgat ggtgtccaaa gtgttataga
    62161 ggaaatgtgg attaatctgg ctcgaaaggg cttgaagttg gtactgacgg gtcgtttctt
    62221 cctggctacg aatagctacc atcaactgat caatctgatc caacatagca ttaaattggc
    62281 gagttacttc tctcagttca taggcaccaa cttccttggc acgaagattt tgagcaccag
    62341 aagcaatttc caacatggtt tctctcaaat ccttcaaagg agcaatccag cgtttaagac
    62401 tgaaccacac taagcagaga caaacaagaa gagatgtgac actggcccca agcaaggtcc
    62461 acaagagctg actccgaacc tggtctaact tttccaatga tgacacgcca agtaccgtcc
    62521 aatcagttcc tgcaatcttc tcttgactga cgtaggattt gtgaccagga gtataaccct
    62581 gacctgtctc gatgtagggt ttcatagcct ccattttgct agacgaacta taaactgtgt
    62641 gttgaggatg gtagacaaat tcatggtttt cattgataat gaaggcaaag ccctgctgcc
    62701 ccaactggag ttgattgaga taggcttcca gagtttcata agaaatatcc aaacgaagca
    62761 caccaagatt ggctcccttt gcatcaacaa gttcttgagt gacagaaatg acccactgac
    62821 tatctgattt acgagctgga gtcaaaacag gcatagctcc ctgatgaata gccttttggt
    62881 accaatcctc agccatcata tcagaggaag ttttcatctg cacactgtca tctgtagaaa
    62941 tgacctgacc agatttggtc accagcacaa cagttttcaa gtccttatct gacttcaaga
    63001 tggtcaaaaa caaatctcgg attccctcga ccttgtcttg actgggattc tcagcatagg
    63061 ccagaacatc cgtctgctgg gtcaaaccag tcgaggtggt ttctagtttt ttgatataag
    63121 actgaataaa gtggctagtc tggctgatgg tcgtttggct gttgccctca atggtggcct
    63181 caatggctga agaacttgat tgatagtaga aagttccaac cagagctagg agaatgagaa
    63241 agaccagaaa gatggaaata accattctaa ctaaaagaga agaacgcttc atcggtcttc
    63301 tcccttctta aactgacgag gtgtcacacc tgcaatctgc ttaaaacgtt gggtaaaata
    63361 gttcatatct tcaaaaccaa ccttctctgc gatctcataa atcttcagat ctgtagttaa
    63421 aagcaagagc ttggcttgtt taacacgttc tctcaccaga taatcctgaa aaggcaagcc
    63481 caactctttc ttaatcaagg aactcagata ggtcggacta aaacctaagt cactggctaa
    63541 agactttaaa ctaaattggc tatcagccag atgagactgg attttctggg ccatgtttcc
    63601 ttcaaaccta ttagtcaata aatcttgtaa ctgctcttct ttctcttcct tgtctagttt
    63661 ttgtttgatt ttccccaaca tttcctcaat atcctgacga gaaaagggtt tgagcaggta
    63721 gtcgtccaca cctagtttga cagcagacaa ggcataatca aaatcatcgt aacctgttaa
    63781 aaagaccaaa tgaacctgag gataggtttc tcgtaccaga ctggccaact ggatgccatt
    63841 tagatgaggc atgttgatat cggttaaaat gatatctggc acctgctttt ggatcaattc
    63901 ccaagcctgc cttccatttt cagcctgacc gatgatttcc atatcgtagg ctgctacatt
    63961 gaccagttta gtcaaacctt gtcttaccag atattcatct tctacgatta agattgtgta
    64021 ggtcatgctc tgctccttta ccacttacta gtatcagtat agcaaaattc tcctctaact
    64081 gcttaggaaa gacctcttat actcaataaa aatcaaaaag taaactagga agatagccac
    64141 aggtttctca aagtatagct ttgaggttgt aaataaaact gacgaagtca gctcaaagta
    64201 tagctttgag gttgta
//
LOCUS       DAVBEM010000006        51676 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVBEM010000006 DAVBEM010000000
VERSION     DAVBEM010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51676
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.006"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(54..362)
                     /locus_tag="VQ548_000396"
                     /pseudo
     CDS             complement(54..362)
                     /locus_tag="VQ548_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            complement(604..900)
                     /locus_tag="VQ548_000397"
     CDS             complement(604..900)
                     /locus_tag="VQ548_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653312.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(884..3043)
                     /gene="pfbA"
                     /locus_tag="VQ548_000398"
     CDS             complement(884..3043)
                     /gene="pfbA"
                     /locus_tag="VQ548_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HET2653313.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVISTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKESVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(4173..5399)
                     /locus_tag="VQ548_000399"
     CDS             complement(4173..5399)
                     /locus_tag="VQ548_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HET2653314.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVFEVGPGDEVIVPAITYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(5442..6134)
                     /locus_tag="VQ548_000400"
     CDS             complement(5442..6134)
                     /locus_tag="VQ548_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET2653315.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGNLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSTEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFKVLK"
     gene            complement(6320..8071)
                     /locus_tag="VQ548_000401"
     CDS             complement(6320..8071)
                     /locus_tag="VQ548_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2653316.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALVDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(8061..9806)
                     /locus_tag="VQ548_000402"
     CDS             complement(8061..9806)
                     /locus_tag="VQ548_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2653317.1"
                     /translation="MSIIQKLWWFFKLEKHRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSPAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTELRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSEVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILNPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(10012..10308)
                     /locus_tag="VQ548_000403"
     CDS             complement(10012..10308)
                     /locus_tag="VQ548_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HET2653318.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(10461..10917)
                     /locus_tag="VQ548_000404"
                     /pseudo
     CDS             complement(10461..10917)
                     /locus_tag="VQ548_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            11051..11878
                     /gene="xth"
                     /locus_tag="VQ548_000405"
     CDS             11051..11878
                     /gene="xth"
                     /locus_tag="VQ548_000405"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HET2653319.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11890..12033
                     /locus_tag="VQ548_000406"
     CDS             11890..12033
                     /locus_tag="VQ548_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET2653320.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEYQRSEENFLFLLK
                     SVN"
     gene            12033..12272
                     /locus_tag="VQ548_000407"
     CDS             12033..12272
                     /locus_tag="VQ548_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET2653321.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRPLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      12656..12751
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            13151..13732
                     /locus_tag="VQ548_000408"
     CDS             13151..13732
                     /locus_tag="VQ548_000408"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HET2653322.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13732..14994
                     /locus_tag="VQ548_000409"
     CDS             13732..14994
                     /locus_tag="VQ548_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HET2653323.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LSAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(15081..15947)
                     /locus_tag="VQ548_000410"
     CDS             complement(15081..15947)
                     /locus_tag="VQ548_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HET2653324.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEEIKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(15934..16704)
                     /locus_tag="VQ548_000411"
     CDS             complement(15934..16704)
                     /locus_tag="VQ548_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET2653325.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(16730..17584)
                     /locus_tag="VQ548_000412"
     CDS             complement(16730..17584)
                     /locus_tag="VQ548_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HET2653326.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYLNNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(17741..18145)
                     /locus_tag="VQ548_000413"
     CDS             complement(17741..18145)
                     /locus_tag="VQ548_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HET2653327.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVRI"
     gene            complement(18215..19696)
                     /locus_tag="VQ548_000414"
     CDS             complement(18215..19696)
                     /locus_tag="VQ548_000414"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HET2653328.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIVYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSADHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEHVGILLD"
     gene            complement(19715..20893)
                     /locus_tag="VQ548_000415"
     CDS             complement(19715..20893)
                     /locus_tag="VQ548_000415"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HET2653329.1"
                     /translation="MAQHLTTEALRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVFENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            21058..22065
                     /gene="galR"
                     /locus_tag="VQ548_000416"
     CDS             21058..22065
                     /gene="galR"
                     /locus_tag="VQ548_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HET2653330.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFRNYSQAKGIYHDELVFQGN
                     FTAQSGYDLMKEAIQNLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHDRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(22111..23148)
                     /locus_tag="VQ548_000417"
     CDS             complement(22111..23148)
                     /locus_tag="VQ548_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET2653331.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAVEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLQSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(23149..23502)
                     /locus_tag="VQ548_000418"
     CDS             complement(23149..23502)
                     /locus_tag="VQ548_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET2653332.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(23746..24636)
                     /locus_tag="VQ548_000419"
     CDS             complement(23746..24636)
                     /locus_tag="VQ548_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HET2653333.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            24769..25305
                     /locus_tag="VQ548_000420"
     CDS             24769..25305
                     /locus_tag="VQ548_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET2653334.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(25472..26278)
                     /locus_tag="VQ548_000421"
     CDS             complement(25472..26278)
                     /locus_tag="VQ548_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HET2653335.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(26623..28143)
                     /locus_tag="VQ548_000422"
     CDS             complement(26623..28143)
                     /locus_tag="VQ548_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HET2653336.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLVQKEKENLVIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGKTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMEPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(28136..28864)
                     /locus_tag="VQ548_000423"
     CDS             complement(28136..28864)
                     /locus_tag="VQ548_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2653337.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            complement(28879..29643)
                     /locus_tag="VQ548_000424"
     CDS             complement(28879..29643)
                     /locus_tag="VQ548_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HET2653338.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVVDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(29647..30090)
                     /locus_tag="VQ548_000425"
     CDS             complement(29647..30090)
                     /locus_tag="VQ548_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2653339.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKFQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(30772..31068)
                     /locus_tag="VQ548_000426"
     CDS             complement(30772..31068)
                     /locus_tag="VQ548_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET2653340.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(31090..32154)
                     /gene="pepA"
                     /locus_tag="VQ548_000427"
     CDS             complement(31090..32154)
                     /gene="pepA"
                     /locus_tag="VQ548_000427"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HET2653341.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            32555..33256
                     /gene="galE"
                     /locus_tag="VQ548_000428"
     CDS             32555..33256
                     /gene="galE"
                     /locus_tag="VQ548_000428"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET2653342.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            33679..34638
                     /locus_tag="VQ548_000429"
     CDS             33679..34638
                     /locus_tag="VQ548_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2653343.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKEISESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLGFILLLWRGGRKDAD"
     gene            34628..35584
                     /locus_tag="VQ548_000430"
     CDS             34628..35584
                     /locus_tag="VQ548_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HET2653344.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLTLQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            35581..36333
                     /locus_tag="VQ548_000431"
     CDS             35581..36333
                     /locus_tag="VQ548_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2653345.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGS
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            36429..37394
                     /locus_tag="VQ548_000432"
     CDS             36429..37394
                     /locus_tag="VQ548_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2653346.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPAILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(37619..37861)
                     /gene="yidD"
                     /locus_tag="VQ548_000433"
     CDS             complement(37619..37861)
                     /gene="yidD"
                     /locus_tag="VQ548_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HET2653347.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(37861..38583)
                     /locus_tag="VQ548_000434"
     CDS             complement(37861..38583)
                     /locus_tag="VQ548_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET2653348.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(38570..39139)
                     /locus_tag="VQ548_000435"
     CDS             complement(38570..39139)
                     /locus_tag="VQ548_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HET2653349.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKSQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(39158..39886)
                     /locus_tag="VQ548_000436"
     CDS             complement(39158..39886)
                     /locus_tag="VQ548_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HET2653350.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(39886..40626)
                     /gene="xerD"
                     /locus_tag="VQ548_000437"
     CDS             complement(39886..40626)
                     /gene="xerD"
                     /locus_tag="VQ548_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HET2653351.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(40617..41078)
                     /locus_tag="VQ548_000438"
     CDS             complement(40617..41078)
                     /locus_tag="VQ548_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2653352.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(41075..41596)
                     /locus_tag="VQ548_000439"
     CDS             complement(41075..41596)
                     /locus_tag="VQ548_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET2653353.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(41572..42543)
                     /locus_tag="VQ548_000440"
     CDS             complement(41572..42543)
                     /locus_tag="VQ548_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HET2653354.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGKSSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(42540..43334)
                     /gene="racE"
                     /locus_tag="VQ548_000441"
     CDS             complement(42540..43334)
                     /gene="racE"
                     /locus_tag="VQ548_000441"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HET2653355.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIYVEHVEL"
     gene            complement(43541..43789)
                     /locus_tag="VQ548_000442"
     CDS             complement(43541..43789)
                     /locus_tag="VQ548_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HET2653356.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(43931..45556)
                     /gene="treC"
                     /locus_tag="VQ548_000443"
     CDS             complement(43931..45556)
                     /gene="treC"
                     /locus_tag="VQ548_000443"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HET2653357.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTGNGIGDFRGIIGKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCIGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKDINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(45734..47701)
                     /gene="treP"
                     /locus_tag="VQ548_000444"
     CDS             complement(45734..47701)
                     /gene="treP"
                     /locus_tag="VQ548_000444"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HET2653358.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGNDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            47886..48596
                     /gene="treR"
                     /locus_tag="VQ548_000445"
     CDS             47886..48596
                     /gene="treR"
                     /locus_tag="VQ548_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HET2653359.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            complement(48629..49432)
                     /locus_tag="VQ548_000446"
     CDS             complement(48629..49432)
                     /locus_tag="VQ548_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2653360.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKHLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKLKLLLLDEHTAALDPKTSQMVMDLTQKIVEYHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(49445..49873)
                     /locus_tag="VQ548_000447"
     CDS             complement(49445..49873)
                     /locus_tag="VQ548_000447"
                     /inference="COORDINATES: protein motif:HMM:NF014684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653361.1"
                     /translation="MKTEIGLVLRSTGDNIPMSEANGVNVNTMKIVGYMISTGLIALC
                     GSLFAQNDGFSDVTSGTGTIVVGLSSEVLIHDLTIGGRLLSIGIGAIVYRLIILNIYE
                     IPNLDQNLVRLFNAILLALVLFAPALQKRLKIRGLKLRNE"
     gene            complement(49882..50322)
                     /locus_tag="VQ548_000448"
     CDS             complement(49882..50322)
                     /locus_tag="VQ548_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2653362.1"
                     /translation="MNFVLSSLSEGLLWSIMAIGVYLTFRILDIADMTAEGAFPMGAA
                     IVVSQIQAGANPWLATLLALLAGMVAGLISGMLHTKMKIPALLTGIVTLTGLYSINIK
                     IMGSVPNLSLGDSATVFKQLASLGLTNEGAVFSLSLVCLLLVWF"
     gene            complement(50367..51272)
                     /locus_tag="VQ548_000449"
                     /pseudo
     CDS             complement(50367..51272)
                     /locus_tag="VQ548_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512061.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
BASE COUNT        15175 a        11736 c         9477 g        15288 t
ORIGIN      
        1 attaaaaggt taagtaattt ttccaaaata cagcactcat atagacagta tcatcaatta
       61 tagccattgg gattttttga ttgccaattc catgtatctc tacacatgtc ttcaatcgat
      121 tttgttgtcc tccaatttaa ttccttatat gctttgtctg catttgcata ataagttgca
      181 acgtctcctg aacgtcttgg aactatttta taaggaatag ggatcttatt aacactttca
      241 aatgtattta caagttgtaa tacactagtg ccttctcccg agcctaggtt atagatataa
      301 acatctgttt tttcagatac tttttctaaa gcttttatat gtcctattgc taaatctact
      361 acttgaatct tttatctcat ttttcccttt ttcaaataag ttatctactc tatgatcagt
      421 tatttccatt tcgtttacta acatgacgca gtcacctagc atcatatact ccaacttttt
      481 ttctgaaagt ttagcaaata ttggtaagcg ataatatagt atattgaaac tagaatagta
      541 cacctctact tctaaaacat tgttagaaat cgatttgact gtcctgattg atttgtccta
      601 ttattatttc attttactat actctgttaa ttcatatgag tttaaaccga tttcatcttt
      661 aacctcgagt aaagcagttt caaatatttg tttaagagtt tttgattctt tacaattaac
      721 cgacaaactt tctgataaaa tatgtacaac ttctgagact gaataaccta tctcctcttt
      781 agaattatat aaatctgtag ctccaccaat aatccaaaaa tactgatttt gtgaacctac
      841 aatatcctca ttttctacgg aacttccttg tatcgaacaa attttattta tctttaccat
      901 aatacttcaa cccttttagt gtcaaaagta aaccaattcc tgtcactgtt aagaatagtt
      961 ccataatctt gttcgaacca gtctttggta atttttgttt tacatctact atttctttag
     1021 atttattaat atgattttca gtttctctgc catctccaac tattttatag tttacttctt
     1081 ctgtcttatt atcttgttta ttgtcgatct tgtcattcat ttgtctatta tctttacttg
     1141 agttaaactc tccgttcttc tggttactat caattacatt atttgaatta gattgttttt
     1201 cctctttgtt tttttctttt tcgtttttat cacttaaatt atttgttaca attttgtaaa
     1261 gcccattctc cgttacaata ttgaaattac catcgctatc acgtataaca gattctttcc
     1321 catttgcatt agatttgatg aatgatatat acttaccgga taaattataa aattggttat
     1381 ttaaaacggt tattttaccc tttgaatcct caataacaat tccttcttta ccaccgaata
     1441 tactattctc tgagactact aaattatcac taactcgtaa taattcaata tttggttgtt
     1501 ctgtttcctt agaattatta ttaattacat tttttgttac agtaatatct gatacttttc
     1561 ctaaatattc tgcactatct tttgcaactc gtatcgcttt tgttttagga tcggcaatat
     1621 taaatatatt ttcggcgata accacctgtt tatttaaatc taataggtct ttagtgtttt
     1681 tatagctata agcatttact aaagctgctc cgctttctcg ataatgtaca ctctctcctt
     1741 taactttctt atcaaagcga tttcctttga ttaatacatc agtgaatcct gtaaaacgta
     1801 cacctgcata catcatgtta tcaaaatgat tatttaaaat tttaatatta gaggggttct
     1861 gtgtcgacaa tgtttgatag tgtgtgccaa ttgctgttac taattcccca gatttatcac
     1921 ttttgccaaa ataggaattt tgaatagtca cattttcaga ttttttccca tcatcattca
     1981 aggcataagg aaaacctttt ctagttaatg gttcaatctg aatgctctcc ttacttatga
     2041 tttgcccatc cttcatcgtt ttgggtaagg cttgcccaag aaaacgagaa ttatcaacta
     2101 atacattttt cgaacctgca atttgaatag catgcccttg ataactatcc ttgaatgtta
     2161 cattttttat agttacgtta tttgaattcc caatagcaaa tgcacctgaa gaatttataa
     2221 gtggtagatt ttttgcttta gttccttctt cattcaaagc accgttcata tcaatcgtac
     2281 caccagaata actaatatct tctgttgggc cccattctac ttgcgcacca tcatccgtaa
     2341 ataaacctgt cataaaaaca atggaagggt gattcttaat atttatacca tttagaattg
     2401 tagctttctc attcaattct aagtgtgtat gactttttaa aaaaacaatt tcttttacta
     2461 aataagttcc ttcaggaaaa tatacatttc ctccacctag cccttgagct gcagcatcta
     2521 ttgcatcttg aattgcttgt cgatcatcat gaatcccatc acctaccgca ccataatctt
     2581 ttacacttaa agcagtatct tcaaattctt ttttgataat tctgtcactt ataacatctt
     2641 ccttataact cttattttca ttagtagata ttactgtaga ttcaactgtt ctgttgtcta
     2701 attgtgaatt ggaacgaata gtaccattag agctgatact attaacactt aacgaattat
     2761 ctaaaccatt agtggttgaa ttagaggcaa tcatttcagc agaacgattt tgattaacag
     2821 ttggtgaatt atctaaatca ttagtgattg cattagaaga ctcttttgta gccatcggtg
     2881 aagaactagt aacaacttca tccgataaaa taccttggct tcccaaaatt gaaattgcca
     2941 atagtaccga gcaagtcccc acctttaatt tacgaatact gaatacctca ttaggaacaa
     3001 aatatttcat cagaacctcc aattttttta ctatttttaa caattgatta ttacttttct
     3061 taaaatagat agaatgacac cgctgtcatt atctttatca tatattttcc aaattgaatt
     3121 gtcaaggaat aacacaagaa aatattaaaa tttatactct tcggaaatct cttcaaacta
     3181 ggtcagtgcc gccttgccct aagtctaggt tactgacttg gtcagttcta tagtagactg
     3241 aaactataat agtacacctc tacttctaaa acattgttag aaatcgattt gactgtcccg
     3301 atcgatttgt cctattctta tttcatttta ttatatctac aacctcaaag cagggttttg
     3361 agctatctat ggccaacttc ctagtttgct ctttagcctt ccattcaaaa gtgatgctat
     3421 ctttcttagc ttgaatataa aatatcccat ttactatatt taaatttgtt gatatgttgt
     3481 aaattataaa tgaaagaaca aatatcttgt catacaagca ttcgccaggg atatttacat
     3541 gaatatcgct catatggcgg attgaaacta aaacactaca atatatttct taaatagacc
     3601 ttctataaaa gctagattta acctcgataa aaatagatgc agtgcttcta aaatactgga
     3661 atagggcata taggtaatcg tagacaagtg ttttatagat tgtctcgcgg gagatctaat
     3721 gatgtatagc aagcatcact aaacatatag aatatttgtg ttattataat gtcaatatgc
     3781 tataaattct atcatgcaaa agaatgacta gaacatgaaa gacaggcaca aaactttgaa
     3841 caatattctg aaaacaaaaa aagacgcgag tttccacaat ctcactcatg gaaactcacg
     3901 tctttcaaaa aatagggtga attaaaaact agaacaagac actagatttt ctaaatgatg
     3961 tctagtaagg attctaaatg ctacaccaaa ttgctcacat cttatttcaa accacgggac
     4021 tcccacaaga aaggaaaatc ctataaaaat tctctctctg aggagagaga ggcctcaact
     4081 acaggtgtaa actattatca attgaaaaca acagttttta cactcaatta gactttttag
     4141 ggacaggatc actttcgctt gactgtagtt tgtcattttt ttgataaagt tagcactttt
     4201 tcagaaactg ttttgaaagt ctcaatgata tagtctactt cttcatcgct taatttagta
     4261 tgaagaggga gggtaatttc attctcaaag aaggcatagg ccttaggata gttcgtcata
     4321 tcaaatccaa gattcttata ggctgtcaag agaggaagcg gtttgtagtg aacattactt
     4381 gcaattcctg ctttagccaa ttcttggatg atgaggttgc gttcttctag gcttgctcct
     4441 tctacacggg tgatgtagag gtggcgtgaa gattcgacag tttcagtctt gtgtgccaaa
     4501 ggatggatgc gagaacctgc aaaaccacta tcatagcggt ccacaatgtc cttacggcgt
     4561 tgcaacaaac ttggatagcg gtccaattgt accaaaccaa gtgaagccat gatatcggtc
     4621 atgttgcact tataggctgg tgtaacgata tcgtattccc atgaccccag ttgcatcttg
     4681 gcaagagcat ccttagtttg cccgtgaagg gaaaggattt ggaattcctt gtacatctct
     4741 tcgtcatcaa tcactggatt ggctttccaa gtcgcacttc caccttctgc cgttgtaaag
     4801 ttcttaacgg catggaatga gaaggaagta aagtcagcga tagaaccaga aggttgtcct
     4861 ttataagtag atcccaaagc gtgggcacta tcagagacaa tgacaatacg gttaaaggcc
     4921 ttttgccact tgcttgaagc ggtaaagaag tcacgttttt tctccacgac ttggaacaaa
     4981 cggtcataat cgcaaacaat ccctgcgagc tctactggga taatcacctt agttttctca
     5041 gtgatagctt gctcaagcag gtcatagtcc atctcaaacg tatctgcttg gatatccacc
     5101 atgacagggg ttgctcccac gtgcgtaatg acactacatg aagccgtata ggttatggct
     5161 ggaacgatga cttcatcacc aggtcccact tcaaaaacgc gtaaaatcaa ctccagagcg
     5221 gctgtcgcag agttgagaca aacagtctta ggtgtctgtg tgtaaagaga caagcggcgc
     5281 tccagttctt ttgttttagg acctgttgtg atccaaccag aacgcagggt atccgctact
     5341 tcagcaattt ctgcttctgt gatatcaggc ggtgaaaatg gaatattgta atttggcatt
     5401 gatttgctcc ttttatctgt actcattctc ttatgactac tttattttag taccttaaac
     5461 acggtttgaa acatgatttt gatgtcccca aagaaactaa actctcggag ataggcgagg
     5521 ttatagcgca tcttttcagg aagaacatgc tccacatagg cctgatcaac tgacagacct
     5581 ttctctgtca tttgactgat gatggtgtcc tcatccttgt agttgatgct ggctggagag
     5641 gtaattcctg cttgcaagag caaggttgcc atcatttcag tgctatactg ctctgtataa
     5701 cgtggcactt caggtcgtgt accgacaaag gacatctcac ctttaaggac attgaccaac
     5761 tgaggcagtt cgtccaaacg gacacgtcgg atgaaatttc caaccttggt aatacggcta
     5821 tcgttagcag aagtcaccag atttcctttt ttatccgcat ccgtcaccat ggtacggaac
     5881 ttccaaatct tgaaccgacg gttgtactgg gtcacacgct cttgcttgta aatcactggc
     5941 cccttgctat ccaacttgat ccaaatgctc aagatgagaa agatgggaga ggtcagaacc
     6001 agtaagacca aggccaaaac ccagtccaag caacgcttga aaatcagcga acccttcctt
     6061 ttagagacaa gctggtagta agactcaacc tcgcttgatt tcatttccac aggcaagtct
     6121 tcccatttca gcatgctgtt ctcctttgtt tttattatac tatttgtcaa cactttttgt
     6181 caacactttt cattatacca caaaatggaa aaggcggtga aaaaaatctg taatttgaag
     6241 gatttccttc tagtactcaa tgaaaatcaa agtacagctt tgagattgca gataaagctg
     6301 acatggttta aagagatttt caaagagtat aggccatggc ccctgcctgc aaactataca
     6361 tcttgtgata ggttcctccc agagccaaga gttcctcatg ggttccactc tcgataatgc
     6421 gtcccttatc caagacatag atgcagttgg cgtcttgaat agtagaaagg cggtgagcta
     6481 tagcaatagt tgttcggccc tgtctcatct tcgccagaga agcttgaacc aagctttctg
     6541 tttcagagtc aatattggct gtcgcttcat ccaaaatcag gattttaggc tggctggcga
     6601 ctgttctagc aaaggcaaga agctggcgtt gcccagtaga gaagctcgaa ccacgctcgg
     6661 aaacagggga gtcgtacccc tgaggaagtt cttgaataaa ggaatctgca tccacaaagg
     6721 ctgccgcagc ctgaacctgc tcatcactga tttcttggta catggcgata ttggacttaa
     6781 tagttccatg atagaggaag ggttcctgca agaccaaacc gatgtttttt ctcagctctt
     6841 cttgactgaa atccctgata tccacatcat ccaagagaac tctccctgac tggaattcat
     6901 aaaagcgcat gaggacattg ataatagacg atttccctga acctgtatga cctacaaagg
     6961 caatggtttc acccttatta acagagaaag aaatgtcatc cagaatcgga tgtttaccgt
     7021 catatgagaa acacacatgt tcaaagcgga tattgccttc ttggactttg gcttgcccat
     7081 tttcttgaag aggttcatag gtcctctcgt ctaccagggc aaagacacga cctgcagaaa
     7141 ccatagacgt ttgcagtgtt gaaaagtttt gcgtcacctc aatcaaaggg tcaaagaggc
     7201 ggttgatgta ctggataaaa gcatacatgg tcccggccgt tatcccgata gaaagaccac
     7261 gatagccaaa ataggccatc aagacagcat aacctagaag tttcaacaaa ctcatggcag
     7321 gtctcaaaaa gagggcatcc aaggctacag aacggttggc atagaccaag tgctcttggt
     7381 tgatttcatc aaattctgcc tgcaggcgct tctcttgatt aaaggcctgg attattctga
     7441 ttccctcgat gttttcagcc agcttgctat tgatatctga caagagactt ctggttttct
     7501 caatgatttt cactgatttt ttccgataga gattgaccaa aaggaaaatc aaggggagaa
     7561 agagcaagac taatgctgtc aaacgaaaat ccaataccaa catggtataa agggttgtca
     7621 gaaagatgaa aactgctgag ataaagctag ataaaatccc agaaaacata tcactaatcg
     7681 tctcggtatc gttggtcaaa cgagaaacga tagaacctgc tggcgtcttg tcaaagtaag
     7741 acatgcccag tttctccata ttggcaaagg catcccgacg aatatcccta acaatactgt
     7801 aagacacgcg cgcaaagaga agattgccga catactgaac tacagtttgt aggatgtaga
     7861 gaccatagta gaccagcaaa acggtaacgg ctagttggtt aagattgctg agatactggt
     7921 cgataaagtg ggaagccacg aggggtatga cacttttaat gaccgtcgtc gctaggagaa
     7981 aactgagtgc caaaaaggtc aggagtctat aaggcttgag ataagacatc aagcgcttca
     8041 atacagccca ttgttcttgt ttattctgca tcttcttctc ctttcatttc taactgctga
     8101 gactggtagg tttgggcata ccagccatcc atcgctagca agtcttcgtg cctgcctcgt
     8161 tcgataattt gaccattttg tagaactaaa ataaaatctg catggacaac agcactgagg
     8221 cgatgggcag ttataatggt tgtcttgtcc tttcgcgtct ccttgagatt gtcgataatc
     8281 gcatactctg tcttggcatc tacggcggat aaggaatcat ccaaaatcaa gatatcaggg
     8341 tttaaaatca tagcccgact catagccaac cgttgctttt gaccaccaga aagactgact
     8401 cctttttcac caatcagcgt atcaaatcct tgaggcatgt ctacaatatc ttggtaaact
     8461 cgggctagct tagtagcttc ctcaacctct gaaaggggca agttaggatt gccaaagcgg
     8521 atattgtcta ggattgaagt cgcaaagaga aactggtcct gaggaacata gcccatgaga
     8581 ctgcgaagtt ctgtcaaacg atagtcccga atatcgtgac cgtttagata aatggcaccc
     8641 ttatccacat cgtattcacg caagaggagc ttgattaagg acgttttccc agagcctgtc
     8701 tgcccaacca agcccagtgt ttgccctttt gccaaactaa agtgaatatc cgtcagtgtt
     8761 tcctcatttt caaaagcaaa gctgtcaatg gcatactcca aacgcccatt ttcaatacca
     8821 tccagaggaa actcagggtc ttgtacagga gattcctgag acaaaagatt ttcaatccgc
     8881 tggtaagaaa ccttccctcg ctgagtagta ttaaagagga agccgatggc cataagaggc
     8941 cagaccagca tatccaaata gctgataaag gtgactagat taccaactgt aatctgccct
     9001 tcctgaacca tcaaggagcc aaccaaaagc gttaaaacat aggacgaacc aacaaacaag
     9061 agaaccatag ggtcaaagag actatcatat ttcatggttt gcaggttctt ttggaaggtt
     9121 aattcattga ctgcctgaaa agacttcaac tcgtctgcct gataaccgaa agacttggtc
     9181 actttgatac ctgatacgga ctcctgtacc ttgttattga gttcagaaaa agcagcttgg
     9241 gattcgccaa aggccttatg agtctttctc cctaggcgac tagtcgcata ggccatgaaa
     9301 ggtaggggga gaatggcaac aagagtcatc tgccatgaga tgctaaagag catggtcaac
     9361 aaagtcacca gagccgtgat agaggcatcc accgcagaca tgacaccgcc acctgctaaa
     9421 cgagtcaagg cattgatatc attggttgcg tgtgccatca gatcacccgt ccgataggtt
     9481 tgataaaagg ctggcgacat ttttgtgaaa tgcttaaaca agcgagaccg catgatctgt
     9541 cccaagcaat aagaggtccc aaggatatac atacgccaca catagcgcaa atagtacata
     9601 ccaaaggctg caagtagcaa gtaaaatagg ctaagaagga ggtcctgctg ggttaattgc
     9661 cccgatgtga tggcatcaat gactcgcccc ataaccatag gaggaatgag attgagaacg
     9721 gaaaccaaga ccagggccac aatcccgact agataacggt gtttttctaa cttgaaaaac
     9781 caccagagtt tttgaataat ggacataaaa tccctttctg attgcaaatg gaaacctgag
     9841 gccaatactc aatgaaaatc aaagagcaaa ctaggaaact agccgcaggc tgctcaaagc
     9901 actgctttga ggttgtagat agaactgacg aagtcagtaa cctacatacg gcaaggcgac
     9961 gttgacgcgg tttgaagaga ttttcgaaga gtacaagacc ccaggttttt cttattcata
    10021 agttacgact gtaacagcac ccttgtcata ttcagcaata aagatattgg ctacattgtc
    10081 atgcccttgt ttgctgaggt tatcaagcaa ccactcttcg ctacgaccaa tcgattccaa
    10141 gacgtctact tgaatcacac cgtcagtcac aactggatac ttaggatttt catctcccat
    10201 ttgcacaacg atgagttgcc cattttgctc ttgcacagct cgtttgactt gcttcatctg
    10261 gaaaatccct tggctacgaa gtttgagggc tacatccgat gcagacaaac caactgaacg
    10321 acaggcttat gggtcaatat tcccattttt gataaggaga gttggcttac catcaatcaa
    10381 acgtttcaca aagtgaacat tgttgttgag ctatttgaga gtcaagatca gtttgattaa
    10441 aatttcgata taattaagtg tcatttgttc acatccacca gttcaattgc gtctgtctta
    10501 tacaattcga ctttctctaa caggtacttg tctggctcac ttccgtttag ggcacgataa
    10561 tagcgatctc ccaccttgat aagtgcgcca tctgtgtttg tggaagtatt aacatggact
    10621 tctgacttgt ctactcccaa atctttggaa acaacctcga tgaaatgaag tgaagtttga
    10681 aatttattgt tagaaacttg attgttttga taagtcgtga tgctgaccaa aagcatagct
    10741 aaataaggcc agagctgaaa tcatgaccaa ctcacgaaat ttggttcctt ttttatcatg
    10801 gtatgccttg aaagcaaaaa aaactgtcac agctaataga acaatcccaa agccaaccat
    10861 gataccattt tgctgaccga tttggctgag tacatagtca taagagtaga atttcatgta
    10921 ttttcactcc ctttcataaa atcattctta attataaacg aaagagagta atttttcaaa
    10981 ccatacgttg gggaaataga tctttttttg gtataataaa atctataatc tgaatgaaaa
    11041 aggtaacttt atgaaactta tctcatggaa tattgattcc ctaaacgctg ccctaactag
    11101 tgactcagct cgtgccaaat tgtcccaaga agtcctacaa accttggtcg ctgaaaatgc
    11161 tgatatcatt gctatccaag aaaccaagct ttctgccaaa ggacctacaa agaaacacgt
    11221 ggaaatttta gaagaactct tcccaggcta cgaaaacacg tggcgctctt cccaagagcc
    11281 tgcccgtaaa ggctatgctg gaaccatgtt cctttataag aaagaactta cacccactat
    11341 cagcttccca gaaatcggtg ccccttctac catggacttg gaaggccgta tcatcactct
    11401 agaatttgat gcatttttcg taacccaagt ttacactcca aacgctggtg acggtctcaa
    11461 acgcttggaa gaacgccaag tctgggatgt caaatatgcg gagtatttgg ctgaactaga
    11521 caaagaaaaa ccagtccttg cgaccggtga ctacaacgta gcccacaatg aaatcgacct
    11581 tgcaaatcct gctagcaacc gccgttcacc tggatttact gacgaggaac gtgctggatt
    11641 taccaaccta ttggcaactg gatttactga taccttccgc catgttcatg gcgatgttcc
    11701 tgaacgctac acttggtggg cacaacgcag caaaacttct aaaatcaaca atacaggctg
    11761 gagaatcgac tactggctca caagtaaccg tatcgctgac aaggtcacta aatctgatat
    11821 gattgactca ggtgctcgcc aagaccatac accgattgtc ttggaaattg acttgtaagg
    11881 attttctata tggactacaa tgcggtcatt cccgagtttc ttgtatcgaa tatcgaacag
    11941 tcccggtcct tctactgtgg tttactgggt tttaggattg aataccaacg ttcagaagaa
    12001 aactttctct ttctcttgaa gagtgtcaac taatgttaga ggagggaaca aaggatcaac
    12061 tagctgaact gacctacccc tttggtcgtg gagtcaatct ctcctttggc ataaaggatg
    12121 ttccaaaact ctatcaaaaa gtgatggagg caaactatcc tatttatcgt cccttgacca
    12181 aaagaaagtt tcgtgtcagt gatccctata tctatcctca taaatttgca gttttggatc
    12241 cagatggcta ttttttaaga tttagcgagt agaataataa aaattgggaa aagtctttaa
    12301 aagttagaaa aaggcatatt gtcaggtgtc taaaaacttg atagtatgcc ttttatgatg
    12361 gaaaaatctt ctaatactct tcgaaaatct cttcaagcca cgtcaacgtc gccttaccgt
    12421 aggtatataa tactgactct gtcaattcta tccacaacct caaaacagtg ttttgaggtt
    12481 gtggatagct tcctagtttg ctctttgatt ttcatttagt ataaatgtta gcttacaatg
    12541 gagtttttgt tcaccctctc ttctgtttgt tcgtttttta aaccaaaaca ctaacaaaat
    12601 agttgatttc taaagttatt tagtgtaaaa taaaaacatt ggctcaagcc tatttaaaat
    12661 tgaatatcgt tttacttgtt tatgtcgtga attggcacga cgtttctaca aggtgccgga
    12721 acacctaaca ataagtaagt cagcagtgag atatggccgt ttttgccatg cctatttggg
    12781 ggacttactt agagattaag taggtctttt ttgaatattt ttaatatttc ccttaattag
    12841 tgcggacggg aggtgaaatt atcctgtgaa taatttcagg aatccaggga atttcatccc
    12901 taatttttga gcccctagct ctttcatttc taggcttagg ctaaaatagt tccccgaact
    12961 attttactct caaaaatccc gtcatagaca ataacaagat tattgtctat gataccacta
    13021 caacgggaaa tatttgataa gactcgcttc gctcgtaata gttttatcaa atatatagca
    13081 ttagcaaaag ggatcactat agaaacattt aaacaacaag taaattaact tttagacttt
    13141 aggaggtctt atgaaattat tagaagagcg catcctcaag gatgggcata tcttgggtga
    13201 taacatcctc aaggtagatt cctttttaac ccaccaagtt gactttagct tgatgcgaga
    13261 gattggtaag gtttttgcgg aaaaatttgc tgctgccggc attaccaagg tcgtaaccat
    13321 tgaagcgtcg ggtattgccc cagccgtttt tacagctgaa gccttaaacg ttcccatgat
    13381 tttcgccaaa aaagctaaga acatcaccat gaacgaaggc atcttaactg ctcaagtcta
    13441 ctcctttacc aagcaggtga ccagcaccgt ttctatcgct ggaaaattcc tctcaccaga
    13501 ggacaaggtt ttgattatcg acgatttcct tgctaatggc caagctgcta aaggcttgat
    13561 tcaaatcatc gaacaggccg gtgccacagt ccaagctatc ggtatcgtga ttgagaaatc
    13621 cttccaagat ggccgtgatt tgcttgaaaa agcaggctac cctgtcctat cacttgctcg
    13681 tttggatcgt tttgaaaatg gtcaggtcgt atttaaggag gcagatctct aatgcaaact
    13741 caagaaaaac actcgcaagc agccgttctt ggcttgcagc acttactagc catgtactca
    13801 ggatctatcc tggttcccat catgattgcg acagcccttg gctattcagc tgagcagttg
    13861 acctacctga tttctacaga tatcttcatg tgtggggtgg caaccttcct ccaactccaa
    13921 ctcaacaaat actttgggat tggactccca gtcgttcttg gagttgcatt ccagtcggtc
    13981 gctcccttga ttatgattgg gcaaagccat ggtagtggcg ctatgtttgg tgcccttatc
    14041 gcatctggga tttacgtggt tcttgtttca ggcatcttct caaaagtggc caatctcttc
    14101 ccctctatcg taacaggatc tgttattacc acgattggtt taaccttgat ccctgtcgct
    14161 attggaaata tgggaaataa cgttccagag ccaactggtc aaagtctctt gctttcagct
    14221 attactgttc tgattatcct cttgatcaac atctttacca aaggatttat caagtctatc
    14281 tctattttga ttggtctggt tgttggaact gccattgctg ctactatggg cttggtggac
    14341 ttctctcctg ttgcggtagc tccacttgtc catgtcccaa ctccactcta ctttgggatg
    14401 ccaacctttg aaatctcatc tattgtcatg atgtgtatca tcgcaacggt gtctatggtt
    14461 gagtcaactg gtgtttatct agccttgtct gatatcacaa aagatccaat cgacagcacg
    14521 cgccttcgca acggttaccg cgcagaaggt ttggccgtac ttctcggagg aatctttaac
    14581 accttccctt acaccggatt ttcacaaaac gttggtttgg ttaaattgtc aggcatcaaa
    14641 aaacgcctgc caatctacta cgcagctggt ttcctggttc tccttggact gcttcctaag
    14701 tttggtgccc ttgcccaaat cattccaagc tccgtcctcg gcggtgccat gctggtgatg
    14761 tttggttttg tatctattca agggatgcaa atcctagccc gagttgactt tgctaacaat
    14821 gaacacaact tccttatcgc agctgtttca atcgctgcag gtgtcggtct caacaacagt
    14881 aatctctttg tcagcatgcc gacagccttc caaatgttct tctcaaacgg aatcgtcgta
    14941 gccagcctac tcgccattgt cctcaatgcc gtattaaatc ataaaaagaa ataagaaaaa
    15001 gaggtgcgag cctctttttt gtttatcaca aattgattat aaatacaatc aatcccaatt
    15061 cccatctaat tgaattggac ctatttcaaa ttctttaaaa tattatgttc caaatcgtta
    15121 atattatata agaatggtaa aatatcaaat gtttctcgta aattattctt agccttatac
    15181 caaccttgtc catcagtaat ccacataaac tcaacattag gaatagcttt aatttcttca
    15241 gcaatcattt tgtaagatct agccgtctca tttaattttg aaccacttcc tgaataaaaa
    15301 ttaacctcaa tcagataaag cacttgttca ttttttatga caaaatcaaa acgtttcaca
    15361 gtattcccat cattcgtaat agcagataaa tcgacagaaa aaatttcctc tatttcattt
    15421 tgttcaatct ctttaaataa attctctcct aaaatatacc cttcagcttc aagataactt
    15481 tgaacaatat tttccatcgc atctccagtc cgatttttgc gcccattagt atccatacca
    15541 acctcaacac ctgtaacgta gtcaactaaa tttgatacta aatgattttg caataaatca
    15601 aatatacctg atttttccaa aaacatagta tattcttcaa tactatagtt tcgtttacta
    15661 aaatcaaaat agaaatcttt tatcggatcc ttaacaataa tcgtatctct caaacgttta
    15721 gcaataagta gaggcacaac tttcaaaatt tctggataat tttgatataa gtctaaaaaa
    15781 tcctcttgta tatttttact accaataaga ctattcataa tatttagagc aacttttata
    15841 ctagatacat ttttataaac cttgggaaaa tctgtataat aagtccagtc agctactgtg
    15901 tcggtcatcg ttgacaacca ctcatcaaaa tttctagttt gtttcatttt ctgcctccaa
    15961 cctcttcctt gcaattttta aatattcttt ttcagcatcg atacctataa atcttctacc
    16021 taaccgcttc gcaacaacac ccgtagtgcc actaccaaca aatgggtcta gaatatagtc
    16081 accctcttta gtagaggcta aaataatgcg ttctaacaaa tactctggtt tttgagttgg
    16141 atgtttccca gcccattttt caactttctt tgttaaagaa cccgtccaga catctttcat
    16201 ttgttttcca tcattcaatt ctttcattaa atcataattg tagtaatgac gagctttttt
    16261 atcatttttt ctggcccata aaatggtttc agtagaatgg gtaaaataac gacaagataa
    16321 attgggggca gggtttgttt tctgccaagt aatattattc agaattttaa aaccttcttg
    16381 ttctaatgcc attccaactg agtatatgtt gtgcaaacta cctgaaatcc ataccgtccc
    16441 attaggcttc agaacttctt ttgctaggcg aatccattta cgattaaact catgtttttc
    16501 ttcgaatgaa gaaattttat cccaatctcc tttatcaaca gaaacaactt gtcccccaga
    16561 attagatatt ccaccattac ttaaaaaata aggtggatca gcaaaaatca tatccatact
    16621 ttctggtttc atttttgata agaacttgaa cgtatctgaa tgaacaagaa tcatcttatt
    16681 tttattgtag tatggttttg tcataagaac acctccatac ttatattcgt tatttttcat
    16741 aatttgtgac tataatttca gaaatttttc ctcgacttga agattttgct ccattagttc
    16801 gggtagcttc aacataatgt atattaaaat ccttatacaa ctcctctact aaagcactag
    16861 aagaatttga taacataaca taagctcctg tatcactcaa tctcttaaag gcatctctta
    16921 atcttacttg atctgcaaaa gagaatccct catgagtata agacgtaaat gcactcgtct
    16981 cagacaatgg aatatatgga gggtcaaaat acacaaaatc tcctgttcga acatctacaa
    17041 ttgccttttc aaaatctccc actttaattt ctagttgatt gttatttaga taaactgaaa
    17101 tagcagatat caattcctca tcaacaattt taggattctt ataacgtcca tatggaacat
    17161 taaattggtt cttagaattc acacgatata gaccattaaa gttcactctc aacatatata
    17221 gaatacgtgc agctctttgt acttcggaca tcatatctat tctttcatca cgatctgcag
    17281 aacgtaaatc taaataatat tcttttgaat tatattcctg atgaactttc aaaatttcaa
    17341 tcaattcttg aggattgtcc ttaatttgtt gatagcaatt tattagttca gcgttaaaat
    17401 cattaataac tgcatcttta ggagccaaat caaaaaataa agctccacct ccaacaaaag
    17461 gttcgaaata cctgttatag gttttaggca ttaattctct aataacaggc aataattgtc
    17521 ttttaccacc tgtccatttc gtgaacggtt gtaaagtaac tttctttatt tcttttatct
    17581 tcatgctttt aattatacca tagaaattaa aacacaactc ttgtattttc taccacatta
    17641 ctaaattttc tattttagaa ttaaatcata tcaatataaa aaaatgagta aggcaaatct
    17701 tataaattcc aaaattcacc tcactctatt aaattactct ttatatcctt acccgtcttt
    17761 cctcagacct ttggcctgtg acaaacatag taaaggttgc tttgcagaca tttctgccct
    17821 cttgattggt gatatccaca tccatcacac aggttgtacg accttgatgg acacattctc
    17881 ctttaatggt caatacatcg tcgagttttc ctgccttaag gtagttgata gaggattgga
    17941 gtgtcacccc atcaagtccc agcgagataa ccaccaaacc actgatttgg tcacatagtg
    18001 tgaatagata gccaccatgg gcattgccat agtagttgag cgacgagttc actactttgg
    18061 tcgtcaccac aacgtgacca tctctcattt tttcaatttc gtaattttca aaggcagata
    18121 tagcgtcaaa atgaaagtct ttcatcgttt cctcctgata tttcaaatga cactatgata
    18181 ctacttttta taggactgtg caaggagaaa gctcctagtc tagtaaaatt ccgacatgtt
    18241 ccacaaagcg cataaaggct gtctgccctt gttctgtctg cttgtagact cctgcatcct
    18301 caagtacacg cgcaaagata gcacccacag agtccttgac gattgcaagg gctttttctt
    18361 tatccgttag gtctggatgt tgggatttga gttggtctgc ccactcctga tgataatcgg
    18421 caactgtaac agcttctcct acaagatagc tagcgacttg ctctacttct tctttcagac
    18481 gtggtggcaa gattgccaag cccatgacct caatcaagcc gatattttcc ttcttgatat
    18541 gttggacatc cttgtgggga tgatagatgc catcaggatg atctgctgaa gtctgattgt
    18601 ctcgcaagac caagtccaac tcaaactgtc catcacgctt acgcgctatt ggtgtgatgg
    18661 tgtgatgcgg tgtcccgtct gtctctgcta aaatctgcac actagaatct gaatactgac
    18721 gccattcctg gaaaatctta tcagctaagt taatcaaatc ctctttggaa tccgaagtca
    18781 agcgtaggac agacattggc cacttgataa ttccagcctt gacctgctca aaaccagcaa
    18841 atcggaaggt cttttgcaag ggagccaatt ccataggaaa tacgtgacgg cctccctgat
    18901 aatgatcatg agttagaata gagcccccca caatcggcag gtcggcatta gatccagcaa
    18961 aatatcctgg aaactgctct acgatagcca acagacgttc aaaactctga cgactaatgg
    19021 ccatgggacg atgctggcca tctaaaaaga tacaatgctc attaaagtaa gcatagggcg
    19081 aatactggaa accccattcc tgaccaacca tttcaaaacg gataatccgg tggttgctgc
    19141 gagctgggtg gttgacccga ccatggtaac cctcattctc taaacaaagt tgacactgag
    19201 gataattact agcttgcacc aacttggcta ccgcaatctc tttcggatcc ttttcaggct
    19261 tagagagatt gatggtaatt tcaagttctc cataatcaga tggaacacga taaacgatat
    19321 ttttagcaat ggccttgagt ttgatgtagt catttttctg actgagttga taaaaatcct
    19381 ctatcgcttg ctcaggagag taggcatagg cttcccagaa gtcacgattg acctgactcg
    19441 gacaaggagt caccaagtcc atcaattcag taccaaggat ttcacgcgca gtctgactat
    19501 cctcaatcgt ctctaatcga acggcttcct caactagctg gtccttgagg tcaatcaatt
    19561 tatccagatt ggtctcaact tccaaaacac cttctcccac tcgtgccaaa acacgattgg
    19621 tcaggtagat tcgatccatt tcctcaaatg aactttcaga aatgacatgt gttacaaatt
    19681 tatctactaa ggtcactata gagcctcctt ttgactagtc aaggacgcga gtgccacctg
    19741 caacttcagc gatatagaag cttggagcgt atccaactac ttcctcgtag tgtttgccta
    19801 cagcttcctt aaaggcctca acagtatctt tttgaaccaa ggcaatggca cagccaccaa
    19861 aaccagcccc tgtcatacga gcaccgagaa ctccttcttg tgcccaagct gtgtgaacaa
    19921 gagtatccaa ttccaaacca gttacttcat aatcatgctc cagagaaacg tgtgacgcat
    19981 tcatcaaacg accaaatgtt tccaaatcac ctgcttgaag ggctgcttga gctttaaggg
    20041 tacgttggtt ttcaaacaca gcatggcgag cacgtttcaa acgattttca tctttaatca
    20101 gatagctata ttggtcaacg gcccactcgt ccaattcacc cagggtctga atatccaagg
    20161 caacttgcaa ttcttccact gctttttcac actcagcacg acgttcattg tatttagagt
    20221 ccgccaattc acggcgtttg ttggtgttca tgataacaac gacattgtcc ttcaaatcaa
    20281 gtggcaccaa gtcgtattct aaagtattgg tatctaagta aatagcacgt tggtcagccc
    20341 ccataccaat agcaaattgg tccatgatac cagagttgac tccgataaag ttattttctg
    20401 tttgttttcc gattttaacc aaatcgagac gctctagttt taaatcaaag agatgctctg
    20461 ccacgactcc tgtcaagagc tccaaggatg ctgaagaaga caaaccagca ccatttggga
    20521 tattcccata aacataaaaa tcaaaacctt tgtcaatcac gtgcccagct tcttgcaaga
    20581 aatgaaggac accttttgga taattggtcc agttgtgctc tttttcaaac ttgaggtcag
    20641 cgagaggcac ttcgataatg cccttgtcct caaagttagc tgagtagaaa cgcaagactt
    20701 ggtcgtcacg cttacgagct gcaccgtaag ttcccaagga aatagcagca ggaaaaacgt
    20761 gcccaccgtt gtagtctgtg tgttcaccaa tcaaattaat gcggcctggt gaaaagaagg
    20821 tttggtctgc ttcttgacca aaaacagcaa gaaagtcttt gcgaagggct tcagtagtaa
    20881 gatgttgtgc catatgaatt ctcctttgac tgtccgttaa gccaccttaa cgtataatcg
    20941 ttttctttct attgtatcca aggaattttc caagatcaat cctttttact aaaattttag
    21001 taaaatatca gtaaaaagaa gaaaaacatg atatactaac ctaatcaagg aggatttatg
    21061 gctaccttaa aagacattgc acagctagcc tctgtctcta tcgcgaccgt atcccgcgtc
    21121 ctcaatcgcg accagagcct atctgttaca gaagaaacca gacaccgtat tttaaccgtt
    21181 gctgaagagc tgggctacac caagcacctc aagacaggcg agtcccacaa acccaagcaa
    21241 aagattgcca ttatccaatg ggtcagcgaa caaggggagc tggacgacct ctactactac
    21301 cagattcgcc taggaataga aaaaagagcc caagagttgg actatgatat cttgcgctat
    21361 tttaatgacc atccttttac cttaagcgag gaagtgattg ggattctctg cattggaaaa
    21421 tttagccgag ctcagatttc tgcctttgaa gaataccaaa aacccctggt ctttctagac
    21481 agtgatacac tttctctggg gcatacttgt attattacgg atttttacac tgccatgaaa
    21541 caggttgtcg attatttcct cagccaagga atggaccgta tcgggattct aacaggcctt
    21601 gaagaaacaa ctgaccaaga agaaatcatt caggataagc ggctggaaaa tttcagaaac
    21661 tacagtcaag caaaaggaat ctatcatgat gaactggtct ttcaaggaaa ctttactgcc
    21721 cagtctggct atgacttgat gaaggaagcc attcagaact tgggagacca actcccacca
    21781 gcatttttcg cagccagcga tagtttagct atcggtgccc ttcgtgccct ccaagaagct
    21841 ggaatcagcc taccagaccg tgtcagcctc atttccttta acgacaccag cctgaccaag
    21901 caggtttatc ctcccctctc cagcatcaca gtttatactg aagaaatggg gcgagcaggt
    21961 atggatattc ttaacaagga agtcctccac gatcgcaaaa ttcctagcct gaccatgctg
    22021 ggaaccagac tgacattaag agaaagtacc ctaaatcaag aataggataa cataaaaaac
    22081 gaatagagtt ctaaaactcc tattcgtttt ttattcgatt acaatcatag acttaatggt
    22141 cttacgttca tccatatctt tgtaggcttg gtcgatatct tccagtttat aacttgaagt
    22201 aaagacgcga cctggattga tatcaccatc aaggacggct tttagtaaaa attgcttatc
    22261 gtatgttgta gcagaagctg ccccacctgc tacagagata ttttgcataa atgtcgaacc
    22321 aagagcacga ttattatagt gtgggactcc tacaaagccc atacgccctc cattatgaag
    22381 aacacctagc gcctgttcta tagcagcctc cgtaccaaca cattcaagtg ctgcgtctgc
    22441 tcctccaccg aggatttcac gcaccttggt aattccttct tgaccacgtt ctgcaacaac
    22501 agctgtcgca cctgactcca tagccatctt ttgacggtct tcatgacggc tcataaggat
    22561 aatttgtgat gctccacgca tcttagccgc gatgacagca cattgaccaa cagccccatc
    22621 accgataaca acaaccttgt cccctttttg aacatttgca acacgcgccg catgatagcc
    22681 tgtcggcatg acatctgcaa gagtcaaaag ggactggagc atcccttctg tatagtcaga
    22741 aggttgacca gggattttaa ccagcgccca gtttgcatag tggaagcgaa tatattctgc
    22801 ctgaaaatca ccccccaaat tattgccaat atgattgtcg caagaaccgt caaatccagc
    22861 aagacaggca tcacactcac cacatccatg tgtaaaaggg acaatcacaa aatcacctgg
    22921 tttcaccgtc gtaatggctt ccacagcttc ttcaacaatc ccaatcgctt cgtgtccact
    22981 atttttgtgt ccagctttcg tttctggatt acggtacctc cataaatctg aaccacaaac
    23041 gcacgcacga accacacgaa taatcacatc atccgcttct attatttgcg gacgttcaat
    23101 gctagcaagt ccaacctgac ctgcctttgt atatactgct gatttcattt aaaattttcc
    23161 ttccttataa agtttaattt tgagatttaa acgatttaaa gctgtctgta gctgagacaa
    23221 gcgctcctct aatttttgct tttcctcttc taaaatacca agcctctcct ctctcgtttc
    23281 atctcccttt tggtagagcg acatatagtc aactaaacta tctacagaga cacccgccga
    23341 acgaaaacac ttaataaatt ccagcgcttc gatatcctga tcttgaaaat cacgaatccc
    23401 agtagcagta cgagtaatcg gtggcacaag accaacccgt tcataatacc gaatcgtatc
    23461 cgctgaaatt cccaacaaat cactggcaga tttaatattc acacgctaac ctcctctcat
    23521 ttcattcact gaattcacgc tattctaact cacttatctt attatataac tttgagttga
    23581 ctccaagtca agcattttgt atctaatcga aaaattttta tcattaacaa tcatatatct
    23641 ggagtttata caatgctctt ctcttaccaa tttttgaaat atttaaataa taaagaaatt
    23701 actctattcc aaataagata gtacccaagt atttttcact tttttctaat gttgatgctc
    23761 ataactccgt tccaagtcac acacctttcg cttatgggtt tggtgagttt ctaggtcagc
    23821 atcaatttca atggtaatat tttgaaaacc acaatctttt aggaaaattc gaatagactc
    23881 tttacaagtt tccatatgtt ccatttcttt tagacaaaca tggacaatgg catttttttc
    23941 caaagcatcc atagtccaga gattaagctg attaaggctg gccacattgt ccaatcgctc
    24001 caggccactc tttacttgct tgatatcaag accttctggc acagcatcca agaaaatctt
    24061 gagtgtagac caaaaacgtg gaagggcttt tgaaagaata aagaaagaaa tgacaaggga
    24121 caaaagagga tctaggatat accagtccgt aaatcgaaga acaatcgcca tcaggataac
    24181 agctacccac cctagcgtat cttccagaaa atgcagactc agaatagact cattctttgt
    24241 ctttccctta ccaaccacca gactcgctaa cagattgata gtaatcgcaa taattcctaa
    24301 ccagagaatc ccctcatcat tgactggttg cggatgcaaa atcttcgtga cattttccaa
    24361 aatgactaga acagagcccg ttacgagaat cacagctgtt accaaggctc ctagcaggct
    24421 aaaccgctta tagcccaagg tgtactgatt gtcttcttca cgattggaga ttgtttctag
    24481 aaaagctgat attccaattg caatcgcatc tcccaagtca tgcacagagt cagcaagaac
    24541 agcgctagaa ccaaatactc cacctgcaat aaactcaaca atggcataag tcaaatttaa
    24601 gaaaaaagcc acccaaacag catattttgc cttcatattt ctcattcctt tgttataata
    24661 gatttatgaa caccttgttc attatcatta tccactaaaa ctcaaagaaa ggatagaagc
    24721 aaaacgtcag ctttattcag ttctgaacaa tttgccttaa gtgtccatat gactaacatt
    24781 gaccgccgta tcagcaaaac caaaaaagcc atctatcaag cttttataca acttttgaat
    24841 gctaagggct acgaggccac tactgttcag gatatcattg atctcgcaga tgtgggacga
    24901 tccacctttt actgtcacta tgagagtaag gagcttcttc tggaccagct ctgccgctac
    24961 ctcttccatc atctttttga aagagagcaa gccatttcaa ccgaggacta cctcgcccac
    25021 ctctttctcc attttcataa aaaccaagac catatcacca gtctgctatt ttccaaaaat
    25081 gactacttcc tccgtcaact ccataaagag ctagaacacc atgtctattc cgtgctagct
    25141 gataatttaa aagaagccca ccctaatctg cctacttctt acctccaaca cttggtcatg
    25201 tccaacttta tcgagacatt gacctggtgg ctcaaaaaag gtcaagattt cacagaccag
    25261 gaagttgtcc aattttatct agaccttctc attcctaaaa attgaatata gagtaaagct
    25321 tcagttgtct tatttctagg ttactgagtt ttttatcttt tcaacaacaa aagaggaccc
    25381 gccgatcctc tttttcatac tataaatcct tgattatcaa ctatatctgt tttaatcgaa
    25441 atctcaaaac agcactttca aacatctttt cctagttaag taaatcagta ttctgcttag
    25501 ctgccttgct ccattgatac caaccaacta gactgttaat gagataaatt agatatttcc
    25561 cttgaatttg caggctttct ccccaccaga gatagattga aaagacattg gtagccgccc
    25621 agaatatcca ctgttcacgg taaacagctg tcatgaggat ttgccctacc ccattggttg
    25681 catctgtgat tgaatcacga tagggacgat tggcaccaat agactgataa atgaagccaa
    25741 aggccaacca ccaaagcaca ctaatggaaa gatactttgt ccagcccttg ccgtccagtt
    25801 tacgcgcgac aaactcctgc ttttccttct taaactgtgc ctgataaatc caaactagaa
    25861 gtccaattgg ctgcatgact gtgaagtaaa gtgtcgtcag cacctcacca taaaagcctt
    25921 tctgtagggc caaaataagg taaataacag agttaatcaa gccaaaaaga taattacttg
    25981 ctcgaccttc cgatacaaag attacacaga taatccctgt caagctacaa atcatcccaa
    26041 tccagtcaac aatacgatgt tcgtaaacca actccagcca gagaggaaaa cttcctaaaa
    26101 ccagcaaata aatccactgg gcaaaactac gatgggcaaa gaggtcatcc cagatagcct
    26161 tcatagttcc tgaaaatcct aaatcagcca tagccgcaac catacgacgg taaccacctg
    26221 acatttcacc tagggttgtt ttgatatttt caattttctt ttgcaaataa gtatgcatca
    26281 tttctccttt tgtttttaaa gagccgtgtc tggatagact ttcggacgca acgctctatt
    26341 agataatgaa ctgcctatac acaagatttc taaccttagt cgacatgagc tgaaacctct
    26401 tatttgttaa gtagttcaca aaatattata cacctatttt atgaatagtc aactgtcttt
    26461 acagtaaaat tttagaaaat catgaaaatt ttctctttct ttccatttta agtgacattc
    26521 agtcattctc acatcaaaaa agcccagacg aaattgtctg agcattcttt tatctagtcg
    26581 tttaaggaag ttgagttcag tatgtttaaa gtctctgtcc catcatttct tcaacaaacc
    26641 ttgttcttgg agaaactcct tggctacttg ctttgctgac ttgccttcaa caccgacttg
    26701 gtagttgagc tggctcatct ggctttctgt aatcttacca gccaatgtat taagaactct
    26761 ttccaactct gggtgtttct tgagaagagc ttctttcatg agtggagccc cttgataagg
    26821 tgggaagagt tgcttgtcat cttccaagac ctgtaaatca taacgctcca attccgcatc
    26881 agtcgaatag gcatccgtga tttgaatatc ccctgactga atagcctgat agcgaagggc
    26941 tggctccatg gtcgctacat tgagattgag accatacatt gattgcaagc ccttatttcc
    27001 atcttcacgg tcgttaaact cgagtgtaaa acctgccttc aactgccctt ccactttttt
    27061 caagtctgaa atggtcttca agccatattc ttgagcaatc tttttcggaa cagctacagc
    27121 ataggtgttt tgataagaca tgggtttgag ataggctaga tgatcctgct tagcaatgcc
    27181 atcacgcgcc acctgataaa cctgttctgg ttcatgactc accttgggtg atggttgaag
    27241 caaactttca gtcaccgtac cagtaaattc aggatagatg tcaatatcgc cttttttcag
    27301 agcttcataa aggaagcttg tcttcccaaa attcggttta acagtcgcag tcatgctggt
    27361 attttcttca atcagcaact tatacatatt ggccaaaatt tctggttctg gacctatttt
    27421 cccagcaata accaagtttt ccttctcttt ttgaaccaaa agagctggac tataagacag
    27481 acccagtaat aaagccacca aggcaaaacc tgagaaaatc gtccgtaatt ttgctttttc
    27541 catcactttt agtaggaagt taaaggcaat ggctagcact gcagaagaaa gtgccccaat
    27601 caaaatcaaa ctggcattat tacggtcaat tcccaaaaga ataaaggaac ctagtccccc
    27661 tgcaccaatc aaggccgcca aggttgccgt accgataatc aaaacagctg ccgtccgaat
    27721 cccagacatg ataacaggca tggcgagtgg aatttcaaat ttcttgagac gttcccatct
    27781 ggtcatccca aaggcaatcc cagcctcttg caggttcgga tcaattccct tcagcccagt
    27841 gatagtattt tgcaaaatag ggaaaatcgc ataaatcact agagctgtca aagccggcaa
    27901 ggtcccaatt cccatcaaag ggataaagag ccccaacaag gccagagacg ggatggtctg
    27961 gaaaatacct gcaatctgca agacccagtc ggccagcttc tcatgatagc gaagaaaaac
    28021 agccaaggga atcgcaagca aaatagctag taacaaggtc aaaagcgaca actgcaaatg
    28081 ttgagataga gctgtcaacc aatcactaaa acgatcctga aaagttgcaa ttaaattagt
    28141 catgaacact acctccaaac aagtctgcta caaagtctgt tgcaggcgct tttaaaattg
    28201 tctcgggatt cgctacctgg cgaatttctc catcctgcaa gacagcaata cggtccgcca
    28261 acttcaaggc ttcatccgta tcatgggtta caaaaatcgt tgtcatccca aactctttat
    28321 gcaattcttt tgtcagaacc tgcaactgtt ttctcgaaat agcatccaag gccgaaaagg
    28381 gttcatccat gaggaaaatc ttgggctgac caatcatagc tcggacaata ccgacccgtt
    28441 gctgttctcc accagataat tcactaggta agcgatgccc atactcggct actggtaaac
    28501 caaccttagc caaaagctct tctgttttct tcgtaatttc ttccttgctc caccccttca
    28561 tttcaggaat gagagcaata ttttccgcaa ctgttagatt tggaaaaaga gcaatagcct
    28621 gtaaaacata accagtagaa agacgaagtt cacgctcatc atagtctttg atgcgcttcc
    28681 catccatata aatatttcca tcagttggtt ccaaaagacg gttaatcatc ttgagcatgg
    28741 tcgtcttacc tgacccagaa ggccctacta aaaccataaa ttccccatcc tcaatctgta
    28801 agttgacatc tctcaagaca tccttttctg tgtagcgcag tgctacattt ttgtattcaa
    28861 tcattctttg tcctcaattt aaaacttccc tcgattggtc aagtcttcta ccttaggcat
    28921 aacttcctta ttatcccaat gctccacaat tttcccgttc tctaaacgga agatatcgta
    28981 ctgggcataa gcaacgccat caatctgagt ctgaccatag ctaaccacat agtttccttg
    29041 tcctaagagt tggaaaacaa agtcaaaagt gacactatat tcagccacat agtttttata
    29101 agcagcactt ccttgtccaa tatcatgatt atgctgaatc aaatcgtctg ccacataatc
    29161 actccactgc tctagctccc cattttggaa aatttctgtc aagaaacggc gaaccagctt
    29221 tttattttct gctttcttgt ccaaatcctt gatttcaaaa tctccaaaaa tttgatctag
    29281 ttggtcattt tcaggtgttc gatagtagtc aacgacatcc caatgctcaa caatacgacc
    29341 attctcatcc gcacggaaag tatccgtcgt cacccattga gcttctccac cattcagata
    29401 ttgatgaaca tgaacaaaga ccagattgcc atcctcaatg gtgcggacaa tcttaatctg
    29461 acgctctgga tgacgctcaa agaaatctgc aaagaaggct gcaaatcctt ctttcccgtc
    29521 aggaacacct gtcgaatgtt ggatataggt atcccctaca gactgggctt gagcctcagc
    29581 aactcgcccg tcttgaatgg catggatgta taggttgtga gcatttttca cttgttgtga
    29641 catattctaa acctcatttc ccttctcttt cagattcgcc aaaattcttt cttgaaaacc
    29701 ttcaaattgg tgaatttctt cctctgaaaa tcctttgtaa aagatagtat ccaatttctg
    29761 actgacacga tgccccactt ctttctggaa cttgcctaac tccgttaaaa ctaaatactt
    29821 cttacgcttg tcttttccac acggactaac aattacaagc ttttgttcct ctagcttttt
    29881 tatcatagtc gtcagcgtat tattcgcaag cccagtcgca agcgcgatat ctgtcgcagt
    29941 tgcgcagcca gtttcactat tccataaaac cgctaaaatc ttgccctgtt cacccctata
    30001 aagagcctca ggatcttgac tcagtaactt ttgaaaaatc cgcccattca acaaacgaat
    30061 atgatgggct agcaaatgac tatctttcat aacacctcca atttatttcg atatcgaaat
    30121 gaataaaata attgtaacac tcatcgttct aactgtcaac tatttcgatt tggaaataat
    30181 ttttgataat tatccacacc accatactcc ggctcaacta acttttaacg agagtttcta
    30241 aactccttcg tcctccagtc tacaaaagcc ttccattcgt actatcctat attttatgag
    30301 gggacacatt tttcctatca gaccatttat tttaaagata gaagtaaatc ataattgctt
    30361 ccatctgttc ttttatagta tattgaagtt agactagagc actgtatctt ctaaaacatt
    30421 gatagaaagc gatttgaatt tcccaatcaa tttgttcgta tttatagcat tttgaaacta
    30481 gaataggaca ccatgactgc taaaagattt ctataaattc atttgatttt cctaatcaat
    30541 ttgttcatat cttatttcat tccgctataa tttcacctta ccctatcttt ttcgtagcac
    30601 ccttcaaaca gcctatcccc taccgtttga cgattcctca cttcgctcca cttccattac
    30661 agaagtttct tcactactat gggctcggct gacttctcat gattccttgt tactactatt
    30721 tgaacgctca cgagatagat cttacaaaaa atgctttgat ccacaatgga atcaaagcat
    30781 tttaaagagt tcctcataca taagcgcaga agtcgcagtt cctctgtact tggcttcttc
    30841 tcttttgata aagcgagcca agttgagcaa ctcaggtgct ggatgtttgg gatttaggag
    30901 caattcacga ttgaccaggc ctgagagacg aactgcctgc aattgctcat ttgtagtagg
    30961 cagtttttta gcagtctcta ggagagcagc aactaaatct tcactcaaat catgtcgagc
    31021 atgattgtaa agatctttta taaggctttc taggtttggt tctgccatcc ctaccacctc
    31081 ccttatggtt taataatgtt taatcaaatc aaccgttgaa cgatccaatt tcttcaccaa
    31141 ggcttgtaag aaagcttgcg cttctaggaa gtcatccatt gcatagaggg tttggtgaga
    31201 atggatataa cgagcgcaga caccgatagt tgttgatggg acaccaccat ttttcagatg
    31261 agctgcacct gcatctgttc cgcctttacc acagtagtat tggtacttga taccagcttc
    31321 ttcagccgtt gtcaaaagaa aatccttcat ccctgggaga agcaagtgac ctggatcata
    31381 gaaacgaatc aaggttccat ctccaatctt gccttgacca ccgtagacat cacctgctgg
    31441 tgagcaatca actgcgagga agacttctgg gtcaaacttg gttgtagagg tatgagcgcc
    31501 acgcagacca acttcttctt ggacgttaga acccagatag agttcattgc cgagtttttg
    31561 acctgataaa gcttcagcta gctcgcttac catgaggaca ccgtagcggt tatcccaagc
    31621 ttttgagatg atattttttt cattggctgt caaaattgca gaactatctg gtacgatggt
    31681 atcaccagga cggatgccaa aactttctgc ctcagccttg tccgcaaaac caccatcaaa
    31741 aacgatatcg gcaatggctg gcatggttgg tccccccttt ccacgagtca aatgcggagg
    31801 aacagaacct gaaatcacag gaatttcatg accatcacga gtcaagagtt tgaaacgttg
    31861 gctgctaacc accatggggt tccagccacc gatttctacg acacggaagg taccatctgg
    31921 cttgatttcg ctgaccataa aaccaacttc gtccatatga gaagcgacca agacgcgcgg
    31981 tgcatccaca gcttctgaat gtttgatacc aaaaatacca cccaagccat ctgtcaccac
    32041 ttcatccaca tgcggtgtca acttttcacg aagataagca cggacaggcg cttcatgacc
    32101 tgagactgca gcaagttctg ttacttcttt aatttttgaa aataatgttg tcatttcagt
    32161 tccttctttc tttcatccat tttaccactt tttataggag aaggatagtg ggaaggtgga
    32221 tttctaagtt agtatcttag tcctgctcta tcttagaaaa ggatagtatt ctcttgcatg
    32281 tagtgcaaaa tctagtaaac attccaaaat taactcgaat atttatttcc aaacaaaaaa
    32341 acaatacacc atcaaagttg tttgtatttt tcatgaaatt tacagaaaat agttgacttc
    32401 cctttcttct ttctttaaat atatagttgg ttgagtttgg aatagtacgc tgtagctgct
    32461 gaaacatttc tagaaattaa tttgactttc ctaatagagt tgttcatatc ttatttcaat
    32521 ttactatagt acaaaactag aaaaggaaaa aatcatgacc aaaacaattc ttgttacagg
    32581 tgggactagc tacattggct cccataccgt taaagctctt ttaaatgctg gctataaggt
    32641 gcatgtcctc gataatctct ccacaggaaa tcgagcggct gtggatagtc gtgctagctt
    32701 taaagaactg gatgtttatg atgctagcgc cttaaaggct tacttagaag aaaatcagat
    32761 tgatgctgtc ctccattgtg caggtgaaat tgttgtgagc gaaagtattg aaaatccaag
    32821 taaatacttc actgccaacg ttgctggtat gaaccaagtt ctcaaagtct tatctgaagt
    32881 tggcattcaa aaaatcatgt tctcttcgac tgcttctctc tatggaaata actgtattga
    32941 caagccagtg actgaagata ccctgctcga ccctgtcaac ccttatgcag agacaaaact
    33001 gatgggcgaa cgaatgattt actggatggc caatcgctac gactggaaat atgttatttt
    33061 ccgttacttt aatgttgctg gggctgaaat ggatgcttca aacggtctgc gtgtgaaaaa
    33121 tccaactcac atcattccaa atatcaacaa gaccgcattg ggacaaaatg atagcttaaa
    33181 aatatttgga gatgactacg atacacgtga cggttcatgt attcgagatt acatttatgt
    33241 cttggacctt gcataggctc atgttaaagg aatgaactac ctatttcaag aagacagttc
    33301 ttctcaaatc tttaacttag gaactaaaaa aggctatact atcaaagaaa tctttaaaac
    33361 tgctgaagaa ttactaaatt aaaaaatccc acacgagatt gttgctcgac gtgctagtga
    33421 cccagccagt gtcctagcag atgcttcaaa agctaaacaa tatcttgatt ggacggctag
    33481 ctactccctc gaagatatta ttttatcaga ttaaggtaaa aacattttag aataggataa
    33541 caaaggagaa agtcttgttg ctctctcctt gttgtattta ttaaattgtc agaaatttta
    33601 ttgacagatt agaaaaataa tgttacattt atatccgcag atatctttcg ataccaaatc
    33661 tacatgaaag gacggggtat gaaactttct cattatttaa ttggcttact tctactccta
    33721 gtctttctct ctattagcat tgggaccagt gatttttcat ggggaaagct atttgatttc
    33781 gaccagcaga catggctcct ctttcaagag tcccgtctcc caagaactat cagtattctc
    33841 ctgactgcct ctagtatgag tatggcaggc cttctcatgc agactattac ccaaaatcag
    33901 tttgctgcac cgagtacagt tggaacgact gaagccgcca aactgggaat ggtgctgagc
    33961 ctttttgtct ttccatcggc tagtctgacc caaaagatgc tcttcgcttt tgtttcatcc
    34021 atcgtattca ccctcttctt cctagccttt atgaccattt ttactgtaaa ggaaaggtgg
    34081 atgttgcctc tgattgggat catctatagc gggattatcg gctcagtcac agaagttatc
    34141 gcctatcgtt tcaatctggt tcagagtatg actgcctgga cccagggctc cttctccatg
    34201 attcagaccc atcagtatga gtggctcttc ttaggcctca tcatcctgat aaccgtttgg
    34261 aaattatccc aaaccttcac catcatgaat ctggggaaag aaatcagcga gagtttgggg
    34321 atttcctact ccctacttga aaaactggcc ctctttctgg tggcgctaac gacaagcgtc
    34381 accatgatta ccgtgggtgg cctaccattt ctcggagtta tcgttcccaa tcttgttcgc
    34441 aagcgctatg gagataatct aagtcaaacc aaactcatgg tcgcactggt tggtgccaat
    34501 ctagttctgg cttgcgatat cctatcccga gttctgatta ggccctatga gttgtctgtc
    34561 agtctcttgc taggaatcat cggtagtctc ggctttatcc tacttctctg gagaggggga
    34621 cgaaaagatg cagactaaaa gcaaacatac caagctcttc tggattctca ttattcttgc
    34681 catcggagct tgtcttctct acttttggcc catcactcac ttgtcagcct ttgcttggaa
    34741 gttgcgttcc caaaagatca tcgtttatct cttggtagcc atcgcgactg ggatttcgac
    34801 cattagtttt caaaccctga cggaaaatcg cttcctgacg cctagtattt tgggaattga
    34861 atccttctac gtcctactac aaaccctact actggttttt gaaagcaagt ttcttcaact
    34921 tggcaaatcc cctatcttag aattcctagt cttacttctt gtccagtccc tcttctttct
    34981 caccttacaa ggttacttga agacactgat gaagcaagac ctggtcttca tcctgctgat
    35041 ctgtctagcg ctcagaagtc tctttcgaaa tatcagcacc ttccttcaag tcctaatgga
    35101 tccaaacgaa tacgataaac tgcaaaatag tctttttgcc tcctttcaac atctcaacac
    35161 ttccatccta gccatcggtt ctctgatcat cctcgctttg acaatctttt tctttcgaaa
    35221 agcagtcgtt ctagatgtct tgcacctgca aagagaaacg gctcagatat tgggactcga
    35281 tgttgaaaaa gaacagaaag agctcctctg gggaatcgtg cttttgacct caacggccac
    35341 tgccttggta ggacctatgg ccttcttcgg ctttatgctg gccaacctca cctacctgat
    35401 tgtcaaagac tatcagcaca agttactctt tatagtggcc attctggttg gatttattag
    35461 cttaaccttg gggcaagcct tgattgaacg agtctttgca ctggaaattc gtatcagtat
    35521 gatcattgag agtgtgggtg gcttcttatt ctttatctta ctatatagga ggtctcgtca
    35581 gtgaaactgg aaaacattga caaatccatt caaaaacagg atattttgca aggcatttcg
    35641 cttgaagtca gtcctcaaaa actgacagcc tttattggtc caaatggtgc tggaaaatcg
    35701 actctcctct ccatcatgag cagactaacc aagaaagatc agggagttct cagtatcaaa
    35761 ggacgtgaaa tcgagagctg gaattcgcaa gaactggccc aagaactaac catcctaaaa
    35821 cagaaaatca attaccaagc caaattgact gttgaagaac tggtcagttt tggacgtttt
    35881 ccctacagcc gaggtcgact tagatcagaa gactgggaaa aaatccgaga aactctgaac
    35941 tatttggaac tgaccaactt aaaagaccgc tacatcaata gcctgtcagg ggggcaactc
    36001 cagcgcgtct ttatcgctat ggtactggcc caggatacgg actttatctt gctggacgaa
    36061 ccactcaaca atctcgatat caagcaaagc gtcagcatga tgcagattct tcgacgactg
    36121 gtggaggaac tcggcaagac cattatcatc gtcctccacg atatcaacat ggccagtcag
    36181 tatgcagatg aaattgtcgc cttcaaggac ggccaggtct ttagcaaggg aagcaccgat
    36241 caaatcatgc aggctgacct gctcagtcaa ctttatgaga ttcccatcac gctagctgat
    36301 atcaatgaca aaaagatctg tatctatagc tagtaacata aaagctcaag ttagagaacc
    36361 ttcagtctct tagtcaataa gattaagaga ctccctaaat cgttatcaca ttttaaaaag
    36421 gagaaattat gaaaacatcc cttaaacttt atttcactgc cctagtggcc agcttcttgc
    36481 tcctacttgg tgcatgtagt acaaactcaa gcactagtca gacagagacc agtagctctg
    36541 ctccaacaga ggtaaccatt aaaagttcac tggacgaggt caaactttcc aaagttcctg
    36601 aaaagattgt gacctttgac ctcggcgctg cggatactat tcgcgcttta ggatttgaaa
    36661 aaaatatcgt cggaatgcct acaaaaactg ttccgactta tctaaaagac ctagtgggaa
    36721 ctgtcaaaaa tgttggttct atgaaagaac ctgatttaga agctatcgcc gcccttgagc
    36781 ctgatttgat tatcgcttca ccacgtacac aaaaattcgt agacaaattc aaagaaatcg
    36841 ccccaaccgt tctcttccaa gcaagcaagg acgactactg gacttctacc aaggctaata
    36901 tcgaatcctt agcaagtgcc ttcggcgaaa ctggtacaca gaaagccaag gaagaattgg
    36961 ccaagctaga caagagcatc caagaagtcg ctactaaaaa tgaaagctct gacaaaaaag
    37021 cccttgcgat cctccttaat gaaggaaaaa tggcagcctt tggtgccaaa tctcgtttct
    37081 ctttcttgta ccaaaccttg aaattcaaac caactgatac aaaatttgaa gactcacgcc
    37141 acggacaaga agtcagcttt gaaagtgtca aagaaatcaa ccctgccatc ctctttgtca
    37201 tcaaccgtac ccttgccatc ggtggggaca actctagcaa cgacggtgtc ctagaaaatg
    37261 cccttatcgc tgaaacacct gctgctaaaa atggtaagat tatccaacta acaccagacc
    37321 tctggtatct aagcggaggc ggacttgaat caacaaaact catgattgaa gacatacaaa
    37381 aagctttgaa ataagccact tcaaactcaa tttaatactc aatgaaaatc aaagagcaaa
    37441 ctaggaaact agccgcaggt tgctcaaaac actgttttga ggttgcagat gaaagctgac
    37501 gcggtttgaa gggattttcg aagagtataa aattttgaca ttctaaaacg catcctatca
    37561 agttcactca aacctgatag gatgcgtttt tatcattttg aaatctattt accccacctc
    37621 attccccttc ttgatttcgt ttaagggaaa agtggtctgg aacggggtcc ttacctgttt
    37681 tcgaccaggg atgacaacgt aaaatccgag ccaagcccat caataccccc ttaaaaccat
    37741 gtttttcaat agcctgaatc atgtagttgg aacaagtcag ctcaaagcga caagagggtg
    37801 gaaagactgg tgagataaaa cgttggtaaa agcgcacagg cgctattaaa attcgtttca
    37861 ttatttctta gttacagcca tggtgtgtag ttggctgatt tcttttttat taagacgacg
    37921 ggattctcct ggacggagtc ctgtcaagtc taggtgtccg aaacgagtcc gagacaactt
    37981 atctacttgg agaccaacag cttcaaacat ctttttaacc tgatggttac gcccttcatg
    38041 gatggtcaac tgcaccacag agcgattttt gactgggtcc actttgagaa tttcataaac
    38101 agctggcttg gttttcttac catcaatctc aagaccacgg gtcaaggggc ggagattgtc
    38161 cttattggcc acacccttaa cacgcgcgac ataaaccttg tcaatctcat tacgagggtg
    38221 aatcatctcg tctgtaaagt ccccatcatt ggtcaaaatc aagacacctg atgtatccca
    38281 gtccaaacga cccacagggt aaatacgctc tttgacattg ggcaagaggt cgacaaccgt
    38341 cttgcgaccc ttatcatctg tcacactgga aatcacaccg cgtggtttgt taagcagata
    38401 gtagaccttt tcttcgttgt agataggttg accttcaact tcgaccttgt cgcctgactt
    38461 gatagtggtt gctagttcac gcaccacttg gccgttaacc gtcaccaagc cttgcttaat
    38521 cagctcttct gcttttctcc tactggccac acctgcgtgg gcaatatact tattgattct
    38581 catcttcttc tatcctttca ccaaataatt ggctttcttg ggcttgaatc tcaagctcat
    38641 caatcactgg taattcttct aaatggttta tccccatgta atctaggaaa taatccgtag
    38701 tcacatagag gttggggcgc cccaatactt cctttttccc gtcttccttt atcaggtcaa
    38761 aagcctgcaa ctttgccaag gctccactcg agttaactcc acggatggca tcaatttcta
    38821 tccgcgtaat cggctgtttg taggcaataa tggacaaggt ctcaagggca gcccgagaca
    38881 agctctggtt gataggcgcc ttagagtatt ccttcaaaat ctctgcaaat tgagacttgg
    38941 tcaccaatct ataagcacca cttgtctcaa tcaaagccaa actggaatct gggtcctttt
    39001 catacttctg ggctaatttt cctaaactct gctggatgcc tgtcggtggc agagagagga
    39061 gttcagctaa ctggcggacc cgaatcccat cttcacccgc tacaaacaag agcgcttcta
    39121 tttttgctaa agtactcatc tttcctctct atcaagtcta gctttgaggc acttgacttt
    39181 cttccttctt ttccatgaga tagatatctc caaaactctc ctcttgcacg aggatcagct
    39241 cctgggtttt gattaactct agggttgcca aaaagagggt gatgacctct tggacattct
    39301 gggcttcctt gaacaaatcc tgcaagcgca attgatctcg tccaatcaag gactctttca
    39361 cgataatcat catgtcctca atcttatact catcccgcaa gatagtcgtg tgattttgtg
    39421 caaactcctc ttttttcttg gctaggatat ttgaaaaagc caaaaagagg tcaatggtcg
    39481 tcttgtcatg cacaagctcc gcatcttcgt aaatcaactc tgtcggcgct ttggaataat
    39541 actgggcccg ttcttggtgc ttggcttcca agtgctcacc caagagcttg aacttgcgat
    39601 attcttcgat ttgagagagg aggtcctgct ccaggtcatc ccccaagtct gtcacttctg
    39661 ctaccttcgg aaggagttta cgactcttaa tcagcatgag ctgactagcc atgaccatgt
    39721 actcacccgt cacttccaga cgcatggcct gcagggttga aacataggct agatactgtt
    39781 cgatgacttc cgtaatgggc acatcgtaga tatccatctg gtacttagaa accagatgca
    39841 agagcaagtc cagggggcct tcaaaatctt ttaatttaat atccattatc tatatttttc
    39901 taaggtcagg actgttttta atcctaattt ttttgcaatt tcgtacaaat cgaccttgtt
    39961 ttctatttgt cttagaataa actgttcacg taagacttga gctgataagg atggaaaacc
    40021 tttctccttg acaaaagatt ctaactgacg aaaggcccac tgacgagaat agggtttctc
    40081 tcctctttca aaaagatagg tctgccccat caagggttcc aattctgaaa gcaaggccgt
    40141 gggaatggtg acaatcctct gttgggaagc cttgctgatt cgcaacacct gaaaatccag
    40201 attgatgtcc gcaaccttga tggctaaaat ctcactgggc aagagcccca tttctaggat
    40261 taagagcgct agcaagcggc cctctggatg gtcgctttcc tgccaaaaag agtctaggta
    40321 tagaatctct ggcttttccg tcttcttttc agcttgtttg gctaattcca agcggtaaaa
    40381 gctgtccacc tctccttttt gatagagaaa gtatagaaat tggttacagg ccgaaatctt
    40441 tcgcttctgg gcgctgattt ttagattggc tagctgggct tggtaaatct tgagactggt
    40501 ctcagaaatc cgctcaccta ccatgtctaa aaattgctcc aaatcatact tataggactg
    40561 cttggaattg acagacaagc cctgcttttc ctctaaaaag gctgaaatcc tgtctctcat
    40621 tggcatcgaa tctcatattc cttactaaag tcatgcaaga gggcattaac ggccttgagg
    40681 atggacttac gcgtaataat cccttggaaa ataccctctg catccacaac cggtaagaag
    40741 gactcatcta ctagcttgtg caagacctcc gtaatggtga aatcaggcga aacaaccgct
    40801 acgtccgttt ttgtcatatg aacgatatcc gtatccgcca tgatttcttg gctcaagtca
    40861 tgctccatct gataagccat aatatctctg agtccaatcg tcccaacaaa ctgtttttca
    40921 tctgtcacaa cgggaacacg ggtataggtc atctgactga gcaagagggt cgcatgatcc
    40981 gcattgtggg tatcaatcaa cacagctaga tttttagcag gggtcaaaaa agtttcctcc
    41041 tgccccaaca agaaagtctc aaactccttg gcaatcatcg gctaaactcc ttggacaaac
    41101 ctggatacac ctcgtgatct cgtgtcaaaa agtccacttt gaagtaacta tcatcaatct
    41161 ccacacgagc atagagacat tctctgatgg tacctcgtgg ttgactgata gaacctggat
    41221 ttagaaagag gatcttgcct tccaaccaag cacttggcac atgcaagtga ccatagaggc
    41281 agatagcggc ctcttcctcc tgagcccagt agtccaactt ttgaaagttg aaattgatgt
    41341 caaacaagtg accatgagtt tggataatct tggtcgaacc aagctcagtc accagacgtt
    41401 ctgggtagcc ggcgtagaag tccatgtttc ctttaacaac gcggatgccc tcccaaagtg
    41461 gagaatccgg acgtagttca gaatcgccgt tatgaaaaac ggcatcgact ttgcccacat
    41521 agcgatcacg gacttcttcc acaatcaagc tatcgccatg ggaatcgctc attacaatga
    41581 tggtttgctt tgccatgatg gaaatacctc caaaagtttc ttaacggcta aggcacggtg
    41641 agattgacta tttttttctt ccagggttaa ttcagctgat gacttacctg tctctcctac
    41701 aaggaagagg ggatcatagc caaagccatt ttcaccctta ggttcaaagt taatataacc
    41761 tgaccagtct gcttcaacaa ctaaactttc cttatttggg ctggctacga ctagggttgt
    41821 gtggaactga gccgagcggt ccttgagttc aaagaccatg gccaattcgt gcaagagttt
    41881 ggcattattt tcacggtcag ttgctcccac acctgcgaaa cgagctgacc agacgcctgg
    41941 taagccacca aggacatcga ctttgagacc agaatcatct gccaaaacca tcttgcccgt
    42001 taattgagaa atggtttctg ccttaaggcg ggcattttct tcaaaggtca tacctgtttc
    42061 tgctacttca ggcaggtcag ggtagtcatt aagattttcc acatcgtagc ctaacttatc
    42121 aaagatagct cggaattcct tggttttgcc ttcgttacga gtcgcaatca acaaggtttc
    42181 tctgaccttg cttgtctcaa agaaatcatg aacattgacc ccttctttag gcaattctac
    42241 atacaagagt tgcccatttt caaccaagag cagggcccca tgacgttgaa taacttccaa
    42301 gtttcgtccc atttcttgat taagcatgtc taccacaaag gagaacaaac ggtaggtaga
    42361 accatagcgt aaaacagtaa ctgaaagcgg gaaaccatac tcttcatctc caaatatttt
    42421 ggagaattca aacagaggaa aatctgtctt atagtcgctc aaactgttaa cgccaccaaa
    42481 aatactataa gacccaacat accaatcctg gtcatcctta tattcataaa ttttatttgt
    42541 cataattcta catgctccac ataaatctct ttttccagcc attcttcacc aatttgtgca
    42601 aaactttggc tactggctgt tgtgtaaaaa cggtgatgga gtggtccagc atcgcgacca
    42661 cgattgattt caaaataatt gagtaagact gagatatccc gtacgcactc tgccccacta
    42721 tcgatgagct gaacctttgg ccccatgaca ttttggataa tagggcgaag gagtggataa
    42781 tgagtacagc ccaaaatcag gctatccacc tttccaacca agggacgcag ggtttcatag
    42841 accaccttct tggtaacact ggttgacagg gcacctgact caaccaaggg agcaaacttg
    42901 ggacaggcca agctctccac ctgtaagtcg ggatccagat catggatttt ctgacggtat
    42961 atgtctgatt gtaccgtcat gggcgttcca atcactccga ttttcccacc ttgactggac
    43021 ttgatggctg ccgaagctcc tggcaaaatt acacccaaga caggaatatc tagttgagcc
    43081 ttgatttctt cccagacgac cgcagtcgca gtgttacaag caatgacaat cattttgaca
    43141 tccttggtca agagaaagtt gaccagctgc caagtatatt cacgaatttg ctcagctgga
    43201 cgggggccat agggcgcccg cgccgaatct ccaatataga cgatttcttc atggggaagc
    43261 tggcgcatga gctcgcgcac aacggtcaag cccccgacac ccgaatccaa aaaaccaatt
    43321 ggtcgattat ccatacagtc ttctttctag tcttttttct gattgatcgt tcattatgat
    43381 tccttgtact gaacgaactg accgacagct tgatagaatg tcaactacct ctctcttaat
    43441 cataatcaaa tatcaataga atgcaaggaa aaagtctcat ccctaaacca taaccaacat
    43501 agtgagaagt ctggaacttt catcccagac ttttccttat ttattttttc tttttattgt
    43561 tagcaagggc tgccttttgt tggcggatga tttggtggta aacttgttgt accttagctt
    43621 cgcttggttt ttgaccattt gcactcaaaa gagtacgaac tgcttcagca ttcaaacgtg
    43681 ggttgtcagc aaattctttt tcgatttgct tacgaaccaa gtacattcct ccaagagctc
    43741 ctcctagaaa agctagcaca atcaatacaa ttgctaaaag taaatccatc atttttctcc
    43801 tgtttctttt tgagtccctt tcattatacc acaaactagc caccctgacc agtttgttct
    43861 acactttcag ggatggaata gacagcaaaa agaaccctgc ttttctgaaa aagaggtctc
    43921 cttgctaagt ttaatttaca taaatagcca gtgtttgata gggttttagt agaattttct
    43981 cagacacttc tgcatcttca tagtttgaaa tcaaaatctg tccattttgg tagactgctg
    44041 gcaagtcgat ttccacttct ttagcataaa agttattgag cactagtaac ttttgatcct
    44101 caaactggcg ttcaaaagcg tagacttgtt tgctatcttc aaaggctggt ttgtaacttc
    44161 cttctgaaat gattggcatt tccttacgca gtcgaatcaa gtcttgatag aaggtaaaaa
    44221 tcggaccctg gatttcattt tctacattga tgtctttata ggatttacca gctttcaacc
    44281 aaggagtgcc tgttgaaaat cctgcatttt ccgaagcatc ccactgcatg ggaatgcgtg
    44341 aattatcacg cgacttagct tgaataatct ggaaggcttc ttgctgactc tttccttctt
    44401 ctaggagcat ctgataggca ttaagcgatt cgacatccac gtaatcagcc atagaatcat
    44461 agtctgggtc aatcatcccg atttcctcac ccatgtagat ataaggtgtc ccacgtgaca
    44521 ggtgaatgct ggctgctagc atggtggctc cttccttgcg gaagttttga atatcgacaa
    44581 aacggttcaa ggcacgtggt tgatcgtgat tgttccaaaa gagggcactc caaccgtctt
    44641 tatcactcat ttccttaccc caactatggt aaagactctt caactcttca aaatcaaagg
    44701 gagccaaggt ccacttttgt ccatccttat agtccacctt gaggtgatga aaattaaagg
    44761 tcatggataa ttcctgacga tcaggcgacg aatagaggac acagttttcc atggtggtag
    44821 aagacatttc cccaactgtc ataaagctat cgtcagatcc aaaagtggct tggttcatca
    44881 tacgcaaata gttatgaacg atgggtttgt ctgtataagc tggcttccct tcattttcag
    44941 gacagtccac tgaaacctcg tccttaccaa tcaaattgat cacatcaaat cgaaaacctt
    45001 tgacaccctt gtcgcgccag aaattaacaa ccttgaaaag ctccttacgg acattgggat
    45061 tgcgccagtt aaggtcagcc tgggtctcat caaataggtg aagatagtat ttcccagtat
    45121 ccccgaaagg cgcccatgca gaaccaccaa acttagactg ccaatctgtt ggttggtctt
    45181 ggatgaagaa aaagtcttga taatacttat caccagctag ggctttctga aaccattcat
    45241 gctctgtcga acaatgatta agtaccatgt ccagcataaa gtcaatcttg tgctctttac
    45301 cgatacacac catttcctca aaatcagcca tatcaccaaa aagaggatcc actgccatat
    45361 aatctgaaat atcgtaacca ttatcccgtt gaggacttgg atagaatgga ttgagccaga
    45421 ccatatccac acctagtttg gctagatagg gaatttttcc gataatccca cggaaatccc
    45481 caataccatt gccagtggtg tctttgtaag attttggata gatttgatag actacttttc
    45541 ctttatcaag tgtcatctgt ttctcctttt ctgataaaag ggaggaagca gtcttccgtc
    45601 cctatttgtg ctatttcaat tatactcaat gaaaatcaaa gagcaaacta ggaagctagc
    45661 cacaggttgc tcaaaacact gttttgaggt tgcagataga gctgacgtgg tttgaagaga
    45721 ttttcgaaga gtattagatt cgtgtagcga ccatgagaga tgctccagct tgaatcgttg
    45781 tcggataagt tccgggaata gtcgctgtat aagcatcttg gttggtgatg ataacaggag
    45841 tttctgtcac cagacctgca gccttaatga catccatatc aaaacgaatc agttgctgac
    45901 caactgtaac gtgatctcct tggactacaa gactttcaaa acctttgcca tcaagaccta
    45961 ctgtatccat accgatgtgg atgagcaatt caactccctc gtcagagaca atgccgatgg
    46021 catgcttggt agggaaaaga accgtcactg tcccattaac tggagaggtc aactcacctt
    46081 ggcttggttc aatgactaga ccttgcccca tgacacctga tgcaaaaata ggatccgtcg
    46141 cttgactcaa ttctttcact tggccagtta gtgggctgat aatttctacc gaagtaagtt
    46201 ctactggttc atggttcaca aattctgctt cttcttgagc aacgaattct gcctgcaagt
    46261 tcgtatcgcc ctctgttttt gtaaagagac cagccttgcg gaagaagaaa gtcaagagca
    46321 ttggaacaac aatcgcaact agcatagttc ctgcaaatgg cagcatgtat tgaggttgaa
    46381 tagagagaat acctggcaaa ccaccgatac caatagaagc cgcagttaca ttaaaagtaa
    46441 cggataacat gcctgcaagg gctgaaccag tcatcccagc aacaaatgga taaatatatt
    46501 ttacgttaac cccaaaaaga gctggttctg taacaccgag ataggctgaa atggttgcag
    46561 gaagtgaaac ctgagcctca cgctcatcat ggcgatgcat gaaataatag gcaaacacgg
    46621 ctgagccttg agcaatatta gaaagagcaa tcattggcca tagggcagtg ccaccagcat
    46681 ccgcaatcaa ttgtgtatca atggcattgg tcatatggtg cagacctgtg atgacaaatg
    46741 gagcgtagag ggcaccaaaa attgcaccga agagccattt aactggacca gttaaacctg
    46801 ccaagacaac tgatgaaagt ccttgtccaa ttgtccaacc gattggtccc aaaacagtat
    46861 gagccaaaat caaggctgga atcaatgaca agaaaggtac aaaaatcata gaaatgactt
    46921 ctgggatatg cttgcgccag aagatttcaa gataagatag actcaaacct gcaagcaagg
    46981 ctgggataac ttgggcttgg taaccgatac gattaacagt aaaatagcca aaattccaaa
    47041 cccagtttgc cgcgatatca gctgctggcg ttgaagcaac cgcataggca ttgagcaact
    47101 gaggcgatac caaacagatt ccgagaacaa ttcccaaaat ttggctggtt cccatcttac
    47161 gagaaacaga ccaagtaatc cctactggta agaactggaa gatagcttca ccaggcaacc
    47221 agaggaaatg attaacacct gcccaaaact gagaggattc tgtgatggtc ttgccatcca
    47281 acatcgacca atggacacct tccaagacat tacggaaacc gaggatcaat cctccgacta
    47341 tcaaggctgg aataatcgga gtaaaaatct ccgccagagt ggtcatgaca cgttggacca
    47401 cgttttgatt actcttagct gcagacttgg ctgcttcttt ggaaacaccc tcaatacctg
    47461 aaacagctgt aaaatcatta taaaagatgg gcacgtcatt tccaatgatt acctgaaatt
    47521 gacctgcatt tgtaaaggtt cctttaacag ctggaattga ctcgatagct ttaacattag
    47581 ccttcttatc atttcctaaa acaaagcgca tccgtgttgc acagtgagtt acggcagtca
    47641 cattttcttt gcctccgatt gcctgaagca gatctttggc ttcttgttca aattttccca
    47701 tttgattctc cttatacttg tcaaagcaag tttgatttga taagtatatt gtaaacgata
    47761 ccaaacttgt ctgcaacttg tttggtataa aaagggtgtt tttttgtaaa ttttctagca
    47821 cttgtatggt aaaatagata caggtgttca ttaaactaga ctaaaaacct atttaagcag
    47881 gcaaaatgaa gaaataccaa caattattta agcaaatcca agaaaccatt caaaacgaga
    47941 cttacgctgt cggagatttc cttcctagcg agcacgacct tatggagcaa tatcaagtga
    48001 gtcgtgatac cgtccgaaag gccctgtctc tcctccaaga ggaaggattg atcaaaaaga
    48061 taagagggca aggttctcaa gtcgtcaaag aagaaaccgt caatttccct gtatccaacc
    48121 taaccagcta ccaagaacta gttaaagaac ttggactgcg ctctaaaacc aacgtggtca
    48181 gtctggacaa gattattatt gataaaaaat cctcactgat aaccggtttc ccagagtttc
    48241 ggatggtttg gaaggtggtc cgccagcgtg tggtggatga tctggtatcc gttctggata
    48301 cggactatct ggatatggaa ctcatcccaa atctcactcg ccaaattgct gagcagtcta
    48361 tctattctta tatagaaaat ggcctcaaac tccttattga ttatgctcag aaggaaatca
    48421 ccattgacca ctcaagcgac cgagacaaga ttctcatgga cattggcaaa gacccttatg
    48481 tcgtttcgat taaatcaaaa gtctatctcc aagacgggcg ccaatttcag tttaccgaaa
    48541 gtcgccataa gttagaaaaa tttagatttg tagattttgc aaaacgcaag aaataaaaga
    48601 ctgagacacc agatctcagc ctttttcttt atcccaaaac taattcatca ctgaccagac
    48661 tttggccact atttttctgg aagagatgca taaggtcttc aactgtcaga tgctttttct
    48721 cttctccctt gacatccacc actatcttgc cttgatagag cataatgaga cgattgccgt
    48781 actcaatcgc atgattcata tcatgggtaa tcatcaaagt cgtccactga tggtactcca
    48841 caatcttttg cgtcaagtcc atcaccattt gactggtttt cgggtcaagt gccgcagtat
    48901 gttcatccaa aagcaaaagt ttgagtttca ccagagctgc catgactagg gtcaaagcct
    48961 gtctttgtcc tcctgagaga tattgagtat ctacttttaa gcggttttca agaccaatat
    49021 tcaactcctt caaggcctct tggaactgga ttctatcctt ctccttcacg ccccaaccaa
    49081 gccctctctt ttgcccacgt ctcaaggcaa tagccatatt ctcctcaatc gtcaaacgag
    49141 aagctgttcc catcttagga tcttgaaaaa cacgggcaat atccttggct ctctttctga
    49201 cactcagatg tttaatggat ttccctgcca gtagaaggtc cccttcgtcc accgatagat
    49261 taccagccaa gatattcatc aaagtggatt ttcctgctcc atttccacca atcacagaga
    49321 taaaatctcc ctcttcaacc tctaaatcta atcctttgag gacatggttc tcattgaccg
    49381 tccctgcttc aaatgtcttg tgaatatttt caagtgttaa caaacttgcc ataactttct
    49441 cctcctattc atttctcaat ttcagaccac gaatctttaa tctcttttgc aatgctggtg
    49501 caaataaaac caaagcgagc aagattgcat taaagagacg taccaagttt tgatctagat
    49561 ttggaatttc atagatattt aaaataatca aacggtaaac aatagcaccg attccgatgg
    49621 ataataagcg gcctccaatg gtcaagtcgt gtatcaagac ttccgagctc aaaccaacaa
    49681 caatggttcc tgtcccagaa gtcacatctg aaaatccatc attttgggca aacaaggaac
    49741 cacatagggc aatcaaaccg gttgaaatca tgtaaccaac aatcttcatg gtgtttacat
    49801 tgactccatt ggcctcactc atcgggatat tgtccccagt cgaacgcaag accaaaccaa
    49861 tctctgtttt catcaaaagg gtcaaaacca aacaagtaag agacagacta aactaagtga
    49921 gaaaacagct ccttcatttg tcagacccaa gctcgccaac tgtttaaaga cggttgcaga
    49981 atctcccaag gaaagattgg gtacactgcc catgatttta atattgattg aatagagccc
    50041 tgtcaaggtc acaatccctg tcaagagagc tgggattttc atcttggtgt ggagcattcc
    50101 tgatataaga cctgctacca tacctgccag caaagcaagt aaagtcgcaa gccaaggatt
    50161 tgcccctgcc tgtatctgtg atacaacgat tgctgccccc ataggaaagg ctccctcagc
    50221 agtcatatcc gcaatatcca aaatacggaa agtcaagtag accccaattg ccataatcga
    50281 ccacaacaaa ccttctgata aactagataa cacaaaattc atcttaatcc tccttattcc
    50341 ttgccttcta acttactaat atcaattcac aatgcatctg ccatttcttg attagtatgc
    50401 aattccagtt tttcaggcaa ctcaactgct atattttctg gttcctcacc ttttaaaaca
    50461 cgaatcagca tgcgagctgt ctgtcttccc aattcttcat aattggttcc gtagttatac
    50521 aagccaccaa cagcaatcat ttctgttgaa ccaccgaata ctggaacctt gtgtttaata
    50581 gaaacctgct taactgtttc catggttgac gaaatgatat tatcagttgg gacaaaaacc
    50641 atatccacct ctgccatcaa actctctgct gccgccttga cgttattact gtccaagatt
    50701 gttttttcaa caacggtaaa gcctttttct ttcagaaatc gcttagcttc atccttttaa
    50761 acaaccgaat tgggctcgct ctgagtatag aggattccaa tcgttttagc ctttagcaac
    50821 actttcttta tcaaattgat ttgggttgaa atggcatctg atgactgatc gcttgtccca
    50881 gttacattgc ccccaggatg ttctcttgac tcaaccaact tggcactgac tgggtctgtt
    50941 acagctgaaa agataactgg tgtcgtttgc gtcgtattgg ccaagctctg agcagaaggc
    51001 cttgcgatgg ctagaacgac atcgctggat tctgctagtt gctgggaaat cgtttttaga
    51061 tttctttgtt ctccctgtgc attttgcaaa tcaatctcaa tattttcccc ctcaacatag
    51121 ccttgtttgg ccagctcatc cacaaatcct tctctagtag cgtctaagga ctggtgggta
    51181 ataaactgcg aaataccgat acgaaagaca tctcttttct tatctgcctt caactgatgc
    51241 aaactgatca gagaagtcaa gaggatcccc actaccaaga gggggctagt gattttcgaa
    51301 caactttcat aatgaaactc cttctcagaa aagataaaac aaaaaaacgc ctagatacta
    51361 tctaaacggg tacttgaaat aacctaacaa gttacaactt agctggtcca tttagatatt
    51421 catctatatg gaccacaatc aaaaatctta gccacataga tacaaacaaa ttgcttgaac
    51481 tgtttgcatc catggtgaca tgtctacaaa cactatctaa agtagctaaa gtaaaagttt
    51541 tgattcatag ttacggcttg tctcttattc atttcttttt ctgctttctt ttttgatcct
    51601 tcctatccta ccaccttttt catcacctgt caataatatt tcaaaatttt ttaaaatttt
    51661 tcgaaaattc tttcag
//
LOCUS       DAVBEM010000007        48474 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVBEM010000007 DAVBEM010000000
VERSION     DAVBEM010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48474
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.007"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(308..1474)
                     /gene="recA"
                     /locus_tag="VQ548_000450"
     CDS             complement(308..1474)
                     /gene="recA"
                     /locus_tag="VQ548_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HET2653363.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            complement(1529..2785)
                     /locus_tag="VQ548_000451"
     CDS             complement(1529..2785)
                     /locus_tag="VQ548_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HET2653364.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNLLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQVDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGISSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(2869..3885)
                     /locus_tag="VQ548_000452"
     CDS             complement(2869..3885)
                     /locus_tag="VQ548_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET2653365.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEKALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(3893..4411)
                     /locus_tag="VQ548_000453"
     CDS             complement(3893..4411)
                     /locus_tag="VQ548_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2653366.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(4401..4844)
                     /gene="tsaE"
                     /locus_tag="VQ548_000454"
     CDS             complement(4401..4844)
                     /gene="tsaE"
                     /locus_tag="VQ548_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HET2653367.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(4930..5550)
                     /locus_tag="VQ548_000455"
     CDS             complement(4930..5550)
                     /locus_tag="VQ548_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653368.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(5933..6796)
                     /locus_tag="VQ548_000456"
                     /pseudo
     CDS             complement(5933..6796)
                     /locus_tag="VQ548_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            6961..7155
                     /locus_tag="VQ548_000457"
     CDS             6961..7155
                     /locus_tag="VQ548_000457"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653369.1"
                     /translation="MKKKRVSRMKKNRGIQKLAILVLLGVFMFSNTIPYQQFIQKNRQ
                     LEIRVQSQKKSNGLDVGKAD"
     gene            7470..7766
                     /locus_tag="VQ548_000458"
     CDS             7470..7766
                     /locus_tag="VQ548_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000911560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET2653370.1"
                     /translation="MLKFRKVVASSLAVLAFSLALPVLAVSHRGGEWTYGGHHDPNNW
                     GAFSNYYHGSQYHWAYVGSNGRNNQKTVYAGARSAAYAFVNTNFGEQVTFDAGW"
     gene            7869..9884
                     /locus_tag="VQ548_000459"
     CDS             7869..9884
                     /locus_tag="VQ548_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2653371.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFIALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAGLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            9886..10518
                     /locus_tag="VQ548_000460"
     CDS             9886..10518
                     /locus_tag="VQ548_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2653372.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLTYLDLDKRIFELSGGESQRVALAKVILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDRLK"
     gene            10659..10937
                     /locus_tag="VQ548_000461"
     CDS             10659..10937
                     /locus_tag="VQ548_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HET2653373.1"
                     /translation="MKKFDNYIVEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(11446..11859)
                     /gene="ndk"
                     /locus_tag="VQ548_000462"
     CDS             complement(11446..11859)
                     /gene="ndk"
                     /locus_tag="VQ548_000462"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HET2653374.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(11970..15647)
                     /gene="rpoC"
                     /locus_tag="VQ548_000463"
     CDS             complement(11970..15647)
                     /gene="rpoC"
                     /locus_tag="VQ548_000463"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HET2653375.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGEVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPYAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(15680..19291)
                     /gene="rpoB"
                     /locus_tag="VQ548_000464"
     CDS             complement(15680..19291)
                     /gene="rpoB"
                     /locus_tag="VQ548_000464"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET2653376.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSSLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            19707..19777
                     /locus_tag="VQ548_000465"
     tRNA            19707..19777
                     /locus_tag="VQ548_000465"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19739..19741,aa:Cys,seq:gca)
     gene            complement(19975..21306)
                     /locus_tag="VQ548_000466"
     CDS             complement(19975..21306)
                     /locus_tag="VQ548_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HET2653377.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFNVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(21597..22421)
                     /gene="endA"
                     /locus_tag="VQ548_000467"
     CDS             complement(21597..22421)
                     /gene="endA"
                     /locus_tag="VQ548_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HET2653378.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLSQKKQ
                     APEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(22460..22648)
                     /locus_tag="VQ548_000468"
     CDS             complement(22460..22648)
                     /locus_tag="VQ548_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET2653379.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDSW
                     AILSPAKWQELIHKFTGN"
     gene            complement(22641..23924)
                     /gene="murA"
                     /locus_tag="VQ548_000469"
     CDS             complement(22641..23924)
                     /gene="murA"
                     /locus_tag="VQ548_000469"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET2653380.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(23948..24178)
                     /locus_tag="VQ548_000470"
     CDS             complement(23948..24178)
                     /locus_tag="VQ548_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HET2653381.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTAENTRKVRV
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(24236..25273)
                     /locus_tag="VQ548_000471"
     CDS             complement(24236..25273)
                     /locus_tag="VQ548_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HET2653382.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(25257..25745)
                     /gene="coaD"
                     /locus_tag="VQ548_000472"
     CDS             complement(25257..25745)
                     /gene="coaD"
                     /locus_tag="VQ548_000472"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HET2653383.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLCVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(25735..26274)
                     /gene="rsmD"
                     /locus_tag="VQ548_000473"
     CDS             complement(25735..26274)
                     /gene="rsmD"
                     /locus_tag="VQ548_000473"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HET2653384.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKTVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(26339..27331)
                     /locus_tag="VQ548_000474"
     CDS             complement(26339..27331)
                     /locus_tag="VQ548_000474"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HET2653385.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(27443..28126)
                     /locus_tag="VQ548_000475"
     CDS             complement(27443..28126)
                     /locus_tag="VQ548_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HET2653386.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(28182..28922)
                     /locus_tag="VQ548_000476"
     CDS             complement(28182..28922)
                     /locus_tag="VQ548_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HET2653387.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            28956..29234
                     /locus_tag="VQ548_000477"
     CDS             28956..29234
                     /locus_tag="VQ548_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HET2653388.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            29312..30238
                     /gene="yidC"
                     /locus_tag="VQ548_000478"
     CDS             29312..30238
                     /gene="yidC"
                     /locus_tag="VQ548_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET2653389.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(30313..31107)
                     /gene="pflA"
                     /locus_tag="VQ548_000479"
     CDS             complement(30313..31107)
                     /gene="pflA"
                     /locus_tag="VQ548_000479"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HET2653390.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(31233..32483)
                     /locus_tag="VQ548_000480"
     CDS             complement(31233..32483)
                     /locus_tag="VQ548_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HET2653391.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(32550..33377)
                     /gene="purR"
                     /locus_tag="VQ548_000481"
     CDS             complement(32550..33377)
                     /gene="purR"
                     /locus_tag="VQ548_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HET2653392.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLHEFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(33644..34585)
                     /locus_tag="VQ548_000482"
     CDS             complement(33644..34585)
                     /locus_tag="VQ548_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HET2653393.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(34575..35831)
                     /locus_tag="VQ548_000483"
     CDS             complement(34575..35831)
                     /locus_tag="VQ548_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HET2653394.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(35833..36495)
                     /locus_tag="VQ548_000484"
     CDS             complement(35833..36495)
                     /locus_tag="VQ548_000484"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HET2653395.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDGFVGVDRGSLWILE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFKQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLASYMHQIEIEDGQNLITYCPEGISQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(36458..37114)
                     /locus_tag="VQ548_000485"
     CDS             complement(36458..37114)
                     /locus_tag="VQ548_000485"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET2653396.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDGHFVP
                     QISFGAGVVEALRPHSKMVFDCHLMVSNPEHHLEDFVRAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALRDEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(37125..38003)
                     /gene="rsgA"
                     /locus_tag="VQ548_000486"
     CDS             complement(37125..38003)
                     /gene="rsgA"
                     /locus_tag="VQ548_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HET2653397.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDGGELDFYQQTYGDIGYDFVTSKEELLPLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     TAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGTIAPFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(38596..39369)
                     /locus_tag="VQ548_000487"
     CDS             complement(38596..39369)
                     /locus_tag="VQ548_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HET2653398.1"
                     /translation="MRKKLVNSLMCAVVLSGFPIATYANEKNIGPNITVSNGQTRLSI
                     PEKNGVEVIQSEENRVVYEVKEAAKIETSDGDMVAPIVVDSRITSINNQVVQGKTVYT
                     ADLEKATFVEEGYNKLAKPTNILDHIFGIQKVHAYTQNITTHQSQFDSTYSVELYTVV
                     HWVSYDGGVQKNITKISGGVDFHERDIEIESSSVEVRQGGWYSSQQKWFHPGARSSWE
                     YSTGFSKVGPGENRVVTNYTVNLIRYGDRWSAYLQNNPW"
     gene            complement(40059..40931)
                     /gene="rsmA"
                     /locus_tag="VQ548_000488"
     CDS             complement(40059..40931)
                     /gene="rsmA"
                     /locus_tag="VQ548_000488"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HET2653399.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAEVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPVPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLE
                     EFASLADALKGQGL"
     gene            complement(41182..41400)
                     /locus_tag="VQ548_000489"
     CDS             complement(41182..41400)
                     /locus_tag="VQ548_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653400.1"
                     /translation="MENMTNPLLLVQIRVHGYLLDFASSEGQRQKHYRLKNLPQTVEL
                     TVDDVEEDVDLTLPENRSYQEADFFDTQ"
     gene            complement(41468..42109)
                     /locus_tag="VQ548_000490"
     CDS             complement(41468..42109)
                     /locus_tag="VQ548_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2653401.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(42111..44141)
                     /locus_tag="VQ548_000491"
     CDS             complement(42111..44141)
                     /locus_tag="VQ548_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2653402.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEVLSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQFICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSTYYQRLFTDYL
                     QNFSSESVEVTSQKYYLPQVSLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(44410..45309)
                     /locus_tag="VQ548_000492"
     CDS             complement(44410..45309)
                     /locus_tag="VQ548_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2653403.1"
                     /translation="MLIGQKIKEIRIEKGVSRPYFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(45381..45941)
                     /gene="rnmV"
                     /locus_tag="VQ548_000493"
     CDS             complement(45381..45941)
                     /gene="rnmV"
                     /locus_tag="VQ548_000493"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HET2653404.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINAQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVRHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(45941..46714)
                     /locus_tag="VQ548_000494"
     CDS             complement(45941..46714)
                     /locus_tag="VQ548_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HET2653405.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     RALELVDEYDQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKVTDLQEAAKELPLDKILVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(47019..47912)
                     /locus_tag="VQ548_000495"
     CDS             complement(47019..47912)
                     /locus_tag="VQ548_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET2653406.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLENTPGGDKGGNTGSSDANANAGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIVMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(48196..48330)
                     /gene="rpmH"
                     /locus_tag="VQ548_000496"
     CDS             complement(48196..48330)
                     /gene="rpmH"
                     /locus_tag="VQ548_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HET2653407.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
BASE COUNT        13991 a        10914 c         9042 g        14527 t
ORIGIN      
        1 taaagctatt atatcagctt tccagaggag cgacaagaaa cagcaaactt atatatagcg
       61 gaatgaaata aggaaagtca aatcgatttt taacaatgtt ttagaagtag atatgtacta
      121 ttctagtttc gatctattat agttggttga gtttggaata gtacgctgta gctgctaaaa
      181 catttctaga aattaatttg actttcctaa tagagttgtt catatcttat ttcaagctac
      241 tatatataat ctaaaaactt gaatcaaaaa tcgaaaaagt agcggatttc tccactgctt
      301 taacagctta ttcttcaatt tcgatttcaa gttcatcgcc taagtcaagc ggaacttctt
      361 cattcactgc ttcttctttc tttggctcat cttttttgtt ttcagtatct tgttctgaaa
      421 cttcttctcc atcaatcaag ccaaatttag aacggacttg cttatcaatt tcatcaaaga
      481 tttctgggtg ctctgccaag tatttcttag cattctcaga accttgccca attttttcat
      541 ctttgtaaga ataccaagcc cctgcttttt tgataatatc caaatcgctt gcaatcttca
      601 aaagctcacc agtcttagaa attccttctc cgtacataat ttcaactacg gcttccttaa
      661 acggtggagc taccttattt tttacaacct taatcttagt ttctttaccg acattggttt
      721 ctttttggtc accagttccc ttaatttgtg tattaccacg aacatccaag cggactgaag
      781 catagaattt caaagcacgt ccgcccggtg ttgtttctgg atttccaaac atcactccaa
      841 ctttttcacg caattggttg ataaaaatgg caattgtttt ggttttattg atagaggcgc
      901 caagtttacg catggcctgg ctcatcatac gagcctgcaa accaacatgg ctatctccga
      961 tatctccatc aatttccgca cgaggaacaa gggcagcaac tgagtcgact acgacaagat
     1021 caactgcacc tgagtcaatc aattttcccg caatctcaag accttgctct cctgagtctg
     1081 gttgagacaa gagcaattcg tcaatattga caccaagggc cgcagcataa gctggatcaa
     1141 gggcatgttc cgcatcgata aaagcagcaa tcccaccttc tttttgcgct tgtgcaactg
     1201 catgaagggc aaccgttgtc ttaccagatg actctgggcc atagatttcg atgatacgtc
     1261 ccttaggata accacctgag ccaagggcaa tgtcaagagc taaagaacct gagctcatca
     1321 cttgcacctt ttgctccgca cgttcaccca aacgcatgat tgatccttta ccaaagtctt
     1381 tctcaatcaa tttaagagcg tcattcaagg ccttttcacg ttctgcccca aatttttttg
     1441 aaatttcttc taattttttt ggttttttcg ccattctatt ctcctacatt ctaatgatcc
     1501 tcagacctat ctactattat atcaaaaatt agtcacttaa taaagccttg cgaactaggt
     1561 taaaggcatg cataaccgca atgtgacgta catctgctcg gcttctgcct ccaatattaa
     1621 ccttgataac ctcagttcct tgatcttgcg ccaagcctat gaagactgtc ccaactgggt
     1681 gtccttctag gctatctggt cctgccactc cagtcaaact aattccaaaa tcagactggg
     1741 tcttgcttcg tgcctgctca gccatcttct gagctgtaaa ttcagacacc acaccatgtt
     1801 cttccaaatt cttggcagga atatccaaca tccttgattt ttcctccaag ctataggtca
     1861 caaaaccacc cttaaatata cttgaaattc cagaaaaatt cgccacggta gcttggaaaa
     1921 gacctgccgt caaactctct gcagccgcga tggttttccc ttgccttttc agttcttcta
     1981 ccacaatgct ggctaaacta gtttcttccc cataaccata gcaaaagtct cgtaaagaaa
     2041 ttccttcgaa agtctggcag tccaagattt gattttccaa gatatccagc gcttgattcg
     2101 cctcttcttg actgctagcc tttgttgaca gacgtagagt gacttctcct gtcttggcat
     2161 aaggggccaa ggtaggatcg acctgattat caattaaatc agccaaaatc gtaaccagct
     2221 ggctctcgcc aatcccaaag aaacgaagaa ctcgggaata cagcttgctc cctgtcatca
     2281 acttgggtag aagtaggttt aagaccatgg gtttcaattc acttggcgga cctggaagga
     2341 cgacataggt cactccgtct acttctaatt ttcctccaac agccagtcct gtttcgtttg
     2401 gcagtggaat cgctccttct acaatttgag cttgtctttc gttattcggt gttcgggcat
     2461 agtctggtcg cagggcaaaa aagatatcca acttctcctg agcctgagga tcaaagacta
     2521 atgctttccc taaaaattta gctagggttt gtttggttag gtcgtcctca gttggcccca
     2581 aaccgcctgt caaaatcacc agactgctac gttgactggc aatctcaagc aaagacaaga
     2641 gacgaacttc attgtctcct acagccgtct gaaaatatac atctacccca atctcagcta
     2701 gtttttccga caaaaactgg gcattggtgt tgacaatctg tcctgtcaaa atctctgttc
     2761 caacagcaat gatttctgct ttcatgtttc ctcctaccta tctattcgta tttttttgaa
     2821 aaaatcgcag gaattttcct acgattgatt ttttatttgt atcaaaagtt aattatcttc
     2881 atcaccaaca ggtgctctgc caaataaatc ttcaaataaa accgcattgg tttcaagctg
     2941 agtaacttct tcttgtccca aagaacgtcg gagtatattt tgcatttcca acatatgtgc
     3001 tcttgaaaca atctggtaag aaacaccttg aagtatctct ccttcaccct gcaactgctg
     3061 agtttcaatg gttttaaatg aatctttata gcctagcaag ttagggatac tttttgcaga
     3121 caaatcaata ttggtctgca tattgtcact caaagctttt agaatctctt gataatgacc
     3181 aacgctattt aaactgagag ctttttccat gactttttga ataacttcac gttgacgttt
     3241 ttgacgacca taatccccct caggatcttg gtaacgcatt cgtgcataga ctagggcttt
     3301 ttctccccca atatgttgct ccccaacacc gatagaaata gtattaaatt cttcttggtc
     3361 actgatagaa attgggaaac ctaggatatt attgactgta atacctccta ctgcatccac
     3421 tagtttttgc aaccctctca tattgaccat cacatagcga tcaatatgga tattcatcat
     3481 tttttgaatg gtttctatag caagctctgc tccaccatct gcatatgctg agttcagttt
     3541 cgcttcatga gcctgaccat tccctgattc aatgcgcgtc agaatatccc gctctaaact
     3601 catcattgtt gtttttttcg ttttaggatt cactgtcatc aagatcatgc tatcacttct
     3661 accgacccaa gtttcagttc gttcaacatt tccggtgtcc actcccatta acagaatggt
     3721 tagaggttca gtcgcttcaa taaccttggt ttcttcgccg atttttttat aggttttagc
     3781 taaggtttct gtcccttgtt gataaatagt ataagcaaaa acacctactc ctactacagt
     3841 tacagaaagt aaagctagca ccattccaat aattttttta accatatttc tactaaccta
     3901 tcagtttacc catcaagtaa acatcgataa atttcccttc ttctatatat gccccacgct
     3961 cttggctacc ttcaatgaca aagccatgct tttgataaag atggactgct gcttgattac
     4021 gagtttggac agtcagttgg agacgacgca gaatgccact tgcttgtgcc cactctatcg
     4081 cttcttctag caacaaactt cccaagccat tattccaata tctttttcca atcacaatga
     4141 agagatctcc aatatgacgg actctcttac gctgatcagc tgtaatattt acaataccag
     4201 caattttgcc atttaagaat gcaagtaagg ttatctgatt gtccgaacta gcttgcttgt
     4261 tgaggaatat ttccatctcc tcactagtca agagaatacc atctccgtct aggctggtaa
     4321 agtctgtctc caaactcaca cgatttaaaa aggccactaa ttcagctgca tctttgggct
     4381 ctgcttccct aatgagcaat tcatactcca tattgaagct cctctaacaa tttctcagca
     4441 cgcaaaccct ttgcctgaaa atttaaacgg cgtccatctg cttcttttag aatttccaat
     4501 tctaaataag catctggcaa ggcatctcct aagagatttc cccactcaat aacagtcacg
     4561 ccgccaccaa agataaactc atccaagtcg atagaatcag catctccttc aatacgataa
     4621 acatctaggt gataaagtgg aagtcgacct tcatactctc tcacgatagt ataggtggga
     4681 cttttaatca tttgagaaat ctgtaatcct tttgcaagtc ctttagtaaa ggtcgtttta
     4741 cctgcaccca gttctccagt taagattaaa acatcattct ttgctaatag atggcccaaa
     4801 cgctccccta aggcttgcaa ctcttcttca ttttttgtgt acatactctt attataccaa
     4861 aaacttttct tttgtgtcta ttttcctact aaacttatca tcataacatc cataaaaaac
     4921 aggctttctc taaaagaaaa tgagcgtaac aatgaccaat acaagatctc ggaaaatatg
     4981 accataaaag gaaacttcct tcttaaccga atttgggaca agataggctg caaaaaacaa
     5041 gcccagtcca atataaatca gaagtgagac aatggtcatt ggatttctta agaaaagaag
     5101 tgttgctaaa atagtcacca acactgtctt ttttctgtct agcatagcaa gaaaatcgcg
     5161 cacgtatttt ttcaagggta aaaaaatcag caaatctagc ccaaatagga aaaagaagga
     5221 tggcaataaa aagtcaacta attcttgctg cagcgtattt ttgatgaaca agttatctga
     5281 caaaacaaga acagctccta acaaattaat taagagtaac atactgtaaa aaagcttcac
     5341 cgacttctta ctggctagga cactatggac ttcttgctta cgggtataaa gataatttac
     5401 tccagcacag attcctgaaa cgaaaaccat gctcccgatg aaaaaagctg tactttgttt
     5461 aaaggacaag atgcattcct tccataggaa acagctactc aaactgattt gaattaaagc
     5521 taacaaaaat aagattctca ttgatttcat cttctctctc ccttcctacc aatcattata
     5581 ctaggagaaa agagagaact gtttctaatc ttctcaaatg tctctttaag acgctaaaca
     5641 aacactagag actaatactc aatgaaaatc aaagagcaaa ctaggtagct agccacaggt
     5701 tgctcaaaac actgttttga gattgcagat agagctgacg tgatttgaag agattttcga
     5761 agaatataaa tttgaaatca tgaaaatccg tcaaacgggt ggttgttttg tctcgcacct
     5821 cacggagcga gacggactca gagtcacata attataaggc tgatagtatt aatctaacta
     5881 tcagccttac aggttattta acgtttcaga aaaactataa tgtcaagatt aactaaacag
     5941 tatctaattc cttcaaataa ttttctatct tcatcagcat taaaggattg ttataaatct
     6001 tgcatagctc tcttgcttct atataataat ttttgacttg ttctctgtct agaaatttgg
     6061 ctccagcatt tcctacaaga ataagtagag gagccaattg gtagcttgtc tgtctttgtt
     6121 tacagagttc gatagtctca agagcttctt ggatggcttc attatatttt tcctttgata
     6181 ctaggtagtg agcgtaattg taacgaactc tgatgtagcc aaataaaaac tcttgatgct
     6241 caaaattttt tgtctgatat aactccatca aatgagagta gtttacctca tattcttgtt
     6301 cacgacccac taaggaatag aaattagata gagtattcaa cgcctttaaa taaatcaaag
     6361 tatttgagga gacttttaat aatatatttt ccaatgaaga aattgcttca cacttactgt
     6421 catattgaca gaagtcaata atagctttaa tccattcaag gtaagttcgg tcttctagtg
     6481 ttagaaaagt acttcgttca atctctattc tataaatata ttccaaattt tcataatttc
     6541 tatcatctaa taggcgagca gataattgct tgaaattaga gaggttagat ttaatttcaa
     6601 tttgttcatt aaaaaaataa tctaatggca cttcgagtcg ttgtgagagt ttgaacaaaa
     6661 ggtctgcgga gggaatgaaa taccctctct caattttact aatctggctc tattcacaaa
     6721 ttccttctgc aagagtttgt tgggagagtc tcaactcttt tcttttcaat ctgaatttct
     6781 ctgcgagtgt attcattaaa gataataaac cttcctattt gcttaatttc attataaaat
     6841 ttttagttca aaatagcaag ttaaaggaat aaataattct ttgcggtaat aaacaaaaaa
     6901 aagtcaaaaa ttacataaaa atgcttggct aaataaaata tatttgttaa aataaggata
     6961 atgaaaaaga aaagggtttc acgaatgaag aaaaatcgtg gaattcaaaa attagctata
     7021 ttagtattac taggtgtttt tatgtttagt aacacaattc cttaccaaca gtttattcag
     7081 aagaatagac aattggagat tcgagtccaa tcgcaaaaga agtccaatgg tcttgatgtt
     7141 gggaaggctg attgatttta tattacttta aaattcaact atttagagaa aggtattctg
     7201 atgagagctt gtaacaatac cagatagata taagaatgga gatgtttgat aaaatgcttt
     7261 catagctaac caactgttga aaattatgag ttacaaaatc taaagtattt aagattggtt
     7321 tataaaatta ggtctctgcc tgtagaaagg aacgtgcagt tagaaaggag gaaaaaatag
     7381 gatactataa ttcagactga gatttctaat taaaatatat agttgcattt cgctcatttt
     7441 cataatattt cattcagagg agtaataata tgttaaaatt tagaaaagta gttgcatcat
     7501 cccttgccgt tttggcattt agtttggctc ttcctgtttt ggcagtttct caccgtggtg
     7561 gcgagtggac ctatggaggc catcatgatc caaataattg gggagcattt tcgaattatt
     7621 atcatggttc acagtatcac tgggcctatg ttggaagtaa tggacgtaac aatcaaaaaa
     7681 cagtttatgc aggagcacgt agtgcggcct atgcgtttgt taatacaaat tttggggagc
     7741 aagttacatt tgatgcggga tggtaaagaa taattgaaga agattctttt atcaatagtt
     7801 cagtaagctt gttagtttat agagggcagg ggtatttctg ccctctgttt tagaataagg
     7861 aatgcactat gaaaaaatta tttatactca tatccaacct gcttgctagt ttgttctttg
     7921 tttgggtatt taccatttgg actgatacat atgtctccta ttattacccc aacgttgttg
     7981 tacatgattc ttcccctgaa acaacttttc agcatgttgc tacacgcttg gaaaaactag
     8041 cagaagaaac agatagcttt attgcgattc aacaccaaga tcctaactca gaaggtacta
     8101 cagttttttc ttatacgacc tttggggacg gaaagttgcc tgatgggctt caggaaaaaa
     8161 aactagaaga tgctcaaagt agtagtgttg aaacaaacta ttttgtattc gatggacacc
     8221 tagatattca cttgctaagg gaggagctaa gtcaacttgg cttgactaac atgaacctga
     8281 caattccatc taaactatct acgttaatgg ctatctttag taacggattt cagttaatca
     8341 gtctattgat tttcatctta acctttatag cactgacttt aattagtcaa attagccaat
     8401 tacggtcgtc gggcattcgc ctcatttcag gagagaaacg gtggtccatt ttccttagac
     8461 cagttggtga ggatttgaaa gggatagctg ttggtttcag tttagctggc gtgctcgcca
     8521 ttcttatgca aaaaattctg tcgcttccaa cgcaatccct aatgaccata ggagcaggct
     8581 tgctcagtta taatctcatc ttgttgtcga tctccctgtt tttcgctcaa ctcttcgcag
     8641 ttgggataaa aaagatacac ctgatgcaga ttataaaagg gcaagtgcct gtcagaggaa
     8701 tcattagttt gattttaatc ggtcaactat tagcgattat tattgtaacg ctgggaatag
     8761 ggagtagctt aaagtattcc caagcctggc aacagcatcg gattggacaa gaggcttgga
     8821 gtcaggaaag gcaactgatt accctatcaa tcagccgtga aggaacgagt cctggttttg
     8881 atgaacaagc tcaaaggaaa ctcagaactt ggtatcaatt gatggatctg gctgtttcag
     8941 aacaaaaggc tttcttatct agacaccagt taattgaccg tactttgcaa aatggcatgg
     9001 cttcctccaa aaacttgata acctctacag aatggcacga ttacaacccg aatggcaatg
     9061 tccttatcgt cacaccgcaa tacttggagc gtcaaaacat tcctgtagat acaactattg
     9121 agcaaaagat gaatcacctt gatgtagggg agtttgtctt attgctgcct gaacacctcc
     9181 gttcagagga agaacattat aaatctgttt ttgaagacga cttaaccagt cgcatgtcta
     9241 gtcaagatga acgacagcaa atgactgcta cggtaggtta tttagaatca ggtcaggatc
     9301 gttttgtgta taatacgacc cctatttctt accagcagtt tttgaaagat ccaatcatca
     9361 ttgttataac accccaatca actggtccac agtccatttt gttttggata gacgcagtac
     9421 agaactacgt tctctttaat caattgtctg atgcccagga gcttatccag agacaaggca
     9481 ttgaaaattg ggtctcagaa atgcaaacag gttaccacaa ctacatcaca ttattggata
     9541 atattcagag ggaacgttgg gtaatgctag caggagctgg gcttgggatt gcaacttcaa
     9601 tcttgttgtt taacactatg aataggctct actttgaaga atttagacgt gccattttta
     9661 tcaaacgcat tgcaggtctc aggttcttag aaatccatcg cacttatctc tttgctcaac
     9721 tgggtgtgtt tttactggga tttgttgcga gtgtatttct tcaggtagag ataggagttg
     9781 ctttcttagt cttgttactc tttactggtc tatctctttt acagttacat gtccaaatgc
     9841 agaaagaaaa caagatgtcc atgcttgttt tgaagggagg ttaatatgat tgaacttaaa
     9901 caggtgagta aatcttttgg agaacgagag ttattttcga atctttcaat gacatttgag
     9961 gctggaaaag tctatgcctt aattggttca agtggtagcg gaaaaacaac cttgatgaac
    10021 atgattggga aattagaacc ttatgatggg acgatttttt accgaggtaa agacttggcc
    10081 aattataaat cgagtgattt tttccgtcac gaattgggct acctcttcca gaactttggc
    10141 ttaattgaaa accaaagtat tgaagaaaac cttaagctag gtctcattgg tcaaaagttg
    10201 agtcggtcgg aacagcggtt gaggcagaag caggctttag aacaggtcgg cctgacttat
    10261 cttgacctag ataagcgcat ctttgagtta tcgggcggag aatcgcaacg ggttgccttg
    10321 gcaaaagtta tcttaaagaa tccacccttt attctggcag atgagccaac agcttcaata
    10381 gacccagcaa cttctcagtt gattatggag attctgctat ctcttcgaga tgataatagg
    10441 ctaatcatta tcgcaacaca taatccagca atttgggaga tggctgatga agtgttcacg
    10501 atggatcgtc tgaaataaaa atccttgttt ttaattgcac gatgagttac tgaaatatta
    10561 tcatgaatca ataattggag ttaatttaga attgtacttt attaatattg aggtaacttt
    10621 ttcttgataa aggaagaaat agtggagagg aagttagaat gaaaaaattc gacaattata
    10681 ttgttgagaa gccttgcgat tctaattcag ataaactgca aaaaatctta ataattgaaa
    10741 atttggtaga tgatattttg caatttcctc tcagaatcaa taatagtgta ggagagattt
    10801 tcctcctaca accgtttcaa aagaaaacta tctttattcc atgttatttt gaggaagata
    10861 ttgtgaaagt caaagatgat gataaagttg agtggaattt gttagaattt caaaaattta
    10921 gagcattttt ggcttagtaa tctgtgttga aggctcaaaa cctatggtaa aaaagtcgct
    10981 ttgaaaacgt attgcctcca aagatttagt taaataatga tttaacacaa aaagaaatta
    11041 ttgaagttct ggaaagatgt tgtttcagta ttgagaaaag gtgggaaaaa cttgcgattt
    11101 tcacagagaa aggaagaaaa agtatagaaa tatagtcaat tgaaacaaga acaggacaaa
    11161 agaacctttt gtgccatatt tttctccttt cgctttacaa ttggcttgaa cacctttatt
    11221 gtatcgcgtt tggagttttt ttggtataac cttcgacgcg cacccgcata gcgggtgttt
    11281 ttttgtctcg cacctaacgg agcgagacga actaatagtc acttaatcaa aaaacgcacc
    11341 atatcaaaaa ctaaaaagtt tgatatcatg cgtcatgtct taaactaatt gactatactt
    11401 tctattcaaa tgagctttta accaattgat tgagccaatc cactcttaaa accaaagagc
    11461 aatttctcgc ttagctgact cttctgaatc tgaaccatgt acaacatttt ggataacctc
    11521 attttctcca gcagcttttg caaaatcacc tcgaatagtg cctggtaaag cttcttctgg
    11581 acgagttgca cccatcatgg tccgccaagt ttcgattact ttgggaccag aaatgacacc
    11641 cacaagaact ggacctgaag tcatgaattc acgaatcggt gggtaaaaac tctgaccaac
    11701 caagtcctga tagtgctggt caatcaactc ttctgaaact tgtgaacgaa actccaattt
    11761 ttcgattgta aatccacgtt gttcgatgcg ctttaacact tcacccacta gccctctttt
    11821 tacaccatct ggtttgatga taaagaatgt ttgttccata cccgtctcct ttgtcagctt
    11881 ctttctttta ttttaccaca tttcgtggaa aaatggagaa agttttcaga atagagaatg
    11941 agagaacccg agggttctct cattctctat tattctactg tttcttccac agtttcaacg
    12001 gcagtatcca caactacttc tgttgtttct tcatttcctt cttcctctac tggaggatta
    12061 aggtattctt cttcgttgac agcatatggt tcaaggttac ggtaacgggc cataccagta
    12121 ccagctggga tgatcttacc gatgataaca ttttctttaa gtccaaggag atggtctttc
    12181 ttaccacgga tagctgcgtc agtaaggaca cgagttgttt cctggaagga agccgctgac
    12241 aagaaactgt ttgtttcaag tgaggctttg gtaattccca taaggactgg gcgacctgtc
    12301 gctggaactc cacctgcgat aaggacatct ttgttggcat ctgtaaagtc attgatatcc
    12361 atgagggtac ccatgagaag atctgtatca cctggatcca tgacacggac tttacggatc
    12421 atttgacgaa ccattacctc gatgtgtttg tcaccgattt ctaccccttg gctacggtaa
    12481 actttttgta cttcaccgag aaggtacgtt tcaactgaca agacatcacg aactgcaagg
    12541 agacgttttg gttggataga accttctgtc agagcagcac cacgcgctac ttggccccca
    12601 acttcgacac gcatacgagc tgtaaatgga acgacatatt caccttcgcc agtttcaccc
    12661 ttaacaaaga ctttcttggt acgagttgat gcatcttctt cgatagcagt aacttctcct
    12721 ttaacctctg tgataaccgc ttccccttta ggattgcggg cttcaaagat ttcttggaca
    12781 cgaggaagac cctgagtgat atcggtattt gaggcaaccc cacctgtgtg gaaggtacgc
    12841 attgtaagct gtgtaccagg ttccccgata gattgggcag caatggtacc aactgcttca
    12901 ccaacttcaa ccgcatcacc agtcgccaag ttgataccgt aacagtgacg gcagacaccg
    12961 tgacgagtgt tacatgtaaa tacagaacgg atagtcactt cttccacacc agcattgaca
    13021 atttcacgcg ccttgtcttc tgtaatcaat tcatttggac caataatcac tgcaccagtt
    13081 tctggatgtt taacagtttt cttagtgtaa cgaccgttga gacgctcttc gagagactcg
    13141 atcatctctt ttccttctgc gatagaacgg atcaagagac cacggtcagt tccacagtcg
    13201 tcctcacgga tgataacgtc ttgggcaacg tcgaccaaac gacgagtcaa gtaacctgag
    13261 tcggctgtct taagggccgt atcggtcata cctttacgag caccgtgagt tgagaagaac
    13321 atttccaata ccgacaaacc ttcgcggaag tttgaaagga ttggcaattc catgatacgt
    13381 ccattcggag cagccatcag accacgcata ccggcaagct gtgagaagtt tgagatgtta
    13441 ccacgggctc cagagtccat catcataacg attgggttct taggatcttg gttagcaatc
    13501 aagcgtttct caagtttttc acgggcagca cgccattcag ctgtaacagc attgtaacgc
    13561 tcgtcgtctg tgatcatacc acgacggaat tgtttggtga tttgctcgac acgtttgtgt
    13621 gattcttcaa tgatttcagc cttgtcatca acgactggga tatcggcaat acccactgtc
    13681 aatcctgcaa gagttgagtg gtggtaaccg agattcttca tgcggtcaag tagggcagaa
    13741 gtttctgtcg tacggaaacg tttgaagatt tcagcgatga tatttccgag gtttttcttc
    13801 ttgaacggag ggttgagctc aagattgctg atagcttcct tgatatctcc accaagtggc
    13861 aagaagtatt tagctggaac accttctgtc aagttggcat tgtttggttc ttgcaagtat
    13921 ggtagcccct ctggcatgat atcgttgaag agaattttac caactgttgt aagcaagacc
    13981 ttatgtcttt gctcttctgt ccaaggcttg ttgaggctgt ctgttgcgat accaacacgt
    14041 gagtggaggt gaacataacc attgcggtaa gccataaccg cttcgtcacg gtctttgaag
    14101 accattcctt caccttcgcg accagcttct tccatggtca agtagtagtt acccaaaacc
    14161 atgtcctgag atggagtaac taccggtttc ccatctttcg gattcaagat gtgctcagca
    14221 gctagcatga ggatacgagc ttctgcttgt gcttcttctg aaagtggtac gtggatggcc
    14281 atttggtccc cgtcaaagtc agcattgtag gcttcacaga caagtgggtg caagcgaaga
    14341 gccttaccat caatcaagac tggctcgaag gcttggatac ccaaacggtg aagggtcggt
    14401 gcgcggttca aaagcactgg gtgttcttta atcacttctt caaggatatc ccagatacgc
    14461 tcatctccgc gttccaccaa gcgtttagct gctttgacgt tttgcacgat atcacgggca
    14521 acgatttcac gcatgacaaa tggtttaaag agttcaatcg ccatttcacg tggcacacca
    14581 cattggtaca tcttaagagt tggaccaacg gcgataacgg aacgtcctga gaagtcaaca
    14641 cgtttaccga gcaagttttg acggaagcgt ccttgtttac ctttaagcat gtggctcaat
    14701 gatttcaatg gacggctacc tggtcctgtg attggacgac cacgacgacc attgtcaatc
    14761 aaagcgtcaa ctgcttcttg aagcatacgc ttctcatttt gaacgatgat acctggtgca
    14821 tttaactcaa gcaaacgagc caaacggttg ttacggttga taacacggcg gtaaaggtca
    14881 ttcaagtcag atgaggcaaa acggccacca tccaactgca acattggacg aagatctggt
    14941 gggataaccg gaagaatgtt aagaatcatc cattcaggtt tgtttccaga cttgtaaaag
    15001 gcatccaaaa catccaaacg acggatggct ttgacacgtt tttgtccagt agctgttttc
    15061 aattcttctt tgagttcagc aatttctttt tcaagatcta cttgcttcaa aaggtcttgg
    15121 atggcttccg cacccatctt ggcaacaaat gaaccataac catattcacg caagcgctct
    15181 cggtattcgc gctctgtcat gatagacttg tgctcaagtg gtgtatcctt aggatcaatc
    15241 accacataag ccgcaaagta gataacttcc tcgagggcac gagggctcat atcaagggtc
    15301 aagcccatac ggcttggaat ccccttgaag taccagatgt gagatacagg agctttcaat
    15361 tcgatatgtc ccatacgctc acgacgaact ttcgtacgcg ttacttcaac cccacagcgg
    15421 tcacaaacaa ttcctctgta acgaatgcgt ttgtacttac cacaagcaca ttcccagtct
    15481 tttgtaggac caaagatcac ttcatcaaag agtccttcac gttctggttt caaggtacga
    15541 taattgattg tttcaggttt tttgacttct ccataagacc atgaacggac tttacttgga
    15601 gaagctaggg tgatttgcat acttttaaaa cgatttacat caaccactat ttcttccctt
    15661 tctattctaa gtgaactgct tattcttgtt cagcagcttc ttctgttgct tccgcttttg
    15721 ttgctttctc agcttcttca gcttcaaagg ctgctttagc ctcttgagct gctttttcgc
    15781 gggctttttc aaggtcatct acgtggatga catcttcgtc cattccttca tccaagtcgc
    15841 gaagttccac ttcttggtca tcttcgtcta ggacacgcat gtcaagacca agagattgca
    15901 attctttgac aagaactcgg aaggattctg gaacacctgg ttttggaatt ggtttgcctt
    15961 ttgtaatagc ttcataggct ttcaaacgtc cgttgatatc gtccgacttg taagtcaaga
    16021 tttcttgaag gacatttgac gcaccgtagg cttcaagagc ccaaacctcc atctcaccga
    16081 aacgttgtcc accaaactga gctttacctc cgagtggttg ttgggtaaca gttgagtaag
    16141 gtccgactga acgcgcatgc aatttatcgt caaccatgtg gtggagtttg atcatgtaca
    16201 tgactccaac agaaacacgg ttatcaaatg gttcacctgt acgtccatcg taaaggattg
    16261 tcttggcatc gctatccata cctgcttctt taacagttga ccaaagatct tcagaacttg
    16321 ctccatcaaa gactggtgtc gcaatgtgaa taccaagagt acgagctgcc ataccaaggt
    16381 gaagctccat aacctgaccg atattcatac gtgatggcac cccaagtggg ttcaacatga
    16441 tgtcgactgg agttccgtct ggaaggtaag gcatgtcttc tacaggaacg atacgagaga
    16501 caaccccttt gtttccgtga cgtccggcca ttttatctcc gaccttaatc ttacgttttt
    16561 gagcgatgta aacacgaacc aacatgttaa cacctgattg caactcatct ccatttacac
    16621 gtgtaaagat cttaacatca cgaacgacac catcggcacc gtgtggtaca cgaagagaag
    16681 tatcacgcac ttcacgagac ttgtctccaa agatagcgtg caagagacgt tcttcagctg
    16741 aaagatcttt ctcaccctta ggtgttactt tacctacaag aatatcacct tctttaacct
    16801 cagcaccaat acggataatc cccatttcgt caaggtcttt gagggcatct tcaccaacgt
    16861 ttggaatttc gcgagtgatt tcttcaggcc caagctttgt atcgcgcgtt tctgattcgt
    16921 attcttcaag gtgaacagat gtgtagacat cgtccttcac caagcgttcg ctcatgataa
    16981 cggcatcctc gaagttgtaa ccttcccaag tcatgtaggc aacgattggg ttttgtccaa
    17041 gcgccatttc tccattttcc atagaaggtc cgtcagcgat gaaatcgcct ttttcaacga
    17101 catcaccaac ttttacgaga gtgcgttggt tgtaagcagt acctgagttt gaacgacgga
    17161 atttttggat gtggtaaaca tccaatgaac catcttcacg acgaacttct accttgtcag
    17221 catctgcgta agtaacttta ccatcatact gagcaatcac agccgcacca gaatcgtggg
    17281 ctgcttggta ttccatacca gtaccaacgt aaggtgcctg aggattaatc aatggcacag
    17341 cctgacgttg catattggct cccatgaggg cacggttgga gtcatcgttt tccaagaaag
    17401 gaatacatgc tgtcgcaacg gcaactacct gttttggtga aacgtccatg tagtcaacaa
    17461 tattagctgg atactcttgg ttgacccctt ggtgacgtcc catgacaatc ttctcagcaa
    17521 aggttccatc ttcattcaga ctagagttag cctgagctac agtatattca tcttcttcat
    17581 cagctgtcaa ccaaacaatt tcgttcgtga caacacctgt ttcacggtca accttacggt
    17641 atggtgtttg aacaaaacca tatttgttca agtgtccgta agatgacaag ttattgatca
    17701 aaccgatgtt aggtccttca ggtgtctcga ttggacacat acgaccatag tgagtgtagt
    17761 gcacgtcacg tacttcatat ccagcacggt cacgagtcaa accaccaggt cctaaggctg
    17821 acaaacggcg tttgtgagac aactcagaaa gcgggttgtg ttggtccatg aactgtgaca
    17881 actgtgatga accaaagaat tctttaactg cagctgttac aggacggata ttgataattt
    17941 gttgtggtgt caagacttca ttgtcctgaa cagacatacg ttcacggaca ttacgttcca
    18001 tacgagaaag tcccaaacgt acttggttgg caagcaattc accaaccgca cggatacgac
    18061 gatttccaag gtggtcgata tcatctacac ggccaagtcc ttcagccaag ttgaggaagt
    18121 agctcatctc agcaaggata tctgcaggag tcaccgtacg aaccttgtca tctgggttag
    18181 cattaccaat gatcgttacg acgcgatctg gatcagttgg agcaacaacc ttgaattttt
    18241 gaagaacaac aggctcagtc acaacggctg catcgtttgg gatgtagaca atcttgttca
    18301 agtcgccatc caaatggctt tcaatgcttt caatcacgct acgagtcata atcgtaccag
    18361 cttctaccaa gatttctcca gtttcagggt ctaccaatgg ctctgcaatg gtttggttga
    18421 gcaaacgtgt tttaacattg agttttttat tgattttgta acgaccaact gctgccaagt
    18481 catagcgacg tgggtcaaag aagcgagcca caagcaagct acgtgagctt tcagctgtct
    18541 taggctcacc tggacgaagg cgttcgtaaa tttctttcaa ggcttcgtct gtacgagagt
    18601 ccattggatt cttgtggata tctttttcaa cagtgttgcg aaccaattcg ctgtcaccaa
    18661 agatatcaaa gatttcatca tcacctgaga aaccaagagc acgaaccaag gttgtaaatg
    18721 gaatcttacg agtacggtcg atacgagtgt aggtgatatc ttttgagtcg ctttcaagtt
    18781 ccaaccaagc tccacggtta gggataacag ttgaaccata gcccacctta ccatttttgt
    18841 ctactttgtc gttaaagtaa acacctggtg agcggaccaa ctgagaaacg ataatacgtt
    18901 caccaccatt gatgatgaaa gtacccattt ctgtcatgat tgggaaatca ccaaagaaaa
    18961 cttcttgggt cttgatttcg cctgtttctt tattgatcaa gcggaaggtt acaaaaattg
    19021 gtgctgagta gctagcatcg tggatacgag cttcttctag cgtgtatttt ggttccttga
    19081 tttcatatcc aacaaattcc aactccattg tgtctgtgaa gtttgaaatt ggcaatacat
    19141 cttcaaacac ttccttaaga ccgtggtcta ggaaagcttt gaatgagtca gtttgaattt
    19201 caatcaaatt tggtaagtca agaacttctt tgattcttga aaaactacga cgggtacgat
    19261 gtttcccgta ttgaacgtca tgtcctgcca agatgattct cctttgtaaa taagttccaa
    19321 gccttgtcaa tcaggctttt ctaatcgcca tatggttgta aaccccttat caccgtgtcc
    19381 tcttgacgaa ttttcagaat ctttaagcct ctgttacaaa tgctcaaaat cttgaaaaaa
    19441 agcacaaaaa gagcagctaa atctgacttt ttcagaagat ttaactgctg tgagccttgt
    19501 ctggacaata tttcagacaa aacctacgac aaatgattac ccatattata ccctatttag
    19561 ctagattttt caaggggatt cagtaggttt ttggtaattt ttttcccata gaaaacttgg
    19621 catcacattc gaatcacgct atggtacaaa aaactgaaaa aactattgac tgaaaatcat
    19681 tttcaaggta taataataaa cgttaaggcg gtatagccaa gtggtaaggc acggctctgc
    19741 aaaagcttga tcgtcggttc aaatccgtct accgccttct ataacttgat ttatcaggtt
    19801 tcaaatgaac agaaagccca atttgaaggg ctttttttat tttccctcga ataaatacgt
    19861 ataactttaa aaacttttgg agcgagtttg tggcagagtt ctttccatgg cataattccc
    19921 ttttgaaatc aattgaaaaa agcttcgtca cgcctggtga caaaagcctc tagtttattc
    19981 tgtttcttct tctatttcga cttctgtgat ttggactttt accttggtaa cacgtccatt
    20041 cttcacttta tcattggtta agataaactg tttgttttgg ctgaccaatt catagctgag
    20101 tttctcagtc gttggaatgg ttcccactcc tgtcaaataa taaccagcga tagtatcaac
    20161 gtcatcactt tccagttcaa cattaaagta attattgaaa tcattgaggg tcatagttcc
    20221 ttgaacaatg taggtatcct cgccaatctg atgaacatct attgctgctt tgtccgtttc
    20281 atcatcaatt tcaccaacaa tttcctctaa gaggtcttcc aaagtcacca aaccagccat
    20341 accaccgtat tcatccagca agattgccat ttgtctttgg gtatttcgca gttcttttag
    20401 caagtcatcc acaaaaatag tttcaggtac aaaaagtgga tcttgtaaaa ttctcttcca
    20461 aacaatattg tcaaaaccgt ccacaaagcc tgccttaagg agactcttgg tgtgaatgat
    20521 tccaattaca ttgtccttat ccccatcata aaccgggata cgagaataat tttgttttaa
    20581 aatactttgg ataatggctt gactatcatc ctgaatatcc accataaagg catccgttcg
    20641 aggaaccata acctctcgtg ccatcagttc atcgagcgaa aagacacctt gtaacatctc
    20701 aatctcatca gcatccaatg tttcttcact atttgtcagc atataggcaa tttcatcacg
    20761 ggtcatcttt tcatccgcat catcgaatga cataggagtc aaatggctca agaaattggt
    20821 cgaagcagct aaaagccaaa caaaaggact gactagtttt ccgatcccaa tgataaccgg
    20881 cgctgtacga attgccaagg catcctttag attaagagcg attctcttag gatataattc
    20941 cccaaaaacg atggaaatat aggtcaaaaa tgccaaggat agaaaagttg ccacggcttg
    21001 tgctgtttcg ccattcccaa gccaagaggc aatcacacgt cctagagtat cagttaaact
    21061 cgcccctgat aagattgtaa tcagggtgat tcctacctga atggttgata aaaagtggtt
    21121 aggattttct agtaccttca gcaggcggat gtagcgtctg tctccttctt ccgccttttg
    21181 ttcaactcgg gcacgattaa gagaaaccat ggccatttct gtggctgaga aaaaggcatt
    21241 taataccgtc aagataaaca ataaaacaaa ttgtagcaac aaattctgac tacttgggtc
    21301 ttccatagtt cttctcctaa aatagtatct tatcctttat tatatcacaa aatttaatcc
    21361 aatacatatt atttttttct tagcgtaact tccatctctc tcccaaaact ggaagttagt
    21421 ctaagacgga tttccactga tttcacgcgt ttttctcata ctaaaagcta ggttgtggga
    21481 aactggaagt tagttttaga agttactatt ttttcttagt acctgttcta gccctgctta
    21541 aactagtaaa aagaactcct acatccataa gtgacatagg agtttaggct tatcttttac
    21601 tgagttacag ttacttctcc agttcggtaa tccagttgaa gtcccttttg aacattggga
    21661 actagaacat tgaattccaa ttctccatcc gaagacttgg cttcaatctg tgaagctgag
    21721 ggaactaaat cctcgtttga agcgtagtaa agggttacac ggtaacggac acgcttgttt
    21781 tggtccaagg ctttacgcac cttgctttca tagtagtttt gaccagtcga atactcggct
    21841 tgtgcctgat ttgcccaggc tgtctgaaca gcaatgtttt taggattgct tgttgaggca
    21901 tcaaaaccat ccaaaccacc gattaaggca tagcctaaca aatgacctct atcgactgca
    21961 tgggtataag agccctttag attcttgacc tgatgccaac ctggaggagt ccaagaagtt
    22021 gaaccattcc cagtttcttt acgattcttg tactgacgag tggccttaga caagagggca
    22081 ttagctacgg ttggaacagt ttccttaccc actgtctttg ttttattgtc agcgtagggc
    22141 ttacttgaaa ccttggcatc tagatttgtt ttattaccat tgacgataaa agcacctgag
    22201 ccattccact ccagactccc ctttatttga ctcttgactg cgtctgttaa gacactctct
    22261 gccaatgctt gactaggagc ttcaggcgct tgttttttct gactaagctt ggttttagga
    22321 ctattagctg tcgactgcat ctgcttgata taatagctcc ctgtagacaa aagcaataac
    22381 actagcagtc cgattagtgt ctgtcttgtt tttttgttca tatttctcct tatctttaga
    22441 aaaaggctgg ttctccagcc taatttcctg taaatttatg aatcaattcc tgccattttg
    22501 ctggagacag gatagcccat gaatcttgac ccttgcccaa gattccataa cctaccatta
    22561 aaccgattcc tagagccaga gtacctaaaa tcagtactat gatgactaaa agtaaacgct
    22621 tgactacgta gcttgatttc ttattcatct tcatcacttg cctcaatccg ctgaatctta
    22681 gcacctagct gcgccaactt ctcatggaaa ccgtagtaac ctctatccaa gtgaaccaat
    22741 ttaccgacca cagtttctcc ctgtgctacc aaacctgtca aaatcaaagc tgcactggca
    22801 cgaaggtcag ttgaaagaac ttctgctccc tgcaaaggct gtccaccaac aatacgagct
    22861 gtatcacgga taatctcaga atgcaagccc atgcggcgca tctcttctag gtgttggaaa
    22921 cgattttcaa aaactgtctc caccatggtt gattcgcctt ttgcaactgt catcaaggct
    22981 gtaaattgag cctgcatatc tgttggaaat cctgggtggg gcaaggtttt cacatgaaca
    23041 gcttttagat tttccagttg agaacgaaca cgaattcctt cgtcttcttc aattacttca
    23101 acacccattt caagtaactt ggcaatcaag ggacggttgt gctcccagac agcgtctcga
    23161 atcaagacat caccaccagt catggcagca gctaccataa aggttcctgc ttcgatacgg
    23221 tcctggacta cattgtgagt cgtaccatga agtttctcaa caccagtaat ggttatagtc
    23281 tctgtaccag cacctttgac cttggctccc atttcattaa ggagaatggc taagtcaaca
    23341 atctcaggct cacgcgcagc attctcaatc actgtcaccc catcagccag agtcgctgcc
    23401 atcatcaagt tctgcgttgc accaacactt ggaaagtcca tatagatatg agcaccatgc
    23461 aagcgttctg cctttgcttc gatgtaacca gctgtctgac taatcttaac ccccatagct
    23521 tccagacctt tcaaatgaag atcaatagga cggctaccaa tcgtacaacc acctggcatg
    23581 gataccttgg catgacccac acgggcaagg attggcccta atacaacgat ggaggcgcgc
    23641 atcttactga catacttgta aggggcttcc tcagtgatgt cgccagtagc atccaccttg
    23701 acaagatgag cttcctcatc aaagtcaacc ttggcattca aaccaccaac tacctgattc
    23761 ataataaaga catccgacaa aatcggaaca ttctgcaaga cggtctttcc ttcacttgct
    23821 agaatagtcg ctgccaacaa gggtaagact gcattttttg ctccctcgat cgtcacgctt
    23881 cctaccagac gattatcgcc accttgaacc acaattttat ccatactcgt ttcctttact
    23941 cttgatttta taataatcct ctaagcgctt cttgccacaa atgatacagg ctaataaaga
    24001 aagaactcag gatgtagcct atgacaatgc taaaaaaggc tactaataca cgaacttttc
    24061 ttgtattctc agctgtcact tttaaaacct tttcccatct aacaagatcc tttaaaaggt
    24121 aaaaactcac ataaataaag agcatatgac tacttagagt gaataataat tgaaccattt
    24181 gactattata ccatcttctc tgtttgtgcg ctagtttgga aacttcactc aaaaattagg
    24241 gattgttttt caagtaatca atcgcatctt gtagggtttt aacgggcacg attttcatat
    24301 ccgtcttgat tgttttagcc gcttctaggg ctgtttggta gttgtttttc gcgtccggat
    24361 gcgccttttg ttcttcttcg ctaacagggt tatcaggagc aaagaaaata gcagcacctg
    24421 ccctagccga agctacaacc ttcttatcaa tacctccaat gtctcccaca ttaccatcgc
    24481 ggtcaatggt acctgtaccg gcaacaatac gaccattacg aagatctggg tgagctattt
    24541 gagtatagat agctagacta aacatgagac cagcacttgg gccgccaata ccagctgttg
    24601 aaaagctaat tgggacattg ctgattacct ctgtacgatc aatcaagccg attccaatcc
    24661 cattttttcc attttccaag gtgataatct tcccttctgc agacttggtt tgcccatcct
    24721 cttcataggt gaccttgacg gaatccccta atttttgaga actgacgtaa tcaatcaagt
    24781 ctttggaact atcaaaggtc tgatcattga ctgctgtgac tgtatcagag atattgagaa
    24841 tccctttaaa ggttgaatta tccgtcacat tcaaaacata aactccaaag tacttgagtt
    24901 cgatatcctt accagctgtt tttagtcctt gatacttggc catattttgc gatgtttgca
    24961 tgtagaattg attgattcgc ataaattcaa catcggaaga accacctgta gtctcctgag
    25021 cactacgaat atctgtaaaa ggtgtcaacc aagcataaat catatgagct aaagtagcat
    25081 gttgaacacc aaccgtaacg aattgatagg caccagcttc cttatcttct gtgtcattta
    25141 ctttaaggac ttggcgaata tcttccgaac cacctggaac ctctatataa taaggcaagg
    25201 gcactacaaa tgccaagaaa gtcacaatca aggccgcaat gacgtataag ggccatctaa
    25261 tctttttttt catttcttat ttcctccaaa atactctcgg gaacatagca ggcaatatcc
    25321 tgaccaaact tcaaaagctc tctaacgcct gatgaactga tatagagatg ttcaggtcga
    25381 ctatgtaaat aaatagtctc tatatcagaa gacagctgat gattgtagta atcaaaactg
    25441 gcttcatatt gcaaatccga cgcattcctc aaaccacgca ctagacaagt agcacccaat
    25501 ctttttgcaa catcgaccac caattcatca tgagaagcca cgacttcaac attttccaaa
    25561 tgtcccaaag ccttttctag cccccgttta cgattttcaa gagggagaaa tccttgtttg
    25621 tggggattaa aaaaaatacc cacacaaagc ttatcaaaaa gtctgctcgc ccgttcaatg
    25681 atatccagat gcccatttgt catcggatca aatgagcctg tgaataagcc aatcttatct
    25741 gacatagact gtcaccttac taattccata aatcttttcc ttccagatac ccagacaggc
    25801 aatttcttct ggaagttcaa cggtcttatc cgtctcgcac acaaccataa catcttcaga
    25861 aaaaagctct ctctcagcca ttttttcaat atctgctacg atttgttcct tggcataggg
    25921 agggtctaag aaaacgaggt caaattcccc agatacctgt tccaatgccc tttctgcatc
    25981 cattttgagg agttgaaatt ttccaacttc cttggtcatc tggatatttt cagccacgat
    26041 ggtctgagcc ttacggtctc gctccaccaa aacagcactg gacatgccac gcgatactgc
    26101 ttcgatagat aaaccaccac tacctgcata aaggtccaag actcgtccca cttcaaagta
    26161 gggaccaatc atgttaaaaa tggctcccct aaccttatcc gaagtaggtc ttgttgtctt
    26221 gccttctagt gtcttgaggg gacgtccccc atagattcct gatacgattt tcatactgtt
    26281 tattatacca aattatagac aaaaagagaa agaaaaccga accttgcggt tcgattctct
    26341 acaaaatatt ttcgtaagta tcgcggactt cttgaggcca aacacttgtt tgcacttctc
    26401 cgatgtgtct cttgcgaagt aggaacatgg ccatacgaga ttgtccaatt cctccaccga
    26461 ttgtcaatgg gaataggcca ttcaacaaag acttgtgcca ttccaattct aagcggtctt
    26521 catcacctgt aatttccacc tgacgtctaa gagtttcttc atctacacga attcccatag
    26581 aagacaactc aaaggctcca cctaaagact cattccagac aagaatatca ccatttagac
    26641 ccttgtagcc attctcagac tcgcttgtcc agtcatcata gtctggtgca cgtccatcgt
    26701 gcggtttacc atctggcaac tcgccaccga taccaatcaa aaagacggct ccaaattctt
    26761 tacaaatcgc attttcacgt tctttaggtg tcaagtctgg gtagcgttct accaattctt
    26821 ctgtatggat aaaggtgatt tgttttggca agatagactc gatgtcatag cgggcttcaa
    26881 cagctagctc agtcaggcga atagccttat aaatcttctc aactgtttct tttagataaa
    26941 cgatgttacg cttaccattt gggataacct tctcccagtc ccactggtca acataaacag
    27001 agtgggttgc atccaaggaa tcctcatctg gacgaagggc tttcatgtgg acaaagagac
    27061 cctctccttc accaaagcca aaacgagcca aggtgtggcg tttccattta gcaagtgagt
    27121 gcaccacttc ataagtagca tcagggattt ggagaacctt gaccgatact ggattttcca
    27181 caccagacag gttgtcctgc attccgtcac cgaccttact caagatagga ccttgaactt
    27241 cgacaacttc tagcttatct ttcaaatact gggtaaaagt gtttttgaca aaggaaattt
    27301 cttcttgttg atggataaaa cttttcttca tagacaactc ctcaaaaatt taataaacgt
    27361 attatacacc tatttccaag aaaagaaaag agaaaatttt aaaaaaatca gtgtcactca
    27421 aaacactgat ttcatagacc ttttagtcat tgcgaccaaa gatacgtaga atacttagga
    27481 aaagattgat aaaatcaaga tagatgctga gagccattga caccacccag cctgtcgcta
    27541 cacgaccttg tgattgttca taggcgaggc gaatcttttg gttatcccaa gcaatcaacc
    27601 ctgaaaaaac caaaaccatg gctacgctaa tcatataatc aaagaagcca ctagccaaga
    27661 aaatattgac taccatagca atcagtaaac caatgagagc tgccatcatt gctcgaccaa
    27721 tcccactcaa gtctttcttg gtaaaaatac caactgccgc catgacaaag aagagaaggg
    27781 cgctcgatac aaaggcagat aaaactgtac ccggagtata gaaagccacc acaaaactaa
    27841 gggtaaagcc gtttaaaacg gagtaaagta aaaatactgg aagagcagct ggactatttc
    27901 ttgaagccat gctactggca acgaaaacca aagccaactc cgcaaaagta gcaatggtca
    27961 accagagacg cccctgcatc aacaagtaaa ccaactgaga ctgaaagacc gtcaacataa
    28021 ggcctgatac caaagcagat agtccgattc ccagaccaac aaaggcataa accttagcgt
    28081 aaaattgatt gagacctgca cggtcatgta taatagtgtg attcatcctt ttctcctttt
    28141 ctgtgaacat ctttccttga ttataacaaa aaaagttaaa attagcttaa atggaagatt
    28201 aaaataccgg ctgcaactgc aacattcaaa ctctcggcct gccccttcat gctaatatgg
    28261 accaactggt ctgcactttc agccataagg ggactaattc cttgaccctc atttcccata
    28321 actagtacaa aattttctat agaaggcagt tctctgtaat caacagaatc tttagatagg
    28381 gttgttgcta gcactgggat agctaccttt ttagtttcgt caagaagcgc ttgactagtc
    28441 atccggtaaa tgggcagatg gaaatgacta ccttgcatgg aacgtagggt tttgagactg
    28501 tagatgtctg ccgacttatc tgaaacaatc actcctgtaa aacctgctgc atccgcagtt
    28561 cgaatgatag ttcctacatt accaggatct tgcacatctt ccaaaaacaa gaacttgccc
    28621 tgactcaaat cagcttgtcc tacttcttct ttttgaacca cggcaacaat tccctgtgga
    28681 gtctgagaat ccgccaaatc tagcaaaata tcctctgaaa tccagacagt ttgcggaaaa
    28741 gcagctaact gatttcgata attttctagg gcaaagattt tctcaatcgt cactccagct
    28801 tggacagctt cttcaaacaa gtgccagcct tcaatcaaat aggcagactt gcggtatttt
    28861 ttttggtgta atttcttggc attttttacc acagaattgg cttttgaggt tataatagtc
    28921 atagaaatat tataacacaa tcaaaggggt ttggtatgca aaaggttaga atgattgccc
    28981 aaggtagggt gcagggagtc ggctttcgtt ggggtgttta tagcctggcc cttgaaatcg
    29041 gtggcatcac aggtcgggta tggaataacg acgatggcac agtggaaatc ttagcccaag
    29101 cagactcatc tgctatcatg gcaaaattta tccaagaaat ccgaaaagga ccgacacctt
    29161 tttcaaaagt aagctactta gatgtcaaac taagcaactt tcctccctac tctgacttta
    29221 aaatcgcaaa ttaggtctcc agaactattg tatattttgt aaaaaaacag tagaatagaa
    29281 aggtataatt tttaaagaag gaataaaaac agtgaaatct attaaacgtt ttgcattctc
    29341 ggctatggga gtggctatgt tgcttgtctt gactggctgt gtcaatgtcg ataaaaccac
    29401 aggtcagcca acaggattta tttggaatac gatcggagcg cctatggctg aagccatcaa
    29461 gtacttcgct actgataaag gtctaggctt tggtgtcgct atcattatcg taaccattat
    29521 cgtacgcttg attatcttac cacttggtat ctaccaatca tggaaggcaa cgcttcactc
    29581 tgaaaagatg aacgctctca agcatgtcct tgagccacac caaacacgtc tcaaagaagc
    29641 aactactcaa gaagaaaaac tcgaagccca acaagccctc tttgccgctc aaaaagagca
    29701 cggcatcagc atgtttggtg gtgtaggatg tttccctatc ctccttcaaa tgcctttctt
    29761 ctctgctatc tactttgctg cccaacatac tgaaggggtt gctcaagcaa gctacctagg
    29821 cattcctcta ggttctccaa gtatgatttt ggttgcctgt gctggtgtcc tttactatct
    29881 tcaatcgctc ctttcacttc acggagtaga agatgaaatg caaagagaac aaatcaagaa
    29941 aatgatttac atgagcccac tcatgatcgt cgtcttctcc ctcttctcac cagctagtgt
    30001 cacactttac tgggttgtcg gtggtttcat gatgattctc caacagttta tcgtcaacta
    30061 tatcgttcgt ccaaaacttc gcaaaaaagt ccgtgaagaa ctagccaaga acccaccaaa
    30121 agcaagtgct ttctctaaac caagtggacg aaaagacgtt acccctgaac aaccaactgc
    30181 tatcacaagc aagaaaaaac acaaaaatcg caacgctgga aaacaacgtt cgagataaga
    30241 agaaaaaggc ttagctgatt tgctaagtct ttttgcaaat caaaagcccg atgtttccat
    30301 caggcttctt ttctatccat gtacacgttt catataatct tgataacttt cggtatccat
    30361 gagtttttta gcgttcttga cgcgatctgc tgttggtggt ttgactcctt cgagggaata
    30421 tggaattcca agttcacgcc acttgaactc acccatggtg tgataaggta gaatttcaaa
    30481 cttatcaaca tttttgaggg tcttgacgaa cttaccaagt tcaatcaagt catcatctct
    30541 gtctgtcaat cctggaacta gcacgtggcg aatccagaca ggttttccaa tatctgatag
    30601 atactgggca caagccaaga tatttttatt agtttggcta gtgacaatct tgtgctgttc
    30661 ttcgttgatt tccttgatat ccaaaagaac caagtcagtg acagccatga gtttgtcaaa
    30721 cttctcaagg taacgtggtt tattacggaa aggaagagca caggtatcca aggtacagtg
    30781 gattccttgt tccttagcct tggtgaagag agcaatcagg aaatcaatct gcaagagagc
    30841 ttctcctcca ctgactgtaa tcccaccctt atttccccag aaaccacggt agcgcaaggc
    30901 ctctgtcaag acatcatcta ccgtccgttc acgtgactta ttggactcca tagcccaagt
    30961 gtctgggttg tggcaatact ggcaacgcat gtgacagccc tgcaaaaaga caataaagcg
    31021 aataccaggc ccatctactg acccaaagct ttctgtcgaa tgcaccattc ctgtcacttg
    31081 tccataatca attgtttctt cagacatatc gttaccttcc ttgaaaacgt tttatagttt
    31141 tattatatca cgacttgaag gaaaaacaag atttttgcct attttttaga aagcaatctg
    31201 tttttcaatt tcattttcaa tctattatca gattattctt caaaatcgaa gccatataag
    31261 gttgcaaaat agtcctcagg gcgctctgca cggcggattt gacgggcttt accttcttcg
    31321 gtatagagga tttccgcaga acgtaatttg gcattatact ggtagcccat tgaaaatccg
    31381 tgggcacctg tatcatgaat taccagcaaa tcaccgattt ctgtatgagg cagttcgcga
    31441 ttgactgcaa atttatcatt gttttcacag agtgaaccaa ccacatctac cgcttcagct
    31501 ggtccatctg gatgggtcac gttgctaata tgatggtaag ctccgtacat agctggacgc
    31561 atgaggttga ctgctgaggc atccacacct agataggtac ggtaggtttc cttcttatga
    31621 gtcactcttg tgactagagc accgtgaggt gccagcataa aacgacccaa ttcggtgaaa
    31681 atcttgacct gaccaagacc tgctgacgta agaacttctt catacacctt acgaactccc
    31741 tcaccaatca aggcgatatc gttcggctcc tggtctggac gataattaac accaataccg
    31801 ccagaaagat tgataaagtc tagcgaaatg cccaactttt ccttgatttc aacagccagt
    31861 tcaaagagct gacgagccaa ctctggataa tagagatggg tcacggtatt ggacgctagg
    31921 aaggagtgaa tcccaaaagt cttggctcct ttttccttca agatagcaaa ggcttcaaag
    31981 agctggtcct tggtcatgcc aaacttagcc tccccaggat tgtccataat gtctgtcccc
    32041 agttcaaaaa cgcctccagg attataacga caagagatga tttctggaat gcctgctact
    32101 ctctccagat gttcaatatc ttcaaaggca tccaagttaa tggtcgcacc caattcacgt
    32161 gcataggcgt attccttgtc tggcgtgttg ttggaagaga acataatctc agaacccaga
    32221 aagtccagtt tatggctcat caaaagctct acataactag agcagtccac accacaacct
    32281 tcttcttgga gaattttcaa aatagctgga gttggagtag ccttaactgc aaaatattcc
    32341 ttaaagccct tgttccacga aaaagcttgg ttgacggctc ttgccttctc acgaatcccc
    32401 ttctcatcat acaagtgaaa gggagtcggg aactcggcaa caatcgcttc taactcttct
    32461 ctattgataa atggtgtttt cataagcttc cttctattct gtttgcaaag aaaggctggg
    32521 acaatcgttc caacctttag ttctatctct tatttatctt cgtcaaagat attgccaacc
    32581 tcaacatcga tggcttggtt cttgacatca atattggtta ccttcaagag tgacttgtag
    32641 tcaaactgct tttcacgttc ttcttgggca ttgtccgcaa agaccgctac acctgccagt
    32701 tctgagtcga actcgtgcaa gagactaatc ataccattga ccgttccgcc acctttcaag
    32761 aagtcatcca caatcaagac acggctgcct gccttaagac tacgttttga aaggaacatt
    32821 ttctcgatac ggtcaccact tgaacctgaa acatagttga cgctaacagt tgaaccttcg
    32881 gtaattttca ggtcacggcg cacaatgaca aaagagacat tgaggacatt ggcaactgca
    32941 tttgcaagtg gcacaccctt agttgctacg gtcataaccg cgtcaatttt ttggtccata
    33001 aagcttttgg caataatacg accaatattt ttcaagatgg ctggtgtgct aagcaaatca
    33061 gacagataga tataaccacc tggcaagata cggtcacttt ctgacaactt ggtacgcaag
    33121 tcttcaacca tttccttagc atcctgactc gaaatagacg gtgtgaagat gacacctccg
    33181 ccagccccag tcactgtctg gatatgaccg atttcaattt cctcaaaggc gcgtttgata
    33241 atgacgatat cttctgagat ggatgattta gcagactcat acttttcagc aaaagtattg
    33301 agactagtta gtttataagg attattaatc aaatagttgg aaatgacaac catccgatca
    33361 cttcttctta atttcatttc tatttcctat tccattttta ttcaaaaaat caaaaagcaa
    33421 actagaaagc tggtcgctgg tggttcaaaa cactgttttg agattgtcaa tagaactgac
    33481 aaaccctgta atatacctgc atatatacat acgacaaggc gatactaccc tagtttgaag
    33541 agattttcga agagtattca tttttgtctt ttacttatta taccatattc acataaaaaa
    33601 acgaacattc ttatcctaaa aaatgctcat ttttcttaaa ttatcaatct aaatctggtt
    33661 tatagaagga acgattatcc atagcgaaga ttttattggt catctctcct ttatccacca
    33721 aagccagagc tgttgacatc atcatcatgc ttgcatccag attgtcaatc atatggataa
    33781 tctctgcctc cataatacgt ggacggactg gacttccata ttcaagcaag ccgtggtgac
    33841 tgaggatgac atgacgaagc aaaacgactt cttccttggt atcatcgatg ccgagttcca
    33901 taactgtctt ggtaatttcg ctatcaatga gagcgatatg tccaagaaga ttacctcgca
    33961 ctgtgtactc tgtctggtct ggccccgtca actcgataac cttagctaag tcatgcagca
    34021 taatccccgc atagagcagg ctcttattga gctgaggata aacttcgcta atagcgtctg
    34081 ccaaacgtac catggtcgcc gtatgataag ccaaccccgt ttcaaaggca tggtggttgg
    34141 tcttggcagc tggataggag tagaattcct tatcatactt ggtgtagaga tttcggacaa
    34201 tccgttgcca gacaggattt tcaattttga aaatcatttg cgacatgtag tcacgaattt
    34261 ccttgacatc aactggtgac ttgaccttga aatcggctgg gtcattgggt tcaccagctt
    34321 gaggcaggcg gagagtaatt tgattgactt gaggggtatt gttataaact tctcggcgtc
    34381 ctttcatgtg gacaacctta cctgcggtaa aggcctcaat gttatgaggt tgggcatccc
    34441 agagcttccc atcaatctcg ccactatcat cttggaaggt aaaggctagg tagtttttcc
    34501 cagctcgagt ttgcctcagg tcagctgatt tgattaggta aaagccttca aatagctcat
    34561 cttttttcat gtgactaatc ttcatattct tcctcatttt cttgaaaatg gagtagatca
    34621 agcgcaggct caccttctga caactcaatg tgacggagcg tccgctcgat agctatggta
    34681 cgacggttta ataattcatc aatattgcca gaggcatgtt ggagatgttt ttgtgccttg
    34741 accagaatac caccaaactt gccaaactcg gtcttgacac tggcaagagt cttgctgata
    34801 tggtcggcac tcttttggat attaagggtc ttgaaaccaa ctgatagaga gttaagaagg
    34861 gctgataggg tacttggtcc tgcaacaata atctgttctt cccgtctcaa atcatcaaag
    34921 aagaccggat tgcgcacaat ctctgaataa agaccttctg tcggaacaaa caagattcca
    34981 aagttggttg tccgaggtgg tgctatgtac ttgttcctaa tatccctagc aaagcgcttg
    35041 acgcttgcta ggagtgactt acgacagcgt tcaatctcat ccttgtcacc tgtctcatag
    35101 gcttcttcca agcggtaata atctgccagt ggaaacttag agtcaattgg cagatagacg
    35161 tattcttggt cgccttgtcc gggtaacttg atggcatact ccactcgttc actagagttt
    35221 tcaaccgttg cgtattctcg ttcgtactgg gcaggtgtca tgatgtcttc aataatttgc
    35281 cccagttgca attctcccag aatccctcgc gtcttggttc cagagagaac cttgttaaga
    35341 gctccgacat cacgggcaac tgtctgcatt tctccaaggc cacgattgac agactccagt
    35401 tgtttagaaa ctgtctcaaa ggaagcctgt aagcgtgtct gcaaggtctt ttctagtttt
    35461 tcctcgaccg tctggcgcat ttgttccaaa cgttgctcat ttgattcctg caaggcttgg
    35521 agacgttggt ctgtcttgtc tctagtttgg aggagattat ctgtcatttc ttgacggact
    35581 tgggtcagac cttggtgcaa ttcaatccgc acttcttgca aacggtcgct gacaaccact
    35641 tccaaatctt tttggtctaa ctggctggct tgtctggctt ggtcaaagcg gtaatccaac
    35701 tggtctgaca aatgatctgc ctgatcctcc aagctcttac ttaagtgttt ctcctgccta
    35761 tcctgccttt gccaaatcag aaagagacca gctagattgg caattaataa tagaataagt
    35821 aaactttcca tcctacctcc tgtccttgct atgcagtacg accacataac catctgggca
    35881 agttaccgac acttccctat ctatatattc gttagaagcg tacacttttt taaagaaaaa
    35941 attttcctct gtcaactcat acttggctcc aagaatagtc agctggctat cccgaactgg
    36001 cataaaggct agatagtcgt agtctgaacg aggttctagc tgactgattc cttctggaca
    36061 ataagtaatc aagttttgcc catcctcaat ttctatttga tgcatatagg atgccaactt
    36121 aggattgcta ggcagaaaga cattggccaa catatggtca atacggccac ccaaggcacc
    36181 gaaaatagta acctgagcct gaggattttg cttaaagatg gtcaagagag ccaattccaa
    36241 atcagtatca tctttttctg gccgggcttg gacaaaatac tgggcacgtt tttgaatcac
    36301 ctgtcgctct tcttccgtca cagaatcaaa atctccgact gctagagcaa gaggcaaatc
    36361 ttcttccaag atccagagcg agcctcgatc cacaccaaca aaaccatcaa agtccgtccg
    36421 ataatgaccg cggtctccgc ctgcaaaaac ggcaacccta gtccagttgt tttctgagag
    36481 tttgtactcg ctcattgaca tctcccttaa agacatagga acctgctaca aaaacggtcg
    36541 caccagcttc tttggcttga gcaatagttt ggtcatcaat cccaccatcc acttcaatct
    36601 caaagttcaa acctttttca tcacgaaggg caaccagctc acgaacctta tccatggttt
    36661 ctggcagaaa ggcttgacca ccaaatccag ggttaactgt catgactagg acttggtcaa
    36721 ctagatgaag cacatgctta atcgcttcaa ctggtgtacc aggattgata acaactgatg
    36781 gcttgacacc gagtgaacga atcttttgga gggcaccatg aatatgaggc gttgcttcca
    36841 catggatact aataatatcc gcacctgcac gcacaaagtc ctctaaatga tgctcagggt
    36901 ttgacaccat caagtggcag tcgaaaacca tcttactatg aggacgaaga gcttcgacca
    36961 cacccgcacc aaaactgatt tgcggcacaa aatgaccatc cataatatcg atatgggcat
    37021 actctgcccc agttgcttct aggcgtttaa tttcacgttc aaagttggca taatctgctg
    37081 ccagaattga cggagcaatc ttgtattgag acataggttt ctccttattt tggaattttt
    37141 ttgctgactt ttttataggt ttctctgcga ttttcaattt cgctgaggaa ttgcaggtag
    37201 ttgtcaaaac ggaagggcgc aatggtacct tcttcaactg ctggcttgac agcacaggac
    37261 ggctcatggg tatgggtaca agtacggaat ttgcagtctc gactgacagt ggcaatctct
    37321 ggaaaggcct gattgaggtc ttcagccgtt gatacttcat aatccagtga tgaaaagcct
    37381 ggtgtgtctg cgattttacc cccattgagg ttgtaaaaac taacagctcg agtggtatga
    37441 cgcccgcgac ccagactgtc tgaaatttct cccgtttcaa gattaagatc tggtgcgatt
    37501 ttattgagaa gagttgattt cccaacaccc gtctgcccca taaagaccgt aaccttgcct
    37561 gttaacaaag gcaggagttc ctctttactg gtcacaaagt catatccgat gtcaccatag
    37621 gtctgctggt aaaaatccag ttctcccccg tcttccaaca aatccatttt agaaatatag
    37681 acgatgggat gaataccctt atgctccaaa agaaccaaga aacgatccag caaattgctg
    37741 ttaaaatcag gttccttgac agacatgatt actacagctt ggtcgatatt gacaataggc
    37801 ggacggacca gactgttttt ccgttcgtga atcttgagaa tatagccttc tgaattttcc
    37861 tcggcagaga aatctaccca gtccccaacg taaggggtat gccctttttt acggaaattc
    37921 ccacgcgcgc gtgtttgata gacttggcca tcactctcta catagtagaa cccagccaag
    37981 gctttaatga tttgtccctg caaaataact cctttaaaat tgttagttcc attataacaa
    38041 aaaaaagcta ttttagctta gcttctcttt acaatttcga taagtctatt ctaaaagaaa
    38101 aagatacact cacgctttag ataccaagtt ttatacaaaa ataacgaatc tacctcctta
    38161 tataaaaaca ggcgaacaga gagcctaaaa ctccctgttc gctttacttt ttctgtgtgt
    38221 aatagaaaaa acctaataaa gcaagacaaa aaatatgaat ataaactcca tacatcatgt
    38281 ggggaaagac agactctata aaatagcctg gtagatagat gattggaaat tgatagaaat
    38341 cataggtcgt tagagatagt aaacaaagaa catacataaa tactgctaca attagaaccc
    38401 atccttgctt tcgccataga aaaatcatca ataagaacag acaaagtaga tagattgacc
    38461 aatttcgcaa cataaattga aaaccataaa tcatactttc agtcgtttct ccatcaatca
    38521 catcaactac tttatagaaa ggtaaacaat agctcactaa aaaaagaagg ggactaatta
    38581 tttttttcat attctctacc atggattatt ttgcaagtaa gctgaccatc tatctccata
    38641 tcgaatcaaa ttaacagtat aattagttac tacccgattt tcacctggtc caaccttaga
    38701 aaaacctgtg ctatactccc aactacttct tgcacctgga tgaaaccatt tttgctggga
    38761 tgaataccaa ccaccttgtc taacttccac acttgaagat tctatttcga tatccctttc
    38821 atggaagtca actcctccac ttattttagt aatatttttt tgtacacctc catcataact
    38881 cacccagtga acaacagtat acaattccac actataagta ctatcaaact gactttgatg
    38941 agtagtaatg ttttgagtat aagcgtgcac tttctgtata ccaaaaatat ggtctaatat
    39001 attcgttggt ttagcaagct tattgtaacc ctcttcaaca aaagtagcct tctctaaatc
    39061 agcggtataa acagtttttc cttgtactac ttgattgttt atagaagtaa tacggctatc
    39121 cacaacaatg ggggccacca tatctccatc gctagtttct attttagctg cctctttcac
    39181 ctcatataca actcgatttt cttcagactg aatcacttct accccatttt tttcaggtat
    39241 agataatcta gtttgcccat tagaaaccgt tatatttgga ccaatattct tctcatttgc
    39301 ataagtcgca ataggaaatc ctgatagaac cactgcacac ataaggctat tgactaattt
    39361 ttttctcatg aatatatcct tcccattttc aagaggagta aaaatagcta atataagatg
    39421 aacgtttcct tatatttcag aataggatat ctatctgaaa gcaattcaca ctcctataga
    39481 taactgttcc aaatcttggc tacatatatt tcaatagttt gctacaaaaa actcctttct
    39541 aagtctattg aacatgccct tattcaccta ctaatatatc acaaaaataa ataaatacaa
    39601 gactgttttt tctactagtt ttatgataga atagtattgt tagggtaaat ttcatatata
    39661 aatgtcgagt gaaaaatcga tggagcagaa atcggtagac aaagactcga tttcgttggt
    39721 ccagccccac aaggctaatc aggtatttca cgagtttaaa aatctaatga agtgcccaat
    39781 caactactga ttcattgatt taatacgaac tatagtggat tgaacctaga aatagtacac
    39841 taaggattct aaaacgtttc tagaaattaa tttgactttc ctaatctctt tgttcatatc
    39901 ttatttcaat ctactatata taccaaaatg ctaggacaaa agtctttaaa atcagagaaa
    39961 cgcatattat caggtgttgg aaaaccttga taatatgcgt tttatcatag aaagatctac
    40021 ttcatttttt actaaaatta agtttttgtc cctgcatctt agagtccttg ccctttaagt
    40081 gcatctgcta ggctggcaaa ctcttccaag ctgagagctt ccccacgcac acttggtgac
    40141 aagcctgctt ggtccaaagc cttggtcagc ttgtccttga cctcttcagt cttgccaaag
    40201 taacctgtca agttattcca caaggtcttg cggcgatggg taaaactagc cttggaaacc
    40261 ttaaagaaaa agttctcgtc ttccactgct acagctggca ctggacggcg caccattttc
    40321 aagatggctg agtctacatt tggtgctggc acaaagactg tacgcggcac gataaaggca
    40381 accttggctg tcatgtaata ctgcacagcg atagacaagc taccgtaagc cttggtattt
    40441 ggttgagccg agatacggtc cgccacttct ttttgcatca tgaccacaaa ctcactaaaa
    40501 ggaatgccac tctcgattaa gtgcatgaga ataggcgttg tgatgtagta aggcaaatta
    40561 gccactacct tgattggcag gtcaggattt ttgaaattct ggatatgttg cgccaaatcg
    40621 accttgagaa tgtcctcgtt gactacagtc acattgtcaa aatcacgcaa ggtatctgcc
    40681 aaaatcggta ccaaacgatg gtcgatctca aaggccataa cttctgctgc acgctcagcc
    40741 aaaaactcgg tcaaggcacc aatacctggc ccgatttcaa tgacattgac ctggtcatca
    40801 atctcagccg tatccacgat tttttgtagg atattggtat ccgtcaagaa attttgccca
    40861 aaggactttt taaaggtaaa accgtgacgc tccagcactg ccttggtcac gctataatct
    40921 gcaattctca tctattctct tttctattat ctgttactac tattgtaaca cattcccctt
    40981 gtattttggg ggtgaaaatc ataccaaaaa actatctttc ctcatgaaga aagatagtct
    41041 tggaaatctt taaaagtggc cttagcgctt ctctcgaaac atacgttcat actcttcgaa
    41101 aatctcttca aaccacgtca gcttcacctt gccgtactca agtacagcct gcggctagct
    41161 tcctagtttg ctctttgatt ttcattgagt atcaaaaaaa tcagcttctt gataacttcg
    41221 attttcgggt agggtcaaat ccacatcctc ctccacatca tccactgtca gttcaaccgt
    41281 ttgaggtaaa tttttcaaac gataatgctt ttgcctttgc ccttcactac tagcaaaatc
    41341 aagcaaatag ccatgcactc ggatttgaac caaaaggaga ggattggtca tattttccat
    41401 gatgaggata tcttataaac cacctctggc actaggataa tcagataccc tgcgaatacg
    41461 gattttttca cacatgagca agtttcctca tatcaatgat ttcatcagcc ttattccaga
    41521 ctaggggatt atgggtcgca atgatgataa ttcgattttc atctttcaaa tccaccaaga
    41581 gattcataac ctcctctgaa ttttcaggat caagagctgc tgttggttca tctgccaaaa
    41641 tcaagggtgg atttttcaaa atagttttcg caagggcaac tcgttgggcc tctcccccag
    41701 ataaagtata aattttttgt tctaaatcca aataccctag attaactttt tctaaagccc
    41761 ccacttgcct ttccaaacgt tctacttttg agattttctg accaacaaaa cccaaatcca
    41821 aattttcttt gattgattgg ttttctaaga ggccaaaatt ttgaaagaga tagcccatct
    41881 gatctcgaaa atactcacga gtgggaatgg tttttaaatc tttcccctga tagagaaccc
    41941 ttcctccatc tatcttttct agctttccca agatattcag cagcgtcgtc tttccgcttc
    42001 cactctttcc gattaaggca taaaccttgc ccttctccag cttgagattc aaaccagaga
    42061 aaatcgcgcg gtcattaaat ttcttttcca atccttgaat atcaatcatc ttattttcct
    42121 ttcaatactg ccatgctacc agcttcttct tttttgtcct gccttactaa aatcaagagg
    42181 gcgttaagcg taaacaaagc tacaactaga gcgctaatca aaccatctct tgtcaaaata
    42241 ctagatagga ctaggccaag caagagaact cctccttgcg ccagtaaata cttgccatga
    42301 agctcataga ttgtcatacc agcaagacgt ttaatcataa gctcccgtct gaactgctca
    42361 aaatagagaa gattcatgga atcaaataac aagatagccg tagacagggt caaaatcgtc
    42421 ccaataagga gagagtaaaa ctctacccgt ttgtcattta gtaccttggc aaaaaatagc
    42481 tggcttttta ccaagtaaga aaccttgtga tacagacctt gctcttttag agctgtgatg
    42541 ctgtctccat atcgatctag tttcaaggca ctattagccg tagttcccca caacatccct
    42601 gcaacaggtc ttgttccagt cgcttgcggc gttagaacta caataatcgg atcttttagg
    42661 tactggcgtg ttgtcttgta cccatcatta tagaggaaac gttcctgtcc tgtttctgta
    42721 aaagctagac ttacctgtgg gaggtagtat ttctgactcg tcacttctac actttcagat
    42781 gaaaagtttt gcaggtaatc tgtaaacaat ctttggtagt aggtagactg ctctcgcaag
    42841 ctctcaggca agattagccc aaactctccc tcagacaagt tttgcatctt gtccataaac
    42901 tctgaagaaa cggtaatctt ttcttctatc agatagcgtg gtgagacata gataacattc
    42961 cctgacggtg tgtagtcact gagacgattg ccatctaggt ccacttctgc tccgtctgag
    43021 aaattgtcaa cattgctcat aatataaaaa gagtctgtat tggctaaccg ttcttcagta
    43081 aatgtctgcc actcacgatt atccttacgc gttccttctt catcggcaaa tgcactagac
    43141 caaccaaagg atagacggta acggtctgag gactggctcc atttattgct agctctctcc
    43201 atttcctgca tttcacggta gtggggtagg agagctgtcg cactcgatcc gaccaccaat
    43261 acagctaaga gttgccccac catcatcaat gtcatcatac gtttgagagg gagtttccct
    43321 ttcaatagat ccaccagact attttcctgt aaaccaagta gatagacgac acttagtaag
    43381 gtagaaatcc ctgccagggt caatccataa agtagaagag caatgatgac cagttgcacc
    43441 gttgccataa acaaggcacc ttgataccag agaatcccca atcccaaaag actggatacc
    43501 agcactgagc agataaactg tctcacatct tctaacactg gtctgagagc aactccaaac
    43561 aagctctcac cagctattaa gcgaatccct gcctgacgaa gggatttgat ccgataaatc
    43621 agggtcagac tcataaaggt cagcagaaaa atagctaaac tcagtagcac cataggggtg
    43681 gccgccaata gtaagactat cgaaaatgga tcttctccat tcgaaacaaa gccttgatag
    43741 ccaagttctt tcaaggtggt ctgtaagctc actccatcca aacttcctga cacaatcaag
    43801 taagacccta ataaatcact cgtttctgca ctctccttgg aggaaatggt cagaccttct
    43861 ggaagctctc cctcaccata agtggcatag gtaaagagtg tttctccagc ttcatttggc
    43921 tcaacgattc gacgggcgat gagactatta tgctctaccg ccaagtgact caaaacctct
    43981 gtcacctctt cgcgactagc tactggttga tttatcatca ttcctgtcac atcaacagaa
    44041 ggatagttac caaataaaat ctcttctcga tggtcaacgg aagttatcac catataaagc
    44101 gataccaata ccattgaaat caaaataaat aaacgtttca tcatttcctc caaaaagtta
    44161 cttggtcact tagtgagaag gtgaccacag tcactgcgat gttaagaagc ttattaagtt
    44221 ctttctacta gcaacatctt caaatacatt atatccgttt tttcaagaac tatcaaggac
    44281 atcaatgtcc ttaaaatcta actatttcat attattttta gcttatatct aaaaaaacag
    44341 ttctaaagac gaactttaga actgttttga tacgaggaca aggacatttt tgtcactgat
    44401 tcactatgtt tataaatatt ttttgacatc ctcttgccat tcctctgtca atttctttac
    44461 tagaaatcca tctccaatta gcttcgcaaa tgttttagaa gactgataaa atgattcagc
    44521 taaactaaaa tctctttctt ctcttaatgc ttgcttccac aaaaacataa atacaagagg
    44581 tttcttttga taatcttgag ttttatccat aatttcttgt aaacacgata gataatcatt
    44641 aaaacaatca gttactccta ccttttcaag acaacacatt cctgaaataa gagtatctct
    44701 aattataaag aagttttcta atttagttac ctttttctgt tccaaaagaa agagcattag
    44761 cttttcgatt tgatttataa atttggcaag atcttttcta atgagcattt gataaaaaaa
    44821 caaacgaatc aacaacatat catttgttga ataaacttct ttttctatga tctgagacat
    44881 atgttcctca agtattaact ctgcatattc aggccttcta gttctagaag tatccaaaca
    44941 cgcctgcaat acttcacatg ctaattgttc ttctttagga agattatcaa agtatgtttt
    45001 ataaatctct tccaaacacg cttccttctt atcgtactcc tcttctttac catagattgg
    45061 ttcacgtaaa atctggtatt tcaattctaa ataagcagga ggaagagctg aaaaatccgg
    45121 cataaggcta taaactggaa ctcctagccg gcgagcaata taggctaact tgggcaaact
    45181 cggttgcgaa gctccacttt caattcgcga cagttgacga actgtcagtt cttgctcatc
    45241 tccacaaaaa tatggacgac taactccttt ttctatccga atctctttaa ttttttgacc
    45301 aattaacatc agacgcctcc tcttctacct gcttcgaaaa atactgtgaa acttaaaaaa
    45361 ttgtaacggc tacatctttc ctactcataa gatttcatag cttcttccac ttctgccaaa
    45421 gtaaccccaa acaactctag gcgtttgagg agttgcttgc cgttagaata gccgattcgg
    45481 agagtctctc cgagatattc tctacgctta cggctgtctg cccctgctag aaaaccaagg
    45541 cgaatcaagt cgctacgact aatgtcaaac tgactctcat gttcaaattg ttctgtcacc
    45601 tgagctagag ccgttttcag gtcttcatag ctggcatgct caattcccag agaacgcccc
    45661 ttggtcttgg actttggaac agcttcatct cgcttgagaa aggcatgccg aactgttgga
    45721 atggccgtca taatcatgcg ccgaatccgc tccccattaa aatctgggtc tgtaaagaca
    45781 atgactccat gacgttggtg caggcgctga atccgctcta tatcctgagc attgatggca
    45841 gaacctcgag tctcataggt ctccacatcg aaataacgtt tgagattgac cgtatcatca
    45901 cgcccttcaa ccacgataac ttgagaaatt ttctctttca ttacttgctg tccaatccaa
    45961 aaatgcgttc tgcatttgca gtcgttgcta ccgccagctc ttctgtcgtc ataccacgca
    46021 agtcagcgat aaagtcgacc acatagcgag tataggctgt tttattttca cgaccacgct
    46081 tgggtacagg tgctaagtaa ggcgcatctg tttccaccaa aatcttgtcc aaaggtaact
    46141 ctttagctgc ttcttggagg tcagttacct tcttaaaagt caccactcct gagaaggaaa
    46201 tggtcatacc aagatccaca aacttctctg cccactcaag cgtccctgaa aatgaatgca
    46261 tgataccacc acgaggacca acgccctcac tcttgataat ctcataggta tcttccagcg
    46321 catcacgggt atggacaaca aaaggcaaat ccaagtcctt agatagctga atctgacggc
    46381 gaaaaacctg ctcctgcacc tctttgggcg ctgtcatcca atggtaatct aagccaattt
    46441 cacctaaagc cacaaccttg ggatgtttta acttatccaa caagtaagcc tcaacttcct
    46501 ctgtataagt accagcttct gtaggatgcc aaccaatagt cgcatagagc tgatcatact
    46561 catctaccaa ctccaaggca cgctcaatcg tcggtttatc aaaaccaaca atattcatct
    46621 gtgtcacacc catctcagca gccaaggcaa tttcttctgc ctcacgacct gcaaattctt
    46681 ctacattcaa gtgtgtatgt gtatcaaaaa tcatctcttc taacctcgtt ttctatcttc
    46741 tattatacca aaaaagagga ggggcaccta atttttcggt ttcccctcct ctcttcaata
    46801 gagagctatt ctgctatctt ttctatccga tattgcccat ctcctattcc acagttagag
    46861 acagaagaga ttggctacat tgatagaata ttcctattca gctaaagtat gtgattatct
    46921 tgggttctca cttttctcac ccatcactag gattgatgac ttctcaaaat cccccttata
    46981 atctaacttt aagtagagaa tagaattttc tagctgttct attttctacg tctagtcttt
    47041 cttcctagca aagcaaaacc acttgttgcc accactagac caagactagc aagtgctgca
    47101 cttgatgctg aacctgtgtt aggtaattgt ttgccagcag gtgactggta ggtaacatct
    47161 tgcattgttc ctgcagttgc ttgcggtgca cttgttgtct taggagcagc attaggagcc
    47221 actggtctct taggaactgt aaccatgaca atggcttgca ctccaatcgt ttctgcttcc
    47281 ttcacatctt ccatagtttt cgcattttca atctctttga gagctgcttg tttttctgct
    47341 tccactcttg ctaaaagttc tgctttttct ttatcagaaa gcggtgcgcc tttgatttca
    47401 tcctgcttgt ccttggctgc tttttcaatg gcatttttag ctgattcttt ttcagtagct
    47461 aattgcttag aagcttgtga ttgagctgag ttttgtgaac ctgtgtgagc tgatccaccc
    47521 gcctggctac caccgcctgc attcgcatta gcatctgagc ttccagtatt gcctccctta
    47581 tctccacctg gtgtattttc tagcttatac tctggtgtag cttcttgagt tacagattca
    47641 cctttcgcag attgttgaac tgtatctttt cctagaatcg tcactactga accatctggg
    47701 aatgtgattg ttgctgtacc atctccagct acattgattg tcgctccgtc taatgctgaa
    47761 ccatttgctt gtaaaatagc aaccttaact ttttcttcat ctgttaaatg agttatatct
    47821 tttacatcta ctctttgagc aggtgcttta acagttgatt tttcagcagt cggtttagtg
    47881 ctatcttgtg cttttggatc ttgtgctacc aattgatttc ctggaattgt aatagctgaa
    47941 ccatctttaa agacgattgt cgctgcgcca tctccagcta cttcaacttt atagtaaaat
    48001 gaaataataa caggacaaat cgatcaggac agtcaaatcg atttctaaca atgttttaga
    48061 aatagaggtg tactattcta gtttcaatct actataacat cgcttccgaa tccatttgca
    48121 tctactgaac ttttttacaa aaataaaaat cagtagactc gagttcctac tgatttttga
    48181 tagaattcgt ttggattatg cagccaaaac tttgcgtcct ttacgacgac gagctgccaa
    48241 tacgcgacga ccatttttag ttgacatacg gttacggaat ccgtgtttgc gcgcacgacg
    48301 aagtttactt ggttgataag tacgtttcac gatgaatacc tcctcataga ttttgtattc
    48361 gtttagccgg ctataaagtg atcagttact aaacatactt tactattcta tctgattctt
    48421 tcacttttgt caatagctct aggcaaatgt ttccagcttt ttcgaatgca agcc
//
LOCUS       DAVBEM010000008        46483 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVBEM010000008 DAVBEM010000000
VERSION     DAVBEM010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46483
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.008"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            <1..398
                     /locus_tag="VQ548_000497"
     CDS             <1..398
                     /locus_tag="VQ548_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET2653408.1"
                     /translation="EIIAYNLSISPNLEQVQTMLEQAFTEKHYENTILHSDQGWQYQH
                     DSYHQFLEGKGIQASMSRKGNSQDNGMMESFFGILKSEMFYGYEKSFQSLNQLEQAIV
                     DYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
     gene            complement(527..730)
                     /locus_tag="VQ548_000498"
     CDS             complement(527..730)
                     /locus_tag="VQ548_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2653409.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(723..1805)
                     /locus_tag="VQ548_000499"
     CDS             complement(723..1805)
                     /locus_tag="VQ548_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET2653410.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1931..2713)
                     /locus_tag="VQ548_000500"
     CDS             complement(1931..2713)
                     /locus_tag="VQ548_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HET2653411.1"
                     /translation="MVYTSLSSKDSNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2713..4056)
                     /locus_tag="VQ548_000501"
     CDS             complement(2713..4056)
                     /locus_tag="VQ548_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HET2653412.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQSL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4155..5471)
                     /locus_tag="VQ548_000502"
     CDS             complement(4155..5471)
                     /locus_tag="VQ548_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HET2653413.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5664..6885
                     /locus_tag="VQ548_000503"
                     /pseudo
     CDS             5664..6885
                     /locus_tag="VQ548_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
     gene            7084..8658
                     /locus_tag="VQ548_000504"
     CDS             7084..8658
                     /locus_tag="VQ548_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2653414.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            8922..9710
                     /gene="codY"
                     /locus_tag="VQ548_000505"
     CDS             8922..9710
                     /gene="codY"
                     /locus_tag="VQ548_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HET2653415.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9710..10285
                     /locus_tag="VQ548_000506"
     CDS             9710..10285
                     /locus_tag="VQ548_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET2653416.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDFFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10367..10452
                     /locus_tag="VQ548_000507"
     tRNA            10367..10452
                     /locus_tag="VQ548_000507"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10401..10403,aa:Leu,seq:aag)
     gene            10735..11865
                     /gene="ugpC"
                     /locus_tag="VQ548_000508"
     CDS             10735..11865
                     /gene="ugpC"
                     /locus_tag="VQ548_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HET2653417.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            12366..13124
                     /locus_tag="VQ548_000509"
     CDS             12366..13124
                     /locus_tag="VQ548_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET2653418.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGLSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKVLTGEMTLMKLSGMIYDEGWLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            13211..13723
                     /locus_tag="VQ548_000510"
     CDS             13211..13723
                     /locus_tag="VQ548_000510"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HET2653419.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            13905..14849
                     /locus_tag="VQ548_000511"
     CDS             13905..14849
                     /locus_tag="VQ548_000511"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HET2653420.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            14858..15535
                     /locus_tag="VQ548_000512"
     CDS             14858..15535
                     /locus_tag="VQ548_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HET2653421.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVRSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            15633..16391
                     /locus_tag="VQ548_000513"
     CDS             15633..16391
                     /locus_tag="VQ548_000513"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HET2653422.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16429..17934
                     /gene="lytC"
                     /locus_tag="VQ548_000514"
     CDS             16429..17934
                     /gene="lytC"
                     /locus_tag="VQ548_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HET2653423.1"
                     /translation="MSVTFFIGEERLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSTEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAESDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTGTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPHYSGKKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            18430..18948
                     /locus_tag="VQ548_000515"
     CDS             18430..18948
                     /locus_tag="VQ548_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HET2653424.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            19078..19584
                     /locus_tag="VQ548_000516"
     CDS             19078..19584
                     /locus_tag="VQ548_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HET2653425.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            19584..19754
                     /locus_tag="VQ548_000517"
     CDS             19584..19754
                     /locus_tag="VQ548_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653426.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            19786..21018
                     /gene="clpX"
                     /locus_tag="VQ548_000518"
     CDS             19786..21018
                     /gene="clpX"
                     /locus_tag="VQ548_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HET2653427.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            21027..21614
                     /locus_tag="VQ548_000519"
     CDS             21027..21614
                     /locus_tag="VQ548_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HET2653428.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            21625..22005
                     /locus_tag="VQ548_000520"
     CDS             21625..22005
                     /locus_tag="VQ548_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HET2653429.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            22057..22947
                     /gene="rapZ"
                     /locus_tag="VQ548_000521"
     CDS             22057..22947
                     /gene="rapZ"
                     /locus_tag="VQ548_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HET2653430.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            22944..23921
                     /locus_tag="VQ548_000522"
     CDS             22944..23921
                     /locus_tag="VQ548_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HET2653431.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            23918..24829
                     /gene="whiA"
                     /locus_tag="VQ548_000523"
     CDS             23918..24829
                     /gene="whiA"
                     /locus_tag="VQ548_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HET2653432.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(24863..25831)
                     /locus_tag="VQ548_000524"
     CDS             complement(24863..25831)
                     /locus_tag="VQ548_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET2653433.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWTLAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            25967..26824
                     /locus_tag="VQ548_000525"
     CDS             25967..26824
                     /locus_tag="VQ548_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HET2653434.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            26811..27590
                     /locus_tag="VQ548_000526"
     CDS             26811..27590
                     /locus_tag="VQ548_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HET2653435.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            27614..28966
                     /locus_tag="VQ548_000527"
     CDS             27614..28966
                     /locus_tag="VQ548_000527"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HET2653436.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAIQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            29040..29414
                     /locus_tag="VQ548_000528"
     CDS             29040..29414
                     /locus_tag="VQ548_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HET2653437.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            29416..30264
                     /locus_tag="VQ548_000529"
     CDS             29416..30264
                     /locus_tag="VQ548_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2653438.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            30541..31308
                     /locus_tag="VQ548_000530"
     CDS             30541..31308
                     /locus_tag="VQ548_000530"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HET2653439.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDDMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            31320..32504
                     /locus_tag="VQ548_000531"
     CDS             31320..32504
                     /locus_tag="VQ548_000531"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HET2653440.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            32501..34372
                     /locus_tag="VQ548_000532"
     CDS             32501..34372
                     /locus_tag="VQ548_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2653441.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDSKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(34515..35699)
                     /gene="mntE"
                     /locus_tag="VQ548_000533"
     CDS             complement(34515..35699)
                     /gene="mntE"
                     /locus_tag="VQ548_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HET2653442.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPISEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            36003..38699
                     /locus_tag="VQ548_000534"
     CDS             36003..38699
                     /locus_tag="VQ548_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HET2653443.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            38712..39503
                     /gene="yghU"
                     /locus_tag="VQ548_000535"
     CDS             38712..39503
                     /gene="yghU"
                     /locus_tag="VQ548_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HET2653444.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            39619..40029
                     /locus_tag="VQ548_000536"
     CDS             39619..40029
                     /locus_tag="VQ548_000536"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET2653445.1"
                     /translation="MEKKIVKDILFLSQVSHPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGMQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            40041..41636
                     /locus_tag="VQ548_000537"
     CDS             40041..41636
                     /locus_tag="VQ548_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653446.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            41803..41967
                     /locus_tag="VQ548_000538"
     CDS             41803..41967
                     /locus_tag="VQ548_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HET2653447.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            42046..42774
                     /gene="yaaA"
                     /locus_tag="VQ548_000539"
     CDS             42046..42774
                     /gene="yaaA"
                     /locus_tag="VQ548_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HET2653448.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(42825..44309)
                     /locus_tag="VQ548_000540"
     CDS             complement(42825..44309)
                     /locus_tag="VQ548_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2653449.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEGYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYISGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            44525..>46483
                     /locus_tag="VQ548_000541"
     CDS             44525..>46483
                     /locus_tag="VQ548_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2653450.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAVSVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTGEV
                     TKPAEKVEEAKDKKEEVTHQDAIDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIQSSIIGLELRSNSNKGTVSETPVAKKANIVEAKEETN
                     PAATTDRSAVDSAVLPTSTAAKVETTSAPASINEILKPGLSLSDARQNPAIRKEDVDR
                     GYSGFRAAPAPTNQPVTNLGNNTVFTDISRGSHTFRGNGNSRRGNPIHFDVTTTRVRN
                     RVDFSIRYSGPGEFVNNNFILDKGNGFGEPSRATVSTPKLRDQVKNISKGGNFVSHSG
                     YSLEAAVETSTNQTIKFSLPIANPNGDLSVRLRPVTFNVGQGESGSATSNDPYSNSNY
                     YFREKPLLLDANPNGGTNNKTVSEDIDFQTVYLPTSKLPEGQTRLVREGEKGQRQIIY
                     KVHQLGNETILGLPISNSVIKEVKPRIMQIGVAKDLIDTVKPRVDQNKVGDTNNLTFY
                     LDNDGNGVYTEGVDELVQKIAIKDGAKGEKGDRGERGLTGAQGAKGEKGDRGERGLTG
                     AQGAKGEKGDRGERGLTGAQGAKGEKGDR"
BASE COUNT        13861 a         8604 c        10514 g        13504 t
ORIGIN      
        1 gtgaaattat cgcctataat ctttcaattt cacccaactt agaacaagta caaacaatgt
       61 tggaacaagc cttcacagag aagcactacg agaatacgat tctccatagt gaccaaggct
      121 ggcaatatca acacgattct tatcatcagt ttcttgaggg taagggaatt caagcatcta
      181 tgtcacgcaa gggaaacagc caagacaacg gtatgatgga atctttcttt gggattctga
      241 aatcggaaat gttttacggt tatgagaagt cgtttcagtc gcttaatcaa ttggaacaag
      301 ctattgtaga ctatattgat tactacaaca ataaacgaat taaggtaaaa ctaaaaggac
      361 ttagtcctgt gcaatacaga actaaatcct tcggataaat taattgtcta actgtttggg
      421 ggcagtacat attcaacacc tgatactatg cgttttattg tgggaagatt ttcctcattt
      481 tctagtgaaa ttgaactttt tctaacatct tttgatagat gacttcttaa tcaattatca
      541 tttccattgt tgtttcttgg ggtttcatcc cttgtctttg ataaaagcgg agagcaccct
      601 cgttatcatt ccagacactt agggttagat tattgcagcc aatttcttta gcataatagc
      661 agaaaaatga caataaaata gcccctagat attttgaaag gaaagcatag gggctatata
      721 gtttaatcaa aataaagcaa atctttgctg gtgcttgtaa agaggtcgaa gccatccttg
      781 gtaacaacac cgcagtcttc aatacgaaca ccgactttac cagggatata gatacctggt
      841 tcaacagaga agcacatgcc ttcttcgatg accatgtcgt ttccttccat gatagatggg
      901 aattcatgga catccatacc gataccatgc ccgagacggt ggttgaagta ctcaccataa
      961 ccagcttttt cgatgacctc acgggcagcg cggtccactt catgagcagt cacacctggc
     1021 ttgataaagt caagagcagc ttgttgggct tcaagagtca agttgtaaat atctttcttg
     1081 aattggtctg gtttgccgac agcgactgta cgagtcatat ctgacgcata gccattgacc
     1141 agaacaccca ggtcaaagag gagaagagca tcattttcaa ccttattagc tgctggaatg
     1201 ccgtgtggat tcgcagcatt atcaccagtc aagaccatgg tatcaaagct catttcataa
     1261 ccttcacgtt tcatggcaaa gtcgatttgt gcgatgatat ctgtctcagt cttatcaaga
     1321 gaaatattgt caaaaccaac atgaacagcc ttgtcagcat aaagacctgc aaccatcatt
     1381 ttttgcactt catcagctga tttgatgagg cgcatgcgtt ggatacgagg agtgaggttg
     1441 tcaaactcag cagtctcaaa aactgttttc aaaccatggt atttggtcaa gatgagattg
     1501 tcaaactcaa cagcgacacg tttgaagtca agttgtggaa gagcatgttt gattttttgc
     1561 catggatttt cagaatcgac atagcccact actgggaagg aaacggtgct acttgcacgt
     1621 tctacttcaa gagctgggac aaagaggaga ggttcctgat ccgctaggac aaagaggaac
     1681 atttggcgtt catggggatc actgtaaaaa ccagtgaggt aattgattgt gacggggtca
     1741 gatacgacag cgacgtctag tttttctgat tcaagatatg ttaggatttg ttgtaattta
     1801 gacatatgct accttctttc tacccctcta ttttggcaaa aaatgagaga aaatgcaagg
     1861 gagaagggta aaagaaaaga caaaaaactc cgacaagata acggagttct ttgatatcat
     1921 tttcctttgt ttaagaaaag tcagccttgc ttttgacgtc actgtactct tcagcgattt
     1981 cttggctgag aatgtcctca taggcaggga gttggatgtc ctgaccatat ttcttcttga
     2041 gggcagtagt aactaggcga taagccagat tggcattacg agagaggata ggcccgtgga
     2101 agtaggaacc aaagacattc ttataatgaa ccccttcacc gaccttttct tcgttgtttc
     2161 catttccata gacaacctgt cccagcggtt tttggtcatc agagaggaag gtacgacctt
     2221 ggtgattttc aaatccatag taggtttcat cgaaatcttc attgtgaatc ttgatgtcac
     2281 cgataaaacg gttattggtc tggttgagcg tgtagtgtcc catgacccct agcccttcga
     2341 tacgttttcc tgaagcttca acataatatt gacccaatag ttggaaacca ccgcagatag
     2401 ccagaactac accgtcgttt tggatgtagt tgtcaatgct ctctttttta gcaggtaggt
     2461 cgtctgcaat gatactttgt tcaaagtctt gaccaccacc gaaaaaggcg atgtcgtagt
     2521 gattttcatc aaagtcatca tggagagaaa cgatgtcaac ggtcacatgg gctcccagtt
     2581 tttcagccac atacttgagc atgaggatgt ttccattgtc cccgtaggta ttcatgagat
     2641 ttccgtagag gtgggcaatg ttgagctgat aggggtaatt gctatctttt gaggaaagtg
     2701 aagtataaac cattagttca tctcctttct aacaatctga cgactagcca gcagttcacg
     2761 aaattccagc atggcagtat aagttgccag aatataggca tgcttgcagt cttgattctc
     2821 aatggtcttg agaacttgct ccagattact cgtttcagtg attttctcag ctggatagcc
     2881 agtcactcgg aggcgacgag cgatttcaga atgacgaaca ccgccagcgt tgatttcagg
     2941 aatgtccatg tcagtgattt gctcaaagtc tgcatcccag atccagctag tgtcaattcc
     3001 atctgcatag ttggcattaa ggaggacaga taggctaaat ggataaggtg ctagtttgat
     3061 catttcgata gcttgggttg caccgactgg atttttaatc aagacaaggg tacattcctt
     3121 gtcaccgata tgaaaggttt cttggcgtcc aaagacagca cggctcttgt caaatccctg
     3181 tttgatgagt tgggaatctg cgccgaggaa acgggcgatg gccacagcag ctagggcgtt
     3241 atagatatta tagagcccgc cgatttggat accgtattct tggccgtcta tgacaaagcg
     3301 agagcgattg ttggtcaact caaccagttt tgtcaaacga tagtcgagat caggacgttt
     3361 acatccacaa ccttcacaga tataggcacc caagtttgca taggtattat gctcatattt
     3421 gaggatgcct tggcagtcag gacagagaat cccttcggta ttgtagtgag ccagttgggc
     3481 tggtcctttt tccaagtcaa aaccaaaata ctctataggg tttggaatag ttggcttgta
     3541 gaaaagtgga ctgtctccgt taaggagaac agtagcagtt ggaacttttc gaatggcatc
     3601 caatatcatg ttataggtag tatagatttc accgaaacgg tccatctggt cacggaagat
     3661 attagtaatg acaaaaagac taggctggat atagtcacag atacgagata gactggcttc
     3721 gtcaatttcg aggacggcaa tatttttccc agtttttgaa gatttggctg ttaggaaggt
     3781 tgttgcaatc cctgtaatca tgttggcacc gcttgggttg gttagaactt gaccataaac
     3841 ctcttttaaa atgccgacag tgagggcagt tgtcagggtt tttccatttg ttccagtgac
     3901 aacgacaatc tcgtagttct tagctaggct ttgtaaaata tctttatcaa attgaagggc
     3961 gactttccct gggagcgtac ttccacgtcc aagacggctt aaaacgaagt gggaagaacg
     4021 cccagcaaga aggcccaaag tagtttttaa gttcatgttt ctattatatc acaaaagagg
     4081 gaaaagacag atttggtgtt tcgtagaagt aaaaacagcc caaagagggc tgtcagttaa
     4141 gatgagattt caacttaaat cgcaaacaag tcattcaagt tctcagccaa ggttgggtga
     4201 gtgaagattt gttttgtgaa gtaagtgtaa ggaatcttgt tgtccatagc aacagtaatg
     4261 atgttgatga tttcttgaga accttctgag aagatgcttg caccaagaat ttcttttgtt
     4321 tcagtattaa caacagcttt gaaagctccg cgaaggtctc catttacgtg accacgaggc
     4381 atggctgcaa cagggatttc tttcactgcg tatggaagtt tcaaatcagc tgcttggctt
     4441 tcagtcaaac caacttgtga aagtgcaggt gtgatgaaca tagtatttgg cacattgaga
     4501 cggtcctcaa gtgtgtagct gccatctcca gcaaggtagc tgtaaacaac acggaagtca
     4561 tcaagtgaaa tgtaagtaaa ttgaaggcca ccgttgacat ctccaactgc aaagacacca
     4621 ggaacgtttg tttgacagtg tttgtctact ttaatagcac cacgttcagt tagttcaata
     4681 tctgtatttt caagttgaag tggttctaca tttggtttgc gtccagttgc gtagagaagg
     4741 gcgtcgaaac ggtaagtttc gtcttcagtt acgacaagca cttggtcacc atcgtttttg
     4801 atttcagtag tatggatatt ttgaagcaat tcaatgccat cttcttccat gtattgttta
     4861 gcaagagctg cgatggaagg ttctgcacga ggtaggaatg tatccaaggc atctaggact
     4921 gtgaccttgc ttccaagttt gttgtaaagg ccggcaaatt caagaccgat atttccgcca
     4981 ccaaggattc caagtttttc aggtaatttg tccaagcttt ggatacctgt tgagtcaaag
     5041 atgtttttgc ttgtagcaag tccaggaatt ggcaagacgt ttgaaacagc accagtgttg
     5101 atgacgattg tttcagcagt cagttctttc ttttcatcac cagcttggat ttcgatgact
     5161 ttatttgaaa ggaagtgagc ttccgcatca aagatatcta cgcctgtacc agcaacagtc
     5221 gcatagtttt taccgttgag gcgaccagtg atcgtgtttt tagtagcaat cacttcttca
     5281 aaagacaagt ccttttcagc agcaactagc aaggttttag ttgggataca accaatgttg
     5341 atacaagttc caccgtacat agccttgctg cgttcaacga gggcaacttt tttgccagct
     5401 gaagccaatt tacctgctag tgttttacca gctttaccaa atccaataac aattaaatcg
     5461 tatgttaaca tttatcttcc tcctattcga atttcattct agcacaagaa aaaaactttt
     5521 gcacaattct gctacggaaa agacagaaaa agataaaaac gctttccaga caaaaaacta
     5581 gtaatttttt gacaagcttg ataaactaaa atcctatcta tttttatata agaaagaata
     5641 aatgttcgaa aataggaggt tttatgaaat cgaatcgtta tattattgcc tttgctgggg
     5701 tcattttaca cttaatgctg ggttcgactt atgcttggag tgtttatcgt aaccctatta
     5761 ttgaaaaaac gggatgggat caggcttctg ttgccttcgc ctttagtcta gcaatctttt
     5821 gtttgggctt atcggctgca tttatggggc gtttggtaga aaaatttggt ccgaaagtca
     5881 tggggagtct atctgctttt ctatacgcag gtggaaatat cttaacagga tttgcaatag
     5941 accgtcagga actgtggttg ttgtatctag cttatggcat tttaggtggg cttggtttgg
     6001 gagcaggcta tattacccct gtgtcaacga ttataaaatg gtttcctgat aaacgtggtc
     6061 tcgcaacagg tttagcgatt atggggtttg gttttgcttc tttattgact agtcccatag
     6121 cgcaacacct catcgcaggg gtagggattg tagaaacttt ttatatttta ggagcaagtt
     6181 actttattat catgctccta gcttcacaat tcattaagcg tccaaatgag caagagcttg
     6241 caattttatc ttcttcaggg aaagaaaaaa cagcctcttt gacgcaagga atggctgcaa
     6301 atcaggctct aaaaagcaat cggttttata tgctttggat tattttcttt atcaacatag
     6361 cttgtggttt aggcttaatt tcagcggcat cgccaatggc acaggagatg gctggcttgt
     6421 ctacaagtca tgcagcagta atggtgggtg ttttggggat tttcaatgga tttggtcgct
     6481 tgctctgggc gagtttgtct gactatatcg gtcgccctct aacctttagt atattactgc
     6541 ttgtcaatct tttctctctc actttggctc tttacagatt ccgttttatt tgtagttgct
     6601 atgtctattt tgatgacttg ctatggagct ggtttttctt tgattccagc ttatctcagt
     6661 gatatttttg gaaccaagga attggccgct ctgcatggtt atattttaac agcttgggca
     6721 atggctggtt tagcgggacc tattttatta gcagagactt ataaaatggc tcattcgtac
     6781 acacaaacct tgttcgtttt tctcatttta tacagtatcg ccttggcttt gtcttattat
     6841 ctaggtcgtt caatcaaaaa agaaagtcaa aaaccgctta catgattttc tgtagaaatg
     6901 gggctatctt ttgctctggt cttgtgttat actagatagg ttgcaaagaa aacagtactt
     6961 ttcttttgtg gaaaagaagc aacacgattt tatatctagt tatatgaaaa tacgtcataa
     7021 aaagaaaagt ataaactaag ccctataggg tggcttcgca ccacctttag aaagaagaat
     7081 aacgtgaaat ttaatgaatt aaacttgtct gctgatttgc tagcagaaat tgaaaaagct
     7141 ggttttgtag aagctagtcc tatccaagaa caaactattc ctttggccct tgaaggcaag
     7201 gatgttatcg gtcaagctca gactggtaca ggaaaaactg cagcctttgg cttgcctacc
     7261 cttgaaaaaa tccgtacaga agaagcgact atccaagctt tggtcatcgc tccaactcgt
     7321 gaactagctg tccaaagtca agaagaactc ttccgctttg gtcgtagtaa gggagtcaaa
     7381 gtccgttcag tatatggcgg atcaagcatt gaaaaacaaa ttaaggctct taaatctggt
     7441 gcccatatcg tggtgggaac tccaggtcgc ctcttggact tgattaaacg caaggccttg
     7501 aaattacaag acattgaaac ccttatcctt gacgaagcgg atgaaatgct taacatgggc
     7561 ttccttgaag acatcgaagc cattatttcc cgtgtacctg agaaccgtca aactttgctt
     7621 ttctcagcaa ctatgccaga tgccatcaaa cgtatcggtg ttcagtttat gaaagcccct
     7681 gaacatgtca agattgcggc taaggaattg acaacagaat tggttgacca gtactatatc
     7741 cgtgttaagg aacaagaaaa atttgacacc atgactcgtc tcatggatgt ggcacaacca
     7801 gaactcgcta ttgtatttgg tcgtaccaaa cgccgtgtgg atgaattgac tcgtggtttg
     7861 aaaattcgtg gcttccgtgc agaaggaatt catggcgacc tagaccaaaa caaacgtctt
     7921 cgtgtccttc gtgactttaa aaatggcaat cttgatgttt tggttgcgac agacgttgca
     7981 gcgcgtggtt tggatatttc aggtgtgacc catgtctaca actacgatat tccacaagat
     8041 cctgagagtt atgttcaccg tatcggtcgt acaggtcgtg ctggtaagtc aggtcaatct
     8101 attacttttg ttgctccaaa cgaaatgggt taccttcaaa tcattgaaaa cttgactaag
     8161 aaacgcatga aaggtctcaa acctgcaagt gtagaagaat ccttccaatc aaaaaaacag
     8221 gtagctctca agaaaatcga acgtgatttt gcagatgaaa ccattcgtgc caactttgag
     8281 aaatttggta aggatgctcg caaattggct gctgagttta ctccagaaga attggcaatg
     8341 tatatcttga gtctgacagt ccaagaccca gatagccttc cagaagtgga gattgcacgt
     8401 gaaaaaccac taccgtttaa accatcaggt aatggtttcg gtggtaaagc taagggaggt
     8461 cgtggaggcc gtcgtgggga cgaccgtcga gagcgtgatc gccgtggcaa tggtcgccgt
     8521 gatgagttca aaaaaggaag tcgtggcaac gatcgttttg ataaggaaaa acgttaccgt
     8581 aaggataata aaaaaccacg caatacttta agcgaaaagc aaacaggctt tgttattcgt
     8641 aacaaaggcg ataaataaga aaaagcggtt caaaatgaat cgctttttta tataaggaga
     8701 ccgaatgtga aaagacaaat aaaattacta tattatcttt tataatgtta tgatacacaa
     8761 aaataggcaa cttgtcaata gaaaaggaac aatttaatta aaaatattct ggtttttaat
     8821 taaattgtaa gtcaatgcaa gtcaataagg aattttcaga taattattga aaaagagacg
     8881 tttttatgtt ataatgatag cgattaaatt cgaggtgaaa aatggcacat ttattagaaa
     8941 aaactagaaa aattacatca attttgaaac gctcagagga gcagttgcag gatgagctcc
     9001 cttacaacgc tattacgcgt cagttagcgg atattattca ttgcaatgcc tgcattatca
     9061 atagtaaggg acgtctgctt ggctatttta tgcgttataa aacaaataca gatcgcgtag
     9121 agcaattctt ccaaactaag attttcccag atgactacgt tcaaggggct aatatgattt
     9181 acgaaacaga agcaaacttg cctgttgagc atgatatgag tattttccct gttgagagta
     9241 gagatgattt tccagatggc ttgacgacta ttgcaccgat tcatgtatcg gggattcgcc
     9301 ttggttcttt gattatttgg cgtaatgata aaaaattcga agatgaggac ttggttcttg
     9361 ttgagattgc cagtaccgtt gttgggattc agcttcttaa cttccaacgt gaagaagatg
     9421 agaaaaatat tcgtcgtcgt actgctgtca ccatggcggt caataccctt tcttactccg
     9481 aactccgtgc tgtttcagca attttagggg aattaaatgg aaatgaaggg aagttgactg
     9541 cgtcagtgat tgcagatcgt atcggaatca ctcgctctgt gattgtcaat gctcttcgta
     9601 aacttgagtc tgcggggatt attgaaagtc gctcacttgg aatgaaggga acctatctta
     9661 aggtcttgat ttcagatatt tttgaagaag tgaagaaaag agattactaa tgacaaaggc
     9721 tttaatttcg attgattata cagaagattt tgttgctgat agtgggaagc tgacagcagg
     9781 tgctccagct caggcgattt cggatgccat cagcaaggta actcgattag cttttgaacg
     9841 aggagattat atcttcttta ctattgatgc tcatgaagaa aacgattttt tccatccgga
     9901 aagtaagtta tttcctcctc ataatctgat tgggacgagt ggacggaatt tatatggaga
     9961 tttggggatc ttttatcaag agcatggttc agacagtcgt gtcttttgga tggataaacg
    10021 ccattactca gctttttcag ggactgacct agatattcgt ttgagagagc gtagagtgtc
    10081 taccgttatc ttaacaggtg tcttgacgga tatctgtgtc ctacatacag ctatagatgc
    10141 ctataatcta ggatatgaca tcgagattgt taaaccagct gttgcttcca tctggcctga
    10201 aaatcatcaa tttgccctag gtcatttcaa aaatacactc ggagctaagt tagtagatga
    10261 aaatctaaat gaactttctg agtaacctgg ttggtgaaaa tgaaaaaatt tgaaaaaaag
    10321 tgttgacaag catcccaaaa gttgatatac tagtaaagta atcgatgcgg ggatggcgga
    10381 attggcagac gcgcaggact aaggatcctg tgaccgcttt aggtcgtgag ggttcaagtc
    10441 cctctctccg cataggaaaa gagttagcta aagctagctc ttttgtattt ctctaaaaaa
    10501 ttagaatcca gtcaaatgta gtggagaatc agcgaaaata tgggaaaact gttccttgtt
    10561 tctgcttttg tcatagaaga ataataaaga ttatcttctt caaattctcc gatattctct
    10621 aaagttttgt gcaagttgca cagaactttt ttattttttt ggtcatcttg ccatagaaat
    10681 ataaagcgtt ttcatctata atataattat caaaagacaa aaggagttca cctcatggta
    10741 gaattgaatc ttaaaaatat ttacaaaaaa tatccaaaca gcgaacacta ttcagttgaa
    10801 gatttcaact tgaacatcaa agataaagaa tttatcgttt tcgtaggacc ttcaggatgt
    10861 ggtaaatcaa ctacactccg tatgattgct ggtcttgaag acattacaga aggtactgca
    10921 tctatcgatg gcgtggttgt caacgacgta gctccaaaag accgtgatat cgccatggta
    10981 ttccaaaact acgctcttta cccacacatg actgtttatg acaacatggc tttcggtttg
    11041 aaattgcgta aatacagcaa agaagacatt aacaaacgtg ttcaagaagc agctgaaata
    11101 cttggattga aagaattctt ggaacgtaaa ccagctgacc tttcaggtgg tcaacgtcaa
    11161 cgtgttgcca tggggcgtgc gattgtccgt gatgcgaaag tattcttgat ggacgaacct
    11221 ttgtcaaact tggatgccaa acttcgtgta tcaatgcgtg ctgaaatcgc taaaattcac
    11281 cgtcgtatcg gagctacaac tatctatgta actcacgacc aaacagaagc gatgacactt
    11341 gcagaccgta tcgttattat gtcagctact aagaaccctg ctggtacagg tactatcgga
    11401 cgtgtagaac aaatcggtac tcctcaagaa gtttacaaaa atccagttaa caaattcgtt
    11461 gcaggattca tcggaagccc agctatgaac ttcatcaacg tgaaattggt tggtagcgaa
    11521 attgtttctg acggtttccg tttgaaagtg ccagaaggag cattgaaagt tcttcgtgaa
    11581 aaaggctacg aaggaaaaga attgatcttt ggtatccgtc cagaagacgt gaatgcagaa
    11641 cctgctttcc ttgaaacatt cccagactgt gttgtaaaag cgactatctc tgtatcagaa
    11701 ctgcttggtt cagaatctca cctttactgc caagttggta aagacgagtt tgttgcaaaa
    11761 gttgatgctc gtgactactt gcaaacaggt gcaacagttg agcttggatt tgacttgaac
    11821 aaagcacact tcttcgatgt agaaactgaa aaaacaatct actaaaataa ataaaattca
    11881 aagcactaca agaaaagata tctctttatc aattgtagtg gagagatatc agttaatcta
    11941 gggagagaaa caaaatgctt ctctcctttt tgctagggaa gtcatattat gcatctatat
    12001 tgtgatgctc tttaatactc ttcgaaaatc tcttcaaacc acgtcaacgt cgccttgccg
    12061 tacgtatgat tactgatttc gtcagtttta tctgcaacct caaagatgta ctttgagcag
    12121 cttacggcta gtttcctagt ttgctctttg atttccattg agtattattt gtgggtacca
    12181 tctacaagtg aagctatatg cgtaaactac gtgagcaatt gaattcgaac tagagaggta
    12241 ataataaatt tatgctatag ttatggtgac ttgtatgctt ttgattctag tttatcaaat
    12301 aatagattag aattgtcaga taatatcatt ttgtgttata atgaagaaaa aacagaggtg
    12361 ttcaaatgtc agaagcaggt cataagtttt tagcaaaatt ggggaaaaaa cgcttacgtc
    12421 caggtggaaa gcgtgctaca gattggttaa ttgcagaagg aggattgtca aaagaaaaga
    12481 gaatactaga ggttgcgtgt aataggggaa ctacagcaat tgagttggca cagcgttttg
    12541 gttgcaagat aactgctgtt gatatggatg ctcaagcttt agaagtggct aaaaaatctg
    12601 ctggaacggc aggtgttgct catttaatca gttttgaaag agcaaatgca atgaaacttc
    12661 cttatcaaga tgctagtttt gatattgtta taaatgaagc tatgctgact atgcaagccg
    12721 atcaagctaa gaaaaaatgt gtaatggaat atctaagggt attaaaacct ggaggtcttc
    12781 ttttgacaca tgatgtgctt cttaaggaag ctaaagagtc tatcagacag gaattatcac
    12841 aagcaattca tgtaaatgta ggtcctttaa ctcaagatgg ttgggaacag gtgatgatag
    12901 aatcaggtta ttgtgatgtg aaagtattga ctggtgaaat gacattaatg aaattatcgg
    12961 gtatgattta tgacgaaggt tggctaggaa ctttgaaaat ttgtgtaaat gcttgtaaaa
    13021 aggagaatag aaagcagttt ttaactatgt ataaaatgtt tgctaagaat aaacagaaat
    13081 tgggctttat tgcgatggct agttataaat cgtcaaaacg ttagataatt attgaagtta
    13141 acttttcctt ttttctttct taaaaaatat gctataatag agagtgaaaa actttgaaag
    13201 aaagaaaaag atgaatttaa aagattacat tgcaacaatt gaaaattatc caaaggaagg
    13261 cattaccttc cgtgatatta gtcctttgat ggctgatgga aatgcttata gctacgctgt
    13321 tcgtgaaatc gttcagtatg ctactgacaa gaaagtcgac atgatcgtgg gacctgaagc
    13381 tcgtggattt atcgtgggtt gtccagttgc ctttgagttg ggaattggtt ttgcgcctgt
    13441 tcgtaagcca ggtaaattgc cacgcgaagt tatttctgct gactatgaaa aagagtacgg
    13501 tgtcgatacc ttgactatgc acgcggatgc cattaagcca ggtcaacgtg ttcttattgt
    13561 agatgacctt ttggcgacag gtggaactgt taaggcaact atcgagatga ttgaaaaact
    13621 tggtggtgtt atggcaggtt gtgccttcct tgttgaattg gatgaattga acggccgtga
    13681 aaaaatcggt gactacgact acaaagttct tatgcattat taatgaaaac agtccctagg
    13741 gctgttttct ctacactagg atataaaaat agactataac tagttagaga aaaactataa
    13801 ttgaaaacta tatcttcttg cagtataata aaaggactaa gtgtttgaga tttgtcttca
    13861 aacacatgca attattcctg agagagtaca gttaggagag ggttatgccg attcgaattg
    13921 ataaaaaatt gccagctgtt gagattttac ggacagagaa tatctttgtc atggatgatc
    13981 aacgtgctgc ccaccaagat atccgtcctt tgaagatttt aattttaaat ctcatgccac
    14041 agaaaatggt cacagagacc cagttgttgc gtcacttggc taatacaccc ctacaactgg
    14101 atattgattt tctctatatg gagagccacc gttctaaaac aactcgttca gagcacatgg
    14161 agaccttcta taaaactttt cctgaagtca aggatgagta ttttgatggg atgatcatca
    14221 cgggtgctcc agttgagcat ttaccatttg aggaagtgga ctattgggag gaatttaggc
    14281 agatgcttga gtggtctaag acacatgtct attcgaccct tcatatctgt tggggggctc
    14341 aggctgggct ttatctgcgc tatggtgtag aaaaatacca gatggacagt aagctatcag
    14401 gtatttatcc tcaggacacc ctaaaagagg gtcaccttct atttagaggc tttgatgata
    14461 gctatgtatc ccctcattca cggcacacgg agatttctaa ggaagaggtc ttaaacaaga
    14521 ccaatctcga gattttatca gaaggacctc aggttggggt ttctattttg gccagtcgtg
    14581 atttacgaga aatttatagt tttggtcatt tggagtatga ccgtgatacc ttggcaaaag
    14641 agtattttcg agatcgtgat gcaggtttcg acccacatat tccagaaaat tactttaaag
    14701 atgatgatgt taatcaggta ccttgtcttt gttggtcttc atctgcagcc ctctttttca
    14761 gtaattgggt aaaccatgcg gtctatcagg agacgccttt tgattggaga aagatagaag
    14821 atgatgcatc tgcatatggg tatttataag aggaattatg acatatttag acgcttttaa
    14881 atcaggtacc ttggttttac cgagtgccct gctcttgcat tttaaggaac tctttccttc
    14941 tagcgacgat tttctggttt ggcaattttt ctatttgcaa aatacgacag gcttagaaga
    15001 aatgtcgcca agccagattg ctgaaaggat tggcaaggaa atttcggatg tcaaccagtc
    15061 catttctaat ctgacggaaa ggggactgct ccagtatcgt actatcgaat taaatggcga
    15121 aattgaattg ctctttgatg ctagtttggc cttggaacgt ttggatgacc tgtttggagc
    15181 agttcgttca agttcagacc agctaacacc tcaaaaccag ctcaaggatt tggtggaaac
    15241 cttccagcag gagttgggac gattgttgac gccttttgag attgaggatt tgaccaagac
    15301 actaaaggaa gatggaacca gtgctgactt gattaaggag gctcttcgtg aagctgtttt
    15361 gaatggaaaa ccaaactgga agtacattca ggcgattttg agaaactggc gccatgaagg
    15421 aatcaagagt gtggctcaaa ttgaggccaa gagagcagaa agagaagcaa gcaatcctca
    15481 gttgacacag gtatctgcag atttcagaaa tgccatggat ctctggaagg attaatccat
    15541 gcaagtaggc ttgaaatccg agtaagattt gcaagctgtg tataattgtg atagaataaa
    15601 tagaaaataa attgaaaaaa gaggtatgtg aaatgtcacg taaaccattt atcgctggta
    15661 actggaaaat gaacaaaaat ccagaagaag ctaaagcatt cgttgaagca gttgcatcaa
    15721 aacttccttc atcagatctt gttgaagcag gtatcgctgc tccagctctt gatttgacaa
    15781 ctgttcttgc tgttgcaaaa ggctcaaacc ttaaagttgc tgctcaaaac tgctactttg
    15841 aaaatgcagg tgctttcact ggtgaaacta gcccacaagt tttgaaagaa atcggtactg
    15901 attacgttgt tatcggtcac tcagaacgcc gtgactactt ccatgaaact gacgaagata
    15961 tcaacaaaaa agcaaaagca atctttgcga acggtatgct tccaatcatc tgttgtggtg
    16021 aatcacttga aacttacgaa gctggtaaag ctgctgaatt cgtaggtgct caagtatctg
    16081 ctgcattggc tggattgact gctgaacaag ttgctgcctc agttatcgct tatgagccaa
    16141 tctgggctat cggtactggt aaatcagctt cacaagacga tgcacaaaaa atgtgtaaag
    16201 ttgttcgtga cgttgtagct gctgactttg gtcaagaagt cgcagacaaa gttcgtgttc
    16261 aatacggtgg ttctgttaaa cctgaaaatg ttgcttcata catggcttgc ccagacgttg
    16321 acggtgccct tgtaggtggt gcgtcacttg aagctgaaag cttcttggct ttgcttgact
    16381 ttgtaaaata atcagtaagt agcaaaagct aggtggaaca gcattcagat gtctgttaca
    16441 ttttttatag gagaggaaag attgaaaaca aaaattggat tagcaagtat ctgtttacta
    16501 ggcttggcaa ctagtcatgt cgctgcaaat gaaactgaag tagcaaaaac ttcgcaggat
    16561 acaacgacag cttcaagtag ttcagagcaa aatcagtctt ctaataaaac gcaaacgagc
    16621 acagaagtac agactaatgc tgctgcccac tgggatgggg attattatgt aaaggatgat
    16681 ggctctaaag ctcaaagtga atggattttt gacaactact ataaggcctg gttttatatt
    16741 aattcagatg gtcgttactc gcagaatgaa tggcatggaa attactacct gaaatcaggt
    16801 ggatatatgg cccaaaacga gtggatctat gacagtaatt acaagagttg gttttatctc
    16861 aagtcagatg gggcttatgc tcatcaagaa tggcaattga ttggaaataa gtggtactac
    16921 ttcaagaagt ggggttacat ggctaaaagc caatggcaag gaagttattt cttgaatggt
    16981 caaggagcta tgatgcaaaa tgaatggctc tatgatccag cctattctgc ttatttttat
    17041 ctaaaatccg atggaactta tgctaaccaa gagtggcaaa aagtgggcgg aaaatggtac
    17101 tatttcaaga agtggggcta tatggctcgg aatgagtggc aaggcaacta ctatttgact
    17161 ggaagtggtg ctatggcgac tgacgaagtg attatggatg gtgctcgcta tatctttgcg
    17221 gcctctggtg agctcaaaga aaagaaagat ttgaatgtcg gctgggttca cagagatggt
    17281 aaacgctatt tctttaataa tagagaagaa caagtgggaa ccgaacatgc taagaaaatc
    17341 attgatatta gtgagcacaa tggtcgtatc aatgattgga aaaaggttat tgatgagaac
    17401 gaggtggatg gtgtcattgt tcgtctaggt tatagcggta aagaagacaa ggaattggcg
    17461 cataacatta aggagttaaa ccgtctggga attccttatg gtgtctatct ctatacctat
    17521 gctgaaaatg agaccgatgc tgagagtgac gctaaacaga ccattgaact tataaagaaa
    17581 tacaatatga acctgtctta ccctatctat tatgatgttg agaattggga atatgtaaat
    17641 aagagcaaga gagctccaag tgatacaggc acttgggtta aaatcatcaa caagtacatg
    17701 gacacgatga agcaggcggg ttatcaaaat gtgtatgtct atagctatcg tagtttatta
    17761 cagacgcgtt taaaacaccc agatatttta aaacatgtaa actgggtagc ggcctatacg
    17821 aatgctttag aatgggaaaa ccctcattat tcaggaaaaa aaggttggca atatacctct
    17881 tctgaataca tgaaaggaat ccaagggcgc gtagatgtca gcgtttggta ttaagcgatg
    17941 atttgaaaga gggatgtgat agtagcaccc tctttttctt tgttttatga tagttcatcc
    18001 tcgagtaaat tcaagttctt gctcggaaat gaagcttata tagtagattg aatatagaca
    18061 aataccttgt gattggtaaa acattttaga aattcattta cctttcctaa tcgacttggt
    18121 ttcatcttat ttcaatctat tatagtattg gggaatttct tcaaaccaca tcagcttggt
    18181 cagttctacc tgcgacctca aaacttgtgc tttggtcaag ctgggtttag tttcctagtt
    18241 tgctgatgga tttccattga ctataagcat ccaaccctct ttttgtcttc taaagaattc
    18301 ttaaattatc agtctattgc aacttttctc atataagttc tttgtcttgc tattggtttt
    18361 ccttagtagt atactaaggt agtaatcatt aagaagtggt tacaaaaaat aatgaatgag
    18421 gtaaagaaaa tggtagaatt gaaaaaagaa gcagtaaaag acgtaacatc attgacaaaa
    18481 gcagcgccag tagcattggc aaaaacaaag gaagtcttga accaagctgt tgctgatttg
    18541 tatgtagctc acgttgcttt gcaccaagtg cactggtata tgcatggtcg tggtttcctt
    18601 gtatggcatc caaaaatgga tgagtacatg gaagctcttg acggtcaatt ggatgaaatc
    18661 agtgaacgct tgattacact cggtggaagc ccattctcta cattgacaga gttccttcaa
    18721 aatagtgaaa tcgaagaaga agctggtgaa taccgtaatg ttgaagaaag cttggaacgt
    18781 gttcttgtta tctaccgtta cttgtcagaa cttttccaaa aaggtttgga tgtcactgat
    18841 gaagaaggtg acgatgtgac aaacggtatc tttgcaggcg ctaaaactga aacagataaa
    18901 acaatttgga tgcttgcagc cgaacttgga caagcacctg gtttgtaaga aataaggaaa
    18961 catagataaa tctgtaggaa atttcttaca gattttttct attttgtaag ctattccaaa
    19021 ccagtctttt tttgagtttt ttgataaaat agtactatca gtgaaaagga tggaagcatg
    19081 actaagaaaa tcgtagctat ttgggcccag gatgaagagg gtgtgattgg taaggaaaat
    19141 cgtctgcctt ggcatttgcc agcagaattg cagcacttta aagaaacaac tctgaatcat
    19201 gctatcttga tggggcgtgt gacctttgat gggatggggc gtcgcttgct tccaaaacgg
    19261 gaaaccttga ttttgacgcg taatccggaa gaaaagatag atggggttgc tacttttcag
    19321 gacgtccagt ctgttcttga ctggtatcag gctcaagaaa agaatctcta cattatcggt
    19381 gggaagcaaa tttttcaggc ttttgaacct taccttgatg aagtgattgt cactcacatt
    19441 catgctcggg tggaaggaga tacctatttc cctgaagaac ttgacttgtc tctttttgag
    19501 acagtttcaa gcaaatttta cgccaaagat gagaagaatc cttatgattt taccatccaa
    19561 taccgcaaga gaaaggaagt ctaatggaac ggagtttatt tggtctattc acggcttttc
    19621 tgtgtttcat ctgctttctg gcaggagcac aagcttttcg taaaaagcgt tacgggcttt
    19681 ctatcctcct ttggttaaat gcctttacca atctggtcaa tagtattcat gctttttaca
    19741 tgaccttatt ttagatagaa tgacagtata gaatggaagg aaatcatgtc tacaaataga
    19801 aaaaatgata tgatggttta ttgctcattt tgtggcaaaa accaagaaga agtacaaaaa
    19861 ataattgctg gcaacaatgc ttttatttgt aatgaatgcg tggagttagc tcaggaaatc
    19921 attcgagaag aattggttga ggaagtcttg gcagacttgt ctgaggtgcc aaaaccaatt
    19981 gaactcctcc atatcttgaa ccactatgta attggtcaag atcgtgccaa gcgtgccttg
    20041 gcagtggcgg tttataacca ctacaaacgc atcaatttcc acgatacacg cgaagagtca
    20101 gaagatgtgg atttgcagaa gtcaaacatt ttgatgattg gcccaactgg ttcagggaaa
    20161 actttccttg cccagacctt ggctaagagc ttgaatgtac cttttgctat tgcggatgcg
    20221 acagctctga cggaggctgg ttatgtgggt gaggatgtgg aaaatatact cctcaaactc
    20281 ttgcaggttg ctgactttaa catcgaacgt gcagagcgtg gcattatcta tgtggatgaa
    20341 attgacaaga ttgccaagaa gagtgagaat gtgtctatca cacgtgatgt ttctggtgaa
    20401 ggggtgcaac aagcccttct caagattatt gagggaactg ttgctagcgt accgcctcaa
    20461 ggtggacgca aacatccaca acaagagatg attcaagtgg atacaaaaaa tatcctcttc
    20521 atcgtgggtg gtgcttttga tggtattgaa gaaattgtca aacaacgtct gggtgaaaaa
    20581 gtcatcggat ttggtcaaaa caataaggcg attgacgaaa acagctcata catgcaagaa
    20641 atcatcgctg aagacattca aaaatttggt attatccctg agttgattgg acgcttgcct
    20701 gtttttgcgg ctcttgagca attgaccgtt gatgacttgg ttcgcatctt gaaagagcca
    20761 agaaatgcct tggtgaaaca ataccaaacc ttgctttctt atgatgatgt tgagttggaa
    20821 tttgacgacg aagcccttca agagattgct aataaagcaa tcgaacggaa gacaggggcg
    20881 cgtggacttc gctccatcat cgaagaaacc atgctagatg ttatgtttga ggtgccgagt
    20941 caggaaaatg tgaaattggt tcgtatcact aaagaaactg tcgatggaac ggataaaccg
    21001 atcctagaaa cagcctagag gtgactatgg aacttaatac acacaatgct gaaatcttgc
    21061 tcagtgcagc taataagtcc cactatccgc aggatgaact gccagagatt gccctagcag
    21121 ggcgttcaaa tgttggtaaa tccagcttta tcaacactat gttgaaccgt aagaatctcg
    21181 cccgtacatc aggaaaacct ggtaaaaccc agctcctgaa cttttttaac attgatgaca
    21241 agatgcgctt tgtggatgtg cctggttatg gctatgctcg tgtttctaaa aaggaacgtg
    21301 aaaagtgggg gtgcatgatt gaggagtact taacgactcg ggaaaatctc cgtgcggttg
    21361 tcagtctagt tgaccttcgt catgacccgt cagcagatga tgtgcagatg tacgaatttc
    21421 tcaagtatta tgagattcca gtcatcattg tggcgaccaa ggcggacaag attcctcgtg
    21481 gtaaatggaa caagcatgaa tcagcaatca aaaagaaatt aaactttgac ccaagtgacg
    21541 atttcatcct cttttcatct gtcagcaagg cagggatgga tgaggcttgg gatgcaatct
    21601 tagaaaaatt gtgaggaaaa gaaaatggca aaaacaattc atacagataa ggccccaaag
    21661 gctatcggac cctatgttca aggaaaaatc gttggcaacc ttttgtttgc tagcggtcaa
    21721 gttcccctat cccctgaaac tggggaaatt gtaggagaga atatccaaga acagacagag
    21781 caagtcttga aaaacatcgg tgctattttg gcagaagcag gaacagactt tgaccatgtt
    21841 gtcaaaacaa cttgcttctt gagcgatatg aacgactttg ttccttttaa tgaggtttac
    21901 caaacggcct tcaaagagga attcccagct cgttcagctg tggaggtagc tcgtcttcct
    21961 cgtgatgtaa aagtcgaaat tgaagtcatc gcagagattg gataagctag ttgaagtttg
    22021 gtgttgccaa acttcttttg atataaggag aaaaagatga caaagaaaca acttcacttg
    22081 gtgattgtga cagggatgag tggcgcaggg aaaactgtag ccattcagtc cttcgaggat
    22141 ctaggttatt tcaccattga taatatgccg ccagctctct tgcctaagtt tttgcagctg
    22201 gttgaaatta aggaagataa tcctaagttg gctttggtag tggatatgcg tagccgttct
    22261 ttcttttcag agattcaagc tgttttggat gagttggaaa atcaagatgg tttggatttc
    22321 aaaatcctct ttttggatgc ggctgataag gaattggtcg ctcgttacaa ggaaaccaga
    22381 cggagtcacc cactagcagc agacggtcgt attttagatg gaatcaagtt ggaacgtgaa
    22441 ctcttggcac ctttgaaaaa tatgagccaa aatgtggtgg atacgactga actcactcca
    22501 cgtgaactgc gcaaaaccct tgcagagcag ttttcagacc aagaacaagc ccagtctttc
    22561 cgtatcgaag tcatgtcttt cggatttaag tatggaatcc cgattgatgc ggacttggtc
    22621 tttgatgtcc gtttcttgcc aaatccctat tatctaccag aactgagaaa ccaaacgggt
    22681 gtggatgaac ctgtttatga ttatgtcatg aaccatcctg agtcagaaga cttttatcaa
    22741 catttattgg ccttgattga gccgattctg ccaagttacc aaaaggaagg taagtccgtt
    22801 ttgaccattg ctatgggatg tacgggtgga caacaccgta gtgtggcatt tgctaaacgc
    22861 ttggcgcagg acttatccaa gaattggtct gttaatgaag ggcatcgcga caaagaccgc
    22921 agaaaggaaa cggtaaaccg ttcatgagaa aaccaaagat aacggtgatt ggtggaggga
    22981 ctggaattcc cgtcattcta aaaagtctgc gggaaaaaga tgtggaaatc gcagctatcg
    23041 tgacggtggc agatgatggt ggttcttcag gtgaactccg aaaaaatatg caacagttga
    23101 caccgccagg tgatcttcgt aatgtccttg tggccatgtc ggatatgcct aagttttatg
    23161 agaaggtctt tcagtatcgg ttctctgagg atgccggagc ctttgctggc catccattgg
    23221 gaaatctcat cattgctggc ttgtcagaaa tgcagggttc aacctataat gccatgcagt
    23281 tattgagcaa atttttccat acaacaggga aaatttatcc ttccagtgac catcctttga
    23341 cccttcatgc agtctttcag gatgggacag aagtggctgg agagagtcat attgtagacc
    23401 atcgaggcat aattgacaat gtctatgtga ccaatgccct aaacgatgat acgcctctgg
    23461 ccagccgtcg agtagtgcag accatccttg aaagtgacat gattgtccta gggccaggtt
    23521 ccctctttac ctctattttg cccaatatcg tgattaagga aattgggcgg gctcttttgg
    23581 aaactaaggc agaaattgcc tatgtctgca atatcatgac ccaacgtggg gagacggaac
    23641 actttacaga tagcgaccac gtggaagtct tgcatcgtca ccttggtcgc ccttttatcg
    23701 acactgtctt ggtgaatatt gaaaaagtgc ctcaggaata catgaattcc aaccgttttg
    23761 atgaatactt ggtgcaagtg gaacacgatt ttgtaggtct ttgtaagcaa gtttcgcgcg
    23821 tgatttcatc taacttcctt cgtctggaaa atggcggtgc cttccacgat ggagatttga
    23881 ttgtggacga gttgatgcgc attatacagg tgaaaaaatg agtttcacag tagcagtaaa
    23941 agaagaaatc ctgggccaac accatctgag ccggcatgaa ttatctgcca ttatcaaaat
    24001 gtctggtagc atcggtctct cgacttcggg cttgactttg tcagttgtga cagaaaatgc
    24061 caaactggcc cgtcacctct atgagtcctt tctccatttc tatgaaatca aatctgaaat
    24121 tcgtcaccac caacggagca atcttcgcaa gaatcgcgtc tataccgttt ttacagatga
    24181 aaaggtgcag gatttgttaa gtgatttgca cttggcagac tctttctttg gcctggaaac
    24241 aggtattgat gaggcgattt tatcggatga ggaagcaggt cgtgcctatc tctgtggcgc
    24301 tttcttggca aatgggagca ttcgtgaccc tgagtcaggc aagtaccagt tggaaatcag
    24361 ttctgtttat ctggaccacg cgcaaggaat tgcctccctt ctccaacagt ttttactgga
    24421 tgccaaggtg cttgagcgca agaagggggc tgtgacctat ctccagcgag cagaagacat
    24481 tatggacttc ttgatagtaa tcggagccat gcaggcacgt gatgattttg agcgggttaa
    24541 gattttgcga gaaacccgta acgacctcaa tcgggctaat aatgccgaga cagctaatat
    24601 cgctcggaca gtttctgcca gcatgaagac cattaacaat atcagtaaaa taaaagatat
    24661 catgggctta gaaaatttgc cagtagattt gcaggaagtg gcgcaactga ggattcagca
    24721 cccagactac tctatccagc agttagcaga tagtctcagc acccctctga ccaaaagtgg
    24781 tgtcaatcac agactcagaa aaatcaataa gatagcggat gaattataaa accacgaatc
    24841 ctatgtgact cgtggttctt ttttataaac tggtagagtg ttttggttgt actttttgtt
    24901 cagggtcaat gtagttgata gcgttgttga cagcagttgg agcttctccg aggcctgtcg
    24961 caatcagatc aatttttccg tcatagtagc agcagtcacc gatagcatag atacctgctt
    25021 ggctggattc ctgtttgctg ttgacgataa tcttgtgacg gttgaggtcg agcccccagt
    25081 ttttaaggtt accgacagaa gatttgaaac catagttgac aaagaggtgg tctaggtcaa
    25141 tggtttcagt ttcatcagat ttgacttttg tgatttcaag tttatcaagt gtttttccat
    25201 ttccaaggag ttggctaggg gcgaatggtg tcttgatggt tacagatgat tcttgcaagg
    25261 cttgaacact gtgttccaag gcacggaaat tatctctgcg gtgaacaagg gtagttggtg
    25321 cgattttttc aaaagccaaa gtccaatcca cagccgagtc tcccccacca agaatcgtca
    25381 cttttttacc agcgtattgc tgaatgttag aaacgtggta gtggatattt tcatagccct
    25441 caaccccttc aagttccagc ggacgtggtt tgaaggcacc gccacccata gcgatgataa
    25501 ctgttttagt caggtgactt cctttagaag ttgtgatggc aaattcttct tcttgtttgt
    25561 caatctcaag aaccgtttca ttgagatgaa taggggtatc aaatccattt agctgttcaa
    25621 tcaagcggtt agtcaactct tctccagtca ggtttgggaa gcctggtacg tctaggattt
    25681 ccttttcagg gtagagaata gcaggttgtc cacctagctg gggaagagag tcgatgattt
    25741 gaaccttggc ttggcgtagg tgggcataaa aggctgcaaa aagcccgaca ggaccaccac
    25801 ccacaatggt aatatcatag agttgagaca tagtttctcc tttgtttttt ctagtcagtt
    25861 tattttatca tatttttgtt caatgtaaaa tggactagga tagggaaaaa aatgccagaa
    25921 aatggtataa taggacgaaa gtgttttgat agggaggata tcagggatga attttcaaca
    25981 attatccaat ttgcaatatt ggaccagttt gtttgcaagt ccatggacga tagctatcaa
    26041 tctgattgat attttgattg ttgcttatat tttataccat tttacaaaag ctattgcagg
    26101 aaccaagatt atgattttgg tacgtggagt tttggtattt attttagctc aaatccttgc
    26161 aaatatgatt ggtttgacta cgatttcttg gttaatcaat caaattatta cttatggggt
    26221 tattgcggcg gttgttatct tctctccaga gattcggact ggtttggaac gtttgggaag
    26281 agcgacagat ttcttttcca atgcccctat tagtgctgag gaacagatga ttcgtgcctt
    26341 tgttaagtct gttgaataca tgagtcctcg taaaatcggg gccttggttg ctattcagcg
    26401 tgtacgtacc ttgcaggagt atatttcgac aggaattccc ttggatgcta agatttctgc
    26461 agaacttctc attaacattt ttattcccaa cactccccta catgacggtg cggtgattat
    26521 caaagaagaa cgtatcgctg tgacgtctgc ctatctgccc ttgacaaaaa acacagggat
    26581 ttccaaggaa tttgggacca gacaccgggc ggctatcggt ttatcagaag tctcagatgc
    26641 cttgactttt gtcgtatcag aggaaacggg aggaatttcg ataacctata atggaaggtt
    26701 taagcacaac ctaacacttg atgaatttga aacagaatta cgtgaaatct tacttccaaa
    26761 agaggaagta ggtcttagtt ttaaagaacg attgctagga ggatggaaac atgaaaaaaa
    26821 atagtttata tatcatatcc tcactctttt ttgcttgtgt cttatttgtc tatgctacgg
    26881 cgacgaattt tcaaaacagt accagtgcta ggcaggtaaa aacggaaacc tatactaata
    26941 cagtaacaaa tgtccctatt gacatacgct ataatagtga taagtatttt attagcggtt
    27001 ttgcttcaga agtatcagtg gtcttgactg gtgcaaatcg cctatcgcta gctagtgaaa
    27061 tgcaagaaag tacacgtaaa ttcaaggtta ctgctgacct aacagatgcc ggtgttggaa
    27121 caattgaagt tcctttgagc attgaagatt tacccaatgg gctgaccgct gtggcgactc
    27181 cgcaaaaaat tacagtcaag attggtaaga aggctcagaa ggataaggta aagattgtac
    27241 cagagattga ccctagtcaa attgatagtc gggtacaaat tgaaaatgtc atggtgtcag
    27301 ataaagaagt gtcgattacg agtgaccaag agacattgga tagaattgat aagattatcg
    27361 ctgtcttgcc aactagcgaa cgcataacag gtaattacag tggttcagta cctttgcagg
    27421 caatcgaccg caatggtgtt gtcttaccgg cagttatcac tccgtttgat acaataatga
    27481 aggtgactac aaaaccagta gcaccaagtt caagcacatc aaattcaagt acaagcagtt
    27541 catcggagac atcttcgtca acgaaagcaa ctagttcaaa aacgaattaa aaatagaaaa
    27601 ggattttata acaatgggta aatattttgg gactgatgga gtccgtggag aagctaacct
    27661 agaactaaca ccagaattag cctttaaact aggacgtttt ggaggctatg ttcttagtca
    27721 acatgaaacg gaagcgccga aagtctttgt aggacgtgac acacgtattt caggggaaat
    27781 gctagaatcg gccttggtgg caggtctcct ttcagtaggg attcacgtat acaaacttgg
    27841 tgtccttgca acaccagcag tagcttactt ggttgaaact gaaggagcaa gtgctggtgt
    27901 catgatttct gctagccaca atccagctct tgataacgga atcaagttct ttggcggtga
    27961 tggcttcaaa ctagatgatg aaaaagaagc agaaattgaa gccttgctag atgctgagga
    28021 agacactctt cctcgtccaa gtgcagaagg cttaggaatt ttggtagatt atccagaagg
    28081 cttgcgtaag tatgaaggat accttgtttc aactggaact cctcttgatg gaatgaaggt
    28141 tgccttggat acagctaatg gagcagcttc taccagtgcc cgtcaaatct ttgcagacct
    28201 tggtgcccaa ttgacggtta tcggggaaac accagacggt cttaacatca accttaatgt
    28261 tggttcaaca catccagaag cccttcaaga agtggtcaaa gaaagtgggt cagctattgg
    28321 tttggccttt gatggagaca gtgaccgctt gattgctgtt gatgagaatg gtgacatcgt
    28381 cgatggtgac aagattatgt acatcatcgg aaaatacctt tctgaaaaag gacaattggc
    28441 tcaaaataca attgtgacaa ctgttatgtc taaccttggt ttccacaagg ccttgaatcg
    28501 cgaaggtatt aacaaggcag ttactgcagt tggtgaccgc tacgttgttg aagaaatgag
    28561 aaaatcaggt tacaaccttg gtggtgaaca gtctggtcac gttatcttga tggattacaa
    28621 taccacaggt gatggtcaat tatcagcaat tcaattgact aaaatcatga aggaaactgg
    28681 taagagctta tcagagttgg cggcagaagt aacgatttat ccacaaaaat tagttaatat
    28741 ccgagtggaa aacgtcatga aggaaaaggc catggaagtg ccagctatca aggccatcat
    28801 cgagaagatg gaagaagaaa tggcggggaa cggccgtatc cttgttcgtc caagtggaac
    28861 agagcccctc ttgcgtgtta tggcagaagc gcctacaaca gaagaagtgg actactatgt
    28921 tgatactatc acagatgtag ttcgtgctga aattgggatt gactaaatcc tagaaaacta
    28981 gatgaaaata aaaaattatg gtacaatagc ttataatatt gtagccgatg gagaaagaca
    29041 tgaatcttaa acgtgaacaa gaatttgtta gtcagtatca ttttgatgca cgtaattttg
    29101 aatgggaaaa tgaaaatgga gctcctgaaa ccaaggtgga tgtgaatttc caattgctcc
    29161 aacatgacca agaaaatcaa gtgacttcct tgattgtcat tttgagcttt atgattgtat
    29221 ttgataagtt tgtcattagt ggaacaatct cacaagtaaa ccatatcgat ggccgtattg
    29281 tcaatgaacc aagtgaattg aaccaagaag aggtggaaac cttggctcgt ccatgtttga
    29341 acatgctcaa tcgtttgact tacgaagtga ctgaaattgc attagactta ccaggaatta
    29401 atttggagtt ctaatatgaa attagctgtt ttcacagatt cctctgctta tctcagtgaa
    29461 gagaccttgc aaagagaaga cttgtttgtc ttggatattc ctgtcaatat tgatggtgag
    29521 gaatatgtcg aaggcatcaa tctgtctgct gaggaatttt accaaaaaat ggctcaggct
    29581 tctgaattgc ctaagaccag tcaaccaagt attgccaagt tagatgagat cttaacttcg
    29641 ctcaaagaac aaggctatac acatgccttg gggcttttcc tatcttctgg aatttcaggt
    29701 ttttaccaaa atatccagta tatggtcgat gactatgagg gcttaaccat tgctttccca
    29761 gacactttga ttacaagtgc tcccctaggc atcatggttg aaagcgtctt taattggcgt
    29821 gatcagggcg atgattttgc cagcattcag gataagctag ccattcaaat cagccgtacg
    29881 tcagccttta tcatggtaga tgacttggat catttggtaa aaggtggacg cctttcaaat
    29941 ggggctgcca ttttgggcaa tttgcttagc attaagccaa tcctttattt taacgatcaa
    30001 ggtgtgattg aagtttacga aaaagttcgt actgaaaaga aggccaccaa gcgcttaatt
    30061 gaaattatca aggaaacaac ggcttcaggt caataccggg tcattgtcat tcatgggaat
    30121 gctcctgaaa aggctgaaga attgcgtcag cacttgcttg attttggctt gggttcggat
    30181 gtttcacttg ctacatttgg tagtgtcatt ggaacgcacc taggagcagg aagtattgct
    30241 ctgggttata ttccagtgat ttagttggcg cttctaggct agttaagatg ccttgtatct
    30301 tagaaattga acacggacta cctgcctctt gaaaaaagat gcctgtcttg cctttcgtgg
    30361 aaagtcagtg ccattcccta tttttcagag gcagctaagg tcctttgtat cttgataatt
    30421 gaacacgcct ggaaccctgt gtgaaaaaga tagttcttcc aagaagtaga cacttcttga
    30481 ttggaattcc tattttcact ttgtgttctt acggactttg tatcttagac aggagtagag
    30541 atgagtattc gagtaattat tgccggtttt aagggaaaga tgggccaggc tgcttgtcag
    30601 atggtattga ctgatccaga cttggacttg gtggcagttt tggatccttt tgagtctgag
    30661 tcagaatggc agggtattcc tgttttcaag gataaggctg atttagctgg ttttgaagcg
    30721 gatgtctggg tagattttac tactccagct gttgcctacg aaaatacacg ttttgctctt
    30781 gaaaatggct ttgctccagt agttggaacg actggtttca cgagtgaaga aattgcagag
    30841 ctaaaagaat tttctcgtgc ccaagacttg ggtggcctga ttgcccctaa ctttgccttg
    30901 ggtgctgtct tactcatgca atttgcgacg caggctgcca aatatttccc aaatgtggag
    30961 attattgagc tccatcatga caagaaaaag gatgctccga gtggaacagc cattaaaaca
    31021 gctgagttga tggcagaggt tcgagagtcc attcagcaag gcgcagcaga tgaggaagag
    31081 ctgattgctg gtgctcgtgg tgctgacttt gatgatatgc gcatccactc agttcgtttg
    31141 ccaggcttgg tagctcatca ggaagtcatc tttggcaatc agggagaagg gttgaccctc
    31201 cgtcatgact cctatgatcg catctccttc atgacaggag tcaatttggg aattaaagaa
    31261 gttgtcaagc gtcatgagct tgtctatgga ttagaacact tattatgaga ttaacgcaaa
    31321 tgccttctga atttcagaag gctttaccag tattagaaaa aattaaagaa gcaggctttg
    31381 aggcttattt tgttgggggc tctgttcgag atgcccttct ccatagccct atccacgatg
    31441 tggatattgc gacgtcttct tatccagaag agaccaagca gatttttccg cgaacagccg
    31501 atatcggaat cgagcatgga accgtcttgg tcttagatgg ggatgaggag tatgaggtaa
    31561 caacctttcg gacagaggat gtctatgtgg actatcgcag acccagtgcg gtttcctttg
    31621 tacgatcgct agaagaagac ctcaaacgcc gtgatttcac agtcaacgcc tttgccttgg
    31681 atgagacagg agaaatcgtt gacttgttcc atggtttaga agatttggaa aagcaagtct
    31741 tgcgagcagt tggagtggct agtgagcgtt tcaacgaaga tgctttacgg attatgcgtg
    31801 gtttccgttt tcaggctagt cttggttttg cacttgagcc agaaacattt aaagctatga
    31861 agaccttgac gccgcttttg gagaaaattt ctgtagagcg taccttcgtc gagtttgata
    31921 aactcttgct ggctccattt tggagaaggg gcttggcttc catgattgag agtcaagctt
    31981 atgactatct ccctgatatg gcatctagcc aggacaagct caacagactg tttgatttgg
    32041 agactgattt tacttttgaa tcctctgaac aagcctgggc ggctttacta tgggctttgg
    32101 agattgaaaa tgcgcagtca tttttgaaat cttggaagac ctcacgccag tttgccaagc
    32161 aagttcagga tttgctgatt attttggctc tgcgtgaaaa tggagaattg agtaagcgag
    32221 attgttatcg ctttgacata gatttgcttt tacaggctga aaatcttcgt caagctcaag
    32281 gaaaagaagt caacccacaa gccatcacag aaaaatacca aagcttgact atccatgaca
    32341 agaaagagat tcagattaat ggcgatattt tgatcaagga atatggctat cagccaggcc
    32401 cagacttggg agagatttta acagagattg agtttgccat tgtcgatgga gaattggaga
    32461 ataatcgtga agccatccat gcttacctga gggagaaaaa atgagtgatt ttatcgttga
    32521 aaaactaagt aaatccgttg gtgacaagac cgtttttagg gatatttcct ttattatcca
    32581 tgacttagac agaattggtt taatcggtgt caatgggact ggcaagacca cccttttgga
    32641 cgtcctttct ggtgtttctg gatttgatgg ggatgtcagt cctttttcag ctaaaaatga
    32701 ttaccagatt ggttacttga ctcaggatcc tgattttgat gatagaaaga cagttttgga
    32761 tacggttcta tctagtgaac tcaaggaaat ccagctcatt cgtgagtatg aattgattat
    32821 gctcgactat agtgaggaca agcaggcgcg tttggaacgt gtcatggcag agatggactc
    32881 tctccaagct tgggaaatcg aaagtcaggt caagaccgtt cttagcaaat tgggcattca
    32941 agacttatct actcctgttg gggaattgtc aggtggtctg agaagacggg tacagttggc
    33001 acaagtctta cttggcaacc acgacctctt gcttttggat gagccgacca accatctgga
    33061 tattgcgatt attgagtggc tgaccctctt tttgaaaaat tctaagaaga ccgtcctttt
    33121 tatcactcac gatcgttatt tcttagacgc tttgtcaaca cggattttcg agttggatcg
    33181 tgcaggcttg accgagtacc agggcaatta ccaggactat gttcgcctaa aggcggaaca
    33241 ggatgagcgc gacgcggctc ttcttcacaa aaaagaacaa ctctacaaac aagaactggc
    33301 ctggatgcgc agacaaccgc aggcgcgtgc gaccaagcag caggcccgta tcaatcgatt
    33361 ccatgatctg aaaaaggaag tttcaggcag tagtgctgag acagacttga ccatgaactt
    33421 tgaaaccagt cggattggga agaaagtcat cgagtttcag gctgtttcct ttgcctatga
    33481 aaacaagcct attttgcaag attttaatct cttggtgcag gccaaagacc gtatcggaat
    33541 cgttggggac aatggtgttg gaaaatcaac cctgctcaac ttgattgcag gaagtcttga
    33601 gccaactaaa ggacaagttg tgattgggga aactgttcgc atcgcctatt tctctcagca
    33661 aattgagggt ttggatgaaa gcaagagagt tatcaattac ctgcaggaag tggcagaaga
    33721 ggtcaagacc agtggcggtt ctacgacttc gattgcagag ttgctggagc agttcctttt
    33781 cccacgttcg acgcatggaa ccttgattga gaaattgtca gggggtgaga aaaaacgtct
    33841 ttatctcctc aaactgcttt tggaaaaacc aaatgttctt cttttagacg agccaaccaa
    33901 tgacctagat attgcaactt tgacagtctt agagaatttc ttgcaaggtt ttgcaggtcc
    33961 cgttttaaca gtcagtcacg accgctattt cttggataag gtagcgacca agattctcgc
    34021 ttttgaggat agcaagattc gtcctttctt tggtcattac accgactatc ttgatgaaaa
    34081 agcttttgaa acagatatgg ccaatcaagt gcaaaaggtc gaaaaggaaa aagtggtcaa
    34141 ggttcgagaa gacaagaaac gtatgaccta ccaagaaaag caggagtggg caagtattga
    34201 aggtgatatt gaaaccttgg aaaaacgtat cgctgctatt gaagaggaaa tgcaggctaa
    34261 cggctctgac tttggtaagc tggctactct ccaaaaagaa ttggatgaga aaaatgaagc
    34321 actccttgaa aaatacgaac gctatgagta tctcagtgaa tttgatagtt aagactattc
    34381 gaaaatcaaa gtgcaaacta tgtcggcttc acattgccga ctcaagtaca gcctgtgacc
    34441 ggcttcctaa tttgcacttt gatttttatt gagtataaaa gaatagaaaa atcccgtctc
    34501 atgaaaggat ttctctattc ttttttggtt tcttgatgaa agatattttg ccaggtttcg
    34561 tggcgacgcc agatactggt atggatgata ccatctaact catagcagat gagtttggtt
    34621 ttttgactga tggaagtaat ttgaatgtcc ttgatagcag aatttaactc ttttttggtc
    34681 ttataagcct ctttatccat ctgctctcca tcttggcgaa tatagacaaa atcatcagtc
    34741 aagagttctt ctagttggtt tccttggtca atcaattgtt cacgcataag caatttttta
    34801 tagacattgt ctaaaatttc atcctcagag ataggtgctg gttcgatatg gacatcggta
    34861 tcaaagacgc caaaacgctc ctccagcata gactcgacct gatccgcgat ttcatggctt
    34921 tcaaaaacag acaagtcagg attcatctct agtgtaatat ccaggtagat gttgctaccg
    34981 taggtgcgac ctctttgcga tttgaccttg ctgattttgg gaatttccat gatagccttt
    35041 tggtagtcct cgagcaggcg gtcgtcaaag ccatctgaaa gactaaagga agactcgatg
    35101 aagatatcat aggcagtctt caagataaag aaagtgatga tgatagcaac cagtttatcc
    35161 acaatcggat aattgaaact actagctagg atggcaatgg cggttccaag tgaggtaaca
    35221 gcgtcagaaa gattgtcctt agcagctgcc ttcagcgcct tggagttgga tttcttactg
    35281 aggcgagtat tgtagagata gaccacaaac ataatcgctg cagaaatgat tcctagagtt
    35341 gcaccaagag gatcaatgac cgtttcttcc cgactgagaa tcttttgaat ggtatctctt
    35401 agaacatcga aaccgacata gaacatgatg atagaagtga tcaagcttgc caaatcttca
    35461 atcttccaat gaccaaaacg gtggtcacgg tctgcaggct ggcgcgccat ccgaatcccg
    35521 attaagaggg ccacatttcc aatgatgtcc gatacgttat taaaaccatc ggccaccaaa
    35581 ctggatgaat gaaggagatg accagctgct aatttggctg cagacaagat caaataggtc
    35641 gaaatactga taatggctcc acgctcagct aacttgagat ttgagataga ttgcttcatt
    35701 caacttcctt tctagtcaca tagcattcta ccattatact ggttttcaag gaaaaattca
    35761 aataaggcag tttttactct ttgaaaactc cccaaaattt ggtataatgg tactactcaa
    35821 gggagtagct ggcagaaacc tgtgatagtg tcgtcattcc gaattttatg ctgaaaagta
    35881 tgctttccgg ccctatctta aacagcgaga cttgttatga ttaacaggtc tctttttgtt
    35941 tgtcgtgaaa agatatgaca gaaagagagt ctgttttgca cacaatgtca aggaggagac
    36001 acatgtcaaa agaacaaaaa cgccaagcgt tttatactca gagccctgaa gaggtcttgc
    36061 aggctgtgga tgcgaccgag caaggtttgt catcaagtga ggcggaaaag cgccttgctg
    36121 aatttgggca caatgaactc gaagaaggcg agaaacgatc aatcttggtc aaattcatcg
    36181 agcaatttaa ggatttgatg attatcatcc tagttgcggc agcaatcttg tcagtcgtga
    36241 cttctggtgg ggaagatatc gcagatgcca ttatcatcct agctgtggtt atcatcaacg
    36301 ctgcctttgg tgtttaccaa gaaggaaaag ctgaagaagc tattgaagcc ctcaaatcca
    36361 tgtctagtcc agttgcccgc gttcttcgtg atggacacat ggcagagatt gactctaaag
    36421 aattggtacc aggcgatatc gttgcccttg aagcaggtga cgtggtacca gcggacctac
    36481 gtttgataga agccaactct cttaaaattg aagaagcagc cttgacaggt gaatctgtac
    36541 cagtcgaaaa agacttgtca gtcgagcttg cgacagatgc tggtattggt gaccgtgtca
    36601 acatggcctt ccaaaactca aacgtaacct atggtcgtgg gatgggtgtt gttgtcaata
    36661 caggtatgta cactgaagtt ggtcatattg ctggtatgct tcaagatgcg gatgagactg
    36721 atacaccact caaacaaaat ttgaacaacc tttctaaggt cttgacctat gctatcttgg
    36781 tcattgccct tgttactttt gtagtgggtg tcttcattca agggaaaaat ccacttggtg
    36841 agttgttgac ttctgttgcc cttgccgttg cagccattcc agaaggactt cctgctatcg
    36901 ttaccatcgt tctttctctt ggtactcaag ttttggccaa acgacattcc atcgttcgta
    36961 agttgccagc agttgaaaca cttggttcaa ctgaaatcat cgcttctgat aagactggta
    37021 cgctgactat gaacaagatg acagtcgaaa aagtcttcta cgatgcggtt ctacatgact
    37081 cagctgatga tattgaacta ggtcttgaaa tgccactact tcgttcagtt gtcttggcca
    37141 atgatacgaa aatcgatgtg gaaggtaact tgattggtga cccaaccgaa acagccttta
    37201 tccaatatgc cttggacaag ggctatgatg tcaaaggttt cttagagaaa tatcctcgtg
    37261 tagctgaatt gccatttgac tctgaccgta agctcatgtc aacagttcac ccattgccag
    37321 atggtcgttt ccttgtagca gtcaagggtg cgccagacca actcttaaaa cgttgtcttc
    37381 ttcgtgataa ggctggggat attgctccga ttgatgagaa ggttacaaat ctcattcata
    37441 caaacaattc tgaaatggct catcaagcct tgcgtgtcct tgcaggtgct tataagatta
    37501 tcgatagtat tccagaaaat ctcacttctg aagagcttga aaatgattta atttttactg
    37561 gtttgattgg gatgattgac cctgaacgtc ctgaagccgc tgaggctgtt cgtgtggcta
    37621 aggaagcggg aatccgtcca attatgatta caggtgacca ccaagacaca gcggaagcca
    37681 ttgccaaacg tttgggaatc attgacgcaa acgatacaga aggtcacgtt ttaactggtg
    37741 ctgaactcaa tgaactgtca gatgaagaat ttgaaaaagt cgttggtcaa tactctgttt
    37801 atgcccgtgt gtctccagaa cacaaggttc gtatcgtcaa ggcttggcaa aaacaaggta
    37861 aagtcgttgc catgacaggt gacggtgtca atgacgcgcc agctctgaaa acagccgata
    37921 tcggtatcgg tatgggaatc actggtacag aggtttctaa gggggcttct gatatgattc
    37981 ttgcagatga taactttgcg actattatcg tcgcagtgga agaaggacgt aaggtcttct
    38041 caaacattca aaagactatt cagtacctac tttctgctaa tactgctgaa gtattaacca
    38101 tcttcctatc aaccttgttt ggttgggatg tcttacagcc ggttcatctt ttgtggatta
    38161 acttggtaac ggataccttc ccagctatcg ctcttggtgt tgaacctgcg gaacctggtg
    38221 tcatgaatca taaaccacgt ggacgcaagg caagcttctt ctcaggtggt gttttgagtt
    38281 ctatcattta tcaaggtgta ctccaagcag ctcttgttat gagtgtttat ggccttgcga
    38341 ttgcttaccc agttcatgtg ggtgacaatc atgctattca tgcagatgcc ctaacgatgg
    38401 cctttgcaac ccttggtttg attcagctct tccatgccta caatgtcaag tctgtctacc
    38461 aatccatctt gacagttggc ccattcaagt ctaagacctt taactggtcc atcttggtat
    38521 cctttatcct tctcatggca acaatcgttg tagaaccgct tgaaggaatc ttccacgtaa
    38581 ccaaactaga cttgtcacaa tggggaattg ttatggctgg aagcttctca atgattatca
    38641 tcgtcgaaat cgttaagttt attcaacgca aactcggttt tgacaagaat gcgatttaag
    38701 ggaggtttcg gatgtcagca tatcaattac cgaccgtatg gcaggatgaa gctagtaatc
    38761 aaggagcttt tacggggcta aacagaccaa cagcaggtgc ccgtttcgaa caaaacttgc
    38821 caaaaggaga acaagctttt cagctttatt cactgggaac accaaatggt gtgaaggtta
    38881 ctatcttatt ggaagaatta ctagaagctg gttttaagga agcggcttac gacttgtata
    38941 agattgctat catggatggg gatcaattcg gctcagactt tgtgaagctc aatccaaatt
    39001 ccaagattcc agccttattg gaccagtcag gtactgaaaa cgtaagagtc tttgagtctg
    39061 ctcatattct tctttacctt gctgagaaat ttggagcctt tttaccaagt aatcctgtgg
    39121 aaaaggtaga agttttgaat tggctattct ggcaagcagg tgcagcacct tttctaggtg
    39181 ggggatttgg acatttcttc aattatgctc ctgaaaaatt ggaatatcct attaaccgtt
    39241 ttacgatgga agtgaaacgc cagttggatt tattggataa ggaattggct cagaaacctt
    39301 atattgcagg caatgactat acgattgcag atattgctat ctggtcttgg tatggacagt
    39361 tagttcaagg aaatctttac caaggttctg caaaattctt ggatgcctca agttatcaaa
    39421 atctagtaaa atgggcagaa aaaattgcca atcgtccagc tgttaagcgt ggcttggaag
    39481 taacttatac agaaattaaa tagcaaaaaa gtcatcttcg gatggctttt tgctacagtt
    39541 gagggaaagg gtttgcagtt atcggctttt gtgctataat tgctataata tagtaaaaag
    39601 caagaggagt gtgaggaagt ggaaaagaaa attgtgaagg atatcttatt tttatctcaa
    39661 gtgtctcatc cggcaagtca ggaggacctt tatcttgcca gagatttgca ggatacactc
    39721 ttagcaaatc gtgatacctg tgttggtcta gctgccaata tgattgggat gcagaagcgc
    39781 gtgattatct ttaatcttgg cttggttccc gtggtcatgt ttaacccagt gcttctgtcc
    39841 tttgaaggat cctatgaggc agaagaaggc tgtttgtcct tggtaggtgt gagatcaact
    39901 aagcgttatg aaaccataag gcttgcctat cgtgacagca agtggcagga acagaccatt
    39961 accttgacag gcttcccagc tcagatttgc cagcatgagc tggatcactt ggaaggacga
    40021 atcatttagg aggaaagcaa atgaaacgaa tagtctttga acttattttt atcgcaacga
    40081 cctggtatat ctttttaccg ccccttaacc tgaccagctg ggaatttctc ttcttcctct
    40141 gtgggcattt gttagttgtg gcaatcttat ttggctttgg caaggggata aaccttgtca
    40201 aaacggttca tgtgcgccac ggtaaggcgg aagctgcctt aaatcttgag ggtttcaaaa
    40261 tcaatcggtt agggaaaatt ctgttagctt cgattggagg aattcttctc ttggcagctt
    40321 tggtttcctt ggtaacttct agcatgtttc aggctaaaaa ttatgccaat gtagtcacgg
    40381 ttacggaaaa agactttact gaatttccta agagtgacac cagtaaggtt cctatcctag
    40441 atagaagtac tgctgaaaaa attggagacc gctacttggg ttccctaacc gataaggtgt
    40501 cgcaatacgt agcggcagat acctataccc aattgacaat tgatgggaaa ccttatcggg
    40561 tcacaccact agaatatgca gaccctatca aatggtttaa caatcaagcc aagggaatcg
    40621 gtgagtatat caaggtggac atggtaactg gaaatgcgga tttggtggac ttgaagacac
    40681 caatcaagta ttcagactcg gagtatttta accgtgatgt caaacgtcac ctgcgcttga
    40741 agtacccgac caaaatcttt aaaactccat cttttgaggt ggacgatgag ggcaatcctt
    40801 tctatgtagc aacggtttac caaaagcaat ttggacttgc tgttcctcgt cctgcttcag
    40861 tcattatctt ggatgctaca aatggagaaa ccaaggaata cagcttatca gatgttccag
    40921 aatgggtgga caggatctat ccagcagagg aaaccattga gcaaatcaac tacaacggca
    40981 agtacaagga cggtttcttg aatgccatga tttccaagaa aaacgtgacc cagacgacca
    41041 atggctataa ttacttgtct atcggtaatg acatctatct ctacacaggt gtgacgtcgg
    41101 ctaatgcgga tgagagtaat cttggtttca tccttgaaaa tatgcgaaca ggagaaatta
    41161 ctaagtatag cttggcttct gcgacagaag aatcagcccg tgaatcagca gaaggtgctg
    41221 ttcaggagaa atcctacaaa gcaaccttcc caatcctcat caacctcaat gacaagcctc
    41281 tctacatcat gggcttaaag gacaatgctg gcttggtcaa agagtacgcc ctggtagacg
    41341 cagtcgagta ccaaaatgtt atcgttgcta ctacagtgga agagatgctc agcaagtatg
    41401 ccaataaaaa cgaccttgaa attgacaatg caacgacaga aagcatcaag ggagtagtag
    41461 cagacctcaa atcagctgtt atcaagggag acactgtcta cttctttaaa gttgatggca
    41521 agatatacaa ggtaaaggct tcagtatccg atgaccttcc ttaccttgaa aatggtaaaa
    41581 ccttcgaagg tcaagtagga aaagacaatt atctcaagac ctttaaagta caataatact
    41641 cttcgaaaat ctctagctct atctgcaacc tcaaaacagt gttttgagca gcctgcggct
    41701 agtttcctag tttgctcttt gattttcatt gagtataaaa aaggtttatt taataaatat
    41761 atgttataat aaggtaaatt aagcctaatg gaggacaaag aaatgggttt ttatttgatg
    41821 gttgcttcaa tgctactcgg actgctcgct ttgaagatag gtttttctca gttcaaggag
    41881 aaaaaagata aattcttatc tatcttaaca agtttagctg gcacagccct tgttctcgtg
    41941 gctgtctggt taggatggcc caaataaata gaaaaacctc ggtcaaaccg aggtttttca
    42001 aatgaatttc ttggttgtgg ctaaaaaata tgctacacta tcaatatgaa aattttaatc
    42061 ccaacagcaa aagaaatgaa cacagacttg ccaagtatcg aggcaattcc tttaaaacca
    42121 gaaagtcaga ccgtgcttga tgccttggct ctctattctg ccagtcaatt ggagagtttc
    42181 tacaaggtat cagctgagaa agcggcggaa gaatttcaaa atatccaagc tttgaaaagg
    42241 caaactgctc aacactatcc agccttgaaa ctttttgatg ggcttatgta ccgcaacatt
    42301 aagagagata agctgaccga ggcggaacaa gattatcttg aaaatcatgt cttcattacc
    42361 tcggctttgt acggtgttgt tccagccttg tcacccatgg ctcctcaccg tttggatttt
    42421 ttgatgaaat taaaagtcgc tggtaagact ttgaagagcc attggaaggc agtctatgat
    42481 gaagctctga agaaggaaga agtgattttc tctctcttgt catcagagtt tgagactgta
    42541 ttttctaagg aaatcagagc aaagatggtg accttcaaat tcatggagga tagaggcggt
    42601 cagctgaaga ttcactcaac tatctccaag aaagcgcgcg gggcctttct aacagcttta
    42661 atagaaaatc aagtacaaac tgtgggggaa gcacgtcgct tgaactttgc tggatttgtt
    42721 taccgagaag atttgtcaca accacaggga ttggtttttg taaaggaagt atagaaatca
    42781 gataagagaa aagtcagcac gattatgctg acttttttga taacttataa agtattggac
    42841 aaatgaatct catttgataa ggtgttaaga tgattaacca aattcatgat tgacagatga
    42901 tttcggcaaa taaacttctt ggtaatccct gaaatataga aattagacac gatgatatcg
    42961 taatctgtct gatttaaaat ctcaggactt gtttttaatt catcccaaat atcgaaggta
    43021 aagcggttat tacagtaata ggaaagcata tcaacaaagg taagggatat agcatggtca
    43081 aagttactga taatcaaaac cttgataggt ggtcgatttt ctaacaactg agtagagagg
    43141 ttttcagcat gggttaagat ggtgtacatc aagtgttcca actgttcagg atggtcatgc
    43201 tgtccaattg cctgacggta ttgagccagt tcttgacgcg cacttcccat aaagtctggg
    43261 aagtaacctt caaatttttt aatcgtcaat gctttttgtt caaataagat tggggtagaa
    43321 aagatttcct gtctttcaaa gaaagcagtg ttgtgtaaat gccaaatcag ctcatcgtgg
    43381 ttagtaaaag taatcttata ttgttttgat aggcgttcta atatttgact aagtaattgg
    43441 taagagtatc ttgcttgact gttatcttct aaagagttga agaattcttg aggatctagg
    43501 aaaatatcat tctgaagaaa agaaataaaa atttgagcga ttgtatctgg agtcatttca
    43561 agcccaaaat gtttagagaa ataagcaagt gtctcctgga aatttggaat gctctttaaa
    43621 agaggataat attctttgta aaagtggttg gggaggtcaa tgaagtgacc atttttaacc
    43681 ctgtggatac tgatagctat catcagtttg tacattctat aaattgaaaa tcgcattgga
    43741 taattcgtga ttttatagaa gaagtcagca aactctgtta aatcttcctc aggaaggtca
    43801 ggaaaaggcc aatctaggaa ataatagcgc tcagaaaagt attgggcaaa aaagtaacga
    43861 atatcgatct catttccacg tatctcggat ggagtaaaag ataattcaat ttgaaactga
    43921 gatgaaagaa cctttgtaat atttctgccc agtcgataga ggttggcact actaaagtaa
    43981 agattttcta ttgttcgata aataggtagc ccctcattga agaacatata ctctagtaat
    44041 tgaaaagatt gagaattagc aagaaaatat tgataaatat cttctacact agtgttaact
    44101 tctaaatcta tcatgattcc gttaacagaa gattggatgt taatagatgg aaaggcaata
    44161 cgtaattcat ttaaatcact ttttaagatt cgttctgtac atcctaattt ttcggctagt
    44221 tcatgtaatt tcatccaatt acgattctga attagggttt ccattaagcg taattgtctt
    44281 tgaacttttg tggataaaag gtttctcata cgggtatttc ctccataatt cattatatct
    44341 ttttttgtct aagtagtata aaaaaattag agcaagaaaa ttgtcgttag taatcggaaa
    44401 aattagaata atataagtgg cttttaagtg caaaaacaga atatattaat tgttcagaaa
    44461 atattgatta atgcctcaaa tagttgtaca ttgtaaacta taaaatacta tctaggagtt
    44521 taaaatgaaa cattcacata aaaaatcatt tgactggtat agcatgcaac aacgttattc
    44581 tattcgtaag tattactttg gtgcagttag tgtcttgctc ggtaccgctt tggtattagg
    44641 tgcagcagct agtgtccaaa cagtacaagc ggaagaaaac aaacaagaaa ctaccaatag
    44701 tatttctgtt ggtaggggag aagcagctac taaaccagca gaggtttctg cgtctaataa
    44761 agagaaaacc tatgcagctc caactgtagc taatccagta gaaacgactc cagttaaaac
    44821 tggagaagtt actaaaccag cagaaaaagt tgaagaagca aaagacaaaa aagaggaagt
    44881 aacgcatcaa gatgctattg acaagtcaaa attgttaacg gctctttcgc gtgctaaaaa
    44941 gttagaaagc aagttatata cagaagcaag tgctgctaac ttgcaaacaa gtatccaagc
    45001 tggtcaaagc ttgcttggga aagcagatgc atctgaagct gaattatcag cagcagagtc
    45061 atctattcaa tcatctatta ttggtctaga acttcgttct aactctaaca aaggaactgt
    45121 atcagaaact cctgtagcga agaaagctaa tatagttgaa gcgaaggaag agactaatcc
    45181 agctgcaaca actgatcgtt cagctgttga tagtgctgtt ttgccaacta gcacagctgc
    45241 caaagtagaa acaacttcag ctccagcatc tattaatgaa atcttgaaac caggtttgag
    45301 cctttctgat gctcgccaaa atccagctat ccgtaaggaa gatgttgata gagggtatag
    45361 tggttttaga gcggcgcctg ctccaacgaa ccaaccagta actaatctag gaaataatac
    45421 tgttttcact gatattagca gaggttctca tactttccgt ggtaatggaa attcacgtcg
    45481 tggaaacccg attcattttg atgtaacaac aactagagtt agaaatagag tagatttctc
    45541 aatcagatat tcaggaccag gtgagtttgt taataacaac tttatcttag acaaaggaaa
    45601 tggattcgga gaaccttctc gtgcaactgt ttcaacacca aaattaagag accaagttaa
    45661 aaacattagt aagggtggaa actttgtttc tcattcaggc tacagtttag aagctgcagt
    45721 agaaacaagc accaatcaaa caattaagtt tagtttacct atagccaacc ctaatggtga
    45781 tctgtctgtt cgattaagac ctgttacttt taatgtaggt caaggggaat caggatctgc
    45841 aactagtaat gatccatata gtaactctaa ctattacttc agagaaaaac cactcctctt
    45901 ggatgcaaat ccaaatggtg gtactaataa taagactgtt tcagaagaca ttgacttcca
    45961 aactgtctat cttccaacta gtaagttacc agaaggtcaa actagattag ttcgagaagg
    46021 tgaaaaagga caacgtcaaa tcatctataa agttcatcaa ttgggtaacg aaacaatcct
    46081 aggattgcca attagtaatt cagttattaa agaagttaag ccacgtatta tgcaaattgg
    46141 tgtggctaaa gatctaatcg atacagtaaa accacgtgtt gatcaaaata aagtcggtga
    46201 tacaaataac ctcactttct atcttgataa cgatggaaac ggtgtttata ctgagggcgt
    46261 agacgaactt gttcaaaaaa ttgctattaa agatggtgct aaaggtgaaa aaggagaccg
    46321 aggcgaacgc ggtctaactg gagctcaagg agctaaaggt gaaaaaggag accgaggtga
    46381 acgcggtcta actggagctc aaggagctaa aggtgaaaaa ggagaccgag gtgaacgcgg
    46441 tctaaccgga gctcaaggag ctaaaggtga aaaaggagac cga
//
LOCUS       DAVBEM010000009        45799 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVBEM010000009 DAVBEM010000000
VERSION     DAVBEM010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45799
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.009"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(15..210)
                     /locus_tag="VQ548_000542"
                     /pseudo
     CDS             complement(15..210)
                     /locus_tag="VQ548_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(272..721)
                     /locus_tag="VQ548_000543"
     CDS             complement(272..721)
                     /locus_tag="VQ548_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET2653451.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(723..1481)
                     /locus_tag="VQ548_000544"
     CDS             complement(723..1481)
                     /locus_tag="VQ548_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET2653452.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(1596..3575)
                     /gene="pknB"
                     /locus_tag="VQ548_000545"
     CDS             complement(1596..3575)
                     /gene="pknB"
                     /locus_tag="VQ548_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HET2653453.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(3572..4312)
                     /locus_tag="VQ548_000546"
     CDS             complement(3572..4312)
                     /locus_tag="VQ548_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HET2653454.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVFMNEEDAE"
     gene            complement(4327..5640)
                     /gene="rsmB"
                     /locus_tag="VQ548_000547"
     CDS             complement(4327..5640)
                     /gene="rsmB"
                     /locus_tag="VQ548_000547"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HET2653455.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(5633..6568)
                     /locus_tag="VQ548_000548"
     CDS             complement(5633..6568)
                     /locus_tag="VQ548_000548"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HET2653456.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(6581..8977)
                     /locus_tag="VQ548_000549"
     CDS             complement(6581..8977)
                     /locus_tag="VQ548_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HET2653457.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLKSQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGTVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(9043..9357)
                     /locus_tag="VQ548_000550"
     CDS             complement(9043..9357)
                     /locus_tag="VQ548_000550"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HET2653458.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(9382..10008)
                     /gene="gmk"
                     /locus_tag="VQ548_000551"
     CDS             complement(9382..10008)
                     /gene="gmk"
                     /locus_tag="VQ548_000551"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HET2653459.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(10138..11751)
                     /locus_tag="VQ548_000552"
     CDS             complement(10138..11751)
                     /locus_tag="VQ548_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HET2653460.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(11942..12196)
                     /locus_tag="VQ548_000553"
                     /pseudo
     CDS             complement(11942..12196)
                     /locus_tag="VQ548_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
     gene            complement(12200..12454)
                     /locus_tag="VQ548_000554"
     CDS             complement(12200..12454)
                     /locus_tag="VQ548_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HET2653461.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            complement(12692..13789)
                     /locus_tag="VQ548_000555"
     CDS             complement(12692..13789)
                     /locus_tag="VQ548_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET2653462.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVLD
                     YQKIADLYTEKGAEMEKFVKNLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKVRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            complement(13799..14539)
                     /locus_tag="VQ548_000556"
     CDS             complement(13799..14539)
                     /locus_tag="VQ548_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2653463.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(14859..15212)
                     /gene="rsfS"
                     /locus_tag="VQ548_000557"
     CDS             complement(14859..15212)
                     /gene="rsfS"
                     /locus_tag="VQ548_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HET2653464.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(15225..15725)
                     /locus_tag="VQ548_000558"
     CDS             complement(15225..15725)
                     /locus_tag="VQ548_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET2653465.1"
                     /translation="MKTAFIIIDVQNILVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(15726..16319)
                     /gene="yqeK"
                     /locus_tag="VQ548_000559"
     CDS             complement(15726..16319)
                     /gene="yqeK"
                     /locus_tag="VQ548_000559"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HET2653466.1"
                     /translation="MSYQDYINCSREALLEKMAEFLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSNQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIANLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            complement(16319..16948)
                     /locus_tag="VQ548_000560"
     CDS             complement(16319..16948)
                     /locus_tag="VQ548_000560"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HET2653467.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(17000..17311)
                     /gene="yhbY"
                     /locus_tag="VQ548_000561"
     CDS             complement(17000..17311)
                     /gene="yhbY"
                     /locus_tag="VQ548_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HET2653468.1"
                     /translation="MSLASKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(17525..18631)
                     /gene="yqeH"
                     /locus_tag="VQ548_000562"
     CDS             complement(17525..18631)
                     /gene="yqeH"
                     /locus_tag="VQ548_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HET2653469.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVATRKAII"
     gene            complement(18634..19224)
                     /locus_tag="VQ548_000563"
     CDS             complement(18634..19224)
                     /locus_tag="VQ548_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HET2653470.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(19176..20084)
                     /locus_tag="VQ548_000564"
     CDS             complement(19176..20084)
                     /locus_tag="VQ548_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET2653471.1"
                     /translation="MVLEKQLGHGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(20141..20701)
                     /locus_tag="VQ548_000565"
     CDS             complement(20141..20701)
                     /locus_tag="VQ548_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HET2653472.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            20840..22049
                     /gene="sstT"
                     /locus_tag="VQ548_000566"
                     /pseudo
     CDS             20840..22049
                     /gene="sstT"
                     /locus_tag="VQ548_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            22117..23070
                     /locus_tag="VQ548_000567"
     CDS             22117..23070
                     /locus_tag="VQ548_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET2653473.1"
                     /translation="MSISQRTTKLILATCLACLFAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(23306..23386)
                     /locus_tag="VQ548_000568"
                     /pseudo
     CDS             complement(23306..23386)
                     /locus_tag="VQ548_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(23441..23665)
                     /locus_tag="VQ548_000569"
     CDS             complement(23441..23665)
                     /locus_tag="VQ548_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory protein Asp5"
                     /protein_id="HET2653474.1"
                     /translation="MIEMLIVLAIILSLALIVLVTIQPRQNQLFSMDATSNIGKPSYW
                     QSNTLVKVLTLLVSLALFVLLLTFMVITYK"
     gene            complement(23670..23849)
                     /gene="asp4"
                     /locus_tag="VQ548_000570"
     CDS             complement(23670..23849)
                     /gene="asp4"
                     /locus_tag="VQ548_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory system protein Asp4"
                     /protein_id="HET2653475.1"
                     /translation="MSEEDLFYKDVEGRMEELKQKPIKKEKETRGEKISKTFSLLLGL
                     MILIGLLFTLLGILR"
     gene            complement(23851..25188)
                     /gene="gtfB"
                     /locus_tag="VQ548_000571"
     CDS             complement(23851..25188)
                     /gene="gtfB"
                     /locus_tag="VQ548_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosylation chaperone
                     GtfB"
                     /protein_id="HET2653476.1"
                     /translation="MIELYDSYSQESRDLHESLVATGLSQLGVVIDADGFLPDGLLSP
                     FTYYLGYEDGKPLYFNQVPVSDFWEILGDNQSACIEDVTQERAVIHYVDGMQARLVKQ
                     VDWKDLEGRVRQVDHYNRFGACFAKTTYSADSEPIMTVYQDVNGQQVLLENHVTGDIL
                     LTLPGQSMRYFANKVEFITFFLQDLEIDTSQLIFNTLATPFLVSFHHPDKSGSDVLVW
                     QEPLYDAIPGNMQLILESDNVRTKKIIIPNKATYERALELTDEKYHDQFVHLGYHYQF
                     KRDNFLRRDALILTNSDQIEQVEAIVEALPDVTFRIAAVTEMSSKLLDMLRYPNVVLY
                     QNASPQKIQELYQLSDIYLDINHSNELLQAVRQAFEHNLLILGFNQTVHNRLYIAPEH
                     LFESSEVAALVETIKLALSDVDQMRQALGKQGQHANYVDLVRYQEIMQTVLGG"
     gene            complement(25181..26692)
                     /gene="gtfA"
                     /locus_tag="VQ548_000572"
     CDS             complement(25181..26692)
                     /gene="gtfA"
                     /locus_tag="VQ548_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosyltransferase GtfA"
                     /protein_id="HET2653477.1"
                     /translation="MTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMIL
                     ADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVL
                     RVFFFDQDKFVTCYLVDENKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAV
                     LYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVIL
                     DRETGIGQVVFEEAQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNADKVDFFI
                     VSTDRQNEVLQEQFAKYTQHQPKIVTIPVGSIDSLTDSSQGRKPFSLITASRLAKEKH
                     IDWLVKAVIEAHKELPELTFDIYGSGGEDSLLREIIANHQAEDYIQLKGHAELSQIYS
                     QYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVE
                     DQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVLHD"
     gene            complement(26704..29076)
                     /gene="secA2"
                     /locus_tag="VQ548_000573"
     CDS             complement(26704..29076)
                     /gene="secA2"
                     /locus_tag="VQ548_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system translocase SecA2"
                     /protein_id="HET2653478.1"
                     /translation="MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFR
                     QRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQVMGAIVMHYGNVAEMNTGEGKT
                     LTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMK
                     AEEKKLIYASDIIYTTNSSLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQ
                     TPLIIAGSPRVQSNYYAIIDTLVTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGID
                     NLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGTGRLMEMTKLQGGLH
                     QAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRI
                     PTNRPRQRIDYPDNLYITLPEKVYASLEYIKQYHAKGNPLLVFVGSVEMSQLYSSLLF
                     REGIAHNVLNANNAAREAQIISESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLIVI
                     GTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKDYQVQDM
                     TQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDIVYKERNRLIDGS
                     RDLEDVVVDIIERYTEEVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRS
                     FMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDNWVEQVDYLQQLSMAIGGQSA
                     SQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP"
     gene            complement(29069..29509)
                     /gene="asp3"
                     /locus_tag="VQ548_000574"
     CDS             complement(29069..29509)
                     /gene="asp3"
                     /locus_tag="VQ548_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp3"
                     /protein_id="HET2653479.1"
                     /translation="MIITQRQSIYWGEVGGTYMYGTTVSYYLDKSVRLYNPLLPSGEI
                     LKTWFSSVNYQAARTQPQLPLLKRKQEYQLSLVFDCQPENGVYTKITFFDRYGDILEK
                     KVEKAKDFIFTYPEDSYTYQVSLLSAGFESLTFYHFSIKEIRSV"
     gene            complement(29506..31041)
                     /gene="asp2"
                     /locus_tag="VQ548_000575"
     CDS             complement(29506..31041)
                     /gene="asp2"
                     /locus_tag="VQ548_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp2"
                     /protein_id="HET2653480.1"
                     /translation="MSKELNILQIGLANWENHYDIPENMSWYYFYPNSSKTLREIIEK
                     EDINRFHAVLIEDGQYSRDLFSYVKYFEPYTLFYNQNLQINDREVVDFLKKRCAQAID
                     FLSPQQLINDLSKSLFGGGYGDKLFPPTIQVNPNFTGAISYQGLDYVSLEGEFGQDFA
                     QLAYWAYNIMVQKTLPIELWLEYEKEGNCDFRLVIRKMWSGSVDDFFEEVIVSEKDLE
                     QALFMDSRDGDYFLSISVEARGRGTIKLGNLHQRWSRKQFGKFVLGGNILHDSKRDEI
                     NYFFHPGDFKPPLTVYFAGYRPAEGFEGYFMMKTLGCPFILFSDPRLEGGAFYLGTDE
                     LEGKVKDTITHYLDYLGFDHKDLILSGLSMGTFPALYYGASFEPHAIIVGKPLANLGT
                     IASRGRLDAPGVSNLAFDCLIHHTGGTSSQDMTELDQRFWKIFKQANFSKTTFGLSYM
                     KDEEMDPQAYEQLVSYLCNTGAKILSKGTAGRHNDDTDTNISWFLHFYRMVLETGFGR
                     EKR"
     gene            complement(31025..32605)
                     /gene="asp1"
                     /locus_tag="VQ548_000576"
     CDS             complement(31025..32605)
                     /gene="asp1"
                     /locus_tag="VQ548_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp1"
                     /protein_id="HET2653481.1"
                     /translation="MYYFIPAWYGSERTWHADITPWYFSHFRLEFDDTFHQIRLFQEQ
                     DIDSRLLVLAYQPHLRYFLYRHGVLETDTYSVFDVMQDFHNLHTQVLSIRDIEWDDDC
                     EFIYSPFTIIVQKNGKKFAKVEHGVEGFISDIQYFEPNGQIHMHHIMDDRGFISSIIF
                     FEDGQAAYQEYLNPKGVWQFRERLKEGGQVEVNPILGYRFKMLTYQNMGDLVAEFFEN
                     YLQTYVKDQDIFMLPSHSHHDQLVLDRLPSTNPKLLSLFIGRNPQDTFRDLDVTFEKS
                     DLILVDREDSLRLLQELYPERMHQCYHLSSFDTRLRLGRSQTKKESIIYFQLDFEQGI
                     DNQALLQVLSFVAENKDTEVIFGAFAASQEQMNEVEGIVESFIQENIQSENLGKAIDY
                     GDAENPLEENQHQDLRLQFVNLNDELDLIKTLEFVRLIVDLNRHPHLYTQIAGISAGI
                     PQINLVETVYVEHLKNGYLLTDVTEFSKAAHYYTDRLKEWNESLIYSIDKIKEHTGQQ
                     FLGKLEKWIEEVKNVKGT"
     gene            complement(32615..33832)
                     /gene="secY2"
                     /locus_tag="VQ548_000577"
     CDS             complement(32615..33832)
                     /gene="secY2"
                     /locus_tag="VQ548_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein translocase subunit
                     SecY2"
                     /protein_id="HET2653482.1"
                     /translation="MTKIYSSIAVKKGLFTLFLLFIYVLGSRITLPFVDLNTKDFLGG
                     STAYLAFSAALTGGNLRSLSIFSVGLSPWMSAMILWQMFSFSKRLGLTSTSIEIQDRR
                     KMYLTLMIAVIQSLAVSLRLPVQSSYSAILVVLMNTILLIAGTFFLVWLSDLNASMGI
                     GGSIVILLSSMVLNIPQDVLETFQTVHIPTGIIVLLALLTLVFSYLLALMYRARYLVP
                     VNKIGLHNRFKRYFYLEIMLNPAGGMPYMYVMSFLSVPAYLFILLGFIFPNHSGLAAL
                     SKEFMIGKPLWVYVYISVLFLFSIIFAFVTMNGEEIADRMKKSGEYIYGIYPGADTSR
                     FINRLVLRFSVIGGLFNVVMAGGPMLFVLFDEKLLRLAMIPGLFMMFGGMIFTIRDEV
                     KALRLNETYKPLI"
     gene            complement(33889..34566)
                     /locus_tag="VQ548_000578"
     CDS             complement(33889..34566)
                     /locus_tag="VQ548_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET2653483.1"
                     /translation="MGISVAKGEYITIVDSDDIVKENMIETLYQQVQEKDADVVIGNY
                     YNYDESDGNFYFYVTGQDFCVEELAIQEIMNRQAGDWKFNSSAFILPTFKLIKKELFN
                     EVHFSNGRRFDDEATMHRFYLLASKIVFINDNLYLYRRRSGSIMRTEFDLSWARDIVE
                     VFSKKISDCVLAGLDVSVLRIRFVNLLKDYKQTLEYHQLTDTEEYKDICFRLKLFFDA
                     EQRNGKS"
     gene            complement(34551..34793)
                     /locus_tag="VQ548_000579"
     CDS             complement(34551..34793)
                     /locus_tag="VQ548_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2653484.1"
                     /translation="MSELISVVVPIYNTGKYLVECVEHILKQTYQNIEIILVDDGSTD
                     NSGEICDAFMMQDNRVRVLHQENKGGQHKLKIWGLV"
     gene            complement(34793..35989)
                     /locus_tag="VQ548_000580"
     CDS             complement(34793..35989)
                     /locus_tag="VQ548_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HET2653485.1"
                     /translation="MRKSIVLAADNAYLIPLETTIKSVLYHNRDVDFYILNSDIAPEW
                     FKLLGRKMEVVNSTIRSVHIDKELFESYKTGPHINYASYFRFFATEVVESDRVLYLDS
                     DIIVTGELATLFEIDLKGYSIGAVDDVYAYEGRKSGFNAGMLLMDVAKWKEHSIVNSL
                     LELAAEQNQVVHLGDQSILNIYFEDNWLALDKTYNYMVGVDIYHLAQECERLDDNPPT
                     IVHYASHDKPWNTYSISRLRELWWVYRDLDWSEIAFQRSDLNYFERSNQSKKQVMLVT
                     WSADIKHLEYLVQRLPDWHFHLAAPCDCSEELTSLSQYTNVTVYQNVLHSRIDWLLDD
                     SIVYLDINTGGEVFNVVTRAQESGKKIFAFDITRKSMDDGLYDGIFSVERPDDLVDRM
                     KNIEIE"
     gene            complement(35998..37218)
                     /locus_tag="VQ548_000581"
     CDS             complement(35998..37218)
                     /locus_tag="VQ548_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 8"
                     /protein_id="HET2653486.1"
                     /translation="MRNTKRAVAFAGDYAYIRQIETAMKSLCRHNSHLKIYLLNQDIP
                     QEWFSQIRIYLQEMGGDLIDCKLIGSQFQMNWSNKLPHINHMTFARYFIPDFVTEDKV
                     LYLDSDLIVTGDLTDLFELDLGENYLAAARSCFGAGVGFNAGVLLINNKKWGSETIRQ
                     KLIDLTEKEHENVEEGDQSILNMLFKDQYSSLEDQYNFQIGYDYGAAAFKHQFIFDIP
                     LEPLPLILHYISQDKPWNQFSVGRLREVWWEYSLMDWSVILNEWFSKSVKYPSKSQIF
                     KLQCVNLTNSWCVEKIDYLAEQLPEVHFHIVAYTNMANELLALTRFPNVTVYPNSLPM
                     LLEQIVIASDLYLDLNHDRKLEDAYEFVLKYKKPMIAFDNTCSENLSEISYEGIYPSS
                     IPKKMVAAIRSYMR"
     gene            complement(37249..39693)
                     /locus_tag="VQ548_000582"
     CDS             complement(37249..39693)
                     /locus_tag="VQ548_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_1767 family glycosyltransferase"
                     /protein_id="HET2653487.1"
                     /translation="MIKTIVLAGDRNYIRQLETTIKSILYHNRDVKIYILNQDIMPDW
                     FRKPRKIARMLGSEIIDVKLPEQTVFQDWEKQDHISSITYTRYFIADYIQEDKVLYLD
                     SDLIVNTSLEKLFSICLEEKSLAAVKDTDGITFNAGVLLINNKKWRQEKLKERLIEQS
                     IVTMKEVEEGRFEHFNGDQTIFNQVLQDDWLELDKEFNLQVGHDVTAFYNKWENYFNE
                     LVPPSIIHFVSYRKPWTTLIANRYRDLWWEFHDLEWTKILQHHIGEFELTSSLDKEFS
                     CLTLTNSQDLEGIEELVTALPDVVFHIAAWTDMGDKLIKLAVYDNVRLHPQIVPPVLD
                     KLKKSTNLYLDINHGSADENFLKSLQEQEKTLLAFQSTQHGELGQIVFENGKVSFMID
                     TIKDFKKNGHLTCFRQLPSLTCLTFTASQDIEQLDYLAGQLPNVVFQVAAWTAMGPKL
                     YDLSNRYPNIQLYPAISRDKLDELKEKMDAYLDINLLTSTSDIVAEMAHLSKPILAFY
                     KSQNGNNGQRLYSSEHPERMLADLQKLITKDMLEKPLDIIQVKGIDETLDYIIEHNSS
                     LVRFGDGEINMLAGHSIPYQDYDEELVSIMRDIIGQESREDLVVCLPDAFTDRFRFTS
                     WAIPFWKDHMDHYMDFYRELCSDSWYGSTFVSRPYIDFEDKSQAKAQFEKLKSIWENR
                     DLLIVEGATSRSGVGNDLFDEANSIKRIICPSHSAFSRVHEIEQEIEKYAGGRLILCM
                     LGPTAKVLSYNLCQMGYQVLDVGHIDSEYEWMKMGAKTKVKFSHKHTAEYNFDQDIEF
                     IDDETYNSQIVARILN"
     gene            complement(39703..40713)
                     /locus_tag="VQ548_000583"
     CDS             complement(39703..40713)
                     /locus_tag="VQ548_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET2653488.1"
                     /translation="MKLHLTNLYGMAGDSTVILAQNAVQKIASQLGFREVGIYFYNIA
                     SDSPSEMNKRLDGIMASISIGDILVFQSPTWNGFEFDRLLFDKLKDMQVKIICFIHDV
                     VPLMFDSNYYLMKDYMYMYNLSDVLIVPSERMKTRLMEEGLTTKKILVQGMWDHPHDL
                     SLYTPAFKKELFFAGSLERFPDLQNWSQDTPLRVFSNKGEASSSARNLSIEGWKKDEE
                     LLLELSKGGFGLVWGTYQNDGESNQYYTLNISHKVSTYLTAGIPVIVPSSLSTAKFIV
                     DQGLGFVANSLEEVHAIVDKMNLQEYQEMTNRIKTFSYLLKEGYFTKKLLVDAIYHLG
                     VE"
     gene            complement(40742..41617)
                     /locus_tag="VQ548_000584"
     CDS             complement(40742..41617)
                     /locus_tag="VQ548_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2653489.1"
                     /translation="MENELISIVVPIYNVENYLRQCLDSIQKQTYPNFECIMVNDGSP
                     DHSSKICEEFVEKDSRFKYFEKANGGLSSARNLGIECSGGAYITFVDSDDWLEHDALD
                     RLYGALKKENADISIGRYNSYDETRYVYMTYVTDPDDSLEVIEGKAIMDREGVEEVRN
                     GNWTVAVLKLFKRELLQDLPFPIGKIAEDTYWTWKVLLRASRIVYLNRCVYWYRVGLS
                     DTLSNTWSEKRMYDEIGAREEKIAILASSDYDLTNHILIYKNRLQRVIAKLEEQNMQF
                     TEIYRRMMEKLSLLP"
     gene            complement(41657..42535)
                     /locus_tag="VQ548_000585"
     CDS             complement(41657..42535)
                     /locus_tag="VQ548_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolysaccharide biosynthesis protein"
                     /protein_id="HET2653490.1"
                     /translation="MKKNHLVGDALILTVSDQIEELDYLLESLPNICFYIAAPVQFSE
                     KIRSLETNYNVRLRTITNEEQLNFLVDTCDFLLDINHFQEVDAIVSKFVQAGKSVFAF
                     DNTVHGNQGQEVFLSSTPDKLVSRVRDYLNEVRVGTNHQEKIIQDGTWNVFKIDDKAH
                     FIVGANVICRNFENFHVSSGKLILHDGVFINNSCSFNCMERIEIGAGTMMGEGVRFYD
                     HDHIYTAEKIEKWQWTTAPIRVGRDCWIGSNVTILKGVTIGDNTIIGAGCLIRNDIPS
                     NSVVYNNGNLVVKRRD"
     gene            complement(42532..44617)
                     /locus_tag="VQ548_000586"
                     /pseudo
     CDS             complement(42532..44617)
                     /locus_tag="VQ548_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000341103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
     gene            complement(44678..>45799)
                     /locus_tag="VQ548_000587"
     CDS             complement(44678..>45799)
                     /locus_tag="VQ548_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2653491.1"
                     /translation="STSASASASTSASESASTSASTSASASASTSASASASTSASTST
                     STSASTSASTSASTSASTSASTSASESASTSASTSASTSASASASISASESASTSASA
                     SASTSASASASTSASESASTSASASASTSTSASESASTSASASASTSASASASTSASA
                     SASTSASESASTSTSASESASTSASASASTSASASASTSASASASTSASASASTSASA
                     SASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASA
                     STSASASASTSASESASTSASESASTSASASASTSVSNSANHSNSQVGNASGSTGKSQ
                     KELPNTGTESSIGSVLLGVLAAVTGIGLVAKRRKRDEEE"
BASE COUNT        13348 a        10286 c         8210 g        13955 t
ORIGIN      
        1 attcgctaat tgtttttttt agggcgattg atttttactt ccgtcgcatc aatcattacc
       61 gtgtcttcag aactgagagg agttcttgaa atcgtaacac cacctttgaa caagagttac
      121 ttcaacccat tggctccgac ggagtaagtt gctttcgtgg ataccaaaat cagccgcaat
      181 ttcttcataa gtgcggtatt ctcgcacata tagaaagcgt tgttaattta tttatctcat
      241 ttttcagaaa attcttttat ttctgtaaag tctacgatac tcgatgtgtt tttatataat
      301 gatacagtct gagaatcact gttccgctag ccattccaat agagattacc aaagccaaca
      361 tgacaaccaa ggtcgcactt gccagtgctt tattatagtc ccctgtcaca aaaaaggcag
      421 ttgttcggta ggagagataa cctggaacca gcggtgccaa aatggccaag ataaagacca
      481 cagcaggtgt cttataaaga atacttaaaa tctggctgac acaagaacca ataatggctg
      541 caatgaaggt agctacaatg acattggtcg gttccttgag caagagatag attagccaga
      601 cagtcatgcc caaaatccct ccaggtaaga gcatagaccg ttgcacattg agtacgatta
      661 aaaaagtgat aatggcaaga aaacttgcta ctgcttgtaa taaaaaggtt gttagtgtca
      721 tattagttca tcaataccaa ggcgacagaa gttcctgccc ctaaagcgag ggtaatgagc
      781 agggattcaa acatcttact cataccagag tttatgtggt tggtcataat atcacggacc
      841 gcattggtca aggcaatacc tggtacaaac ggcatgaccg caccagctat aatcaaatct
      901 gccgttgaag gaaaacctgt gtagcgagcc caaaactggg caattatccc aaagacaaag
      961 gctccagcaa aggctgtcac aaagggaatt cggataaatt tttccacata gagggaaaag
     1021 gcaaaaccaa ataaggtcgc cactcctgcc ccaagtgcgt cgtagatatt tccgctaaac
     1081 ataactgaaa agaaaggagc actaaaggtc gcagccagag ttacctgcaa cttagtatag
     1141 ggaaggggtt gagcttgcaa ggccgtcaat tgcttaaagg ctgtttctaa gtcaatctgc
     1201 cccccaacta gctgacgaga aatctggttc acatcgcaga ctttttcgat gttataagaa
     1261 gaggaggtca cgcgcttcat gcgcgaaata ttggtatttt caatagagaa aaagatagcg
     1321 gcaggcatgg caaggacatt gcaatccaca atcccctgcg aatgcgcgat tcgaatcatg
     1381 gtatcttcta cacgatggat ttctgagcca cttttaagga gaatagtccc cgctagcata
     1441 atcacatcaa tgacggcatt taattctttt gattcttcca tgctttcctc cttttatcaa
     1501 ctccctctat tctatcacaa atccggactc aaaaaaaatc tttgccatga aatcatgaca
     1561 aagattgatt actcattttg attatccatc tgcttttaag gagtagctga agttgtttta
     1621 ggtttgtaga ttgaaatctt gactctagtc ttattgaggt ctaccttttc acctgctcta
     1681 ggactttgtt caacaaccat gccttctaca ctacctgcag gcgctgtcgt cacttctaca
     1741 acttctatat tagcttcctt aatcccaaca atttgaatca aattgttctt agtaaactcc
     1801 aagctggaac caatgtaact cggcatggca acacttgtaa cttttttagc tactgtcaag
     1861 acaatttgag taggtttact cacatcataa gtcgttccgg cacctggact ttgtttcata
     1921 atcgttcctg gttcgctttc gctggactct tcttcctcta tcttaatcaa attctcagga
     1981 accttcttct gcttgagttc tgagattact tctgtagagt tccgtccaat atagttccct
     2041 aattgaatcg tcgtagcttt tttagctact gtcaaaacaa tttgagttgc cttgctcaag
     2101 tcataggtcg taccttctgg tagactttgc ttcaggaccg ttccagcctc actctcattc
     2161 gactcttctt cctcaatttt aatcaaatta tctggaactt ttttctcttt taattccgcg
     2221 ataacatcag aagatttccg gccgacataa ttactaattt ggaaggattg tttgcctgat
     2281 gagacaacca gattgatttt cgttccttct tttcgaccag ttccagcgcc aggatctgta
     2341 cggataatcc gcccttcttc caccttttca ctagcctctg tcttctcctc accaatctca
     2401 aaattggctt ttttgagcgt tgccttggcc tctgcaactg tctgacctgc cacatctgga
     2461 atggcaatgg ttgcaggagt tctggatagt atccaaataa gagaagctgc caccaataca
     2521 aggctggcca acaaaatcag gtaacgcatc ttaaatctat gttttttcgg tgcttgtggt
     2581 tggtaagttt cctctgtcac agcctggctt gggtttttga ttgatttgtg ttctgtctgc
     2641 gcttgaacct taggaataga tgtcaaggta ctctgagaaa ccttcggcaa ggtcttggta
     2701 tctgccttgc tcgtttcatc aaagattaac ttactttcat ttctacgatt gtaggacaag
     2761 ctactagaca agtccacata catctctgaa accgagcggt agcgattggt caacttttta
     2821 gcagttgcct tgataataac attttctaaa gcctgaggta cagatggatt ttctgcaata
     2881 acggacggca ggggtttctg gaaatgctgg agggcaatgg tcaccgcgct atccccgtca
     2941 taagggatat ggcctgtcaa catctcatag aaaataatcc ccatggcata gatatcactc
     3001 tgcacagtcg ccttcgaacc acgcgcctgc tctggtgaca agtaatgaac tgagcccaac
     3061 atcgagttag tctgggtcag acttgtctct gcaaaggcta cagcaatccc aaagtctgtg
     3121 accttggcag tcccatctgg tgtcaaaagg atattttgag gtttcaagtc cctgtgaaca
     3181 attcctcgag tatgggccaa gcgcatagcc aagagaattt gtcccatgat acggactgct
     3241 tcttcattag aaagaggata atgttccttg atatagcgtt tgaggtccag tccagccaca
     3301 tactccatag ctaggtactg ttgaccgtct tcctcgccaa tatctgttat ccgaacgata
     3361 tgaggatggt ctagatctgc catagctctc gcttcacgct gaaaacgagc tacagctatc
     3421 gggtccgtct ggtagttggt cctcagaacc ttcactgcca cttcttcccc atctaagatt
     3481 aagtctttgg ctaggtagac atccgccatg cctcctcgac caatctgttt gacaatccga
     3541 tagcgtccgg caaaaatctt gccgatttgg atcattctgc atcctcctcg ttcataaaaa
     3601 caagggcaac cgtaatgttg tctaaacctc ctgcattgtt agcaaaacga acaagtgtct
     3661 ccgttttatc tgctaaagga atatcactgg ttacaatatc acgaatctca ctgcctgaaa
     3721 tcatgttggt caagccgtca ctattgagca agagatagtc acctgactca aggataactg
     3781 tcccaaaatc aggctgaatt tcatcttttt gcccaataga ctgggtgata atattttttt
     3841 gcggatgagc ttctgcctct tctggtgtca attgaccagc cttgagcaat tcattaacca
     3901 aggaatgatc gctcgtcaac tgatggtatt cttctccacg aatcaagccg atacgcgaat
     3961 caccaatatg agcatagata gcctgattat caataatagc aaggacttcc aaagtagttc
     4021 ccatgcctct gtaagcttca tcctgaccaa gctggtgaat cttttgattt tcaatttcta
     4081 ggtaatgggc gaaccattca cgcacttcat tgactgtatc gatctgggta tcaacccaag
     4141 ctacacccag gtctgtgacc gccatttcac tagcgatatt ccctgcacga tgacctccca
     4201 tcccatcagc taaaataatc atggtacgtc cagctctatt gacatagtgg ttgacatagt
     4261 cttggttatt tgttcgtttc tgaccaacat ctgttaataa tgaaatttcc atgtgtcagt
     4321 tccttcctaa tccgatatct tgcgaaattg actgatgaag aatccatcac ttccatacaa
     4381 ttcaggtgta atgaggatac agccgtcttt catgatatcc ttacattcat gttctagttt
     4441 tacctgctcg aactcgggat gactctctaa aaaggcctta acgacttgaa aattctcctc
     4501 tgagacgata gtgcaggtgc tataagttat tataccacct ttgcctagta tttgacaaac
     4561 actacctaat atttctaact gaatttcctg caaggacgcg aaatctgccg tttctttatt
     4621 gtatttgata tctggttttc ggcgcaaaag accgattcct gaacaaggag catccaccaa
     4681 aatcttatca aaggaatcct ggtcaaaaaa ctcatgcacc tttctggcat ccaatttttg
     4741 agtttgaacc cgatcttcaa ctcccagacg ttgggcattt tcttgaatta aatccaactt
     4801 gtggtcgtac aagtccagag cagtaacctg acctgtcgta agataagagg ctatatgggc
     4861 tgttttccca cctggagccg cacaggcatc aagcactcgc tcatcacctt gtaaatcaag
     4921 cgtcggagca accaactgac tggactcgtc ttggatggta atggctccat ccgcaaacaa
     4981 attatgccct gcaaaatgcc cctgctcctt aaccagacca gtggttgcta aaagggaatt
     5041 attcgcctcc aacaaggctt ggatttcctc ttttcgactt aggtctgtta cacgaatact
     5101 ggctttgttt cgcactaaca ggctttcaaa gatggctttt gctctctcct ctccgtattc
     5161 ttccttgagt ttggcaacta gccaaactgg gagagaatag gcaatggagt cacgcttgtt
     5221 ttttcgcttg atgctagcaa tatctggcca gccttcacgc aagatacggc gaaggacagc
     5281 gttgaccaat ttttcactgc cttttttacg gagtttggcc aattccactg cttcattgac
     5341 cacagcatga tctggaatct tgtccaaata gcggagttgg taggcactca tgagaagaag
     5401 gacatagagc cagctgtcta actggtctct gtcttcgata aagtgggata ggtaccattc
     5461 cagagtcagt ttacgggcta ccgttccata gactagctcg gtcactaagc ccttgtctgc
     5521 tgcagagagc tgactcccct tgaggtgttt atttaaggca atatttgaat atgcttgatt
     5581 cacaaaaaca tcctctagca ctgctagagc taaacttcta gccgtttcta ctttagtcac
     5641 caaatcgttc tcctacagtc aatgtacgtc caactccatt gaggaaggaa gcaatgtcca
     5701 tcttaggctt accagctggc tgcacttgtt tgagggatag agccccttca gccgttgcga
     5761 caatcaattc tttcttgccg atagagagaa tctcacctgg atttccctga ccttctactg
     5821 gtagggcttc ataaatctta aagcggtcgc ccttaaggaa agtatgggca acaggccagg
     5881 ggttcattcc acgaatttgg ttaaagagtt gacgattggt tttgttccag tccagttttt
     5941 cttcctctgg ctttatattt ggagagaagg taacctgact cgtatcctgc ggttcaggtt
     6001 tgatatcacc agcaatatag gcaggcagag tgtccaaaag caaatcacga ccaactagcg
     6061 ccaatttttc aaacaaggtg ccaacattgt cctcatctgt gatcggaatg ctgcgacgag
     6121 aaatcatatc tcctgcatcc atttccttaa ccatttccat gatggtcaca ccagcttcct
     6181 catccccttg aatcaaggca taatggatag gcgcaccacc acggtgtcta ggaaggaggg
     6241 aggcatgaac gttgacagca aagtccatgc tatcaaggag tttgcttggg agaaactgcc
     6301 caaaagcagc agtcacaatt ccatctgctc ctagcttcat aagttcttcc atctctggac
     6361 ttccagataa tttttcaggt tggtagatag atagtcctgc ttccttggca gcctgcttga
     6421 ctggggtttc ttggataact tttttacgac caacagcacg gtctggctgg gtcacaacgg
     6481 ctagaatttc gtaacggtca tctgtcaaaa gtccttttaa gactgttgct gaaaagtcgg
     6541 gggtccccat aaagattagt tttgtcatat cttctccttc ttataaaaat tgctgcggct
     6601 catggtcaat gctgagacgg agctcactat tttcccgttc ttgagtcaag gccaagacct
     6661 ggttgagggt cggccccagc tcatcttcta aacggtattt aattaaaatc tggtaatgat
     6721 agaggttgtg ggtacgggca atcggttttg gcgttggccc cagaatggga ctggtctctg
     6781 acaagcctga ccgcaaaatg ttcatgactt cataggcacg tttgaaaacc tcttcttctt
     6841 tcttgtgaga aagggtaata ccaatcgtga aatagtaagg tggatagccg agttgtcgtc
     6901 tgattcccat ttcataggca taaaagcctt cgtaatcttg atccttggca aatcgaatag
     6961 catagtgctg cgaattgtag gactgtatca agacttgacc tgctttttca gcccgacctg
     7021 ctcgacctgc cacctgagtc aagagctgga aggttctctc agaagaacgg aaatcaggca
     7081 gattcaaggc cgtatccgca tttagaactc cgactagggt aacattggga aaatccaaac
     7141 cctttgcaat catctgagta ccaagtaaaa tatccgcttc ccctcgccca aactggtcaa
     7201 gcaaggcttg gtgactgcct ttctttcgag tcgtatccac atccatcctc aaaatgcgag
     7261 cttggggaaa gagttctgct agctcatcat aagccttctg agttcccgtc ccatagtaac
     7321 gaatactgcg gctcttacag ttaggacaga cctgaggaat atccttcgag aaaccacaat
     7381 aatggcagtt catagtcttg gtatccatat gcaaggtcag agaaatatcg cagttgggac
     7441 aagtatccac cgtcccacac tcccgacaca tgacaaagct agaataacca cggcgattga
     7501 gcatgagaac cacctgctct tttttaacca gacggtcttg gatagcctct agcaaaggag
     7561 gcgtaaagtt tgacgtctca ttttgtccga tatagtctcg aaagtcaatc acttgaacct
     7621 cagggattgt agccaaagga ttggcacgtt gggttagacg taagtgttga tagacgcctt
     7681 tgccagcacg tgcccggctc tctaagctcg gcgttgcaga tccaagtacc agagttgctt
     7741 gattatactg agcccgtaaa atagctacct ctctggcatg gtaacgggga ttgctgtcct
     7801 gcttataagc cgcttcatgc tcttcatcaa taatcatgac acccagattt ttcagaggag
     7861 caaagatagc agatctggca ccaacaacaa cttgggcatc gccacgctcc accttgcgcc
     7921 attcatcata cttttcgcca ttggataatc ctgagtgaag aatggctacc ttgtccccaa
     7981 aacgtgctat aaaacgctcg gtcatctgag gagtcaagga aatctcaggt accagcaaaa
     8041 tagctgtctt acccttatcc agggcacctt ggataatctg caagtaaacc tcggtcttcc
     8101 cacttcctgt aatcccttga agtagaaagg gaggttgaga actgccaata gaactcacaa
     8161 ccgcatcacg cgcctgtctt tgttctggat ttaactccaa aggtctactt gcttcaattc
     8221 cttcaaaata agcagccgag cgttgaactt ccttttggac tatggtaaca gtaccttgat
     8281 ccacaaagaa gttgacttgc tctcgcgagt aggactctaa caagctagcc aaggaagcgc
     8341 tctctggatg agacagcaga taatctctca gttccaactt tttcttggca cgtgtagaaa
     8401 tctcaacacc ttctaattgg gcatggtcaa cctcatacca agactgggtc ttgaccttct
     8461 tttgatcgac tgcctgatat tccagaccaa gcaggccttt tctagtcaaa cgcatcattt
     8521 cagcttgctt ggcaaggtct agtgaagaaa aggctagcga atcttctgaa ccaaacaggc
     8581 gtactcgttc ttcctgactc aagccttcca gaggatagag aatcttgtca tagctagaat
     8641 tcagaaaccc tggaagcatg gccttgagga tagagatttt gtaggagaag acagatttgc
     8701 gtaactcctc agccagccag agttgttctg gcgtgagaac aggagaaaaa tccagcacct
     8761 ctgcaatatc ttttaaatct tgctccatct cttctccatc tgattgggac ttcaaaccaa
     8821 gaacaatccc ttgaatcagg cgattaccct taccaaaagg cacatgaacc cgcatcccaa
     8881 cttccagcat tccctcaaat tcctccggaa tcctgtaact atagggctgg tccgtctgca
     8941 tcaagggcac atctacgata atcttagcta gggccatctt ctcacctcct ccttgtcagt
     9001 acattcttgc aatagaaaaa ataagattga gtccccccaa ccttaaattt tttcaccatc
     9061 ttctttttct ttagcaattt gctctttgat tttcttttct tcttcttctt tgcggcgttt
     9121 ttcttcttcg atacggcgac gcactgcttc acgttttcct tctggatctg ggtgaattgt
     9181 aacgtttcct gattcgattt cttctaaagc gcgaagagtt gatttttcag acttgaaacc
     9241 ttgagttgct ggggcacctg cttccaattc gtgggcacgt tttgcttcca agattacgag
     9301 tgaatatttt gaaggaacct tgtcgagcaa ggtatcaata gagggtttta acatcatttg
     9361 cttgtaccta ttttctaaat tttatcgggt agttggagat tttggtaaca tctcctgata
     9421 gtgaccaatg acacgatcca cacagaagtg ttctgcttca atcacacatt tgacacgttc
     9481 agcagctagg ggcacctgat cgttgacaat cgcataatca tactcacgca tgagggcaat
     9541 ttcttccttg gccttttcga ttcgttgggc aatcacttct gcactatctg ttccacgacc
     9601 taccaagcga tcttgcaatt catccaaatc tggtggtgtc aggaagataa agacagcatc
     9661 tggaaccttt ttcttgacct gaagagcacc ctgaacttca atttcaagga aaacatcgat
     9721 tcccttgtcc aaggtttcat tgacataggt cagaggagtt ccatagtagt tgccgacata
     9781 ttctgcgtat tccaacatct gtccttgacg aatcagctct tcaaattctt cacgagtacg
     9841 gaagaaatag tcaacaccgt ccacttctcc aggacgttgt gcgcgtgtcg tcatcgatac
     9901 agaatattga aattggtttt cagaactctc aaaaatctct cttctaaccg ttccttttcc
     9961 aacccctgaa ggaccagaaa aaacgattag taagcctcgg tctgccattg tgtctccttt
    10021 tagtcaatct gtgaaataac atttctctag aataatggca aaaagccaga ttatccttta
    10081 cagtctttct atctagtgta acaaaaaagc agtaattttt caactgctct ttcttattta
    10141 tttagcataa tctactgcac gaagctcgcg aatcacggtt accttgatat ttcctggata
    10201 atcgagattg ttttcaattt tcttacgaac tttgtgagcc aagattgtga ctttgtcgtc
    10261 cttgattttt cctggattga ccatgatacg aatttcacgt cctgcttgaa gggcaaagct
    10321 agtttgcact ccttcaaagc cgttagcaat ttcttccaaa tcatggagac gcttgatgta
    10381 gctttcaaga gactcactac gagcacctgg acgggctgcg ctcaaggcat ctgctgcagc
    10441 gacgataact gctatcacgc tctcagcttc aacatctccg tggtgactag caatcgtatt
    10501 caccacaact gggggttcct tgtacttacg ggccaattcc ataccgattt caacgtggct
    10561 accttcaacc tcatggtcaa tggctttccc gatatcgtga aggaatccag cacgacgggc
    10621 aagagccgca ttttcaccaa gttcgctcgc catgatacca gccaacttag caacctcaat
    10681 cgaatggcgc aaaacatttt gtccatatga agtacggaac tgcaaacgtc ccataatctt
    10741 catcaagtct ggatgaaggt ttggcgcacc aatttcatag gcagcagcct caccgtattc
    10801 acgaatctta ttgtcaatct cttgacggtt tttctcaacc aactcttcga tacgagctgg
    10861 atgtatacga ccatctttga gcaacatttc catagtcata cgggcaatct cacgacgaat
    10921 cggatcaaat cctgacaagg tcaccacttc tggtgtatcg tcgataatca catcgacccc
    10981 tgtcaaactt tcaaaggtac gaatgttacg accttcacga ccaataatgc gtcccttcat
    11041 agtatcgtct ggcagatgaa ctgttgagtt tgttgactcc gctacatatt caccagcgat
    11101 acgttgcata gcttgaacca agatgtcctt ggccattttg tcagaacgtt ccttgacctc
    11161 ttgctcagct tcgcgaatgc gactggcaat ctccctggtc aagttttcct ctgtctgagc
    11221 caagataata tctcgtgctt ctgcctgaga cagagcacca atacgctcta gttctgcttc
    11281 tttttgtctt tcgacttcct ctaattgctc ttcacgcgca tcaaggtttt tcgctctatc
    11341 agaaatactt tgttcttttt gttcaagtgt ttgttcttta ctcgtcaaat tgtcgtcctt
    11401 acggtcaagg ctagtagctc tctctgtcaa acgactttcg atttgtttga gttcttgacg
    11461 ttctgatttg aattcagcgt ccacttcttc acggtatttt ctggcttctt ctttggcctc
    11521 caatagtgct tcttttttaa gagacttgct ttcacgtttg gcttcattaa caagtaaatc
    11581 cgcttcacgc tcagcttgtc cacgtaaatt agttgcttct tgttcagcat ttaaaagcat
    11641 caactctgca gcttcctgag atgatttcat cttagctgag atgctgacat atccaatgac
    11701 taaaccaatg atgacggcaa aaacagcaat cgcaagcgac atgatttcca tgtttttacc
    11761 tcattttatt gttattccga atgacataca ttcttttaca ttctaccata aaaaagtgat
    11821 tttcacaaac ctaaaataga atatgttttg gggaatttgg aacacattta ccaaaataaa
    11881 cttgttgttt agaaatagta gtttagtaga gacttgagaa aaagcctact ttgcagtaga
    11941 cttagtaatg atctttaaag gacaagaaag ccacgctatc tccatccatc atataaatca
    12001 agcgattttc tgcatcaata cgccgtgacc aggctccttg gtaatcatat ttgagtggct
    12061 ctggttttcc tattcctgta aatggatcgc gttgaatatc cttgattaat ttattgattc
    12121 tttttagtgt ttttttatct tggttttgtc agtagcaata atctgcccag gcatcttctg
    12181 taaacttgag tagcattcat cactcctcaa tcacatggac ctgagtgctt ccagcacgga
    12241 cttgagccat tcctcgcaaa accttgtctg ataactcctt attttgggcg attctcaggg
    12301 tttcctgaat actgtcccat tcgctctttg aaagaactac aatgtcctca tctggatttt
    12361 tattgaccac cgtcaaaggc tcaaattcat catttacctt cttcatgtag tcctttaaat
    12421 gatttcggaa tgttgagtaa aggactgctt ccataaccat acctcgtttt agctcttttc
    12481 cactattata cacgaaaaga aagaaattgt caggaacttg tacaagattt tcttttctat
    12541 ctatttatac tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gctgtacttg
    12601 agtacggcaa ggcgacgttg acgcgatttg aatttgattt tcgaagagta ttattcgtaa
    12661 aaaatctcaa aaagcctacc tttcggtaga cttagtttgt ttctattcta atcggcactc
    12721 ttccaaaatt ttgctctgct atacttggct tccctagttg gtaaatctgg tctgcttttt
    12781 gggtcatagc atcccaaggt tctttgccaa ttcggctgac tagattgacc tgtcctttca
    12841 gagacttgag atgttgcctg actttttcag taaatccaag gacatgaatg gcttctggca
    12901 agacattttc tctagcctgt accaaaatat aggtcaatag gcgtctgaca cgcgccttgg
    12961 tgtaacgttt ggtagtcact aactcgacca attcttccac agactgggct gttttaatag
    13021 cttctttaat gcgcacagcc atttcttgat tgacctgata gatggtggtt aggtcgggat
    13081 ttgacaagat ttgatagcgg agcaagggaa aatagtcttc ccagatcacc ttactggcct
    13141 gctcaaatag ggcaacagaa ggcataaaac gttctaagaa atcttggtcc ttctgatgtt
    13201 gacggagggc tgtcgccgag gcaaagtcca catctttatt cacagaatgg taacctgccc
    13261 cctgacgctg aatcggatgc agcttgatat ttcgtcctgc aaccgccttg gcataggcca
    13321 gagcaagaac atgattgggg gtattacctg aaaaatcaag accagcaaat tccttccaca
    13381 tagcttgggt tttctgggga taggaaaggg aatcaggcag atttttcaca aatttctcca
    13441 tctcagcacc tttctctgtg tataagtcag cgattttctg gtaatccaga acttcctctg
    13501 tcccaaaaac tagactatca atgcccaagc gatccaagat atccacagct ccttgaccaa
    13561 agaaatcagc tgcctgaaca ctgactaaaa agggcaattc cactaccaag tctgcgccat
    13621 tttccagcgc catctgggcc cttgtccact tatccacaat agcaggctct ccacgctgca
    13681 tgaaattccc tgacatggca acaattttca gtccctctgc ctgatccagc aggtatttat
    13741 ggccattatg aaaaggattg aactccgcga taatacctgt tatggtcatg ctaatctcct
    13801 acttctgcgc cacaaaaaac caacgggtgc tagtttctgt tggctcctta tcctcaaagt
    13861 ctgcatagag tttgaaggac ttaaatccag cctgttccag caagatatca taggtcaaga
    13921 tctcataggt cctctcctca tgtacttcat cgtggcgact aaaggaaccg tcagcctcct
    13981 tgataaagaa agtcagctca tgcacgatgg agtgaggaac ttcgtcctca tatgtatccc
    14041 aaagcatggc aaaatcttcc gcattttcat ggtaggaata gccagggaat acttcatctg
    14101 tctggtaggt cgagtgcacg tcaaagatga aaactccctc ttcattcagc gcattgtaca
    14161 cgtccttaaa gacgtcccct acttccacct catcctgcat atagcagata gagtccgaat
    14221 aacacgtgac aaaatcgtat ttccctgcct tggacaaatt cagcatatta ccttctataa
    14281 aagcaatctt ttgcttggct gaagttgctc tcttctccgc aatcttcaac atatccgcac
    14341 tcaagtcaag tccagtcaca tcaaaaccag cctgagaaaa gcgcactgat tgaattcctg
    14401 tcccacaagc caattccaag agtttctttc tctccttggt cttaggcaaa tgacgcagag
    14461 aaaaattcgt ccatttgtcg tataaactat cgtccatgac cgcatcatag accgccgcaa
    14521 aggtttcata agtcgccata aaacatgata ccaagtccgc ccgtaattcg atagaaaatt
    14581 aggagcctta cgatggagcc gagctccaag gaaggctatc tattttccga gaattacagg
    14641 acgggttcaa atcctttcta agatacaaag agccttaaaa gcaaagagta cataggaaac
    14701 tttcttccct atcgtcagat acaaagaaag ttacttttta tctcagcttt tagctcgtgt
    14761 tcagtttcga aatgaaacaa acacgaggcc ctttaccttt ctatcaattt ttctaaaata
    14821 agcaaagaaa cccagttgac tacaactgag ttcatcttct aagcaagagc ttctgaaata
    14881 tctactgaat tcgcctcatg ccatagcttc tctagattat aatgggcacg catttcttct
    14941 gaaaagatat gcacgacaac agcaccaagg tccagtaaga cccagcctcc agctgcatcg
    15001 ccttcgacat ggctaccttt aaagcctgct tgagctactt tttcacggat attagctgcg
    15061 atagcgtcca actgacggct attcattgag ctagtgatga caaagtagtc cgtcacacta
    15121 gtcaaatctt gtacatcaag tgcgaggata tcctccgcac gtttctcatc agccgctttc
    15181 acgactagtt ctagtaattc tttttcgttc atttaatcct ctttttagaa aatatgtttg
    15241 taatctagaa catctgcaaa gcgctcctcc caaatgtcct cataaaattc attaatcgtt
    15301 tctgctggaa tgtcatcccc atcaaaggtt gtgacagcac cttctggaac aataagctga
    15361 tagccatatt caaaggcaac cttgacagag gtatccacac aatattctgt ctgcatacca
    15421 cataaaacta atttttcaat cccctgctta tccaagtatt cttttaagcc agtttctttg
    15481 aaaatactgt tatacttctt ctgaaagacc ttttcagcag gttttcgatt taaaagcgca
    15541 gataactgcc aatcttctga tgtttgagct tcagagttct caatatgttg aacatagata
    15601 atttcaatat tcttgcttct agcctggttt tgtaaataag aaatttttcc caatagactt
    15661 tttgtctgga acccagtttc tactaaaata ttctgaacat caatgattat aaaagccgtc
    15721 ttcatttagt tctctttcaa atagtgcaca aaggcgttat aggtttcaag ggtttgggga
    15781 tagatgggga atccctgatg agctagatac tccacggtac gagctgtttc gtaggccacc
    15841 gccttattga gcgatagatt tgcaatctca cgcgccacat ctactccagg aaaggctcga
    15901 ttgtgctcga tatagtctgc gacgtagatg accttatcta ggtctgtcat ttgaccagca
    15961 ccgactgtat ggacttcaat ggctcgcagg atttctgaat catgcaaatc caaatcttcc
    16021 tgaattttgt aaattccgac cataccatgc cagacattat tgccccagtt tttgaggtca
    16081 gggtctagct ggtaacggtc aatcaaggct agaaattcct gatttgacaa ctttttagca
    16141 tagtcatgaa gaagacctgc tagacttgct ttctcaacat ctacaccaaa gcgctgagct
    16201 aattccatag cggcacgctc cacacctaga caatgggtta gacgtttctc aggtagaaac
    16261 tctgccattt tttccaacaa ggcctcacgg gagcagttga tatagtcttg ataggacatc
    16321 agtagagccc ctccttctcg atgtagtcta gcactggctg aggtaggaga aagttgggtt
    16381 tccgaccttg ggcaaggaag tcccgcacca tgctggacga gatatccatg agcggtacgt
    16441 ccacccagat aactggatag gaagtcccta ccttgtagcg tggacgctga acccccacaa
    16501 actgaaccat gtcaaccagt tcatcaattc ggtaccactt aggcagatag tcaaccatgt
    16561 cggcaccgat gataaagtaa taatccgtat ctggattctt ctctgtcaaa atcttcatgg
    16621 tgtcgtaggt gtaggaaata cccttgcgct ccaactcaat ggtttcaatg actaggccgt
    16681 caattccctc aattgccaac tcaagcatct tgagacgatg gtgttcaggg atggtttcct
    16741 ttttatcaac gtgaggaggt tggtattcag gcatgagaag aacttgatcc agtcccaact
    16801 gttgccgtac ttgatccgca acaatgagat gggcattgtg aacagggtta aaattccccc
    16861 ctaaaatccc aacttgtttg cgttttttct ccttgatttc tggctccaac tctaccttgg
    16921 taaagggagt caatagttcg attgtcatag gctagtcccc tttatttctc tataaaaaca
    16981 gttatttgga gtttcggtct tagatttctt tgactttctt agaaatcttg cgattttctt
    17041 tcttgctaga ttgcttaaac aaaatcaaga tgcgtcctat tttttggact gtatccacac
    17101 cgatttcttc ttccaaaatt tcagctactt cgtggatgtt ttcatctgtg ttttgtaaga
    17161 gagtaacctt gattaattca cgcgcatcaa gagcttgacg gacgctggtt ttgatttggt
    17221 cgttgagtcc atttttcccg atttggatga taggtttgag ggtgtgtgcc tggctgttga
    17281 ggaaggcacg ttgttttgat gctaatgaca taattttctt ccttgttttt tgatagttat
    17341 tttaggtggt gagggacggt cggaactaat tttccaaaga tttcatcttt gaaaaatgga
    17401 tttcctgacc tcacaattga gccttggtct caattgtgcc ccttgccaat ctacagattg
    17461 gcaatcacac cacggcaata actatcgcta tatgagctca ctttgttcgc tcagcgattt
    17521 tgttttaaat aattgctttt cgtgtggcga cggcgacgcc ttctggtgcc cagacggcga
    17581 cttttgctgt gcctgttaca cgaatccagc ctaggcctga aatgactagg tctgtcttat
    17641 ctttaatggt aaagacatgc tggactagcc ttgggaaatc ttctttttcc ttgctatttg
    17701 gtggtgtcag aagagttccc aggtgcttat cgtagaaagc actagctcct tcaagcttgc
    17761 tacgatggag tttgagttca ttatcaaaga aagcagtaaa tccttgcttt tctcctgcta
    17821 taaagtcaaa gcgtcccaaa ccacctaaaa atagggtttg ctcaggatta agctgatagg
    17881 tcttaggctt gatttccttt ttaggactga catacttgag gtttttggcc gtcaagtagt
    17941 gagccatctg gtggcggtgg ataattcccg gcgtatcgta aatataagat ccgtcgtcaa
    18001 gcggaatctc tattttgtcc aaggttgtcc ctgggaagcg tgaagtagtg atgacattct
    18061 gatcacccgt gatttcttgg ataatagcat tgattagagt tgattttcca acgttggtca
    18121 caccgaccac atagacatcg cggcccttac ggtagtgttc aatcttatca atgacttcct
    18181 taatggcatg tttattttgt gctgaagtta ggaccacatc gactggacga agaccttctt
    18241 catgggcacg tttcatgagc cactggctaa tcttaccaga cttaactgac ttaggaagga
    18301 tatctttttt atttcctacc aagaggacat cattgcccga gacgaaacgt ggtaaacctg
    18361 ggatgacaga tccattaaaa tcaaagatat caatgacatt gaccactaag gcatcactgt
    18421 ctcccacctc gtgcaagagc ttgaggaaat catcgttcgt caactggaca tctgtgattt
    18481 cattgtagtg gcggagacgg aaacagcgtt ggcaatagac ttcgccagtc tccaaacctt
    18541 tttcaagtgc cgactggggg gtaaaaccaa gaccagcttt atctgtcgtc tgaatggttg
    18601 ctccacaacc aatacagaga atttcttcca tagttaaatt ccttttttat atgtaatcgg
    18661 tccgtacttt tcagtgattt ttctcataac acgacgctca cgagttcggt taatctgcgt
    18721 tttgattgag tcatgttgga ccaagggttt gactaaaatt gaccgaatcc ctgcacggtg
    18781 ggctgctcgt atatctgtca tgagctggtc gccaaccatg accacttcct ttttgtcata
    18841 gtggaattcc ttcatggcac ggtcaatacc aaatgtgaag ggcttcaagg cccagtaaac
    18901 gtaatcaatc ccaaatttct caactgctcg ttgaacgcgt tttttggtgt tatttgacac
    18961 tacgataatg ccaatacccg cgtcccgaag gtcatgtagc cattgcttca tctctggcgt
    19021 tccatcaggg ttgttccaag caatgagggt attatccaaa tcgaccaaaa cagccttgat
    19081 tccctgcgcc tgcaggcttg ggactgtcag atcatagact gcttccacag caaaatctgg
    19141 tatataattt tcaatcgcca ttctggctcc ttttcttaac tttttttcgc aattttcctt
    19201 agtaacaagg ataaaacaat ccacaaacct gcactagcca aactgatata gagccaagca
    19261 tggggctcat ctgttaaagg taagggaaca ttcattccga aaaagcctgt cacgactgcc
    19321 aaaacagcta gcaagactga aatgatagtc aaggttgtca aattgtcatt cagattattg
    19381 tttagaatat tgttgtaaga ggctgaaagc tgctgtaaaa tctgagagat taggtctgtc
    19441 atggatacca gctgatgagc ctcaatcatg gcatcatcaa actgttctct ctcaatctca
    19501 tcaaaactac gatacaaggc atgaccttga atatgctcta acaaaatccg attttgtttg
    19561 gcagctgccg tcagataaac cataccagtc tccaaatcag acagggcaaa gaggtttttc
    19621 ttggtagttc gctggcgcaa gaggtcattg acctcatccc tactcttgtc catctgctca
    19681 atgacaggat agtaggcatt gctgatgatt tccagactgg caaagagaaa cttataaatc
    19741 gaaagcgtgt catggctctc cagataacga gtcatctgtt caatgacata ggcgttcttg
    19801 gtattactaa tggtaatcag gcgacgatgc tcgacgataa aggtcatggg aaaagtctca
    19861 tagtaggcct tgtccttttt tacgtctagg acattataga taaaggtaac cgtcccactt
    19921 tcacggtggt agtccatgtg ggcgcgctcg tttctatcca gtgcgtattc aatggtttcc
    19981 ttgtccaaac cgtaaatttc agaaaggtct tctagtttat tcaactttcc taggtctagg
    20041 tctatccagg tacaaccatg gcccaactgc ttttctaaaa ccatcttttc tccttattaa
    20101 actccctcta ttgtaccaca aattacttaa aataacaggt ctagtctgtg cgtgagaaat
    20161 tgctaacaac tgtgatattt cggttaggga caaagtgaag ggcttgctcc tcgctacgaa
    20221 gctgtgtcgt acgaattccc acactgacaa ccttacccga tacagtaatc ggtccatttg
    20281 tcagaacgac ctcatctccc acatccagtt gacgttcaaa gaggatgaaa aagccattga
    20341 tgacatcaga cagaaagcct tgggctccca taccaatcgc taccccagca ataccagctc
    20401 cagccagcaa actagaaact ggcaaaccta aaatcgacaa aatgcagtag agtaaaaaga
    20461 aatatagcgt ataattaaac acattttcta gtaaacgtga gatggttttt tggcgtccga
    20521 catcatgacg agacattttt agagaaggtt tgacaattct ctgcaccatg gtatgaagca
    20581 tttttttagc aatataaaat acaatcaaaa gcagtaaaag agaaatgacc ttggttagaa
    20641 tattctcgat aatggttgtc acatctagct tttcaatata agcctgaata aatttttgca
    20701 tataaaactc ctttatttca ttataccata ttttcatcag tctcattctc cataaatatt
    20761 caaaaaatag acagaaaatt cttgattttg tctatcattt atactataat cataatcact
    20821 acacaaaaag gagattatta tgaaaagaat cattcatgct tggaataagg caagccttgt
    20881 caagcgtatc ttgattggta tgctttgtgg ggaatcctag gactgaccct tcctaatctc
    20941 tcagggattg ggctactcgg ggatttattc gttggaggtc taaaagctgt tgctcctatc
    21001 ctagtctttg ctctcgttgc caatgccctt tcccaacatc aaaagggaca agatagcaat
    21061 atgaaaactg ttgttttctt gtatatccta tgatagggac tttcgccgct gctcttgtag
    21121 ctgtactagc aagtttcatc gtccctattg aaattaccct aaatagtgcc aatactgaaa
    21181 ttgcaccacc agatgggatt gggcaggtcc tcagcaacct cttgctcaaa ctggttgaca
    21241 gcccagtcaa cgccctgctt actgctaact atattggaat cttatcttgg gcagtcattt
    21301 ttggaatcgc tatgagagaa gccagtaaaa atagtaaaga attgctaaaa actatcgctg
    21361 acgtgacttc taaaattgtc gaatggatca tcaatctgac tccatttgga atccttggtc
    21421 ttgtttttaa aaccatttct gacaagggag tcggaaggct tgccaactac ggtattttat
    21481 tggttctatt agtaacgact atgctttttg ttgcccctgt ggtcaaccct ttgattgcct
    21541 tcttctttat gagacgcaat ccttaccctc tagtttggaa ctgcctccgt gtcagcggtg
    21601 tgacagcctt tttcactcgt agttctgcgg ctaacattcc tgtcaatatg aaactctgcc
    21661 atgaccttgg actcaaccca gatacctatt ctgtttctat cccactcggt tctactatca
    21721 atatggctgg agtagcgatt accattaacc ttttgaccct tgttacagtt aacactcttg
    21781 gaattcctgt tgactttgcc acagcctttg tcctcagtgt ggtagcagct atctcagcct
    21841 gtggtgcttc aggtattgcc ggaggttccc tccttcttat cccagttgct tgtagccttt
    21901 tcggtatttc taacgatatt gccatacaaa ttgttggggt tggttttgtg attggtgtca
    21961 tccaagactc atgtgaaaca gcccttaact cttctacaga tgtcctcttt accgccgttg
    22021 ccgaatacgc agcaacccgt aaaaaataac tcatcaaggc aagcctgctc atgtcttgtc
    22081 ttttacgctt ttattctaac ttattaggaa attcttatgt ctattagcca acgtacgacc
    22141 aagctcatct tagctacctg tcttgcctgc ctgtttgctt attttctcaa tctttcgtca
    22201 gcagtttcgg ctggaattat cgctctcttg agcctatctg atacgcgtag aagtacttta
    22261 aaactggctc gcaatcgtct tttttctatg cttctagctc tggctatcgg tgttctagct
    22321 tttcacttga gcggatttca tatctggagt ctcggcctct atctggcctt ctacgttcct
    22381 ttagcctaca agatgggctg ggaaattggc atcacaccaa gcacggtttt ggttagccat
    22441 ctcttggttc aagagtcaac ctctccagac ctcctagtca acgaattcct tctctttgct
    22501 atcggtacag gatttgcctt gcttgttaat ctctatatgc cttcacgaga agaggaaatc
    22561 cagcactacc acacgctggt ggaagaaaag ttaaaagata tcctccagcg cttcaaatac
    22621 tatttatcca gaggagacgg acgcaaccga gcacagctgg tagcagaatt agacacgctt
    22681 ttgaaagaag ccctcagact ggtctatttg gatcactctg accacctctt tcaccagacc
    22741 gactaccata tccactactt tgagatgaga caacgacaaa gtcgtatcct gagaaacatg
    22801 gcccaacaga ttaacacttg tcaccttgcc gccagtgaaa gcctgatctt agcgcaactc
    22861 ttttcaaaaa ttgcaggtca actgagccag accaatcctg cttctgattt gctagatgaa
    22921 attgaacgtt atctggaagt cttccggaac cgcagtctgc ccaagacaag agaagaattt
    22981 gaaacccgcg ccacccttct tcaactccta cgtgaagcca aaaccttcat ccaagtaaaa
    23041 gttgattttt accaaaaata tagacagtaa tactcttcaa accacgtcag cgtcgccttg
    23101 ctgtatatat gttactgact tcgtcagttc tatccacaac ctcaaaacga tgttttgagc
    23161 tgacttcgtc agttctatcc acaacctcaa aacggtgttt tgagctgact tcgtcagttc
    23221 tatccacaac ctcaaaacgg tgttttgagc tgacttcgtc agttctatct acaacttcaa
    23281 aacggtgttt tgagctgact tcgtcagttc catccacaac cttaaaacag tgttttgagc
    23341 agcctgcggc tagcttccta gtttgctctt tgattttcat tgagtataaa aaagaaaact
    23401 tcagaccaat ccacaaaagg tgaatatctg aagttttctt ttatttataa gtaatcacca
    23461 taaaggttaa tagtagaaca aataaagcca aactcaccaa taaagtgagc accttgacca
    23521 aggtgttgct ctgccagtag cttggtttac caatattact agtggcatcc atggaaaata
    23581 gttgattttg acggggttgt atagttacca atacaatcaa agcaagagat aggataatag
    23641 ctaaaacaat tagcatttca atcattgatc tacctcaaaa ttcccaacaa agtaaagagc
    23701 aaaccaatca gaatcattaa gcccagtaaa agtgaaaaag ttttactaat cttctcccct
    23761 cgggtttctt tttccttctt gatgggtttt tgtttcaact cttccatgcg accttcaacg
    23821 tctttgtaaa ataaatcttc ctctgacatg ttagcctcct aaaacagttt gcattatttc
    23881 ttgatatcgc accaagtcaa cataatttgc atgttggcct tgtttgccaa gtgcctgacg
    23941 catttgatca acatctgaaa gggccaattt aatggtctca accaaggcag caacttcact
    24001 actttcaaat agatgttctg gagcgatata aagtctattg tgaaccgttt ggttaaatcc
    24061 aagaatcaag agattgtgct caaaggcctg acgcactgcc tgcaacaact cattgctgtg
    24121 attgatatcc aagtaaatat ccgacagttg atacagctcc tgaatcttct gtggactagc
    24181 attctggtaa aggaccacat taggatagcg aagcatgtct aagagcttag aagacatctc
    24241 tgtcactgct gcgatacgga aggtaacatc aggcaaggct tctacgattg cttctacttg
    24301 ctcaatctga tctgaattgg tcaagattaa ggcatctcgt cttaggaaat tatcacgttt
    24361 gaactggtaa tgataaccca agtgcacaaa ctgatcatgg tatttctcgt cagttaactc
    24421 taaagcgcgc tcataagtcg ccttatttgg aatgatgatc ttcttagtac gcacattatc
    24481 actttccaaa atcaactgca tattacctgg aatggcatca tagagaggtt cctgccatac
    24541 caagacatcc gagccagatt tatctggatg atggaaggaa accaagaaag gagtcgctag
    24601 agtattaaag ataagctgac tggtatctat ttccaaatct tgcaaaaaga aggtgataaa
    24661 ttcaacttta tttgcaaagt aacgcatgga ctgaccaggc aaagtcaata agatatcacc
    24721 cgtcacatgg ttttccagta aaacttgttg gccattgaca tcttggtaaa ctgtcataat
    24781 cggctcgcta tctgcgctat aagtggtttt agcaaagcaa gcaccaaagc gattgtagtg
    24841 gtcaacctga cgtactcgac cttctaggtc tttccagtct acctgtttaa ccaagcgagc
    24901 ctgcattcca tcaacataat gaatgacagc cctctcctgc gtcacatctt caatacaagc
    24961 agactgatta tctcctaaaa tttcccaaaa atctgaaacg ggaacttggt taaaatagag
    25021 aggttttcca tcctcgtaac ctagataata ggtaaaagga gaaagcagac catcaggcag
    25081 aaaaccatct gcatcgatga ccactccaag ttgagaaaga ccagtagcga ctagactttc
    25141 atgtaaatct ctactttctt gactgtaact atcataaagt tcaatcatgg agcacctcct
    25201 ctactgtttt cttccacttt tctaaaattt ctttggtcaa gaagccttct gcaatttgat
    25261 aagaataggc acgcatagct tccaaacgat tttcttgata caattgacaa atcttagcgg
    25321 cataagcttg cttgatttgg tcttctacat ggtcagatga acttggaatc aaataaccat
    25381 tttgcccatc ctctataaag gtctgattac cataaggcac atcaaaacca attagaggta
    25441 gacctgaacc aatagcttcc atcaaggtca gaccaaatcc ttcgctggta gaagccgtta
    25501 agtagacctc atactggcta taaatctgcg aaagttccgc atgccccttg agttggatat
    25561 agtcctctgc ctgatgattt gcaataattt ctctaagcag agaatcttct ccaccactac
    25621 catagatatc aaaggttagt tccggtaact ccttatgagc ttcaatcaca gctttcacaa
    25681 gccaatcaat gtgcttttct ttggcaagac gtgaagccgt aatcaatgaa aatggtttgc
    25741 gcccttgact tgaatctgtc aaggaatcaa tactgcctac aggaatggta acaatctttg
    25801 gctgatgctg agtatatttg gcaaattgct cttgtagaac ttcattttgt ctatcagtag
    25861 acacgataaa gaagtcaacc ttatctgcat tggtaaactg atagtcataa tagttattcc
    25921 aaaggatata gtcctcattt gtagcatttt cactataatg ctccgcatga acaactaccg
    25981 ctagatgtgc tgtctgtgct tcctcaaaca caacctgtcc aatacctgtc tccctatcca
    26041 gaataaccaa atcagacttg ttcaaattca aagatttcat aaaggcacgc acaaaagctt
    26101 gctttccata gaaaatctta tccttgaaat gataaacttc ttccttccct tgattcatca
    26161 aaatatcata gactggagtc ccgtcttcat tgtaaaaagt tcgttggtat aagactgcaa
    26221 cattgtcctt gggagcaaaa tactcgctac aataacgcgt ataagaaaag taatccttcc
    26281 gaatcaggtt tcccttaaaa acatactcgg catgttgaac caagtccttg ttctcatcaa
    26341 ccaaataaca ggttacaaac ttatcttggt caaaaaagaa tacacgtaaa accttgccat
    26401 ttttttctct gtgactttct tcaccaccaa agtaagccaa gacatcatcc actgtcacgc
    26461 tagtaggtgc aattttgata tctgtgaaat gattataaag ccagataacc tgattatcat
    26521 caaaaccaat attggctgtt aagtgctgaa tattatcggc taaaatcata tctgtaaaga
    26581 taaacttaga ggacagattt aatttccgaa aaacaccagc acgataggct tgagcgtatt
    26641 caacaccgct actagcccaa ccaattccta aatttatatt gtaaattgtc atattttctc
    26701 ctcttatgga aaatgagtca cgatttcacc ttttggagtg acctcaacca gccccatcag
    26761 gagattacgc accatatccg cacggatttg ttctttcata gcttcaaagc ccgcgtaggc
    26821 ttcttgatag tactctacga ttggattttt ctgactagca gattgaccac cgatagccat
    26881 ggatagctgt tgtagatagt ctacctgctc tacccagttg tcatcaatgg ctttaagcag
    26941 tgaaagtcgt aaaaactgtt catataagtc atgttgatta agtaattctt tcttttcaga
    27001 aagttcttta tcaatcacct gcttcataaa gctacgaact gcagttttgt cagttacatc
    27061 tatataatct ggaacctctt taacatgaaa actaatattg gtcacaataa agtgaaacaa
    27121 taattcacga ctagcatagt gatcagccgc tacctcttct gtatatctct caatgatatc
    27181 cacaacaaca tcctctaagt cacgagaacc atctattaga cgatttctct ctttatagac
    27241 tatatcccgt tgtatattca tactttcagc atactccaga gtctgacgac gtgctgaacg
    27301 tccagcacta tcactggcat gctgagcctt ttcgactagt ttccggtatt tacgaccttt
    27361 caatacttcc ggttgagtca tatcttgaac ctgatagtct ttgtactttt tatgcaccca
    27421 agatggacca aatttcttga taacatcatc ctctaaggat acaaaaaatt tactcatacc
    27481 aggatctccc tgacgaccag aacggccacg aatttgtagg tcgatccgct gactttccat
    27541 ccgctcagtc ccaataacaa tcaagccccc aagctctgcg actcctttac caagcttgat
    27601 atccgtacca cgtcctgcca tagaggtagc cactgtcaca gcccccatct gacctgactc
    27661 ggagataatc tgagcctcac gcgccgcatt attagcattt aggacattat gggcaatccc
    27721 ttcacgaaac aagagagacg aatagagttg agacatttca actgagccta caaaaacgag
    27781 taaaggattt cccttagcat ggtattgctt gatgtactcc aaggatgcat acactttttc
    27841 aggtaaagtg atatatagat tatctggata gtcaatccgt tgtctcggac gattggttgg
    27901 aatgcgtact acagacatat tgtaagtttc aataaactct ttttccgcga ccttacctgt
    27961 ccctgtcata ccagatatct tattaaacat cttaaaaaga ctctgatagg tgatcgaggc
    28021 catagcccgc gtctcaggag ataatttgac atgttccttg gcttcaatag cctgatggag
    28081 acctccttga agtttagtca tttccattag acgccctgtt cccttatcaa ccagtaccat
    28141 ctcatttcca cgaatgatat agtccttatc tttagtaaag agcttatgag ctcgaatcgc
    28201 ataaaccaaa tgacgagcaa aagacgcatg ctcttccttg tataaattat caatccctag
    28261 gaaattctca gcagacttgg cccccttagt agtgagccaa acctcctctt tctcctcttt
    28321 aaagatataa tcctctcctt cgaccaaggt tgttacaagt gtatcaatga tcgcatagta
    28381 attagactga acacgaggag aacccgcaat aatcagagga gtttgtgcac tatcaagcaa
    28441 gatatcatca atttcatcaa taataacata gttaaacggt cgtaaaaact taccttcttc
    28501 attcgaggct aggttatcat ttagataatc aaaacctaaa ctactattgg ttgtgtagat
    28561 gatatccgaa gcatagataa gcttcttttc ttcagctttc atttccttct ttggatcttc
    28621 cgtaaatggt acaccaatgg tcaatcctag aaaacgataa acttggccca tttcctcggc
    28681 atcacgcttt gataaatact cattaggagt cacaaccatc actccttctc ctgaaaaagc
    28741 gttcaaatag acaggcatgg tagctgtcaa ggtcttacct tcccccgtat tcatctcagc
    28801 aacatttcca tagtgcatga caatagctcc catgacttga acatcatagg ggaacatccc
    28861 taaaatccgc ttatctgctt cacgcaccac agcaaaagct tcaaccaaaa tatcgtctag
    28921 actttctccc tcggaaagac gctgacgaaa ctctactgtt ttagctacta attcttgatc
    28981 cgaaagagag gacatcttgc ctttcagggc attaatctgc tttaaaatct ttttcacttt
    29041 cctaagctgg aaatcttgac ctaaacgtct aaacacttct gatctccttg atagaaaaat
    29101 gataaaaagt taaggactca aatccagcac ttaaaagaga aacttgataa gtataactat
    29161 cttctggata agtaaatatg aaatctttcg ctttttctac ctttttttct aaaatatcac
    29221 catagcggtc aaaaaaagtt atcttggtat aaactccatt ttcaggctga caatcaaaaa
    29281 ccagtgatag ttgatactcc tgctttcttt ttaataaggg aagctgaggt tgggttcgtg
    29341 cagcctggta attgacacta gaaaaccaag tctttagaat ctcaccagat ggcaatagag
    29401 gattatacag acgaacactt ttgtcaaggt aataagatac agttgttcca tacatataag
    29461 tcccaccaac ttctccccaa taaatagact gtctctgtgt aataatcatc ttttctccct
    29521 tccaaaacca gtctctaaga ccattctata aaagtgcaaa aaccaagaaa tattggtatc
    29581 tgtatcatca ttgtgtcgtc cagcagttcc tttagataaa atcttcgcac ctgtattaca
    29641 cagataagac actaattgtt cataggcttg tggatccatt tcttcatctt tcatatagga
    29701 taaaccaaag gttgtctttg aaaaatttgc ttgtttaaaa attttccaaa aacgctgatc
    29761 caactccgtc atatcttgag aacttgtccc acctgtatga tgaattaaac aatcaaaagc
    29821 taagttagag acacccggtg cgtccaaacg tccacgacta gctatagttc ctaaattagc
    29881 caagggctta ccaactatga tggcatgggg ttcaaaagaa gcaccataat agagagccgg
    29941 aaacgttccc atagaaagac ctgataaaat caaatcctta tgatcaaagc ctaaataatc
    30001 aagatagtga gtgatcgtat cctttacttt tccctctagc tcatccgttc cgagataaaa
    30061 agctcccccc tctaaacgtg gatcagaaaa taaaatgaag ggacatccaa gagttttcat
    30121 cataaagtaa ccctcgaatc cttctgcagg tcgataacct gcaaaataga cagtcaaagg
    30181 cggtttaaaa tcacctggat ggaagaaata gtttatttca tcacgcttgg aatcatgtag
    30241 gatatttcca ccaagtacaa acttaccaaa ttgttttcga ctccatcgtt ggtgaagatt
    30301 acctagtttg atagttccac gacctcttgc ttcaacagat atcgagagaa agtagtctcc
    30361 gtctcgacta tccataaaaa gtgcttgctc caagtctttt tcagatacta ttacttcttc
    30421 aaagaaatca tcaacagacc cactccacat tttacggatt actaaacgaa agtcacaatt
    30481 gccttccttc tcatattcaa gccacaactc aatagggagt gttttttgca ccataatatt
    30541 ataagcccaa taggcaagct gggcaaaatc ttgcccaaac tcaccttcca aactgacata
    30601 atccaatcct tgataagaaa tagctcctgt aaaatttgga ttgacttgta tcgtcggagg
    30661 aaagagttta tcaccatacc caccgccaaa aagagattta cttaaatcat tgattagttg
    30721 ttggggactt aaaaaatcaa ttgcttgtgc acatcgtttt tttagaaaat ccacaacctc
    30781 tctatcattt atttgtagat tctggttata gaacaaagta taaggttcaa aatattttac
    30841 ataggaaaat aagtctctgg aatactgacc atcttctatt aaaactgcat gaaaacggtt
    30901 aatatcctct ttttcgatta tttcacgaag ggtttttgat gagtttgggt aaaaataata
    30961 ccaactcata ttttcaggta tgtcatagtg attttcccaa ttggcaagtc ctatctgtaa
    31021 aatattaagt tcctttgaca tttttaacct cctctatcca tttctctaat tttccaagaa
    31081 attgttgtcc tgtgtgctcc ttaatcttat caattgaata tatcaaggac tcattccact
    31141 ccttcaacct atctgtgtaa taatgtgcag ccttagaaaa ttctgtcaca tctgtcagca
    31201 aataaccatt ttttaaatgt tccacataga cggtttcaac taggttgatt tgaggaattc
    31261 ctgcactaat cccagcaatc tgtgtgtaga gatgaggatg tctatttaaa tccacaatca
    31321 aacggacaaa ttctagtgtt tttatcaaat ctaactcatc attcaagtta acaaactgta
    31381 agcgtaagtc ctggtgttga ttttcttcca ggggattttc tgcatcacca taatcaatcg
    31441 cctttcccag attttcggat tgaatgtttt cttggatgaa agactcaaca atcccttcaa
    31501 cctcattcat ttgctcctga ctagcagcaa aggctccaaa aatcacctca gtatccttat
    31561 tttcagcgac aaaggacaag acttgaagca gagcttgatt atcaatcccc tgctcaaaat
    31621 ccagttgaaa ataaatgatg gattctttct tagtttggct tcgtcccaat cgtaatcggg
    31681 tgtcaaaaga tgataaatga taacattgat gcattcgttc aggatacaac tcctgcaaca
    31741 atcgtaaact atcctctcta tccaccaaaa tcaaatccga tttttcaaaa gttacatcta
    31801 aatccctaaa ggtatcttga ggattacgtc caatgaacag actcaacagt ttaggattag
    31861 tactaggtaa acgatctagt accaactggt catgatgaga atgagaagga agcataaaaa
    31921 tatcctgatc cttcacatac gtttgcagat aattctcaaa aaattctgcc accagatctc
    31981 ccatattttg ataggtaagc attttaaagc gataacccaa aattggattg acttctacct
    32041 gtcctccttc ttttaaacgc tctctaaatt gccaaactcc cttaggattc aaatattctt
    32101 gataggctgc ttgcccatct tcaaaaaaaa taatactcga tataaaccct cgatcatcca
    32161 tgatatggtg catatgtatt tgaccatttg gttcaaaata ctgtatatca ctgatgaagc
    32221 cttcaactcc atgttcaacc ttagcaaatt tcttcccatt tttttgaacg ataatcgtaa
    32281 agggactata aataaattca cagtcatcat cccactcaat atctctaatg cttaaaactt
    32341 gggtatggag attatgaaaa tcttgcataa catcaaaaac ggaataagta tccgtttcta
    32401 acacaccatg tctatataaa aaataacgta gatgaggctg gtaagctaat actaatagac
    32461 gagaatctat atcttgctct tgaaagagcc ggatctggtg aaaggtatca tcaaactcta
    32521 gacgaaaatg agaaaaatac catggagtga tatctgcatg ccatgttctt tctgacccat
    32581 accaagctgg aataaaataa tacataaaag tctcctaaat caaaggttta taggtctcat
    32641 ttagccttaa agccttgacc tcgtctctaa tcgtaaaaat catgcctcca aacatcataa
    32701 acaaacctgg aatcattgcc aatcgtaata acttttcatc aaacaaaaca aaaagcatgg
    32761 gaccacctgc cataaccaca ttaaagagac cacctatgac tgagaaacga aggaccaatc
    32821 gattaataaa tcgactagta tccgcacctg gataaatacc ataaatgtat tctccagatt
    32881 ttttcatacg gtctgcaatc tcttctccat tcatcgtaac aaaagcaaaa atgatactaa
    32941 ataaaaataa gaccgaaata taaacataga cccacaaagg ctttccaatc ataaattcct
    33001 ttgataaagc cgctaaccct gaatgattag ggaaaataaa tcccaacaag atgaacaaat
    33061 aagctggtac actaagaaaa ctcatcacat acatataagg catcccacct gcaggattca
    33121 acatgatttc gagataaaaa tagcgtttaa atcgattgtg taagccaatt ttattaacag
    33181 gaaccaaata gcgagctcga tacataaggg caagtaaata agaaaagaca agggttaata
    33241 aagcaagtaa cacaataatc cctgttggaa tgtgtactgt ctgaaatgtt tccaaaacat
    33301 cctgaggaat atttaaaacc atactggata ggagaatgac tatagaacct ccaatcccca
    33361 tactcgcatt taaatctgac aaccaaacaa gaaaaaatgt tcctgctatc agcaatattg
    33421 tattcattag aacaaccaat attgcagaat aggaggattg tactggcagt ctcaagctaa
    33481 ctgccaatga ttgaatgaca gctatcatca aggtcaggta cattttacgg cgatcttgta
    33541 tttctataga cgtagatgtt aaacccaacc gtttagaaaa agaaaacatc tgccataaaa
    33601 tcatagctga catccaaggg gacaatccaa cagaaaaaat tgacaaactt cttagatttc
    33661 cacctgttag ggcggctgag aaggctagat aggctgttga acctcctaaa aaatctttag
    33721 tatttaggtc aacaaaaggg agagtaatac gacttcccaa tacatagata aacagtagaa
    33781 ataaggtaaa tagtcctttt tttactgcta ttgacgaata aatcttagtc ataaaacact
    33841 cccctcacct tcattgtttg tgatatggta aataacaatt cttttatttc aacttttacc
    33901 atttctttgt tctgcatcaa aaaacaactt taatctgaaa caaatatctt tatattcctc
    33961 agtatctgtt aattgatggt attctaaagt ttgcttataa tcttttaaaa gattgacaaa
    34021 tcgaatacgc agaacggaga catccaaacc agccaagaca caatccgata ttttcttaga
    34081 aaacacttca acaatatctc ttgcccagga aagatcaaat tccgttctca tgatgcttcc
    34141 tgaacgtctt ctatacagat agagattatc gtttataaag acgattttag aggctaaaag
    34201 ataaaagcga tgcatagttg cttcatcatc aaagcggcga ccatttgaaa agtgaacttc
    34261 attgaataat tcttttttaa tcaacttaaa tgtcggcaat ataaaggccg agctattgaa
    34321 tttccaatct cctgcttgac ggttcataat ttcttgtata gctaattctt cgacgcaaaa
    34381 atcttgccct gttacataaa aataaaaatt cccgtcactt tcgtcataat tatagtaatt
    34441 ccctataaca acatctgcat ccttttcttg gacttgctga taaagagttt caatcatatt
    34501 ttcttttacg atatcatctg aatcaacaat cgtgatgtac tctcccttag ctacactaat
    34561 ccccatattt ttagcttgtg ctgccccccc ttattttctt gatgcaatac tcgcacacga
    34621 ttatcttgca tcataaaagc atcacaaatt tccccagaat tatccgtaga accgtcatca
    34681 actaaaataa tttctatatt ttgataggtt tgcttcagaa tatgctcgac acactccact
    34741 aaatattttc ccgtattgta tatcggtacc acaacactaa ttaattcact cattactcta
    34801 tctctatatt cttcattcta tccactaaat catctggtct ctccacagaa aaaataccgt
    34861 catagagtcc atcatccata cttttacgtg tgatatcaaa agcgaagatt ttcttgccac
    34921 tttcttgtgc ccttgtaact acattaaaaa cctctccacc tgtattaata tctaaataaa
    34981 ctatagaatc gtccaatagc caatcaattc tactatgtaa tacattttga tatactgtta
    35041 cattcgtata ctgtgataga gaggtcagct cctcagaaca atcacacggt gcagccaaat
    35101 gaaaatgcca atcaggtaac cgttgtacta aatactctaa atgttttata tctgcactcc
    35161 atgtcacaag catcacttgt tttttagact gattgcttct ttcaaaataa tttaaatcgg
    35221 aacgttgaaa agcaatctct gaccaatcca aatctctata aacccaccat aattcacgta
    35281 gtctagatat actatatgta ttccaaggtt tatcatgact agcatagtga acaattgtag
    35341 gtggattgtc atctagacgt tcacattctt gagcaaggtg ataaatatca acacccacca
    35401 tataattata tgttttatct aaggctagcc aattatcctc aaaataaata tttaaaatac
    35461 tctgatcccc aagatgaaca acttgatttt gctcggccgc taattccaat aaactattga
    35521 caatagagtg ttctttccat tttgcaacat ccattagtaa cataccagca ttaaatccag
    35581 attttcgtcc ttcataggca tagacatcat caacagcacc aattgaatat cctttgagat
    35641 ctatctcaaa caaagtagct agttccccag ttacaatgat atcggaatcc agatacaata
    35701 ccctatcaga ttcaaccact tctgtcgcaa aaaatctaaa gtaagaagca taatttatat
    35761 gaggtcctgt tttatagctt tcaaaaagtt ctttatcaat gtgtacactg cgaattgtag
    35821 aattcacaac ttccattttt ctccccaata atttaaacca ttcaggagct atatcactgt
    35881 tgagaatata aaaatcaaca tctctattgt gatacaatac agactttata gtcgtctcta
    35941 aaggaataag ataggcatta tctgccgcta atactattga ttttctcata ctgttctcta
    36001 cctcatgtaa gatctgattg ctgcaaccat ttttttcgga atggagcttg gatagatacc
    36061 ttcatatgaa atctcagaaa gattttcaga gcaagtattg tcgaaagcta tcattggttt
    36121 tttgtactta agcacaaact catatgcatc ttctaatttt cgatcatgat tcaaatccaa
    36181 atacaaatct gaagctatta ctatttgttc caataacatt ggtaaggaat ttggatatac
    36241 ggtaacatta ggaaaacgcg ttaaagctag tagttcattt gccatatttg tataagcaac
    36301 aatatgaaaa tgaacttctg gcaattgctc cgccaaataa tcgattttct cgacacacca
    36361 agaattcgtt aaattaacac attgtaactt aaatatttgt gatttactag gatacttcac
    36421 actctttgaa aaccattcat ttaaaataac agaccaatcc atcaaagagt attcccacca
    36481 aacttctctt agacgtccaa cagaaaattg attccaaggc ttatcctgag aaatatagtg
    36541 taaaattagt ggcagtggtt cgagcggaat atcaaaaatg aattgatgtt taaaggctgc
    36601 cgccccataa tcatatccta tttgaaaatt atattgatct tcaagggaac tatattgatc
    36661 tttaaacaac atattcaaaa ttgactggtc tccttcttcc acattctcat gttctttttc
    36721 tgttaagtca atcaattttt gtcgaatagt ttcagatccc cattttttgt tgttaatcaa
    36781 gagaacacca gcattgaagc cgactcctgc tccaaagcaa gaacgagctg ctgccaaata
    36841 attttcacct aagtctaatt caaacaaatc ggtcaaatca ccagtcacaa tcaaatcact
    36901 atctagatag agaactttat cttctgttac aaaatctgga ataaaatagc gtgcaaatgt
    36961 catatgattg atatgaggta atttattaga ccaattcatt tgaaactgtg agccaattaa
    37021 cttgcagtca atcaagtcgc cccccatctc ttgtaaatat attcttattt gactaaacca
    37081 ttcctgagga atgtcctgat ttagcagata aattttcaaa tgactattgt gtctacagag
    37141 tgacttcatc gccgtttcga tttgtcgaat ataagcgtaa tcacctgcaa atgctacagc
    37201 gcgtttggta tttctcattt taaatcctta tcatttattt taaatagtct agtttaatat
    37261 tcgtgcaaca atctgactgt tataggtttc atcatcaata aattcaatat cttgatcaaa
    37321 attatactct gcagtatgtt tatgagaaaa tttaacctta gttttagctc ccattttcat
    37381 ccattcatac tctgagtcaa tatggcctac atccaaaact tgatagccca tctggcatag
    37441 attataactc agaacttttg ctgtaggacc cagcatacat aaaatcaagc gaccaccagc
    37501 atacttttca atttcttgtt caatttcatg aactctagaa aaggcactat gagaaggaca
    37561 gataattcgc ttaatagaat ttgcctcatc gaataaatca tttccgacac ctgaacgaga
    37621 agtcgcacct tcgactatca gtaagtcacg gttttcccaa atgcttttca atttttcaaa
    37681 ttgagcttta gcttgactct tgtcttcaaa atcgatataa gggcgagata caaaggttga
    37741 gccataccat gaatcactgc ataactctct gtaaaaatcc atataatgat ccatgtgatc
    37801 tttccaaaat ggaatcgccc acgatgtaaa cctaaaacga tctgtaaaag catcaggaag
    37861 gcacactact aaatcttctc gactttcttg gccgataatg tccctcatga ttgaaaccaa
    37921 ctcttcatca taatcctggt agggaattga atgccctgca agcatattga tttccccatc
    37981 tccaaaacga actaaagaag agttgtgttc aataatataa tccaaggttt catctatccc
    38041 tttcacctgg attatatcaa gcggtttttc tagcatatcc ttagttatca atttttgcaa
    38101 atcagccaac attcgttcag gatgttcact tgaatacaac ctttggccat tattcccatt
    38161 ttgagattta taaaaggcta gtataggttt agatagatga gccatttctg caacgatatc
    38221 ggatgttgaa gtcagtaggt tgatatctaa ataagcatcc atcttctcct tcaactcgtc
    38281 tagcttatct ctagaaattg ccggatagag ctgaatatta ggataacgat tagacaaatc
    38341 atataatttt ggccccatag ctgtccaagc agcaacttga aaaacaacat ttggcaactg
    38401 tccagccaag taatccaatt gttcgatatc ctgagaagcc gtaaacgtta aacaagttaa
    38461 acttggaagt tgtcgaaaac aggtaagatg tccgtttttc ttaaaatctt taatcgtatc
    38521 aatcataaag gaaactttcc cattttcgaa aacgatttgt cctaactctc cgtgctgagt
    38581 cgattgaaaa gctagtagcg ttttttcttg ttcttgcaaa gattttaaaa agttctcatc
    38641 tgcactacca tgattgatat ccaaatatag atttgttgac tttttcagct tatctaatac
    38701 aggaggaaca atttgtggat gcaatctcac attatcatac acagctaatt ttatcagctt
    38761 atcacccata tccgtccaag cagcaatatg aaataccaca tctggtaaag ctgtgactaa
    38821 ctcttctatt ccttctaaat cttgggaatt tgtcaaagtt aaacaagaaa attccttatc
    38881 taaagacgat gtcagttcaa actcccctat atgatgttgt aaaattttag tccattccaa
    38941 atcatgaaat tcccaccata aatcacgata acgattggct atcaaggtgg tccagggttt
    39001 tctgtaagac acaaaatgaa taatactagg aggtactaac tcattaaaat aattttccca
    39061 tttattataa aaagcagtta catcatgacc cacttgaagg ttaaattctt tatccagctc
    39121 taaccaatca tcttgtaaga cctgattaaa aatcgtttga tcaccattaa aatgctcgaa
    39181 acggccttct tcaacttcct tcattgtaac aatgctctgt tcaattagtc gttcttttaa
    39241 tttctcttga cgccattttt tattgttgat taataaaaca cctgcattaa atgtaattcc
    39301 atctgtatct ttaactgctg cgagtgattt ttcttctaaa caaatactaa ataatttctc
    39361 taaagaagta tttacaatca aatcactgtc taaatataaa accttatctt cttggatata
    39421 atctgcaata aaatatctag tataggtaat gctactaatg tgatcttgct tttcccaatc
    39481 ttgaaacaca gtttgttcag gtagcttcac atcgataatc tcactaccta acatgcgagc
    39541 tatttttcgt ggtttgcgaa accaatctgg cataatatct tgatttaaaa tataaatctt
    39601 aacatctcga ttgtggtata aaatagattt tatggttgtt tctaactgcc tgatgtaatt
    39661 acgatcacca gctaatacaa ttgttttaat catcttgttc tcttattcaa ctcccaaatg
    39721 gtaaattgca tctaccaata attttttagt aaaataacct tcttttagca aataactaaa
    39781 ggtttttatc cgattcgtca tttcttgata ttcttgtaga ttcattttat caactatcgc
    39841 atgaacttct tctagactat tcgccacaaa gcctaagcct tgatctacta taaatttagc
    39901 agttgacaag ctacttggta caatgactgg gatgcccgct gtcagatagg tactcacctt
    39961 atgagatata tttaaggtat aatattggtt gctttctcca tcgttttgat aagttcccca
    40021 gacaaggcca aatccaccct ttgataattc tagcaacaat tcctcatctt ttttccatcc
    40081 ttcgatgctg agatttctag cactagaact agcttcccct ttatttgaaa atactctcaa
    40141 aggcgtatct tgagaccaat tttgtaagtc tggaaaacgc tctaaacttc cagcaaaaaa
    40201 aagttctttt ttaaaagcag gggtgtataa ggataaatca tgaggatgat cccacatccc
    40261 ttgaacaaga atcttcttag tcgtcaatcc ttcttccatc aggcgtgttt tcattctctc
    40321 tgacggcact atcaaaacat ctgatagatt atacatgtac atatagtctt tcatgagata
    40381 atagttacta tcaaacatga ggggaacaac atcatggata aagcaaataa ttttcacctg
    40441 catatccttc aacttatcaa acaagagacg atcaaattca aagccattcc aggttggaga
    40501 ctgaaagact aaaatatccc caatagaaat actggccata ataccatcca gacgcttatt
    40561 catttcagaa ggactatctg aagcaatgtt gtaaaaataa ataccaacct ctctaaatcc
    40621 cagttgacta gctatctttt gaacagcatt ttgagctaag ataaccgtac tatcaccagc
    40681 catgccgtat aaatttgtta aatgtagttt catattacgc tatctcattt tttattacta
    40741 tctacggaag taaagacaat ttttccatca ttcttctata aatctctgtg aactgcatat
    40801 tttgttcttc taattttgct atcactcttt gtaatctatt tttataaatc aaaatatgat
    40861 tggtcaagtc atagtctgaa cttgctaaaa tagctatctt ttcttcccta gccccgattt
    40921 catcatacat acgcttttca ctccatgtat tcgataaagt atcagataaa ccaacacggt
    40981 accagtaaac acaacgattc aaatagacta tcctcgaagc tcttagaagt accttccatg
    41041 tccagtaagt atcctctgca atttttccta taggaaatgg taaatcttgt agtaactctc
    41101 tcttgaataa cttcaagaca gctacagtcc agttcccatt tctgacttct tcgacacctt
    41161 ccctatccat gattgcttta ccttctatca cttccagaga atcatctgga tccgtaacat
    41221 aagtcatata cacatagcgt gtttcatcat aagaattata acgcccgata ctaatatctg
    41281 cgttttcctt tttcaaagca ccatataatc ggtctaaagc atcatgttcc aaccaatcat
    41341 cagagtctac aaaagtaatg tacgcccccc ccgaacattc aatacctagg ttacgagctg
    41401 atgaaagacc gccgtttgct ttctcaaaat atttgaaacg agaatctttc tctacaaatt
    41461 cttcacatat tttggatgaa tgatctggag agccatcatt aaccatgata cattcaaaat
    41521 tcggataagt ttgtttttga atactatcca aacactgtcg caaataattc tcaacgttgt
    41581 agattgggac tacaatacta attagttcat tttccatata ctaactttcc tagacttgat
    41641 ttattctatt tccctcttaa tctcttctct ttacaacaag atttccatta ttataaacta
    41701 cactgtttga tggaatatca ttgcgtatga gacaacctgc tccaataatg gtattatccc
    41761 caatcgtcac tccttttaaa atcgtgacat tacttcctat ccagcagtct ctgccaactc
    41821 taatcggcgc tgtagtccac tgccactttt caatcttttc agcagtataa atatggtcgt
    41881 gatcataaaa acgaacaccc tctcccatca tggtaccagc tccgatttca attctttcca
    41941 tacagttaaa actacaagag ttgttgataa aaacaccatc atgcagtatt aacttaccag
    42001 aagagacatg aaaattttca aaatttctgc agatgacatt tgctcctaca atgaagtgag
    42061 ccttatcatc gattttaaag acattccaag tcccatcttg gatgattttt tcttgatgat
    42121 tggtgcctac tctgacttca ttcagatagt ctctcactct agaaaccaat ttgtctggtg
    42181 tacttgatag aaaaacttcc tgcccctgat ttccatggac tgtattgtca aaagcaaaga
    42241 cagattttcc agcctgtaca aacttggaga caatagcatc tacttcttga aagtgattga
    42301 tatctagtaa aaagtcacag gtatcgacta gaaagtttag ctgttcttca tttgtaatcg
    42361 ttcggagacg gacattatag ttcgtttcta agctacggat tttctcggaa aattgaacag
    42421 gtgctgcaat ataaaaacag atatttggca aggattcaag gagataatcc aactcttcaa
    42481 tctgatcact aacagtcaaa atcagagcat ctcctactaa atgatttttc ttcatttgct
    42541 tatttctctc aatttctcaa tcattgcttg aacttggtca acagcatata cctcctgacc
    42601 tgcttcatag gttttggtat tttcaaagga caaaatagtt tttccaagtc ttgcaaattg
    42661 attgataatt tcctctgttt tttcaccatg attaatatct aaaagtactt gactggtttc
    42721 taccaattca ttatcgacat ctaccaaata gtgaattccg ttaaatatag tcacgtttgg
    42781 ataaattgtc atctgagcca atcgatcact aactattact ctagctgcta tcttaaactg
    42841 aatatcaggc aaggattgaa ccaatgtctc aatttgttca atatggtctg aggcagtata
    42901 gattagacaa gtgaaaggtt cctttattgg atagatgtga gatctttgta atggatgtaa
    42961 atgatggttt tgtcccaatt ctgtccattc aagcccatga tagtaccacc aaacttcacg
    43021 ataggtttgg gccgccaaat ctttccacgg tttccgatga gaaagatagt gaataatagc
    43081 aggataatcc tgaccctcag gcaattgata atcagcaaac tgtttatgaa tgacaatatg
    43141 attataatca aagtccaatt ccaaccattt atgttcaaaa agcatattca agatgctctg
    43201 atctgcctga tccaccttat catgccattc attggttaca tcaattaatt tttgggtcat
    43261 attctctttt ttccaaaaag cattgtttac caagagaaca ccggcattaa agatttcttg
    43321 accaaaataa gctctgcccc caaaatctct aacagcagcc aaaggataat cttgtaagtc
    43381 tgtagcaaac aaatcatcaa gatttttcgt tacaagtaaa tcacagtcca agtagagggc
    43441 cttatcttct tgcacgaaat cagctatgaa atagcgtaaa aaaactgtgt aactaatatc
    43501 cgttttataa catgaaattt gctcagaagt tacccgacaa ttaataattt ctgagtcaaa
    43561 cttctctaag cgcttattta attgcttaat ccattcattt ggaaaatcgc tatgaatcag
    43621 ataaaaacga atcgaacgat tatgataaca aatagacttg attgtcgtta aaacttggtc
    43681 tacatagcca tagtttgctg ctaggacaat ggctttcttt tcacttgatt cttgtaccgt
    43741 taactgattt aaaagtcttt ttttcatttc aaactcttta tatattgctg tgtcagataa
    43801 accactagct tgaccgttgg cgagactgac ttccaacatc tgacgataaa ctgccaagtg
    43861 tttctctaga ggatatccca tattagctag tagcgtaata cgttcagaca tagcatcaac
    43921 taaggcgtgc atccactttt ctgtccaaac tcttgataga ctaccttttc taatccgata
    43981 agcataaaga cctttattta aataaattac cttttccgat aataaatata ccttttgatt
    44041 gaggtaacca tcttctccta atttacccat gtcaaagcgc aactgctcaa acaatcttgc
    44101 cttatagagt ttaccacaag cagatatcaa agcaaaactc ttcatttctt gagtttcata
    44161 acaagttctc aaagatggaa acattgtcat ataccttatc ataataggag tctcctgata
    44221 tatgaaagta gaacattcct tcactttcgt tgaaagaata gtaattccca actgcaatat
    44281 cagcttgata ttctgttatt tttttatata gggtttctac ataatctaac tcaatccaat
    44341 catctgaatc cacaaaggtc acataatttc cggacatatt attcagaccg gtgtttcgtg
    44401 cggcagaaat accagcattt tcttgttcta tatagagaat tcggtgatcc atttctgaaa
    44461 attctttaca aatttcacct gaagcatccg tagaaccatc attaacgaca acaatctcaa
    44521 tatttttata tgtttgagaa ataatactat ctagacattt cctcagatag ttttctacat
    44581 tgtatactgg tacaatgacc gtaattttat catccactag caattttctc cttgatttat
    44641 gtgcgcgagt tagtttagcc taactttaca ggttgtctta ctcttcttca tcacgtttac
    44701 ggcgtttcgc aaccaatcca atacctgtaa cagctgctag aactccaagt aacacagatc
    44761 caattgacga ctcagtacct gtattaggca attctttttg ggatttacct gtcgatccag
    44821 aagcatttcc aacttgtgag ttcgaatggt ttgctgaatt tgaaactgat gtacttgctg
    44881 aggctgacgc actcgttgat gctgactcag acgcactggt tgatgccgat tcagacgctg
    44941 aggtgcttgc tgatgctgag gcactggttg acgctgaagc tgaggcgcta gtacttgctg
    45001 aagccgaggc actggttgat gctgaggctg aggcgctagt acttgctgaa gctgaggcac
    45061 ttgtcgatgc tgaggccgaa gcactggtac ttgctgaagc cgaagcactc gttgatgctg
    45121 aggctgaagc actggttgac gctgaagctg aggcactcgt tgaggctgaa gccgaagcac
    45181 tcgttgatgc ggaagctgac gcactggtac ttgctgaagc tgaggcgctt gtgcttgctg
    45241 aggccgaggc acttgttgag gccgattcag aagctgaggt actcgttgat gcggattcag
    45301 atgctgaggt gcttgctgag gccgaggcgc tggttgatgc agaagctgag gcactggttg
    45361 acgctgaagc tgaggcactg gttgaggccg attcagaagc tgaggtactg gtgcttgctg
    45421 aagctgaggc actcgttgat gccgattcag acgctgaggt gcttgctgaa gctgatgcac
    45481 ttgttgatgc tgaggctgag gcgctggttg atgccgattc agacgctgag atacttgctg
    45541 aggctgaggc gcttgtactt gctgaagtcg acgcactggt tgaggccgat tcagatgctg
    45601 acgtacttgc acttgttgac gccgatgtgc ttgcacttgt cgatgctgac gtgcttgccg
    45661 atgtacttgt gcttgttgat gctgacgtgc ttgctgaagc cgaagcactg gtgcttgctg
    45721 aagccgatgc acttgtactt gctgaggttg atgccgattc agacgcactc gttgatgcgg
    45781 aagctgacgc actggttga
//
LOCUS       DAVBEM010000010        45159 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVBEM010000010 DAVBEM010000000
VERSION     DAVBEM010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45159
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.010"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(56..1066)
                     /locus_tag="VQ548_000588"
     CDS             complement(56..1066)
                     /locus_tag="VQ548_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HET2653492.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            1215..2384
                     /locus_tag="VQ548_000589"
     CDS             1215..2384
                     /locus_tag="VQ548_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2653493.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            2381..3151
                     /gene="recO"
                     /locus_tag="VQ548_000590"
     CDS             2381..3151
                     /gene="recO"
                     /locus_tag="VQ548_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HET2653494.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            3148..4140
                     /gene="plsX"
                     /locus_tag="VQ548_000591"
     CDS             3148..4140
                     /gene="plsX"
                     /locus_tag="VQ548_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HET2653495.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            4146..4379
                     /locus_tag="VQ548_000592"
     CDS             4146..4379
                     /locus_tag="VQ548_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET2653496.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            4425..4716
                     /locus_tag="VQ548_000593"
                     /pseudo
     CDS             4425..4716
                     /locus_tag="VQ548_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            4919..5149
                     /gene="blpU"
                     /locus_tag="VQ548_000594"
     CDS             4919..5149
                     /gene="blpU"
                     /locus_tag="VQ548_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET2653497.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            5864..8017
                     /locus_tag="VQ548_000595"
     CDS             5864..8017
                     /locus_tag="VQ548_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HET2653498.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            8030..9379
                     /locus_tag="VQ548_000596"
     CDS             8030..9379
                     /locus_tag="VQ548_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HET2653499.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            9550..10257
                     /locus_tag="VQ548_000597"
     CDS             9550..10257
                     /locus_tag="VQ548_000597"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HET2653500.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            10459..14184
                     /locus_tag="VQ548_000598"
     CDS             10459..14184
                     /locus_tag="VQ548_000598"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HET2653501.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVTKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            14277..15719
                     /locus_tag="VQ548_000599"
     CDS             14277..15719
                     /locus_tag="VQ548_000599"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HET2653502.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            15756..16778
                     /locus_tag="VQ548_000600"
     CDS             15756..16778
                     /locus_tag="VQ548_000600"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HET2653503.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            16775..17320
                     /gene="purN"
                     /locus_tag="VQ548_000601"
     CDS             16775..17320
                     /gene="purN"
                     /locus_tag="VQ548_000601"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HET2653504.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIALVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            17404..17913
                     /locus_tag="VQ548_000602"
     CDS             17404..17913
                     /locus_tag="VQ548_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET2653505.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLIFFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            17938..19485
                     /gene="purH"
                     /locus_tag="VQ548_000603"
     CDS             17938..19485
                     /gene="purH"
                     /locus_tag="VQ548_000603"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HET2653506.1"
                     /translation="MTKRVLISVSDKADIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYDDAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGENKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            19607..20869
                     /gene="purD"
                     /locus_tag="VQ548_000604"
     CDS             19607..20869
                     /gene="purD"
                     /locus_tag="VQ548_000604"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HET2653507.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVSETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFFEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNITWTDKGVTLGVVVA
                     SKGYPLNYSKGVELPVKTDGDIITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            21272..21760
                     /gene="purE"
                     /locus_tag="VQ548_000605"
     CDS             21272..21760
                     /gene="purE"
                     /locus_tag="VQ548_000605"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HET2653508.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            21747..22838
                     /gene="purK"
                     /locus_tag="VQ548_000606"
     CDS             21747..22838
                     /gene="purK"
                     /locus_tag="VQ548_000606"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HET2653509.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            22848..23075
                     /locus_tag="VQ548_000607"
     CDS             22848..23075
                     /locus_tag="VQ548_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HET2653510.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            23138..24436
                     /gene="purB"
                     /locus_tag="VQ548_000608"
     CDS             23138..24436
                     /gene="purB"
                     /locus_tag="VQ548_000608"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HET2653511.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(24491..28429)
                     /gene="strH"
                     /locus_tag="VQ548_000609"
     CDS             complement(24491..28429)
                     /gene="strH"
                     /locus_tag="VQ548_000609"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET2653512.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEDDKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVNLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGSMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQTLNEVPKDLNRY
                     TAESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVIEKKLPETGTHDSAGLVVAGLMATLAAYGLTKRKED"
     gene            complement(28744..29460)
                     /locus_tag="VQ548_000610"
     CDS             complement(28744..29460)
                     /locus_tag="VQ548_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2653513.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            29808..31595
                     /locus_tag="VQ548_000611"
     CDS             29808..31595
                     /locus_tag="VQ548_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HET2653514.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPVYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            31592..32068
                     /locus_tag="VQ548_000612"
     CDS             31592..32068
                     /locus_tag="VQ548_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET2653515.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            32096..33001
                     /locus_tag="VQ548_000613"
     CDS             32096..33001
                     /locus_tag="VQ548_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2653516.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            32988..33803
                     /locus_tag="VQ548_000614"
     CDS             32988..33803
                     /locus_tag="VQ548_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2653517.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            33810..34214
                     /locus_tag="VQ548_000615"
     CDS             33810..34214
                     /locus_tag="VQ548_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2653518.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            34513..35679
                     /locus_tag="VQ548_000616"
     CDS             34513..35679
                     /locus_tag="VQ548_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HET2653519.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVAKPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTTLLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVVLGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            35795..36832
                     /locus_tag="VQ548_000617"
     CDS             35795..36832
                     /locus_tag="VQ548_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HET2653520.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGALLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            37040..37894
                     /locus_tag="VQ548_000618"
     CDS             37040..37894
                     /locus_tag="VQ548_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2653521.1"
                     /translation="MTYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREYYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            38044..38301
                     /locus_tag="VQ548_000619"
     CDS             38044..38301
                     /locus_tag="VQ548_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HET2653522.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(38677..38769)
                     /locus_tag="VQ548_000620"
                     /pseudo
     CDS             complement(38677..38769)
                     /locus_tag="VQ548_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(38805..39101)
                     /locus_tag="VQ548_000621"
     CDS             complement(38805..39101)
                     /locus_tag="VQ548_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2653523.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLISQGLTVTNVEGGMNAWPGQVE"
     gene            complement(39091..39252)
                     /locus_tag="VQ548_000622"
     CDS             complement(39091..39252)
                     /locus_tag="VQ548_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HET2653524.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTAQNLDGAYSLYKMV
                     NPEGVEYGN"
     gene            39322..40086
                     /locus_tag="VQ548_000623"
     CDS             39322..40086
                     /locus_tag="VQ548_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HET2653525.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLDEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            40699..42078
                     /locus_tag="VQ548_000624"
     CDS             40699..42078
                     /locus_tag="VQ548_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET2653526.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            42092..42757
                     /locus_tag="VQ548_000625"
     CDS             42092..42757
                     /locus_tag="VQ548_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HET2653527.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            42871..42966
                     /locus_tag="VQ548_000626"
                     /pseudo
     CDS             42871..42966
                     /locus_tag="VQ548_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            43112..43561
                     /locus_tag="VQ548_000627"
     CDS             43112..43561
                     /locus_tag="VQ548_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2653528.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDAFVTNFVYEKEGQSRKKSMSYESVLPVRQIFD"
     gene            43718..44128
                     /locus_tag="VQ548_000628"
     CDS             43718..44128
                     /locus_tag="VQ548_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HET2653529.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKRIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            44244..>45159
                     /gene="pavB"
                     /locus_tag="VQ548_000629"
     CDS             44244..>45159
                     /gene="pavB"
                     /locus_tag="VQ548_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HET2653530.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAV"
BASE COUNT        12582 a         8714 c        10653 g        13210 t
ORIGIN      
        1 aacatatata cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa gagtgttaga
       61 aaatgccgat aagggtctgc ataccaagag tggtgaggat gatggcaatc cagcagatgg
      121 ctccaagaag aatggatttt ccactggatt tgaccatagc gaccagattg gttttgagac
      181 cgatagcact catggccatg acaataagga atttagagag ttctttgaga ggggtaaaga
      241 aactactgga cacacctaga gaggtgagta gtgtagtgag gagagaggca aggataaagt
      301 aaaggataaa aagtgggaag acttttttca gttgtaggct ttgcttgttt tcttgttggc
      361 gactttgcca gtaggagaga aagagcgtga tagggataat agccaaagta cgtgtgagtt
      421 taacaatggt tgcagactcg agggtattgc tttggtaaag actgtcccaa gcgctggcgg
      481 cagccgttac agaggaagtg tcgttgaccg cagtccctgc aaagagggcg aagccttcat
      541 tggatagatg aagccaggtg ccgagggttg gaaagatgag cgcagccaag acattgaaga
      601 aaaagataac ggaaatggct tgggctactt ccttttcctt agcatcaata acgggcgctg
      661 tcgctgcaat ggcagaaccc ccacagatag aagaacctac tccaaccaag gtagccagtt
      721 ttgtatccag tgcaaagaaa cgctggaaga ggtaggcaat aatcagagct attgagatag
      781 tggacaggat gacagggagt gaagattggc caactgcgaa gacctgcgag atattgagac
      841 caaaaccaag caagacaacg gcatattgga gcaacttctt ggaactaaag gtcaaaccag
      901 catccagttg tttataggac gagagaaagg gatgtaggag catgcctatg aaaatggcaa
      961 aaacgggcgc gccaatcaca gggaagaatc ctcctaagta ccaagatacg atagaaatga
     1021 gaaggcaggc caagatacct gctccatttt ttgatagaaa tgacataaaa acctccaaat
     1081 aaaatctatt accattatag acctataaac aggaaaagta aaatagaaag tggaaagcta
     1141 ttctctaatg tatttttgcg gtcggggggc ttttgtagta taatagagat acgttttgaa
     1201 agtaggaggt atctatggac ttaactaagc gctttaataa acagttagat aaaattcaag
     1261 tttcgttgat tcgtcagttt gaccaggtta tttcggagat tcctggggtc ttgcgtttga
     1321 ccttggggga acctgatttt acaacgccag accatgtcaa ggaggcggcc aagcgagcga
     1381 ttgatcagaa ccaatcctac tatacaggga tgagtggtct gctgactcta cgtcaggcag
     1441 ccagtgactt tgttaaggaa aagtaccaac tggactatgc tcctgaaaat gaaattttgg
     1501 ttacaattgg ggcgacagag gctttatctg cgactttgac ggctattttg gaagagggag
     1561 acaaggtact tttgccagct cctgcttatc caggctatga accgattgtt aacttagttg
     1621 gggcagaaat tgttgagatt gatacgactg aaaatggttt tgtcttgact cctgagatgt
     1681 tggagaaggc cattttggag cagggtgata agctcaaggc ggttattctc aactatccag
     1741 ccaatccgac aggaattacc tacagtcgag agcagttaga ggccttggca gctgttttac
     1801 gcaagtacga aatttttgtt gtctgtgatg aggtttactc agaattgacc tacacaggcg
     1861 aagcccatgt gtctctagga acgatgttga gagaccaggc tattattatc aatggtttgt
     1921 ctaaatcgca tgccatgaca ggttggcgtt tggggctgat tttcgctcct gcggccttca
     1981 cagcccagtt aatcaagagt caccaatact tggtcactgc cgcaaatacc atggcgcaac
     2041 atgctgcggt agaagccttg acggctggta aaaatgatgc ggagcccatg aagaaggaat
     2101 atatccaacg tcgggactat atcatcgaaa aaatgactgc tcttggtttt gagattatca
     2161 aaccagacgg tgccttctat atttttgcta aaattccagc gggctacaat caagactcct
     2221 ttgcttttct gaaggatttt gctcagaaga aggccgttgc ctttatccct ggtgcagcct
     2281 ttggacgtta cggggaaggc tacgtccgcc tatcttatgc agccagcatg gagactatca
     2341 aagaagccat gaaacgactt gaggagtaca tgagagaagc atgattcagt ctatcacgag
     2401 tcaaggcttg gtgctttaca atcgcaattt tcgtgaggat gacaagctcg tcaaaatttt
     2461 tacagagcag gttggcaaac gcatgttttt tgtcaaacac gctggtcagt ctaagctggc
     2521 gcctgttatt cagcccttgg tgctggcacg atttctcttg cgaatcaatg atgacggact
     2581 cagttacatc gaagactatc atgaggtcat gacttttccc aagattaata gtgacctctt
     2641 tgtcatggcc tatgcgacct atgtggcagc tcttgcagat gctagtttgc aggacaatca
     2701 gcaggatgct cccttgtttg cttttttgca aaagactttg gagttgatgg aagcaggctt
     2761 ggattatcag gttttgacca atatttttga aattcaaatt ttgactcgat ttggaatcag
     2821 cctcaatttt aatgagtgtg tcttctgcca tcgggttggt caggcttttg acttttcttt
     2881 caaatatgga gcctgcctct gtccagagca ttatcatgag gataagagac gttgtcatct
     2941 caatcccaat atcccctatc tgctcaatca atttcaagct attgattttg agactttgga
     3001 gaccatttcg ctcaagcctg gaatcaagca agagctacgc caatttatgg atcaattata
     3061 tgaagagtac gttgggattc acctaaaatc aaagaaattt attgattccc tagcagactg
     3121 gggacaatta ctaaaagagg aaaagaaatg aaaaaaatcg cagtagatgc catggggggc
     3181 gattacgcac ctcaggccat tgttgagggt gtcaatcaag ccctatctga cttttcagat
     3241 atcgaggttc aactttacgg agatgaagct aaaatcaagc aatatctgac agcgacagag
     3301 cgcgtcagca ttatccatac ggatgagaag attgattcgg atgatgaacc tacgagagct
     3361 attaggaata agaaaaatgc cagtatggta ttggcagcca aggctgtcaa agatggtgaa
     3421 gcagacgctg tcctttcggc tgggaataca ggtgccttgt tggcagcagg attcttcatc
     3481 gtgggtcgta tcaagaatat cgaccgtcct ggactcatgt ctaccttgcc taccgttgat
     3541 ggaaaaggtt ttgacatgct agaccttggt gccaatgcag aaaatacagc ccagcacctc
     3601 catcaatatg cggttctagg ttccttctat gctaaaaatg tccgtggcat tgcgcaacca
     3661 cgcgttggtt tgctcaacaa cggaacagag agtagcaagg gcgacccgct tcgtaaggaa
     3721 acttatgaat tactggcggc tgatgaaagt ttgaacttta tcggaaacgt ggaagcgcgt
     3781 gatttgatga atggcgttgc agatgttgtt gtggcagatg gtttcacggg aaacgctgtg
     3841 ctcaaatcca tcgaagggac agctatggga atcatgggct tgctcaagac agctattaca
     3901 ggtggtggtc ttcgagcgaa actaggtgcc ctccttctca aggacagcct cagaggtttg
     3961 aaaaaacagc tcaattattc agatgttggt ggagcggtct tgtttggtgt taaggcacct
     4021 gttgtcaaga ctcatggctc aagcgatgcc aaggctgttt atagtacgat tcgtcagatc
     4081 cgtaccatgc tagaaacaga cgtggttgcc cagactgcgc gtgaattttc aggagaataa
     4141 aagagatgac agaaaaagaa atttttgacc gtattgtgac cattatccaa gagcgacagg
     4201 gagaggactt tgtcgtgaca gaatccttga gtctgaaaga cgatttggat gcggattctg
     4261 ttgacttgat ggagtttatc ttgactctgg aagatgaatt tagtatcgaa atcagcgatg
     4321 aggaaattga ccaactccaa agtgtaggag atgtggttaa aatcattcaa ggaaaatagc
     4381 aatcggagtt ccaagtcaac ggaagtagat ggtttttaga aatgagaaat atcggacaag
     4441 ctggtaaaat cttggctgac agtggttatc aagggctcat gaagatatat cctcaagcac
     4501 aaacttccac gtaaatccag caaactcaag ccgctaacag ttgaagataa agcctgtaat
     4561 catgcgctat ctaaggagag aagcaaggtt gagaatatct ttgccaaagt aaaaacgttt
     4621 aaaatgtttt caacaaccta tcgaaatcat cgtaaacgct tcggattacg aatgaatttg
     4681 attgctggta ttatcaatca tgaactagga ttctagtttt gcaggaagtc taatagtaaa
     4741 aaagtgatta gaaaacatct tttttaaaaa tagagatgat tttgaaacaa aaaagctaat
     4801 tcaagacgtt tcgatgccaa ttcaagattt ggatgaaaaa aattaataga tactgttata
     4861 ctaaacttgt caagtttgta acaagacaaa tattaaaaat aaaaaagagg tattcgttat
     4921 gaatacaaaa aagatgtcac aatttgaaat tatggatact gagatgcttg cttgcgttga
     4981 aggtggcgga tgcaattggg gagattttgc caaagcaggt gttggaggag gagcagtacg
     5041 aggtcttcag ctaggaatta aaacaagaac atggcaaggt gcagcaactg gtgctgcggg
     5101 aggagctata cttggaggtg tggcctatgc agcgacatgt tggtggtaat tatggatttt
     5161 aaaagtttta ttattggttt agtagttggt atatttggtc cttatatgga tgatttaatt
     5221 agaaaaaaat ttttaaagtc ttcggagaag aaaacagaaa aatctgttaa aaaataatca
     5281 aaactataaa tgatgaatct gaatcaaaat tattttgcgc atgtaaagag gagtcttata
     5341 gtaacgagtc aaaaaaggag taactatgaa tcgtaattta gaacggtgtt atctattctg
     5401 actaggaata gatcatacca gaggtagctt agaaatagca gggacattag aaattgaagt
     5461 aataaatagg atgtcgtaag tgttactatc aatgatttat ttgtttcaag cttgcctagg
     5521 gtgacagtaa aaaatcaatt tcctttcaat agcatatttt tagtgggcag gactcttgtt
     5581 ctgcctattt ttttatccaa aaagtgcagt tgggagggag ataggctcat ttgggaagga
     5641 agtccagttt ttgtttagtg attggggtaa gatagttgtt atcagatgag tttatactct
     5701 tcgaaaatca aattcaaacc acgtcaacgt cgccttgccg tatatatgtg actgacttcg
     5761 tcagtcctat ctacaacctc aaaacagtgt tttgagcagc ctgcggctag tttcctagtt
     5821 tgctctttga ttttcattga gtattaggga aaaggagatg aatatgaaat ttgggaaacg
     5881 tcactatcgt ccgcaagtgg atcagatgga ctgcggtgta gcttcattag ccatggtttt
     5941 tggctactat ggtagttatt attttttggc tcacttgcga gaattggcta agacgaccat
     6001 ggatgggacg acggctttgg gcttggtcaa ggtggcagag gagattggtt ttgagacgcg
     6061 agccattaag gcggatatga cgctttttga cttgccggat ttgacttttc cttttgttgc
     6121 ccatgtgctt aaggaaggga aattgctcca ctactatgtg gtgactgggc aggataagga
     6181 tagcattcat attgccgatc cagatcccgg ggtgaagttg actaaactgc cacgtgagcg
     6241 ttttgaggaa gaatggacag gagtgactct ttttatggca cctagtccag actataagcc
     6301 ttataaggaa caaaaaaatg gtctgctctc ttttatccct atattagtga agcagcgtgg
     6361 cttgattgcc aatatcgttt tggcaacact cttggtaacc gggattaaca ttgtgggttc
     6421 ttattatctg cagtctatca ttgataccta tgtgccagat cagatgcgtt cgacactagg
     6481 gattatttct attgggctag tcatcgtcta catcctccag caaatcttgt cttacgctca
     6541 ggagtatctc ttgcttgttt tggggcaacg cttgtcgatt gacgtgattt tgtcctatat
     6601 caagcatgtt tttcacctcc ctatgtcctt ctttgcgaca cgcaggacag gggagatcgt
     6661 gtctcgtttt acagatgcta acagtatcat cgatgcgctg gcttcgacca tcctttcgat
     6721 tttcctagat gtgtcaacgg ttgtcattat ttcccttgtt ctattttcac aaaataccaa
     6781 tctctttttc atgactttat tggcgcttcc tatctacaca gtgattatct ttgcctttat
     6841 gaagccgttt gaaaagatga atcgggatac catggaagcc aatgcggttc tgtcttcttc
     6901 tatcattgag gacatcaacg gtattgagac tatcaagtcc ttgaccagtg aaagtcagcg
     6961 ttaccaaaaa attgacaagg aatttgtgga ttatctgaag aaatccttta cctatagtcg
     7021 agcagagagt cagcaaaagg ctctgaaaaa ggttgcccat ctcttgctta atgtcggcat
     7081 tctctggatg ggggctgttc tggtcatgga tggcaagatg agtttggggc agttgattac
     7141 ctataatacc ttgctggttt actttaccaa tcctttggaa aatatcatca atctgcaaac
     7201 caagcttcag acagcgcagg ttgccaataa ccgtctaaat gaagtgtatc tagtagcttc
     7261 tgagtttgag gagaagaaaa cagttgagga tttgagcttg atgaagggag atatgacctt
     7321 caagcaggtt cattacaagt atggctatgg tcgagacgtc ttgtcggata tcaatttaac
     7381 cgttccccaa gggtctaagg tggcttttgt ggggatttca gggtcaggta agacgacttt
     7441 ggccaagatg atggttaatt tttacgaccc aagtcaaggg gagattagtc tgggtggtgt
     7501 caatctcaat cagattgata aaaaagccct gcgccagtac atcaactatc tgcctcaaca
     7561 gccctatgtc tttaacggaa cgattttgga gaatcttctt ttgggagcca aggaggggac
     7621 gacacaggaa gatatcttac gggcggtcga attggcagag attcgagagg atatcgagcg
     7681 catgccactg aattatcaga cagaattgac ttcggatggg gcagggattt caggtggtca
     7741 acgtcagaga atcgctttgg cgcgtgctct cttgacagat gcgccggtct tgattttgga
     7801 tgaggcgact agcagtttgg atattttgac agagaagcgg attgtcgata atctcatggc
     7861 tttggacaag accttgattt tcattgctca ccgcttgact attgctgagc ggacagagaa
     7921 ggtggttgtc ttggatcagg gcaagattgt cgaagaagga aagcatgctg atttgcttgc
     7981 acagggaggc ttttacgccc atttggtcaa tagctagaaa gaggagagga tgaaaccaga
     8041 atttttagaa agtgcggagt tttataatcg tcgttaccat aatttttcca gtagtgtgat
     8101 tgtacccatg gcccttctgc tcgtgttttt acttggcttt gcaactgttg cagagaagga
     8161 gatgagtttg tccactagag ctactgtcga acccagtcgt atccttgcaa atatccagtc
     8221 aactagcaac aatcgtattc ttgtcaatca tttggaagaa aataagctgg ttaagaaggg
     8281 ggatctcttg gttcaatacc aagaaggggc agagggtgtc caagcggagt cctatgccag
     8341 tcagttggac atgctaaagg atcaaaaaaa gcaattggag tatctgcaaa agagcctgca
     8401 agaaggggag aaccactttc cagaggagga taagtttggc taccaagcca cctttcgcga
     8461 ctacatcagt caagcaggca gtcttagggc tagtacatcg caacaaaatg agaccatcgc
     8521 gtcccagaat gcagcagcta gccaaaccca agccgaaatc ggcaacctca tcagtcaaac
     8581 agaggctaaa attcgcgatt accagacagc taagtcagct atggaaacag gtgcttcctt
     8641 ggccagtcag aatctagcct actctcttta ccagtcctac aagtctcagg gcgaggaaaa
     8701 tccccaaact aaggttcagg cagttgcaca ggttgaagca cagatttctc agttagaatc
     8761 tagtcttgct acttaccgtg tccagtatgc aggttcaggt acccagcaag cctatgcgtc
     8821 agggttaagc agtcaattgg aatcccttaa atcccaacat ttggcaaagg ttggtcagga
     8881 attgaccctt ctagcccaga aaatcttgga ggcagagtca ggtaagaagg tacagggaaa
     8941 tcttttagac aaggggaaaa ttacggcgag tgaggatggg gtgcttcatc ttaatcctga
     9001 gaccagtgat tctagcatgg ttgcagaagg tgccctacta gcccaacttt atccatcttt
     9061 ggaaagagaa gggaaagcca aactcacagc ctatctaagt tcaaaagatg tagcaagaat
     9121 caaggtcggt gattctgttc gctatactac gactcatgat gccgggaatc aacttttcct
     9181 agattctact attacaagta ttgatgcgac agctactaag actgagaaag ggaatttctt
     9241 taaaatcgag gcggagacta atctaacttc ggagcaggct gaaaaactta ggtacggggt
     9301 ggaaggccgc ttgcagatga ttacgggcaa gaaaagttat ctacgttatt atttggatca
     9361 atttttgaac aaagagtaat gttcgtgttt ttagagttaa ataattttta aactgtgaga
     9421 aagattcttc ttgcagtttt ttctttacaa tttttaaaaa aacatctgct atttattcgg
     9481 ttaaattctt gtgttttttg gttttttgtg gtaaaatgtg ctcaagtaat acgaaaggcg
     9541 aactttaaaa tgtcaaaaca attgatctat tcgggaaaag ctaaagatat ctatacaact
     9601 gaggatgaaa atcttattat ttcaacttac aaggaccagg cgactgcttt caacggtgtc
     9661 aagaaggagc agattgcagg taagggagtc ttgaataatc agatctcatc ttttattttt
     9721 gagaaattaa atgcggctgg tgtggcgact cactttgtgg agaaactttc agacacggaa
     9781 caactcaata aaaaggttaa gattattcct ttggaagtcg tgctccgcaa ctatactgct
     9841 ggttcctttt caaaacgttt tggtgtggat gagggaatcg ccttggagac tccgattgtc
     9901 gaattttact acaaaaatga tgatttggat gatccattta tcaatgatga gcatgtgaaa
     9961 ttcctacaga ttgcgggtga ccagcagatt gcctacttga aggaagaaac gcgtcgtatc
    10021 aatgaactat tgaaagtctg gtttgctgag attgggctta aattgattga ctttaagcta
    10081 gagttcggtt ttgacaagga tggcaagatt atcttggcag acgaattttc accagataac
    10141 tgccgcttgt gggacgctga tggcaaccac atggataagg atgttttccg tagaggattg
    10201 ggagaactaa ccgacgttta tgagattgtt tgggaaaagt tgcaggaatt gaaataatct
    10261 gtttgcaacg gaaaaccttc gtctctcaac taaaaggact caggctgaaa aggtccccca
    10321 gaccttttca ctctgtagag aactaggtga actaacagat gtttacgaaa ttgtctggga
    10381 aaagttgcag ggtttaaaat aacaacctca aggctgtttg ggaatattgc aagagctgaa
    10441 ataaaggaat aagaattgat ggataaacgt atttttgttg aaaaaaaggc tgattttcag
    10501 gtcaagtcag agagtttggt tagagagctc cagcacaact tgggactgtc aagcttgaaa
    10561 agtattcgta ttgtgcaagt atatgatgta tttgacttgg ctgaggactt gtttgcacct
    10621 gcagagaagc acattttctc tgagcaggga accgaccatg ttttagatga agtatctgtg
    10681 caggcggatc ttgctaacta tgctttcttt gccattgaaa gtctgccagg gcagtttgac
    10741 cagcgtgcag cttcgtcaca ggaagccttg cttttgttgg gaagttcgag tgacgtgaca
    10801 gtcaacacag cccaacttta cttggtgaat aaagatattg atgcgactga gttggaagct
    10861 gtcaaaaact acctgctcaa tccagttgat tctcgtttca aggatatcac gacagggatt
    10921 gccaagcagg agttttcaga gtcagacaag accattccaa aattgacttt ctttgaaagc
    10981 tatacagcag aagactttgc tcgctacaag gccgagcaag ggatggccat ggaagtggat
    11041 gatttgctct ttatccaaga ctactttaag tcaatcgggc gcgtgccaac tgagactgaa
    11101 ctcaaggttt tggacactta ctggtctgac cactgccgtc atacgacttt tgagacagag
    11161 ttgaaacaca tcgacttttc agcttctaaa tttcaaaagc aattgcagtc aacctatgac
    11221 aagtatattg ccatgcgcga ggagttaggt cggtctgaaa aaccacaaac cttgatggat
    11281 atggcgacta ttttcggtcg ttatgagcgt gctaacggac gattggatga tatggaagtc
    11341 tctgacgaaa tcaatgcctg ctcagttgaa attgaagtgg atgttgatgg tgtcaaggaa
    11401 ccttggctcc tcatgtttaa aaatgaaacc cacaaccatc caacagaaat tgagccattt
    11461 ggtggagcgg ctacctgtat cggtggagct attcgtgatc cgttgtcagg ccgttcctat
    11521 gtttaccaag ccatgcgtat ttcaggtgct ggtgatatta cagcaccgat ttcggaaact
    11581 cgtgctggga aattgccaca acaagtcatt tctaaaacag cagctcatgg ttattcttca
    11641 tatggtaacc agattgggct tgccacaacc tacgttcgtg aatacttcca cccaggcttt
    11701 gtagctaaac gtatggaact tggtgccgtt gttggtgcgg ctcccaaggg caatgttgtc
    11761 cgtgaaaaac ctgaagcagg tgatgtgatc atccttctcg gaggcaaaac aggtcgtgat
    11821 ggtgtcggtg gtgcgacggg ctcttctaag gttcaaacag ttgagtctgt agagactgct
    11881 ggtgctgagg ttcaaaaagg aaatgccatc gaagaacgca agattcagcg cctcttccgt
    11941 aatggcaatg tcactcgtct gatcaagaag tccaatgact ttggggcagg cggcgtctgt
    12001 gtggctatcg gtgaattggc agacggtctt gaaatcgacc tcaacaaggt gcctcttaaa
    12061 taccagggct tgaatggtac agaaattgcc atctctgaat cacaagaacg gatggcggtc
    12121 gtggttcgtc ctgaagatgt ggataccttc gttgccgaat gtaacaaaga aaatattgat
    12181 gctgttgtgg tggcgacagt aactgaaaaa ccaaatcttg tcatgcactg gaatggtgag
    12241 acaatcgttg acttggagcg tcgtttcctt gacaccaatg gtgtgcgcgt ggttgtcgat
    12301 gccaaagttg tggacaagga tgtcaaactc ccagaagagc gtcaaacatc tgctgaaaca
    12361 ctggaatcag atacccttac ggttctatct gacctcaacc atgcaagtca aaaaggatta
    12421 cagactatct ttgactgctc tgttggacgc tcaacggtta atcacccact tggtggtcgt
    12481 taccaactca caccaactga ggcatctgtg cagaaattgc cagttcaaca cggtgtgact
    12541 catactgcgt cggtcattgc tcaaggtttc aacccatatg tagctgaatg gtctccatac
    12601 cacggtgctg cttatgcggt tatcgaagca actgctcgtt tggtggctgc tggtgccaac
    12661 tggtctaagg ctcgtttctc ttaccaagaa tatttcgagc ggatggacaa gcaagcagag
    12721 cgtttcggtc agccagtagc tgctcttcta ggttctattg aagcacaaat tcagcttggc
    12781 ttgccatcta tcggtggtaa ggactccatg tctggtacct ttgaagaatt gaccgttccg
    12841 ccaaccttgg ttgcctttgg ggtgacgacg gcagatagcc gtaaggtgct ctctccagaa
    12901 tttaaagctg ttggggaaaa tatctactac atcccaggtc aagccctctc tgcagagatt
    12961 gattttgact tgattaagaa aaattttgct cagtttgaag caagccaagc tgaccataaa
    13021 gtgacgtctg catcagctgt caaatacggt ggtgtagttg aaagtttggc tcttgctacc
    13081 tttggaaact atattggtgc agaggtgacc ttgcctgaac ttaaaacagc tttgacagct
    13141 caattaggcg gctttgtctt cacatctcct gaagaaattg ctggagtaga gaagattgga
    13201 caaacgaaag cagactttac actgactgtc aacggtgtga agctagatgg acacaagctt
    13261 gacagtgcat ttcaagggac attggaagaa gtttacccaa cagaatttac ccaagcgaaa
    13321 gaactagaag aagtaccagc tgtggcatca gatgttgtga ttaaagccaa agaaaaggtt
    13381 gaaaaacctg tggtttacat cccagtcttt ccaggaacca actcagaata tgattcagct
    13441 aaggccttcg aaaaagaagg tgcagaggtc aatttggtgc cattcgtgac cttgaatgaa
    13501 gaagctattg tcaagtcagt tgaaactatg gttgacaata tcgacaagac taatattctc
    13561 ttctttgccg gtggattctc ggctgcggat gaaccagatg gttcagctaa gtttatcgtc
    13621 aatatcctgc ttaatgaaaa agtgcgtgtg gctattgata gctttatcgc ccgtggtggc
    13681 ttgattatcg gtatttgtaa tggattccaa gccttagtca aatcgggtct cctaccatac
    13741 ggaaactttg aagatgctaa cagtactagt ccaaccctct tctacaatga tgccaaccaa
    13801 cacgtgacca agatggtgga aactcgcatt gccaatacca actcaccatg gttggctggt
    13861 gtgcaagtgg gcgatatcca cgctattcct gtttcgcacg gtgaagggaa gtttgtcgtg
    13921 acggctgagg aatttgcaga gctccgtgac aatggacaaa ttttcagcca atacgttgac
    13981 tttaacggta aaccaagtat ggattctaag tacaatccga atggttctgt ccatgccatc
    14041 gaaggaatta ccagcaagaa tggtcaaatc atcggtaaga tgggccactc agaacgttat
    14101 gaggatggtc ttttccaaaa tatcccaggc aataaagacc aacacctgtt cgcatcagcg
    14161 gttaaacatt tcactggaaa ataagactta cagattttct aatagatagt atcagtaatg
    14221 taaaagtcat gtaaatctag ctcttgatga ttacaaatga aaattaggta taaaaaatga
    14281 catacgaagt aaaatctctt aatgaagaat gtggtgtttt cggtatttgg ggacatccag
    14341 atgctgctaa gttgacctat tttggactcc acagtcttca acaccgtggt caggaggggg
    14401 caggaatcct ctccaatgat caaggacaac tgaagcgcca tcgtgacatg gggcttttat
    14461 cagaagtttt cagaaatcca gccaatttgg ataaattgac aggagctggt gcgattgggc
    14521 atgtgcgtta tgcgactgct ggcgaagctt ctgttgataa catccagccc ttcctcttcc
    14581 gttttcacga tatgcagttt ggcttggctc ataatggaaa tctgaccaat gcagcctctc
    14641 tcaagaaaga actggaacaa agaggagcaa ttttcagcgc gacttcggac tctgaaatct
    14701 tggctcacct cattcgtcgt agtcataatc ctagcctgat gggcaaaatc aaggaagcgc
    14761 tcagccttgt caaaggtggt tttgcctata tcttgctgtt tgaggacaag ttgattgcgg
    14821 ctcttgaccc taatggcttt cgtccgcttt ctatcgggaa aatggccaac ggagcggtgg
    14881 ttgtttcctc tgaaacctgt gcttttgagg tcattggtgc cgagtggatt cgtgatttga
    14941 agccaggtga gattgtgatc attgatgacg agggcattca gtatgacagc tatacagatg
    15001 atactcagtt ggcgatttgt tctatggagt atatctactt tgctcgccct gattctaata
    15061 tccacggtgt caatgtccat acggcacgta agagaatggg agcgcaattg gcgcgagaat
    15121 ttaagcatga ggcagatatt gtagttggtg tgcccaattc ttccctaagc gcggctatgg
    15181 gatttgcgga agaatcaggc ttaccaaatg aaatgggtct gatcaaaaac caatacaccc
    15241 agcgaacttt tatccaaccg actcaagaat tgcgggagca aggagtgcgg atgaaactgt
    15301 ctgctgtttc gggtgttgtc aaaggcaaac gtgtggtcat ggtggatgat tccattgtac
    15361 gtggaacaac ctctcgtcgt atcgttcagc tcttgaaaga agcgggtgcg actgaggttc
    15421 acgttgccat tggaagtcct gcactagcgt atccatgttt ctacgggatt gatatccaga
    15481 cccgtcagga gctgattgca gccaatcata cggtcgaaga aactcgccaa atcattggtg
    15541 cggacagtct gacttatctt tcaattgatg gcttgattga gtcgattggt atcgaaacag
    15601 atgcgccgaa cggtggtctc tgtgtcgctt actttgacgg tgactaccca acgcctctct
    15661 atgactacga agaagactat cgtagaagtt tggaagaaaa gaccagtttt tacaagtagg
    15721 cgacagattc tccattaaag aaaaggaaaa aacaaatgac aaataaaaat gcatatgccc
    15781 agtcgggtgt ggatgttgaa gcgggttatg aagttgttga acggattaaa aagcacgtgg
    15841 cccgtacgga gcgtgcaggt gtcatgggag ctcttggtgg ctttggtggt atgtttgacc
    15901 tttccaagac tggggttaaa gaacccgtct tgatttcagg gactgacggt gtcggaacca
    15961 agctcatgtt ggctatcaag tacgacaagc acgataccat cgggcaggac tgtgtggcca
    16021 tgtgtgtcaa cgacatcatt gctgcaggtg cggaacccct ctattttctc gactacgtag
    16081 cgacagggaa gaatgaacca gctaagctag aacaagtggt tgctggtgtg gcagaaggtt
    16141 gtgtgcaggc tggtgctgcc ctcatcggtg gggaaacggc tgaaatgccg ggcatgtacg
    16201 gcgaagacga ctatgacttg gctggttttg cggtcggtgt ggctgaaaaa tctcaaatca
    16261 ttgacggttc aaaggtggta gagggagatg ttcttctcgg acttgcttca agtgggattc
    16321 actcaaatgg ttactctttg gttcgtcgtg tctttgcgga ttacacaggt gaggaagtcc
    16381 taccagaatt ggaaggcaag aaacttaagg aagttctact tgagccgact cgtatctatg
    16441 tcaaggctgt cttgccgctc atcaaagaag agttggtcaa cggcattgcc cacatcacag
    16501 gtggtggctt tatcgaaaat gtccctcgta tgtttgcaga tgacctagct gctgaaattg
    16561 atgaaagcaa agttccagtg cttccaattt tcaaagccct tgaaaaatat ggtcagatta
    16621 aacacgaaga aatgtttgaa atcttcaata tgggtgtggg acttatgttg gcggtcagcc
    16681 ctgaaaatgt agagcgtgta aaagaattgt tggatgaagc agtctatgaa attggtcgca
    16741 tcgtcaagaa agaaaacgaa agtgtcatta tcaaatgaaa aaaatagcgg tttttgcctc
    16801 tggtaatggc tcaaattttc aggtgattgc cgaagaattt ccagtggagt ttgtcttttc
    16861 agaccatcgt gatgcctatg tgcttgagcg tgcaaagcag ctcggcgttc tgtcctatgc
    16921 ttttgaactc aaggagtttg agagcaaggc agactacgaa gcagcccttg tcgaactctt
    16981 ggaagaacac cagattgcct tggtttgcct agcaggctac atgaaaatcg ttggaccaac
    17041 cttattgtcg gcttatgaag gtcggattgt caacattcat ccagcctact tgccagaatt
    17101 tccaggagct catgggattg aggatgcttg gaatgctggc gtgggtcagt ctggtgtgac
    17161 cattcactgg gtggattcgg gtgtggatac aggccaggtc atcaaacagg ttcgtgtgcc
    17221 acgactagct gatgatacca ttgacagatt tgaagctcgc atccatgaag cagagtacag
    17281 gttgtatccg gaagtagtga aggctctatt tacagattga ctttttgatg attcatatga
    17341 tatctttgat tttaaattgg agtcagtgtt tgttgaagac ggcttcaaac ggaggtattt
    17401 gtaatgttag aatctaaaaa aacaactcga tatgtatttt atgtctatct gatgttatta
    17461 acttggggaa tcttatttaa gtttgaaaca aatcctgaat ttatagcatt tttcttagct
    17521 ccaaggtata tcaattggat tccattttca gaaccactaa tagtcgatgg aaaaattgtt
    17581 tttgctgaaa tgttatttaa tctgattttc tttattccat taggtgtttg tttccctttg
    17641 ataaaaacta atttatctag tttaagaata gtcgggacag gtttcttgat tagtttattg
    17701 tttgagtgct tacagtatat tttagcaata ggtataacag atataacgga tttgacttta
    17761 aatacgctag gtgtctgtgt aggcttactg atttatcaaa tttttataag agtgttcaaa
    17821 tcacagacta gaaaatggat caatatctta ggtatgctta gccttggttt tgcttatctt
    17881 gttttactgt tactgcattt aattggtgtt taactaatga ttaaaaagga gaatataatg
    17941 actaaacgcg tcttaatcag cgtctcagac aaagcggaca ttgttgaatt tgcccaagaa
    18001 ctcaaaaaac ttggttggga gattatctcg acaggtggaa ctaaggttgc ccttgataat
    18061 gctggggtgg ataccattgc tatcgatgat gtgactggtt tcccagaaat gatggacggt
    18121 cgtgtgaaga ccctccaccc aaatatccac ggagggcttc tcgctcgtcg tgacttggat
    18181 agccacttgg aagcggctaa ggacaacaag attgagctca ttgaccttgt ggtggtcaac
    18241 ctttacccat ttaaggaaac tatccttaaa ccagatgtga cttatgatga tgcagttgaa
    18301 aatatcgata ttggtgggcc atctatgctt cgttcagcag cgaaaaatca tgccagtgtt
    18361 acagttgtgg tagatcctgc tgactacgct gtggttttgg acgaattggc agcaaacggc
    18421 gaaacctctt atgaaactcg ccaacgttta gcagccaaag tatttcgtca cacagcggct
    18481 tatgacgcct tgattgcaga atacttcaca gctcaagtgg gtgaaaacaa gcctgaaaaa
    18541 ctcactttga cttatgacct caagcaacca atgcgttacg gtgagaatcc tcaacaagac
    18601 gcggactttt accagaaagc tttgcctaca gactactcca ttgcttcagc caaacagctc
    18661 aacgggaaag aattgtcatt taataatatc cgtgatgcag atgctgctat ccgtatcatc
    18721 cgtgacttca aagatagtcc aaccgttgtg gctctcaaac acatgaatcc atgtggaatt
    18781 ggtcaagctg atgacatcga gactgcttgg gactacgctt atgagtctga cccagtgtct
    18841 atctttggtg ggattgtcgt cctcaaccgt gaggtggatg ctgcgacagc tgagaagatg
    18901 cacggcgttt tcctcgaaat catcattgca ccaagctata cggatgaagc gctagccatt
    18961 ttgatcaata aaaagaaaaa cttgcgtatc cttgccttgc catttaatgc tcaagaggct
    19021 agcgaagtgg aagcagaata cacaggtgta gtcggtggac ttctcgtgca aaatcaagac
    19081 gtggtcaagg aaagcccagc tgactggcaa gtggtgacta aacgtcagcc aactgagaca
    19141 gaagcgactg ctcttgagtt cgcttggaag gctatcaagt acgtcaaatc aaatggtatt
    19201 atcgtgacca acgaccacat gacacttggt gttggtccag gtcaaaccaa ccgtgtggct
    19261 tctgttcgcc ttgccattga ccaagccaaa gatcgtctgg acggggcggt ccttgcttca
    19321 gatgccttct tcccatttgc ggataacgtg gaagaaatcg ccaaagcagg aattaaggcc
    19381 atcatccagc ctggtggctc tgtccgtgac caagaatcca tcgaagcagc ggataaatac
    19441 ggcttgacta tggtctttac aggtgtgaga cattttagac attaagaaga taaaagggaa
    19501 gaaaacagtt tctttccttt tttggcttaa aatgctaact gaaacaagat taaaacgaac
    19561 ttttttgata taatgttggt aaataattcg caaaagaggt tgaggaatga aactgcttgt
    19621 tgtcggttct ggtggtcgtg agcatgcgat tgctaaaaag ttacttgaat caaaagacgt
    19681 ggaaaaagtc tttgtagctc ctgggaatga tgggatgact ctggatggtt tggaattggt
    19741 aaatatctct atttccgaac attctaaatt gattgacttc gcaaagacca atgatgttgc
    19801 ttggaccttt atcggtccag atgatgccct tgctgctggt atcgtggatg attttaacca
    19861 agctgggctt aaggcctttg gtccgactag ggctgcagcg gagctggagt ggtccaagga
    19921 ttttgccaag gaaatcatgg tcaaatatgg tgtttcgaca gcagcctatg gcacattttc
    19981 agatttcgag gaagcaaagg cctatatcga aaagcatggt gcgcctatcg tagtcaaggc
    20041 ggatggcttg gcgcttggga agggtgtcgt cgtttctgag acggttgagc aagcggtcga
    20101 agccgctcat gagatgcttt tggacaataa atttggtgac tcaggtgcgc gcgtggttat
    20161 tgaggaattc tttgaaggag aggaattttc actctttgcc tttgtcaatg gtgataagtt
    20221 ctacatcatg ccaacggctc aggaccacaa acgtgcctat gatggcgaca aagggcctaa
    20281 cacgggtggt atgggtgcct atgcgccagt tccacactta ccacagagtg tagttgatac
    20341 agcggttgac accattgtca agccagttct agaagggatg attaaagaag gtcgccctta
    20401 tctgggagtt ctttacgcag ggcttatcct gacagctgat ggaccgaaag tcattgagtt
    20461 caacgctcgg ttcggagatc cagaaactca gattatcttg cctcgcttaa cctctgactt
    20521 tgctcaaaat atcacagata tcctggatag caaggagcca aatatcacgt ggacggacaa
    20581 gggtgtgact ctgggtgtgg ttgtcgcatc caagggctac ccgctaaatt attcaaaggg
    20641 tgttgagttg ccagtcaaaa ccgatggcga catcattacc tactatgcag gggctaagtt
    20701 tgcggaaaat agcagagcac tgctctcaaa cggcggacga gtttatatgc tcgttaccac
    20761 agcagatacc gtcaaagaag cccaagccag catctaccaa gaactatccc aacaaaaaat
    20821 agaaggactc ttctaccgaa cagatatcgg aagcaaggca attaagtaaa gatataagaa
    20881 taacgcgccg tagtcgccaa acacgataat ggtcgtcgtg gtgaaaagac cagaacagtg
    20941 aatgttctgg tcagggggaa acttggagac cgtaggctca aagtttagga atgaaaccga
    21001 aggtttgctt ccgcctccat cacctaagac cattatcaaa aagaaaaata aaaattcaca
    21061 aaatacgtta atgatcgtat ggtttgcgag cgttagcgag ctaatataga acaatcaccg
    21121 ccgttgtgaa agaacgattg gatgataatc caatcgttca gggaaattgg aagaccttgg
    21181 gtttccaatt taggcatgag acacctttgg tggctgctgc cgtccctcac aagctaaggt
    21241 gattgttgaa aaagaggaaa aaggagaaga aatgaaacca gtaatttcca tcatcatggg
    21301 ctcaaaatcc gactgggcaa ccatgcaaaa aacagcagaa gtcctagacc gcttcggtgt
    21361 agcctacgaa aagaaagttg tttccgcaca ccgcacacca gacctcatgt tcaaacatgc
    21421 agaagaagcc cgtagtcgtg gcatcaagat catcatcgca ggtgctggtg gcgcagcgca
    21481 tttgccaggc atggtagctg ccaaaacaac ccttccagtc attggtgtgc cagtcaagtc
    21541 tcgtgctctt agtggagtgg attcactcta ttctatcgtt cagatgccgg gtggggtgcc
    21601 tgttgcgacc atggctatcg gtgaagctgg agcgactaac gcagctctct ttgccctccg
    21661 tctcctctct gtagaagata agtccattgc ggatgcactt gccaactttg ctgaagaaca
    21721 aggaaaaatc gcagaggagt cgtcaaatga gctcatctaa aacaatcgga attatcggtg
    21781 gcggtcaact gggtcagatg atggccattt ctgctatcta catgggccac aaggttatcg
    21841 cgctggatcc tgcggcggat tgcccggcct ctcgcgtggc ggaaatcatt gtggcacctt
    21901 ataacgatgt ggacgccctc cgtcagttgg cagaccgttg cgatgtcctc acttatgagt
    21961 ttgaaaatgt cgacgctgac ggtttggatg ccgttatcaa ggatggacaa ctccctcaag
    22021 gaacagatct gctccgcatt tcgcaaaatc gtatttttga aaaggacttt ttgtcaaaca
    22081 aggctcaagt cactgtggca ccctacaagg tcgtgacttc tagcctagac ttggcagata
    22141 tcgacttgtc gaaaaactat gtcctcaaga ctgcgactgg tggctacgat ggtcatggac
    22201 aaaaggttat tcgttcagaa gcagacttgg aagcagccta tgcgctagca gactcagcag
    22261 actgcgtctt ggaagaattt gtcaactttg accttgagat ttctgtcatc gtgtcaggaa
    22321 atggcaagga ggtgacgttt ttcccagttc aggaaaatat ccaccgcaac aatatcctgt
    22381 ctaagaccat cgtaccagcc cgcatttctg aaagtctagc agacaaggct aaagctatgg
    22441 cagtgcgaat cgcagaacaa ctcaacttgt ctggaactct ctgtgtggaa atgtttgcga
    22501 ctgatgatga cgttattgtc aatgaaatcg ccccacgacc acataactct gggcactatt
    22561 ctattgaagc ctgtgatttc tctcagtttg acacccatat tctgggtgtt ctcggagcac
    22621 cattaccagt catcaaactc catgcgccag ccgttatgct taatgtcctc ggtcagcatg
    22681 tcgaggctgc tgagcaatat gtgacagaaa attcaagcgc ccacctccac atgtatggta
    22741 aaatagaagc gaagcacaac cgcaagatgg gacatgtgac cttgtttagt gatgtaccgg
    22801 atagtgtgga tgagcttggg gaagggattg atttttagga caagtctatg atacaaatta
    22861 tcgttaatac atttattgaa aaggataaga ctggagcagt tgttgaagtg ttgtatgcca
    22921 gtgctgacca agataaggta caagctaaat atgaagaact agctgcacaa taccccgaaa
    22981 attatttagc tatctatgat gtaccgctgg atacggattt gaatacacta gatcattacc
    23041 cgtctgtgtt tattgaaaaa gaggagtttg agtagaaatc ttggtttacc tagatagctt
    23101 attcccaaca gcttaagaag aaaggaaaaa ttaacacatg atcaaccgtt actctcgccc
    23161 tgagatggcg aatatttgga gtgaagaaaa taaataccgt gcttggcttg aggtggaaat
    23221 cctctctgac gaggcatggg ctgagttggg ggaaatccct aaggaagatg tggctttgat
    23281 tcgcaagaag gcggactttg acatcgaccg tattttggaa attgagcagg agacgcgcca
    23341 cgatgtggtg gctttcacgc gtgcggtttc tgagactctt ggtgaagagc gcaagtgggt
    23401 tcactatggg ttaacttcta ccgacgtggt ggatactgct tatggttacc tctacaagca
    23461 ggccaacgac atcatccgtc gtgaccttga aaacttcact aatatcatcg ctgacaaggc
    23521 caaggagcac aagttcacca tcatgatggg gcgtactcat ggtgtgcacg ctgagccgac
    23581 aacctttggt cttaaattgg caacttggta cagcgaaatg aaacgcaata tcgagcgttt
    23641 cgagcatgca gctgctggtg tagaagctgg taagatttct ggtgcggttg ggaactttgc
    23701 caatatccca ccatttgtag aggagtatgt ctgcgataaa cttggcatcc gtgcccaaga
    23761 aatctctaca caagtccttc ctcgtgacct tcacgctgag tactttgcgg ttcttgccag
    23821 cattgcgact tcaatcgaac gtatggcgac tgagattcgt ggtctacaaa aatctgagca
    23881 acgcgaagta gaagagttct ttgctaaagg gcaaaaaggg tcttcagcaa tgcctcacaa
    23941 acgcaaccca atcggttctg aaaatatgac tggtctggcg cgtgtcattc gtggtcacat
    24001 gattacggct tatgaaaacg tcgctctctg gcacgaacgc gatatttctc actcatcagc
    24061 tgagcgtatc atcacaccag atacgaccat tttgattgac tacatgctca accgttttgg
    24121 aaatatcgtc aagaacttga cagtcttccc agaaaatatg atccgaaaca tgaactcgac
    24181 ttttggtctt atctttagcc aacgggctat gttgacattg attgaaaaag gcatgacccg
    24241 tgagcaagcc tatgacttgg tgcaaccaaa aacagcctac tcttgggaca accaagtaga
    24301 ctttaaacca cttcttgagg cagattcaga agtaacatca cgtctcactc aagaagaaat
    24361 cgatgaaatc ttcaacccag tttattacac caaacgagtg gatgatatct ttgaacgtct
    24421 tggactaggt gattaattaa aaaataaaca gcgagcttca atctcgctgt ttatttttta
    24481 tcgaaaagac ttagtcttct tttcttttag tgagtccata ggctgctagt gtggccatga
    24541 gtcctgcgac tactagtcct gcagaatcgt gagttcctgt ttcaggaagt tttttctcta
    24601 ttaccacagg agctggatct tgaggaagag ctttgctttc ctcagcagga gcagttgatg
    24661 gagctggttg gcttgggatt tctagttttg gtttttcttc agcaatagcg gcttgtccgt
    24721 tttcatcgcc tacatgtgtt accatagttc cgacttcgac tatttgagta acggcttcct
    24781 gtgctacgac actatttaca agtgttttca cttccttacc atcggcagaa gtgctcacag
    24841 agtagaagtt gctacgatgt ccattgacgc ccttagtaat gacttgtgtt tttcctttga
    24901 gtaagagtgg attttcacga gtcactgtgg taaatggaat ttcttctttt tggatatcca
    24961 gtctaggttt tacctcagta gttggtgcaa gaccactttc atcacccttg tgagttacag
    25021 gagcgccaac ttcaaccact tggtttataa cttctttggt tacctggcta tcaaggactg
    25081 tttctgttgt ttttccattt tcagtgagta cagagatgta atgagttcgc tcacctttga
    25141 ctcctgctgt gataatattt tcctgaccag ctgggaggtt aggattttct ttcttgataa
    25201 cttcaaatgg aatttcttca gttcttgtga tgagttctgg tctggtttca acattggcag
    25261 ccacttcatt ttcatccagg cttcctgaat gagttgcagc tggtttgagg ccttgaagag
    25321 cggcttttag gttggctaca agtgtgtcaa gctcagcttg tttattacgg ttgaggttgt
    25381 aatttagagc tgttttagct gcgtcaaggg cctcaagact ttctttacta tatccttcta
    25441 agtttgtagg aattttagct aattcttcgc ggagagcatt ataattagca cggaagtagt
    25501 ctttgttgtg gtctgcaaag gcagtcatga gttcaaagat ttcctcttcc ttgtattcag
    25561 cgcttggtct atctgcccag attgaaagca tacttccgac tgttggaaga tctacttcag
    25621 gatatttggt agaagctagt tgattgaatg gtgtttttcc agtattctca atagctttct
    25681 tgaggaaacc accaccatct tctggttttt gaccaagaat gtagtaccag tcaccgttgg
    25741 tattcaagaa tttatagcct ttgcttgcta ggtattgagg tgatgcgagg ttatatcccc
    25801 accagccttt agaccagtaa gaaatcaaga catctttgtc aaactgaaca tcgtccttgt
    25861 cttcatagta gaagccatcg ttgaaggcca ttggttgaag ccctctttct ttggccatag
    25921 ctgcgagggt gttggcatat tcggcaaatt tgccatagag ttgataccac ttgaggtagt
    25981 accagccttg ggcactagtc gcatcgttgg cgtattcgtc agtaccaaag ttgaaaatct
    26041 ttgttttacc tgcaaagaag tccatgtatt taccgatgag ggcttttaca aagttcatcg
    26101 cttcttcgtt tttcaagtcc atagttgttt ttgaaacttt atcaaagtgg gcttgaggat
    26161 ttttaatacc taatttttcc atggcaacca gcatagcatc catgtgacct ggactgttaa
    26221 tagctgggat gagaccgatg tccttagatt tagcgtattc aattagctct gttacttctg
    26281 cctgtgttag tgcagtaccg tttggatcgt cgtagtaagc tttagttcct tcgataatag
    26341 cttttttaac gtcatcacta gcataggttt ttccgttggc agtaatggtc atatcatcga
    26401 gtagaaagcg aagtccgtca tttcctagaa ggagatggac atcagaatat ccgagctcac
    26461 tggccttgtc tacgatgcgt ttgagctggt tcagagtaaa gtatttgcgt ccagcatcga
    26521 ttgagattac cttgtttttg gcaagttttt caacctcacg tttagcttct tcttcttttt
    26581 gagcttcagg cgtgagggtc aagttgttga cagtttcttg aagtttagca atggcttgat
    26641 caatcgtatc ttgttgggca cggctaaggt tgctatcgag agagcgaata gctttttcag
    26701 cttcttttac ggccgcgacg ctttctgcag tataacggtt caggtctttt ggtacctcgt
    26761 taagtgtttg ctctgcagat tcataatcag ctgcgaagta ttcagcgttg gcatttgcaa
    26821 aatgacgcat gagtttgaag aggcgtgatg gtgaataacg tgcagatgga gtgtcagccc
    26881 aagcagctac catactaccg atgattggga tatcagctcc ttctgttttt ggtacagaag
    26941 tgattggtgt gtttttaata ccattgagcc cctgatcgag attgtaccag ccttggccat
    27001 cagcgtttcg tccaagaacg tagtaccaag catcattggt attaaggatt tggtgacctt
    27061 tttcagctag tagtttagaa gaagcgacat cgtagcctcc ccaaccacca gtccacatag
    27121 aaacgatgat gtctttgtca aaactaccaa agcttgtgtc gctattgtag tagataccgt
    27181 cgttaaaggc cattggtttg agaccgtgcg attttacaat acgagcgagg tcattggcgt
    27241 aggcaataaa tttttcatag ccttttacag ggtagccttc gtttggatag tatttatcag
    27301 cttgaagcac actccaacct ttagcatctg tcgcatcatt ggcatattca tcaagtccga
    27361 tgttgaagat ttcagtcttt ttcgcgaaat aagcagcata cttgtcgata agggcttttg
    27421 taaaagcgac agcttgttcg ttgtcaagat tgacagtacg ggctgattcc ttcccaaaat
    27481 agctaaagtt agggttttgg attcccaatt ctttcatggc attgagaatc gcatccatgt
    27541 gaccaggact atttactgtc ggaatgagac cgataccttt atctttggca tagttaatca
    27601 gatctgtcat ttgactttct gttaagtgat tgccgtttgg atcgttgtaa taatcatttg
    27661 tacctttttc aatggcgcgt ttgacatcgt cactggcata ggtcttgccg ttagctgtga
    27721 tgctcatatc gtccaacatg aaacggagtc catcatttcc gactaatagg tgtaaatcag
    27781 tgtagccata atgtttcgct ttatcgatga tttccttgag ctgttctggt gagaaatatt
    27841 tacgtccagc atcaatagaa acaattttct ttttcgctag tttttcattt acagttgcag
    27901 cacgttcctt tcctgcctct gtttccggtt tgtcatcctc tgctttcgct tcatcttttt
    27961 tagctggttt atccttgtca gtcttgtctg tatttgactc tttagaatca acctctttcg
    28021 cttcttcctt tttagggcta gcttcttctg cctttttatt agcagtttct ttttcagcag
    28081 aagttggagt taccacttct gctttatcac taggagttga actaacttcc tcttgtggtt
    28141 tttcttctgt ttttggaaga ctagctacct tatcagtagc tggagtttct gtttctacag
    28201 tttttggagc ttctggttga agctctgctt taggtgtttc ctcagtccga ttttcggatg
    28261 attgagggga atcagaaacc gtatggatgg tcggttggtt ttctgtagta gtaggagtaa
    28321 ctccatcggc tgcaacagtc tgtgcttgga aggcaaatcc aattagaaca gaagctgctc
    28381 ctacagcgta tttacgaata gaaaaacgct gttgtttttc atgtttcatt gcaaaacctc
    28441 ctgattgcat tgttatattg atagcgatta tataaatcaa cgcctttatt ttatttctta
    28501 tattaacgag agtcaagagg agatgacaaa aaactataat aagtataaaa aaatataaaa
    28561 tttaaactta agatttcaga ttggtcggaa aaaatacgta tatatatcta gtataatttt
    28621 tggttctatt tctataaaat attccacaaa ttatagaatt ttccaaaaat aggtaagcgc
    28681 tacctttttg gtgtggtata ataagcatag aaaaagccca agcgattagc tcaggctttc
    28741 ttcttagtga tcacggtcac atgagataaa tttaatcttg tagtaatcag atcgtttgta
    28801 agtttcactg tattctaaaa cttggccagt tgattcgagt ttggtgattt tagtttgtag
    28861 gacagtaggg aattgttcat cgactccgag gactgaagcc gcatgttctg gagttggaaa
    28921 gactatttcg ttgatttctt caaagtgttc atcattcatg tgaatgtggt agtctaactt
    28981 gaaacgatta tagatagaac tatagtattc aaggtttgga taatttgcgt tgatatattg
    29041 ttctgggatg taggatgtat ggtagatata aacgacaccg tttgattcgc ggatacgttc
    29101 aatcttgtag tagaattgat cgccgcgtag acccaatttt tccaagtaaa caagcttgtt
    29161 tccgcgttca attgaaagaa cagttacctt atcatcttta gcattgaaga gttcaatatc
    29221 tgaaaactct acaagcttgt gtttgcgtgc acgtgaaacg aaggttcctt ttccttgttg
    29281 gcggacaata tagccatctt tggcaaggtc gtttaaggcg cgaacaactg tgatagagct
    29341 gacatcgtac attgaaatga gttctgcttc agtgtaaaat ttatctccac tgctaaactg
    29401 cccagagatg attttatttt ttaattcgtc ttttatgtat tgatatttgg gaattgccat
    29461 atttttacct ctattttcct tctccatagg aaattttacc ataaaagcga aaaaaatagt
    29521 agtcttttga ataaaaaatt agaataatag tttgaaaaat taagcgatat agggattgct
    29581 catattttat caatgtattc tatacaaaat tattttaggt cccatattcc gaatttaaag
    29641 agcgtttgaa atgggtctaa aaatgtttga aactaattga atgtgtgtat aatagtaaaa
    29701 atgcagtaaa tatcccgaca atttctattg acaattcaaa cagattggtt tataattaat
    29761 ataacaacaa atgaaagcgc aaactttcgc ggtcggaagg tagttttatg acacgatttg
    29821 agatacgaga tgatttctat ctcgatggaa aatcatttaa gattttatct ggtgccattc
    29881 attattttag ggttcctcca gaggattggt atcattcgct ctataacttg aaggctcttg
    29941 gttttaatac ggtagagact tatgttgctt ggaatttaca cgagcctcgt gaaggtgagt
    30001 ttcattttga aggtgatctg gatttagaga aatttctcca aatagcgcag gatttgggtc
    30061 tctacgcaat tgtgcgtccg tctccattta tctgtgcgga atgggaattc ggtggcttac
    30121 cagcttggct cttgaccaag aacatgcgaa ttcgctcatc cgacccagta tatatcgagg
    30181 cagttggtcg ctactatgat cagttattgc caagactggt gcctcgtttg ttggacaatg
    30241 gtggcaatat tctcatgatg caggttgaaa atgagtatgg ttcttacgga gaagataagg
    30301 cttacctgag agcgattcga cagctaatgg aagagtgtgg cgtaacctgt cccctcttta
    30361 catcagatgg tccatggcga gctactctga aagctggaac cttaattgaa gaggacctct
    30421 ttgtaacagg aaactttggt tctaaggcac cttacaactt ttcgcagatg caggaattct
    30481 ttgatgaaca tggtaagaaa tggccactca tgtgtatgga gttctgggat ggttggttca
    30541 atcgctggaa agaaccgatt atcacacggg atcctaagga attggcagat gcagttcgag
    30601 aggttttgga acaaggctct atcaatcttt acatgttcca cggtggtaca aactttggtt
    30661 tcatgaatgg ttgctcagct cgaggaactt tggacctgcc acaagttacg tcttatgatt
    30721 acgatgccct tctggatgaa gaaggaaatc caactgctaa atatcttgca gtcaagaaga
    30781 tgatggcaac acatttttca gagtatccgc agttggaacc actctacaaa gagagtatgg
    30841 agttggatgc tattccacta gttgaaaaag tttctttgtt tgaaacctta gatagcttgt
    30901 caagtcctgt agaaagtctc tatcctcaaa agatggagga gctgggacaa agttatggct
    30961 acctacttta tcgaacagaa acaaactggg atgcagaaga agaaagactt cgtatcattg
    31021 atggtcgaga tagggcccag ctgtatgtcg atggtcagtg ggttaaaact caatatcaga
    31081 cagagattgg ggaagatatt ttttatcaag gtaaaaagaa agggctatct aggttagata
    31141 tcttgataga aaatatgggg cgtgtcaact atgggcataa gttcttagcg gatacgcaac
    31201 gtaagggaat tcggacaggg gtctgtaagg atctgcattt cttactaaac tggaaacact
    31261 atccactccc actagacaat cctgagaaaa ttgatttttc aaaaggatgg actcaaggac
    31321 aaccagcctt ttacgcttat gactttacag tcgaagagcc aaaagatact tacctagact
    31381 tgtctgagtt tggtaagggg gttgcctttg tcaatgggca gaatctagga cgtttttgga
    31441 acgttggccc aactctctca ctttatatcc ctcatagcta tctcaaggaa ggtgccaacc
    31501 gcatcattat ctttgaaaca gaaggtcaat ataaagaaga gattcattta actcgtaaac
    31561 ctacactaaa acatataaag ggggaaaact tatgacaatt gtaggatgcc gtattgatgg
    31621 acgtttgatc cacggacaag tagccaatct ttgggctgga aaactaaatg tttcacgcat
    31681 tatggttgta gacgacgaag ttgtcaacaa cgatattgaa aagagtggtt tgaaacttgc
    31741 gacaccacca ggtgtgaaat tgagtatttt gccagttgag aaagctgcag ccaatattct
    31801 tgctggtaaa tacgatagcc aacgtctctt tatcgtggct cgtaaaccag accgcttcct
    31861 tggtttggta gaagcaggtg taccacttga aacccttaat gttgggaata tgtctcaaac
    31921 accagaaaca cgttctatta cacgttctat caacgtagta gacaaggatg tggaagactt
    31981 ccacaaactg gcagaaaaag gtgttaaact tactgctcag atggttccaa atgatccaat
    32041 ttcagacttt ttgagcttat taaaatagga aaaaaatttt taggaggtca ttgttatgat
    32101 acaatggtgg caaattttac ttctcacttt gtactcagct tatcaaatct gtgatgagtt
    32161 gacgatcgtt tcatctgcag gttctcctgt atttgctggt ttcattactg gtttaatcat
    32221 gggagatgtg actactggtt tacttatcgg tggtaacttg caactgttcg ttcttggggt
    32281 tggtaccttc ggtggtgctt ctcgtatcga cgcaacttct ggtgcggttc ttgcgacagc
    32341 cttctctgtt tcacaaggaa ttgatgcacc gcttgccatt actacaatcg ctgtaccagt
    32401 agcagctctc ttgacttact tcgacgttct tggtcgtatg actactacct tcttcgctca
    32461 ccgtgtggat gctgcaatcg aacgctttga ctataaaggt attgaacgca actacttgct
    32521 tggtgcgatt ccgtgggctc tatctcgtgc ccttccagtc ttctttgccc ttgcttttgg
    32581 tggtgccttt gtacaatcag tagtagactt cgttgaagcc tacaaatggg ttgcagatgg
    32641 cttgacactc gcaggacgta tgcttccagg tcttggattt gcaatcttgc ttcgttacct
    32701 tccagttaaa cgtaaccttc actaccttgc tatgggattt ggtttgacag ctatgttgac
    32761 tgttctttac tcatatgtaa caggtcttgg tggcgctgtt gctggtatcg taggtactct
    32821 tcctgctgaa gttgctgaaa aaattggttt cgtgaacaac ttcaaaggtt tgtctatgat
    32881 tggtatttct atcgtaggta ttttccttgc agtgcttcac ttcaaaaata gccaaaaagt
    32941 agctgtagca gcaccttcta caccatcaga aagtggggaa atcgaagatg acgaattcta
    33001 attacaaact tacaaaagaa gattttaatc aaatcaacaa acgtagcttg tttactttcc
    33061 aattaggttg gaactacgaa cgtatgcaag cttctggtta cctttacatg atcttgcctc
    33121 agttgcgtaa aatgtatggt gatggaactc ctgaattgaa agaaatgatg aaagttcata
    33181 ctcaattctt caatacttca ccattcttcc ataccattat cgctggtttt gaccttgcca
    33241 tggaagaaaa agatggtgta ggttcaaaag acgctgttaa cggtatcaag acaggtttga
    33301 tgggaccatt cgctcctctt ggggatacaa tctttggttc acttgtacct gctatcatgg
    33361 ggtcagtcgc agcaactatg gctatcgctg gccaaccttg ggggatcttc ctttggattg
    33421 cagttgcagt agcgtatgac atcttccgtt ggaaacagtt ggaatttgct tacaaagaag
    33481 gggttaacct tatcaacaac atgcaaagta ccttgacagc tttgattgac gctgcatctg
    33541 tacttggtgt cttcatgatg ggtgctcttg tagcaacagt gattaacttt gaaatttctt
    33601 acaagttgcc aatcggtgaa aagatgattg atttccaaga catcttgaac caaatcttcc
    33661 cacgtttgct tccagcaatc tttactgcct ttatcttctg gttgcttggt aaaaaaggta
    33721 tgaactctac taaagctatc ggtattatta tcgtacttgc tttggctctt tctgcccttg
    33781 gtcactttgc acttggaatg taattcctta tgactaaatc attaattttg gtgagccatg
    33841 gtcgcttctg tgaggagctt agaggtagca cagaaatgat tatgggccca caagacaaca
    33901 tttacacagt agctcttctt ccagaagatg gcccagaaga atttactgct aaatttgaag
    33961 ctgttattga aggattggat gatttcctag tctttgcgga tcttctcggt gggacacctt
    34021 gtaatgtggt gagtcgcttg atcatggaag gtcgtgatat tgacctttac gcagggatga
    34081 atcttccaat ggtgattgaa tttatcaatg cgagccttac aggcgcagat gcggactaca
    34141 agagccgtgc tgcagaaagc attgtgaaag ttaatgacct gttagcgggc ttcgatgatg
    34201 acgaagatga ataatactct tcgaaaatct cttcaaacta cgtcaacgtc gccttgccgt
    34261 aggtatatgt tactgacttc gtcagtctta tccggcaacc tcaaaacggt gttttgagct
    34321 gacttcgtca gtcttatccg gcaacctcaa agcagtgctt tgagcagcct gcggctagtt
    34381 tcctacagat tttagttgga actcgattca attcatgtga caacgtgaaa atcgttagag
    34441 cattttatat agaatataca tgggaatgga gcttactccc attcccatat ttaatagaaa
    34501 aagaggaact caatgctaca ttatacaaaa gaagacttgc tcgaattggg tgcagaaatc
    34561 actacgcgtg aaatctacca acagcctgat gtatggagag aagcttttga attttatcaa
    34621 gcaaaacgtg aagaaattgc agcctttcta caagaaatcg ctgataaaca tgactatatt
    34681 aaggttatct tgacaggtgc tgggacttct gcttatgtgg gagatacctt gctaccttac
    34741 tttaaggaag tctatgacga acgcaaatgg aatttcaatg ctattgcgac aacagatatc
    34801 gttgccaaac cagcaaccta tttgaaaaaa gatgtggcaa ctgtccttgt gtcttttgct
    34861 cgtagtggga actcgcctga aagtgtggcg actgttgatt tggccaaatc cttggtggat
    34921 gagctttatc aagtgacgat tacttgtgca gcagatggta aattggctct tcaagctcac
    34981 ggtgatgacc gtaatctctt gctcttgcaa ccagctgtct ctaatgatgc tggatttgcc
    35041 atgacttcta gctttacgtc tatgatgttg acaactctct tggtctttga tcctacagaa
    35101 tttgctgtta agtctgaacg ttttgaagtt gtatctagtc ttgcccgtaa agttttagac
    35161 aaggcagaag atgtcaaaga gctcgttgat ttagacttta accgtgtcat ctatctaggc
    35221 gctggtcctt tctttggact tgctcatgaa gctcagctca agattttgga attaactgct
    35281 ggtcaagttg cgaccatgta tgaaagccca gttggcttcc gtcacggtcc aaaatctctt
    35341 atcaacgaca atacagttgt tttggtcttt ggtacaacga cggactacac tcgtaagtac
    35401 gacttggact tggttcgtga agttgctggt gaccagattg ctcgtcgtgt tgtgcttttg
    35461 agtgatcaag cttttggtct tgaaaatgtc aaagaagtgg tccttggttg tggcggtgtc
    35521 ttgaatgata tttaccgtgt cttcccttac atcgtttatg cccaactctt tgccctattg
    35581 acttcactca aggtagaaaa taaaccagat acaccgtctc ctacaggtac agtaaaccgt
    35641 gtagtacaag gtgtcataat tcacgaatat caaaagtaag acagtgttta tgaattcttg
    35701 acaagaggat ttgtaaatta tcagataaac catagattgt cagtacgctt tctatggttt
    35761 gtttgcttga gagaaatagt aaaaggagaa cagaatgaaa gcatacacag agcgtgtatt
    35821 tggaaatgtt gagggtgagg atgtcttggc ctatcgattt gagacagacg gtggctacca
    35881 acttgaggtt atgacttatg gtgcgactat cttgcgctat gtcgcacctg acaaggctgg
    35941 aaattttgcc aatgttatct tgggatttga tgactttgat agttatgtag gcaatagtcc
    36001 caagcatgga gcaagtgtag gtcctgtagc gggtcgtatt gcaggtgcga cctttgagct
    36061 caatggtaag acctatgacc ttgaggttaa taatgctagc aactgtaatc acagtggttc
    36121 aactggttgg gattccagct tgtttgaagt tgaagaagta agcgatcatg gcttgactct
    36181 ctacacagag cgtacagatg ggacaggagg gttccctgga aatctcaaga tttggatcag
    36241 ttatcacttg gaagaaactg gtgcctatga aatcagctac aaggtaacga ccgatcagga
    36301 tacgctggtc aatccaacca accacagcta tttcaacttg tctggtgatt tcacgcagac
    36361 gattgaccgt catgtcttcc aactaaacac agagggcatt tactcaatcg ctcctgacgg
    36421 tgttcctgcc aaaactccag aagccaaccg tgatgtggtc aaacacatct acaatggtgc
    36481 cttgttgaag gatatctttg cagaagaaga tgagcaaatc cagctggcat caggtttgga
    36541 tcatccattt gcccttcctg caggccatga caatgctgga ttcctttatg accaaaattc
    36601 aggtcgcttc ctgcttttca agacagaagc tccttgcttt gtggtctaca cagcaaactt
    36661 tgtggatgaa agtgtcatca taggaggtca gccaatgcta cagcacaatg ggattgctct
    36721 tgaagcgcaa gctttaccag atgccattca cagtgacctt aaaggccaag tcattcttaa
    36781 agctggtcaa accttcacca gtaagacacg ttatgaactt gttgtgaaat aaaaaaagct
    36841 ggtcaaaaag tctttaaaat taaaataacg catattgtca ggtgatgaaa agtttgataa
    36901 tatgcgtttt attatgaaat gatttacttt atattatcct gaaatggtgt tatttttgag
    36961 ttatctggct tgactttctt gatggaaatt atataatagt tgtaacaatg ataattacaa
    37021 ctagaaaaga ggaccattta tgacctatga atacaagagt cacatttatt tggcagagac
    37081 agctttaaat gtaaaggatt tggccagtca aacagccttt tatcagcaag ttattggttt
    37141 agaaatctta tctcaaactg agacagagtc cattctaggc cttggtggaa aagtcttggt
    37201 acagctgatt caagcacaag agagcggaga agtgagggaa tattatggtc tttaccattt
    37261 ggccattctc ttgcccacac gcaaggcttt agctgatgtc ttgaaacacc tgacagattt
    37321 acaaattcct cttgtcggcg gtgcagacca tggttacagt gaagctattt acttggaaga
    37381 tttggaggga aatggcattg aactctatcg agataagcca gtttccacat gggatattcg
    37441 agaagatgga cgcattatcg gagtgacaga ggctcttgcg gcgcaggaca tttatgagtt
    37501 gggggaaaga gtagagccct ttatcctggc agaaggtacg agaatggggc atattcatct
    37561 ttccgtcaag gatagtcgaa agtccagcca gttttatcaa aaggtgttag ggctagagga
    37621 taaattcagt gtgcctagcg ctagttggat tgcggctgga gattaccatc atcatttagc
    37681 agttaacgaa tggggaggaa aaggtctggc ttcgcgtaag caaggcttac caggtttagc
    37741 ctactatgtc atcgaagtcg cacacaaaaa agaactatta acgattgccc aacgagcaca
    37801 agaagttgac gcaccaatca aatggatgac atcgagccaa ttggaaatca cagactcaga
    37861 tggcatcgtg acccgtattc gtttagcaag gtaaaattag gaatttttaa taagttataa
    37921 gtattgctag tttgcttttt gaacggtctt tggtaacaga actgcgtgag ctggatgggc
    37981 gagaattttg acaaagaagc tgattagaga tataatgaag aaaaatcgag caaggaaaaa
    38041 gaaatgacaa attcaaagta tattacttgt ttgaaacgtt cagagggcca gttgtgtggg
    38101 attcaaaaga tgattgaagg agatcgtgac tgtgctgata ttgtgacgca actgacagca
    38161 gtgagatcta gtgtagagcg cgtgattgag atgataatta ccgaaaatct tactgaatgt
    38221 atcaatcagc cactagatga ttctgaagct caaaaggaac gcttagaaaa ggctatccga
    38281 tacttgatta aacggaaata aatgaatgtt ttgagacgat atgtgcaaag gtctattaac
    38341 tattagaata gtttaatggg agtcaaaaga agttgtaaaa aatctttaaa attaaaaaaa
    38401 cgcatagtat caggtattga aatgtactga ccccaaaaag ttagattttt tctgtctaac
    38461 ttttggggtg cagttcataa gaaccttggt aatatgcgtt ttattatggg gagatttata
    38521 cttttcgaaa atctcttcaa accaggtcag cttcaccttg ccgtagatat ggttactgac
    38581 ttcgtcagtt ctatccacaa cctcaaaaca gtgttttgag ctgacttcgt cagttccatc
    38641 cacaacctta aaacagtgtt ttgagctgac ttcgtcagtt ccatccacaa ccttaaaaca
    38701 gtgttttgag cagcctgcgg ctaacttcct agtttgcact ttaattttca ttgagtatta
    38761 cttcatcttc tcatgaaatt gagtttttgc ccagttcctc ttgattattc tacttgacca
    38821 ggccaagcat tcataccacc ttctacgttg gtaacggtga ggccttggga gatgagaaat
    38881 tggcaggtag atgcagagcg gactcctcct tgacaaataa catagtattc atggtcaggt
    38941 ttgagttctt tgtagccttg ctctaaggta cttaatggaa gatttttggc acctggtgca
    39001 tgtcctgctt ggaattcatg tgcttcacgg acatcgataa gttctagatt ttcattttgg
    39061 tattttccat aaaagtcagc catgctgata ctagtttcca tattctactc cttctgggtt
    39121 aaccattttg tatagtgaat aagcgccgtc aaggttttgg gcggtaaatc ctgcttgctt
    39181 gaggataggc tctgcgatat agctgcgcaa accactgtgg cagctgacga tgtaggcttg
    39241 ttttttgtcc agttcatcag cttcctcctt gacactttgt cagtttttga tacaatagta
    39301 caaaattaga ggaggtgggc tatgattcag aaacatgcga ttcctatttt agagtttgat
    39361 gacaatcctc aggcggttat catgcccaat cacgaggggc tggacttgca gttgccaaag
    39421 aagtgtgttt atgcattttt agatgaggag attgaccgct atgcaaggga agtaggggcg
    39481 gattgtgtcg gcgaattcgt ttctgctacc aagacctatc cagtctatgt catcaactac
    39541 aagggtgagg aggtctgtct ggctcaggct cctgttggct ccgctccagc agcccagttt
    39601 atggattggt tgattggcta tggtgtggag cagattatct ctactgggac ctgtggtgtt
    39661 ctagctgata tagaggaaaa tgcctttcta gtccctgttc gcgctctgcg agatgaagga
    39721 gccagttacc actatgtggc accttctcgt tatatggaaa tgcagccaga ggctattgct
    39781 gctattgagg aagttttgga agacagaggg attccttatg aagaagtcat gacctggacg
    39841 acagacggtt tttaccgaga aacggctgaa aaggtggctt atcgtaagga agaaggctgt
    39901 gctgttgtgg agatggagtg ttctgctctt gcggcagtag ctcaattgcg tggggttctc
    39961 tggggtgaat tgttgttcac agcagattct ctagcggact tggaccagta cgacagtcgt
    40021 gactggggct cggaagcttt taataaggcg ctagaactga gtttagcaag tgttcaccac
    40081 ctttagttgt actggcaaag gatttgtttt atcataaaat gtctagctca tacttttcaa
    40141 aaatatgttt aaacgaggtc accttcctct tgtcctaagc atgttgaggt tgggaaaaat
    40201 ctttaaaatc agaaaaacgt atcatatcag gtgatgaaaa ccttgatact atgcgtttta
    40261 tgttggtaag atttagagtg agatgaaatg atactcttcg aaaatctttt caaaccaggt
    40321 cagcttcacc ttgccgtagg tatatgttac tgacttcgtc agtcttatcc ggcaacctca
    40381 aaacggtgtt ttgagctgac ttcgtcagtt ctatttgcaa cctcaaaaca gtgttttgag
    40441 caatctgtga ctagctttct aatcgatgcc ttggttctca ttgcctataa tcaaaaagag
    40501 aaattttctc ctgaaaagca tatagagtag ctggcgttaa aagctcctgt cttgcttttt
    40561 tgacctatag tcacatctat caagtattgt tcttgcctaa gctatcaata aaaaggtggc
    40621 attttttagg cttggtgtta gtagattttg ccttatccta tctaagtcat ttcgaacttt
    40681 ttatggtaca atggaaacat gttattcaaa ttatctaagg aaaaaataga gctaggctta
    40741 tctcgtttat cgccagcccg tcgtattttt ttgagttttg ccttggtcat tttactaggc
    40801 tctcttcttt tgagcttgcc ctttgtccaa gttgaaagct cacgagcgac ttattttgat
    40861 catcttttca ctgctgtctc tgcagtctgt gtgacaggtc tctcaaccct tccagtagct
    40921 cacacctata atatatgggg ccaaataatc tgtttgctct tgattcagat cggtggtcta
    40981 gggctcatga cctttattgg ggttttctat atccagagca agcaaaagct tagtcttcgt
    41041 agccgtgcaa ctattcagga tagttttagt tatggagaaa ctcgatcttt gagaaagttt
    41101 gtctattcta tttttctcac gacctttttg gttgagagct tgggagctat tttgcttagt
    41161 tttcgcctta ttcctcaact tggctgggga cgtggtcttt ttagttccat ttttctagcg
    41221 atctcagcct tctgtaatgc cggttttgat aatttaggga gcaccagttt atttgctttt
    41281 cagaccgatt tactggtcaa tctggtgatt gcaggcttga ttattacagg cggccttggt
    41341 tttatggtct ggtttgattt ggctggtcat gtaggaagaa agaaaaaagg acgtctgcac
    41401 tttcatacga agcttgtact attgttgact ataggtttgt tgttatttgg aacggcaact
    41461 actctctttc ttgagtggaa caatgctgga acgattggca atctccctgt tgccgataag
    41521 gttttagtta gcttttttca aacagtgacg atgcgaacag ctggcttttc tacgatagat
    41581 tatactcagg ctcatcctgt gactcttttg atttatatct tacagatgtt tctaggtggg
    41641 gcacctggag gaacagctgg gggactcaag attacgacat tttttgtcct cttggtcttt
    41701 gcacgaagtg agcttctagg cttgcctcat gccaatgttg cgagacgaac gattgcgccg
    41761 cgaacggttc aaaaatcctt tagtgtcttt attatctttt tgatgagctt cttgatagga
    41821 ttgattctgc tagggataac agccaaaggc aatcctccct ttatccacct catatttgaa
    41881 accatttcag ctcttagtac agttggtgta acggcaaatc tgactcctga ccttgggaaa
    41941 ttggctctca gtgttatcat gccacttatg tttatgggac gaattggtcc cttgaccttg
    42001 tttgttagct tggcagatta ccatccagaa aagaaagata tgattcacta tatgaaagca
    42061 gatattagta ttggttaaga aaggaaagag catgtcagat cgtacgattg gaattttggg
    42121 cttgggaatt tttgggagca gtgtcctagc tgccctagcc aagcaggata tgaatattat
    42181 cgctattgat gaccacgcag agcgcatcaa tcagtttgag ccagttttgg cgcgtggagt
    42241 gattggtgac atcacagatg aagaattatt gagatcagca gggattgata cctgcgatac
    42301 cgttgtagtc gcgacaggtg aaaatctgga gtcgagtgtg cttgcggtta tgcactgtaa
    42361 gagtttgggg gtaccgactg ttattgctaa ggtcaaaagt cagaccgcta agaaagtgct
    42421 agaaaagatt ggagctgact cggttatctc gccagagtat gaaatggggc agtctctagc
    42481 acagaccatt cttttccata atagtgttga tgtctttcag ttggataaaa atgtgtctat
    42541 cgtggagatg aaaattcctc agtcttgggc aggtcaaagt ctgagtaaat tagacctccg
    42601 tggcaaatac aatctgaata ttttgggttt ccgagagcag gaaaattccc cattggatgt
    42661 tgaatttgga ccagatgacc tcttgaaagc agatacctat attttggcag tcatcaacaa
    42721 ccagtatttg gataccctag tagcattgaa ttcgtaaaga gggatgaccc ctcttttttg
    42781 atgcccaaga tggcaaatag agacagaagc cccttgtctt ctagtaaaag ttcttcaaag
    42841 gctggacttt atggtaaaat agaaggaagt gacaagagag agtaatactc aatgaaaatc
    42901 aaagatcaaa ctaggaaact agctgcgggc tgctcaaaac actgttttga ggttgtggat
    42961 agaactgacg aagtcagctc aaaacactgt tttgaggttg cagatagaac tgacgaagtc
    43021 agtaacatct atacggcaag gcgacgttga cgcggtttga agagattttc gaagagtata
    43081 agaaaaaatc agtcccctaa aggagcagat tatgaagtta ttgtctatcg ccatttctag
    43141 ctataatgca gcagcctatc ttcattactg tgtggagtcg ctagtgattg gtggtgagca
    43201 agttgggatt ttgattatca atgacgggtc tcaggatcag actcaggaaa tcgctgagtg
    43261 tttagctagc aagtatccta atatcgttag agccatctat caggaaaata aatgccatgg
    43321 cggtgcggtc aatcgtggct tggcagaggc ttctgggcgc tattttaaag tagttgacag
    43381 tgatgactgg gtggatcctc gtgcctactt gaaaattctt gaaaccttgc aggaacttga
    43441 gagcaagggt caagaggtgg atgcctttgt gaccaatttt gtctatgaaa aggaaggtca
    43501 gtctcgtaag aagagtatga gttacgagtc agtcttgcct gttcggcaga tttttgacta
    43561 ggaccaggtc ggaaatttct ccaaaggcca gtatatcatg atacactcgc tgatttatcg
    43621 gacagatttg ttgcgtgcta gccagttcta actgcctgaa catacttttt atgtcgatga
    43681 tctctttgtc tttacgcccc ttcagcaggt caagaccatg tactatctgc ctgtcgattt
    43741 ctatcgttat ttgattgggc gtgaggacca gtctgtcaat gagcaagtga tgattaagcg
    43801 cattgaccag caactcaagg tcaatcgact cttggtagac cagcttgatt tgtcccaagt
    43861 gagtcatcct aaaatgcgag aatatctgct gaatcatatt gaaatcacga cggtgatttc
    43921 cagtaccctg ctcaaccgat ctgaaacagc ggagcatctg gcaaaaaaac gccaattgtg
    43981 gacctatatt cagcagaaaa atccagaagt ctttcaggct attcgtaaga ccatgttgag
    44041 ccgtttgacc aaacattctg tcttgccaga tcgcaaactg tccaatgtcg tctatcaaat
    44101 caccaaatct gtttatggat ttaattaata taagtgtttt ataagaggga tttaagaaaa
    44161 attttaactt tttcttagtc ctttttaatt tcaggagatt atactagagt catcaaataa
    44221 agaaagactc taaggagaat cctatgaaat tcaatccaaa tcaaagatat actcgttggt
    44281 ctattcgccg tctcagtgtc ggtgttgcct cagttgttgt ggctagtggc ttctttgtcc
    44341 tagttggtca gccaagttct gtacgtgccg atgtggtcaa tccgacccca ggtcaagtct
    44401 tacctgaaga gacatcggga acgaaagagg gtgacttatc agaaaaacca ggagacaccg
    44461 ttctcactca agcgaaacct gagggcgtta ctggaaatac gaattcactt ccgacaccta
    44521 cagaaagaac tgaagtgagc gaggaaacaa actcttctag tctggataca ctttttgaaa
    44581 aagatgaaga agctcaaaaa aatccagagc taacagatgt cttaaaagaa actgtagata
    44641 cagctgatgt ggatgggaca caagcaagtc cagcagaaac tactcctgaa caagtaaaag
    44701 gtggagtgaa agaaaataca aaagacagca tcgatgttcc tgctgcttat cttgaaaaag
    44761 ctgaagggaa aggtcctttc actgccggtg taaaccaagt aattccttat gaactattcg
    44821 ctggtgatgg tatgttaact cgtctattac taaaagcttc ggataatgct ccttggtctg
    44881 acaatggtac tgctaaaaat cctgctttac ctcctcttga aggattaaca aaagggaaat
    44941 acttctatga agtagactta aatggcaata ctgttggtaa acaaggtcaa gctttaattg
    45001 atcaacttcg cgctaatggt actcaaactt ataaagctac tgttaaagtt tacggaaata
    45061 aagacggtaa agctgacttg actaatctag ttgctactaa aaatgtagac atcaacatca
    45121 atggattagt tgctaaagaa actgtcgaaa aagctgtta
//
LOCUS       DAVBEM010000011        43070 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVBEM010000011 DAVBEM010000000
VERSION     DAVBEM010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43070
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.011"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            1..780
                     /locus_tag="VQ548_000630"
                     /pseudo
     CDS             1..780
                     /locus_tag="VQ548_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(828..3371)
                     /locus_tag="VQ548_000631"
     CDS             complement(828..3371)
                     /locus_tag="VQ548_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HET2653531.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQKKVD
                     ILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTKTFT
                     EAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQAQT
                     GFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(3433..5055)
                     /locus_tag="VQ548_000632"
     CDS             complement(3433..5055)
                     /locus_tag="VQ548_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2653532.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            5261..6286
                     /gene="trpS"
                     /locus_tag="VQ548_000633"
     CDS             5261..6286
                     /gene="trpS"
                     /locus_tag="VQ548_000633"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HET2653533.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            6439..7917
                     /gene="guaB"
                     /locus_tag="VQ548_000634"
     CDS             6439..7917
                     /gene="guaB"
                     /locus_tag="VQ548_000634"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HET2653534.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(7968..9065)
                     /gene="recF"
                     /locus_tag="VQ548_000635"
     CDS             complement(7968..9065)
                     /gene="recF"
                     /locus_tag="VQ548_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HET2653535.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(9068..9436)
                     /gene="yaaA"
                     /locus_tag="VQ548_000636"
     CDS             complement(9068..9436)
                     /gene="yaaA"
                     /locus_tag="VQ548_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HET2653536.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKIDIPDMNIDILLTQSTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            9595..10845
                     /locus_tag="VQ548_000637"
     CDS             9595..10845
                     /locus_tag="VQ548_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET2653537.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSYLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHCPSKYGDEKHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSQLDLFSGFLRMYAGIDRENRNQARKMMNNQLLDL
                     KKGYFTELELEQTKEMIRRSLLLSQDNQSSLIERAYQNALLGKSSADFKSWIAKLEQV
                     DKDAICRAANNVKLQAIYFMEGIE"
     gene            10842..12125
                     /locus_tag="VQ548_000638"
     CDS             10842..12125
                     /locus_tag="VQ548_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET2653538.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTLVTEVDGDVKQYPAGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELITSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKLTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            12167..12988
                     /locus_tag="VQ548_000639"
     CDS             12167..12988
                     /locus_tag="VQ548_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2653539.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            12999..13544
                     /gene="pgsA"
                     /locus_tag="VQ548_000640"
     CDS             12999..13544
                     /gene="pgsA"
                     /locus_tag="VQ548_000640"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HET2653540.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            13541..14368
                     /locus_tag="VQ548_000641"
     CDS             13541..14368
                     /locus_tag="VQ548_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET2653541.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            14353..15192
                     /locus_tag="VQ548_000642"
     CDS             14353..15192
                     /locus_tag="VQ548_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET2653542.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPNQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            15185..15979
                     /locus_tag="VQ548_000643"
     CDS             15185..15979
                     /locus_tag="VQ548_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2653543.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            16038..16856
                     /gene="mreC"
                     /locus_tag="VQ548_000644"
     CDS             16038..16856
                     /gene="mreC"
                     /locus_tag="VQ548_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HET2653544.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKVSQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            16856..17350
                     /gene="mreD"
                     /locus_tag="VQ548_000645"
     CDS             16856..17350
                     /gene="mreD"
                     /locus_tag="VQ548_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HET2653545.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            17444..18622
                     /locus_tag="VQ548_000646"
     CDS             17444..18622
                     /locus_tag="VQ548_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET2653546.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            18846..19625
                     /gene="rpsB"
                     /locus_tag="VQ548_000647"
     CDS             18846..19625
                     /gene="rpsB"
                     /locus_tag="VQ548_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HET2653547.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            19704..20744
                     /locus_tag="VQ548_000648"
     CDS             19704..20744
                     /locus_tag="VQ548_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HET2653548.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            20991..21332
                     /gene="tnpB"
                     /locus_tag="VQ548_000649"
                     /pseudo
     CDS             20991..21332
                     /gene="tnpB"
                     /locus_tag="VQ548_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(21468..21755)
                     /locus_tag="VQ548_000650"
                     /pseudo
     CDS             complement(21468..21755)
                     /locus_tag="VQ548_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            21746..22144
                     /locus_tag="VQ548_000651"
     CDS             21746..22144
                     /locus_tag="VQ548_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2653549.1"
                     /translation="MKSPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPIIRKEISNWHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(22341..23261)
                     /gene="cysK"
                     /locus_tag="VQ548_000652"
     CDS             complement(22341..23261)
                     /gene="cysK"
                     /locus_tag="VQ548_000652"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HET2653550.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(23546..24181)
                     /locus_tag="VQ548_000653"
     CDS             complement(23546..24181)
                     /locus_tag="VQ548_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HET2653551.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVSVNLV"
     gene            24237..25535
                     /locus_tag="VQ548_000654"
     CDS             24237..25535
                     /locus_tag="VQ548_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2653552.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVIEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            25532..26194
                     /locus_tag="VQ548_000655"
     CDS             25532..26194
                     /locus_tag="VQ548_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HET2653553.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQACQFWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            26274..26822
                     /gene="raiA"
                     /locus_tag="VQ548_000656"
     CDS             26274..26822
                     /gene="raiA"
                     /locus_tag="VQ548_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HET2653554.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            26958..28931
                     /locus_tag="VQ548_000657"
     CDS             26958..28931
                     /locus_tag="VQ548_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HET2653555.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDALGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNTVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            28928..29380
                     /gene="rplI"
                     /locus_tag="VQ548_000658"
     CDS             28928..29380
                     /gene="rplI"
                     /locus_tag="VQ548_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HET2653556.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            29424..30776
                     /gene="dnaB"
                     /locus_tag="VQ548_000659"
     CDS             29424..30776
                     /gene="dnaB"
                     /locus_tag="VQ548_000659"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HET2653557.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            30778..31044
                     /locus_tag="VQ548_000660"
     CDS             30778..31044
                     /locus_tag="VQ548_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653558.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            31133..32479
                     /gene="cbpD"
                     /locus_tag="VQ548_000661"
     CDS             31133..32479
                     /gene="cbpD"
                     /locus_tag="VQ548_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HET2653559.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSGTVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      32562..32664
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            32735..33025
                     /locus_tag="VQ548_000662"
     CDS             32735..33025
                     /locus_tag="VQ548_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HET2653560.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            32988..33746
                     /locus_tag="VQ548_000663"
     CDS             32988..33746
                     /locus_tag="VQ548_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2653561.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            33784..34791
                     /locus_tag="VQ548_000664"
     CDS             33784..34791
                     /locus_tag="VQ548_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2653562.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            34791..35519
                     /locus_tag="VQ548_000665"
     CDS             34791..35519
                     /locus_tag="VQ548_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2653563.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            35638..36096
                     /locus_tag="VQ548_000666"
     CDS             35638..36096
                     /locus_tag="VQ548_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HET2653564.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            36098..38530
                     /locus_tag="VQ548_000667"
     CDS             36098..38530
                     /locus_tag="VQ548_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2653565.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFMELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALVLGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     ALRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKVKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            39172..39825
                     /gene="rr06"
                     /locus_tag="VQ548_000668"
     CDS             39172..39825
                     /gene="rr06"
                     /locus_tag="VQ548_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HET2653566.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            39822..41162
                     /gene="hk06"
                     /locus_tag="VQ548_000669"
     CDS             39822..41162
                     /gene="hk06"
                     /locus_tag="VQ548_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HET2653567.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILFLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            41245..41772
                     /locus_tag="VQ548_000670"
     CDS             41245..41772
                     /locus_tag="VQ548_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HET2653568.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            41851..>43070
                     /locus_tag="VQ548_000671"
     CDS             41851..>43070
                     /locus_tag="VQ548_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HET2653569.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEGVRSGD
                     TPKVTSSGDEVESHLKKILSEIQTQLDRKRHAKTVALINKLQDIKRTYSYKLNVLEEK
                     PKAELTSKTKEELTAAFEQFKKDTLPTEPGKKVAEAEKKVAEAEKKAEDQKEEDRRNY
                     PTNTYKTLELEIAEFDVKVKEAELELLKEKAKKPLNEGTIKQAKEKVESKKAEATRLE
                     NIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPKPEKPAPAPKPENP
                     APKPEKPAPAPKPENPAEQPKAEKPADQQAEEDYARRSEEEYNRLTQQQPPKTEKPAQ
                     PSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWYYL
                     NANGSMATGWLQNNG"
BASE COUNT        13639 a         7059 c         9270 g        13102 t
ORIGIN      
        1 gacctactac tatcacttga aacagctaga taaaacagat aaggaccaag agcttaaagc
       61 tgaaattcaa tccatcttta tcgaacacaa gggaaattat ggttatcgtc ggatttattt
      121 agaactaaga aatcgtggtt atctggtaaa tcataaaaga gttcaacact tgatgaagta
      181 ctcaatttac aagctaaaat gcgacagaaa cgaaaatatt cttctcataa aggagacgtt
      241 ggcaagaagg cagagaatct cattcaaggc caatttgaag gctctaaaac aatggaacag
      301 tgctacacag atgtgacaga atttgccatt ccagcaagta ctcaaaagct ttacttatca
      361 ccagttttag atggctttaa tagcgaaatt atcgcctata atctttcaac ttcacccaac
      421 ttagaacaag tacaaacaat gttggaacag gcattcacag agaagcacta cgagaatacg
      481 attctccata gtgaccaagg ctggcaatat caacacgatt cttatcatca gtttcttgag
      541 ggtaagggaa ttcaagcatc tatgtcacgc aagggaaaca gccaagacaa cggtatgatg
      601 gaatctttct ttgggattct gaaatcggaa atgttttacg gttatgagaa gagctttaga
      661 tctttagaaa accttgaaca agctattgtg gactacattg attactacaa caacaaacga
      721 attaaggtaa aactaaaaga acttagccct gtgcaataca gaactaaatc cttcggataa
      781 attaattgtc taactttttg gggtcagtac attaactggt cgatttttta tgccttagat
      841 gactttcgtc tgtgattata gattccaaat agtaagagag aagtaaagga acagattgct
      901 ccagtaataa aaccattggg aatgaaggaa agtgtaatag ttcctttccc cttgggaatg
      961 tcaactttca taaatccagt ttgagcttgt ttaatttcta ttttcttacc atcttggtag
     1021 gcagaccaac ctttgtcata aggaatggtg aagaaaatag atgtatcttg ttggacatca
     1081 tatgtagcaa aaaccttgtt tttagaagtt gatactgtga caggttgttc tttaattttt
     1141 tgaattgcct cggtgaaagt tttggtatct aaacgataga aggtaggaga ttcaaatgat
     1201 acttgtgaat ttccagggaa actaacattg atattgaaag tttttttctc tttagtatat
     1261 cctagattaa agaaggagaa gacattatca gttgtaaaag tctttttttc accatttaca
     1321 aggatgtcaa ccttcttttg tttatcgtta gaaaagtgaa ggtttatgaa agagagataa
     1381 acttggctgt tttctggaac ttcaatttga tactggattg ctgcatcttc atttgaagaa
     1441 cttgtgacac taatcaaatc attagtattt tctgtttttt cataaggtat tggagaaaaa
     1501 taatcaaaat tgacgttagc aagttgattt aaaaatgagg cctgattatc caaggtatgt
     1561 tcattgaact tgacatcatt gtaaacagat tgactagcaa ctgcaatcgg aagagagtat
     1621 tgattttcat atagggtaag attatctttt tgatagatat ctttaaagcc atacttatca
     1681 ataggactgt ctgagatatt gtactggata ccaaataaac tatcagccaa aatactatta
     1741 tttgcatatc ggagattgag attagtccca gaggatttaa aaccaagttt atctaaagta
     1801 gagcttgatg aacgatttcg aacagatgaa aattgagaga ttccattgta gttgaatttc
     1861 atactgtcat ttcctgtctg agtttgtagt ttttcagtac gagtaaattg atttccaata
     1921 tatgttgaga aagattccat agctgggata tctcgactat aagcacttcg agaagcaaat
     1981 ccccattcct tagcaattcc gtccatttga gatgaagcat ttaaactcat ttcaaccagt
     2041 ataaataaag agattagaat ggcaaataga ttcacagata taaacttttt gataactgca
     2101 aggagtaaaa gagaatagac aaccaaaaat tcaagagtaa gcagaatatt caaatctgtt
     2161 aaaaaagaat aatgcgattt tagatagatg gtagctaaaa atcctgctac tacaagaaaa
     2221 agcgaaacta aaaaattcca gactttaagt tctttcagac gctttaagac ttctgctgct
     2281 gtgtaaatta acaaggtaga gaaaatccaa gcatagcgat gtaaaaacat gtttggagta
     2341 tgcatgcctt gccaaaataa gtcaagagct tctatgtaaa agcttgcaat tagaaatgca
     2401 aagaatatta catatatgag tttcacgtga aacttaatag atttcagcgt aaaaaataaa
     2461 atggtcaaaa taaagggaaa tagtccaaca aaaatcattg ggatggcccc atactttgtt
     2521 gtgtcaaagg aaccaatgaa ttgcttagca aagagatcaa gataccagct actttcagtt
     2581 tgaaactttg taacttcagt caatttttcc ccatgtgtct gtaaatcaaa tagagtggga
     2641 agagtcataa tcaaactagc cataccagct aaaaaggaga taactatgaa atcaagaaca
     2701 gatgattttc gagtcttaaa gtcccacgaa atttgacaga gataccagaa aataagaaac
     2761 aatactgtca tatatccaaa ataataattt tgaataaata agattgacag acttgtaaag
     2821 tacaatagga gtttcttttc agttatcagt agatgtaaac cagttataat taaaggaatc
     2881 aagataaaaa catctagcca ggtttttatc tctaattgac tgacagtgaa actcatcaga
     2941 gcataggaag tagataaggc tagttttaaa gtctgaggga tagattgaaa caatttattc
     3001 aaactaaaaa aggttgacag accaatcaat ccaaatttta agagagtggt cagatagaca
     3061 gcatctggca tattcgttag atcaaaaaag taaactagag gcgcgagaaa actacccaag
     3121 taataactag atagggcata gaagtttagc cctagaccac ttgtaaaggt gtaaaacaga
     3181 ctactatttc catgtaggat atttcgtaag gctacatcaa aaataacgta ttgatgaaag
     3241 ccatctccta atagaggaga gttgtcgcta ttccagtaga taccttgaga tagatatact
     3301 ccagacataa tcactacagg aatgatgaaa gaaataaaat aggttcgata tgtttttaaa
     3361 aatgatttca tgttacctcg tagaatgata gaaaactcag ttggttaacc caactgagtt
     3421 ttgaagtttt atttagtctt tccaaagttc tttaactttt gcttgtactt ctgcattttc
     3481 taggaattca tcgtaggttt catcgatacg gtcaatgacg ccatttttag ataagacaat
     3541 gatatggtta gccaaagttt gaataaactc gtggtcatgg ctggcaaaga tgattgattc
     3601 tttaaagttt ttcagtccat cattcaagct tgagatagat tccaagtcca agtgatttgt
     3661 tggatcatca agtacaagga catttgattt taagagcatg agttttgaaa gcatgacacg
     3721 aactttttct ccccctgaca agacatttac aggtttgtta acttcatctc cagagaagag
     3781 catacggccg aggaaaccac gtaggaaagt attgtcatct tcttctttac ttgcgaattg
     3841 acgcaaccag tcaagaattg attctcctcc tgcaaaatca gctgagttat cttttggtag
     3901 gtaagattga ctagttgtaa ctccccactt gacagttcct tcatagtcaa tatctcccat
     3961 gattgcacga attaatgcag tcgtttgaat atcattttgt ccaataagtg ctgtcttatc
     4021 atctggacgc aagatgaaac taatattatc caagatagtt tcaccatcaa tctttacagt
     4081 tagattttct actgtcaaga gatcattacc aatctcacgt tccgctttaa agttgataaa
     4141 tggatattta cgactagatg gtacaatctc ttctagctca atcttatcaa gcattttctt
     4201 acgtgatgtt gcctgccttg acttagaagc attggcagag aaacgagcaa cgaattcttg
     4261 caattgttta attttttctt ctgctttagc attacggtct gctagcaatt tagcagcaag
     4321 ctcagaagat tccttccaga agtcgtagtt tccgacatag agtttgattt ttccaaagtc
     4381 aaggtcggcc atgtgagtac aaactttgtt taagaagtga cggtcgtggg atactacgat
     4441 aactgtgtta tcaaagtcaa tcaagaagtc ttctaaccaa gtaatcgatt ggatatccaa
     4501 accgttagta ggctcgtcca agagaagaac atctggttta ccaaaaagtg ctttggcgag
     4561 gagaaccttt actttttcac cgttggccaa ttcgctcatg ttttggtagt gtaattcttc
     4621 tggaatgttt aggttttgaa gtagttgaga ggcttcactc tctgcttccc aacctccaag
     4681 ttcggcaaac tctccttcga gttcggcagc acgaaccccg tcctcgtctg agaaatcttc
     4741 cttcatgtag atagcatctt tctctttcat gatgctataa agtttttcat ttcccatgat
     4801 aacgacatca atggcacgtt catcttcgta gtcaaagtga ttttgacgaa gaacagagag
     4861 acgttcatct ggaccaagag agatgtgacc agtagtaggt tcgatatctc cagctaaaat
     4921 ttttaaaaag gttgattttc cggcaccatt agcaccgatt aatccgtaag tatttccttc
     4981 tgtaaatttg atattgacat catcaaaaag tttgcgatca ctaaaacgta gtgaaacatc
     5041 agatactgta agcaatgttt ttctcctata tgtgtaatat atttattcta ctagaaaata
     5101 cagaaatatt caaattttta tttgtcaatt ttgtgtaaat tatatttaca gtatccttta
     5161 cacaaatctg taaaaagcaa ggctgattta ttttgataaa ttacggttat ttcattaaaa
     5221 aaatgctata attgaaagga ctatatcgaa ggagaacaaa atgactaaac ccattatttt
     5281 aacaggagac cgtccaacag gaaaattgca tattggacat tatgttggaa gtctcaaaaa
     5341 tcgagtatta ttacaggaag aggataagta tgatatgttt gtgttcttgg ctgaccaaca
     5401 agccttgaca gatcatgcca aagatcctca aaccattgta gagtctatcg gaaatgtggc
     5461 tttggattat cttgcagttg gattggatcc aaataagtca actattttta ttcaaagcca
     5521 gattccagag ttggctgagt tgtctatgta ttatatgaat ctagtttcgt tagcacgttt
     5581 ggagcgaaat ccaacagtca agacagagat ttctcagaaa ggatttggag aaagcattcc
     5641 gacaggattc ttggtctatc caatcgctca agcagctgat atcacagctt tcaaggctaa
     5701 ttatgttcct gttgggacag atcagaaacc aatgattgag caaactcgtg aaattgttcg
     5761 ttcttttaac aatgcatata actgtgatgt cttggtagag ccggaaggta tttatccaga
     5821 aaatgagaga gcagggcgtt tgcctggttt agatggaaat gctaaaatgt ctaaatcact
     5881 aaataatggt atttatttag ctgatgatgc ggatactttg cgtaaaaaag taatgagtat
     5941 gtatacagat ccagatcata tccgcgttga ggatccaggt aagattgagg gaaatatggt
     6001 tttccattat ctagatgttt ttggtcgtcc agaagatgct caagaaattg ctgatatgaa
     6061 agaacgttat caacgaggtg gtcttggtga tgtgaagacc aagcgttatc tacttgaaat
     6121 attagaacgt gaactgggtc ctattcgtga gcgccgtatt gaatttgcta aggatatggg
     6181 agaagtttat aatatgattc aaaaaggtag tgaaagagcg cgtgaagttg cgggtcaaac
     6241 cctatctgag gtaaaagggg caatgggact tcattacttt aactaagttt attttacaag
     6301 aaactatcat ttctatctcg aagaaaagat agttttttta tttacccctg taacatttga
     6361 caaattttta tagaatggta tgatagatac aatataaaaa gagtcaagct caaaaagaaa
     6421 gaaaagagga aacttcgaat gtctaattgg gacactaaat ttttgaaaaa aggttttacc
     6481 tttgatgatg tattgcttat tccagctgaa agtcatgtgt tgcctaacga tgcagattta
     6541 acaactaaat tggcagataa tttgacttta aatatcccaa ttattaccgc tgccatggac
     6601 acagttacag agagtcaaat ggccattgct attgctcgtg caggcggtct cggagttatc
     6661 cataaaaaca tgtcaattgc tcaacaagca gacgaggttc gtaaggtaaa acgttctgaa
     6721 aatggagtta ttattgatcc gttcttcttg acgcctgaac atacaattgc tgaagcagat
     6781 gagcttatgg gtcgttaccg catcagtggt gttccagttg ttgaaacact tgaaaatcgt
     6841 aaattggttg gtattttgac aaaccgagat cttcgtttta tttcagatta taatcaacca
     6901 atttcaaacc atatgactag tgaaaatctt gttactgctc ctgtgggtac ggatcttgca
     6961 acggctgaga gtattcttca agagcatcgt attgaaaaac ttccgttggt cgatgaagaa
     7021 ggcagtcttt ctggtttgat cactatcaaa gatattgaaa aagttattga gtttccaaat
     7081 gcggctaaag atgagtttgg tcgtcttcta gttgcaggtg cagtaggtgt tacttcagat
     7141 acatttgaac gtgcagaggc tctttttgag gcaggagcgg atgcgattgt tattgatact
     7201 gcacatggtc attctgcagg tgtcttgcgt aaaattgccg agattcgtgc tcatttccca
     7261 gatcggactt tgattgctgg aaatattgct actgctgaag gtgcacgtgc cctttatgaa
     7321 gcgggtgtag acgttgttaa ggttggtatt ggaccaggtt ctatctgtac tactcgtgtg
     7381 attgctggtg ttggtgttcc gcaagtaaca gctatctacg atgctgcagc tgttgcgcgc
     7441 gaatatggta aaacgattat tgctgacggt gggatcaagt attctggaga tattgtaaaa
     7501 gcacttgctg caggtggaaa tgctgttatg cttggatcta tgtttgctgg aactgatgaa
     7561 gctccaggcg aaactgaaat cttccaagga cgtaaattca agacttaccg tggtatggga
     7621 tcaattgctg ctatgaagaa aggttcaagc gaccgttatt tccaaggttc tgtcaatgaa
     7681 gcaaacaagc ttgttccaga aggaattgaa ggtcgtgttg cttataaagg agcggcagct
     7741 gatattgttt tccaaatgat tggtggtatt cgctctggta tgggttactg tggtgcagct
     7801 aaccttaaag aactacacga taatgctcaa tttattgaaa tgtctggtgc tggtttgaaa
     7861 gaaagccatc ctcatgatgt gcaaattact aatgaggcac caaattattc tatgtaaaaa
     7921 acaatgaaaa gaactccagt gaaaacagga gttcttttac aatgttgtca atttccattt
     7981 acagcagctt taccatcctg aatagtgaag atacttagat tttctggcag attttgaaga
     8041 tggtctaagc ttgttgttgt gataaaggtt tggattgatt gagaaatcgt ttctaataat
     8101 tttaactgtc tagtgttgtc aagttcactc atcacatcgt caagcagtaa tataggagat
     8161 tctgtggtaa tgctttccat taattcgatt tctgctaatt ttatcgagag gacgagacta
     8221 cgatgttgac cttggcttcc gaaactagca tccatcccat ttatataaaa agaaatgtca
     8281 tctcgatgag gaccgacacc agtattcttt ttaaataaat ctctggatct acttttttct
     8341 aaagcaattt tgaaagattc ggataagttt tgtttgtcag ttatattgac agaagattga
     8401 taggatattg acaactcttc gatctgatta gagagttcaa aatgtttctt acgcccaaat
     8461 gattctagtt tttttatgaa atctaagcgg tgattcatta cacgacatcc ataatcaact
     8521 agctgatcat ctaacacaga aaggaatgtt tcatctattt tttgagctga ttttaggtaa
     8581 gtgtttcttt gctttaggat gtggttataa ttggttaagt cagataaata gattggctta
     8641 atttgcccaa gttccatatc aatgaatttt cgtcgaatcg aaggtgctcc tttaattagt
     8701 tgtaaatctt caggagcaaa taagacaaca ttcatgtgtc ctacataatc tgaaaggcgt
     8761 gcctgtttta agtgattaac ttttgttaca cggccttttt gtgttagttc gatttctagg
     8821 ggaatggatc cagttttttt ctgaacgaga cctgaaagat gaagttgttc ctcatcaaaa
     8881 tgaatgagat ttttatctgt tcgagttcga tgactacgcg ttaaggctaa aaaatagata
     8941 gcctctaaca tgtttgtttt tccttgtgca ttacgtccca aaaagacatt caatttagga
     9001 ttaaagtcta ttttcgtttc tttgtaatta cgaaaagtct tgagagatag atgttgtagc
     9061 cacatgatta tctaccaggg aatcgtggag cttgttggct tttaggtgat gaagcaggtt
     9121 tcgatttgtc ttttttaact cccttattca tctttttgac aagtttagcg atccgttctt
     9181 tttcaacttt atcagcttgg tattcatctt gttcttcaga agtagattgt gtcaacaaga
     9241 tgtcaatgtt catgtcaggg atgtcaattt tatcgccaat acgaagtttt ttaccacgac
     9301 gactctctaa ttccctatta aagtaaacag aatgttcaga gagaaatgat ttaatagctc
     9361 ctccgctatg tgtaattcca agttctttga gtagtgcttg gagggtaata aattcttcaa
     9421 ataatttgta ttccataatt cacctcaatc tttggtatta taccatattt tcctaaaaat
     9481 agtgagagat acagcgagaa atgtaagcga tttttatttc aaaagtgtta cagggaacaa
     9541 gaaaatttca ggttttcgtg atataataga agtctgtata taaggagata aatcatggag
     9601 ttagtgcatg gaatttcaac acattttatc caatcaaaaa agtttaaaac aaacaaaatt
     9661 accgtgcgtt ttaccgctcc attatccctt gatacgattg caggtcacat gttgagtgca
     9721 agtatgctag agactgctaa tcagatgtac cccacttctc aagatttgag gagacacttg
     9781 gccagtctat acggtacaga tatgtcaacc aattgtttca gaagagggca aagccacatt
     9841 atagaattga catttaccta tgttcgtgat gagtttttaa gtaggaaaaa cgtgctaact
     9901 tctcagattt tggaacttgt aaaagaaact cttttttcac ccgtagtagt tgataatggg
     9961 tttgatccgg ccttatttga aattgagaaa aaacaattgc tagcaagttt agcagctgat
    10021 atggatgatt ctttttattt tgcacataaa gaattggata aattgttttt tcatgatgaa
    10081 cgtcttcaat tggaatatag ttatttacga aatcgtattt tagctgaaac tccacaaagt
    10141 tcttattctt gtttccaaga atttttagcc aatgatcgaa tagatttctt tttcctaggt
    10201 gattttaatg aggttgaaat tcaaaatgta ttagaatcat ttggctttaa aggtcgaaaa
    10261 ggagatgtga aggttcagta ttgtcaacct tattctaata tccttcagga aggtatggtt
    10321 cggaaaaatg tgggacaatc cattttggaa ttaggttatc attgcccttc taaatatggt
    10381 gatgagaaac atttacccat gattgtaatg aatggtttac ttggtggatt tgctcactct
    10441 aaacttttta caaatgtccg tgaaaatgct ggattagctt atactatttc aagtcagctc
    10501 gatttattta gtggattctt gaggatgtat gctggtattg accgagaaaa tcgtaaccag
    10561 gctcgtaaaa tgatgaataa tcaactgctt gatttaaaaa aaggttattt tacagagctt
    10621 gagttagagc agaccaagga aatgattcgt cggtctttgt tactttctca agataaccaa
    10681 tcttcattga ttgaacgtgc ttatcaaaat gccttacttg gaaaatcttc agcagatttt
    10741 aaaagttgga ttgcaaaact cgagcaagtt gacaaagatg ctatttgtag agcagctaac
    10801 aatgtgaaac tacaagcgat ttactttatg gaaggaatag aatgacaaag gttgtttttg
    10861 aagaaaaata ctatccagct gtaaaagaaa tggtttatcg aactcgtttg gcaaatggat
    10921 tgacagtagc tcttttgcct aaaaaggaat ttaaagaggt ttacgggagt gtaactgtac
    10981 agtttggttc ggtagatacg cttgtcacag aagttgatgg agatgtaaaa caatatcctg
    11041 caggaattgc tcattttctt gaacataaat tatttgaaag agaagattct agcgatttga
    11101 tgtcggcttt tacgagtcta ggtgcagata gtaatgcctt tacaagcttt acaaaaacaa
    11161 actatctttt ttcagcaacg gattattttt tagaaaattt agatttactt gatgaattga
    11221 taacatcagc acactttact gaagcttcca ttctgacaga gcaggatatt attcagcaag
    11281 aacgagaaat gtaccaagat gatccagatt cgtgtttatt cttttcaact ttagcgaatt
    11341 tgtatcctgg tacaccttta gcaactgata tagttggaag tgaggagtcc atttcccaaa
    11401 tcaatctaac taatttgcaa gaaaatttta caaagtttta caaacctgta aacatgtctc
    11461 tgtttttagt tggtaatttt gatgtggagc gagtacagga ctattttgaa agcaaagaac
    11521 tgaaagattc agattttcag gaagtagcaa gagaaaagtt gtttttacag cctgtaaagc
    11581 taacagatag tatgagaatg gaagtatctt ctcccaaact agcgattgga gttagaggta
    11641 agcgagaagt ttctgaagcg gattgctatc gacatcatat tttattaaaa ttattgtttg
    11701 caatgatgtt tggttggact tcggatcgtt ttcaaaaatg ttatgaatca ggtaaaattg
    11761 atgcgtcctt atctctggaa gttgaaataa caagtcgctt tcattttgtc atgttgacaa
    11821 tggatacgaa agagccagtt gctttgtctc atcaatttag gaaggctatt cgtaatttta
    11881 caaaggattt agatattaca gaggaacatt tagatattat caaaagagag atgtttggcg
    11941 aatttttcag tagcatgaac tctcttgaat ttattgcaac gcaatatgat gcttttgaaa
    12001 atggtgagac aatttttgat ttgccgaaaa ttttacagga aattacttta gaggatgtcc
    12061 ttgatgctgg acatcattta atagatgatg gtgacatagt tgattttaca atatttccat
    12121 cgtagtaacc tatcataata gacactagaa agaagggatg acaagtatga gaaaaaaaac
    12181 aattggagag gttttacgat tagctagaat caatcaggga ttgagtttag atgaattgca
    12241 gaaaaagaca gaaatccagt tagatatgtt ggaagcaatg gaagcagacg atttcgatca
    12301 acttccaagt cctttttaca cgcgttcttt cttgaaaaaa tatgcatggg ctgttgagtt
    12361 agatgaccaa attgttttgg atgcttatga ttctgggagt atgattactt atgaggaagt
    12421 agatgttgat gaagatgagt tgacaggtcg tagacgttca agtaagaaaa agaagaaaaa
    12481 aacatcattt ttacctttat tttattttat cctttttgct ttatcgattt taatttttgt
    12541 gacttattat gtttggaact atattcaaac tcaaccagag gagccttctc tttctaatta
    12601 cagtgtggtt caatcaacaa gttcaactag ctctgttccc cactcctcaa gtagtagttc
    12661 ttctagtata gaatcagcta taagtgtatc aggcgaagga aatcatgtag aaatcgctta
    12721 taagacaagt aaggaaacag ttaaattgca attggcagtt tcagatgtta caagttgggt
    12781 cagtgtttca gaaagcgaac ttgagggcgg tgtaacctta tcgccaaaga agaaaagtgc
    12841 agaagcaaca gttgcaacta aaagtcctgt aacaattacg ttaggtgttg taaaaggtgt
    12901 tgatttgaca gtagataatc agactgttga tttatcgaaa ttaacagctc agactggaca
    12961 aatcactgta acctttacta aaaattaagg aaaaacgaat gaaaaaagaa caaattccca
    13021 atctcttaac aataggtcga attctcttta tacctatttt tatctttatt ttaacgatag
    13081 gaaattcgat agagagtcat atagttgcag ctattatctt tgctgttgcc agtattaccg
    13141 actatttaga tggatattta gctcgtaaat ggaatgtggt cagtaatttt ggtaaatttg
    13201 cagatcctat ggcggataag ttactagtta tgtcggcttt tattatgttg attgagttag
    13261 gtatggctcc ggcttggatt gttgcagtga ttatatgtcg tgagttagct gtgacaggtt
    13321 taaggctttt attggttgaa actggtggaa caattttagc agcagcaatg cctggaaaaa
    13381 ttaaaacttt tagtcagatg tttgctatta ttttcttgct attacattgg actttgcttg
    13441 gtcaagttct actttatgta gccttatttt tcactatcta ctctggctat gactatttta
    13501 agggtagtgc ctatgtattt aaagggacat ttggttcgaa atgaaatcaa taattgatgt
    13561 aaaaaatctt tcttttcgct ataaagaaaa tcagaactac tacgatgtga aggatattac
    13621 gtttcacgtg aaacgtggag aatggctttc gattgtaggg cataatggta gtggtaaatc
    13681 aacgacggtt cgattaattg atggcttact ggaagcagaa tccggagaga ttgtaattga
    13741 tggccaacgt ttgactgagg aaaatgtttg gaatatacgt cgtcaaatcg gtatggtttt
    13801 tcaaaatcca gacaatcaat ttgttggagc gactgttgaa gatgatgttg cttttggttt
    13861 ggaaaatcag ggactttctc gtcaagaaat gaaaaagaga gtggaagaag ctctggcttt
    13921 agttggcatg ttggacttta aaaagagaga gccagcgcgt ctatcaggtg gtcaaaagca
    13981 acgtgtggcc attgcaggtg ttgtagccct aagaccagct attttaatct tagatgaagc
    14041 aacgagtatg ttggatcctg aggggcgtag agaacttatt gggacagtaa aaggaattcg
    14101 aaaagactat gatatgacgg tcatttctat tacccatgat ttggaagaag tcgccatgag
    14161 tgatcgcgta ttggtcatga aaaaagggga aattgaatca actagtagtc caagggagct
    14221 tttctctcga aatgatttag atcaaattgg attagacgat ccttttgcta atcaattaaa
    14281 aaaatctttg agccagaatg gctatgattt acctgaaaat tatttgacag aaagtgagct
    14341 agaggataag ctatgggaat tgctctagaa aatgtgaatt ttacatatca agaaggtact
    14401 cccttagctt cagcagcttt gtcggatgtt tctttgacga ttgaagatgg ctcttataca
    14461 gctttaattg ggcacacagg tagtggtaaa tcaactattt tacaactctt aaatggttta
    14521 ttggtgccaa atcaagggag tgtgagggtt tttgatacct taatcacctc gacttctaaa
    14581 aataaagata ttcgtcaaat tagaaaacag gttggcttgg tatttcagtt tgctgaaaat
    14641 cagatttttg aagaaacggt tttgaaggac gttgcttttg gaccgcaaaa ttttggagtt
    14701 tctgaagaag atgctgtgaa gactgcgcgt gagaaactgg ctctggttgg aattgatgaa
    14761 tcactttttg atcgtagtcc gtttgagctg tcagggggac aaatgagacg tgttgccatt
    14821 gcaggcatac ttgccatgga gccagctata ttagtcttag atgagccaac agctggtcta
    14881 gatcctctag ggagaaaaga gttgatgacc ctgttcaaaa aactccacca gtcagggatg
    14941 accatcgtct tggtaacgca tttgatggat gatgttgctg aatatgcgaa tcaagtctat
    15001 gtaatggaaa agggacgttt agtaaagggg ggcaaaccaa gtgatgtctt tcaagacgtt
    15061 gtttttatgg aagaagttca gttgggagta cctaaaatta cggccttttg taaacgattg
    15121 gctgatagag gcgtgtcatt taaacgatta ccgattaaga tagaggagtt caaggagtcg
    15181 ctaaatggat agtatgattt tagggcgtta tatcccaggg gattcgattg ttcaccgatt
    15241 ggatccacgt agcaaattgc ttgctatgat gctactgatt ttgattgtgt tttgggctaa
    15301 taaccccttg acgaatctga ttctttttat agcgacaggg atatttattg ccttgtcagg
    15361 agtatctctt tcatttttta ttcagggctt gaagtctatg tttttcttga ttgccttcac
    15421 aactattttt caactatttt tcatttctaa tgggaatgtt ttatttgagt tttcgtttgt
    15481 gagaatcacg gattatgctt tgcaacaagc tgggattatt ttttgtcgct ttgtattgat
    15541 tattttcttt tcaactttgt taaccttaac aaccatgcct ttaagtttgg catcagctgt
    15601 cgaagcttta ttagcacctt taaagcgtgt gaaagttcca gttcatgaaa ttggattgat
    15661 gctgtctatg agtttgcgtt ttgtcccaac cttgatggat gatacgactc ggattatgaa
    15721 tgcacagaaa gctcgtggag tggattttgg agaaggaagc atcgttcaaa aagtaaaggc
    15781 gatgattccc attttgattc ctctttttgc gacaagttta aaacgtgcag attccttggc
    15841 tatcgctatg gaagcgcgtg gctatcaggg tggaaaaggc agaagtcaat accgacaatt
    15901 gaaatggact ctaaaggata cgctgaccat tcttgttatt ctcgtacttg gttgttgttt
    15961 atttttctta aaatcttagt agctttcagg aattgataaa aagttactgt aacagttttt
    16021 gatataaagg taggaatatg aaccgtttta aaaaatcaaa atatgtcatt attgtttttg
    16081 tcactgttct gcttgtgtca gctctcttag cgacgactta ttcaagtaca attgtgacaa
    16141 aattaggaga tggaatctca ttggttgata gagttgtaca aaaacctttt cagtggtttg
    16201 attctgtcaa atcagatttg gctcatttga cacgaacata taatgaaaat gaaagtttga
    16261 agaaacagct ttaccaatta gaagttaaat caaatgaggt ggaaagttta aagacagaaa
    16321 atgaacaact gcgccaattg cttgatatga agtctaaatt gcaagccaca aagactttag
    16381 cagcagatgt tattatgcgt tctccggtat cttggaagca ggagttgacc ttagatgcag
    16441 gtagatcaaa aggtgcttct gagaacatgt tagctattgc aaatggtggc ttgattggga
    16501 gtgtttcaaa agtagaggag aactctacta tagtcaacct tctgacaaat acggaaaatg
    16561 ctgataagat ttctgttaaa attcaacatg gctctactac aatttatgga attattattg
    16621 gctatgacaa ggaaaatgac gttcttaaag ttagccaatt aaatagtaat agcgatatta
    16681 gtgcgggaga taaggtgact actggtggat taggaaactt taacgttgct gatattcctg
    16741 ttggtgaagt ggttgccaca acgcatagta cagactattt gacacgagaa gtaactgtta
    16801 aattgagtgc agatactcat aatgtagatg tgatagaatt agtggggaat tcataatgag
    16861 acagttgaag cgagttggag tatttttatt gcttcctttc tttgttctaa ttgacgccca
    16921 tattagccag cttctgggct catttttccc ccatgtacat ttggctagtc attttctttt
    16981 tctatttctc ttatttgaga cgatagaagt atcagagtat ctctacctag tctattgttt
    17041 tgttataggc ttggtttatg atgtttactt tttccatcta atagggatta caactctctt
    17101 atttatctta ttgggagcct tccttcataa attgaatagt gttattttgt tgaatcgttg
    17161 gacaagaatg ctagctatga ttgtactgac attcctgttt gaaatgggta gttatctttt
    17221 ggcttttatg gtagggttga cagtagatag catgtcgatt tttatagtct atagcttggt
    17281 accgacgatg attttaaatt ttttatggat tactgttttt caatttattt ttgaaaaata
    17341 ttatctataa gaacgacata taaatgtaac aaaggcgtaa tatttattag gccttttttt
    17401 ggtatactag tattgtcttt aaaagaagga gtatctacgt aatatgaaga aaaaaatctt
    17461 agcgtcactt ttattaagta cagtaatggt ttctcaagta gctgttttaa caactgcgca
    17521 tgcagaaacg actgatgaca aaattgctgc tcaagataat aaaattagta acttaacagc
    17581 acaacaacaa gaagcccaaa aacaagttga ccaaattcag gagcaagtat cagctattca
    17641 agctgagcag tctaacttgc aagctgaaaa tgatagatta caagcagaat ctaagaaact
    17701 cgagggtgag attacagaac tttctaaaaa cattgtttct cgtaaccaat cgttggaaaa
    17761 acaagctcgt agtgctcaaa caaatggagc cgtaactagc tatatcaata ccattgtaaa
    17821 ctcaaaatca attacagaag ctatttcacg tgttgctgca atgagtgaaa tcgtatctgc
    17881 aaacaacaaa atgttagaac aacaaaaggc agataaaaaa gctatttctg aaaaacaagt
    17941 agcaaataat gatgctatca atactgtaat tgctaatcaa caaaaattgg ctgatgatgc
    18001 tcaagcattg actacgaaac aggcagaact aaaagctgct gaattaagtc ttgctgctga
    18061 gaaagcgaca gctgaagggg aaaaagcaag tctattagag caaaaagcag cagctgaggc
    18121 agaggctcgt gcagctgcgg tggcagaagc agcttataaa gaaaaacgag ctagccaaca
    18181 acaatcagta cttgcttcag caaacactaa cttaacagct caagtgcaag cagtatctga
    18241 atctgcagca gcacctgtcc gtgcaaaagt tcgtccaaca tacagtacaa acgcttcaag
    18301 ttatccaatt ggagaatgta catggggagt aaaaacattg gcaccttggg ctggagacta
    18361 ctggggtaat ggagcacagt gggctacaag tgcagcagca gcaggtttcc gtacaggttc
    18421 aacacctcaa gttggagcaa ttgcatgttg gaatgatggt ggatatggtc acgtagcggt
    18481 tgttacagct gttgaatcaa caacacgtat ccaagtatca gaatcaaatt atgcaggtaa
    18541 tcgtacaatt ggaaatcacc gtggatggtt caatccaaca acaacttctg aaggttttgt
    18601 tacatatatt tatgcagatt aatttacaga gggactcgaa tagagccctc ttttcaggtt
    18661 ttaccgtgac aatccctatt aaaaattata tcaaaatagc ttgaaaatat tggaaaagta
    18721 tggtaaaatg aaaattgtcg tgtgaacgat aatactcatt cttgatgaat tgtgaagcag
    18781 ttgcccttgg gtcgttttgc gagttgaagt caagaagagg aaaaaaacaa aaaggagaaa
    18841 tactcatggc agtaatttca atgaaacaac ttcttgaggc tggtgtacac tttggtcacc
    18901 aaactcgtcg ctggaatcct aagatggcta agtacatctt tactgaacgt aacggaatcc
    18961 atgttatcga cttgcaacaa actgtaaaat acgctgacca agcatacgac ttcatgcgtg
    19021 atgcagcagc taacgatgca gttgtattgt tcgttggtac taagaaacaa gcagctgatg
    19081 cagttgctga agaagcagta cgttcaggtc aatacttcat caaccaccgt tggttgggtg
    19141 gaactcttac aaactgggga acaatccaaa aacgtatcgc tcgtttgaaa gaaattaaac
    19201 gtatggaaga agatggaact ttcgaagttc ttcctaagaa agaagttgca cttcttaaca
    19261 aacaacgtgc gcgtcttgaa aaattcttgg gcggtatcga agatatgcct cgtatcccag
    19321 atgtgatgta cgtagttgac ccacataaag agcaaatcgc tgttaaagaa gctaaaaaat
    19381 tgggaatccc agttgtagcg atggttgaca ccaatactga tccagatgat atcgatgtaa
    19441 tcatcccagc taacgatgac gctatccgtg ctgttaaatt gatcacagct aaattggctg
    19501 acgctattat cgaaggacgt caaggtgagg atgcagtagc agttgaagca gaatttgcag
    19561 cttcagaaac tcaagcagat tcaattgaag aaatcgttga agttgtagaa ggcgacaacg
    19621 cttaatttat acaaatagta attacctagg agggcggggc ttagcccggc tctcctattt
    19681 tcaaaaaata taggagaatt aaaatggcag aaattacagc taaacttgta aaagagttgc
    19741 gtgaaaaatc tggtgccggt gttatggacg ctaaaaaagc gcttgtagaa acagacggtg
    19801 acatcgaaaa agcgattgaa ttgcttcgtg aaaaaggtat ggctaaggca gctaagaaag
    19861 ctgaccgtgt tgctgcagaa ggtttgactg gtgtttatgt taacggtaat gttgcagcag
    19921 ttattgaagt aaacgctgaa actgacttcg ttgcaaaaaa cgctcaattc gttgaattgg
    19981 taaatactac agctaaagtc attgctgaag gaaaacctgc taacaacgaa gaagctcttg
    20041 ctttgataat gccttcaggt gaaactcttg aagctgcata cgtatctgca acagcaacta
    20101 tcggagagaa aatctcattc cgtcgctttg cattgattga aaaaacagac gcacaacact
    20161 ttggagcata ccaacataac ggtggacgta tcggtgttat ttcagttgtt gaaggtggag
    20221 acgaagcact tgctaaacaa ttgtcaatgc acatcgcagc gatgaaacca acagttcttt
    20281 cttacaaaga attggatgag caattcgtta aagatgagtt ggcacaattg aatcacgtta
    20341 tcgaccaaga caacgaaagc cgtgcaatgg ttaataaacc agctcttcca cacttgaagt
    20401 atggatcaaa agctcaatta actgatgatg ttattgctca agctgaagct gacatcaaag
    20461 ctgaattggc tgcagaaggc aaaccagaaa aaatctggga caaaattatt ccaggtaaaa
    20521 tggatcgctt catgcttgat aacactaaag ttgaccaagc ttacacactt cttgcacaag
    20581 tttacatcat ggatgacagc aagacagttg aagcatacct tgaatcagtt aacgcttcgg
    20641 tagttgagtt tgctcgcttt gaagttggtg aaggtatcga gaaagctgca aacgacttcg
    20701 aagctgaagt tgcagctaca atggcagcag ccttgaataa ctaataatag aaaggaagca
    20761 aattgcttcc ttttttgtat agggcttaga tttttcctga aattgttttt tccccagtct
    20821 cactcgatta gaataattaa aacaaaaagc cctataataa gggctaagtg catttaggag
    20881 actatacttc aaattcatag taagcgcgtt cataacaagg tatctatcct aattccccaa
    20941 cttccagtat actagataaa aaataattat cggagtaaag gtattgtact atgataattc
    21001 aactaagtga tttaggtcaa gttcaccttg tttgtggcaa gacagatatg aggtagggaa
    21061 tagactcatt agcctatgta gttaaaaccc actttgaatt ggattctttc tccggtcaag
    21121 tctttctctt ttgtggtgaa cgtaaagacc gctttaaagc cctttactgg gatggtcaag
    21181 gattttggct actatataaa cgctttgaga acggaaaact gacttggcta agtacagaaa
    21241 aggatgtcaa agctctcgca cctgaacaag tagattggct tatgaagggc ttttctatca
    21301 ctccaaaata tagtatattg aaactagaat agtacacctc tgcttctaaa acattgttag
    21361 aaatcgattt gactgtcctg atcgatttat cctgttctta tttcatttta ctataaatct
    21421 atcagaaagt tgtgatttct attgaaatga ggactttctt tttacactca tctgctttca
    21481 aaaagcattc tagtccgtct ccgattaacg atggacttta tcacctcctt ctccagtcct
    21541 tgtatgacat cttccaaagt tcgaaaggct ttattcttaa atccacgttt acgaatctct
    21601 ttccacactt gttcaatggg gttcatctct ggtgtgtatg gaggaataaa tgcaaagcca
    21661 atattagtcg gaatctttaa ggtacttgat ttatgccata tagcattgtc cataacgagt
    21721 aaaagataat catctggata agcttgtgaa atctcctatt cctaaagccc ctttagcgca
    21781 taactttggc tcagcttcta ttatcgctca caccatccat cagaagttta atctgaaggt
    21841 acccaattat cgccaagaag aagattgggc taggatgggt ttaccaatca tacgtaagga
    21901 aatctctaat tggcatatca agacgagtca atactatttg gagccccttt ataacctctt
    21961 gcgagagaga ctattgactc agcccttact tcatgcggat gaaacttctt atagggtgct
    22021 agagagtgat agtcagctga cttactactg gacttttttg tctgggaaag ctgagaaaca
    22081 agggattacg ctttaccatc atgtcctaat cgatttgttc atatcttatt tcaatccatt
    22141 ataaatagtg agaaatatct atcctatctt ctagaatgtc ttccaaacgt ggaaactctc
    22201 gtaaacaaag aggttttaga ggcctattta ccatggacta aagttgtaca agaaaagtgc
    22261 aaataagaaa tctccagatt aggaactatc cgtgagttct ctagtctgga gatttttcaa
    22321 tagacttcgt tattggacgg ttacaattca taaagtgctg tagagagata acgttcaccg
    22381 ttatctggtg ctagggcaag gactttttta cctgtaccta attttttggc aacctcgatg
    22441 gctccgtaga tagctgcagc tgaggaaatc cctacaagga agccttcttt tccaccaatt
    22501 tcacgtccga gtgcaagagc gtcatctgat gttacacgaa cgataccatc ataggcttta
    22561 gtatcaagtg tatcaggaat aaatccagct gagatacctt gaattttgtg aggaccaggt
    22621 ttttcaccag atagaatagc agattcatct gcttctactg caaaaacttg aatgttagaa
    22681 ttttctgatt tgagtgcatg agaaacacca gaaatcgttc caccagtacc tactccagca
    22741 acaaaggcat ctaatccatc tttaccgaaa gcagctagta tctcagctcc tgttgttctt
    22801 tcgtgtactt ctggattagc tggattgtca aattgaagag gaaggaaacc atcacgttca
    22861 gcagcgattt cttgagcctt agcaatagca cctttcattc cctcgctacc aggagttagg
    22921 acgagttcag caccataagc ttggataatt ttacgtcgtt ctacactcat agtttcaggc
    22981 ataacgatga cgactttata ccctttagca gcacctaccc atgaaagtcc aataccggtg
    23041 tttccacttg ttgcttcaac aatagtagaa ccaagtttca gaataccatc ttgttcagct
    23101 ttttcaatca tgctaagggc aatacggtct tttacagatg aaccaggatt aaatgcttca
    23161 agctttatat agacgtctgc agcaccttct ggcacgatgt tgttaagttt aacaatcggt
    23221 gtttgaccga ttaattcagt aatgttgtta taaatagaca tatgaatacc tctttgtata
    23281 agatatcttt agtataacgc tatccatacc atttgtaaaa tatagaaatc ctatcgaagc
    23341 gataggattt ctatatatca tagatcaaag tcattaattt tcaagtgatt gcgttcagtt
    23401 aattctagta aataggtgtg aaggaaaacg atatcaggtt tcgtttgaat tgcttcattt
    23461 tctagtatat tttggtacgc atctttttat tttgctcgct aaagtagttg tgagaatgtc
    23521 aacgaaacgc tgtattattc attgtttaca ctaagtttac agaaacttca acctctcgta
    23581 aaccttggtc agttaaagtg acttttccat taaaaaactc cacaagtgca gctttaatag
    23641 tttctttttc ttctttatca acataaatca tcgtatcgac ttgatctgta aagtttgtat
    23701 ccagctccat gagatcatgt tctttaagga agttactgta ctcttggtac tgagcataag
    23761 acatttgaat agcaatgcca gcctgttctt ttatttcaat aataccaatt tctttgacag
    23821 ctaaggcgac actgccggcg taagcacgaa ttagtcctcc agcgcctagt ttaataccac
    23881 caaagtagcg tgtcacgacc acacagacat tggtgagatt gtgattttct agtaccccaa
    23941 gcatgggaac accagcagta ccactaggct caccatcatc acttgtacgt ttaatttcac
    24001 tacgttctcc aataataaag gcagagcagt tatgtgtcgc tttgtagtgt tcttttttga
    24061 tggcagtaat gaagtcacga gcctcttctt cgctataaac acgcttggca tggcagataa
    24121 agcgagattt tttgatttct tcttggactt ggccgtcctc tttaattgtc ctaaattcca
    24181 tgatttaatt gtactaaaaa ataatctaaa gtgctagttt ttacgaataa agaagtatga
    24241 aagtaaattt agattatctc ggtcgtttat ttactgagaa tgaattaaca gaagaagaac
    24301 gtcagttggc ggagaaactt ccagcaatga gaaaggagaa ggggaaactt ttctgtcaac
    24361 gttgtaatag tactattcta gaagaatggt atttgcccat cggtgcttac tattgtcgag
    24421 agtgcttgct gatgaagcga gtcagaagtg atcaaacttt atactatttt ccgcaggagg
    24481 attttccgaa gcaagatgtt ctcaaatggc gcggccaatt aactcctttt caagagaagg
    24541 tgtcagaggg actgcttcaa gcagtagaca agcaaaagcc aaccttagtt catgcggtaa
    24601 caggagctgg aaagacagaa atgatttatc aagtagtggc taaagtgatc aatgcgggtg
    24661 gtgcagtgtg tttggctagt cctcgcatag atgtttgttt ggagctgtac aagcgcctgc
    24721 aacaggattt ttcttgcggt atagctttgc tacatggaga atcggaacct tattttcgaa
    24781 caccactagt tgttgcaaca acccatcagt tattgaagtt ttatcaagct tttgatttgc
    24841 tgatagtgga tgaagtagat gcttttcctt atgttgataa tcccacgctt taccacgctg
    24901 tcaagaatag tgtaaaggag aatggattga gaatcttttt aacagcgact tcgaccaatg
    24961 agttagataa aaaggtccgt ttaggagaac taaaaagact gagtttaccg agacggtttc
    25021 atggaaatcc gttgattatt ccaaaaccaa tttggttatc ggattttaat cgctacttag
    25081 acaagaatcg tttgtcacca aagttaaagt cctatattga gaagcagaga aagacagctt
    25141 atccgttact catttttgct tcagaaatta agaaagggga gcagttagaa gaaatcttac
    25201 aggagcaatt tccaaatgag aaaattggct ttgtatcttc tgtaacagag gatcgattag
    25261 agcaagtaca agcttttcga gatggagaac tgacaatact tatcagtacg acaatcttgg
    25321 agcgtggagt taccttccct tgtgtggatg ttttcgtaat agaggccaat catcgtttgt
    25381 ttaccaagtc tagtttgatt cagattggtg gacgagttgg acgaagcatg gatagaccga
    25441 caggagattt gcttttcttc catgatgggt taaatgcttc aatcaagaag gcgattaagg
    25501 aaattcagat gatgaataag gaggctggtc tatgaagtgc ttgttatgtg ggcagactat
    25561 gaagactgtt ttaactttta gtagtctctt acttctgagg aatgatgact cttgtctttg
    25621 ttcagactgt gattctactt ttgaaagaat tggggaagag aactgtccaa attgtatgaa
    25681 aacagagttg tcaacaaagt gtcaagcttg tcaattttgg tgtaaagaag gagttgaagt
    25741 cagtcataga gcgattttta cttacaatca agctatgaag gattttttca gtcggtataa
    25801 gtttgatgga gacttcctgt taagaaaagt tttcgcttca tttttaagtg aggagttgaa
    25861 aaagtacaaa gagtatcaat ttgttgtaat tcccctaagt cctgatagat atgctaacag
    25921 aggatttaat caggttgagg gcttggtaga ggcagcaggc tttgagtatc tagatttatt
    25981 agagaaaaga gaagagagag ccagttcttc taaaaatcgt tcagagcgct tggggacaga
    26041 acttcctttc tttattaaaa gtggagtcac tattcctaaa aaaatcctac ttatagatga
    26101 tatctatact acaggagcaa ctataaatcg tgttaagaaa ctgttggaag aagctggtgc
    26161 taaggatgta aaaacatttt cccttgtaag atgaggaaaa aatttgcaaa aatagaatga
    26221 aagcgttata ataaaatcat aaaaacaaaa atgtttagaa agaaggtact catatgatta
    26281 aatatagtat ccgtggtgaa aacctagaag taacagaagc aattcgtgat tatgtagttt
    26341 ctaaactcga aaagatcgaa aagtacttcc aaccagaaca agagttggat gcccgaatta
    26401 acttaaaagt ttatcgtgaa aaaacggcta aagtggaagt aacgattccg cttggatcta
    26461 ttactctccg cgcagaagat gtatctcaag atatgtatgg ttcaattgac cttgtaactg
    26521 ataaaattga acgtcagatt cgtaaaaata aaacaaaaat cgagcgtaaa aataaaaata
    26581 aggtagcaac tggtcaatta tttacagatg ctttggtgga agattcaaat attgtccagt
    26641 ctaaagttgt tcgttcaaaa caaattgatt taaaaccaat ggatttggaa gaagcaattc
    26701 tacaaatgga tttattgggg catgatttct ttatctatgt ggatgttgaa gatcagacaa
    26761 ccaatgtgat ttatcgtcgt gaggatggcg aaattggttt gttagaggtt aaagaatctt
    26821 aatttcaata tgtgtaaagg taggtttact gaattgtaaa ctaccttttt cttataattg
    26881 atagaattac tgattacact tttaaaaagt cgctttttga ggggtattat ggtataatgg
    26941 gtgccaagag gttttgaatg aaaaaatttt atgtaagtcc aatttttcct attctagtag
    27001 gattgattgc gtttggagtc ttatccactt tcattatttt tgttaataat aatctgttga
    27061 cggttttaat tttgtttctt tttgtaggag gctatgtttt tttatttaag aaactgagag
    27121 tgcattatac aaggagtgat gtagaacaga tacagtatgt aaaccaccaa gcggaagaaa
    27181 gtttgacagc tctattggaa cagatgcctg taggtgttat gaaattgaat ttatcttctg
    27241 gagaggttga gtggtttaat ccctatgctg aattgatttt gaccaaggaa gatggtgatt
    27301 ttgatttaga agctgttcaa acgattatca aggcttcagt aggaaatccg tctacttatg
    27361 ccaagcttgg tgagaagcgt tatgctgttc atatggatgc ttcttccggt gttttgtatt
    27421 ttgtagatgt atccagggaa caagccataa cagatgaatt ggtaacaagt cgaccagtga
    27481 ttgggattgt ctctgtggat aattatgatg atttggagga tgcaacttct gagtcagata
    27541 ttagtcaaat caatagtttt gtagctaatt ttatatcaga gttttcagaa aaatacatga
    27601 tgttttctcg tcgggtaagt atggatcgat tttatctatt tactgactac acggtgcttg
    27661 agggcttgat gaatgataaa ttttctgtta ttgatgcttt cagagaagag tcgaaacaga
    27721 gacagttgcc cttgacctta agtatgggat tttcttatgg cgatggaaat catgatgaga
    27781 tagggaaagt tgctttgctc aatttgaact tggctgaagt acgtggtggc gaccaggtgg
    27841 ttgttaagga aaacgacgaa acgaaaaatc cagtttattt tggtggtggg tctgctgctt
    27901 caatcaagcg tacacggact cgtacgcgcg ctatgatgac agctatttca gataagattc
    27961 ggagtgtaga tcaggttttt gtagtcggtc acaaaaattt agacatggat gctttgggct
    28021 ctgctgtagg tatgcagttg ttcgccagca atgtgattga aaatagctat gctctttatg
    28081 atgaagaaca aatgtctcca gatattgaac gagctgtttc attcatagaa aaagaaggag
    28141 ttacgaagtt gttgtctgtt aaggatgcat tggggatggt gaccaatcgt tctttgttga
    28201 ttcttgtaga ccattcaaag acagccttaa cattatcaaa agaattttat gatttattta
    28261 cccaaaccat tgttattgac caccatagaa gggatcagga ttttccagat aatacggtca
    28321 ttacttatat cgaaagtggt gcaagtagtg ccagtgagtt ggtaacggaa ttgattcagt
    28381 tccagaattc taagaaaaat cgtttgagtc gtatgcaagc aagtgtcttg atggctggta
    28441 tgatgttgga tactaaaaat ttcacctcgc gagtaactag tcggacattt gatgttgcta
    28501 gctatctcag aacgcgcgga agtgatagta ttgctatcca ggaaatcgct gcgacagatt
    28561 ttgaagaata tcgtgaggtc aatgaactta ttttacaggg gcgtaaatta ggttcagatg
    28621 tactaatagc agaggctaag gacacgaaat gctatgatac agttgttatt agtaaggcag
    28681 cagatgccat gttagccatg tcaggtattg aagcgagttt tgttcttgcg aagaatacac
    28741 aaggatttat ctctatctca gctcgaagtc gtagtaaact gaatgtacaa cggattatgg
    28801 aagagttagg cggtggaggc cactttaatt tggcagcagc tcaaattaaa gatgtaacct
    28861 tgtcagaagc aggtgaaaaa ctgacagaaa ttgtattaaa tgaaataaag gaaaaggaga
    28921 aagaagaatg aaagtaatct ttttagcaga tgttaaagga aaaggtaaaa aaggcgaaat
    28981 taaggaagta ccaacagggt atgcgcaaaa ctttcttatc aaaaagaatc tagccaaaga
    29041 agcgactgct caagctgtag gtgaacttcg tggtaaacaa aaatcggaag aaaaagctca
    29101 cgctgagatg attgcagaag gaaaagcaat taaagcacaa cttgaagcag aagaaactgt
    29161 tgtagaattt gttgaaaaag ttggtccaga tggtcgtacc tttggctcta ttaccaataa
    29221 gaagattgca gaagaattgc aaaaacaatt tggaattaag attgataaac gtcatattca
    29281 agtacaagct ccgattcgag cggttggttt gattgatgtg ccagtgaaaa tctatcaaga
    29341 tatcacaagt gtaatcaatc ttcgtgtgaa agaaggataa gtttacacct tcttgacaag
    29401 attgtaaaag gaagggaagt ctgatggcag aagtagaaga gttacgagta caacctcaag
    29461 atatcttagc tgagcaatcc gttttagggg ctatctttat tgatgagagt aaacttgttt
    29521 ttgtgcgaga atacattgag tctcgggact tttttaagta tgcccatcgt ttgattttcc
    29581 aagccatggt cgatttatcc gatcgtggtg atgccataga tgcaacaacg gttcgtacta
    29641 tccttgataa tcaaggtgat ttacagaata ttggtggctt gtcttacttg gttgagattg
    29701 ttaattctgt gccaacttct gctaatgcgg agtattatgc taagattgtt gcagaaaaag
    29761 caatgctacg tcgtttaatt gccaagttga cagagtctgt caaccaagct tacgaagcgt
    29821 cacaaccagc tgatgaaatt attgctcagg cagaaaaagg gctgattgat gtcagtgaaa
    29881 atgcaaatcg aagcgggttt aagaacattc gagatgtgtt gaatctcaac tttggaaatc
    29941 tggaagctcg ctcgcaacaa acgaccgata ttacaggtat tgcgacaggt tatcgtgatt
    30001 tggatcatat gacaacagga cttcatgagg aggagttgat tatcttagca gctcgtccag
    30061 cagttggtaa gacagcattt gccttgaata tcgctcagaa cattgggact aagttggaca
    30121 aaacggttgc tattttttca ctcgaaatgg gtgcggaaag cttggtagat cgtatgttag
    30181 ctgcagaagg cttagtggag tcacattcta tccgtacagg gcaattgaca gatgaggagt
    30241 ggcaaaaata tactattgct cagggtaatc tagctaacgc cagtatctat atcgatgata
    30301 cgccaggtat tcggattaca gagattcgtt ctcgttctcg taaattggct caagaaactg
    30361 gaaatcttgg tttgattttg atagactatt tgcaacttat cacgggaact ggtcgagaaa
    30421 atcgtcaaca agaagtttct gaaatttctc gtcagttgaa aatactagcc aaggaattga
    30481 aggttccagt aatcgctctg agtcagcttt ctcgtggtgt agaacaacgt caggacaaga
    30541 gaccggtctt gtctgatatt cgtgaatctg ggtctattga gcaggacgct gatatcgtag
    30601 cttttctcta tcgcgatgac tactatgaac gtggtggtga agaagaggag ggtatcccaa
    30661 ataataaggt ggaagttatt atcgagaaaa accgtagtgg agctcgtgga acagtggaat
    30721 tgattttcca aaaagaatac aataaatttt caagtatctc aaagagggag gcataagatg
    30781 tcagatgcat ttacagatgt agccaagatg aaaaaaatca aagaagaaat caaggcacat
    30841 gagggacaag tcgtagaaat gactttggag aatggtcgta agcgccaaaa aaatagattg
    30901 ggtaagctaa ttgaagttta tccatctcta tttattgtgg agtttgggga tgtggaagga
    30961 gataaacaag ttaatgttta cgttgaatcc tttacttact cagatattct tacagaaaag
    31021 aatttgattc attatcttga ctaaagtgag aaattttctc actttttctt ttttctccga
    31081 ataatttagg tgaaggcaat catcgcttta tattattttt caaggaggaa gaatgaaaat
    31141 tttaccgttt atagcaagag gaacaagtta ttacttgaag atgtcagtta aaaagcttgt
    31201 tcctttttta gtagtaggat tgatgctagc agctggtgat agtgtctatg cctattccag
    31261 aggaaatgga tcgattgcgc gtggggatga ttatcctgct tattataaaa atgggagcca
    31321 ggagattgat cagtggcgca tgtattctcg tcagtgtact tcttttgtag cctttcgttt
    31381 gagtaatgtc aatggttttg aaattccggc agcttatgga aatgcgaatg aatggggaca
    31441 tcgtgctcgt cgggaaggtt atcgtgtaga taatacaccg acgattggtt ccattacttg
    31501 gtctactgca ggaacttatg gtcatgttgc ctgggtgtca aatgtaatgg gagatcagat
    31561 tgagattgag gaatataact atggttatac agaatcctat aataaacgag ttataaaagc
    31621 aaacacgatg acaggattta ttcattttaa agatttggat ggtggcagtg ttgggaatag
    31681 tcaatcctca acttcaacag gcggaactca ttattttaag accaagtctg ctattaaaac
    31741 tgaaccccta gttagtgcaa ctgtgattga ttactattat cctggagaga aggttcatta
    31801 tgatcaaatt ctcgaaaaag acggctacaa gtggttgagt tatactgcct ataatggaag
    31861 ctatcgttat gttcaattgg aggctgtgaa taaaaatcct ctaggtaatt ctgttctttc
    31921 ttcaacaggt ggaactcatt attttaagac caagtctgct atcaaaactg aacccctagt
    31981 tagcggaact gtgattgatt actattatcc tggggagaag gttcattatg atcagatact
    32041 tgaaaaagac ggctacaagt ggttgagtta tactgcctat aatggaagtc gtcgctatat
    32101 acagctagag ggagtgactt cttcacaaaa ttatcagaat caatcaggaa atatctctag
    32161 ctatggatcc aataatagtt caactgtcgg ttggaagaaa ataaatggta gttggtatca
    32221 tttcaaatca aatggttcta aatcaacagg atggctgaaa gacggttcta gctggtatta
    32281 tttgaaatta tctggtgaaa tgcagacagg atggttaaag gagaatggct cgtggtatta
    32341 tctgggtagt tcaggggcaa tgaaaacagg ctggtaccag gtctctggta agtggtatta
    32401 ttcttactct tcaggcgcct tagctgttaa tacgacggtg gatggctaca gagtaaacag
    32461 tgatggagaa cgagtataga aaattggagt aggagaaatt tcctgctctt ttctgtaagc
    32521 agtttccttg acatttttct tattttgcgc tatcatatat acatataata tatgggagtc
    32581 tgtgtacagt ctgagaggaa gtgttaaact tcgaccgcac ctgatctggg taatgccagc
    32641 ggagggaacg atacttagtc taattttgca ccttttccat gtatggtaaa ggtttttctt
    32701 ttttttaaaa ggaaaacgag aagaggaggt tcttatgaaa gcaagcattg ccttgcaagt
    32761 tttaccccta gcacagggga ttgatcggat agctgttatt gatcaggtca ttgcttatct
    32821 gcaaactcaa gaagtgacga tggtagtgac accatttgaa acggtcttgg aaggggagtt
    32881 tgatgagctt atgcgcattc taaaagaagc gctggaagtg gcagggcagg aggcagacaa
    32941 tgtctttgcc aatgtcaaaa taaatgtagg agagatttta agtattgatg agaaacttga
    33001 aaagtatact gagacgacac attagtctat tgggctttct cggagtattg tcaatctggc
    33061 agttagcagg ttttcttaaa cttctcccca agtttatcct gccgacacct cttgaaattc
    33121 tccagccctt tgttcgtgac agagaatttc tctggcacca tagctgggcg accttgagag
    33181 tggctttact ggggctgatt ttgggagttt tgattgcctg tcttatggct gtgctcatgg
    33241 atagtttgac ttggctcaat gacctgattt accctatgat ggtggtcatt cagaccattc
    33301 cgaccattgc catagctcct atcctggtct tgtggctggg ttatgggatt ttgcccaaga
    33361 ttgtcttgat tatcttaaca acaacctttc ccatcatcgt tagtattttg gacggtttta
    33421 ggcattgtga caaggatatg ctgactttgt ttagtctgat gcgagcaaac ccttggcaaa
    33481 tcctgtggca ttttaaaatc ccggttagcc tgccttactt ttatgcaggt ctgagggtca
    33541 gtgtctccta cgcctttatc acaactgtgg tatctgagtg gttgggaggt tttgaaggtc
    33601 ttggtgttta tatgattcag tctaaaaaac tgtttcagta tgataccatg tttgccatta
    33661 ttattctggt gtcgattatc agtcttttgg gtatgaagct ggtcgatatc agtgaaaaat
    33721 atgtgattaa atggaaacgt acttaaaata gagcgttttt gaaaaagaaa agaggaaatc
    33781 aaaatgaaga aaacatggaa agtgttttta acgcttgtaa cagctcttgt agctgttgtg
    33841 cttgtggcct gtggtcaagg aactgcttct aaagacaaca aagaggcaga acttaagaag
    33901 gttgacttta tcctagactg gacaccaaat accaaccaca cagggcttta tgttgccaag
    33961 gaaaaaggtt atttcaaaga agctggagtg gatgttgatt tgaaattgcc accagaagaa
    34021 agttcttctg acttggttat caacggaaag gcaccatttg cagtgtattt ccaagactac
    34081 atggctaaga aattggaaaa aggagcagga atcactgccg ttgcagctat tgttgaacac
    34141 aatacatcag gaatcatctc tcgtaaatct gataatgtaa gcagtccaaa agacttggtt
    34201 ggtaagaaat atgggacatg gaatgaccca actgaacttg ctatgttgaa aaccttggta
    34261 gaatctcaag gtggagactt tgagaaggtt gaaaaagtac caaataacga ctcaaactca
    34321 atcacaccga ttgccaatgg cgtctttgat actgcttgga tttactacgg ttgggatggt
    34381 atccttgcta aatctcaagg tgtagatgct aacttcatgt acttgaaaga ctatgtcaag
    34441 gagtttgact actattcacc agttatcatc gcaaacaacg actatctgaa agataacaaa
    34501 gaagaagctc gcaaagtcat ccaagccatc aaaaaaggct accaatatgc catggaacat
    34561 ccagaagaag ctgcagatat tctcatcaag aatgcacctg aactcaagga aaaacgtgac
    34621 tttgtcatcg aatctcaaaa atacttgtca aaagaatacg caagcgacaa ggaaaaatgg
    34681 ggtcaatttg acgcagctcg ctggaatgct ttctataaat gggataaaga aaatggtatc
    34741 cttaaagaag acttgacaga caaaggcttc accaacgaat ttgtgaaata atgacagaaa
    34801 ttagactaga gcatgtcagt tatgcctatg gtcaggagag gattttagag gatatcaacc
    34861 tacaggtgac ttcaggcgaa gtggtttcca ttctaggccc aagtggtgtt ggaaagacca
    34921 ccctctttaa tctaatcgct gggattttag aagttcagtc agggagaatt gtccttgatg
    34981 gtgaagaaaa tcccaagggg cgcgtgagtt atatgttgca aaaggatctg ctcttggagc
    35041 acaagacggt gcttggaaat atcattctgc ccctcttgat tcaaaaggtg gataaggcag
    35101 aagctatttc ccgagcggat aaaattcttg cgaccttcca gctgacagct gtaagagaca
    35161 agtatcctca tgaacttagc ggtgggatgc gccagcgtgt agccttactc cggacctacc
    35221 tttttgggca caagctcttt ctcttagatg aggcctttag cgccttggat gagatgacaa
    35281 agatggaact ccacgcttgg tatcttgaga ttcacaaaca gttgcagcta acaaccctga
    35341 tcatcacgca tagtattgag gaggccctca atctcagcga ccgtatctat atcttgaaaa
    35401 atcgccctgg gcagattgtt tcagaaatta aactagattg gtctgaagat gaggacaagg
    35461 aagtccaaaa gattgcctac aaacgtcaaa tcttggcaga attaggctta gataagtaga
    35521 aaaataggga gttggtgaag attatccttt accagcgccc tttttctttt aaaaatgaga
    35581 aaatttcggt ataatagtca aacaaggtca aggtttaaag agagaggtgg gtttgttatg
    35641 agatttaaaa atacatcgga tcatattgag gcctacatca aggcgatttt agatcaatct
    35701 ggtatcgtgg agttgcaacg gagtcagttg gcagatacct ttcaggttgt tcctagtcag
    35761 attaactacg tgatcaagac acgctttacg gaaagtagag gctacttggt tgaaagtaag
    35821 cgtggtggcg gaggctacat tcgtatagga cggattgagt tttctagtca tcatgaaatg
    35881 ctccgggagc tgctttactc gattggtgag cgagtcagtc aagaaattta tgaggatatt
    35941 ctccagcttt tggttgagca ggaattgatg accaagcagg agatgaattt gctagaatca
    36001 gtagctttgg atcgcgtttt aggagaagaa gctccagttg ttcgagcaaa catgctacgt
    36061 caggtcatac aagaggtaga tagaaaaggg aagtaagatg aactattcaa aagcattgaa
    36121 tgaatgtatc gaaagtgcct acatggttgc tggacatttt ggagctcgtt atctagagtc
    36181 gtggcacttg ttgattgcca tgtctaatca cagttatagt gtagcagggg caactttaaa
    36241 tgattatccg tatgagatgg accgtttaga agaggtggct ttggaactga ctgaaacgga
    36301 ctatagccag gatgaaacct ttatggaatt gccgttctcc cgtcgtttgc aggttctttt
    36361 tgatgaagca gagtatgtag cgtcagtggt ccatgctaag gtactaggga cagagcacgt
    36421 cctctatgcg attttgcatg atggcaatgc cttggcgact cgtatcttgg agagggctgg
    36481 tttttcttat gaagacaaga aagatcaggt caagattgct gctcttcgtc gaaatttaga
    36541 agaacgggca ggctggactc gtgaagatct caaggcttta cgccaacgcc atcgtactgt
    36601 ggctgacaaa caaaattcta tggccaatat gatgggcatg ccgcagactc ctagtggtgg
    36661 tctcgaggac tatacgcatg atttgacaga gcaagcgcgt tctggcaagt tagaaccagt
    36721 catcggtcgg gacaaggaaa tctcacgtat gattcaaatc ttgagccgta agactaagaa
    36781 caaccctgtc ttggttgggg atgctggtgt cgggaaaaca gctctggtgc ttggtcttgc
    36841 tcagcgtatt gccagtggtg atgtgcctgc ggaaatggct aagatgcgcg tgttagaact
    36901 tgatttgatg aatgtcgttg cagggacacg cttccgtggt gactttgaag aacgcatgaa
    36961 taatatcatc aaggatattg aagaagatgg ccaagtcatc ctctttatcg atgaactcca
    37021 caccatcatg ggttctggta gcgggattga ttcgactctg gatgcggcca atatcttgaa
    37081 accagccttg gcgcgtggag ctttgagaac ggttggtgcc accactcagg aagaatatca
    37141 aaaacatatc gaaaaagatg cggctctttc tcgtcgtttc gctaaagtga cgattgaaga
    37201 accaagtgtg gcagatagta tgactatttt acaaggtttg aaggcgactt atgagaaaca
    37261 tcaccgtgta caaatcacag atgaagcggt tgaaacagcg gttaagatgg ctcatcgtta
    37321 tttaaccagt cgtcacttgc cagactctgc tatcgacctc ttggacgaag cagcagcaac
    37381 agtgcaaaat aaggtaaagt atgtaaaagc agacgattca gatttgagtc cagctgataa
    37441 ggccctgatg gatggcaagt ggaaacaggc agcccagcta atcgcaaaag aagaggaagt
    37501 acctgtctac aaagacttgg tgacagagtc tgatattttg accaccttga gtcgcttgtc
    37561 aggaatccca gttcaaaaac tgactcaaac ggatgctaag aagtatctaa atcttgaagc
    37621 agaactccat aaacgtgtca tcggtcaaga tcaagctgtt tcaagcatta gtcgtgcgat
    37681 tcgccgtaat cagtcaggaa ttcgcagtca caagcgtccg atcggttcct ttatgttcct
    37741 aggacccaca ggtgtcggta agaccgagtt ggccaaggct ttggcagaag ttctctttga
    37801 tgacgaatca gcccttatcc gctttgatat gagtgagtat atggagaaat tcgcagccag
    37861 ccgtctaaat ggagctcctc caggctatgt gggttacgaa gaaggtggag agttgacaga
    37921 gaaggttcgc aataaaccct attccgttct cctctttgat gaggtagaga aggcccaccc
    37981 agatattttt aatgttctct tgcaggttct ggatgacggt gttttgacag atagcaaggg
    38041 acgcaaggtc gatttttcaa ataccattat cattatgaca tcgaacctag gtgcgactgc
    38101 ccttcgtgat gataagactg ttggttttgg ggctaaggat attcgttttg accaggaaaa
    38161 tatggaaaaa cgcatgtttg aagaactgaa aaaagcttat agaccggaat tcatcaaccg
    38221 tattgatgag aaggtggtct tccatagcct atctagtgac catatgcagg aagtggtgaa
    38281 gattatggtc aagcctttag tggcaagttt ggctgaaaaa ggcattgact tgaaattaca
    38341 agcttcagct ctgaaattgt tagcaaatca aggatatgac ccagagatgg gagctcgccc
    38401 acttcgcaga accctgcaaa cagaagtgga ggacaagttg gcagaacttc ttcttaaggg
    38461 agatttagtg gcaggcagca cacttaagat tggtgtcaaa gcaggccagt taaaatttga
    38521 tattgcataa aagaataaaa gtatcagcat ctgaccataa gtcacagtgg agtgaaactc
    38581 aatgaaaatc aaagagcaaa ctaggcagct agccgcaggt tgctcaaaac actggtttga
    38641 ggttgcagat agagctgacg tggtttgaag agattttcga agagtatgaa actaaaacct
    38701 atagcttcta aacgatccgt ggttttcacc attcaacaca aaattcatat gtttattacc
    38761 ctccgtcgta tttgtcttag agcgtgtgta gtagaaaaag agcagtctta tctgaaattt
    38821 ttattctttc aaaagagacc tgtttctttt ttgcatgtca aatccgttct agctggtatt
    38881 tgaaaaatca aactaatatt caatgaaaat caaagaacaa actaggcagc tagccacagg
    38941 ttgctcaaaa cactgttttg aggttgtaga tagagctgac gtagtttgaa gagattttcg
    39001 aagagtataa gctgcaagat gaatgatttt cttgtattga cgttgttgtt gacaaaaagt
    39061 agcggataaa tgaaatccat tccattatca tagatgatag gctggtagga aattttcaaa
    39121 tagcatacag gaaatagatg tatggagttc tggtagtaga aagggagaga gatgaacatt
    39181 ttagttgcag atgacgagga aatgattaga gaaggaattg cagcatttct gacagaagag
    39241 ggttatcatg tcattatggc taaggatgga caagaggtct tggaaaaatt tcaagatctc
    39301 cctatccatc tcatggtatt ggatttaatg atgcctagga agagtggttt tgaagtgtta
    39361 aaagaaatca atcaaaagca cgatattcct gtcatcgtct tgagtgctct gggagatgaa
    39421 actactcagt cacaggtatt tgatctctat gctgatgatc atgtgacaaa acctttttct
    39481 ttggtactgc ttgtcaagcg tattaaggcg cttatcagac gttactacgt catagaggat
    39541 atttggcgat atcaggatgt aacagtggat tttacctctt acaaagcaca ttataaaaat
    39601 gaagaaattg atctcaaacc aaaggaatta ctggtactaa agtgtttgat tcagcataaa
    39661 aatcaagttt taagtagaga gcagatattg gaagaaattt caaaagatgt agctgattta
    39721 ccttgtgata gggtcgttga tgtctatatt cgtactcttc gcaaaaaatt agctttagat
    39781 tgtatcgtga ctgtgaaaaa tgttgggtat aagattagct tatgataaaa aatcctaaat
    39841 tattaaccaa gtctttttta agaagttttg caattctagg tggtgttggt ctagtcattc
    39901 atatagctat ttatttgacc tttccttttt attatattca actggagggg gaaaagttta
    39961 atgagagcgc aagagtgttt acggagtatt taaagactaa gacatctgat gaaattccaa
    40021 gcttactcca gtcttattca aagtccttga ccatatctgc tcaccttaaa agagatattg
    40081 tagataagcg actccctctt gtgcatgact tggatattaa agatggaaag ctatcaaatt
    40141 atatcgtgat gttagatatg tctgttagta cagcagatgg taaacaggta acagtgcaat
    40201 ttgttcacgg ggtggatgtc tacaaagaag caaagaatat tttgtttttg tatcttccat
    40261 atacattttt ggttacaatt gctttttcct ttgttttttc ttatttttat actaaacgct
    40321 tgctcaatcc tcttttttac atttcagaag tgactagtaa aatgcaagat ttggatgaca
    40381 atattcgttt tgatgaaagt aggaaagatg aagttggtga agttggagaa gttggaaaac
    40441 agattaatgg tatgtatgag cacttgttga aggttattca tgagttggaa agtcgtaatg
    40501 agcaaattgt aaaattgcaa aatcaaaagg tttcctttgt ccgtggagca tcacatgagt
    40561 tgaaaacccc tttagccagt cttagaatta tcctagagaa tatgcagcat aatattggag
    40621 attacaaaga tcatccaaaa tatattgcaa agagtataaa taagattgac cagatgagcc
    40681 acttattgga agaagtactg gagtcttcta aattccaaga gtggacagag tgtcgtgaga
    40741 ccttgactgt taagccagtt ttagtagata ttttatcacg ttatcaagaa ttagctcatt
    40801 caataggtgt tacaattgaa aatcaattga cagatgctac cagggtcgtc atgagtctta
    40861 gggcattgga taaggttttg acaaacctga ttagtaatgc aattaaatat tcagataaaa
    40921 atgggcgcgt aatcatatcc gagcaagatg gctatctctc tatcaaaaat acatgtgcgc
    40981 ctctaagtga ccaagaacta gaacatttat ttgatatatt ctatcattct caaatcgtga
    41041 cagataagga tgaaagttcc ggtttgggtc tttacattgt gaataatatt ttagaaagct
    41101 atcaaatgga ctatagtttt ctcccttatg aacacggtat ggaatttaag attagcttgt
    41161 agacagatta gttttttatt aaagttcata tagggttaac ataagtgtgt tattctttgt
    41221 gtagataaaa gaaaggatac taatatggta ttagcgatta ttttagtaac attctttatt
    41281 cgattgattt ttttaaagcg ttcgatagag aatgagaaac gaatccttag caatggcggg
    41341 aaagaatttg gagttgagaa tacaaaacga ttaactatgg ctcatattgt tttttatctc
    41401 tcttgcttgg ttgaggcaat ggtgcacaag acaatttttg atggcatggg catggttggt
    41461 ttagtcttgc ttattttttc tatgctgatg ttaatgttgg tgattcactt gttgggagat
    41521 atttggacag tgaagcttat gcttgtcaat aatcacaaat atgtagatca tatcttgttt
    41581 aggacagtaa aacatcctaa ttacttttta aatattcttc ctgagttgat tggcttgacc
    41641 ttgttgagtc atgcttatgt gacttttgtt ttagtttttc cagtttatgc agttattttg
    41701 tatcgacgaa tagctgaaga ggaaaagcta ttacatgaag ttataatccc aaatggaagc
    41761 ataaagagat aaatacaaaa ttcgatttat atacagttca tattgaagtg atatagtaag
    41821 gttaaagaaa aaatatagaa ggaaataaac atgtttgcat caaaaagcga aagaaaagta
    41881 cattattcaa ttcgtaaatt tagtattgga gtagctagtg tagtagttgc tagcttgttc
    41941 ttaggaggag tagttcatgc agaaggggtt agaagtgggg atacccccaa ggttacatct
    42001 agtggggatg aagtcgagtc gcatctaaaa aaaatattga gtgagatcca aacacaatta
    42061 gatagaaaac gacatgccaa aactgtagcg ctaattaaca agttgcaaga cattaagaga
    42121 acgtattcgt ataaattaaa tgttttagaa gagaagccga aagctgagtt gacgtcaaaa
    42181 acaaaagaag agttaaccgc agcttttgag caatttaaaa aagatacatt accaacagaa
    42241 ccaggaaaaa aggtagcaga agctgagaag aaggttgcag aagctgagaa aaaagccgag
    42301 gatcaaaaag aagaagatcg tcgtaactac ccaaccaata cttacaaaac gcttgaactt
    42361 gaaattgctg agttcgatgt gaaagttaaa gaagcggagc ttgaactatt aaaagagaaa
    42421 gctaagaaac ctttaaacga gggcacaatt aagcaagcaa aagagaaagt tgagagtaaa
    42481 aaagctgagg ctacaaggtt agaaaacatc aagacagatc gtaaaaaagc agaagaagaa
    42541 gctaaacgaa aagcagcaga agaagataaa gttaaagaaa aaccagctga acaaccacaa
    42601 ccagcgccgg ctcctcaacc agaaaaacca gctccaaaac cagaaaaacc agctccagct
    42661 ccaaaaccag agaatccagc tccaaaacca gaaaaaccag ctccagctcc aaaaccagag
    42721 aatccagctg aacaaccaaa agcagaaaaa ccagctgatc aacaagctga agaagactat
    42781 gctcgtagat cagaagaaga atataatcgc ttgactcaac agcaaccgcc aaaaactgaa
    42841 aaaccagcac aaccatctac tccaaaaaca ggctggaaac aagaaaacgg tatgtggtac
    42901 ttctacaata ctgatggttc aatggcgaca ggatggctcc aaaacaatgg ctcatggtac
    42961 tacctcaaca gcaatggcgc tatggcgaca ggatggctcc aaaacaatgg ttcatggtac
    43021 tatctaaacg ctaatggttc aatggcaaca ggatggctcc aaaacaatgg
//
LOCUS       DAVBEM010000012        41712 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVBEM010000012 DAVBEM010000000
VERSION     DAVBEM010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41712
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.012"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            1..398
                     /locus_tag="VQ548_000672"
                     /pseudo
     CDS             1..398
                     /locus_tag="VQ548_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(443..1084)
                     /gene="plsY"
                     /locus_tag="VQ548_000673"
     CDS             complement(443..1084)
                     /gene="plsY"
                     /locus_tag="VQ548_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HET2653570.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            1220..3163
                     /gene="parE"
                     /locus_tag="VQ548_000674"
     CDS             1220..3163
                     /gene="parE"
                     /locus_tag="VQ548_000674"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HET2653571.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            3583..6054
                     /gene="parC"
                     /locus_tag="VQ548_000675"
     CDS             3583..6054
                     /gene="parC"
                     /locus_tag="VQ548_000675"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HET2653572.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            6186..7208
                     /locus_tag="VQ548_000676"
     CDS             6186..7208
                     /locus_tag="VQ548_000676"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HET2653573.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            7264..7968
                     /locus_tag="VQ548_000677"
     CDS             7264..7968
                     /locus_tag="VQ548_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2653574.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSDM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGFPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            8033..8722
                     /locus_tag="VQ548_000678"
     CDS             8033..8722
                     /locus_tag="VQ548_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HET2653575.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            8719..9642
                     /locus_tag="VQ548_000679"
     CDS             8719..9642
                     /locus_tag="VQ548_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HET2653576.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            9657..10301
                     /gene="pcp"
                     /locus_tag="VQ548_000680"
     CDS             9657..10301
                     /gene="pcp"
                     /locus_tag="VQ548_000680"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET2653577.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            10469..10699
                     /locus_tag="VQ548_000681"
     CDS             10469..10699
                     /locus_tag="VQ548_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HET2653578.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            10749..10829
                     /locus_tag="VQ548_000682"
     tRNA            10749..10829
                     /locus_tag="VQ548_000682"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10783..10785,aa:Tyr,seq:gta)
     gene            10839..10910
                     /locus_tag="VQ548_000683"
     tRNA            10839..10910
                     /locus_tag="VQ548_000683"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10871..10873,aa:Gln,seq:ttg)
     gene            11072..12274
                     /gene="rpsA"
                     /locus_tag="VQ548_000684"
     CDS             11072..12274
                     /gene="rpsA"
                     /locus_tag="VQ548_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HET2653579.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            12360..12857
                     /locus_tag="VQ548_000685"
     CDS             12360..12857
                     /locus_tag="VQ548_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HET2653580.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            12857..14512
                     /gene="dnaX"
                     /locus_tag="VQ548_000686"
     CDS             12857..14512
                     /gene="dnaX"
                     /locus_tag="VQ548_000686"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HET2653581.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            14540..14734
                     /locus_tag="VQ548_000687"
     CDS             14540..14734
                     /locus_tag="VQ548_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HET2653582.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            14884..15654
                     /gene="sufC"
                     /locus_tag="VQ548_000688"
     CDS             14884..15654
                     /gene="sufC"
                     /locus_tag="VQ548_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HET2653583.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITRLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            15682..16944
                     /gene="sufD"
                     /locus_tag="VQ548_000689"
     CDS             15682..16944
                     /gene="sufD"
                     /locus_tag="VQ548_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HET2653584.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKINYLERLESRGEGSAKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSYADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            16955..18181
                     /locus_tag="VQ548_000690"
     CDS             16955..18181
                     /locus_tag="VQ548_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2653585.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPASARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            18168..18608
                     /locus_tag="VQ548_000691"
     CDS             18168..18608
                     /locus_tag="VQ548_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HET2653586.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            18658..20070
                     /gene="sufB"
                     /locus_tag="VQ548_000692"
     CDS             18658..20070
                     /gene="sufB"
                     /locus_tag="VQ548_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HET2653587.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(20301..21542)
                     /locus_tag="VQ548_000693"
     CDS             complement(20301..21542)
                     /locus_tag="VQ548_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HET2653588.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITAYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFIDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            21645..22754
                     /locus_tag="VQ548_000694"
     CDS             21645..22754
                     /locus_tag="VQ548_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET2653589.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            23288..23635
                     /gene="ssrA"
                     /locus_tag="VQ548_000695"
     tmRNA           23288..23635
                     /gene="ssrA"
                     /locus_tag="VQ548_000695"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(23818..23905)
                     /locus_tag="VQ548_000696"
     tRNA            complement(23818..23905)
                     /locus_tag="VQ548_000696"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23869..23871),aa:Ser,seq:gga)
     gene            24067..24807
                     /locus_tag="VQ548_000697"
     CDS             24067..24807
                     /locus_tag="VQ548_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2653590.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNITVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            24804..25715
                     /gene="pfkB"
                     /locus_tag="VQ548_000698"
     CDS             24804..25715
                     /gene="pfkB"
                     /locus_tag="VQ548_000698"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HET2653591.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDVVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            25712..27664
                     /locus_tag="VQ548_000699"
     CDS             25712..27664
                     /locus_tag="VQ548_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2653592.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREASTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            27828..30053
                     /locus_tag="VQ548_000700"
     CDS             27828..30053
                     /locus_tag="VQ548_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET2653593.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(30098..30526)
                     /locus_tag="VQ548_000701"
     CDS             complement(30098..30526)
                     /locus_tag="VQ548_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653594.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            30664..31806
                     /locus_tag="VQ548_000702"
     CDS             30664..31806
                     /locus_tag="VQ548_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2653595.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWLIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRHDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     NYPDIFVFSDEENFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            31815..33029
                     /gene="thiI"
                     /locus_tag="VQ548_000703"
     CDS             31815..33029
                     /gene="thiI"
                     /locus_tag="VQ548_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HET2653596.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            33164..33988
                     /locus_tag="VQ548_000704"
     CDS             33164..33988
                     /locus_tag="VQ548_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2653597.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPGQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYFECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            34010..34749
                     /locus_tag="VQ548_000705"
                     /pseudo
     CDS             34010..34749
                     /locus_tag="VQ548_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            34762..35928
                     /locus_tag="VQ548_000706"
     CDS             34762..35928
                     /locus_tag="VQ548_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET2653598.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIGRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            36436..37929
                     /locus_tag="VQ548_000707"
     CDS             36436..37929
                     /locus_tag="VQ548_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET2653599.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            37942..38988
                     /locus_tag="VQ548_000708"
     CDS             37942..38988
                     /locus_tag="VQ548_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2653600.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLLVKSRFNEMFGDVILNEKEWKVSKWNEILTIRNGKNQKQVEDADGKFPIY
                     GSGGIMGYAKDWIVKKNSVIIGRKGNINKPILVRENFWNVDTAFGLEPVLEKINSEYL
                     FYFCQLYNFEKLNKAVTIPSLTKSDLLNISIPLPPLALQNEFADFVALVDKSQFACEI
                     AIKVWRNSLKFSII"
     gene            39018..>41712
                     /locus_tag="VQ548_000709"
     CDS             39018..>41712
                     /locus_tag="VQ548_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET2653601.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSDHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEI"
BASE COUNT        12654 a         7506 c         9240 g        12312 t
ORIGIN      
        1 gcgaaattat cgcctataat ctttcaactt cgcccaactt agaacaagta taaacaatgt
       61 tggaacaggc attcaaagag aagcactacg agaatacgat tctccatagt gaccaaggct
      121 ggcaatatca acacgattct tatcatcagt tcctagagag taagggaatt caagcatcca
      181 tgtcacgtaa gggaaacagc ccagacaatg gtatgatgga gtccttcttt gggattctga
      241 aatcggaaat gttttacggt tatgagaagt cgtttcagtc gcttaagcaa ttggaacaag
      301 ccattataga ctatattgat tactacaaca ataaacgaat taagataaaa ctaaaaggac
      361 ttagccctgt gcaatacaga actaaatcct tcggataaat taattgtcta acttttgggg
      421 tgcagttcac agaactggca ttttattttt taggatcttg atgggttagg ttcaatcccc
      481 aagggaccaa attttcagtt ttatttttga tacgagctat attgtcctta tgacgaatga
      541 taatcaaact agcaagtgct aagataatag cgatgaagag agagtcatag ttactcagga
      601 taaaaccaaa aagtggaaag agcagaaccc cgataacagc cgcgatcgat gctgtgacac
      661 tagacagtga aatcatactg ccaagataga gagctccaaa gaagataatc gcaaggtaga
      721 gacagaagat aggcgcaaat ccgaaaatta ctccagcact ggttgcgaca gccttaccac
      781 ctttaaatcc tgcaaagata gggaaggtat ggccgataac agccaaaagt ccaaagatga
      841 gaggagaaac gccttgtaga tgaaaaataa tcggaagcag cgttgctagg gttcctttga
      901 aaaagtcaat cacaaaggtt gccataccag ctttcttacc taaaatgcgg aaggtattgg
      961 tcgttccagt gttaccagaa ccatgctcgc gtagattgat ttgaaagaat acttgtccaa
     1021 tccagagacc agatggaatc gaacccagca gataggctag gattaataaa actattgtaa
     1081 tcatactcct attatatcat gaattgggaa agaaaagcag agaatctctg ctaaaattgt
     1141 cacatcggag aaagaaaaat tttgcaaaat ccttggaaaa cctgtagaat agtaaagatg
     1201 aacgaatagg aggttccttg tgtcaaaaaa ggaaatcaat attaacaatt ataatgatga
     1261 tgctattcag gtgctagaag ggttggatgc ggtccgaaaa cgtccaggga tgtatattgg
     1321 atcgaccgat ggcgctggtc ttcatcacct agtttgggaa atcgttgata atgcagtcga
     1381 tgaagccttg tctgggtttg gtgatcgtat cgatgtaacc atcaataaag acggtagtct
     1441 aacggttcaa gaccatggac gtgggatgcc gacaggtatg cacgctatgg gaattccaac
     1501 tgttgaggtt atctttacca ttcttcatgc cggagggaaa ttcggtcaag gtggctataa
     1561 gacatcaggt ggacttcacg gagtgggttc ttccgttgtt aacgcccttt ctagctggtt
     1621 agaagttgaa attacccgtg atggcgcagt ttacaagcaa cgtttcgaaa atggtggaaa
     1681 acctgtcacg actttgaaga aaatcggtac agcacccaag tctaaaacag gcaccaaagt
     1741 tacttttatg cctgacgcga ctatattttc tacgacagat ttcaagtaca ataccatttc
     1801 agagcgcctt aatgaatcag cctttctctt gaaaaatgtg accttgtctt taacggacaa
     1861 gcgaacagat gaagcgattg agttccacta tgagaatgga gtacaagatt ttgtttctta
     1921 tctcaacgaa gataaggaaa tcttgacgcc agttctttac tttgaagggg aagacaatgg
     1981 ttttcaagtg gaagtagccc tccagtacaa tgacggattc tcagataaca ttctatcctt
     2041 tgtcaataac gttcgcacca aggacggtgg aacgcacgag acaggactca agtctgccat
     2101 taccaaggtc atgaatgact atgcacgtaa aacaggtctt ctcaaggaaa aagataaaaa
     2161 ccttgaaggt tcagactatc gtgagggact agcggccgtt ctttctatct tagttcctga
     2221 agaacacttg cagtttgaag gacagaccaa ggataaacta ggaagccccc tagctcgccc
     2281 agttgtggat ggaatagtgg ctgataagtt gacctttttc cttatggaaa atggggaatt
     2341 agcttctaac ctcatccgca aggctatcaa ggcccgtgat gctcgtgaag cagcacgtaa
     2401 ggcgcgtgat gagagccgaa atgggaagaa aaacaagaaa gataagggct tgttgtctgg
     2461 gaaattgacc ccagcccaat ctaagaatcc tgctaagaat gaactctatc tagttgaggg
     2521 ggactctgcc ggtggttctg ccaaacaagg tcgtgaccgc aagttccagg ctattctacc
     2581 tcttcgtggt aaggttatca atacagccaa ggccaagatg gcggatatcc tcaaaaatga
     2641 agagatcaat accatgattt ataccattgg tgcgggtgtt ggagcagact tctctattga
     2701 agatgccaac tatgataaga tcattatcat gaccgatgcg gataccgacg gtgcccatat
     2761 ccagaccttg ctcttgacat ttttctaccg ttacatgcgt ccgctagtcg aggcaggtca
     2821 tgtctatatt gccctcccac ctctttacaa gatgtccaaa ggtaaaggaa agaaagaaga
     2881 agtggcctac gcttggacgg acggagaact agaagaactc cgtaaacagt tcggtaaagg
     2941 cgctaccctc caacgataca aaggacttgg tgagatgaat gcggaccagc tctgggaaac
     3001 aaccatgaac ccagaaacac gtaccctcat ccgtgtcaca attgaagatt tagcgcgcgc
     3061 cgaacgccgc gtcaatgttc tcatgggaga taaggtagaa ccacgccgta aatggattga
     3121 agataatgtc aagtttacgc tagaagaagc gacagtgttt taatgaaaga aaataatatg
     3181 ttagtaaact ggaaattaga gtcggatgtg aatgactatg tgaaaaagca gtttgaaaat
     3241 cttggtttga aaaaattgca ggattattaa tgaagaatct gctatgagtg cttatctcaa
     3301 agaggcgctt aagggagcgg ctaagacaca aactaagact aattttggaa aaccagattt
     3361 tcatattgaa aaatacaaac aggatagttt ggttacttat cgtaactgaa cacgggagga
     3421 attcccgtaa aatatctttt actgcataaa aacctactct acattctttg aaaggagttg
     3481 aacacgccct agatactgtg tgaaaaagat aaattctctt gtgagtttgc ttacttcaag
     3541 aattttctat tttcacttgg tattttatgg gctttgtatc ttatgtctaa cattcaaaac
     3601 atgtccctgg aggacatcat gggagagcgc tttggtcgct actccaagta cattattcaa
     3661 gaccgggctt tgccagatat tcgtgatggg ttgaagccgg ttcagcgccg tattctttat
     3721 tctatgaata aggatagcaa tacttttgac aagagctacc gtaagtcggc caagtcagtc
     3781 gggaacatca tggggaattt ccacccacac ggggattctt ctatctatga tgccatggtt
     3841 cgtatgtcac agaactggaa aaatcgtgag attctagttg aaatgcacgg taataacggt
     3901 tctatggacg gagatcctcc tgcggctatg cgttatactg aggcacgttt gtctgaaatt
     3961 gcaggttacc ttcttcagga tatcgagaaa aatacagttc cttttgcatg gaactttgac
     4021 gatacggaga aagaaccaac ggtcttgcca gcagcctttc caaacctctt ggtcaatggt
     4081 tcgactggga tttcggctgg ttatgccaca gacattcctc cccataattt agctgaggtc
     4141 atagatgctg cagtttacat gattgaccac ccaactgcaa agattgataa actcatggaa
     4201 ttcttgcctg gaccagactt ccctacaggg gctattattc agggtcgtga tgaaatcaag
     4261 aaagcttatg agactgggaa agggcgcgtg gttgttcgtt ccaagactga aattgaaaag
     4321 ctaaaaggtg gtaaggaaca aatcgttatt actgagattc cttatgaaat caataaggcc
     4381 aatctagtca agaaaatcga tgatgttcgt gttaataaca aggtagctgg gattgctgag
     4441 gttcgtgatg agtctgaccg tgatggtctt cgtatcgcta tcgaacttaa gaaagacgct
     4501 aatactgagc ttgttctcaa ctacttattt aagtacaccg acctacaaat caactacaac
     4561 tttaatatgg tggcgattga caatttcaca cctcgtcagg ttgggattgt tccaatcctg
     4621 tctagctaca tcgctcaccg tcgagaagtg attttggcgc gttcacgctt tgacaaagaa
     4681 aaggctgaga aacgtctcca tatcgtcgaa ggtttgattc gtgtgatttc gattttggat
     4741 gaagtcattg ctcttatccg tgcttctgag aataaggcgg acgccaagga aaacctcaaa
     4801 gttagctatg attttacgga agaacaggct gaggctatcg taactttgca actgtaccgt
     4861 ttgaccaata ccgatgtggt tgtcttgcag gaagaagaag cagagcttcg tgagaagatt
     4921 gctatgctgg cggctattat cggtgatgaa aggactatgt acaatctcat gaagaaagaa
     4981 cttcgtgagg tcaagaagaa atttgcaact cctcgtttga gttctttaga agacactgcg
     5041 aaagcaattg agattgatac agctagtctt atcgctgagg aagataccta cgtcagcgtg
     5101 accaaggcag gttacatcaa gcgtaccagt ccacgttcct ttgcggcttc caccttggaa
     5161 gaaattggca agcgtgatga tgaccgtttg atttttgttc aatctgccaa gacaacccag
     5221 cacctcttga tgttcacaag tcttggaaat gtcatctaca gaccaatcca tgagttggca
     5281 gatattcgtt ggaaggacat cggagagcat ctgagccaaa ccatcacaaa ctttgaaacg
     5341 aatgaagaaa tcctttatgt ggaagtactg gatcagtttg acgatgcgac aacctacttt
     5401 gcagtgactc gccttggtca aatcaaacgg gtagagcgaa aagaattcac tccatggcgg
     5461 acctatagat ctaagtctgt caagtatgct aagctcaaag acgatacaga tcagattgta
     5521 gcagtggctc cgattaaact agatgatgtt gtcttggtta gtcaaaatgg ttatgccctg
     5581 cgtttcaata tcgaagaggt tccggttgtc ggtgctaagg cagcaggtgt caaggctatg
     5641 aatttgaaag aagatgatgt cctccaatct ggctttatct gtaatacttc gtccttctac
     5701 ctcttgaccc agcgtggaag cttgaaacgt gtttctattg aggaaattct agcaaccagc
     5761 cgtgccaaac gaggattaca agtcttgcgt gagttgaaaa acaaaccgca tcgtgtcttc
     5821 ttggcaggag cagttgcaga gcaaggattt gttggcgatt tcttcagtac ggaagtggat
     5881 gtgaacgacc aaactctgct tgtccaatcc aataaaggaa caatctatga aagccgattg
     5941 caagacttga acttgtcaga acgcactagc aatggaagct tcatttctga cacgatttca
     6001 gatgaagaag tttttgacgc ttatcttcag gaagtagtta ctgaagataa ataagtgaaa
     6061 tgaagaatca gttctaagag ctggttttta ttggagaaat tttctgaaaa ttacaaaata
     6121 tacttgctat tttagaaaaa tagtgtagaa tataagaaat aggtttttag aataaggagt
     6181 ggaatatgac agtaacgatt gattgggaaa acctcggttt ttcctatatg aaattacctt
     6241 atcgctatct tgctcatttc aaaaatggac aatgggatca aggagagctt acagaggatg
     6301 caactttgca tatttcagag tcttctccaa gtcttcacta tggacaacaa gcatttgaag
     6361 gtttgaaagc ttatcgtact aaggatggca gtgttcaact gttccgtcct gatgaaaatg
     6421 ctaaacgtct gcaacgtaca tgtgaccgtc tcttgatgcc acaagttccg acagacatgt
     6481 ttgtagaagc ttgtaaagca gttgtccgtg cgaatgaaga atacgtacca ccatacggaa
     6541 caggtggaac cttatatctt cgccctcttt tgattggtgt cggagatatt atcggggtaa
     6601 aaccggcaga agagtacatt ttcaccatct ttgctatgcc agttggaaat tactttaaag
     6661 gtggtttggt cccaaccaac ttcttgattc aggatgagta cgaccgtgca gcaccaaatg
     6721 gtacaggtgc ggctaaggtt ggtggaaact atgctgcaag tctcttacca ggaaaaatgg
     6781 ccaagtcacg tcatttctca gatgttatct atctggaccc atcaactcat acaaagattg
     6841 aagaagtcgg atcagctaac ttctttggaa ttacagctga taatgaattt gtaacaccat
     6901 tgagtccatc tatcttgcca tctattacca agtattcctt gctttatttg gcagaacatc
     6961 gcttgggatt aactcctatt gagggtgatg ttccaattga taatcttgac cgttttgtag
     7021 aggcaggtgc ctgtggtaca gcagcggtta tttctccaat tggaggtatt caacatggtg
     7081 atgatttcca tgtattctat agtgaaacag aagtaggtcc tgtgacgcgt aaattatata
     7141 atgaattgac gggtattcag tttggcgata ttgaagcgcc agaaggttgg attgtaaaag
     7201 tagattaaaa taaaccaaag gagatttttt atgaaataga aaaagtggct cttaacagca
     7261 ggagtggtcc tgagcacgtc agctatttta gtggcttgtg gaaaaactga taaagaagca
     7321 gatgcaccga caacattttc ttatgtctat gcagtagatc cagcatcatt gggctacagt
     7381 atagcgactc gaacatcgag gacagacgtt attggaaatg ttattgatgg tttgatggaa
     7441 aatgataaat acggcaatgt tgctccttct caaaaagact atgatttgaa cagtacagga
     7501 tgggctccaa gctatcaaga tccagcgtct tacttgaata ttatggatcc aaaatctggt
     7561 tctgacatga aacaccttgg cattacgaaa ggaaaagata aggatgttgt agctaaacct
     7621 ggtttggata aatataagaa attgttagaa gatgctgttt ctgagaccac tgacctagag
     7681 aagagatatg aaaaatatgc caaagctcaa gcttggtcga cagatagttc attattgatg
     7741 ccaacagctt catctggtgg ttttccagtt gtaagtaacg tagtaccatt ctcaaaacca
     7801 tactcacaag ttggtattaa gggggaacca tatatcttta aaggaatgaa attgcaaaaa
     7861 gatattgtta caacaaaaga atataacgag gtttttaaaa aatggcaaaa agaaaaattg
     7921 gaatccaata gcaaatacca aaaagaacta gaaaaataca ttaaataagg aatggtattg
     7981 atcttgataa aatttttaaa atactgtcat tttgaatata aaggagtttg atatggagtg
     8041 gattagatta ataggaatag caatcattgt tgtgggtttt attttaaaat ttgatacaat
     8101 tgcaacagta gtcttagctg gtttggttac agctttagtt tcaggtgttt ctctcgttga
     8161 atttttggag attttgggaa aagaatttag caatcagcga gtgctcacga tttttatggt
     8221 taccttgcct cttgtggggc tgtcagaaac ctttggactc aagcaacgat caatcgattt
     8281 gattcgaaag attaaaggtc tgacagttgg aaacttctat acagtttatt tctttattcg
     8341 agagttagct ggtttctttt caattcgtct aggaggacac cctcagtttg tcagaccttt
     8401 ggttcaacct atgggagaag cagctgcaga gtctcaatta ggtagaaagt taacagaggt
     8461 tgaagatgag acaataaaag cgcgtgcggc tgcgaatgaa aattttggaa atttctttgc
     8521 tcaaaatacg tttgtaggtg ctgggggagt cctcttgata gggggaacat tagatcagtt
     8581 aggctatgaa agcaattatg cagggattgc ttctacatct attattgttg ctgttataac
     8641 acttattgta gtggggattt acaattattt atttgataaa aaattgatat caaaaaagac
     8701 taggggagga gaacaaaaat gacagagttg gcaaagcaac tattagagtt gacctatatt
     8761 gtgattggtt gtcaatttct ccatacagcc tattgtagtt ataaagataa aacaaaccca
     8821 gttcgacttg ggacatctgc attttggact ctattgtcta ttacgtttat aggtggttcc
     8881 tatatgccaa atatgagtat tggtattatt gtaatcctat tatcgctgtt aacattgttt
     8941 aagcaagtcc gtatcggaac cttgccatcc ttagatgaaa tgaaagccaa tattgaatct
     9001 aacaggttga aaaataaaat ttttattcca gttatgctga tggcaatact tgcgttggtc
     9061 ttagcgcaaa tgattccaga atttagcaag atttcgatta gccttgccgc cttgtttgct
     9121 acaatttctg ttcttgtgat taccaatagt caccctaaga gtctgttatc agaaaataat
     9181 cgaatgactc agcaagtttc aacaagtggg attgttcctc aattattagg ggctttgggg
     9241 gctattttta ctgtagcagg tgttggtgat gttatctctc atctgattag cggtattgtt
     9301 ccttcagata gtcgctttat aggagttttg gcttatgttc ttggaatggt tctattcaca
     9361 atgattatgg gaaatgcttt tgcagcattc accgttatta cagcaggtgt tggagttccc
     9421 tttgtatttg ctctgggagc taatccaatt gtggctggtg ctcttgccat gacagcaggt
     9481 tattgtggga ccttattgac cccaatggct gctaatttta acgctctacc agcagcattg
     9541 atggatatga aagatcagaa tggcgttata aaggctcaag caggtgttgc tctagtaatg
     9601 attgttattc acatattctt aatgtacttt ctcgcatttt agtaaaggaa aataaaatga
     9661 aaatattggt tacaggtttt aatccttttg gaggtgaaaa gattaatcca gctttggagg
     9721 ctgtaaaatt attaccatct gagattaatg gggctgaagt tcgctgggta gaaattccaa
     9781 cggtttttta taagtcgtca gaagttttag aggcagaaat attacgatat caaccagatg
     9841 ctgtactttg tattggacaa gcaggcggca ggaccggctt aacacctgaa cgagtggcta
     9901 ttaatcaaga tgatgctcgc atacctgata acgaaggcaa tcaaccaatt gatacaccga
     9961 ttcgtattga tggagcatcg gcctatttta gtagtttacc tatcaaagcg atggtacaag
    10021 ctatcaaaaa acagggactt ccggcagttg tatccaatag tgcaggaacc tttgtttgca
    10081 atcatttgat gtaccaagct ctttatttag tggataaaaa attccctaat atgagagcag
    10141 gtttcatgca tattccatat atgatggaac aagtagtaaa taagccgaat actgcaggaa
    10201 tgagtctatg tgatattgta agaggcatag aggtagctat tgaagctatt gtagactaca
    10261 aagataagga tttgcagtta gtaggcggtg agactcactg ataacctaaa aaggatagtc
    10321 aattatgctt gtttactaac tattaactat gctaaatcaa ttgaggttgt ttacataaaa
    10381 ctctatatca gagaagcctg atatagagtt ttttcttgct agttttagga ttttcttgta
    10441 aaatagaaaa agtgaagaga ggtatgaaat gagcaagaaa gataaaaaaa tcgaaattca
    10501 agtagcggat gccaaagtta atgttggtaa agacagtttt gaaggttata cattgactat
    10561 cggtaaaaaa gttatcggag aaattgccga attagacgga caatttgcca ttataaagaa
    10621 tgggaatgtc gatagttttt ataaaaaatt ggaaaaagct gtggaaattt tgattgaaaa
    10681 ttataattta gcaaaataag tcttgttttt ttgaaatttt catgatataa tagtccatgt
    10741 tgattgtagg agagatagcg aagaggctaa acgcggcgga ctgtaaatcc gctccttcgg
    10801 gttcgggggt tcgaatccct ctctctccat ttcattaatg gggtatagcc aagcggtaag
    10861 gcaagggact ttgactccct catgcgttgg ttcgaatcca gctaccccag ttcttaggta
    10921 ataatcaaga taaaaagcaa aatatcttag ggtattttat ttttataatt gaaagacgtg
    10981 aatgatatga acatgtcctt gcgggtgctt aggaaaaaaa ttataagtat gtcaagttta
    11041 agaaaaactt gattgttgga ggatttttta gatgaacgaa tttgaagatt tgctaaatag
    11101 cgttagtcaa gttgagactg gtgatgttgt tagtgctgaa gtattgacag ttgatgcgac
    11161 tcaagctaac gttgcaatct ctggaactgg tgttgaaggt gtcttgactc ttcgcgaatt
    11221 gacaaacgat cgtgatgcag atatcaatga ctttgttaaa gtaggagaag tattggatgt
    11281 tcttgtactt cgtcaagtag ttggtaaaga tactgataca gttacatacc ttgtatctaa
    11341 aaaacgcctt gaagctcgca aagcatggga caaacttgtt ggtcgcgaag aagaagttgt
    11401 tactgttaaa ggaacgcgtg ccgttaaagg tggactttca gtagaatttg aaggtgttcg
    11461 tggatttatc ccagcttcaa tgttggatac tcgtttcgta cgtaacgctg agcgttttgt
    11521 aggtcaagaa tttgatacta aaatcaaaga agttaacgct aaagaaaacc gcttcatcct
    11581 ttcacgtcgt gaagttgttg aagcagctac tgcagcagct cgcgctgaag tattcggtaa
    11641 attggctgtt ggtgatgttg taactggtaa agttgctcgt atcacaagct tcggcgcttt
    11701 catcgacctt ggtggtgttg acggattggt tcacttgact gaattgtcac atgaacgtaa
    11761 cgtatcacca aaatcagttg taactgttgg tgaagaaatt gaagtgaaaa tccttgatct
    11821 taacgaagaa gaaggacgtg tatcactttc acttaaagca acagtaccag gaccatggga
    11881 tggcgttgag caaaaattgg ctaaaggtga tgtagtagaa ggaacagtta aacgtttgac
    11941 tgacttcggt gcatttgttg aagtattgcc aggtatcgat ggacttgttc acgtatcaca
    12001 aatttcacac aaacggattg aaaatccaaa agaagctctt aaagttggtc aagaagttca
    12061 agttaaagtt cttgaagtta acgcagatgc agaacgcgtg tcactttcta ttaaagctct
    12121 tgaagaacgt ccagcccaag aagaaggaca aaaagaagaa aaacgtgctg ctcgtccacg
    12181 tcgtccaaga cgtcaagaaa agcgtgattt cgaacttcca gaaacacaaa caggattttc
    12241 aatggctgat ttgtttggtg atatcgaact ttaatcaaat tgaaaattca caaaatcctt
    12301 tgtttactaa acaagggatt tttcttttgt ctctgctcct tttttgatat aatagttcta
    12361 tgttaaaatc agaaaaacaa tcacgttatc aaatgttaaa tgaagaattg tccttcctat
    12421 tggaaggcga aaccaatgtt ttggctaatc tttccaacgc cagtgctctt ataaaatcac
    12481 gttttcctaa taccgtattt gcaggctttt atttgttcga tggaaaggaa ttggttttag
    12541 gtcccttcca aggaggtgtt tcctgcatcc gtattgcact aggcaagggt gtttgtggtg
    12601 aggcagctca ctttcaggaa actgttattg ttggagatgt gacgacctat ctcaactata
    12661 tttcttgtga tagtctagct aaaagtgaaa ttgtggtgcc gatgatgaag aatggtcagt
    12721 tacttggagt tctggatctg gattcttcag agattgagga ttacgatgct atggatcgag
    12781 attatttgga acaatttgtc gctattttgc ttgaaaagac aacatgggac tttacgatgt
    12841 ttgaggaaaa atcttaatgt atcaagcact ttatcgaaaa tatagaagtc aaaacttctc
    12901 ccagttagtt ggtcaagaag ttgtggctaa gactcttaaa caagcggtgg agcaagagaa
    12961 aataagtcac gcttatcttt tttctggtcc tcgtggaacg ggaaaaacca gtgttgctaa
    13021 aatctttgcc aaggctatga actgtcccaa tcaagtgggt ggcgaacctt gcaataactg
    13081 ctatatttgt caagcagtga cggacggtag tttagaagat gtcattgaaa tggatgcagc
    13141 ttctaataat ggggtagatg aaattcgcga aattcgtgat aaatctacct atgcgcctag
    13201 ccttgctcgt tataaggttt atatcataga tgaggttcac atgctgtcta caggggcttt
    13261 taatgccctc ctaaagacgc tggaagaacc aacacagaat gtagtcttta ttttggccac
    13321 tactgaatta cacaagattc ctgctactat tctatcccgt gtgcaacgtt ttgagtttaa
    13381 atcaattaag acacaggata ttaaggaaca tattcactat atcttagaaa aagaaaatat
    13441 cagttctgaa ccagaggctg tggaaatcat tgccagacgg gcggaaggtg gaatgcggga
    13501 cgccttgtct attttggatc aagccctgag tttgacacag ggaaatgagc tgacgactgc
    13561 tatctctgaa gaaattactg gcactattag cctatcagcc ttggatgatt atgtggcggc
    13621 cttgtctcaa caggatgttc ccaaagcttt gtcttgcttg aatcttcttt ttgacaatgg
    13681 taagagcatg actcgttttg tgaccgatct tttgcactat ttaagagact tgttaattgt
    13741 tcaaacaggg ggagaaaata ctcatcatag ttcagtcttt gtagaaaatt tggcacttcc
    13801 tcaaaaaaat ctgtttgaaa tgattcgctt agcaacagtg agtttagcag atattaagtc
    13861 tagtttgcag cccaagattt atgctgaaat gatgaccgtc cgtttggcgg aaatcaagcc
    13921 cgaaccagct ctatcaggag cggttgaaaa tgaaattgct acgctgagac aggaagttgc
    13981 ccgtctcaaa caagagcttt ctaatgtagg tgcggttcct aaacaagttg caccagctcc
    14041 tagtcgacca gctacgggca aaacagtcta tcgtgtcgat cgcaataaag tgcaatctat
    14101 cttacaagag gccgtcgaaa atcctgattt agcacgtcaa aatctaattc gtttgcagaa
    14161 tgcctgggga gaggtaattg aaagtctagg tgggccggac aaggctctgc tagttggttc
    14221 tcaaccggtt gctgccaatg aacaccatgc tattcttgct tttgagtcta acttcaatgc
    14281 tggtcaaact atgaaacgag acaatctcaa taccatgttt ggcaatatcc tcagtcaggc
    14341 ggcaggtttt tcacctgaga ttttagctat ttccatggag gaatggaaag aagttcgcgc
    14401 agccttttca gccaaagcca aatcttctca aactgaaaaa gaagtagaag aaagcctgat
    14461 tccagaagga tttgaatttt tggctgataa agtgaaggta gaggaagact aaagaaagat
    14521 ttcgtgatac aataagttta tgaataaaca acaatttatt attatggcgc tgtttacagc
    14581 tgctgagacc tattttttca atgaagcctg gatgactggc cgctatatta tggcagcctt
    14641 ttgggcaatt ttactcttta gaaatttccg agtcagttat gtgatgggca aaatcgttga
    14701 tgtcatcgat cagcatttta ataggaaaga ctagccctca gcttccagac aaaatcaaag
    14761 ccttttaggc ttttttttgt tatactagaa aagtatattt atagaatttt tgctctattt
    14821 ctggggaaat cagacgtttt tctagtaagt actgtaaaag ttttgaaaaa gaaaggaact
    14881 atcatgtcag tattagagat caaagatctt cacgttgaga ttgaaggaaa agaaatttta
    14941 aaaggggtta acctgaccct gaaaacagga gaaattgccg ctatcatggg accaaatggt
    15001 acaggtaaat cgactctttc tgccgctatc atgggaaatc caaactatga agtaactaaa
    15061 ggtgaagttt tgtttgatgg cgtaaacatc cttgagttgg aagtggatga gcgtgcgcgt
    15121 atgggacttt tccttgctat gcaataccca tcagaaatcc ctggaattac caatgctgag
    15181 tttcttcgtg ccgctatgaa tgcgggtaaa gaagatgatg agaagatttc agttcgtgag
    15241 tttattacta ggctagatga aaaaatggaa ttgctcaaca tgaaagaaga aatggcagag
    15301 cgttacctca acgaaggctt ctctggtggt gagaaaaaac gcaatgaaat tcttcaactt
    15361 ttgatgttgg agccaacatt tgctcttttg gacgagattg actcaggtct tgatattgac
    15421 gctcttaaag ttgtgtctaa aggtgtcaat gccatgcgtg gtgaaggttt tggtgctatg
    15481 atcatcactc actaccaacg tcttttgaac tatatcacac ctgatgtggt acacgtgatg
    15541 atggaaggtc gtgttgtcct ttctggtggt ccagaattgg ctgcgcgttt ggaacgtgaa
    15601 ggatacgcaa aattagctga agaacttggc tacgactaca aggaagaatt gtaatttcct
    15661 cgtatctttt aggagaagta aatgactaga gaaaatatta aacttttttc agaaatgcac
    15721 gctgaaccaa gctggttggc tgatctccgt caaaaagctt ttgacaagat tgagactttg
    15781 gaattaccag ttattgagcg tgtcaaattc caccgttgga atctgggtga tggaacgatt
    15841 acagaaaatg agccatcagc aaatgttcca gatttcacag ctttagatca tcacttgaag
    15901 ttggtgcaag taggaactca aactgttttc gaacaaactc cagttgagtt agctgaacag
    15961 ggtgttgtct tcacagactt tcactcagct ttagaagaaa ttccagagct gatcgaagaa
    16021 ttcttcatgt catctgttaa gtatgatgat gacaagttgg cggcttacca cacagcttac
    16081 tttaacagtg gtgctgtact ctatattcca gataacgtag aaatcacaga gccaattgaa
    16141 ggaattttct accaagatag cgatagcaat gtgccgttta acaagcatat tatgattatc
    16201 gctggtaaaa attctaagat taattatctg gagcgtttag agtcacgcgg tgaaggaagt
    16261 gccaaagcaa ctgctaatat cacagtagaa gtgattgcac gttcaggtgc gcaagtcaag
    16321 tttgctgcta tcgaccgtct aggtgaaaac gtcactgcct acattagccg tcgtggtaaa
    16381 ttaggcaacg atgcaagtat tgactgggct atcggtgtca tgaacgaagg aaatgtcgtt
    16441 gctgattttg atagtgactt gattggtaat ggtagctatg ctgacctcaa ggttgtagct
    16501 ctttcaagtg gtcgtcaggt acaagggatt gatactcgtg taactaacta tggctgcaac
    16561 tctatcggaa atatcctaca acatggggtt atccttgaaa aagcaacttt gactttcaat
    16621 ggtatcggcc acatcatcaa gggtgctaag ggagcagatg cccaacaaga gagccgtgtt
    16681 ctcatgcttt cagaccaagc gcgttcagat gctaacccaa ttcttttgat tgatgaaaat
    16741 gatgtcactg caggacacgc agcgtctatc ggacaagttg atccagaaga catgtattac
    16801 ctcatgagtc gtggattgga taaggcaact gcagagcgtt tggttgttcg tggtttcctt
    16861 ggatctgtta tcgtggagat tccagtcaag gaagttcgtg atgaaatgat tgcaactatc
    16921 gaagagaaat tgtcaaaacg ctaaggggaa gcctatgtta gatgtagaag cgattcgcaa
    16981 ggattttcca attttagatc agattgtcaa tgatgaacct ctggtctatc tggacaatgc
    17041 tgcgacgaca caaaaaccac tagtagttct gaaagctatt aacagttact atgagcagga
    17101 caatgccaat gttcaccgtg gtgtccatac cttagcggaa cgagcgacag cttcttatga
    17161 agctgctcgt gaaaccattc gtaagtttat taatgcaggc tctacaaagg aagttctctt
    17221 taccagagga acgacaacca gccttaactg ggtggcacgc tttgctgagg aaattctcac
    17281 tgagggagac caggtcttga tttcagtaat ggaacaccat tctaatatca ttccatggca
    17341 ggaagcttgt cgaaagactg gagcagagct tgtctatgtc tatcttaaag acggtgcctt
    17401 ggatatggag gatttgcgag ctaaattgac tgataaggtt aaatttgttt ccctagctca
    17461 tgcctccaat gttcttggtg tggtcaatcc gatcaaggaa atcactcaat tagcccacca
    17521 agttggggca atcatggtag tggatggtgc tcaatctaca cctcatatga agattgatgt
    17581 ccaggacttg gatctggact ttttcgcctt ttcgggtcac aagatggctg gtccgactgg
    17641 tatcggtgtc ctttacggca aagaaaagta tcttgagcaa atgtctccag tagaatttgg
    17701 cggcgagatg attgattttg tctacgagca atccgctagt tggaaggaat tgccttggaa
    17761 atttgaggct ggaacgccaa atatggcagg agctattgga cttgcgactg cagttgatta
    17821 tctggaaaag attggtatgg atgccgttga agctcatgaa caggaattga ttgcgtacgt
    17881 ctatccaaaa ctgcaggcaa ttgagggatt gaccatttac ggttctcagg atttggctca
    17941 acgttcgggt gttattgcct ttaacctagg tgatctccat cctcacgatc ttgcgacggc
    18001 tctggattat gaaggagtgg ctgttcgtgc tggtcaccat tgtgcgcaac ccttgcttca
    18061 gtatttggaa gtcccagcat cagctcgtgc aagtttttat atctataata ccaaggcaga
    18121 ttgcgacaaa ctagtcgatg ccctacaaaa gacaaaggag tttttcaatg gcactttcta
    18181 aactagatag cctttatatg gcagtggtag cagaccattc gaaaaatcca catcaccaag
    18241 ggaagttaga agacgctgag caaatcagtc tcaacaatcc gacttgtggg gatgtcatca
    18301 acctctctgt caagtttgat gcagaggacc gtttggaaga tattgctttt ctaaattcag
    18361 gatgcacgat ttcaactgct tctgctagta tgatgacaga tgccgtttta ggaaaaacca
    18421 aacaagaaat tttagaactg gcgactattt tttctgaaat ggttcaaggg caaaaagatg
    18481 agcgtcaaga ccaacttgga gacgcggcat tcttgtcagg tgttgccaaa ttccctcaaa
    18541 gaatcaagtg tgcaacccta gcttggaatg cccttaagaa aacaattgaa aatcaagaaa
    18601 aacagtaaga caagtttctt ttgtcttatg aattattaga aatgaagaaa ggatattatg
    18661 gctgaagaaa gagtagaacc aaaaccaatt gaccttggtg aatataaatt tggtttccat
    18721 gacgatgtag agcctgtctt atcgacagga aaaggactca acgaaggtgt tattcgtgaa
    18781 ttatctgctg ctaagggtga gcctgagtgg atgttggagt tccgtttgaa gtcttatgaa
    18841 accttcaaaa aaatgcccat gcaaacttgg ggagcagact tgtcagagat tgactttgat
    18901 gacttaatct actaccaaaa accatctgac aaaccagccc gttcttggga tgatgtacct
    18961 gaaaagatta aagaaacctt tgaacgtatc gggattccag aagctgaacg tgcttattta
    19021 gcaggggctt ctgcccagta cgagtcagaa gtggtttacc acaacatgaa ggaagagttc
    19081 caaaaattag gtattatctt tacagataca gattccgcac tcaaggaata cccagactta
    19141 tttaaacaat actttgcgaa gttggtaccg ccgacagata acaagttggc agccctcaac
    19201 tcagcagtat ggtcgggtgg aacttttatc tacgtgccaa aaggtgtcaa ggtagatatt
    19261 ccacttcaaa cttatttccg tatcaataac gaaaatatag gtcagttcga acgtaccttg
    19321 attatcgttg atgagggagc aagcgtccac tacgtagaag gatgtacagc accaacatat
    19381 tcaagcaata gcttgcacgc tgccattgta gaaatttttg ctttggacgg agcttatatg
    19441 cgttatacaa ctatccaaaa ctggtctgat aacgtctata acttggtaac aaagcgtgct
    19501 aaggctcaaa aggatgccac tgttgagtgg attgatggaa acttgggtgc caaaacgact
    19561 atgaaatatc catctgttta tcttgatgga gaaggagcgc gtggtaccat gctctctatc
    19621 gcctttgcta atgcagggca acaccaagac acgggtgcta agatgattca caatgctcca
    19681 cataccagct cgtctattgt gtctaaatcc atcgctaaag gtggaggaaa ggttgactac
    19741 cgtggacaag tcacctttaa caagaactct aagaaatctg tttcccacat tgaatgtgat
    19801 accattatca tggatgactt gtcagcatca gatactattc catttaatga aattcacaac
    19861 tcgcaagtgg ctttggaaca cgaagccaaa gtatctaaga tttcagaaga gcaattgtat
    19921 tatctcatga gccgtggatt gtcagaatct gaggcaactg aaatgattgt catgggattt
    19981 gtagaaccct ttacaaaaga acttccaatg gaatacgcag ttgagctgaa ccgcttgatt
    20041 agctatgaaa tggagggatc agttggataa aatttgattt tatactcttc gaaaatctct
    20101 tcaaaccacg tcagcatcgc cttaccgtat gtatggttac tgacttcgtc agtttcatct
    20161 acaacctcaa aacagtgttt tgagcaacct gcggctagct tcctagttta ttctttgatt
    20221 ttgagtatta gatttactca aaatcaagga ttttgaagat gaacttgtat caaaaaatcg
    20281 cggtttaaaa tcgcgatttt ttataatttc tcgttaacaa agcggacaaa ctgattccac
    20341 caaactttta agaagaaggc tttttcaatt ttcttgtctg ctaccatttc gaaactaggg
    20401 cgctctgtgg tgatgtaacc ttgaccaatc aagtccttgt cttcataagt caaatggcca
    20461 accactgttc cagcttcaag tggtgctggg attgctttgg aatcaggtgt gaattgaaca
    20521 gattgggaag attgattccc aacacgttcg attagataga tatcctctgg agccactgca
    20581 gttactgtat cttcttttcc atcttgtaca ggggctttgc tatcttgata ggcatcgcct
    20641 tgttgaacga ttttgcgaag tgtaaatgta gaagaaatat aatccattag ggaagatgta
    20701 gctgtaaatc gagcgtaagg attattgtct tgatgatctg catttaaaac aactgtgatg
    20761 actctcatgc ctttttcgac agtagtacca acaaaagact ctccagcctt atctgttgtt
    20821 cctgttttta gcccatcaaa accaccacgg taagcaggca taccttctaa catgtagttg
    20881 gttgaagtga ttgtcatccc agcaaaagta gaagaaggtt ttttggtgat ttctaagact
    20941 tgtgggtatt ttttgatgag gttgcgagca acgatagcga catcataagc actaagctta
    21001 ttttcctcat cttttttaga acctgggtaa atgttatccc ctagagtttc attgttaaga
    21061 cctgtcgtat tgacaacagt ggcatcctga attccccatt ccaagagttt tgcccgcatc
    21121 atatcgatga aatctttttc tgagccagca attttctcag ctagggcaat agcggcgctg
    21181 ttggcactag ataccagagt tgcttcaagc aactcttcga cagtataatt acgggcctcc
    21241 ataggaatat tactggcttc agaatttgtc gtcaattgat aaggataatc agaaatatct
    21301 acaggagtgg agagggtaat acttccgttt tccaaagctt catagaccag ataagcagta
    21361 atcaattttg ttatggaagc aatttcgaca ggttgcgttg catccttctc atagagaatt
    21421 ttaccagtat ttgcctcaac agcaatcgca tgtttagcgg caatggtaaa atcttgagca
    21481 acagcagtag aagcaccccc taaaagagag acagttaaca aagttaaaaa tatttttttc
    21541 atagtagtct tattctatca taaagaaaaa aaatattctt gctttaataa ttcatctgtt
    21601 aagctttttg aaaatatggt aaaataaagt gagggaggta actcatgttt cgtagaaata
    21661 aattattttt ttggaccaca gaaattttac tcttaaccat catcttttac ctatggagac
    21721 agatggggtc tttgattaac ccttttgtta gcgtgcttaa tacaattatg attccatttt
    21781 tattaggggg atttctttat tatttgacaa accctattgt tactttctta aataaagtct
    21841 gtaaactcaa tcgtttgctt ggtattttaa ttaccttgtg tactttggtc tggggaatgg
    21901 tcataggtgt tgtctatctc ttacctattt tgattaatca gttatctagt ttgattatat
    21961 ctagtcaaac tatttatagt cgagtacaag acttaatcat agacttatct aattatcctg
    22021 cgctccagaa tttggatgta gaagctacaa ttcagcagtt aaacttatcc tatgttgata
    22081 ttcttcaaaa tatcctaaat agcgtatcaa atagtgtggg gagcgtcttg tcagctctta
    22141 tcagtactgt tttgattttg attatgactc cagttttttt ggtttatttc ttattagatg
    22201 gacataaatt cttgcccatg cttgaaagaa cgattctaaa gagggatcgc ttgcatattg
    22261 caggcttatt aaagaattta aatgcgacga ttgctcgcta tattagtgga gtttcgattg
    22321 acgcaatcat tataggttgt ttggcttata ttggctatag tattattggt ttaaaatatg
    22381 ctttagtttt tgccattttt tctggtgtag ccaatttaat tccttatgtg gggccaagta
    22441 ttggtttgat tcctatgatc atcgcaaata tattcactga tccccataga ctgctgattg
    22501 cagtgattta tatgcttgtt gttcagcagg tagatggcaa tatcttatat cctcgaatcg
    22561 taggaagtgt tatgaaggtt catccaatca cgattttagt tttacttttg ttgtcaagca
    22621 atatctatgg tgtagttgga atgattgtcg cagtgccaac ctattctatc ttgaaagaaa
    22681 tttctaagtt cttatcccgt ttgtatgaaa atcataaaat aatgaaagaa cgagaaagag
    22741 aattagctaa gtaaaagtca ggagaaccct gatttttctt tactggaagt ggcctttaga
    22801 ttagaagact gaaaataagt taaagtctta aactaatttt cacagctaag aatagtagaa
    22861 gttaatctga taaaaatcga aaaaaccagt ggaattctgt gtcagggtaa gttccactgg
    22921 ttttcatagt ctattaaagt tcgaatgaaa cctatttata gtagattgaa actagaatag
    22981 tacacctcta attctaaaac attgttagaa atcgatttga ctgtcctgat ctattcgttc
    23041 tattcttatt tcattttact atattttggt gcaataagtg aaaagtagtc cgaataatat
    23101 aaggattgat tttatagttt ttaaactcaa atgaattgaa ataaagagag tacgaaaatt
    23161 ctcatctgaa agtattttag aataattctc ttcgtgaatt tcttcaaaac agatagcttc
    23221 atcttaggta tgtgatttct ttttgcattt ttgagttaga taaggtataa tggttttatt
    23281 gtcttttggg gtcgttacgg attcgacagg cattatgagg catattttgc gactcgtgtg
    23341 gcgacgtaaa cgctcagtta aatataactg caaaaaataa cacttcttac gctctagctg
    23401 cctaaaaacc agcaggcgtg acccgatttg gattgctcgt gttcaatgac aggtcttatt
    23461 attagcgaga tacgattaag ccttgtctag cggtttgata agagattgat agactcgcag
    23521 tttctagact tgagttatgt gtcgaggggc tgttaaaata atacataacc tatggttgta
    23581 gacaaatatg ttggcaggtg tttggacgtg ggttcgactc ccaccggctc cattattcct
    23641 ttgcattctt ttgcattcct tggtaaaacg ttgttaaatc aacgtttttt atttttatct
    23701 ttggtattcc tttgcattct tttgctaaaa agggagtcac aaacagaccc tattttaaaa
    23761 aaaggataga aaaaaggata caacatttgt cgcatcctaa aaataatctt ttttccacgg
    23821 aagacatggg attcgaaccc acgcacgcta ttacacgcct accgcgtttc caacacggcc
    23881 tcttaagcct cttgagtaat cttccaatac ttactcaaat agtctaccat aaaggctctt
    23941 atcttgcaat aaaaattcta gaaataagaa aaatgataga ttttgaaaga aaatgataaa
    24001 aaatgcttga cttcaaaaga aagtatgata gaatgaatag tgtaaacgat aacaggaggt
    24061 gattcggtgt taaaaacaga gcggaagcaa ctgattttag aggagttaaa tcaacatcat
    24121 gtagtttctc tagaaaaatt agttagtttg ctagaaacgt cagaatcaac ggttcgaaga
    24181 gacttggatg agttggaagc ggaaaacaag cttcgtcgtg tgcatggtgg agcagaactc
    24241 ccccactcct tacaggaaga agaaaccatt caagaaaaat ctgtcaaaaa ccttcaagaa
    24301 aagaagttgc tggctcagaa agcagcctct ctcattaaag aaaaagatgt catctttatc
    24361 gatgctggaa caacaactgc ttttttgatt catgaattgg tcaataagaa tattacagtt
    24421 gtgaccaact ccattcacca tgccgctcag ttggttgaaa agcagattcc aactgtcatg
    24481 gttggaggaa acgtcaagac ggcgacagat gctagtatcg gtggcgttgc tcttaaccag
    24541 attaaccaat tgcactttga ccgtgccttt atcggaatga atggtgttga cgatggctat
    24601 tatacgactc ctgatatgga ggagggagct gtgaaaagag ctattttgga gaatgccaag
    24661 cagacctacg tcttggtgga ttcgtcaaaa attggacaaa cttgctttgc caaggtagca
    24721 ccactcaaac gcgctatcgt tatcactagt caagggcatg agctcttgca ggttattaag
    24781 gagaaaacgg aggtaataga agtatgattt atacagtcac actcaatcca tccattgact
    24841 atatcgttcg tttggaccaa gtcaaagttg gtagtgtaaa tcgtatggac agtgatgata
    24901 agtttgctgg tgggaaagga atcaatgtca gccgtgtctt gaaacgtttg aatataccaa
    24961 atacagcgac gggatttatc ggtggcttta ctggtaaatt tatcacagat actttagcag
    25021 aggaagaaat cgagacacgt tttgtccagg tggcagaaga tactcgtatc aatgttaaaa
    25081 tcaaagcaga ccaagaaaca gaaatcaacg gaacgggtcc aactgttgaa tcggttcagc
    25141 tagaagaatt gaaagctatt ttatctagtc tgacagcaga agatacagtt gtctttgcag
    25201 gttcaagtgc taaaaatcta ggcaatgtta tctataagga tttgatttcc ttgacgcgcc
    25261 agactggtgc gcaagtggtc tgtgactttg aaggacagac cttaattgat agtttggact
    25321 accagcctct tcttgtaaaa ccaaacaatc atgaacttgg agcgattttt ggggttaaac
    25381 tcgaaagttt agatgaaatt gagaaatacg ctcgtgagtt actggctaag ggtgctcaaa
    25441 atgttattat ctctatggct ggtgatggtg cccttcttgt cacatctgag ggagcttact
    25501 tcgctaaacc aatcaaagga acagtcaaaa attcagttgg agctggtgat tctatggttg
    25561 ctggattcac aggtgaattt gtcaaatcaa aagacgtagt agaagccttc aaatggggag
    25621 tggcttgcgg aacggcaact accttctcag atgacttggc aacggcggaa tttattaaag
    25681 aaacatatgg aaaagttgag gtagaaaaac gatgaaaatt caagacctat tgagaaaaga
    25741 tgtcatgttg ctagatttgc aggcaactga aaaaacagct gtcatcgacg agatgattaa
    25801 aaatttgaca gaccacggtt atgtaacaga ttttgaaaca tttaaagaag gaattttggc
    25861 gcgtgaagct tcgacttcta ctggtttggg tgatggaatc gcaatgcctc acagcaaaaa
    25921 cgctgctgtc aaagaagcga cagttctatt tgctaagtca aataagggtg ttgactacga
    25981 gagcttggat ggacaagcaa ctgacctctt cttcatgatt gcagctccag aaggtgccaa
    26041 tgatactcac ttggcagcct tggcagaatt gtctcaatac ttgatgaaag acggttttgc
    26101 agacaaactt cgtcaagcaa catctgcaga ccaagttatc gaactttttg accaagcttc
    26161 agaaaaaact gaggaacttg ttcaagcacc tgctaatgac tctggtgact ttatcgtagc
    26221 tgttacagct tgtacaacag gtattgccca cacttacatg gcccaagaag cccttcaaaa
    26281 agtagctgct gaaatggggg ttggtatcaa ggtcgaaacc aacggtgcta gcggtgttgg
    26341 aaatcaacta actgcagaag atatccgtaa ggctaaagct attatcattg cagcagacaa
    26401 ggccgttgaa atggatcgat ttgatggaaa accattgatc aatcgtccag ttgctgacgg
    26461 tatccgtaag acagaagagc taattaactt ggctctttca ggagatactg aagtctaccg
    26521 tgccgctaat ggtgccaaag ctgcaacagc ctctaacgaa aaacaaagcc ttggtggtgc
    26581 cttgtacaaa cacttgatga gtggtgtatc tcaaatgtta ccattcgtta tcggtggtgg
    26641 tatcatgatt gcccttgcct tcttgattga cggtgctttg ggtgttccaa atgaaaacct
    26701 tggcaatctt ggttcttacc atgagttagc ttctatgttc atgaaaattg gtggagctgc
    26761 ctttggtttg atgcttccag tctttgcggg ttatgttgcc tactctattg ctgaaaaacc
    26821 gggtttggta gcaggtttcg tggctggtgc tattgccaaa gaaggttttg cctttggtaa
    26881 aattccttat gccgcaggtg gtgaagcaac ttcaactctt gcaggtgtct catctggttt
    26941 cctaggtgcc cttgttggtg gatttatcgc aggtgccttg gttcttgcca tcaagaaata
    27001 cgttaaagtt cctcgttcac tcgaaggtgc taaatcaatc cttctattgc cacttcttgg
    27061 aacaatcttg acaggatttg ttatgctagc tgtgaatatc ccaatggctg caatcaacac
    27121 tgctatgaat gacttcctag gcggtcttgg aggaggttca gctgtccttc ttggtatcgt
    27181 ccttggtgga atgatggctg ttgacatggg tggaccagtt aataaagcag cttatgtctt
    27241 tggtacaggt acgcttgcag caactgtttc ttcaggtggt tctgtagcca tggcagcagt
    27301 tatggctgga ggaatggtgc caccacttgc aatctttgtc gcaactcttc ttttcaaaga
    27361 taaatttact aaggaagaac gtaactctgg tttgacaaac atcatcatgg gcttgtcatt
    27421 tatcactgag ggagcgattc catttggtgc cgctgaccca gctcgtgcga ttccaagctt
    27481 catccttggt tcagcagtag caggtggact cgttggtctt actggtatca aactcatggc
    27541 gccacacgga ggaatcttcg ttatcgccct tacttcaaat gctctccttt acctcgtttc
    27601 tgtcttggta ggagcaatcg taagtggtgt ggtttatggt tacctacgca aaccacaagc
    27661 ataaaaaata gaaaaatgaa aagattggac cgtttggtgc agtctttttc tcttcccgaa
    27721 atgcctgtga aatatggtat aatagaagaa tggcaaacaa gaatacaagt acaacaagac
    27781 ggagaccgtc taaagcagaa ctggaaagaa aagaagcgat tcaacgaatg ttgatttcgt
    27841 taggaattgc gattttattg attttcgcag ccttcaaatt aggggctgca ggtataaccc
    27901 tttataattt aattcgcttg ctagtgggta gcctagctta tctggcgata ttcggcctat
    27961 taatctatct cttctttttc aagtggatac gaaaacagga aggactctta tctggctttt
    28021 tcaccatatt tgctggctta ctcttgattt ttgaggccta cttggtttgg aaatatggtt
    28081 tggacaagtc cgttctaaaa gggaccatgg ctcaggttgt gacagatctg actggttttc
    28141 gaacgactag ctttgctgga gggggcttga tcggggtcgc tctttatatt ccaacagcct
    28201 ttctcttttc aaatatcgga acttacttta ttggttctat cttgatttta gtgggttctc
    28261 tcctagtcag cccttggtct gtttacgata ttgctgaatt tttcagtaga ggctttgcca
    28321 aatggtggga agggcacgag cgtcgaaaag aggaacgctt tgtcaaacaa gaagaaaaag
    28381 ctcgccaaaa ggctgagaaa gaggctagat tagaacaaga agagactgaa aaagccttac
    28441 tcgatttgcc tcctgttgat atggaaacgg gtgaaattct gacagaggaa gctgttcaaa
    28501 atcttccacc tattccagaa gaaaagtggg tggaaccaga aatcatcctg cctcaagctg
    28561 aacttaaatt ccctgaacag gaagatgact cagatgacga agatgttcag gtcgattttt
    28621 cagccaaaga agcccttgaa tacaaacttc caagcttaca actctttgca ccagataaac
    28681 caaaagatca gtctaaagag aagaaaattg tcagagaaaa tatcaaaatc ttagaagcaa
    28741 cctttgctag ctttggtatt aaggtaacag ttgaacgggc cgaaattggg ccatcagtga
    28801 ccaagtatga agtcaagccg gctgttggtg taagggtcaa ccgcatttcc aatctatcag
    28861 atgacctcgc tctagccttg gctgccaaag atgtccggat tgaagcacca atccctggga
    28921 aatccctaat cggaattgaa gtgcccaact ccgatattgc cactgtatct ttccgagaac
    28981 tatgggaaca atcgcaaacg aaagcagaaa atttcttgga aattccttta gggaaggctg
    29041 ttaatggaac cgcaagagct tttgaccttt ctaaaatgcc ccacttgcta gttgcaggtt
    29101 caacgggttc agggaagtca gtagcagtta acggcattat tgctagcatt ctcatgaagg
    29161 cgagaccaga tcaagttaaa tttatgatgg tcgatcccaa gatggttgag ttatctgttt
    29221 acaatgatat tccccacctc ttgattccag tcgtgaccaa tccacgcaaa gccagcaagg
    29281 ctctgcaaaa ggttgtggat gaaatggaaa accgttatga actctttgcc aaggtgggag
    29341 ttcggaatat tgcaggtttt aatgccaagg tagaagagtt caattcccag tctgagtaca
    29401 agcaaattcc gctaccattc attgtcgtga ttgtggatga gttggctgac ctcatgatgg
    29461 tggccagcaa ggaagtggaa gatgctatca tccgtcttgg gcagaaggcg cgtgctgcag
    29521 gtatccacat gattcttgca actcagcgtc catctgttga tgtcatctct ggtttgatta
    29581 aggccaatgt tccatctcgt gtagcatttg cggtttcatc aggaacagac tcccgtacga
    29641 ttttggatga aaatggagca gaaaaacttc ttggtcgagg agacatgctc tttaaaccga
    29701 ttgatgaaaa tcatccagtt cgtctccaag gctcctttat ctcggatgac gatgttgagc
    29761 gcattgtgaa cttcatcaag actcaggcag atgcagacta cgatgagagt tttgatccag
    29821 gtgaggtttc tgaaaatgaa ggagaatttt cggatggaga tgctggtggt gatccgcttt
    29881 ttgaagaagc taagtctttg gttatcgaaa cacagaaagc cagtgcgtct atgattcagc
    29941 gtcgtttatc agttggattt aaccgtgcga cccgtctcat ggaagaactg gagatagcag
    30001 gtgtcatcgg tccagctgaa ggtaccaaac ctcgaaaagt gttacaacaa taaaaaaata
    30061 gcttctttcc aagtttggag ggaagctatt ttagtggcta ttgattgctt ttattttctg
    30121 aagttggcgc attggactgt ttttcgtttt cagtagcagg tttacttgaa gcaggagtag
    30181 aagagtcctg agttgctgtt ttctgatctt cttttttctc ttccttgacg ctagattttg
    30241 gtgtttcctc ttgctgtgtt ttttcttgac tagtgttagt ctctttagtt ggactggtgt
    30301 tttccttagg ggattccttt tggatttctt tgacaatggt tgtcgtctgg cttgtcgtag
    30361 gttctttttt aatatttttg ttattatcca aggcgttcat aatcgtgata cttgcggtaa
    30421 tcaagccaag gatactagcg attgtagcaa cggttttttg aaagactgta aagccttttt
    30481 tgatgtgttc tgtttttggt tttgaagttc tacgatagtt agacatacat tctctccttt
    30541 gattatgatt tattatactc tgtttcttta aaaaaatctt aaaaaaagag aaatttccct
    30601 ttcttgtcgc aagctccgtt tcatgataca atagaggaag tgattttaga aagcgtgaga
    30661 aacatgattt actttgataa ttcagcgacg accaagcctt atcctgaagc ccttgaaacc
    30721 tatatgcagg tcgcttcaaa aattttagga aacccatcta gtctccatcg tttgggagac
    30781 caagcaacac gaatcttaga tgcttctcgc caacagattg cagatttaat cggtaagaaa
    30841 agcgatgaaa tcttctttac ctcgggtgga acagaagggg ataactggct tatcaagggt
    30901 gtggcctttg aaaaagctca gtttggcaag cacatcattg tttcagccat tgaacatcca
    30961 gcagtcaaag agtcagccct ctggttgaaa agtcaaggat ttgaagtgga ttttgctcca
    31021 gttgataaga aaggcttggt cgatgttgag gcgttagcag gtttgatacg gcatgataca
    31081 atcctcgttt ccatcatggc tgtgaacaat gaaatcggct ctatccaacc tattgaggct
    31141 atttcagaat tcttggcaga caagccgact atttccttcc acgttgatgc ggttcaggcg
    31201 cttgccaaaa ttccgactga aaagtatctg acagaacggg tggattgcgc gactttctct
    31261 agtcacaagt tccacggggt tcgaggtgtt ggctttgtct atatcaaatc tggcaagaag
    31321 attacacctc ttcttacagg tggtggccag gagcgagatt atcgttcgac aactgaaaat
    31381 gtggcaggga ttgcagcgac agccaaggcc ctccgtttgt ctatggaaaa gctagatatc
    31441 tttaggagca agactgggca gatgaaggca gtgattcgcc aagctcttct gaactatccg
    31501 gatatttttg tcttttcaga tgaggaaaac tttgcacctc atattctgac ttttggaatc
    31561 aaaggtgttc gaggtgaagt catcgttcac gcctttgaag actatgatat tttcatctca
    31621 acaacctcag cttgttcatc taaggcagga aaaccagccg gtaccttgat tgccatggga
    31681 gtggacaaag ataaggccaa gtcagctgtg cgtcttagcc tagacttgga aaatgatatg
    31741 agtcaggtcg agcagttttt gaccaagtta aaattgattt acaatcaaac tagaaaagta
    31801 agataggagc attcatgcag tattcagaaa ttatgattcg ctacggagag ttgtcaacca
    31861 agggtaaaaa ccgtatgcgt ttcatcaata aacttcgtaa taatatttcg gacgttttgt
    31921 ctatctatac ccaagttaag gtaacagcag atcgcgaccg tgcccacgct tacctcaatg
    31981 gagctgatta cacagcagtt gcagaatctc tcaaacaagt ttttggaatt caaaactttt
    32041 ctcctgttta taaggttgaa aaatctgtag aagttttgaa gtcttctgtc caagagatta
    32101 tgcgggacat ctacaaggaa ggtatgacct ttaagatttc tagcaagcgt agcgaccaca
    32161 actttgaact tgatagtcgt gaactcaacc aaacacttgg aggggctgta ttcgaagcca
    32221 ttccaaatgt gcaagttcaa atgaaaagtc ctgacatcaa tcttcaggtg gagattcgtg
    32281 aagaagcagc ctatctttct tatgaaacca ttcgtggggc tggtggtttg ccagttggaa
    32341 cttcaggtaa agggatgctc atgttgtcag gagggattga ctcacctgta gcaggttatc
    32401 ttgctcttaa gcgtggggtg gatatcgagg cagttcactt tgctagtcca ccatatacta
    32461 gtcctggtgc cctcaagaaa gcgcaggact tgacccgtaa attgaccaag tttggcggaa
    32521 atatccagtt tatagaggtg cctttcacag agattcaaga ggaaatcaaa gccaaagcgc
    32581 cagaagctta tttgatgact ctaactcgtc gctttatgat gcggattact gaccgtattc
    32641 gtgaggtacg aaatggtttg gttatcatca atggggaaag tctaggtcaa gtagccagcc
    32701 aaacccttga aagtatgaag gctatcaatg ctgttaccaa cactcccatc attcgtcctg
    32761 tggttaccat ggacaagttg gaaatcattg acatcgccca ggaaatcgat acctttgaca
    32821 tttcaatcca accgtttgaa gactgttgta ccatttttgc accagatcgt ccaaaaacaa
    32881 atcctaaaat taagaatgcg gagcagtacg aagcgcgtat ggatgttgaa ggcttggttg
    32941 agcgagcagt ggctggaatc atgattactg aaatcacacc tcaagccgaa aaagatgaag
    33001 ttgatgactt gattgacaat ctgctctaat tcagaaaatc caaaagaata gcgaaaatca
    33061 gtaaaaaaag ttagtttttt ctctaaaaac aggtaaaaaa ctaacttttt ttatttttat
    33121 gatataatga tataaaattt tgaatataga gagttttctg acaatgaatc aatcctactt
    33181 ttatctaaaa atgaaagaac acaaactcaa ggttccttat acaggtaagg agcgccgtgt
    33241 acgtattctt cttcctaaag attatgagaa agatacagac cgttcctatc ctgttgtata
    33301 ctttcatgac gggcaaaatg tttttaatag caaagagtct ttcattggac attcatggaa
    33361 gattatccca gctatcaaac gaaatccgga tatcagtcgc atgattgtcg ttgctattga
    33421 caatgatggt atggggcgga tgaatgagta tgcggcttgg aagttccaag aatctcctat
    33481 cccagggcag cagtttggtg gtaagggtgt ggagtatgct gagtttgtca tggaggtggt
    33541 caagcctttt atcgatgaga cctatcgtac aaaagcagac tgccagcata cggctatgat
    33601 tggttcctca ctaggaggca atattaccca gtttatcggt ttggaatacc aagaccaaat
    33661 tggttgcttg ggcgtttttt catctgcaaa ctggctccac caagaagcct ttaaccgcta
    33721 tttcgagtgc cagaaactat cgcctgacca gcgcatcttc atctatgtag gaacagaaga
    33781 agcagatgat acagacaaga ccttgatgga tggcaatatc aaacaagcct atatcgactc
    33841 gtcgctttgc tattaccatg atttgatagc agggggagta catctggata atcttgtgct
    33901 aaaagttcag tctggtgcca tccatagtga aatcccttgg tcagaaaatc taccagattg
    33961 tctgagattt tttgcagaaa aatggtaagt taagaaagga aaaaacgaaa tgcatattga
    34021 acatcttagc cactggagtg gtcatcttaa ccgtgaaatg taccttaacc gttatggaca
    34081 tggtgggatt ccagttgtgg tctttgcttc atcaggtggt agtcacaacg aatactatga
    34141 ttttggcatg attgatgcct gtgcttcctt tatcgaggaa ggccttgtcc agttctttac
    34201 cctatctagt ttggatagtg agagctggtt ggctacttgg aaaaatgctc atgaccaagc
    34261 ggaaatgcac cgtgcctacg aacgttatgt gattgaggag gccattcttt tatcaagcac
    34321 aagacaggtt ggtttgatgg catgatgacg acaggttgct ctatgggagc ctatcatgca
    34381 ctcaatttct tcctccagca tccagatgtc tttaccaaag tgattgctct cagtggtgtt
    34441 tacgacgcac gtttctttgt cggtgattac tacaacgatg atgctattta ccaaaactcg
    34501 ccagtagatt atatttggaa ccaaaacgac ggctggttta ttgaccgtta ccgtcaggca
    34561 gagattgtgc tgtgtacggg gcttggagcc tgggaacaag atggtttgcc atccttttac
    34621 aagctcaaag aagcctttga caagaaacaa attccagcct ggtttgctga atggggacat
    34681 gatgtcgccc atgactggga atggtggcgt aaacaaatgc cttatttcct cggtaatctc
    34741 tatttataaa aggagttacc tatgaattac cttgttattt ctccctacta tccacaaaac
    34801 tttcaacagt ttaccatcga actagctaat aaaggcatca cagtcttggg aattggtcaa
    34861 gagtcttacg agcaattgga tgagcccttg cgcaatagct tgaccgagta ttttcgtgtt
    34921 gataatcttg agaacataga tgaagtcaaa cgtgcagttg cttttctctt ttataaacat
    34981 ggtccaattg gccgcatcga gtctcacaat gaatactggc ttgagctaga cgcaacactc
    35041 agagaacaat tcaatgtttt tggtgccaaa ccagaggatc tcaaaaagac gaaatataag
    35101 tctgaaatga agaaactttt caaaaaagca ggtgttcctg tggtacctgg agctgttatc
    35161 aagacggaag cagatgttga tcaagcagtg aaagaaatcg gtcttccaat gattgccaaa
    35221 cctgataatg gagtgggagc agccgcaacc tttaaacttg agacagaaga cgatatcaat
    35281 cacttcaagc aagaatggga ccattcaacc ctttatttct ttgaaaaatt tgtcacttcc
    35341 agcgaaatct gtacctttga cgggctcgtg gacaaggatg gaaagattgt cttctcaaca
    35401 acctttgact acgcctatac accgcttgac ctcatgattt ataagatgga caattcttat
    35461 tatgtgctca aggatatgga tcctaaactg cgcaagtatg gggaagcaat tgtcaaagaa
    35521 tttggtatga aagaacggtt tttccatatt gagttcttcc gtgaggggga cgattatatt
    35581 accatcgagt acaataaccg ccctgcaggt ggttttacca ttgatgttta taactttgct
    35641 cattccttgg acctttatcg tggctatgca gctattgtcg caggagagga gttcccggcg
    35701 tcagactttg aaactcagta ttgtttggct acttctcgcc gtgcaaatgc tcactatgtt
    35761 tattcagaag aggatttgct tgccaaatat agccagcagt tcaaggttaa aaaagtcatg
    35821 ccagctgcct tcgcggaact tcaaggagat tacctgtata tgctgaccac tccgagtcga
    35881 caagaaatgg agcagatgat tgcagatttc ggacaacgtc aagaataaga actatcggat
    35941 taaggaaatt aactccctta atccttttgt tttgtctgat aaaaaataag agcatcccaa
    36001 caaggtagct atcataaaac ttgttcgata actatttgaa gcaggattag gtggtcagaa
    36061 attaaatttt aatatttcaa ttgagtcata gtattgtgtt tgcgtatcct taaatcagct
    36121 aaaaggatcc atgacgacac ctatacgata tagttttcaa gataccaaac aagtctatta
    36181 atattcaatg aaaatcaaag agcaaactag gaagctagcc gcaggtttct caaaacactg
    36241 ttttgaggtt gtggatagaa ctgacagagt cagtatcata tacctacggc aaggtgaagc
    36301 tgacgtggtt tgaagagatt ttcgaagagt ataaaatatt caggtgacgc atagatatag
    36361 ttaattgaag ctttgtttga aatctgataa aataatgata ttactaagtt ttaaaaacta
    36421 aagaaaaggg aagatatgat tacaggcgaa ttaaaaaata aaatcgatca gctgtgggaa
    36481 attctttgga cagaaggaaa cgcaaatcct ttaacaaata ttgaacagtt gacttatctc
    36541 ttatttatga aagatttgga tagtgtcgag cttggacgtg aaagtgatgc tgaatttcta
    36601 gggattcctt atgagggagt ttttccaaaa gataaacctg aataccgttg gtcaactttt
    36661 aaaaatatag gagatgctca ggaagtttat cgtttaatga ctcaggagat ttttccgttt
    36721 attaaaaatc tcaaggggga tacagatgat acagcctttt cacgatatat gcgagaagct
    36781 atttttcaaa taaataaacc tgctacgctt caaaaggcaa tttctatctt agatgttttt
    36841 ccaactaggg gattagatgt agattttgat aatgacaaac aaagtattac tgatatcgga
    36901 gatatctatg aatatctgtt atcaaaattg tcgaccgcag gtaaaaatgg acagttccgt
    36961 acacctcgtc acatcatcga tatgatggtt gagttgatgc aaccgactat caaagatatc
    37021 atctcagatc ccgctatggg ttctgctggc ttcttagtat ctgctagccg ttacttaaag
    37081 cgtaagaaag atgaatggga aaccaataca gataatatca atcattttca taatcagatg
    37141 tttcatggaa atgatacgga tacgactatg ttgagacttg gggcgatgaa catgatgcta
    37201 catggagtag aaaatccaca aatcagttac cttgactcgc tgtctcaaga taatgaagaa
    37261 gccgataaat atactttggt tttagcaaat cctcctttta agggctcact tgactacaat
    37321 tcaacctcta atgaccttct tgcaaccgta aaaaccaaaa aaacagaatt actctttctt
    37381 tctcttttct tgcgaacttt aaaaccaggt ggacgagcag cagttatcgt acctgatggt
    37441 gtcctttttg gttcgtctaa agctcataaa ggaattcgtc aggaaattgt agagaatcat
    37501 aagcttgatg ctgtaatctc aatgcctagt ggtgtgttca agccttatgc tggagtttca
    37561 actgccattc tcatctttac aaaaactggt aatggtggta ctgacaaagt ctggttttac
    37621 gatatgaaag cggatggttt aagtttggat gataagcgac aaccgattag cgacaatgat
    37681 attccagata ttatcgaacg ctttcatcat cttgaaaaag aagcagaacg tcagagaacg
    37741 gatcaatctt tctttgttcc agttgctgag ataaaggaaa atgattatga tttgtctatc
    37801 aataaatata aagagattga gtatgaaaaa gttgagtatg aaccaacaga ggtcatctta
    37861 aagaaaatca atgatttaga aaaagaaatt caagctggct tggctgaatt agaaaaatta
    37921 ctcaagtaga gaggtggctg tatgaaaaaa gtgaagttgg gggaagtctt atctctaaaa
    37981 aaaggcaaga aagccactgt acttgctgaa caaacaactc taagccaacg ttatattcaa
    38041 atagatgatt taagaaataa taataattta aaattcactg aaagtttaaa tatgactgaa
    38101 gcactcccag atgatattct gatagcatgg gatggagcta atgcaggaac agttggttat
    38161 ggattatcgg gagctgttgg tagtacaatt acggtcttaa aaaagaatga gcgatacaaa
    38221 gaaaaaatta tatcagatta cttgggagtc tttttggaaa gtaaatcgca gtatttacga
    38281 gaacattcaa caggtgcaac aattcctcat ttaaacaaga atatattact tgatttacaa
    38341 ttagaattgc taggtatcga agaacaagag aacattatct gtattcttaa tacgattaaa
    38401 aggcttatta ctaaaagaaa attgcagtta gatgaactaa acttgctcgt caaatcccga
    38461 tttaacgaga tgtttgggga tgttattcta aatgaaaaag aatggaaagt tagcaaatgg
    38521 aacgagattc taacaataag aaatggtaaa aatcaaaaac aggttgaaga tgctgatggg
    38581 aaatttccta tttatggaag tgggggaatt atgggatatg ctaaagattg gatagtgaag
    38641 aaaaattcag ttattattgg acgtaaagga aatataaata aacctatttt agttagagaa
    38701 aatttttgga atgtagatac agcatttgga ttagagcctg ttttagaaaa aataaactca
    38761 gaatatttat tctatttttg tcaattatac aattttgaga agttaaataa ggctgtaaca
    38821 atacctagtt taactaaatc agatttatta aatatttcca tccccctccc cccactagcc
    38881 ctccaaaatg agttcgcaga ctttgtagcc ctggtcgaca aatcacaatt tgcttgtgag
    38941 atagctataa aagtgtggag aaatagcttg aaatttagta taatatagct aaactatttg
    39001 tttaaagtga gaaaaaaatg ggaaatttta gctttctttt aaaaaatgac gaatatgaat
    39061 ctttttcaaa accttgcatt gaagctgaga atatgattgc tacatcaact gtggctactg
    39121 cctttatggc gcgtcgtgct ttagagcagg ctgtccattg gatatatagt cacgattcat
    39181 atttagaagc tccctatcgt gctactctat cttctttagt atgggatgat gattttaggg
    39241 atatcgtaga ttctgaactc cacaagcaga tagttctgtt gattcggtgg ggaaaccatg
    39301 ctgctcatgg tggtgaaatt aaggaacgag aagcgatttt agctttgcat catttgtatc
    39361 agtttgttaa ttttatcgat tattgttaca gcaatgagtt tgtggagcgt tattttgatg
    39421 agaagtgctt accactttca gcaaacatca aataccgaga aactccacaa tctatgataa
    39481 agttacaaga cagtttacca gaactgcctg attttcatga acagatggct gctcagtccg
    39541 tagaagttca agagacttat actgaaaaac gtgagactgc agcgcaacgg caagatgtgc
    39601 ctttccatat tgatcaatta tctgaggcag agacaagaaa gctctttatt gatatcgatc
    39661 tccgtttagc aggatggata tttgaagaaa actgtcgtgt tgagatagcc gttgatggtc
    39721 tcaagcacgg ttcaggaatt ggttactgtg actatgtact ttatggtaaa aatgggaaaa
    39781 ttttagcgat tgtggaggct aaaaaagcct ctgtcaatcc agaagtaggg gaagtacagg
    39841 tcaaagaata tgctgaagct ttggagaaac atatcggcta tcagccaatt tgctttatta
    39901 caaatgggtt gaagcactat atacttgatg gtccgaaccg ccgccagatt gcaggctttt
    39961 actctcaaga agaattgcaa ttagtgatgg atagacgtca tcttcaaaaa ccgcttgagg
    40021 atatttctag taaaattagg gacgatattt ccgggcgtca ctaccaaaaa catgccattg
    40081 caagcgtttg tgaagctttc tctgatcatc gtagacaggc acttttggtt atggcaactg
    40141 gggcggggaa aactcgtaca gcagtttctc tagttgatat cttatcacgt cataactggg
    40201 taaaaaacgt tctcttctta gccgatagaa cttccttggt taagcaagca tatgattcgt
    40261 ttagaaaatt actcccagat ctttccgttt gtaacttctt agaagataaa gaaggagctc
    40321 aatcaagtcg aatggtcttt tcaacttatc cgaccatgat tggagcgatt agtggtcaag
    40381 aagaagtaaa tcaacgccct tttactgttg ggcattttga ccttatcata attgacgaat
    40441 ctcaccgttc tatttatcag aaatacaagt ccatttttga ttattttgat gcaaggattg
    40501 taggcttaac agctactccg cgtcaagatt tagataaaaa cacctatgga ttctttaatt
    40561 tggagaatgg ggttccaaca tatgcatatg atttggaaga ggctgttaaa gacggatatt
    40621 tagtagccta tcattctatc gaaaccaaac tgaaactacc tacggatggt ctacattatg
    40681 atgatttgtc cgaagaagaa aaggaacatt ttgatagcaa atttgaagac gatagctgtg
    40741 aaaaagatat tgatgggagt gtgtttaatt cctttatttt caataaaagt acagtagaaa
    40801 ttgttttaaa tgaactcatg acaagaggaa ttcagacagc ctcgggtgat gaaattggta
    40861 aaactattat ttttgctaaa aatcatgacc atgcggaata tatcagaggt atttttaaca
    40921 accgctatcc tgaaaaaggg agcgactatg ctcaggtgat tgattatagt attaagcatt
    40981 atcagacctt gattgatgat tttaaaatta aggagaagta tcctcaaatt gcgatttctg
    41041 tcgatatgtt agatacaggt attgatgtac cagaggttgt taatttagtc ttcttcaaga
    41101 aagtacgctc taaaactaag ttttggcaga tgattggtcg aggaacccgt ctatgtaaag
    41161 atttatttgg acctgagcag gataaggaaa acttcttggt atttgattat ggggacaatt
    41221 ttgattattt tcgtgcagat ccaagagatg gagagggtcg tcacattgtt tcgctgactc
    41281 agcgtttatt taatatcaaa gtggacttga ttcgagaact tcagggactc caataccaag
    41341 aagatcagtt tgcgagagca taccgtcagc agcttgtctc ggaacttcaa ggtcgtatag
    41401 agagcttaaa tgagttggac ttcagggttc gtatggtttt agatacagtt tatagctata
    41461 ggaaattgga aagttggcag aatctaactg ctgttacaag tgaaaccatt caaaaaaatc
    41521 tctctccgct tttatttgat gaagataaag aagatgagat ggcgaggaga tttgatttgt
    41581 ggttgcttca tattcagttg gggcaactga cagctaaatc ttccactgtt catatttccc
    41641 aagtgatgaa gacggctaga gctctttctg ctattggcaa tatcccgcag gtttttgagc
    41701 aggctgaaat ta
//
LOCUS       DAVBEM010000013        39690 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVBEM010000013 DAVBEM010000000
VERSION     DAVBEM010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39690
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.013"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            <1..151
                     /locus_tag="VQ548_000710"
     CDS             <1..151
                     /locus_tag="VQ548_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="choline-binding protein D"
                     /protein_id="HET2653602.1"
                     /translation="WYYLEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYKVNA
                     NGEWV"
     gene            552..1673
                     /gene="mnmA"
                     /locus_tag="VQ548_000711"
     CDS             552..1673
                     /gene="mnmA"
                     /locus_tag="VQ548_000711"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HET2653603.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1814..2269
                     /locus_tag="VQ548_000712"
     CDS             1814..2269
                     /locus_tag="VQ548_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2653604.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELDVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLQNIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2279..4192
                     /gene="mnmG"
                     /locus_tag="VQ548_000713"
     CDS             2279..4192
                     /gene="mnmG"
                     /locus_tag="VQ548_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HET2653605.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(4616..6295)
                     /locus_tag="VQ548_000714"
     CDS             complement(4616..6295)
                     /locus_tag="VQ548_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET2653606.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6297..6530)
                     /locus_tag="VQ548_000715"
     CDS             complement(6297..6530)
                     /locus_tag="VQ548_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HET2653607.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            6912..7133
                     /locus_tag="VQ548_000716"
     CDS             6912..7133
                     /locus_tag="VQ548_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653608.1"
                     /translation="MTNQVLEENYLCDSLLAFSPPRDLCRLVCILLWIKCLDALLMLG
                     FFVWGCRDSRFTTRKFHPIYQDEVVFAFF"
     gene            complement(7346..7498)
                     /gene="cibB"
                     /locus_tag="VQ548_000717"
     CDS             complement(7346..7498)
                     /gene="cibB"
                     /locus_tag="VQ548_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HET2653609.1"
                     /translation="MMKDLNNCREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7500..7685)
                     /gene="cibA"
                     /locus_tag="VQ548_000718"
     CDS             complement(7500..7685)
                     /gene="cibA"
                     /locus_tag="VQ548_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HET2653610.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            7863..8546
                     /gene="tsaB"
                     /locus_tag="VQ548_000719"
     CDS             7863..8546
                     /gene="tsaB"
                     /locus_tag="VQ548_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HET2653611.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMESLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLTHTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMPEAHLSFEEVLEKVKGASQVTFVGEVGPF
                     VEQIQEHLPRTNYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8543..8980
                     /gene="rimI"
                     /locus_tag="VQ548_000720"
     CDS             8543..8980
                     /gene="rimI"
                     /locus_tag="VQ548_000720"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HET2653612.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            8970..9980
                     /gene="tsaD"
                     /locus_tag="VQ548_000721"
     CDS             8970..9980
                     /gene="tsaD"
                     /locus_tag="VQ548_000721"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HET2653613.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(10026..11326)
                     /locus_tag="VQ548_000722"
                     /pseudo
     CDS             complement(10026..11326)
                     /locus_tag="VQ548_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11602..11953)
                     /locus_tag="VQ548_000723"
                     /pseudo
     CDS             complement(11602..11953)
                     /locus_tag="VQ548_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12060..12352)
                     /locus_tag="VQ548_000724"
                     /pseudo
     CDS             complement(12060..12352)
                     /locus_tag="VQ548_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            12595..13801
                     /locus_tag="VQ548_000725"
                     /pseudo
     CDS             12595..13801
                     /locus_tag="VQ548_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            13794..14442
                     /locus_tag="VQ548_000726"
                     /pseudo
     CDS             13794..14442
                     /locus_tag="VQ548_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            14452..16068
                     /locus_tag="VQ548_000727"
     CDS             14452..16068
                     /locus_tag="VQ548_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2653614.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLSGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            16088..16932
                     /locus_tag="VQ548_000728"
                     /pseudo
     CDS             16088..16932
                     /locus_tag="VQ548_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813546.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            17000..18501
                     /locus_tag="VQ548_000729"
                     /pseudo
     CDS             17000..18501
                     /locus_tag="VQ548_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819023.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase"
     gene            18513..19262
                     /locus_tag="VQ548_000730"
     CDS             18513..19262
                     /locus_tag="VQ548_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HET2653615.1"
                     /translation="MSDNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSKLKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            19275..20447
                     /locus_tag="VQ548_000731"
     CDS             19275..20447
                     /locus_tag="VQ548_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET2653616.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGTLP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTRQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFIKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            20842..21705
                     /locus_tag="VQ548_000732"
     CDS             20842..21705
                     /locus_tag="VQ548_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET2653617.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRRVVDCFSHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVLWQFLKKMQIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            21991..22224
                     /locus_tag="VQ548_000733"
     CDS             21991..22224
                     /locus_tag="VQ548_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653618.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            22246..22923
                     /locus_tag="VQ548_000734"
     CDS             22246..22923
                     /locus_tag="VQ548_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2653619.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATSLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            22935..23600
                     /locus_tag="VQ548_000735"
     CDS             22935..23600
                     /locus_tag="VQ548_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2653620.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAILFGVSHISNHGWVLTDFFVYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            23672..24898
                     /locus_tag="VQ548_000736"
     CDS             23672..24898
                     /locus_tag="VQ548_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2653621.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICLLNLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPISTLFLRNQPFLNLQTGQSLALLATLEL
                     SALILGSLMSGYLQHTISIKIALYASLLLQLLLLVGFATAHFGLILIFSFLDAFFAGI
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALGTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(25249..25326)
                     /locus_tag="VQ548_000737"
                     /pseudo
     CDS             complement(25249..25326)
                     /locus_tag="VQ548_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            25397..26053
                     /locus_tag="VQ548_000738"
     CDS             25397..26053
                     /locus_tag="VQ548_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HET2653622.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            26043..26366
                     /locus_tag="VQ548_000739"
     CDS             26043..26366
                     /locus_tag="VQ548_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HET2653623.1"
                     /translation="MVSKYLLLAVIFSDLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAV
                     LRLVF"
     gene            26470..27300
                     /locus_tag="VQ548_000740"
     CDS             26470..27300
                     /locus_tag="VQ548_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2653624.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NSSPKPFNYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYQMAV
                     NNISYTKERAEKYLYAAPTVKDPNVLVVKKDDSSIKSLDDVGGKSTEVVQGTTSAKQL
                     EDYNKQHSDNPTILNYTKANLQQIMGHLSDGQFDYKISDKITVETVIKNQGLDNLKVI
                     DLPSDQQPYVYPLLAKGQDELKTFVDKRIQELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            27341..27418
                     /locus_tag="VQ548_000741"
                     /pseudo
     CDS             27341..27418
                     /locus_tag="VQ548_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC protein"
     gene            27522..28352
                     /locus_tag="VQ548_000742"
     CDS             27522..28352
                     /locus_tag="VQ548_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2653625.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPKPFIYEENGELTGYEIEVVRAIFKDSDKYNVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            28506..29360
                     /locus_tag="VQ548_000743"
     CDS             28506..29360
                     /locus_tag="VQ548_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HET2653626.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            29460..30833
                     /locus_tag="VQ548_000744"
     CDS             29460..30833
                     /locus_tag="VQ548_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HET2653627.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            30826..31887
                     /locus_tag="VQ548_000745"
     CDS             30826..31887
                     /locus_tag="VQ548_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HET2653628.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            31889..32581
                     /locus_tag="VQ548_000746"
     CDS             31889..32581
                     /locus_tag="VQ548_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2653629.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(32611..33180)
                     /locus_tag="VQ548_000747"
     CDS             complement(32611..33180)
                     /locus_tag="VQ548_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET2653630.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            33315..33929
                     /locus_tag="VQ548_000748"
     CDS             33315..33929
                     /locus_tag="VQ548_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET2653631.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            33931..35577
                     /locus_tag="VQ548_000749"
     CDS             33931..35577
                     /locus_tag="VQ548_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2653632.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDR
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHRASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            35589..36875
                     /locus_tag="VQ548_000750"
     CDS             35589..36875
                     /locus_tag="VQ548_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2653633.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGCD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            36936..37469
                     /locus_tag="VQ548_000751"
     CDS             36936..37469
                     /locus_tag="VQ548_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2653634.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRTAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKASAEEEETEELA"
     gene            37547..38017
                     /gene="nrdI"
                     /locus_tag="VQ548_000752"
     CDS             37547..38017
                     /gene="nrdI"
                     /locus_tag="VQ548_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HET2653635.1"
                     /translation="MKIISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(38310..39572)
                     /locus_tag="VQ548_000753"
     CDS             complement(38310..39572)
                     /locus_tag="VQ548_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HET2653636.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFSGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
BASE COUNT        12053 a         6875 c         8561 g        12201 t
ORIGIN      
        1 ctggtactat cttgaagcat caggtgctat gaaagcaagc caatggttca aagtatcaga
       61 taaatggtac tatgtcaatg gtttaggtgc ccttgcagtc aacacaactg tagatggcta
      121 taaagtcaat gccaatggtg aatgggttta agccgattaa attaaatcat gttaagaaca
      181 tttgacattt taattttgaa acaaagataa ggttcgattg aatagattta tgttcgtatt
      241 ctttaggtac ctatcttatg atttcaggaa atgtcattaa aaaaacgact ccttttctct
      301 aacttgaaaa atagattaga gaaaatgggt tgttttattt attatagtta tttgaatgaa
      361 gataagaaga aggtatactc acatcattca cataatctgt atgttgacta taagtttaaa
      421 aaaacaattt ttaagctctt ccttgtcttc tccaaccaag cgtgttataa tgaatactgc
      481 tcaagcgacc ttcaatcgtg aagcacacac gaccttcaat cgtgaataaa cgaatagatg
      541 ggagacttac catgagtgat aactctaaaa cacgtgttgt cgtggggatg agtggtggtg
      601 ttgattcgtc ggtgacggct cttttgctca aggagcaggg ctacgatgtg atcggtatct
      661 tcatgaagaa ctgggatgac acagatgaaa acggcgtctg tacggcgacc gaagattaca
      721 aggatgtggt tgcggtggca gaccagattg gcattcccta ctactctgtc aattttgaaa
      781 aagagtactg ggaccgcgtt tttgagtatt tcctagcgga ataccgtgca gggcgcacgc
      841 caaatccgga cgttatgtgc aacaaggaaa tcaagttcaa ggcctttttg gactatgcca
      901 tgaccttggg ggcagactat gtagcgactg ggcattatgc tcgagtggcg cgtgatgagg
      961 acggcactgt tcacatgctt cgtggcgtgg acaatggcaa ggaccagacc tatttcctca
     1021 gccaactttc gcaagaacaa ctccaaaaaa ccatgttccc tctgggacat ttggaaaagc
     1081 ctgaagtacg cagactagca gaagaagcag gcctttcgac tgctaagaag aaagactcga
     1141 cagggatttg ctttatcgga gaaaagaact ttaaaaactt tctcagcaac tacctgccag
     1201 ctcagcctgg tcgcatgatg actgtggatg gtcgcgatat gggcgagcat gcaggtctta
     1261 tgtactatac aatcggtcag cgtggcggac tcggtatcgg tgggcaacac ggcggtgaca
     1321 atgccccttg gttcgttgtc ggaaaagatc taagcaagaa tattctctat gtaggacaag
     1381 gattctacca tgattcgctc atgtcaacta gcctagaagc cagtcaagtc cactttactc
     1441 gtgaaatgcc agaagagttt acgctagaat gtacggctaa attccgttac cgtcagcctg
     1501 actctaaggt gaccgtccat gtcaaaggag acaaggcaga agttatcttt gcggaaccac
     1561 aacgcgcgat tacaccagga caggcagttg tcttttacga tggcgaagag tgtctaggtg
     1621 gcggtttgat tgacaatgct taccgcgatg gacaagtttg tcagtacatt tagattgaca
     1681 aattttctca atttgctaca ataataacag caatagaaat gatggtcaaa gctcatggat
     1741 gttgcaggct tttttgtcct gcacttcttt gtagttttga ctgtttttgt gtcgtttaag
     1801 ggaaaggaca agaatgactc aacaagactt tcggacaaaa gtagacaata cggtttttgg
     1861 tgttcgggct acagccttga ttgtccaaaa tcacaagctt ctagttacca aagacaaggg
     1921 caagtattac actattggag gtgcgattca agtcaatgaa agcacggaag acgcggtagt
     1981 ccgtgaagtg aaggaagaac tggatgtcaa agctcaagct gggcagctag cttttgtggt
     2041 tgaaaatcgt tttgaagtgg acggcgtttc ctatcacaat atcgagtttc attatctggt
     2101 ggatttgctt gaagatgccc cgttgaccat gcaggaagat gagaaaaggc agccctgtga
     2161 gtggattgac ttggataagc tccagaatat ccagctagtt ccagcctttt taaaaacagc
     2221 cctaccagat tgggaaggcc aactaagaca cattcatctt gaggaatagg agagaaacat
     2281 gacttatcat tttactgaag aatacgatat tattgtaatt ggtgcgggac acgctggggt
     2341 tgaggcttcc ttggccgcta gccgtatggg ctgtaaggtc ctgcttgcga ccatcaatat
     2401 tgaaatgctg gctttcatgc cttgtaatcc ctctatcggt ggttctgcta aggggattgt
     2461 cgtacgtgaa gtcgatgccc tcggtggcga gatggccaag accattgaca agacttacat
     2521 ccagatgaag atgctcaaca cagggaaggg accagccgtt cgtgcccttc gtgcgcaggc
     2581 tgataaggaa ctttactcta aggaaatgcg caagacagtt gaaaatcaag aaaatctgac
     2641 ccttcgtcaa accatgattg atgagatttt ggtggaagat ggcaaggttg tcggtgtgcg
     2701 tacagccacc catcaagaat atgctgctaa ggctgttatt gtgacgacag ggactgctct
     2761 ccgtggggaa attatcatcg gagacctcaa gtactcatca ggtcctaacc acagcttggc
     2821 ttctattaac ctagctgaca atctcaagga actgggtctc gaaatcggtc gtttcaagac
     2881 aggaacccct ccacgtgtca aggcttcttc tatcaattac gatgtgacgg aaattcagcc
     2941 aggagacgaa gtgcctaatc atttctcata cacttcacgt gatgaggatt atgtcaaaga
     3001 tcaagtgcca tgctggttga cctataccaa tggtaccagt catgagatta tccaaaacaa
     3061 cctccaccgt gcgcctatgt ttacaggtgt ggtcaaggga gtggggcctc gttactgtcc
     3121 gtcgattgaa gacaagattg tgcgctttgc ggacaaggaa cgtcaccaac tcttccttga
     3181 gccagaaggg cgcaatactg aggaagtcta tgttcaagga ctttcaacca gtctgcctga
     3241 ggatgtccag cgtgacttgg ttcattccat caaaggtttg gaaaatgcag agatgatgcg
     3301 gacaggttat gctattgagt atgatatggt cttgcctcat cagttgcgtg cgactttgga
     3361 aaccaagaaa atctcaggtc tcttcactgc tggtcagaca aatggaacat caggttatga
     3421 agaagctgct ggccaaggga ttatcgcggg tatcaatgcg gctctgaaaa tccaaggtaa
     3481 acctgagttg attctaaaac gaagtgacgg ttatatcggg gtgatgatcg acgacttggt
     3541 gaccaaggga accattgaac cttaccgtct cttgaccagt cgtgctgaat accgtctcat
     3601 tcttcgtcat gacaatgctg atatgcgctt gactgagatg ggacgcgaga ttggccttgt
     3661 ggatgatgaa cgctgggctc gttttgaaat caagaaaaat caatttgata atgagatgaa
     3721 acgcctagac agtatcaaac tcaagccagt caaggaaacc aatgctaagg ttgaggaaat
     3781 gggcttcaag ccgttgacag atgcggtgac agccaaggaa ttccttcgcc gtccagaagt
     3841 ttcttaccaa gatgtggtgg ccttcatcgg accagctgca gaagacttgg atgacaagat
     3901 tatcgaattg attgaaacag aaatcaagta cgaaggctat atttccaaag ccatggatca
     3961 ggttgctaag atgaaacgta tggaagaaaa acgcattcca gccaatatcg actgggatga
     4021 catcgattct attgcgacgg aagctcgtca gaagttcaaa ctcatcaatc cagaaaccat
     4081 cggccaagcc agccgtattt cgggagtaaa cccagcagat atttctattt tgatggtgta
     4141 tctggaaggt aaaaatcgta gtatttctaa aactcttcaa aaatcaaaat gatacgtcgt
     4201 cggcttctta cgaatgagtt caaagcttgg ctttgattca tctccaacct cccatagttc
     4261 cccgaactat gggagctaac tcaagttatg cattttccta gccttctggt ctgattttca
     4321 ttgagtttta atctcaaaag aaagcataga gaaaaacagc tccgaagacg gggctgtttt
     4381 gttgacttgt actcaatgaa aatcaaagag caaactagga agctagccgt aggttgctca
     4441 aagcactgct ttgaggttgt agatagaact gacgaagtca gctcaaaaca cagttttgag
     4501 gttgtagata gaactgacga agtcagctca aaacacagtt ttgaggttgt ggatagaact
     4561 gacgaagtca gtaacatata tacggcaagg cgaagctgac gtggtttgaa gagtattatt
     4621 cttcatctgg tgtgaggatc atcgggatga tgatcggttc acgttcggta ttttcataga
     4681 ggaaggggcg aatagcgttg acaatggcac cattgacaga ttgcacgcta gcatccttat
     4741 ttttcagtgc gatacgaatg gcattgaaga ggatacgctg gctttggcga atcaagtctc
     4801 cagactctct catgtagaca aagcctcggc tgaggatatc tgggccagac agaatcatct
     4861 gcgatttgaa gtcaacagtt gcgactgcca gaacgacacc gtcttcagat agatcgcgac
     4921 gatctttgag gacagctgcg ccaatttcac cgatacgatt tccatcgaca tagatatctt
     4981 gggcgttgaa atgacctgcg atacgagctg agtcagcagt aagggcaagc acatcgccat
     5041 tgctcatgat aaagatattg tctttctcaa caccagtatc cactgctagt ccagcgtgga
     5101 ctttttgcat gcggtattca ccgtggacag gcatgaagta ttttggctta atcaagcgga
     5161 gcatgagttt ttgctcttgc tgaccaccgt gtccagatgt atggatattg ttcactttac
     5221 cgtggataac ttcgacacca gcttcagaaa tgatgttaat cagcttgttg acgctagtag
     5281 tgtttccagg gatgggacta gaagagaaga taacggtatc acctggttgt aattgtactt
     5341 gacggtgggt tccgttggcg atacgagaga gggctgccat aggctcaccc tgactacctg
     5401 tacagaggat aagaacttct cctgcaggat aatctttgat ttcatttggc tcgataaagg
     5461 ttcccttagg agctttgatg tagccaagat cgattccgtt gacaatggcc ttttccatag
     5521 aacgaccaaa gaccgcaatc ttgcgtccag tcttaacagc agcttctgtt gcctgctgga
     5581 gacggaagat atttgaggca aaggatgcaa agatgatacg tccttcaata ccttggataa
     5641 tcttcataat ggactgacca acgacttttt cagagttggt aaaggttggt acttccgcat
     5701 ttgtcgagtc agacaggaga cagagcacgc cttcttcacc aagcgcagcc atacgatgca
     5761 agtccgcagg ttctccaact ggagtaaagt cgaacttaaa gtcacccgta cagacgattt
     5821 tcccttgagg agtatgaatg acaatcccca aaggctctgg aatagagtga gtcgttctaa
     5881 agaaagttgc cttgagattt ttaaaggtca actcggtgtt gtggttgatt tcgtaaagtt
     5941 tggcgttgcg caagaggccg tgttcttcga gtttcccacg gatcaaagcc aaggcaagcg
     6001 gtccagcgta gatagggaca tttgcttgct tgagtaggaa cggaatccca ccaatgtggt
     6061 cctcgtgtcc gtgtgtgatt aaaacagcct tgacgcggtc gatattgtct acgatgtaag
     6121 agtagtcagg aatgacatag tcgataccaa gcaagtcatc ttctgggaat ttaatcccag
     6181 catcgacgat gataatctcg tcttggtatt caattccgta agtgtttttc ccgatttctc
     6241 ctagaccacc gatggcaaaa acaccgactt cttcaggttt aagagtgtag gccatattag
     6301 aactccgtaa tttcgaaggc gccagtttct ttttcgtaat cgagcaattt gtcagacaag
     6361 agttcgatat attcgatatt gtactctggg cgattttctt cgacaagttg gcgagcagtg
     6421 atacggccct caagttctga gctggcatcg atgtctaggt aaagcgcgcg tgttgtttca
     6481 cggcgtgggc tacgttcttt tgtttcttga taaaaaactt tgtaaatcat atagttcctt
     6541 tctatttaca ggtcagctta ttccaaactt ttagcagata tttgcttgat ttcattccat
     6601 tttgtgtcta gattgacctt gattcgttac aattatttca attataccac aaaatgaaaa
     6661 attagtaaaa gacggaaacg agaaagttag gggacgattt cttcggtaag cgtttgcaaa
     6721 aacaaagaaa atgtgttatg ttgataacgg aagtgaagtt tattacttgt cataattcca
     6781 tatagatttt aagtcaagga ggttgcccta tgtataactt atttgctttt gctatcggag
     6841 ttcgtttgct agcttttatc gtttttgttt tgcgtttatg gaggaaatct tctatttgcc
     6901 aaactggaac gatgacaaac caagttcttg aggaaaatta cctttgtgac tctctactcg
     6961 ctttttctcc tcctcgtgac ctatgtcgtt tggtttgtat tttactttgg attaaatgct
     7021 tagatgccct gcttatgctg gggttttttg tttggggatg tagagatagt agatttacga
     7081 cacgaaaatt ccaccccatc tatcaagatg aggtggtctt tgcatttttc taaaatgata
     7141 tgacaatgga attttcaaag cttattattt ttatgggagt cattgttctg ctcaaaaata
     7201 gagttgaagc ataaaaataa aacaatacaa acagataaat cgaatggtaa agggatggta
     7261 gtaatgttca aatcattgag aatgctgagc aaactgtaag agatgaagac aataaaattt
     7321 atccttctaa aaatgtgttt cttatctagc atgacttacc aaacttttta cgaaggtctt
     7381 ttccaatggt ataacctgcc ataaataaag cgataccaac acctacacca aagccaccct
     7441 tgatttcttg caattcctta ttagaaattt cacgacagtt gttcaaatct ttcatcatat
     7501 taatctcctc ctaaaaaata accagctgcc aaaccagaac ctataagtgc tgttccacct
     7561 gcaatagctt tccaagatac tgctactcca aagataacca agggagcgag accgccatca
     7621 atatctgata attcattttc agataaggat aaaaattgat tgtcaagaat gtcaaaattt
     7681 gtcattgaac tttcctcctt ttttcttgtt cacttttata ttcggaaaag aaaaggaaaa
     7741 gtgagcattt ttttaaatta tttttagtta agtgagggca ctcttgtctg ggggcaaaga
     7801 aaattcccat gtgccatctt ttgtagtata atagtaagca gacaaaaaga taggaatgtg
     7861 ttatgaaagt attagctttt gatacgtcca gcaaggctct ttctctcgct attttagagg
     7921 ataagcaggt tcttgccgag acgacgatta atatcaagaa aaatcacagt attaccctca
     7981 tgccagccat tgattttttg atggagagtt tggactggac gcccaaggat ttggaccgaa
     8041 tcgtggtggc ggaagggcca ggtagctaca caggcttgcg aatcgcggta gccactgcca
     8101 agaccttgac tcatactctg aacattgagt tagttggtat gtctagcctc ttggctctgg
     8161 tgccatatca acaagaaggc ttgttcgttc ctttgatgga tgcgcgtcgc aacaatgttt
     8221 atgcaggatt ttatgaaaat gctaaacctg tcatgccaga agcgcaccta tcttttgaag
     8281 aggtgctaga aaaagtcaag ggtgctagtc aggtaacctt tgtcggagaa gttggcccct
     8341 ttgtggagca gattcaagaa cacttgccaa ggactaatta taaagaaacc ttgcctaatg
     8401 cagccaatct tgctctttta gcttgggaca aggaagcaga ctccttgcat gattttgtgc
     8461 caaattacct caaacgagtc gaggctgagg aaaactggct caagaaccat accgagtctg
     8521 gtgagtccta cattaaacgc ctatgataga aatcaagcga attcaacaac agcctgacct
     8581 agctcaagcc atctacgctg ttatggcagc tgtttaccta gtcagtcctt ggactctgga
     8641 gcaaatccaa gcagatctgt cccaagacca gacttggtat gcattggctt atgatggggc
     8701 agaagtgatt ggatttctag ctgtgcagga gaatcttttt gaagcagaag tcctgcaaat
     8761 cgctgtcaaa ggagcttatc agggtcaggg aattgcgtca gccttgtttg ctcaattgcc
     8821 gacagataag gagattttcc tcgaagtcag aaagtcaaat caacgagcgc aagcatttta
     8881 caagaaagaa aaaatggcgg tcatcgctga gcgaaaggcc tactaccatg acccagtcga
     8941 ggacgccatt atcatgaaga gagaaataga tgaaggatag atatatttta gcatttgaga
     9001 catcctgtga tgagaccagt gtcgccgtct tgaaaaacga cgatgagctc ttgtccaatg
     9061 tcattgctag tcaaattgag agtcacaaac gttttggtgg cgtagtgccc gaagtagcca
     9121 gtcgtcacca tgtcgaggtc attacagcct gtatcgagga ggcattggca gaagcaggga
     9181 ttaccgaaga ggacgtgaca gctgttgcgg ttacctacgg accaggcttg gtcggagcct
     9241 tgctagttgg tttgtcagct gccaaggcct ttgcttgggc tcacggactt ccactgattc
     9301 ctgttaatca catggctggg cacctcatgg cagctcagag tgtggagcct ttggagtttc
     9361 ccttgctagc cctcttggtc agcggcggac acacagagtt ggtttatgtt tcggaggcag
     9421 gagattataa gattgttggg gaaacccgtg atgatgcggt tggtgaggct tatgataagg
     9481 tcggccgtgt catgggcttg acctatcctg caggtcgtga gattgacgag ctggctcatc
     9541 aggggcagga tatttatgat ttcccccgtg ccatgattaa ggaagataat ctggagttct
     9601 ccttctcagg tttgaaatct gcctttatca atctttatca caatgccgag caaaagggag
     9661 aaagcctgtc tacagaagat ttgtgtgctt ccttccaagc agcagttatg gacattctca
     9721 tggcaaaaac caagaaggct ttggagaaat atcctgttaa aaccctggtt gtggcaggtg
     9781 gtgtggcagc caataaaggt ctcagagaac gcctagcagc cgaaatcaca gatgtcaagg
     9841 ttatcatccc ccctctgcga ctctgcggag acaatgcagg tatgattgcc tatgccagcg
     9901 tcagcgagtg gaacaaagaa aacttcgcag gctgggacct caatgccaaa ccaagtcttg
     9961 cctttgatac catggaataa agagtggctc tttgtcaagt gtagtgggta gtcgaaaagc
    10021 tgcaatctgg agagtacgaa attcgtactc tcttttttga tgttcaaagt catcaaaatc
    10081 cgttttttaa aattgttaaa gttccggaaa ccaaaggctt tgcgcttgat aatcttaatc
    10141 aaattattgg tcgcttcaag tttagcgttg gaataaggca gcttaagtgc gttgataatc
    10201 ttatctctat cccttaaaaa agtccaaaag accgtttgaa aaagcggatg aaccgttggc
    10261 agttcttgct caatcaatcc aaagaaatgg tcggcattct tctcttgaaa atgaaagagc
    10321 aggagttgat agagttcgta gtgaacctgt aatccctcag agtaagaaag cagcttatct
    10381 cgtacttccc gatgggttaa gtgcattcga aacgtgggct gatagaatcg tttctgacag
    10441 agcttgaagc tatactggtg tagtaaatca gtccagtgga ctgatttagc ccgagcctag
    10501 aaacgaaaaa gcgagggttc caaaagcgct tgagcgcccg atactccaag gattttcggt
    10561 caaattggtt catgatttgg attcgtactc ggttcatagc tcggctcaga tgttggacaa
    10621 tgtggaagcg gtcaagaaca atcttcgcct ttggaaagag ttgcttagcg agccgataat
    10681 aagggctgta catgtccatg gtgatgacct cgaccagctc ccgaacctct ctctgatagc
    10741 gttggaaatg gtttcgaatc accgcatgag ttcgcccgtc taaaattgcg aggatggatt
    10801 tggactcaaa atcttgggca atgaagctca ttttgctctt tttgaagcta tactcatccc
    10861 aactcataac ttttggcaac ttggtccaat cggtttcaaa cttaaattcc ctcagttttc
    10921 ggatgacggt ggaagttgag accgccaatc tgtgggcaat ctcagtcata gactgctttt
    10981 caaggaggag ctgagcgatt ttttgtctca ccatgttgga aatctggcaa tttttcttga
    11041 caatggatgt ttgagaaacg accaccttaa ggcaattctt gcactgaaag cggcgctttt
    11101 tgagatgcag taccgtgggt aaaccctgac agtcgagaag cggaatttta gaggctttct
    11161 ggaagtcgta tttgatcatc ttcccttgac aatgaggaca aggaggagcg ggggaatcca
    11221 actttgcctg aacgactaga tgggtttggt atttcagaac agacaagatt ttgatatttt
    11281 tgtcttccaa tccgagcaaa tctgtggtat tcttaagttg ttccatatgg accctttcta
    11341 atgagttggt tagacgcttt tcattatagg tcatatgggg ctttttttct acaagaaacg
    11401 accctataat tcctggggtg ggattaccca ctacagaaat tatagagcca aagcattcca
    11461 aagtcttgtc tgactctgga atgttttctg ttcacagttg ttttgtaact gcctaataag
    11521 taaccgcgct ataacgaggt atctaccgag attgtcaatt ctccagtata ctgttataaa
    11581 aaacaaaact ggaggatttt tttatgtcct cccatcgtcc catcgactgt tccgtagctg
    11641 cccaataacg gagtatagtc ggctgaaaca agaataggac aaaagtgcct caagaaaagc
    11701 atcgtaattt gacaatatta ttctgagatg tttttgatgt aagcccatat tttctcaatg
    11761 ggattatact cgggtgaata ggtaggaagt ggtaacagtc tatgccctgc tccttacaca
    11821 tgttcattct gtgaaacctt gcattgtcca taatgataag ggatggtgta tctaaagtag
    11881 gtagtaagaa tttttggaag caagcttcga aaaagtcact cgtcatcgta tctttatagg
    11941 tcatcggagc catagtatat tgaaacaaaa aagggcatta gtacttctat aacagtatcg
    12001 caatctctgg tgtgcgttgt ctcgatctta attcaaataa ttatatcttc ttccagagag
    12061 actaactgcc tgctcaaggc tcgatcatat ttgagataaa aataggtctc aacccctgtc
    12121 tcataaatat aaataggagt caggtagctt aagtgattca attctttaag gaaccgattt
    12181 actttttctg ggtcttgttc gcagtaggta cggctctttt tagactatat cccatagcct
    12241 ttagagcgta atgaatagtt gttggaggac agttgaattc agcagctatt tcagtcaaat
    12301 aagcatcggg atgagtttca atatagatct ttaatttatc tctatcaact ttttcaatta
    12361 atagtggaag ttttcttaaa gttagtgtgt tgaaacgttt ttatacagtg ctaaaatttg
    12421 aagtgtagtg cagatgtatt tgtaatagta ttatagcaat tctttggaga aggtcgagac
    12481 aagagaaaat aggtatcttt gagatataag tatgatttac tataaaatta ttgagttatt
    12541 cataaaaatt tctctatcaa atatcataat gcgtcgttta aggagatggt tacaatgcaa
    12601 tatagttgtg gaaaaataaa tattaatatc cctgatggat atggagacat taaggatata
    12661 gtgttttcgg ctcatattat agttaggtat aataatggac attgtggagg tatagatccg
    12721 catataattg gactttgtaa aaagcagatc agaaggatgt ctccatatcc tattttgata
    12781 atcgtatcta gagattcaaa ggttattgat gattataaaa atttagatat tgcctatgtt
    12841 gattgtactc aatgttcaaa taattttgaa actgccttac acgttaaaaa tattttaaaa
    12901 ttattaaaaa tccaacttat acactgtcat ggctactcaa ctaattattt tttatatatg
    12961 ttaaaaaaac ttgacaagaa tggatttgga aaggttaaga cagtgataac atgccatgga
    13021 tgggttgaat ataacttaaa aaagaaattc ttgacttatt ttgatttttg gacatattct
    13081 atgggagatg cttttatttg tgtatctgaa actatgaaaa aaagattgga gagtataata
    13141 aaaaaataag aagatagttg caataaataa cggaattaat gtatcaaata gcgatttaga
    13201 tgtagtaggt gttcaagact ttaaaaaaga attttgtatt ccaaataaca aaaaaatcat
    13261 ttgttatgtt ggaaggttgg atccagaaaa aaggccggat agattccttg aatttgcaga
    13321 aaaattattt ttagtcagag aagatgtgat ttttattatg gctggaaatg gtagtatgtg
    13381 ggctactttg aaagaaaaaa tttgccattt gaaatgtaga gataatttca ggttacttgg
    13441 tgaaatctat ccagctacta tagtttacca aatatcggat ttattgtata ttccttctga
    13501 tacagaagga atacctatgt gtgttttaga gtcaatgtca caagaaactc cggttttagc
    13561 tagtaatgtt ggcgggttaa gtgaaattat tgaacatagg gttgatggat ttttatttga
    13621 gaaggaagat gttgagggag tgtgtgcttg tgctaatttt ttactcaatg attctgagta
    13681 tttgaaatat ataggtgaga atagtaaatc aaaaataaga aaacattttt ctgtgcaaaa
    13741 aatgtttgta gaaaccatga gagtatatga tgaattatta gagaagagta gtcatggata
    13801 ggaatataga tcaagaatta gtaagtatta taataccaac acataatagg tatgaatctc
    13861 tgattagagc tgtgaaaagt tgtttacatc aaagttataa aaatatcgaa gttataatta
    13921 ttgatgataa ttatagtaat gtaaatttaa gaaataaaat tatccatcaa tttggctata
    13981 ccagtcatag aattaagtta attttaagta atgaagattt aggtgcaact aatgccagaa
    14041 acataggtat caaaaattct agaggtaagt atatatcatt tttagacgat gatgatgaat
    14101 atatgccaga tcgaatttta aagttgatgg cttgttttaa aaagagtaga atgaagaatt
    14161 tagctttagt ttatagttat ggaataataa tttatccaat aggaaatatt ttaatttatt
    14221 gagtttcaac gagagaatat tggttacaaa gaaatattat tctttaaaca taaagcggtt
    14281 actattaata ggagacaaat gcaaggcttt aaaagtaatc aagaaggcaa gagaagaaaa
    14341 aatttttaac gaatttcttt ttcgaaatat atgttattat atcattttgg ttttttctat
    14401 tgtatatatg acaactatgt tcaattaaaa tttagaaagt gagaaactat tgtgtatact
    14461 attataaaat caaatataaa aaaatttagt ttattaacga tatttattgt tgctggtcaa
    14521 ttattgctaa tttatgcagc aactattaat gctctggtgt tgaatgaatt aattgcgatg
    14581 aatttagagc ggtttttgaa attgtcaatc taccaaatga ttgtctggtg tgggataata
    14641 ttccttgact gggtagtgaa aaattatcag gttgaagtga tccaagagtt taatctagag
    14701 attcgaaata gagttgccac agacatctct aactctacct atcaagaatt tcatagtaaa
    14761 tcatcaggaa catatctttc gtggctaaat aatgatgttc agactttaaa tgatcaggct
    14821 tttaaacaac tttttttagt aataaaagga atttctggta ctatatttgc agttgtgact
    14881 cttaatcact atcattggtc attgactgta gccaccttgt tttcattaat gattatgcta
    14941 cttgtaccaa aaatctttgc atcgaaaatg cgagaagtta gtctaaattt aactaaccaa
    15001 aatgaagctt ttttaaaatc tagtgagact atattgaatg gatttgatgt gttagcgtcc
    15061 ttgaatcttt tatatgtatt gcctaagaaa attaaagaag caggaatttt attaaagatg
    15121 gttatacaaa gaaagacaac tgtagaaacg ttagcaggcg ctattagctt ctttctcaat
    15181 attttttttc agatatctct cgttttttta acaggctatc ttgcaataaa aggaatagtg
    15241 aaaattggta ctattgaagc aataggagca ctaacaggtg ttatttttac agcgctaggt
    15301 gaattaggag gtcaattatc ctctattatt ggtacgaagc ctattttttt aaaattgtat
    15361 tcaattaatc caattgagtc aaataaaatg aatgatatcg aaccaaatga ggtgaataga
    15421 gattttccgt tatatgaagc aaaaaatatt tgctataagt atggagataa agaaatatta
    15481 aaaaacttaa atttttgttt tcaacgtaat gaaaagtatt taattttagg tgaaagtgga
    15541 agcgggaaat ctacattatt aaaattattg agtggctttt tgagagatta tagtggagaa
    15601 ttgcgattct gcggggatga tataaaaaaa acctcctatt taaatatggt ttcgaatgtt
    15661 ctatatgtag atcaaaaagc ttatttgttt gaaggtacga ttagagataa tattttattg
    15721 gaagaaaatt atactgatga agaaatacta cagtctttag agcaagttgg tttgagtgta
    15781 aaagattttc ctaataacat tttagattat tatgttggtg atgatgggag attactgtca
    15841 ggagggcaga aacaaaaaat tactttagct agagggctaa ttagaaataa gaaaatagta
    15901 ttaattgacg agggaacttc tgctatcgat aggagaactt cgttagcgat tgaacgtaag
    15961 atattagata gagaggattt gactgtcatt attgttaccc atgctccgca tccggaactt
    16021 aaacaatatt ttactaagat atatcaattt ccaaaggatt ttatttaaga atatagggga
    16081 gggaaacatg agattctatt gtgaagctta tgaggtaatt actgaagaga aaaaagtata
    16141 ctttaatgat attgagttag aagttaagta ttcctctgtc gaagaattgt ttataatatg
    16201 tgagaaatta ttagataaga aaaaagtatc atttttttat gtatatgaga aacccttaag
    16261 gtatctgtta tttgactata tatttctact agttctagct aaaaaaaata tcccaatctt
    16321 agatggagtt tccaataagc aagttgatcc aacgttgctg catcactttt ctttggaaat
    16381 tgaaaagaat tttatcgatt tttgctataa aaatatggat ctcatcctaa aaactcaaag
    16441 tatatctttg tgtcatagag aagagcttat tattgtagat gtttcagatg actctaaatt
    16501 tggtgttttt tacaagcgtt ttagaacact ggttgataaa aataacggaa aatatgtttg
    16561 tgtttataat ttcagtcgtg tttcagatat actgcaaaac tggaaaaatt attgcaatcg
    16621 aaaattttcg gttacgttta ctgaaagcca atttgaatta tttaagcttt tatataatca
    16681 aaaaaatttt aaaacaattt cgttgctatt tggaaaaaaa ttgttgctgg aggaattatc
    16741 tattatagcg atcttactaa tatagaatac ttttgtattt tttggtggga tagtatgttt
    16801 gggaaagatt ctattggaaa atacgtatat gtagaagaga ttagtagatg tcatttttta
    16861 gatagaaatt attctttttg ttatggttta caagattata aaagtaaact tattaaatat
    16921 tttttagaat agttaatcta ttcgagagag ataaagaaat atggaaaata ctttattgaa
    16981 tatcacagga agcttcgata tggaaactag gaatctaatt agttattctt taactgatat
    17041 ctttgaaaca gataaaataa gaattgaact tcttggagaa atttattata aaaatataaa
    17101 gttggaattg catgaattcg ctggattgta taagatttat ggaattagct taataaagaa
    17161 tattaccgga atgtttttaa ttataatttt tgatacgaag acaaaagaat taaaaatttt
    17221 tcaagatata acgacttcat actttaattt atactatact gtttatggag gtgtgttcta
    17281 tatatagtac atctttaaag aaagtgatga agttatctca tgttcccgtt accttaaata
    17341 acaaaaaaat acaagaattt atgagaaatg gatttatttt agattcaaat actttagtaa
    17401 ccgaaattaa taaattagaa tatttctctt acatttctgt aaataatact cttcgtatat
    17461 gtggtattga ttataatgat tcaaacaatt ttactaaaga acaagtatta aagaattggg
    17521 actctatgct acgtgaatct atattaagag tgtatagtga agcaggagag gctaatatta
    17581 cactatcatc tggttttgat tcaaattata tattatatac attagcgaat tatacgaatt
    17641 cttcaattaa tgcattttgc ataggaggag aaaaaggaat taatgagatt cctgaagtaa
    17701 ctaaaattgc aaaattttat ggtataaatt tattagttga tactgtaatg agcccaagat
    17761 ttagaatatt ttcccgatat agtatggaga ttggaaggaa gtctctttga atgtggtgtc
    17821 atactgcagt actatttagg caggttgttg ttccaaaaag ggaacacaag tattctttgt
    17881 ggcgagtcag cggatgaaat aatgactttt aagtatcatt ctgtgaacta caatcaattt
    17941 tgtaatgata aacagaagtc agtatatttt agttattccg actatccatt ttatgttaca
    18001 aattcaattg ttttaaagaa aaatagccta cttttgcata gttttggcat tcatcctaga
    18061 tatccatata aaatgtctga gattgttgaa atgtctaaaa aaatatcaga tctaaacgat
    18121 aaaaaagaat ttcacaaaaa gaactgtgag ttgaggtttc aagatagtgt tcttgataac
    18181 ataaatagtg tcccgggtac aactcattta tttagttgtt taaatattca aacattagta
    18241 aaaattattt tatatatttt tcgatacaac agttgtatga aaatatttaa ttttagagat
    18301 aaagagctta tcttttttaa taagattgta aatgggctga tacaaaatat tgaggagaat
    18361 ttagaggatg atattgaaag gatattgaaa tatttatata tatgtttatt taacgaaata
    18421 ttcattatta agaataaggt gaattttttt gatgatgtgg aatttaatca gacacttagt
    18481 gagtttttag ataaattgta gagggaatgg ttatgagtga caatactaag tatatctttt
    18541 tatctccaca tttagatgac gcaatttttt cctgtggtga ttatatttca aaattaactt
    18601 cagaaggaga aattgtactt gttattacta tattttctgg ttaccctttg agccaacagc
    18661 tacagccctc tgctaagcaa tttcataagt tgtgtaacct tgggaaatat ccgattgaag
    18721 aaaggaagaa agaagacagg ttagcttgtg aacgtctaca atgtgatttt agacacttat
    18781 cgtactatga atgtctctat aggaaagata gaaatggcaa ttttctatac cgtcatatct
    18841 atagtaaatt aaaaaatgag gacacattaa agaatgatat cataaaagag ctgttaatgc
    18901 atttagacga caaatgtgtc gtatattgtc cgctttcact tggtgaccat gttgatcatg
    18961 tttttgtgaa tagtattgga agggcgcttg aatttatgcg ttataaagta atatattatg
    19021 aggacttccc atatgtaagt gatagtagta tggttagtta tatgggaaaa actaaagaat
    19081 taaaaatgta tcaagaggaa cttgatgaaa aacattatat tgatagaata tcatcaatat
    19141 tgtgctataa atctcagatt ttgataatct ggaaatcagt tgaaaaactt ttaaacaata
    19201 ttaaagagtt gtatttaagg aatggggcag cttattctat tagattttgg attaagaaat
    19261 aaggaagtag ttttatgaat atagcagtaa ttggtttggg gcatgttggg ctggcctacg
    19321 cgttactatt tgcatctaaa tataaagttg ttgcatatga tatagattct gtaaaaataa
    19381 ataatttaaa aaagggcact cttccatcta aaaatgaaga gcttatgaag tttttttgcg
    19441 agaataactt aaatattact ttttttgata cattttctga aattaaaaat aatattgatt
    19501 attatattat tgcgcttccg acagattatg atgagaaaat tggtagtttt aatacatatg
    19561 aaatcgaaca aacggtatcg aagattctga gggtaaaacc taatggaaag attattttaa
    19621 agtcaacagt tccgatcggc ttttcaaaca aattaaaaag gctgtttgat acaaaaaata
    19681 tcatttttgt ccctgaattt ttgagagaag gttgttctat atatgataat ttatatccaa
    19741 gtcgcatagt tgttggagat gagacagttg aaggaagaaa aattgcagag ttgttccttt
    19801 cgattagtac tcatagtact gccaatatta aaaatgttat gttagtttct cctactgaag
    19861 cagaagcaat taagcttttt tctaacacat tcttagctct ccgtgttgct ttttttaatg
    19921 aactagattc ttttgctgag aggagaagtt taaatgctga agttgtaata aaaggtgttt
    19981 gtttagatcc aagaattgga aatttttata ataatccttc ttttggattt ggaggatatt
    20041 gtcttcccaa agatactaga caattaaaaa aagaatttat agaaataaat gccccagtga
    20101 tagaagcgat tgatatttca aacacaaata gaaaacagtt catagttaaa caaatattgg
    20161 aacgaaagcc aaagatagta ggaatatata aattggggat gaaatataat tcagataatt
    20221 acaaagagtc agctatttta agtataatta atgaactatt gattgtcggt ataaaaattt
    20281 tagtatatga accaaattta aacgttagta tagataacgt aatttttgaa aagaattttg
    20341 aactatttat aaaacaaagt gatctaattg ttgcaaatag atgggatagg ggccttgaag
    20401 cttataaaga taaagtttac acaaggggga tctggataag agattaacta ttgatattaa
    20461 aaaggcaata atttataaaa tttgtacaaa aaaatgttaa attttcacat tttcatagta
    20521 tactgtttaa tagaaagtag gttctttgta accgctccat tataaaatcc tttcactctt
    20581 ccggtatact attaggaaaa acataactgg aggatatttt gagctcacac ctcatcgttc
    20641 cagtggctgt tccccaagct cgtgtactgc ccaaaaaagt tagacattct atttagaacg
    20701 aggattgagt tctgtattgt acaaggctcg gtccttttag agtcagctta aggctggctt
    20761 tttcaatcac caaagtgtca gaatgttttg acaaatgaac acaaataatg atataatatg
    20821 caaaagctag gaggtggtag gatgattgaa aaaatggaac tgggggaatt ttacaaggaa
    20881 ttgcgcttgg cgagaaagct caagcagtca gatgtggctt gtgctggact aacagcctct
    20941 cagttgtcca agtttgaact aggacagtct atgctgtctg cagacaagct gatcctagcc
    21001 atccaaggga tcaatatgaa ttttgatgag tttgggcaca aactcaacaa ctatcaagaa
    21061 tctccacata tgcgaattgg tagaagggtt gtggattgct tttcccatca ggatatagct
    21121 gctttagagc agctattgga ggaagtcgat caagaacaga tggcgcagac ctatcgtcgt
    21181 ttgaatgcca ttgtgattaa aaatgcactc cattccttag ataaaagcta cccgctaaca
    21241 gaggaggata gcgagttttt gactacctac ctctacgcta ttgagtcttg gacctggttt
    21301 gaactctatc ttttttgcaa tactatgccc ttcttgagca atcaagatct gatcttttta
    21361 tcaacctcct tactcgaaaa atccaaggaa tttaaagagt tagtacacaa tcgatggtat
    21421 atgaaaagtg gttatcttaa tatcatctca gaacttatgg agcgcaagct attttcttat
    21481 attccaatct ttgaagctga gctggagcgc atgctccgtc catacgatgt ttttgaaaaa
    21541 gtattgtggc agtttttaaa gaaaatgcag atttttcttc aaaccaaagg aagcaatcaa
    21601 aaagagattg aacactttat ccaatctctg caagtattag aaaatccaca attgacagcc
    21661 ctttttgaat tgcgtttgca gcaatacaaa gagcttatcg attagttaga aatgggaaaa
    21721 agataataat atcagcaacg atcgtcaata atgttaaaac ttgtttcttc atattacttc
    21781 cctcctcatt agtaataact ttattatacc agggaaataa tcaaatctac caaaatcgca
    21841 aatctgaaat ttctataaga aaaaatatca aatatgcgat tttctaaaat aagccaattt
    21901 ccgtgttata ctgtccttgt aaaacatttg aagcaaatcc taggtcgcag aagtggttta
    21961 caaatgaaga taattgaagg agtgtaaaag atgttaaatt tacaatttgc agaaacaatg
    22021 gaattgacag aagctgagtt gcaagatgtt agaggaggca acctcgtaaa ttctatggga
    22081 ggtggtggaa gaagtggtat atctggttgg ggcgtcccag gaatttaccc tggttggggc
    22141 aatcaaggga tgagtcctaa tcgtggagct tttgattgga ctatagattt agcagatgga
    22201 ttgtttggcc gccgtagaag ataggctctt ataggagata ataggatgaa gaaaatgaaa
    22261 gaagtgaaat ttcacctagc aactggcttg ttgattttga cttattacct catttttaat
    22321 gtcacatcag acttagattt tatggttgct ttgtctgata atatgtacta tgtgttccaa
    22381 gttttattgg tacttattct gggaactata gctacaattg cttttgtcaa aagtgaacat
    22441 tggaaagagt gtggtcgttt ccagtttcgt tggtcttacc tgggtgtttt ccttctttct
    22501 tttttcttat tgttcgtgtg ggcaaatcta acaacctata tctttcctcg tacccagaat
    22561 ggaagtacag tcgtagaagt agccaccagt ttaacaggaa ttagctattt tgttacgcga
    22621 atactttata ctagtattat cgcacctgta tcagaagagg ttgtttgtcg tggtcttttg
    22681 atgacaagtt tatctaaagt taagagatac tatcttgatg ttcttgtttc cgctgccata
    22741 tttggcgcta tgcatgtttt gcagtatggt tggataacga cagatttcat aaagtatttt
    22801 ggaatgggct tgatattttg tatgatgttt cgctacaccc gatccatcta ttgggctata
    22861 gctctgcatg cttcatggaa tagcttctta ctcattgtta ctttattggt atttggatat
    22921 tagaaaggtg atatatgaaa aagataatct cacaccgcta ctttattata gtttttctac
    22981 tagttattgc tgaccagaag ttcagtgttt tagttttacg cagcgacctt gttgctgggc
    23041 tatctgactt tgcctattat ctgtcggata tgatgttgaa ttttcttgtg gttttatttg
    23101 ctcttattgc tatgatttgg tcggggaaat ggcagaaaat caatagtaga aagtttaaag
    23161 gatcctatct tttctattcc ttcctagctc tgcttgcttt tgttgcttgg aattttgtca
    23221 ccttttttct tttcccacct actcgaaatg aaatttctta tcaacatgct gctcctactt
    23281 ttacaggagc tacggcattt ttgatgtatt ttttttatcc tgtgattgca ggtcccattt
    23341 ttgaagacat gatttatcgt ggattggtga tgacagctct ggaaaaagga aagaaatggg
    23401 ggctagatgt acttggttct gctattttat ttggggtctc gcacattagt aatcacggtt
    23461 gggtcttgac agactttttc gtctatatgg gtggcggact tatatttgca gtcttattta
    23521 gaatgacaaa gtccatttat tggcctattg ggctgcatat agtctacaac ggcattggtc
    23581 agcttttgat gttactgtaa ttttggttgt tagtagtatc gcggtctatt tctggggaaa
    23641 gattcccatt tgaacttaag aaggagttgt gatgaaagta tttcttcaaa atagagattt
    23701 taggcaatta actatcaacc agtggatttc aacgcttggg gatacgattt tttatctggc
    23761 cttcctgaat tatgtggcag atgcgtcttt tgcccctttg gcgattttac ttatcacgat
    23821 ttcagaaacc cttccccaag ttctacaaat ctttctggga gttttggcgg attttcaaca
    23881 tcatcgtgtc ttgaaataca cagtcattag ttttacaaaa tttttgcttt actctatagt
    23941 gtccctatcg ctttcagggc agtctttttc cttgttgcta gtaaccttta tttgtctgct
    24001 taacctcttg tctgacacat tgagttattt ttcaggcgcc atgctcactc cgattttcat
    24061 tagaattatt gggcaagacc atctggcaga agctattgga tttaaacagt caactgttag
    24121 tttagtgaaa acaatcagta atatcctagg aggagtctta ctaggcattc tatccatcca
    24181 gtttatttcc ttactgaacg ctcttacctt tttaatcgca tttttaggta tcctcttcat
    24241 aaaaactgac ctcttgaaag tagaaaaaac gattagctat caagaaggac tctctgtaaa
    24301 atccttttgc cagcatttgc tccaatcatc gaaattgata tggaatatga ataaggtgct
    24361 cttggttttg tttattatct ctactagtca agcagtgata aatgttacgg ttcctatttc
    24421 cactctattt ttaaggaacc agcccttttt gaatttacaa actggtcaat ctcttgcctt
    24481 gttagccaca ctagaattat cagcccttat tttgggaagt ctgatgagtg gctatctgca
    24541 acataccatt tccataaaaa tagccctgta tgcttcactc ctactccaat tactactcct
    24601 agtgggcttt gcgacagctc attttggctt gattctgatc tttagctttt tggatgcctt
    24661 tttcgcgggt attctctctc ctagattgca agaactcgtc tttaaacaaa tacctgagga
    24721 gtcaatggga gcagttcaat cttctatcgg tgccattacg gttgttttac ctagcttatt
    24781 tacaatagct ttgggaacca ttgctactag ctttggaact ctggcagtta gctttgtttt
    24841 attactattt cttctagttg cctttgtcat gcttctgaat attcgtgaaa gtatttagtg
    24901 gagaatttct ataatatatg tttgagactg gattgccagt ctttttatga tggtcaaaat
    24961 caacagactt tttctctttt ctgaatgtgt tatagtagac tgaatctaaa atagtacgaa
    25021 ataattgcta aaacatttat agaaattaat tttactttcc caatcgattt gttctcatct
    25081 tatttcaatc tgctatataa tagtccatgc tgtggctgga ttcttttcag cctacttata
    25141 ctcttcgaaa ctctcttcaa accacgtcag cttcaccttg ccgtaggtat ggttactgac
    25201 ttcgtcagtt ctatccacaa cctcaaaaca gtgttttgag ctgacttcgt cagttctatc
    25261 tgcaacctca aaacaatgtt ttgagcaacc tgcggctagt ttcctagttt gctctttgat
    25321 tttcattgag tattattaag acaatatgag gagaaagatg aaagaaaaag gattttagga
    25381 gggggcgcag gcagccatgc caacggctct tggctatgtc agtatcggcc tggcctgtgg
    25441 gactatcggt gcgccctatg tgacacctgt tgagatgggc ttgatgagtc tctttgttta
    25501 tgctgggagt gcccagtttg ccatgttggc actgattgtg gttcaagctc ctgtggcagc
    25561 tattgctatg acggtttttc taatcaactt gcgtctcttt ttgttgagtt tacacgcatc
    25621 gacttatttc cgtcatacca gtctttggta caatatcggt atgtctagta tcttgacaga
    25681 tgagacctat ggcgttttga tgggtgaatt ggcccataca gacaaggtaa atcctatgtg
    25741 gatgcacgga aacaatctta acagctatgt ggcttggttt gtggggacag tagtcggaac
    25801 ggctctgggt ggcctgctac caaatccaga aatctttggc ttggattttg ccctggttgg
    25861 gatgtttatt ggtatttttg cttcgcaatt tcagattatg caaagacgga ttcctgtccg
    25921 caatctgctc attatcctag cagttgttgc ggtgtccttc tttttgctct tgacagtggt
    25981 gtctcagtca ctagctgttc tgtttgcgac gctacttggt tgtagcatgg gggtggtttt
    26041 agatggtcag taagtatctt ttattagcag ttattttctc tgacttggtg acttggattc
    26101 tccgtatgat tcccttcatc ttagtcaagt ataagggctt gcctgcaatc gttgagcgtt
    26161 ttttgaagtt cttgcccgtt tccattatct ttgccttgat tctttcaagc gtagtgacag
    26221 gtaaggttgg gagccttcct caaattaaat ggctagactt cttagccgtc tttccaacag
    26281 cttgggtagc ctttcgctac cgcaatctag tcggaacagt tctctttgga gtagtcttga
    26341 ttgccgtctt gcgtttggtc ttttaaatca gccataaaga aaacctatca cagatatata
    26401 tatcatataa tggtgtaaat gatttttttc tgttaagatt ataaggtatt ctattttgga
    26461 ggaaatgaca tgaaaaaaat cgttaaatac tcatctcttg ctgccctagg gcttgttgct
    26521 gcaggtgtgc tagcagcttg ctccggtggt gctaagaaag aaggacaagc agctagcaag
    26581 aaagaaatta ttgttgcaac taattcttca ccaaaaccat tcaactatga agaaaatggc
    26641 gaattgactg gttacgagat tgaagtcgtt cgcgctatct ttaaagactc tgataagtat
    26701 gatgtcaagt ttgagaagac agagtggtca ggtgtctttg cgggtcttga cgctgaccgt
    26761 taccaaatgg ctgttaacaa catcagctac actaaagaac gtgcggagaa atacctttat
    26821 gcagccccaa ctgttaaaga ccctaacgtt cttgtagtca agaaagacga ttctagcatc
    26881 aaatcgcttg atgatgttgg tggaaaatca acagaagttg ttcaaggaac aacatctgct
    26941 aaacagttag aagactacaa caaacaacac tcagataatc caactatcct taactatact
    27001 aaagcaaact tacaacaaat catgggccac ttgagcgatg gtcagtttga ctacaagatt
    27061 tctgataaaa tcactgttga aacagtcatc aagaaccaag gtttggacaa cttgaaagtc
    27121 atcgatcttc caagcgacca acaaccttac gtttacccac ttcttgctaa aggtcaagat
    27181 gagttgaaaa catttgtaga caaacgtatc caagaactct acaaagacgg aactcttgaa
    27241 aaattgtcta aacaattctt cggagacact tacctaccgg cagaagctga tattaaataa
    27301 tttcttgaaa tcatccattc tgagtaagat gggtgatttt tcagttcgct accgcaatct
    27361 agtcggaaca gttctctttg gagtggtctt gattgccatc ttgcgtttgg tcttttaaat
    27421 tacccataaa aaaaacttat cacagagata gatatcatat aatggcgtaa atgctctttt
    27481 tctgttaaga ttataaggta ttctattttg gaggaaatga catgaaaaaa atcgttaaat
    27541 actcatctct tgcagccctt gctcttgttg ctgcaggtgt gcttgcggct tgctcaggtg
    27601 gtgctaagaa agaaggacaa gcagctagca agaaagaaat catcgttgca accaatggat
    27661 caccaaagcc atttatctat gaagaaaatg gcgaattgac tggttatgag attgaagtcg
    27721 ttcgcgctat ctttaaagat tctgacaaat ataatgtcaa gtttgaaaag acagaatggt
    27781 caggtgtctt tgctggtctt gatgctgacc gttacaatat ggctgtcaac aatcttagct
    27841 acactaaaga acgtgcggag aaatacctct atgccgcacc aattgcccaa aatcctaatg
    27901 tccttgtagt gaagaaagat gactctagta tcaagtctct cgatgatatc ggtggaaaat
    27961 cgacggaagt cgttcaagcc actacatcag ctaagcagtt agaagcatac aacgctgaac
    28021 acacggacaa cccaactatc cttaactata ctaaggcaga tttccaacaa atcatggtac
    28081 gtttgagcga tggacaattt gactacaaga tttttgataa aatcggtgtt gaaacagtga
    28141 tcaagaacca aggtttggac aacttgaaag ttatcgaact tccaagcgac caacaaccgt
    28201 acgtttaccc acttcttgct cagggtcaag atgagttgaa atcatttgta gacaaacgca
    28261 ttaaagaact ctacaaagac ggaacgcttg aaaaattgtc taaacaattc ttcggagaca
    28321 cttatctacc ggcagaagct gatattaaat aatttcttga aatcatccat tctgagtaag
    28381 atgggtggtt tctcagtttt tagggatata gttttaaact atatatctga ctatctaata
    28441 acaatttgtg aaatcaaaca aattgtgaga tactagtacg gtattatttt taaggagaaa
    28501 gaatcatgaa aatcaaaaaa tggcttggcc tagcagccct tgctacagtc gcaggtttgg
    28561 ctcttgcagc ttgcggaaac tcagaaaaga aagcagacaa tgcaacaacg atcaaaatcg
    28621 caactgttaa ccgtagcggt tctgaagaaa aacgttggga caaaatccaa gaattggtta
    28681 aaaaagacgg aattaccttg gaatttacag agttcacaga ctactcacaa ccaaacaaag
    28741 caactgctga tggcgaagta gatttgaacg ctttccaaca ctataacttc ttgaacaact
    28801 ggaacaaaga aaacggaaaa gaccttgtag cgattgcaga tacttacatc tctccaatcc
    28861 gcctttactc aggtttgaat ggaagtgcca acaagtacac taaagtagaa gacatcccag
    28921 caaacggaga aatcgctgta ccgaatgacg ctacaaacga aagccgtgcg ctttacttgc
    28981 ttcaatcagc tggcttgatt aaattggatg tttctggaac tgctcttgca acagttgcca
    29041 acatcaaaga aaatccaaag aacttgaaaa tcactgaatt ggacgctagc caaacagctc
    29101 gttcattgtc atcagttgac gctgccgttg taaacaatac cttcgttaca gaagcaaaat
    29161 tggactacaa gaaagcactt ttcaaagaac aagctgatga aaactcaaaa caatggtaca
    29221 acatcattgt tgcgaaaaaa gattgggaaa catcacctaa ggctgatgct atcaagaaag
    29281 taatcgcagc ttaccacaca gatgacgtga aaaaagttat cgaagaatca tcagatggtt
    29341 tggatcaacc agtttggtaa taagaaacag ggaggtggga gagaaaattc cacctcttgc
    29401 ttttgtatag agtatagatt gtaaagaaga ctattcgttc atagaaaggt agagagaata
    29461 tggtttttcc tagcgaacaa gaacagattg aaaaatttga aaaggatcat gtagtccaac
    29521 attattttga ggttttgcgt accttgattt ctaagaaatc agtctttgcc cagcaggttg
    29581 gactcaagga agtcgcaaat tatctgggtg agattttcaa gcgtgttgga gctgaagtgg
    29641 agattgatga gagctataca gcgccctttg tcatggcaca tttcaagagt tcgcgtccag
    29701 atgccaagac cttgattttc tataaccact atgacactgt gccagcggat ggggatcagg
    29761 tctggacaga ggatcctttt acgctttcgg tccgcaatgg cttcatgtat gggcgtgggg
    29821 ttgatgacga caagggtcat atcacagctc gcttgagtgc tttgagaaaa tatatgcagc
    29881 accatgatga tttacctgtc aatatcagct ttatcatgga gggagcggag gaatcggctt
    29941 caacagacct agataagtat ttggaaaagc atgcagacaa actccgtggg gcggatttgt
    30001 tggtctggga acaagggacc aaaaatgcct tggaacagct ggaaatttct ggtggcaata
    30061 aggggattgt gacctttgat gccaaggtaa aaagcgctga tgtggatatc cactcgagtt
    30121 atggtggtgt tgtggaatca gctccttggt atctcctcca agccttacag tctcttcgtg
    30181 ctgcggatgg ccgtatcttg gttgaaggct tgtacgaaga agtacaagag cccaatgaac
    30241 gagaaatggc cttgctagaa acttatggtc aacgaaaccc agaggaagtt agtcggattt
    30301 atggattgga gttgcctctc ttacaggagg agcggatggc ctttctaaaa cgtttctttt
    30361 tcgagccagc gcttaatatc gaaggaatcc agtctggtta tcaaggtcag ggtgttaaga
    30421 ctattttacc tgcagaagcc agtgccaagc tagaggttcg tctggttccg ggcctagaac
    30481 cgcatgatgt tctggaaaaa attcggaaac aactagacaa aaatggcttt gataaggtag
    30541 aattatacta taccttggga gagatgagct atcgaagcga tatgagcgca ccagccattc
    30601 tcaatgtgat cgagttggcc aagaaattct atccacaggg cgtttcagtc ttgccgacga
    30661 cagcggggac aggacctatg catacggtct ttgatgccct agaggtacca atggttgcat
    30721 ttggtctagg aaatgccaat agccgagacc acggtggaga tgaaaatgtg cgaatcgctg
    30781 attattacac ccatatcgaa ttagtagagg agctgattag aagctatgag tagagatatt
    30841 atcaagttag atcagatcga tgtgactttt caccaaaaga agagaaccat cacagcggtt
    30901 aaggatgtga ccattcacat ccaagaaggg gatatctacg gaatcgttgg atattctgga
    30961 gcagggaaat caacccttgt acgggtgatt aacctcttgc aaaaaccatc tgcagggaaa
    31021 attaccattg acgacgatgt gatttttgat ggtaaggtca ccttgacggc agagcagttg
    31081 cgtcgtaaac gtcaagatat cgggatgatt ttccagcatt ttaacctgat gagccaaaag
    31141 acagcagagg agaatgtagc ctttgccctt aaacactctg gactcagcaa ggaagaaaag
    31201 aaggctaaag tagctaagtt gttggacttg gttggtttgg cagatcgtgc tgaaaactac
    31261 ccttcacaac tatctggagg gcaaaaacag cgtgtggcaa ttgcgcgtgc cttggccaat
    31321 gatccaaaaa tcttgatttc agacgagtca acttctgccc ttgatccgaa gacaaccaag
    31381 cagattttgg ccttgttgca agatttgaac caaaaattag gcttgactgt tgtcttgatt
    31441 acgcatgaaa tgcagattgt caaagacatt gccaaccgtg ttgcagttat gcaggatggg
    31501 catttgattg aagagggtag tgtgcttgaa atcttctcaa atcctaaaca acctttgact
    31561 caagacttta tctcaacagc tacaggtatt gacgaagcca tggtcaaaat cgagaagcaa
    31621 gaaatcgtgg aacacttgtc tgaaaacagt ctcttggtgc aactcaagta cgctggagct
    31681 tcaacagacg agccactttt gaatgaattg tacaagcatt accaagtaat ggctaatatt
    31741 ctctatggga atatcgaaat tctcgatggt actcctgttg gagaattggt ggtggtcttg
    31801 tcaggtgaaa aagcagcgtt ggcaggtgcc caagaagcca ttcgtcaagc aggtgtacaa
    31861 ctaaaagtat tgaagggagg acagtaagat ggaatcattg attcaaacct atttaccaaa
    31921 tgtctataaa atgggttggg ctggtcaggc aggctgggga acggctatct acttaactct
    31981 ttatatgaca gttctttcct tcattatcgg aggcttcttg gggctagtgg caggtctctt
    32041 tctcgtcttg acagcgccag gtggtgtctt ggagaataaa gtcgtattct ggattttaga
    32101 caaaattacc tcaatttttc gtgcagttcc ctttatcatc ctcttggcaa tcttgtcacc
    32161 actttctcac ttgattgtta aaacaagtat cgggccaaat gcagcccttg tcccactttc
    32221 ttttgcagtc tttgccttct ttgcccgtca ggtgcaggtt gtcttggctg aattggatgg
    32281 cggtgtcatt gaggcggctc aagcgagcgg agcgactttc tgggacatcg tgggtgttta
    32341 cctatcagaa ggtcttccag atttgatccg tgtgacgact gtgaccttga tttcccttgt
    32401 tggggaaaca gctatggccg gtgcggttgg agctggtggt atcggtaacg tagccatcgc
    32461 ttatggattt aaccgctaca atcacgatgt gaccatcttg gcaaccatca ttatcatttt
    32521 gattatcttt gcaatccaat tcttgggaga tttcttgact aagaaattga gccataaata
    32581 aaaaagagcc gcgtggctct ttttaactga tcagattttc tgtgcaaatt ttttactcaa
    32641 ggcttgtcca atcaaggcac ccactagggc tccgatgaca atacttgcga taaatagaag
    32701 gacagttcca gggtttggag cgaccatgat gcggtcgata tattcttggg attttcctct
    32761 tgccagaaga gtagccatat aggctttggg cgcaatccac ataagcaaga ttggtcctgt
    32821 tgtactaaag gcgaaaataa tgaaagaaag gaagttcttt gttttgtcct tgtattttcc
    32881 taaatgagct actccatctg ctaggaggcc acagataatt ccaggaagga aggaaccagc
    32941 accgtgttta gttcccaaga aaaagagggc aatgacaagg ccgatagtgg taatggctcc
    33001 aaagcgcgga acttttgcga ctaggatcat atagacgcta ccgccgacaa gggcagtaaa
    33061 ggcaggcgca taaaacatgt ttccagtttg gtcaaagaga ttgcccaaaa ggacaccaat
    33121 ccccatgcag aggaagtaaa gaactgcaaa aagcagtgta gttaagatag atttcttcat
    33181 gaattgtctc ctgataattt tttcacaatt ctcattttac catggtttgg tgggattgta
    33241 aatggatact agaagttttt gaaaacgctt gaaatatgat ataatggttt catagttatt
    33301 tttaggggaa tatcatgggt agatttttag actttgtctt taatcgtttc tttttaggga
    33361 tgattgcgac agccttcttt tggctattaa ctttagcagg agggattatc cttggtctag
    33421 cgccggctag tgccaccttg atgagcttat atgcagaaca tggttatagc tttcgggaat
    33481 acagtttgaa ggaggcttgg tctctttaca agcaaaattt tgtctcaagc aacctgattt
    33541 tctatagctt tttaggtgtg ggtctagttt tgacctatgg tttgtatctc ttggtgcaat
    33601 tgcctcatca gactattgtt catttgattg cgaccctttt gaatgtccta gtagttgccc
    33661 tgatcttttt ggcttataca gtatctttaa aattacaagt ttattttgcc ttgtcctatc
    33721 gaaatagtct caaattatcc ttgattggca tctttatgag tctagcagct gtggccaagg
    33781 ttctccttgg gactgtgcta cttgtagcaa ttggttacta tatgcctgcc ctgctatttt
    33841 ttgtaggaat tgggatgtgg catttcttta tcagtgatat gttggaacct gtctatgaaa
    33901 tcatccatga aaaattggcg acaaaataga atgaagcagt tttggctaca tacgcttcta
    33961 agaacctata gttcagtgat gatcattatc attgcgagtt ttgcaatctt actctcttac
    34021 gctgactggg attcacgtga aaaggaagcc cagagagtag cccagcgtgt aactgctaga
    34081 acagtgagtg aaattgaata ttaccataga gagtcaaccc agatagctca ggctttagtt
    34141 gaaaatcaag ctcgtattga gggaatctat aaatacttta gccttagcat gccagactat
    34201 ttttactggc aattagagcg gaaagcttcg ccttatatat cagtctctct gtatgaaaat
    34261 gttgatgacc tctatgttcg aaatgatttt gtaactgggg tggccattgc ttttcaagat
    34321 tacaaggaag tctatgtttc tactaaagac aaacgtagtg gagaaaaaat cagggctgag
    34381 gatttcaaac cagcaggaaa tagttttgcc attccggtgt cagatccagt gtcagatcaa
    34441 gatttaggag tgatttacat ctccttggat cctgctgttt tataccatgc cattgataat
    34501 actagaggtc atactccgat ggcagtaaca gtgacctcac cttttgatac ggagattttt
    34561 catattggtg agacagttga tagggagagt gaaaattggc tagttggctt aacttctcat
    34621 ggatatcagg ttcaggtggc agttcctaaa aactttgttt tacaaggaac agtgactagc
    34681 tctgctttga ttgtgggttt gagccttctc tttattgtca ttctttatct gactttgagg
    34741 cagacttttg ctaattacca aaagcaggta gtggatttag tggaatccat tcaagtcatt
    34801 gctcaaggcg aagaggggcg tcggattgac atttccgaaa aagatcagga attactccta
    34861 atcgcggaga cgaccaatga tatgttggat cgattggaaa agaatatcca tgatatttac
    34921 cagttagagc ttagtcaaaa agatgccaat atgcgagcct tgcaggcgca aatcaatcct
    34981 cattttatgt ataatacgct ggagttcttg cgcatgtatg cagttatgca gagtcaagat
    35041 gagttggcag atatcattta tgaattcagt agtctcttgc gtaacaatat ttccgacgaa
    35101 agagagaccc tcctcaaaca ggaattagaa ttttgccgta aatacagcta tctctgcatg
    35161 gttcgctatc ccaagtccat tgcctatggt ttcaagatag atccagagtt agagaatatg
    35221 aagattccca agtttacctt gcaaccgctg gtagaaaact atttcgcgca tggtgttgac
    35281 cacaggcgga cagataatgt gattagcatc aaggctctta aacaggatgg ttttgtggaa
    35341 attttggtgg tcgataatgg tagaggaatg tcggctgaaa agttggcaaa tatccgagaa
    35401 aaattaagtc agaaatattt tgaacaccga gccagctaca gtgatcaaag gcagtctatc
    35461 gggattgtca atgtacacga gcgttttgtg ctctattttg gagaccgcta tgccattacg
    35521 atagagtctg cagagcaagc cggtgttcag tatcgtatta caattcaaga tgagtagaaa
    35581 gggagaaaat gtataaagta ttattagtag atgatgagta catggtgaca gaaggtctga
    35641 agcgtttgat tccctttgat aagtgggata tggaggtcgt cgcaacagcc agtcatgccg
    35701 atgaagctct agaatatgtt caggaaaatc ctgtcgatgt catcatttcc gatgtcaata
    35761 tgccagacaa aacagggctt gatatgattc gggagatgaa agagatctta ccagatgctg
    35821 cctatatcct gctctcaggt tatcaggagt ttgattatgt aaaaagagca atgaacctta
    35881 gtgtggtgga ctatttggtc aagcctgttg ataaggtaga gctgggaaat ctgctggaga
    35941 agattgcagg tcagctcggc gagagaggga agaaaagtca gactcttagt caagaattag
    36001 acgaggctgg atttgttagt tatttagggg ataaggagaa ttggtggata ggtctatcca
    36061 aggaaaaaca aggttccttc accattccct actatgtctt gggccaagac tggcagattt
    36121 tcatttctga ccaaccccta gatggtttag tcgttacacc ttttgaagct ccttatcaag
    36181 aacactttga acgctggaag ctgaatgctg agaaaaccct cttttacggt tctgtaaatt
    36241 tgcagcagtc tgagagtctc tttgcctatt acgaaccgat ttatagggtt atcattcagg
    36301 gaaatctcaa tcaaatcgta gaagagttaa atctcttgga gaaggtagtt cttgaaaata
    36361 cgccgcgtgt tccgattact aaacagcttt ttattcagtt tgtcatggat gttttccatt
    36421 tatttgaaca tctcaaagct gatgacctga cagacatcgt caaaaccatt catgctattc
    36481 aatccttcga tgaattggtt ccttatatca aggaaactct gagcagcttt ttcggtcaat
    36541 accgtatgaa tgaaaatgtg gtcagtgtgc tggaagtcat tggttgtgat taccaaaaag
    36601 agctttccct caaggatatc agtaaggctc tctttatcaa tcctgtctat ctagggcagt
    36661 tgattaagcg tgaaaccgat tcgacttttg cagagttact aaacaaacaa cgtattaagg
    36721 ctgcccaaca acttttgctt tcaactagtg acagcatcga agatatttgt tatgctgttg
    36781 gttacagtaa ccttggatat ttctataaag ttttccgaaa attgtgcgga aaatcgccaa
    36841 aagcctaccg aaaacaggta gaaactatac tataagattt gtattccttt acaaaatgtg
    36901 ctataatata aatattatta ttaggaggtt ctatcatgaa aaagaaacca atttatctat
    36961 gggtcttgct aatcttgtct gcccttattt cagttccgtc tctgtttgga attgtgagtc
    37021 ccttgcctag taaagaagcc cttcgtactg ctcagaaaca agttgcaggg gtcaatgctc
    37081 agcaattaga agaccagctt aattatacct atagagtagc agaagcatct cattctattt
    37141 ttaatgttgc tttgattgtg ctatctacta ttttagtggt cgtagcgatt gtcttccttg
    37201 ttcgtaaaaa tttgcaatat gcaaactata cttacgttgg ctatgttttg ttagctatta
    37261 ttggttcgat ttatggctat gttggtttac aagacgctgt gcagttggtt caagatgaga
    37321 gcatgcgttt gacagtgagt attggttcaa aagctgttag cattttctat atcgtcatca
    37381 atgttctctt cctagccctt gtcttctata agatgtggcg acaacagaaa gcctcggcag
    37441 aagaagagga aacagaagag cttgcctaag tattgacaaa aaagaactat caagatacaa
    37501 tcttggtagt tgttttttga ttatagataa aatcatggag gtacatatga agataatttc
    37561 tttagtttat attagtttga gtggcaacac tgaaagtttt gtgacgcgct tgaaagacta
    37621 tctcttgtcc cagtacaaag ggattgaggt tcaaaagatt catatcaagg atttagtcaa
    37681 ggaaggcaaa aatttctatg aaatggacca tccctatgtc gcttttttgc cgacctatct
    37741 cgaaggtggg aatggcgtgg ataacggaga tgttgagatt ttgacgacac cggtgggaga
    37801 ttttattgcc tatggtaaca atgctagtaa gtgttttggt gtggttgggt caggaaatcg
    37861 taactttaat aaccaatact gcctaacagc caagcaatac agtcaacgct ttggctttcc
    37921 tgtattggct gactttgaaa tgcgaggcat gctggaagat atcaaacatg tcgcagctat
    37981 tatcgcagat ttgtatgagt tggaaaagga gaattaatac tcaatgaaaa tcaaagagca
    38041 aactaggaag ctagtcgcag gttgctcaaa gcacagcttt gaggttgcag atagagctga
    38101 cgtggtttga agagattctc gaatagtata aaattcttat aagaggtggt tgaagttgtt
    38161 caactgtttt ttgagtataa acagtcttta agaacgtaaa aaagcataag ttcaggtctt
    38221 caaaaccttg ttcttatgct ttttatcata gaaatatttg ctgaattttc tcttgaaatg
    38281 aaaccttatc ttcatctcgc gcttgtccct taccctgctt ttccgattgc gagtgcgtag
    38341 ataaagaaga tggcgaagcc aaagaggaaa atcaatcccg caatggcaag gtgtttgagc
    38401 caagaaggaa gatttttgtt ttcacgcgtt accaaggcgt aattcaaaag agcaaagaaa
    38461 ggtgttgtca ggaaagagcc aatcatggca aagcggagca tggttgaaac ctgaccagag
    38521 aagaacttga taatgacgat accgatgata gcagtgatgg tcatccagat gttcaaagat
    38581 ttacgattgt cctctttttg actgattagc agtcggagag attcctgatt aacgcgagaa
    38641 tagccatcga taacagttat aactgttcca aagatacaga ggaaggcaat aaaggtaatc
    38701 aagtaacggg accattcgcc aagaacagag gcatacatgc ccacgaattg agagatgtat
    38761 ttggctgaag cagcttcaac cgcctgccct gtaggatact gaatcagtgc tcccagtgcc
    38821 acaaagaaga cggctaggat agctgttcca atataaccag tgttaaagtc aaacagagcg
    38881 tcttctgtgt taaagttgac ggtctttctc ttttcagctg accaaagtga attgatggct
    38941 gaaatttcaa taggagccgg catccatcct aggagggaga cgatgaaggg cagagctgcc
    39001 atttgccaag gtgtcttctc gacaaaatca gaactgtatt ctggatgctt gaccgccgca
    39061 atgataactg ccagaacagt cgcaatggtt aaggcagaca taatccattt gaccatgccg
    39121 tctaaaagtt tgtagcctcc aaagagtagc atagcccaaa tgattgcaac gagaatgagg
    39181 gaccactgag taatgctaag tccaatcatt gggaaggcac tggcgatgat agctgagcac
    39241 agaatggcaa caccagccgt gttgaccata gccgaaaaga cattgaggat aaagaaaatc
    39301 cagagataga gttttccttt ttcggcataa ccttcaacca aagtctttcc agtatcagct
    39361 gtgtattcag caccaaaacg gaaaaatgga tatttaaaga cattggctaa gatgaccaag
    39421 agaagtagag accaaccgta agaaccgcca gcttgagttg aggatacaat gtgggaacct
    39481 ccaacagcgg cagttgccat taggattcca ggtcccattg cttttagctt gcttgcccag
    39541 gttgattgat ttaaggaaat agcttgcgac atgataaata ctcctttttg aattttcaga
    39601 ataatctgta tatgtaatct atattctaca aaaaattttg gaaaaatgca agaatatttt
    39661 gaaaaaagat agaaaattta caaagaaaat
//
LOCUS       DAVBEM010000014        38639 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVBEM010000014 DAVBEM010000000
VERSION     DAVBEM010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38639
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.014"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            186..632
                     /gene="rplM"
                     /locus_tag="VQ548_000754"
     CDS             186..632
                     /gene="rplM"
                     /locus_tag="VQ548_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HET2653637.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            652..1044
                     /gene="rpsI"
                     /locus_tag="VQ548_000755"
     CDS             652..1044
                     /gene="rpsI"
                     /locus_tag="VQ548_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HET2653638.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            1393..1602
                     /locus_tag="VQ548_000756"
                     /pseudo
     CDS             1393..1602
                     /locus_tag="VQ548_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1758..2096
                     /locus_tag="VQ548_000757"
     CDS             1758..2096
                     /locus_tag="VQ548_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HET2653639.1"
                     /translation="MTLTIHVYYKGDGDCAIKFAREMLESGLVAEIRCQKGNLKYEYF
                     LPIEKEGIILLIDQWINQEALDEHHQSNTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            2286..3722
                     /locus_tag="VQ548_000758"
     CDS             2286..3722
                     /locus_tag="VQ548_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET2653640.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKKVILSNGESVE"
     gene            3774..4013
                     /locus_tag="VQ548_000759"
     CDS             3774..4013
                     /locus_tag="VQ548_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HET2653641.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            4143..4457
                     /locus_tag="VQ548_000760"
     CDS             4143..4457
                     /locus_tag="VQ548_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HET2653642.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            4575..6554
                     /locus_tag="VQ548_000761"
     CDS             4575..6554
                     /locus_tag="VQ548_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET2653643.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFAQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNSFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSYVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFISIFEKIK"
     gene            6564..6878
                     /locus_tag="VQ548_000762"
     CDS             6564..6878
                     /locus_tag="VQ548_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HET2653644.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            6909..7415
                     /locus_tag="VQ548_000763"
     CDS             6909..7415
                     /locus_tag="VQ548_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653645.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQILISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            7495..8841
                     /gene="celB"
                     /locus_tag="VQ548_000764"
     CDS             7495..8841
                     /gene="celB"
                     /locus_tag="VQ548_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HET2653646.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            9221..9397
                     /locus_tag="VQ548_000765"
     CDS             9221..9397
                     /locus_tag="VQ548_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653647.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            9807..12020
                     /locus_tag="VQ548_000766"
     CDS             9807..12020
                     /locus_tag="VQ548_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
                     /protein_id="HET2653648.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHFFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(12242..12718)
                     /locus_tag="VQ548_000767"
     CDS             complement(12242..12718)
                     /locus_tag="VQ548_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HET2653649.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            12941..16141
                     /locus_tag="VQ548_000768"
     CDS             12941..16141
                     /locus_tag="VQ548_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HET2653650.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSADASTRVIEAKDGA
                     ITISSHEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESDKDKRLWNSA
                     TTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQPSEDYQTD
                     KQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKEV
                     KKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSIS
                     SQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEW
                     MHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPE
                     HFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFY
                     QDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPL
                     LVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQS
                     DSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFG
                     LSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTET
                     DAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLG
                     SNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSK
                     KNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYML
                     IPNVGRATFNQMIKELERSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLK
                     RGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKNH
                     SDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            16521..16906
                     /gene="tnpA"
                     /locus_tag="VQ548_000769"
                     /pseudo
     CDS             16521..16906
                     /gene="tnpA"
                     /locus_tag="VQ548_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(17285..17914)
                     /locus_tag="VQ548_000770"
     CDS             complement(17285..17914)
                     /locus_tag="VQ548_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HET2653651.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(17924..18925)
                     /locus_tag="VQ548_000771"
     CDS             complement(17924..18925)
                     /locus_tag="VQ548_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HET2653652.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(18956..19597)
                     /locus_tag="VQ548_000772"
     CDS             complement(18956..19597)
                     /locus_tag="VQ548_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HET2653653.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(19616..20431)
                     /locus_tag="VQ548_000773"
     CDS             complement(19616..20431)
                     /locus_tag="VQ548_000773"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HET2653654.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            20702..21130
                     /locus_tag="VQ548_000774"
     CDS             20702..21130
                     /locus_tag="VQ548_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2653655.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPVKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEDFESGI"
     gene            21142..22332
                     /locus_tag="VQ548_000775"
     CDS             21142..22332
                     /locus_tag="VQ548_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HET2653656.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSAQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            22343..22834
                     /locus_tag="VQ548_000776"
     CDS             22343..22834
                     /locus_tag="VQ548_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET2653657.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLACNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            22849..23628
                     /locus_tag="VQ548_000777"
     CDS             22849..23628
                     /locus_tag="VQ548_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2653658.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTANHVVEEEAHDDWI"
     gene            23615..24433
                     /locus_tag="VQ548_000778"
     CDS             23615..24433
                     /locus_tag="VQ548_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2653659.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVVIGIIGSWLKIIA"
     gene            24433..24726
                     /locus_tag="VQ548_000779"
     CDS             24433..24726
                     /locus_tag="VQ548_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET2653660.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQTEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            24748..26649
                     /locus_tag="VQ548_000780"
     CDS             24748..26649
                     /locus_tag="VQ548_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HET2653661.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDMLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSNKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            26709..27710
                     /locus_tag="VQ548_000781"
     CDS             26709..27710
                     /locus_tag="VQ548_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2653662.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(27820..28155)
                     /locus_tag="VQ548_000782"
     CDS             complement(27820..28155)
                     /locus_tag="VQ548_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653663.1"
                     /translation="MKSLARLLNIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(28166..28408)
                     /locus_tag="VQ548_000783"
     CDS             complement(28166..28408)
                     /locus_tag="VQ548_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653664.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(28419..28961)
                     /locus_tag="VQ548_000784"
     CDS             complement(28419..28961)
                     /locus_tag="VQ548_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HET2653665.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(28977..29171)
                     /locus_tag="VQ548_000785"
     CDS             complement(28977..29171)
                     /locus_tag="VQ548_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2653666.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            29337..30287
                     /gene="rsmH"
                     /locus_tag="VQ548_000786"
     CDS             29337..30287
                     /gene="rsmH"
                     /locus_tag="VQ548_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HET2653667.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            30299..30616
                     /gene="ftsL"
                     /locus_tag="VQ548_000787"
     CDS             30299..30616
                     /gene="ftsL"
                     /locus_tag="VQ548_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HET2653668.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            30620..32872
                     /gene="pbpX"
                     /locus_tag="VQ548_000788"
     CDS             30620..32872
                     /gene="pbpX"
                     /locus_tag="VQ548_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HET2653669.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDSFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAVYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            32874..33854
                     /locus_tag="VQ548_000789"
     CDS             32874..33854
                     /locus_tag="VQ548_000789"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HET2653670.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNMGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLSFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            34463..36568
                     /locus_tag="VQ548_000790"
     CDS             34463..36568
                     /locus_tag="VQ548_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2653671.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQEKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVVIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            37291..38310
                     /locus_tag="VQ548_000791"
     CDS             37291..38310
                     /locus_tag="VQ548_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic biosynthesis protein"
                     /protein_id="HET2653672.1"
                     /translation="MSNTLKQLLLFREEFIKNILNGIDVDETVVIENDFVEELENFLK
                     ENDLLDFSNSIFFQLSGDKVIVNNIYPGYLAYFNRFLTFYPKIFAIKEVGEYIDFLNF
                     EKRIADMFYCWGFNANSRVLTAEKIIEIPNHQINAKYIKKVIKMSELLFGVDSNNRIR
                     LLNNRRELIKTIFQGSVIKSAIPALAATLDTISNSGSFQISLSKQIINNLVLSGKDKV
                     TIPRIELDNVVLSRQKIIVSVSYINDFLDLRFPDKIEYILNFLEGSGFNTKVMVYFGK
                     IVEEDKNYFVNLEKPQYFDFTSILFNKLFFKELNKFDYMVIEELIPNLDEDVMMTEYI
                     KEYTE"
     gene            38323..>38639
                     /locus_tag="VQ548_000792"
     CDS             38323..>38639
                     /locus_tag="VQ548_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653673.1"
                     /translation="MILSKVRCYIYNSKIRGKVLYELYEFINENKQLMDAINSIKVDS
                     SNGFSIQILHLGEQQTTVLLTDFFTKTLDLFKEFRVTNKSTLEQVKNQISILNSSGPK
                     MDLT"
BASE COUNT        12300 a         6338 c         8241 g        11760 t
ORIGIN      
        1 agttactttg agaagttacc gaaaaatatt tttcatatct attgactttt aggggtgaaa
       61 tttggtatga tagtaggcgg tattgtttac cccatttgaa aggccccgga accttccaaa
      121 tacttttcga tgggaaggaa cacccatcac cgtaaacaaa aatcgaacta tatataggag
      181 aaatcatgaa caaaacaaca tttatggcta aaccaggcca agttgaacgt aaatggtacg
      241 tagttgacgc aactgatgta ccacttggac gtctttctgc agtagttgct agcgtacttc
      301 gcggaaaaaa caaaccaaca tttacaccac acactgatac aggtgacttc gtgattgtta
      361 tcaatgctga aaaagttaaa ttgactggta aaaaagcaac tgataaaatc tactacactc
      421 actcaaacca cccaggtgga ttgaaacaaa tctctgcagg tgaacttcgt tctaaaaatg
      481 cagtacgttt gattgagaaa tcagttaaag gtatgcttcc acacaataca cttggacgcg
      541 ctcaaggtat gaagttgaaa gtatttgttg gagctgagca cactcatgct gcacaacaac
      601 cagaagttct tgacatttca ggacttatct aaggaaagga acaaataaag tatgtcacaa
      661 gcacaatatg caggtactgg acgtcgtaaa aacgctgttg cacgcgttcg ccttgttcca
      721 ggaactggta aaatcactgt taacaaaaaa gatgttgaag agtacatccc acatgctgac
      781 cttcgtcttg tcatcaacca accattcgca gttacttcaa ctgtaggttc atacgacgtt
      841 ttcgttaacg ttgtaggtgg tggatacgct ggtcaatcag gagctatccg tcacggtatc
      901 gctcgtgccc ttcttcaagt agacccagac ttccgcgatt cattgaaacg cgcaggactt
      961 cttacacgtg actcacgtaa agttgaacgt aagaaaccag gtcttaagaa agctcgtaaa
     1021 gcatcacaat ttagtaaacg ttaattcgaa agaattacta tacttataca gagcaccttt
     1081 cggggtgttc tttttttata ctttcttact aaattggtgc aattgacaca gttgttgcga
     1141 ctttagttgc ttacaaatgt ggctgcaacc tgacaaggtc agttgcctca aaacgctaat
     1201 caatacaatt atatcaatgt ttcaaagcac tcaaaggttt gccctatggg tgcttttttc
     1261 gtgttttttt gaaaagttta ccttattttt atagtaaggt gaaataagaa taggacaaac
     1321 cgaggatagt caaatcgaat tctaacaatg ttttagaagt agaggtgtac tattctagtt
     1381 tcaatctact atattatgga taatgcaaga ttccatagaa tgggtaagtt agaactcttg
     1441 tgtgaagagt ttgggtataa acttttacct cttcctccct actcacctga gtacaatcct
     1501 attgagaaaa catgggctca tatcaaaaag cacctcaaaa aggtattacc aagttgcaat
     1561 accttttatg aggctctttt gtcttgttct tgtttcaatt gactataaat cgctataaga
     1621 aaaaatcatt ttattggtat aaagaagtga ttgaaagtaa tggcgaaacg ttagataatt
     1681 agttcataaa aaacaagttt agatcctcat ctaaacttgt ttttttaaaa ttgaaggatg
     1741 attttggagg atatgagatg acattgacta ttcatgtata ttataaaggc gatggagatt
     1801 gtgcaataaa gtttgcaaga gaaatgcttg aatctgggct tgtcgcagaa attagatgtc
     1861 aaaaaggtaa tttgaaatac gaatattttt taccaattga aaaagaggga attattctcc
     1921 ttattgatca gtggataaat caagaagctt tagatgaaca tcatcaatca aatacaatgc
     1981 agaaaatctt agatttaaga aaaaaatatc acttgcagat gcaagttgaa cgttatatag
     2041 aagatgattc tgggatgcca gaaagcgata agtcgtttat agacacaggg aattagaatt
     2101 attgtgagag tttttgtagt ttgaaagtat tgaaaatcgt aaagatatca ttacgagaat
     2161 acaagaagat attgttctat ttccattaaa aattacttct ttccttaata ataaggaaaa
     2221 agaatacgtt ttcatctttt ggtttgaggt ttataataag aatatcaaag tcaggaggaa
     2281 aaaagatgac tacttttaaa gatggatttt tatggggtgg tgctgttgct gctcatcaac
     2341 ttgaaggcgg atggcaagaa ggtggcaaag gaattagtgt tgctgatgtt atgactgctg
     2401 gtcgccatgg agtagctcgt gaaattactt tgggagtttt agagggtaaa tattatccaa
     2461 atcatgaggc gatagatttt tatcatcgtt ataaagaaga catagcactt tttgctgaaa
     2521 tgggattcaa gtgcttccgt acctctattg catggacacg tatctttcca aaaggtgatg
     2581 agttagagcc gaatgaagaa ggattacagt tttatgataa tctttttgat gaatgcttaa
     2641 agaatggtat tgaacctgtc atcactctat ctcattttga aatgccttat cacttagtga
     2701 ccgaatatgg tggttggaaa aataggaaat tgattgattt ctttgctcgt tttgcagaag
     2761 tcgtatttaa acgttacaaa gataaggtta aatattggat gactttcaat gaaatcaata
     2821 atcaagcgaa ttatcaggaa gattttgcac catttactaa ctcaggtatt gtatatgagg
     2881 aaggtgataa tagagaagca attatgtatc aagcagcaca ttacgaatta gttgcttctg
     2941 cacgagctgt aaaaattggt catgagatta atccagattt tcaaataggt tgtatgattg
     3001 cgatgtgtcc aatttatcca gttacttgca atcctaagga tatcttaatg gcaatgaaag
     3061 ctatgcagaa gcgttattat tttgctgatg tgcatgtttt aggtaaatat cctgagcata
     3121 ttttcaagta ttgggaacga aaaggtattt cagttgattt tactgaccag gataaagaag
     3181 atttacttgg tgggactgta gattacattg gtttcagtta ctatatgtcc tttgctatag
     3241 actctcatcg tgaaaataat ccttattttg attatcttga aacagaagat ttagtgaaaa
     3301 ataattatgt taaggcttct gaatgggagt ggcaaattga tccagaaggt ttacgttatg
     3361 cgttaaattg gtttacagac cactatcact taccactctt tattgttgaa aatggttttg
     3421 gagctataga tcaagttgca gcagatggta tggtacatga tgattataga attgaatatc
     3481 taggtgccca tattcgtgaa atgaaaaagg ctgtagttga agatggtgtt gatttaatgg
     3541 gttatactcc atggggatgt attgatttgg tttcagctgg taccggtgaa atgcggaaac
     3601 gttatggctt tatttatgta gataaagatg acaatgggaa gggaagttat aatcgttccc
     3661 cgaaaaaatc ttttggctgg tataagaaag ttattttatc taacggtgaa tcagtagaat
     3721 agtataaaca aactgagatt attctcagtt tgtttagcat attgaggaga catatgattg
     3781 gaagtattgc agcaatttta acaacatttg catttttacc acaagttttt cgtgtagtta
     3841 agacaaagga cacaggatct attgctctag gtatgtatgt tatgcaagtt attggtattg
     3901 cattgtggct tgctcatggt attcgtatag gagacttgcc tttgatttta gcaaatagtg
     3961 tttcatttct actctcagga ataattttat tttataaatt gaagtataaa taattttttt
     4021 ccatatcatt taggaaaatg agggaattgt cattgaaaac gctttatttt ataataaaaa
     4081 tagataacaa ataagccaac ttagcacagc tttgattgga tttaagaaaa ggagaaaata
     4141 ttatggcaaa agctttaatt atttgtgcag caggaatgtc ttcatcactt atggcacaga
     4201 aaacaacaga gtttctaaaa ggaaaaggga aagatattgt agttgatgct attagtgcta
     4261 ctgaaggagg gaaagctatc gcagcagcag cttttgattt gtatcttgtc agtcctcaaa
     4321 caaaaatgta ctttaagcaa tttgaagagg ctggttctaa agcaggaaaa ccagttgtac
     4381 aaatacctcc tcaagcctat attcctattc caatgggaat tgaaaaaatg gctaatttga
     4441 ttcttgagaa tatttgatga acacatgaaa tgtcaataaa tatttaagtt aagataaatt
     4501 gttttgagtt tgatataaat tgatttaagt gtataatatg cttcaatata tgaaaacata
     4561 cgttttagga gggaatgaat gtgttaaaca ttaaagagaa agatatcctt caatttttaa
     4621 taaaaaataa ggaacgtttt gttacaagca aagaactggc agaatattta tcctgttcag
     4681 atagaactgt ccgtaatgta ctgaaattaa ttgagaagac aatgattatt caaggagtcc
     4741 ggttgatttc aaaacaaggt caagggtatc aaatattttt tgagaatcaa ggcgcttacc
     4801 aggagtttag acaaacttat gaactggaag aagactatac gaaaactgcg gtttcaaaag
     4861 gtgatgatcg tttagtattt atcttaaata aattattatt tgagcaagtt ccagttcttt
     4921 ttgatgattt agctgatgaa ctttacgtta gtcgttcaac attatctcat gatttcagaa
     4981 agatacgagt gatgttatca gagtataatt tgtccattga gagtagggcg aataaaggag
     5041 tttatgtctc aggcgaggaa cgtgataaac gacgttttat cataaattat ttcctagaga
     5101 atcaattttt taaaacaata cattgctatg taaaatttaa cttttttgct caaactgttc
     5161 cattagaaga atttgctaga attgttttgg atgaatgcca agaggccaac ctaaaactat
     5221 ctgattttgt actacagaat ttagtagttc acatagcatt gtctgtgatt cgtttaaaat
     5281 ccggatttga aataaaaaat atagactgtc agatgactga tgatgcaata gagagaaagg
     5341 ttgctcaaag aattctttct aaagtaagag aagtaacaaa tcaggaattt ccagttcagg
     5401 aaatagacta cattactttg catttgttag ctaagagtca acaatgtcaa aaaaatcaga
     5461 agaatatttc tgaagaagtt ttaaaaaaat ctttatttaa aacatttcag aatttaggat
     5521 tagatgatat gtataacttt tcttcagatt tccaactaat tgaaggattg ataactcatc
     5581 taatgacact acaagtacgt ttagaaagcc ggattacctt aaataaccct ttggtagatg
     5641 aaattaaaca gaattatagt gatatattct ttatgactag agaaattctt gcaaatatgg
     5701 acaagttctt ggagtggaca atatcagatg atgaagtagc atatgtaagt cttcactttt
     5761 tagctgctat ggaacgtagc aaagagagta ctaagtttaa tattcttgct atttgtgcaa
     5821 caggatttgg tgcagcccaa atgttaagaa atcgtttgga aacggagttt gggaagcgag
     5881 tagaagttgt tgatgtaata ggctattatg aattgaatca agaaaaactt aaaggaatag
     5941 attttatagt gtcagctgtt gatttatcaa atctatattt tcaaattcca gtttttaaag
     6001 ttagtgtgtt tcttaagagt gatgagatgg aaatgattag aaaagctatg gatcagatgc
     6061 aagtttctag ttatgtacaa tcatcaaaga ttaataaatt tgaaaacaac agctttagac
     6121 agtattttag taaagaaaat tttttaatat gtactgaatc agacaaggta aatttacttg
     6181 aaaagatggt tgagagttta tctgttggtg aatcaaatga gtttgaacaa tctttacttt
     6241 atggaattaa acagcgcgaa gaattaagtt cagttgtttt ttctgaaaaa attgcagttc
     6301 cgcatcctat tcagcccttt ggtacagagg gaaaggtttc ggttgcaatc tgtaaagatt
     6361 cgttactctg ggataatcaa agttcatatg tccagctagt atttcttcta tctccatcaa
     6421 tatatgggaa cgaaggtttg gcaactgtga ctaaaaagat agtctctctg acagagaatg
     6481 atgagttgca aaatcagcta atatcttgca ataactttga agattttatt agcatatttg
     6541 agaagataaa ataggaggtt catatgaatc aagaggaact gcaggttgca gcatttgaaa
     6601 ttatcctgca ttcgggaaat gcaaggtcag aaatacatga agcatttgca aaaatgagag
     6661 aaggtagttt tgatgatgca gaaagtaaat taaatcaatc aaatgagata attcttgaag
     6721 cgcatcatgc acaaaccaaa ctcttgcaag aatacgcaag tggagtggaa attaaaattg
     6781 aaattatcat ggtacatgct caagatcatt taatgaccac tatgacatta ttagaagtag
     6841 caaaggaaat gttagctctt tataagaaag ttaactaaat atgtgttgtt atataaggag
     6901 gaaatgatat ggataaaaaa gaacgacaaa agattgaaca acaacgtcga gagatggctc
     6961 taactaatac tttttttaat cgatatcttc ttctacgtta ttcaatagca ctcttctttt
     7021 ttgggaatat ttattggctt ttgaatcagt ttattaatcc ctcgcctatt attattttcc
     7081 ccattatgct catagtattt tctattttag caactgttga acaatttaaa ctctatggaa
     7141 ataggaaaga aaagttggga ataacactaa tgtttgttag aatacaaata cttatttcaa
     7201 taggattact tgttttaact tggacaagtt ggtttaagaa tctttttccg atttttgaaa
     7261 ataaccaagt agcacgttta tttgtttttg tagttcttct attaggttta gttctgagtt
     7321 tgttagacat tagaagaatt aaaaaaattt ataaacgaac agataaggct tatcaacaat
     7381 ttgtccaatt ggaaaagaac tcacttagtt tataatcctg atctagtata atttgtattt
     7441 gaaactagtc tttagaaagt aaaaattatt atgttttatt aaggaggtct atttatggat
     7501 caacaaaacg ggttgtttgg ttttcttgaa aaccatgtta tgggaccaat gggcaaactt
     7561 gctcagttta aagtagtgcg tgctatcacg gctgcaggta tggctgctgt accatttact
     7621 attgtaggat caatgttttt ggtattcagt attttgccac aagctttctc attttggcca
     7681 attgtggcag atattttctc tgcttcattt gataaattca catcacttta catggttgca
     7741 aactatgcga ctatgggttc tctatctctt tatttcgttc tatcacttgc atatgaattg
     7801 acaaaaattt atgcagagga agaagaactc aatatgaatc ctcttaatgg tgccttgctc
     7861 gccttgatgg cttttgtcat gacagtaccg caaatcattt ttgatggtgg aatgatgaag
     7921 actgtgacaa gtctaaaaga aggtgcagta attgcagatg gatgggcaat gggaaatgga
     7981 gtcgcacgtt ttgggacaac agggattttt accgcaatca ttatggcaat tgtgactgtt
     8041 cttatttatc gtatgtgtgt taaacataat tgggttatta aaatgcctga agctgttcca
     8101 gaaggagttt ctcgtggatt taccgctttg gttccgggat ttgttgttgc atttgttgtt
     8161 atctttatca acggtcttct tgtagcaatg ggaacagata tttttaaagt cattgcaatt
     8221 ccatttggtt ttgtatccaa tctgactaat tcgtggattg gtttaatgat tatttatcta
     8281 ttgactcaac tactttggat tgtaggtatc cacggtgcga acattgtttt tgcatttgtt
     8341 agtccaattg ctcttgctaa catggctgaa aatgctgctg gcgggcactt cgctgttgca
     8401 ggtgaatttt ctaatatgtt tgtaattgca ggtggttctg gtgcaacttt aggactatgt
     8461 ttatatattg cttttgcctc taaatctgaa cagcttaaag caataggacg agcatctgta
     8521 gttccagcct tatttaatat taatgaacca ttaatttttg gattacctat tatctataat
     8581 ccagccttgg ctataccatt tattttagca ccaatggtta ctgctactat ttattacgta
     8641 gcgaattctc taaactttat taagccaatt atcgcacagg ttccatggcc aactccagta
     8701 gggattggag ctttcttagg gacagcagat cttcgagctg tattagttgc tctagtatgt
     8761 gcatttgcag cattcttagt ctatcttcca ttcatccgtg tatatgatca aaaattggtg
     8821 aaagaagagc aaggtatcta ataagtaaaa aagtatactc gatgatagaa tccatatagt
     8881 ttaaataatg agtgttaata ttagcagtga agaggtcttt ttaagatatt cttctctgct
     8941 ttttcatatt ttttcgctat gtagggtatg aagcaaaata gaaagtagtt cgaatagttg
     9001 ataaacagga aactgctgtt atttaaaaaa aacaataaag taaagtatgt tatcgtagaa
     9061 tacgatacaa tagtaaaaaa gcaaaaagaa tgcgttttat atttgggttt gaggtttata
     9121 aaataggata agcgtgctga aaacttagat atgacaaaca aaataaaatt tttaaaagct
     9181 acatagaaac atggtataat gtatctaaag gaggtagcat atgtccttag atatagataa
     9241 agaaaagatg acaatcatgg gaatagcttt tgaaaacaga tccgttttta agagtgtttg
     9301 gtatgcttta agtacaaata tgattgaagg atggcgacct acggttagtg atgttgaaaa
     9361 attacgagat gaagctcttg ctctggggat gacttaatga agcgcaactg ttatgagtct
     9421 tatgactatg ttgatccgga taatttatat accgatccgg gttcttcagt tctaagaaat
     9481 aagcaggaag gaaaaaagca cgcgagcttg aatatcgtat gattgctagt aagagtttga
     9541 aattatttat caatcctatc ttagttaata gtttaaaagt agtttgtttc acaactgcat
     9601 aagcttagaa aagttgaaaa gtgataactc tttaataaac tcttggtttg ttaaaagata
     9661 ttttgtccac tacatttttt caattgacta ttatttgtca tagatataac agatagaaca
     9721 gatagaacat tgcattcaga ataatgaaaa acgcatcaaa aatggtgcgt tctgttttta
     9781 tgctaccata aaaggaggaa aacaaattga aaatttttaa gggagagttt tatcgaatct
     9841 ctgtattaac agacaagcta gtaaggttag aatactctca aactggaagt tttgaggata
     9901 gaacgacaca acttatctat aatagagatt ttggccaagt ttcgttagat tatatcgaga
     9961 catcaaacgt actagatatt atgacggact attttcatct gcactttaat aaaggagaat
    10021 ttaacgccga aaatttattt atagaattaa aaggaaattt tgccgtatat ggtagtcgct
    10081 ggtattttgg tgaatctatt gaaacgttaa aaggaacagc tcggactctg gataaggcag
    10141 atggagcaat ctcgttagaa gatggaatta ttagccgaaa tggtatagcc ttattggatg
    10201 attctcaagg atttatttgg gatgaacaat ctggttatat tgagagagaa aatcaaattg
    10261 acctgtattt ctttgcctat gggcatgatt atagaggagc aatcagagac ttttaccatt
    10321 tgactggttc aacacccttg ttgccaagat atgctttagg caattggtgg agtagatatt
    10381 ggccttatac gtcggatgaa tacttggatt taatagacag atttgaaaca gagaaaattc
    10441 cattatctat cggtgtgtta gatatggatt ggcatataac tgacattcca gctcgttttg
    10501 gaagtggctg gacaggatat agttggaata gaaacttaat accaaatcca gaacagttat
    10561 tgcaacaact tcatgataga aagttaaaac tctccttaaa tgtccatcct gctgatggga
    10621 tacgggctta tgaagaagct tatcctcaaa tcgcaaaacg gttggggtta aatgtagaac
    10681 tagaagaacc tgctattttt gattttttta atccctcttt tagggaagcc tactttaaag
    10741 atgttcatta tgagctagaa aagcagggag tagatttttg gtggattgac tggcaacaag
    10801 ggacacaagg tatgctagat ccactttggc ttttaaacca ttatcactat caggatagtt
    10861 gtaaaaatgc agaaggtggt ttgattttat caagatatgc aggtcctggt agtcaccgct
    10921 accctgttgg tttttcaggg gatactatta ttagttggaa ttccttaagg tttcaaccct
    10981 attttacagc gacagcatct aatatcggtt atagttggtg gagtcatgat atcggtggac
    11041 atatgttggg ggattatgac gaagagctac aaactagatg gctacagttt ggtgttttta
    11101 gtccgattac tcgattacat agttctagaa gtccttttaa tagtaaagaa ccttggttct
    11161 tttcagaaac aacatctaag attatgaaga aataccttcg tttgagacat cagatgattc
    11221 cctatctata taccatgaat gtaaagacac atgaggaagg tgccccatta atcagtccaa
    11281 tctattattt ctatccagag aatgatgaga gctataatgt tccaaaccaa tacttttttg
    11341 gaacagaact gatggtggct cccattgtag aaaagatgga tttgacattc caatctgcaa
    11401 aagtagatgt atggttccct gaaggtgaat ggtatgactt cttttcagag aaaaaataca
    11461 caggtggtgt gaagttaagt gtttataggg acatctcgac tacgcctgtg tttgcaaaaa
    11521 gtggtgcaat cattcccttg gttggttctg agataggtat gggtgttgat ttacctgagg
    11581 ttgtagattg gtatgtattc ccagggaaac aacatttttt tgaaatgctt gaagatcaaa
    11641 atggtcaaag atataaaaca agattatcaa tcgattggga aatgggaatg gtagagttag
    11701 cattacaagg agattctagt atcgttccaa gcaatagaaa acatagaatt cattttaaag
    11761 gaacgaatgt gtctataatt gaattgccaa ataagaatga tacagctaaa tttgaatgga
    11821 aagataataa aaggacatct ttaaatgacg aagtttttag actactaaag acagcttctc
    11881 ttccatatga attaaaagat agattgttaa atcaattcat caatgcgaaa aactctcatg
    11941 acttaatgaa tatcttgcat catcaggata aggaattgag agggcgtttg ttggaaatga
    12001 tatttactag ccaaaactaa ttgaaataat tagaaagtca tttgtttagt gtatatgaag
    12061 attctgtatg gtattcgtta tcactggtca cattgaaaat gtgaaataag cacctacaac
    12121 atagacttta caacacttca tgtttcatat catggggtgt ttttctattt aagtcaaagc
    12181 ccatcaaaaa atctcactat tcatcaggtt aaaggaaacc taatcatagt gagattgtga
    12241 attatagtag agtttgtatc gcctcttcaa tttgttttgg gtctgttttt gaagaaaagc
    12301 gttcaaagac ttgcccatct cgaccgatga gaaacttagc gaaattccat tcgattcgtt
    12361 ttcctagtgg gccggatttc tggtctttta accagacata gagagggtct gcttccttac
    12421 cgttgacctt aatcttggca aaacgtggga aggtggtttg aaaatgtagg ctacagaagg
    12481 cgttgatttc ctctgcgctg ccgggtgctt gtcccataaa ctgattgcaa gggaaatcca
    12541 atatttcgaa gccctgatct tgatagcgtt catagagttc ttgaagtccc tggtactggg
    12601 gcgttaaacc acatccagta gcagtgttga caatcaagag aactttgcca cgatagctat
    12661 ccaagggagt tgcttggttg ttttggttca aaacggaaaa atcataaagt gaagtcatga
    12721 gggcctcttt tctttttcta cattgtaaca gtttttactt ttttcgtcga gtcggatgga
    12781 agatattgtt gaagaataag ccttcaatat gatagaaacc gtttacaaat aactttaaaa
    12841 atggtatgat ttaattaaac cggtttactt agttgctata aatctctaat ttgagattta
    12901 gttcctattg attttacaat atgtttattg gagtgtatac atgcaaacaa aaacaaagaa
    12961 gctcattgtg agtttgtctt cacttgtttt atcaggattt ttattaaacc attatatgac
    13021 agttggagcg gaagaaacga ctacgaatac cattcagcaa agccagaagg aagttcagta
    13081 tcagcaaagg gatacaaaaa atttagttga aaatggtgat tttggtcaga cggaggacgg
    13141 aagcagtccg tggacaggaa gcaaagctca ggggtggtca gcttgggtag accagaagaa
    13201 tagtgcagat gcctcaactc gagtcattga ggctaaggat ggggctatca ctatctcaag
    13261 ccatgagaaa ttaagggcag cggttcaccg tatggttcct attgaagcta agaaaaagta
    13321 taaactgcgt ttcaagatta aaacagatca taaagtcggg attgccaaag ttcgtatcat
    13381 tgaggaaagt gataaggaca agcgattgtg gaattctgca acgacgtcag gaacaaagga
    13441 ctggcagacc attgaagcag actatagccc gactttagat gttgataaaa tcaagctgga
    13501 gttattctat gaaacaggaa ctgggactgt ttcctttaag gatattgagc tggtagaggt
    13561 agcagaccag ccttctgagg actatcaaac agataaacag cttgaggaaa agattgattt
    13621 accaattgga aaaaaacatg ttttttctct tgcggactat acttataagg tagaaaatcc
    13681 tgacgttgct tcagtcaaaa atggaatttt agaacctctt aaggaaggga caaccaatgt
    13741 cattgtcagt aaagatggca aggaagtgaa aaagattcct ttgaagattc tagcctctgt
    13801 taaggatgca tacacagacc gtttggatga ctggaatggc atcatcgctg ggaatcaata
    13861 ctatgattct aaaaatgaac agatggccaa attaaaccag gaattggaag gaaaggtagc
    13921 tgatagccta tctagtattt caagtcaggc ggaccgcacc tatttgtggg aaaaattttc
    13981 aaattataaa atgtctgcaa atctgactgc cacttatcgg aaattggagg agatggccaa
    14041 gcaagtgacc aatccttctt ctcgttatta tcaagatgaa actgtcgttc gaacagtcag
    14101 ggattccatg gaatggatgc ataaacatgt ctacaatagt gaaaagagca ttgttgggaa
    14161 ctggtgggat tatgaaatcg gtacacctcg tgccatcaac aataccttgt ctctgatgaa
    14221 agaatacttc tctgatgagg aaattaaaaa atatacagat gtgattgaaa aatttgtacc
    14281 agatcccgaa catttccgaa agacgactga taacccattt aaggctctag gtggaaactt
    14341 agttgatatg ggaagagtaa aagtaatagc tggtttactg cgtaaggatg atcaagaaat
    14401 ttcttctacc attcgctcga ttgagcaagt gttcaagttg gtagaccaag gtgaaggttt
    14461 ttatcaagat ggatcctata tcgaccatac caatgttgcc tatacgggtg cttatgggaa
    14521 tgttttgatt gatggcctgt ctcaactgtt gccagtcatt caaaagacca agaatccaat
    14581 cgataaagat aaaatgcaaa ccatgtacca ctggattgat aaatcgtttg ctcctttgct
    14641 ggtgaatgga gagctgatgg atatgagtcg tggacgctcg atcagtcgtg caaatagcga
    14701 ggggcacgtg gccgcagtag aagtactaag agggattcac cgaatagcgg atatgtctga
    14761 aggagaaacc aaacaacgtt tgcagagtct tgtgaagacc attgttcaat cggatagtta
    14821 ttatgatgtc tttaagaatt tgaagactta taaggatatc agtttgatgc aatccttgtt
    14881 aagtgatgca ggagtcgcaa gtgttccaag aacaagttac ctatctgcct ttaacaagat
    14941 ggataaaaca gccatgtaca atgcagagaa agggtttgga tttggcttgt cactcttttc
    15001 cagtcgtacc ttgaattacg aacacatgaa caaggaaaat aaacgtggtt ggtatacgag
    15061 tgatgggatg ttctatcttt acaatggcga tttgagtcac tatagcgatg gctactggcc
    15121 aacagttaat ccatataaga tgcctggtac aacagagacg gatgctaaga gagcggatag
    15181 cgatacaggt aaagttttac cgtctgcttt cgttggaacg agcaaactag atgatgccaa
    15241 tgcgacagca accatggatt tcaccaactg gaatcaaaca ttgactgctc ataagagctg
    15301 gtttatgcta aaggataaga tcgccttttt aggaagcaat atccaaaaca cttcaacaga
    15361 tactgctgca actacaattg accagagaaa actggaatca agtaatccat ataaagtcta
    15421 tgtcaatgat aaagaagcct cccttacaga acaagaaaag gattatcctg aaacccaaag
    15481 tgtcttttta gaatcatccg attcgaaaaa gaatattggt tactttttct ttaagaagag
    15541 ttcaatcagt atgagtaagg ctttgcaaaa gggagcctgg aaggatatca atgaaggaca
    15601 gtcagacaag gaagttgaaa atgaatttct tacgattagt caggctcata agcaaaatgg
    15661 agattcttat ggctatatgc tcatccctaa cgtgggtcgt gccaccttca atcaaatgat
    15721 aaaagagtta gaaagaagcc tcatcgaaaa taacgaaacc cttcagtctg tttatgatgc
    15781 caaacaagga gtttggggca ttgtgaaata tgatgattct gtctctacta tttccaacca
    15841 attccaagtt ttgaaacgtg gagtctatac cattcgaaaa gaaggggatg aatataagat
    15901 tgcctactat aatcctgaaa cccaggaatc agctccagat caggaagtct ttaaaaagct
    15961 agagcaagca gctcagccac aagtacagaa ttcaaaagaa aaggaaaaat ctgaagagga
    16021 aaagaaccat tcggatcaaa agaatctccc tcagacagga gaaggtcagt caatcttggc
    16081 aagtctaggg ttcttgctac ttggggcgtt ttatttattc cgtagaggaa agaacaacta
    16141 atttgttcat catctagatg aattacatga aactgtggaa aatagaaaaa atccgaagaa
    16201 ggccaaatat cttcggattt ttcttttaaa aaaggataag ttgatactta tcctttttac
    16261 ttcattatgt gactatagcg ttttgaaact agaataggac atcataactg ctaaaagatt
    16321 tctataaatt catttgattt tcctaatcaa tttattcgta tcctatttca ctctactata
    16381 ttagtccgtc tcgcacctca cggagcgaga caaaacaacc acccgctatg cgggtgcgcg
    16441 tcgaaggtta taccaaaaaa actccaaacg cgatacaata aaggtgttca atccacttgt
    16501 aaagcgaaag gagaaaaaat atggcacaaa aggctcatag tttatctcac acaaagtgga
    16561 ggtgttctat cacattgtgt tcacccctaa gtatagacga aaagtcatct ataatcaata
    16621 tagaagtagt ttaggcgaaa tatttcatcg cttgtgtagt tataaaggtg ttgaaatgat
    16681 cgagggtcac ttaatgccag accatgtaca catgttagtc agtattccac taaggctaag
    16741 tgtttcgagt ttcatgggtt atttaaaagg aaaaagtgca ctcatgatgt ttgacaaaca
    16801 cgccaatctc aagtacaagt ttgggaatcg gcatttctgg gtggaaggtt attatgtaag
    16861 tccagtaggg cttaatgaag ccacaattaa gaaatatagt caagattaaa gaaattatcc
    16921 agtggatgat ttcttcacga gtatgaaaat ttgagaacta gtaaagtatg atatatagta
    16981 aaatgaaata agaacaggac aaaatcgatc aggacagtca aatcgatttt taacaatgtt
    17041 ttagaagtag aggtatacta ttccagtttc aatctactat agcactagat aaattgagtg
    17101 taaaagaata tgaggatccc tttagggata gtggtaagta ataccaaagt ctcttaaaga
    17161 ggcaagtgac gagtcaagag caataaggct tgaacaacgt aaaagccagc gtctttaggc
    17221 gctggctgat gatttgggct tatagctctg ggataaacca cccgttagac gggtagttat
    17281 gattttatct gagtgtaata tactgttggg caatctcgct gatgcggtca aagttgcctt
    17341 gggaagcgag tttattgagt tcgccaccaa ttccaacggc atctgcacca gcagcgaacc
    17401 attgagggat gttgtttagg ccgactcctc cggttaccat tacggaaact tgtgggatcg
    17461 gtgccttgac tgcagagata tatgctggac tgagagtact acctgggaag agtttgatga
    17521 tttcactacc ggcttcaagt gcagtcgtga tctctgtgag ggtaatacag cctggaatgt
    17581 acggtgtgct gtagagattg cacattttcg cagtttcagc atggaaagat ggagaaacaa
    17641 cgtaatttgc tccagctaga atggcatctc tagcagttac ggcatcaagc acagtacctg
    17701 caccgataca aacactctga tcgtcctgat acaagtctac aagttccttg atgatttgtc
    17761 ctgcatactg attggtatag gcgatttcaa tagctttgat accgcccttg atacaagcaa
    17821 tcgaggcttg tagtccttct tcctttgtat ttcctcgaat gacagcgaca attttctgtt
    17881 tttttagttc aataatcgta tctgatttgg tcatgtaatt ctcctaacga atgatatctt
    17941 gtgcatttgc cagtaaattt tcaatactag ttgcggaagt ggagagatgg tctcctggaa
    18001 gagtgcattt gagagttgcg ctcgcaactg caaagtcaat ggtagttttt agggaggaat
    18061 gatggagtag ttggtaaagg gcaccagata taaaggcatc cccgctacca attcgttgat
    18121 agactgcagt ttttagttgg acagactctt caaatcgttc ttccagagca taggcttgat
    18181 agacattttt gtcttgctca tcactagatc ggagggtatg gaaaatggcc ttgaaaccat
    18241 aggcttcttt taaaagtcgc atgcgatttt ccacctcttc taggctagca ctgtctcttg
    18301 gaaacatctc tagattttgg tcatcaatca tgagaggatc aataccgaag caatagtcag
    18361 taaaacgtgc aaacttagaa aattcatact tggcttctag gactgaaatc atctttgttc
    18421 tcagattgag atccattgaa acgacaattc ctcggcgctt ggcttcttcc aagagtagga
    18481 gaaggatcgc acggacctct tgaccgatag ctatggtgat tccactaaaa tgaaaatggc
    18541 taatcccctg aaagagagaa tccatatcta gcatgtttgg ccgaatctgg ctgatactcg
    18601 tatgcttacg atcgtagaaa acttcacttt gacgacaacc aaagccgttc tccaaatagt
    18661 agaggccgat tcgatcgcca agccgacaga ttgaactggt atcgatttgg tgctgtttca
    18721 agaatgtgag aaaacgatct ccaatctcgt tggcagggag tgcggtaaag actttcgttg
    18781 agatacccag ggcttgcaaa ttacaagcga tgttaatttc tgatccgcca aaataagtcg
    18841 aactggcaac atgatcgccg atactggtgg catctaatgg tgagattcga attaatggtt
    18901 cgccaaacag taatattttc gtcatccatt agttcctttc tggtttagaa tagctttact
    18961 tggctaatac ttctttcaaa taagcagcga cttcatcatc ttggcagttt tcaaagaagt
    19021 attcttggaa gtatttgcca gagatggtgt ctttgaggaa gtcttggtcg attgttttaa
    19081 ggatggtcat caaatcattg tgggtgattt gtttcacctc gtttaagata cgagcgttgc
    19141 gttgttcagg gattacacgt tctcttgggt agccaccgcc catttcttca gcaaataagc
    19201 gttcaaacat caatttgagg gtcagttctg ccccccagcc aaatcctttg gcataaggga
    19261 tagacaaggc gttaccacca ttgatttgag aataaaggta agcgtcagtt gggtccactg
    19321 ctagaccaca gacaacacca gggaagctgt ttaaagcaag catagcccct acacccgtac
    19381 cacagccggt aacaacaaag tcaactgcct ttgtatttaa aaggatggca gccattagtc
    19441 cgttctgcac ataagttaat tgactttctc cttcttctcc acgcatacca tagttaaata
    19501 attggtagtc ttttttatct gtcgcttctt ttagactatc gtaaataatg tgattcttgc
    19561 tagcttgact attttcattg attaatgcga ttttcataag atcttctttc tatttttact
    19621 caggttgttt tccgatgtag gctaagatac cgccatctac atataggatg tggccattga
    19681 caaaattgct ggcatcacta gcgagaaaga cagcagggcc catcaaatct tcaggatttc
    19741 cccaacgtgc agcaggtgtt tttgcaatga tgaactggtc aaatgggtgg cgagaaccat
    19801 cttcttgcaa ctcacgaaga ggtgctgttt gaggagtggc aatataaccc ggtccaattc
    19861 cgttacattg gatattggct ccaccgtatt cagacgcaat gttgcgggtc aacattttca
    19921 agcccccttt agcagcagca taagcgctaa ctgtttcacg tcccagttcg ctcatcatcg
    19981 aacaaatatt gataatcttt ccatgccctt tctttatcat agaaggaata actgcctttg
    20041 aaacgataaa tggtgcgttt aagtcaatat cgatgacctt acggaaatca gcggcgctca
    20101 tttcgcacat tggaactcgg cggataatac cagcgttatt aacgaggatg tcaatgacac
    20161 caacctcttg ttcgatttgc ttgaccatgg cttggatacc gtcctcgtct gtcacgtcac
    20221 agacatatcc atgggcttcg atgccaactt cacgataagc ttcaatccct ttattgacca
    20281 gatcttgatt gatatcgtta aagacaatag tagcgccggc ttcagcgtag gatttggcaa
    20341 tagcaaatcc aattccataa gaagcgccgg tgatgagagc aatttttcct tttaaagaaa
    20401 actgctcaat tgagaatgat gtatttgtca tttgatactt cctttcaaat ttgttaagac
    20461 ttctctataa ccaaattata ttctagcaaa ccggttttgt caataaataa atatttttat
    20521 ttataaaaag atttgttttc ctgaaaaacg gaatgttttg aaatttctgt ttattaaaat
    20581 ggttaaaaag ataatgaaag cgctaatatt tttttaaaaa aactattgac aagataaaaa
    20641 taaaggatta caatggggaa tataaagtaa accggtaaac ctaaacaaga aaggagaaaa
    20701 gatgaaaatt gtacttgtag ggcatggaca ttttgctaca gggatttata gttctttaca
    20761 attgattgca ggtaatcaag aaaatgtgga ggcgattgac tttgtggaag gaatgtcagc
    20821 agatgaactc aagcaaaaaa tcttacttgc aatttcaaat gaagaagaag ttttaatcct
    20881 aagtgatctc ttgggaggat cgccattcaa ggtttcttct accataatgg gagaaaatcc
    20941 agtcaaaaca atgaatgttc tctcgggttt gaacttagcc atgttaatgg aagcagtctt
    21001 tgctagaatg gctcatagct ttgatgaggt tgttaataaa tcagtagtgg cggcccaggg
    21061 cggagtcgta aatggtaaag aattgttttc aacggatgca gaggaagaag atttcgaatc
    21121 gggtatttaa agggtaaaag aatgataaaa aaggttacga ttgaaaaaat aaaatcgcct
    21181 gagcgcttct tagaagtacc acttctgacg aaagaagaag tcggccaggc aatcgataag
    21241 gttattcggc agttagaact caaccttgac tatttcaagg aagatttccc gacgccagct
    21301 acctttgata atgtctatcc aatcatggat aacacggaat ggaccaatgg tttctggaca
    21361 ggagaactgt ggttggctta tgaatacagt caacaggatg catttaaaaa catcgctcat
    21421 aaaaatgttc tttctttcct ggatcgtgtc aataagagag tagaattgga tcaccatgat
    21481 ctcggcttct tgtacacacc gtcttgtatg gctgaatata agataaatgg agatggagag
    21541 gctagagaag caaccttgaa agctgcagat aagttgattg aacgctatca agaaaaaggt
    21601 ggttttattc aagcttgggg agacttgggc aagaaagagc attaccgttt gattatcgac
    21661 tgcttgctca atatccaact cttattcttt gcttatcaag aaacaggcga tcaaaaatac
    21721 tacgatattg cagaaagtca tttctatgct tcagctaata atgtaatccg tgatgacgct
    21781 tcgtccttcc acaccttcta ttttgatcct gagacaggtc aaccctttaa aggtgtaacg
    21841 agacaagggt atagtgatga ttcatgctgg gcacgtggtc aatcatgggg agtctatggt
    21901 attcctttga cttatcgtca cttaaaagac gagtcctgct ttgacttgtt taagggtgtg
    21961 accaattatt tcttgaatcg tctgccaaaa gatcatgtgt cctattggga tttgattttt
    22021 aatgatggta gtgctcaatc acgagattct tcagcaacag ctatcgccgt ctgtgggatt
    22081 catgaaatgc taaaacatct cccagaggtg gatgctgaca aagatattta taaacatgct
    22141 atgcatgcca tgcttcgttc cttgatcgaa cattatgcaa atgatcaatt tacccctggt
    22201 gggacaagtc ttctccacgg tgtgtactca tggcattcag gtaaaggagt ggatgaaggc
    22261 aatatctggg gtgactacta ttacctagaa gcccttatcc gtttctacaa agactggaac
    22321 ctatattggt aggaggagaa atatgacaat gccaaatatt attatgaccc gtatcgatga
    22381 acggttgatt catggacaag gacaactttg ggtaaaatac ctagcttgta atacggtcat
    22441 tgttgccaat gacgaagtaa gcacggacaa gatgcaacaa actctgatga aaacagttgt
    22501 gccagactca gttgccatgc gtttcttccc tttgcaaaag gtgattgata tcattcacaa
    22561 ggctaatcct gctcaaacga tctttatcgt tgtaaaggat gtaaaggacg ctttaacctt
    22621 ggtagaaggt ggtgtcccta tcaaagaaat caatattggg aacattcaca atgcccctgg
    22681 taaagagcaa gtgacacgct ccatcttcct gggtgaagag gacaaggcag ccctcaagga
    22741 attaagccaa actcatcaag taacatttaa tacgaaaaca actccaacag gaaatgatgg
    22801 agctgttcaa gtcaacatta tggactatat ttaaaagagg agatcgttat gtcgattaat
    22861 gtatttcaag cgattttaat tggattatgg acagctttct gttttagtgg aatgctgtta
    22921 ggaatttaca ccaatagatg tattgttctg tcatttggtg tcggaattat tctaggtgat
    22981 ctgcctactg ctcttgcaat gggagctatt ggtgaattgg cttatatggg attcggtgtt
    23041 ggtgctggag gtactgttcc accaaaccca atcggacctg gtatctttgg taccttgatg
    23101 gctatcacta gtgctggtaa agtcagtcca gaagcggctc ttgccctctc tactccgatt
    23161 gctgtggcga ttcaattctt acaaactttc gcctacactg tacgtgctgg tgcgcctgaa
    23221 acggcgatga agcacttgaa aaaccataat ttgaagaaat tcaagtttac tctaaatgca
    23281 acaatttggt tgtttgcctt tattggattt accttgggtt gcttgggtgc cctttcaatg
    23341 gataccttgt tgaaactcgt agactacatt ccaccggtat tacttacagg tttgacagtt
    23401 gctggtaaaa tgctcccagc tatcggtttt gcgatgatct tgtcagtgat ggctaagaaa
    23461 gagttgattc cctttgtctt gttgggatat gtttgtgcag cttatctaaa catcccaaca
    23521 attggtattg caattgtagg tactatcttt gctttgattg aattttataa caagccaaaa
    23581 acagcgaatc atgtggtaga ggaggaagca cacgatgact ggatctaaca aattaacaaa
    23641 acgtgattat cttaaaacgt ctttgcgggc attcttttgt caaaatggat ttaactatag
    23701 taactatcaa gggttgggat atgccaatgt gatgtatcct gctttgaaaa aacactatgg
    23761 agaggatcag gaaggtttct accaagcctt ggaagaaaac tgtgaattct ataataccaa
    23821 cccacacttc ctgcctttta ttaccagctt gcatcttgta atgttggaaa atggccgtcc
    23881 ggcaaaagaa acacgtagca tcaagatggc cttgatggga ccattggcag gtattgggga
    23941 ttctctttct caattctgtt tagctccatt gttctcaacc atcgcagctt cgtttgctca
    24001 agaaggcttg gttgtcggtc caatcttgtt cttccttgcg atgaatacga ttttaacagc
    24061 gattaaattg tcaactggtc tgtatggata caaactagga acaactgtga ttgataaact
    24121 aagcgaacag atggcaacga tttctcgtat tgccaatatt atcggtgtaa ccgtaattgc
    24181 tggtttggca gcgacatctg ttaagattat ggtgccgatt acctttgctg caggggaagt
    24241 taaagcagac gctaaacaaa gtatcgtaag tattcaggga atgcttgata aggttgctcc
    24301 agctcttcta ccagccctat ttacactttt agtttactac ttgatcaaag aaaagaaatg
    24361 gacaacatat aaactcgtta ttttaacagt tgtcatcgga attatcggaa gctggcttaa
    24421 gattatagct taatggatac aacattgttt tatggaatag tgattgtctt ggcagtgagt
    24481 ccccttttac tgtcaagctt tcattctatt cgtcagcaaa agttgcttcg caaacagacg
    24541 gagcaacgac aagagtattt agcttcttta acatctggtg atgaagtgtt gttattgtct
    24601 ggaattcatg gaaaaatcat ttctatcaaa gatgacttgg tctccttgca gattgcaaaa
    24661 ggtgtggtca tctatgtaga aaaggaaagt gtaatgggaa agacaaaaga actgcttttt
    24721 aagtagttct ttttctggta atagataatg aaagaagaaa gaagacaatt ttttgaaaga
    24781 gtcgatggaa accaatgtcg tgattatatc ttgtcgcact gttcaaaaga ctatgagaaa
    24841 gtcaagagtt cccttgaacg cttgatggac aatcgtttta tgtttgatag tccttgggat
    24901 atggagcctt gttcaaaaat ccatcaaatc cagccgatgg tatgggatca agtatttgaa
    24961 gatgatccag aatgggctta tatgctcaat cgacaagaat atctcttgca gtttatgata
    25021 gggtatgtgg tagaaggaga taaggactat attcaaaagt gcaagttctt tctatttgat
    25081 tggattgagc aggtgagaga attttctcct caatccttga tgactagaac cttggatacg
    25141 ggtattcgtt cctttacttg gttgaaacta ctcttgctcc tcttgaaatt tgacatgcta
    25201 gaggagaaag aactagagaa aattttggtc agtctagaaa agcagattga ctttatgaaa
    25261 agctactatc gcgccaagta cacccttagt aactggggga ttttacaaac aattccgatg
    25321 cttgctatct attatttctt ttcagataag atggacctag aagaagctta ccattttgct
    25381 tcagaggagt tgaaacagca aattgagaca cagattttag gagatggaag ccagtttgaa
    25441 cagtcgattc tctatcatgt agaggtttat aaagccttgc tggatttgtg tctcttgctt
    25501 ccagacttgc aagatagtta ccgagagttg ctggaaaaga tggcgaccta tattcaaatg
    25561 atgacaggct tagatggacg aactttggct tttggtgata gcgattctac agaaacgaca
    25621 gaaattttga gcctgtctgc tgtggttttg aacaaggaag accttcttaa cggtctggat
    25681 gttaaagtcg atttgcttag cctcttgttc ctggggcgag aaaaggtcaa gcgactgcag
    25741 gaatttgaaa agagagcttg gcagcctaag tccatgatct ttgaagactc tggacatgtc
    25801 tgcattaagg atgaacatcg ttatctattt ttcaaaaatg gtccgctagg aagtgcccat
    25861 agccatagtg acgagaatag tttttgctta cagtatcaag gacaacctat tttcatagat
    25921 gctgggcgtt attcttatcg ggagatatat gaacgttatc tcttaaagag tgcttggagt
    25981 cattcgacct gcattgtaga tgggaaagct ccggaaagaa tcacgggatc ctgggaatat
    26041 gaatactatc ctcactccct gttttgtcac cataaagaaa gggagggagt gcattatatt
    26101 gaaggggctt attggtcagc agaacctgat ttgccttatc ttcacaagag aaaaatcctc
    26161 atgttggtag aggatgtctg gctcttggtg gatgacatca ggtgtcaagg tcagcatgag
    26221 gcgttgactc agtttatcct tgacaaggat gtgacctatc aagatgggaa aatcaatcag
    26281 ttgagactat ggagtgaagt tgattttgat ttggaagata ccatcatttc tcctaaatac
    26341 aatgagcttg aaagaagtaa caaactcacc aagcgccaat tctttgagaa tcagatgctg
    26401 gattatacca tcattgcgca tgagagtttt gaaatcatcc gtcattctgt ctaccagaca
    26461 gatgatcgtg aagtggaaaa tgctctggct tttgaagtga aaaatgacga aacagacaag
    26521 ctgattctgt tattaagcga ggatatttgt gtaggtgaaa aattgtgcct cgttgacgga
    26581 acaaaaatgc gtggaaaatg tctagtatat gataaaataa atgagagaat gattcgcttg
    26641 cagtgctaga aataggcatt ttgaatagtg aatatgttat aataagtatt agtaggaggt
    26701 gttttagatt ggagaagaaa ctgaccataa aagacattgc ggaaatggct cagacctcga
    26761 aaacaaccgt gtcattttac ctaaacggga aatatgaaaa aatgtcccaa gagacacgtg
    26821 aaaagattga aaaagttatt catgaaacaa attacaaacc gagcattgtt gcgcgtagct
    26881 taaactccaa acgaacaaaa ttaatcggtg ttttgatcgg tgatattacc aacagtttct
    26941 caaaccaaat tgttaaggga attgaggata tcgccagcca gaatggctac caggtaatga
    27001 taggaaatag taattacagc caagagagtg aggaccggta tattgaaagc atgcttctct
    27061 tgggagtaga cggctttatt attcagccga cctctaattt ccgaaaatat tctcgtatca
    27121 tcgatgagaa aaagaagaaa atggtctttt ttgatagtca gctctatgaa caccggacta
    27181 gctgggttaa aaccaataac tatgatgccg tttatgacat gacccagtcc tgtatcgaaa
    27241 aaggttatga gcattttctc ttgattacag cggatacgag tcgtttgagt actcggattg
    27301 agcgggcaag tggttttgtg gatgctttaa cagatgctaa tatgcgtcac gccagtctaa
    27361 ccattgaaga taagcatacg aatttggaac aaattaagga atttttacaa aaagaaatcg
    27421 atcccgatga aaaaactctg gtatttatcc ctaactgttg ggccctacct ctagtcttta
    27481 ccgttatcaa agagttgaat tataacttgc cacaagttgg gttgattggt tttgacaata
    27541 cggagtggac ttgcttttct tctccaagtg tttcgacgct ggttcagccc tcctttgagg
    27601 aaggacaaca ggctacaaag attttgattg atcagattga aggccgtaat caagaagaaa
    27661 ggcaacaagt cttggattgt agtgtgaatt ggaaagagtc gactttctaa aatgaaggaa
    27721 aatgacttgc aatctctgtt aagaaataaa ataatcccac ctagaacaag ctaggtggga
    27781 ttatttgctt atgaaatgag aaattatggg agcaagctcc taaatcaact gtttttgatc
    27841 tacttcttta actacttgat aaaagttata gaagtaggcc aaacttgaaa tgatggttac
    27901 gactaggaat attgaaaatt tccattggac agggttggtt aaaagttgtg gaaaggatat
    27961 gaggagaaag aagagggctg cgttgaggac aggtatccgt tttgattgta ttttctcaag
    28021 tcctttattg agcgcaggaa gaaagaggag taggagtagt aaaactgtat gagaaacagc
    28081 tcctgaaata agggcgaaga aaaggaaaat actgataaaa acatgaatgt tcagtagtct
    28141 agctagtgat ttcataaggc acctcctaat cctggtcttt tttagctctt gcaatacgaa
    28201 gtgagtcgac aatatgtatc atcactccga aaaagaaagc tcccagtata gttttaaaaa
    28261 tatgttttgt atttagaaga gaactgataa aatttggatt ttcacttgtt agggtatcaa
    28321 tgagtggaat tataaaaaat atcactgttc cataaatcga acctgctttc agaccaggat
    28381 aacgtaactg tttcttttct tttttcatga gtttcctcct aatcctcatc ttgatttttc
    28441 ttagtttttg caatgcgacg ggagatgagg aactgtatgc tcgctccgaa gaaaatagaa
    28501 ccgagaatac ttgatacacc atttcttata gtgagaagag aatgaaaata gtcctgacct
    28561 tcatctatga gtatactgag aagaggagtt ataaaaaaca tccatagacc aaagaacaaa
    28621 cctgctttca gacctgggta gtgtagttgc ttgctttctt tctcattcag catatctggt
    28681 tcaatgactg tgatgcctgt ttttttcatt tggtaggtga catagccagc agcgatgagg
    28741 gcaatcacta aaatcagagg aggatagatt agagccactt cttgagggta tttataggct
    28801 agaaggagtg gaataagatt tccgaaaatc atcagataaa agaggacgat aaagacttgg
    28861 ttcccaatac tatcggcctc acgccgtttg tattcgtcaa ggggaccaga aataccgtat
    28921 gtgcgtttga tcagtttttc agtgaaggtt tcttttttca tgagtttgct ccttttttaa
    28981 aaatcttcct cccaaaagag actgttgagg tcagtttgga ggctgcgggc gagattgaga
    29041 cagagttcca aggttggatt gtacttgtcg ttttcaatca tattgatagt ctgtctcgag
    29101 acaccgatat ccttggcgag ttcgagctgg gaaataccca attccttgcg aaattctttc
    29161 acacgattca tctggtctcc tttctgattt atgtcgtata tatttgacta tattatagtc
    29221 ttttaaacat aaagtgtcaa gtatatttga catatttttt gaagaaatag tagtctcctt
    29281 gtcctatttg tctgacaagt gcaagctggt cggatttgtg gtaaaataga taagatatga
    29341 caaaagaatt tcatcatgta acggtcttac tccacgaaac gattgatatg cttgacgtaa
    29401 aacctgacgg tatctacgtt gatgcgactt tgggtggagc aggccatagc gagtatttat
    29461 taagtaaatt aagtgaaaaa ggccatctct atgcctttga ccaggatcag aatgccattg
    29521 acaatgcgca aaaacgcttg gcaccttaca ttgagaaggg aatggtgacc tttatcaagg
    29581 ataacttccg tcatttacag gcacgtttgc gcgaagctgg tgttcaggaa attgatggaa
    29641 tttgttatga cttgggagtg tctagtcctc aattggacca gcgtgagcgt ggtttttctt
    29701 ataaaaagga tgcgccactg gacatgcgga tgaatcagga tgctagtctg acagcctatg
    29761 aagtggttaa tcactatgac tatcatgatt tggttcgtat tttcttcaaa tacggtgagg
    29821 ataaattctc taaacagatt gcgcgtaaga ttgagcaagc gcgtgaagtg aagccgattg
    29881 agacaacgac tgagttagca gagattatca agttggtcaa acctgccaag gaactcaaga
    29941 agaagggtca tcctgctaag cagattttcc aggctattcg aattgaagtc aatgatgaac
    30001 tgggagcggc agatgagtcc atccagcagg ctatggatat gttggctctg gatggtagaa
    30061 tttcagtgat tacctttcat tccttagaag accgcttgac caagcaattg ttcaaggaag
    30121 cttcaacagt tgaagttcca aaaggcttgc ctttcatccc agatgatctc aagcccaaga
    30181 tggaattggt gtcccgtaag ccaatcttgc caagtgcgga agagttagaa gccaataacc
    30241 gctcgcactc agccaagttg cgcgtggcca gaaaaattca caagtaagag ggaaaaagat
    30301 ggcagaaaaa atggaaaaaa caggtcaaat actacagatg caacttaaac ggttttcgcg
    30361 tgtggaaaaa gctttttact tttccattgc tgtaaccact cttattgtag ccattagtat
    30421 tatttttatg cagaccaagc tcttgcaagt gcagaatgat ttgacaaaaa tcaatgcgca
    30481 gatagaggaa aagaagaccg aattggacga tgccaagcaa gaggtcaatg aactattacg
    30541 tgcagaacgt ttgaaagaaa ttgccaattc acacgatttg caattaaaca atgaaaatat
    30601 tagaatagcg gagtaagata tgaagtggac aaaaagagta atccgttatg cgaccaaaaa
    30661 tcggaaatcg ccggctgaaa acagacgcag agttggaaaa agtctgagtt tattatctgt
    30721 ctttgttttt gccatttttt tagtcaattt tgcggtcatt attgggacag gcactcgctt
    30781 tggaacagat ttagcgaagg aagctaagaa ggttcatcaa accacccgta cagttcctgc
    30841 caaacgtggg actatttatg accgaaatgg agtcccgatt gctgaggatg caacctccta
    30901 taatgtctat gcggtcattg atgagaacta taagtcagca acgggtaaga ttctttacgt
    30961 agaaaaaaca caatttaaca aggttgcaga ggtctttcat aagtatctgg acatggaaga
    31021 atcctatgta agagagcaac tctcgcaacc taatctcaag caagtttcct ttggagcaaa
    31081 gggaaatggg attacctatg ccaatatgat gtctatcaaa aaagaattgg aagctgcaga
    31141 ggtcaagggg attgatttta caaccagtcc caatcgtagt tacccaaacg gacaatttgc
    31201 ttctagtttt atcggcctag ctcagctcca tgaaaatgaa gatggaagca agagcttgct
    31261 gggaacctct ggaatggaga gttccttgaa cagtattctt gcagggacag acggcattat
    31321 tacctatgaa aaggatcgtc tgggtaatat tgtacccgga acagaacaag tttcccaacg
    31381 aacgatggac ggtaaggatg tttatacaac catttccagc cccctccagt cctttatgga
    31441 aacccagatg gattcttttc aagagaaggt aaaaggaaag tacatgacag cgactttggt
    31501 cagtgctaaa acaggggaaa ttctggcaac aacgcaacga ccgacctttg atgcagatac
    31561 aaaagaaggc attacagagg actttgtttg gcgtgatatc ctttaccaaa gtaactatga
    31621 gccaggttcc actatgaaag tgatgatgtt ggctgctgct attgataata atacctttcc
    31681 aggaggagaa gtctttaata gtagtgagtt aaaaattgca gatgccacga ttcgagattg
    31741 ggacgttaat gaaggattga ctggtggcag aatgatgact ttttctcaag gttttgcaca
    31801 ctcaagtaac gttgggatga ccctccttga gcaaaagatg ggagatgcta cctggcttga
    31861 ttatcttaat cgttttaagt ttggagttcc gacccgtttc ggtttgacgg atgagtatgc
    31921 tggtcagctt cctgcggata atattgtcaa cattgcgcaa agctcatttg gacaagggat
    31981 ttcagtgacc cagacgcaaa tgattcgtgc ctttacagct attgctaatg acggtgtcat
    32041 gctggagcct aaatttatta gtgccgttta tgatccaaat gatcaaactg ctcggaaatc
    32101 tcaaaaagaa attgtgggaa atcctgtttc taaagatgca gctagtctaa ctcggactaa
    32161 catggttttg gtagggacgg atccggttta tggaaccatg tataaccaca gcacaggcaa
    32221 gccaactgta actgttcctg ggcaaaatgt agccctcaag tctggtacgg ctcagattgc
    32281 tgacgagaaa aatggtggtt atctagtcgg gttaaccgac tatattttct cggctgtatc
    32341 gatgagtccg gctgaaaatc ctgattttat cttgtatgtg acggtccaac aacctgaaca
    32401 ttattcaggt attcagttgg gagaatttgc caatcctatc ttggagcggg cttcagctat
    32461 gaaagactct ctcaatcttc aaacaacagc taaagctttg gagcaagtaa gtcaacaaag
    32521 tccttatcct atgcctagtg tcaaggatat ttcacctggt gatttagcag aagaattgcg
    32581 tcgcaatctt gtacaaccca tcgttgtggg aacaggaacg aagattaaaa acagttctgc
    32641 tgaagaaggg aagaatcttg ccccgaatca gcaagtcctt atcttatctg ataaagtaga
    32701 ggaagttcca gatatgtatg gttggacaaa ggagactgct gagacccttg ctaagtggct
    32761 caatatagaa cttgaatttc aaggttcggg ctctactgtg cagaagcaag atgttcgtgc
    32821 taacacagct atcaaggaca ttaaaaaaat tacattaact ttaggagact aatatgttta
    32881 tttccatcag tgctggaatt gtgacatttt tactaacttt agtaggaatt ccggccttta
    32941 tccaatttta tagaaaggcg caaattacag gccagcagat gcatgaggat gtcaaacagc
    33001 atcaggcaaa agctgggact cctacaatgg gaggtttggt tttcttgatt acttctgttt
    33061 tggttgcttt ctttttcgcc ctatttagta gccaattcag caataatatg ggaatgattt
    33121 tgttcatctt ggtcttgtat ggcttggtcg gatttttaga tgactttctc aaggtctttc
    33181 gtaaaatcaa tgaggggctt aatcctaagc aaaaattagc tcttcagctt ctaggtggag
    33241 ttatcttcta tcttttctat gagcgcggtg gcgatatgct ttctgtcttt ggttatcaag
    33301 tgcatctagg gattttctat attgtcttcg ctcttttctg gctagtcggt ttttcaaacg
    33361 cagtaaactt gacagacggt gttgacggtt tagctagtat ttccgttgtg attagtttgt
    33421 ctgcctatgg agttattgcc tatgtgcaag gtcagatgga tattcttcta gtgattcttg
    33481 ccatgattgg tggtttgctc agttttttca tctttaacca taagcctgct aaggtcttta
    33541 tgggtgatgt gggaagtttg gccctaggtg ggatgctggc agctatctct atggctctcc
    33601 accaagaatg gactctcttg attatcggaa ttgtatatgt ttttgaaaca acttctgtta
    33661 tgatgcaagt cagttatttc aaactgacag gtggtaaacg tattttccgt atgacgcctg
    33721 tacatcacca ttttgagctt gggggattgt ctggtaaagg aaatccttgg agcgagtgga
    33781 aggttgactt cttcttttgg ggagttgggc ttctagcaag tctcctgacc cttgcaattt
    33841 tgtatttgat gtaagaatgg caccctgatg tttcagggtg tttttgtgtt taaatacaca
    33901 atgaaaatca aagaacaaac tagaaagcta actttaggct gctcaaaata tagtagattg
    33961 aaactagaat agtacacctc tacttctaaa acatttttag aaatcgattt gactgtcctg
    34021 aacgatttat cctgttctta tttcatttta ctatacagtt ttgagatggt tgatagaact
    34081 gacgaagtca gctcaaaaca ctgttttgag gttgtagaca aggcgaagct gatgtggttt
    34141 gaagaggttt tcgaagagtg taaaaaaata ttggtcagtt aaagtcaaaa ctcttgacct
    34201 tttctgacca atgtagtata ttatgaacgt aaggtaaatg aaagccttac tagaacactt
    34261 atttaaagta aaatagaaag aggtgagtct atgtttcatc tagcaatctt cagaggtaaa
    34321 gatagtctac tcctgcttga aaaagaaaaa ccagaaatag tacgtagggt agcgatctag
    34381 ctagtctaaa ttttttaaaa caatggtcaa agatagtcaa tatcagtaat cataactaag
    34441 taaacaaaaa gaggtaaaga atatgaataa caactttaat aattttaata acatggatga
    34501 tttatttaac caattgatgg gtggtatgcg aggatatagt tctgaaaatc gccgttactt
    34561 aattaatgga cgcgaagtca cacctgagga atttgctcac tatcgtgcga ctggtcaatt
    34621 accaggaaat gcagaaactg atgtgcaaat gccacaacag gcatcaggta tgaaacaaga
    34681 cggtgtcctt gcaaaactag gtcgaaactt aacagcagaa gcgcgtgagg gcaagttgga
    34741 tcctgttatc ggacgaaaca aggaaattca agaaacatct gaaatcctct cacgccgcac
    34801 caagaacaat cctgttttgg tcggagatgc aggtgttggt aagacagcag ttgtcgaagg
    34861 tctagcgcaa gccattgtga acggagatgt tcctgctgct atcaagaaca aggaaattat
    34921 ttccattgat atctcaggtc ttgaggctgg tactcaatac cgtggtagct ttgaagaaaa
    34981 tgtccaaaac ttagtcaatg aagtgaaaga agcagggaat attatcctct tctttgatga
    35041 aattcaccaa attcttggtg ctggtagcac tggtggagac agtggttcta aaggacttgc
    35101 ggatattctc aagccagctc tctctcgtgg agaattgaca gtgattgggg caacaactca
    35161 agacgaatac cgtaacacca tcttgaagaa tgctgctctt gctcgtcgtt tcaacgaagt
    35221 gaaggtcaat gctccttcag cagagaatac ttttaaaatt cttcaaggca ttcgtgacct
    35281 ctatcaacaa caccacaatg tcatcttgcc agacgaagtc ttgaaagcag cggtggatta
    35341 ttctgttcaa tacattcctc aacgtagctt gccagataag gctattgacc ttgtcgatgt
    35401 aacggctgct cacttggcgg ctcaacatcc agtaacagat gtgcatgctg ttgaacgaga
    35461 aatcgaaacg gaaaaagaca agcaagaaaa agcagttgaa gcagaagatt ttgaagcagc
    35521 tctaaactat aaaacacgca ttgcagaatt ggaaaggaaa atcgaaaacc acacagaaga
    35581 tatgaaagtg actgcaagtg tcaacgatgt ggctgaatct gtggaacgaa tgacaggtat
    35641 cccagtatcg caaatgggag cttcagatat cgaacgtttg aaagatatgg ctcatcgctt
    35701 gcaagaaaag gtgattggtc aagataaggc cgtagaagtt gtagctcgtg ctatccgtcg
    35761 taaccgtgct ggttttgatg aaggaaatcg cccaatcggc agcttcctct ttgtagggtc
    35821 tactggggtt ggtaagacgg agcttgctaa gcaattggca ctcgatatgt ttggaaccca
    35881 ggatgcgatt atccgtttgg atatgtctga atacagtgac cgcacagctg tttctaagct
    35941 aattggtaca acagcaggct atgtgggtta tgatgacaat agcaatacct taacagaacg
    36001 tgttcgtcgc aatccatact ctatcattct cttggatgaa attgaaaagg ctgatcctca
    36061 agttattacc cttctcctcc aagttctaga tgatggtcgt ttgacagatg gtcaaggaaa
    36121 tacagtaaac ttcaagaata ctgtcgttat tgcgacctca aatgctggat ttggctatga
    36181 agccaacttg acagaagatg cggataaacc agaattgatg gaccgtttga aacccttctt
    36241 ccgtccagaa ttcctcaacc gctttaatgc agtcatcgag ttctcacact tgactaagga
    36301 agacctttct aagattgtag atttgatgtt ggctgaagtt aaccaaacct tggctaagaa
    36361 agacattgac ttggtagtta gtcaagcggc taaagattat atcacagaag aaggttacga
    36421 cgaagtcatg ggggttcgtc ctctccgtcg cgtggttgaa caagaaattc gtgataaggt
    36481 gacagacttc cacttggatc atttagatgc taaacatctg gaagcagata tggaagatgg
    36541 cgttttggtt attcgtgaga aagcctaaga tagaattttg aggataaaaa agaaggagcc
    36601 agctgaaaaa aactggttcc tttttaggta cgacaggcat gtcgtatagt agaagtgtat
    36661 tattccagtt tcaatatact atagtagctc agaagtcggt acttaaacgt gctatatcaa
    36721 aaccagtcct tgaaaaacgt ggactggttt cgtgtttgga ttattacctt gaacgacatg
    36781 cgttaaaagt tagttgaacc gccgtatgcc gaacggtacg tacggtggtg tgagaggggc
    36841 tagagattat cccctactcg attgtctata gctatagggg taaagttatt agagaggttg
    36901 ctagtttata gagacatctt gatttgtaaa aagttaaatt ttagacaatt atccccttta
    36961 aaaaatctat taaaccatag ctagttgaag taaattttta tagaacataa ttttatttat
    37021 caagacattg tagagttgag gcaaattgaa aaagaaagtt taaaagttga taataagtca
    37081 ataagaaagc tattaattct aacgagatta tttgatagta atttgttttt tcagctacta
    37141 ttcggacaat gttattataa taaacacagg agagaacacc agaaggtagg gacatcagaa
    37201 gaaatagttc aggatatagt taacataatc atcaaagaag ctcctagact cgctaatgtt
    37261 aatttggaaa catattatcc agatgaatat atgtcaaata cattgaagca attactactt
    37321 tttagagagg agttcataaa aaatattttg aatgggattg atgtggatga aacagtagta
    37381 atagaaaatg attttgtaga agagttggag aactttttaa aagagaatga tttgctagat
    37441 ttttcaaata gcatattttt tcagttatct ggagataaag taatagtgaa taatatttat
    37501 ccaggatatt tagcatattt taataggttc cttacatttt atccgaaaat attcgctatt
    37561 aaagaagttg gagaatatat tgacttttta aattttgaaa agagaattgc ggatatgttt
    37621 tattgttggg gatttaatgc aaattctaga gtgttgacag ctgaaaaaat aattgaaatc
    37681 ccaaatcacc aaatcaatgc taagtacata aaaaaagtta taaaaatgag tgaactcttg
    37741 tttggtgttg atagtaataa cagaattcgg ttgcttaaca atagaaggga attgataaaa
    37801 actattttcc aaggttctgt aattaagtca gcaattcctg ctctagctgc tactttggat
    37861 acaatcagta acagtggatc atttcaaatt tctttatcaa agcagataat taataattta
    37921 gtattaagtg gtaaagataa agttacaatt cctaggatag agttagataa tgttgttctt
    37981 tcaagacaga agattattgt atcagtttcg tatataaatg attttttgga tttgagattt
    38041 ccagataaaa tagaatacat tttaaatttt ttagaaggat ctggtttcaa tactaaagta
    38101 atggtctact ttgggaaaat tgtagaagaa gataagaact attttgttaa tcttgaaaaa
    38161 cctcagtatt ttgattttac cagtatactt ttcaataagt tattctttaa agaattaaac
    38221 aagtttgatt acatggttat tgaagaactc attccaaatc ttgatgaaga tgtaatgatg
    38281 acagagtata taaaagagta tactgaatag gagcaatcta ttatgatttt aagtaaagta
    38341 cgttgttaca tatataattc taaaattaga ggtaaagttc tgtatgaatt atatgaattt
    38401 ataaatgaaa ataagcaatt gatggacgca attaattcaa ttaaagttga cagtagtaat
    38461 ggttttagta ttcaaatatt acatttagga gaacagcaaa caactgtctt attaacagat
    38521 ttttttacta aaactttaga cttgtttaag gaatttaggg ttacaaataa gagtactctt
    38581 gagcaggtga aaaatcaaat tagcatacta aattcttctg gtccaaaaat ggatttaac
//
LOCUS       DAVBEM010000015        37452 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVBEM010000015 DAVBEM010000000
VERSION     DAVBEM010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37452
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.015"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(<1..777)
                     /locus_tag="VQ548_000793"
     CDS             complement(<1..777)
                     /locus_tag="VQ548_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2653674.1"
                     /translation="MSKETVVYTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYAFTDYYLLTPDERKFVGLENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMVY"
     gene            complement(873..2183)
                     /locus_tag="VQ548_000794"
     CDS             complement(873..2183)
                     /locus_tag="VQ548_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET2653675.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITL
                     DGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYN
                     KKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYM
                     PLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYP
                     MLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASE
                     FVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVA
                     YPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            complement(2310..3305)
                     /locus_tag="VQ548_000795"
     CDS             complement(2310..3305)
                     /locus_tag="VQ548_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2653676.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFGGDKTTKKI"
     gene            complement(3667..5148)
                     /locus_tag="VQ548_000796"
     CDS             complement(3667..5148)
                     /locus_tag="VQ548_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2653677.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSS
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            5591..5755
                     /locus_tag="VQ548_000797"
     CDS             5591..5755
                     /locus_tag="VQ548_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET2653678.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            5839..6405
                     /gene="amaP"
                     /locus_tag="VQ548_000798"
     CDS             5839..6405
                     /gene="amaP"
                     /locus_tag="VQ548_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HET2653679.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            6417..6587
                     /locus_tag="VQ548_000799"
     CDS             6417..6587
                     /locus_tag="VQ548_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HET2653680.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            6626..7234
                     /locus_tag="VQ548_000800"
     CDS             6626..7234
                     /locus_tag="VQ548_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2653681.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            7265..7468
                     /locus_tag="VQ548_000801"
     CDS             7265..7468
                     /locus_tag="VQ548_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET2653682.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(7578..7856)
                     /locus_tag="VQ548_000802"
                     /pseudo
     CDS             complement(7578..7856)
                     /locus_tag="VQ548_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895264.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            8054..8341
                     /locus_tag="VQ548_000803"
     CDS             8054..8341
                     /locus_tag="VQ548_000803"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET2653683.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCSRQRRLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(8619..9389)
                     /locus_tag="VQ548_000804"
     CDS             complement(8619..9389)
                     /locus_tag="VQ548_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HET2653684.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(9404..10252)
                     /locus_tag="VQ548_000805"
     CDS             complement(9404..10252)
                     /locus_tag="VQ548_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HET2653685.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDRFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(10249..11724)
                     /locus_tag="VQ548_000806"
     CDS             complement(10249..11724)
                     /locus_tag="VQ548_000806"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HET2653686.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYVSDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTSLKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(12047..13402)
                     /locus_tag="VQ548_000807"
     CDS             complement(12047..13402)
                     /locus_tag="VQ548_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2653687.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(13412..13729)
                     /locus_tag="VQ548_000808"
     CDS             complement(13412..13729)
                     /locus_tag="VQ548_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2653688.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(13746..14063)
                     /locus_tag="VQ548_000809"
     CDS             complement(13746..14063)
                     /locus_tag="VQ548_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2653689.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(14076..15761)
                     /locus_tag="VQ548_000810"
     CDS             complement(14076..15761)
                     /locus_tag="VQ548_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HET2653690.1"
                     /translation="MKNKKLISSLFILFLLIFIHVKVFANENLIKNSNFEQGELFWNS
                     RNRGIINSNESYSNGHYSGMIPSTAINDNRADGYIGQVIDIEPNEDYLVSAFAKVDIS
                     GAEGYFTARWFDNNKQGEIVQNNIGEAVDQTVNTTEWKKYMFSFNSGKHDKVLIQLVK
                     WSEDDTTKKSNIFIDNVEMYQLSKGNSYKKIWRDDFDGEQLNKKYWGYELGSIRGWEQ
                     QHYVRSDENVFLRSGNLVLRATNRSKEDQYFNPRNNHRKVVYNSGSVRTHGKVEFLYG
                     KLEMRAKLPKGQGVFPAFWTLGSDFTLDGKINPVQGRGWPSTGEIDIMELVGERNSNG
                     SGNKTVYQTLHYGQSDNDDGKFAGRGTAFKLSSGNFNDSYHTFSIDWYKDYIVWMVDN
                     HIVRKVYYGSDNIAKKIFNRPQYVQLNLAMGGSWPGVVDNNLSGTEFVVDYVSYSRND
                     LQQHQAEEYYSQSPKINGAKDIVINRGDVPDLLKGITTNSGYELDYSIENEPMFNNFG
                     GNTSVDLLIRNKTEKEKISQMPPGVYNLHYTSRPKHLDYESKVDRKTVTLTIK"
     gene            complement(15766..16662)
                     /locus_tag="VQ548_000811"
     CDS             complement(15766..16662)
                     /locus_tag="VQ548_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HET2653691.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(16665..17927)
                     /locus_tag="VQ548_000812"
     CDS             complement(16665..17927)
                     /locus_tag="VQ548_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2653692.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFITGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQGALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPSWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            18207..19385
                     /locus_tag="VQ548_000813"
     CDS             18207..19385
                     /locus_tag="VQ548_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET2653693.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(19613..20059)
                     /locus_tag="VQ548_000814"
     CDS             complement(19613..20059)
                     /locus_tag="VQ548_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2653694.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLPLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSGLKLE"
     gene            20129..20788
                     /locus_tag="VQ548_000815"
     CDS             20129..20788
                     /locus_tag="VQ548_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HET2653695.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCVIIFGKLLL
                     V"
     gene            complement(20840..21991)
                     /locus_tag="VQ548_000816"
     CDS             complement(20840..21991)
                     /locus_tag="VQ548_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET2653696.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(22006..22737)
                     /locus_tag="VQ548_000817"
     CDS             complement(22006..22737)
                     /locus_tag="VQ548_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653697.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            22966..23067
                     /locus_tag="VQ548_000818"
                     /pseudo
     CDS             22966..23067
                     /locus_tag="VQ548_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(23039..23815)
                     /locus_tag="VQ548_000819"
     CDS             complement(23039..23815)
                     /locus_tag="VQ548_000819"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HET2653698.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(23808..25031)
                     /gene="trpB"
                     /locus_tag="VQ548_000820"
     CDS             complement(23808..25031)
                     /gene="trpB"
                     /locus_tag="VQ548_000820"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HET2653699.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGFGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(25009..25608)
                     /locus_tag="VQ548_000821"
     CDS             complement(25009..25608)
                     /locus_tag="VQ548_000821"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HET2653700.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVAADLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(25595..26362)
                     /gene="trpC"
                     /locus_tag="VQ548_000822"
     CDS             complement(25595..26362)
                     /gene="trpC"
                     /locus_tag="VQ548_000822"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HET2653701.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDC
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNTGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(26359..27363)
                     /gene="trpD"
                     /locus_tag="VQ548_000823"
     CDS             complement(26359..27363)
                     /gene="trpD"
                     /locus_tag="VQ548_000823"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HET2653702.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEDYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(27374..27940)
                     /locus_tag="VQ548_000824"
     CDS             complement(27374..27940)
                     /locus_tag="VQ548_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HET2653703.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMICDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(27937..29298)
                     /gene="trpE"
                     /locus_tag="VQ548_000825"
     CDS             complement(27937..29298)
                     /gene="trpE"
                     /locus_tag="VQ548_000825"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HET2653704.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQAIDRDPLDFLYEVTHKSQHHSDLPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRSVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(29799..29876)
                     /locus_tag="VQ548_000826"
                     /pseudo
     CDS             complement(29799..29876)
                     /locus_tag="VQ548_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(30481..31482)
                     /locus_tag="VQ548_000827"
     CDS             complement(30481..31482)
                     /locus_tag="VQ548_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2653705.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            complement(31590..31958)
                     /locus_tag="VQ548_000828"
     CDS             complement(31590..31958)
                     /locus_tag="VQ548_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653706.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            complement(32054..32764)
                     /locus_tag="VQ548_000829"
     CDS             complement(32054..32764)
                     /locus_tag="VQ548_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HET2653707.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            complement(32767..34458)
                     /locus_tag="VQ548_000830"
     CDS             complement(32767..34458)
                     /locus_tag="VQ548_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2653708.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDPNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            complement(34470..35480)
                     /locus_tag="VQ548_000831"
     CDS             complement(34470..35480)
                     /locus_tag="VQ548_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2653709.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            complement(35583..36650)
                     /locus_tag="VQ548_000832"
     CDS             complement(35583..36650)
                     /locus_tag="VQ548_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2653710.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            complement(36675..37334)
                     /locus_tag="VQ548_000833"
     CDS             complement(36675..37334)
                     /locus_tag="VQ548_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HET2653711.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
BASE COUNT        12046 a         7633 c         5730 g        12043 t
ORIGIN      
        1 gtacaccata gtaattgttg agtttaatgg gccaccttgc gtcataacca ttggttgtac
       61 aatcagctta aaagcagaaa ttaaagttgt taacaataca aacagggctg ttggttttag
      121 taggggcatc gtgatataac gaaactgagc ccattttgag aatccatcta attcagcagc
      181 ttcatagaca tcttgtggaa tattctgcat tcctcctaaa aataaaagca tctgataacc
      241 tgcaccctgc caagcagaaa caaaaacaat tgcatacata gcttgtttag gactagtcaa
      301 gaaaggttga gaagcaatac ctaccttatt taaaatagca tttaataagc cactatttgg
      361 atttaaaaga taaagccaaa gaatagaaat aactaccaag gacatgacaa ctggagcaaa
      421 aaaagccact ttaaaaaaca tatttccttt tcgcttttta ttgacaatca aagccattcc
      481 taaggccgct cccaattgaa ctggaataat ccaaacaaca aatttcaaag tattcaagaa
      541 gctctttaag aaaatcggat cttttgttaa tcgaataaaa ttttcaagtc caacaaattt
      601 tctttcatct ggtgtcaaca aataataatc tgtaaaagcg taataaatga ccattccaac
      661 tggaattact aaaaagatac ctaataaaat taaagctgga gctaaaaaac tataacctaa
      721 tatgttatcc tttatttttt cacgtctttt tgtatacaca acagtttctt tactcatatc
      781 catctccttt aatcatatat atcaaactag gctattaaca agaaagggga aggtagttcc
      841 aaacattttc cttccacctt cttttttaca gattatttga gtgactgatc aatagcagtt
      901 tgcatttctt ttgtacgagt atccaagact ttttgcacat ttggattttc ttcataatag
      961 ctaatatctt gcattgcttg ttgaaaagct cgagaaacct gaggatatgc tacgacaact
     1021 gggcgagcat gagctgtttt tgaattttgt tccatcaaga aacgcattgg ttcggatact
     1081 ttatctttga tattttcaat tgtagattta cgaattggaa ggaccgaatt ccccaagcta
     1141 ataatttcac ttgattctgt atttgtagca aatttaacaa attcagatgc ggcctctttt
     1201 ttatcagatt ttgtcgtcac agctaattgc caactacctg aaggggatac taattttttc
     1261 gtcttactag atactgggta aggaaggata ccaaaatcaa tatctttgta gtttgtattc
     1321 atgtcagcaa tcgtccaaga accactcaaa agcattggat actctcctgt ttcaaaacct
     1381 ttttcgactg gactaacagt tgtatagcct tcttttacaa gattttgaat gaattgaact
     1441 gcttctacac tctctttgga gttgaagtat ccttctgcct ttgttccatc ttcgtttacg
     1501 acagaaccat tatttgacca aatcaacggc atataagcat atggcaacat ttcatcgttt
     1561 gaattaatac gaaaatcaat tgctggtttg ttataatgat ctttcaattt tttagcaatc
     1621 gtattaaatt cgtcccatgt ccatggcttt tctagcgttg gaagctctga ttccgcaatt
     1681 ccagcctctt tgaacatttt tttattgtaa taaacaccaa cattcgattc agaaaatcca
     1741 aatgcataga atttcccatt ataagttccc tgttgtttaa tactgtccaa aacatcatcc
     1801 atattattat cttttagata atcatctagc ggagtaatta ctttagattt tgcataagct
     1861 gccgtatttg gtccatcaag ggtaataaca tctggaagac tattagtcgt aatagcagca
     1921 ttaaccttgt cttcatatcc tccaccacta ccactacgag gaatatactc agttacaacc
     1981 ttgtacttac tttttcctga ttgattaaag ttatcaacaa ctttttgcca agcttttcct
     2041 tcatttgttt cgtcagagaa ttgtacccag actttaatat catttgaaga actcgcttgt
     2101 tttgagttag ttcctccact acaacctgca agtatagcta acgatagccc cgcaacaaca
     2161 gataacattg tacctttacg catcattttt ctcctttttg aaacgtttca ttttttattt
     2221 attttttaaa caagcttcta gcctattttt gaaacgtttc atttgttgat tatattataa
     2281 cagcgctttc attaattgtc aagcgctttt taaatttttt ttgttgtttt atctccccca
     2341 aaatatgtgg gaattacgat tcgtttttct agaatctctt ctcgcttaat cattttcagt
     2401 atcattgcaa cagattcttt tgccatcata ccaatatctt gaactattgt agacactaga
     2461 taagattgat cgacagaagt ttttaaacca tcaaacccaa ttatctggta atcatcaggt
     2521 gctattttcc ccagttcttt cataacacta ataactctca gagccatcat atcatttatt
     2581 gtaaatatac catcaatttc tttatgagat tgcaaaaaaa ttcttatctg atcttcagga
     2641 tttattaaag gttctttcat ttcaaaatta tagacatcta ctcctaattc cttagctttt
     2701 tctctgaatc ctttacttct gagtatagtc tcattctcat acatattaat tgaaccaata
     2761 aaagcaaggt gcttattatc ccttctaacc agttcctctg ctgcagtttg tcctcctttg
     2821 taatttgctg aagtaacata gcatacattt tccgaaaaat gtctatctat acttacaaac
     2881 ggtaaatcag ataaaatata tttgtcaata tcagaatatg taataccaat aattccatcc
     2941 actttatttt gtttcaacat ttcgatatat tcgatttcat tttgtgaatc gctatcagcg
     3001 ttacaaataa ataatttata attatatttt aataactctt tctcaacatg ataggcaaac
     3061 tccgaaaaaa atggatgcca tatgctcgga ataatcaaag cgatagtttc tgttctattc
     3121 tttttcatac ctcgagcata attatcaggg atatagtcca atgtttttat agccctttga
     3181 actttcctta aagttacttc tttaatgcct ttttctttat taattacacg tgaaacagtt
     3241 ccaacactaa ctcctgcttc taaagcaaca tctttcatgg taattgattt tctttgttct
     3301 accatattat cacctccttt caatatatag tatcatgcaa atgcttttta agcaactatt
     3361 tctcaatcat ttttggccag atcatttatc ccatcatgaa taaaatcact ccaattagct
     3421 tttgaaaata cttcaatttt catgtgtaaa catctacata aaacaggaaa agccttggtt
     3481 ttatggcttt tttcgtatct tctacaaaaa aagcaagagt tttagagggc tataaatcta
     3541 gatgtacatt ttgcttaaat gattgaaggt cttttcttaa caaaaacacc ccaaaaatta
     3601 gattttttct gtctaacttt tgaggtacag ttcaaacgcg aaatagcgtt tttttgttat
     3661 ttttggttac tcatctaatc gaataaacat catggcattt aacaaatata tgagtgagac
     3721 cgtgtttata ttatttgaat agatgagtct cttattttca ataggaggaa taataaaatt
     3781 agaaataatg atatcataag atgaatcttc taaagattcc tttgataatt ctaattcagt
     3841 ccaaacttcc agttcaaaat tattgctaca gtaataagaa agtgtctctg caacgaattt
     3901 tgcatgatac tgatcaaaat tactcataac caaaaccttt agtttaggct gattttgtag
     3961 caaattaatc accaaatgtt tggtatgagt gatgaaggta taagatagat gatttaccat
     4021 cattgaacta gaacaaacct caagagtctc taaatagtga gaaagctctt tttttatatc
     4081 tgaaacaaat tttggaaaaa tattttgaaa gttcctgatt gtattccctt tttgatcaaa
     4141 taaaataaac tcagtaaaca actcttgacg atacagatgt gcggtattat gcagatgcca
     4201 aatcagatta tccttattct ccatttcaat ctgatacttg actgaaatct gatcaataaa
     4261 atcactcaat agatggtaag atttttcaac ataactatcc ttttttacgc atttcataaa
     4321 gagactttca tctatgaaaa acattttttg aaagtaagac acaaataatt ggcaaacaac
     4381 ttcttcatct aaagagatat tgtattctga ttcaaaactc tgagcaacac cttctattcc
     4441 ttctgcctgc attaaaaaat ccaaactttg gtcgttaaaa gaatctttat ctacttccat
     4501 aaaatgacca aactttattc tatataggtt cgtaactagg agcaacttta gcattctatg
     4561 cgttgacaaa ttcattggaa agcttgtttc cttataaacc aattctaaca attgagatag
     4621 tggctctgat gaaaaatttt caaatggcca ttctaggaaa taatattttt ctgaaaaata
     4681 ttgtgcaaaa aagtaacgaa tgtctctctc atttccaatg atttgaacag gggtcagact
     4741 gacttcaaat tgaaattgcc ttttaatcac tttattgatt tggctaataa tacgatagag
     4801 cgaagatgaa ctgatataaa attctttaca aatactctca gcttgacaac cttcattaaa
     4861 gaagatgaat tctaaaatcg aaaaatgagt tgaatgttta aagaaatgat ggtaaaccat
     4921 ttcaatatca ctatcatcgg tattaataat gcgtatacca ttagtagaag aatgaaaaat
     4981 caagtcagga aaagcagatt taacatggga tagatcatct ttgactgcac gttctgtaca
     5041 atttaataac tctgctagtt cagaacgatg aaaccaacgt ttatgttcaa ataataattc
     5101 taataattct aattgcctat gacttttttt agataataaa tctctcatga atatctttct
     5161 ctctttataa attatcggat taaacctctt gcaattatac cacaaagaat aggtatagca
     5221 tgatataacg acttttccta aaatctttta tttcgtataa taacactacg gagacaatat
     5281 ataaacaatt ttcttatttt accgtctatt gagggcgtga atacagaatc aaattcaagt
     5341 ctaaagatta tatttttaat tttaaaaatt atataatagc aacaattaaa gaatttgatt
     5401 ttttaaaatt atataataat aacaatcgaa ataattgact tttctatatt aaagttatat
     5461 aatagtatta atcaaagaaa ttgatttttt gatattaaaa taaaaaagga gggtaggcag
     5521 tgttgtgatc aattattgct ggaggtctta ttggtctctt ggcaggtaaa atcactaaaa
     5581 aagtagttct atgggaatca tcgcaaatgt attcgctggt ttagtcgggg catatgcagg
     5641 acaatctctt ttaggtagtt ggggtccatc aatcgctgga atggctttgc tcccatctat
     5701 tgtaggtgca gcgattgtga ttactgtagt gtcattcttt acaggtagaa agtaaacttt
     5761 tcgccagtaa agttagcaaa ctatttttaa atcaatgacg ggaaaaatag tttaaatgtt
     5821 aaatcgaaag gattgtatat gtcaaaagca aagaaaatat gtttcattat tttctgtatt
     5881 ttaatcttga caattttcct tcctgttttg atagattatc atcaagttag tgatctaggt
     5941 attcatctac ttagctggag acagaactcc gtagttgaat tctatcttgc tagatatgtc
     6001 ttttggggga cagtggttct atcaacttta gttttattat ccattttagt tgtgatgttt
     6061 tatcctaaac gttacttgga aatccaactt gaaactaaaa acgatacatt aaaattaaag
     6121 aattcggcaa tcgaaggttt tgttagaagt ttggtgagtg atcatagatt gatcaagaac
     6181 ccaactgttc atgtaaattt acgaaaaaat aaatgtttcg ttcatgtaga aggtaaaatt
     6241 cttccttcag acaacatcgc tgacagatgc caaataattc aaaatgaaat aactaatgga
     6301 ttgaagcagt tttttggtat tgagcgtcaa gtaaaacttg aagttgcagt aaaaaattac
     6361 caaccaaaac ctcaaaacaa aaagactgtt agtcgtgtga agtaaggaag taaaaaatgg
     6421 aatggcttaa acaatatcga tatccaatta tcgctggtct cataggcgta tttctggctt
     6481 gtttgattgt ctcctttggc ttcttcaaaa caatatttgt attgatttta ggagcactgg
     6541 gagttgcagc tggattatat atcgaaaaaa actatataga taaataaaaa aataaaaatt
     6601 actaatttaa ttaaaggagt ttcatatgtc aaacgaaaaa aacacaaata ctaacgtaga
     6661 aaagaaagat gctactgttg tagctcacga aatcaaaggg gaacttactt acgaagataa
     6721 agttatccaa aaaatcattg gtctttcact agaaaacgtt tcaggtcttt tgggaatcga
     6781 tggtggtttc ttctcaaatc ttaaagaaaa aatcgttaac agcgatgacg taacaagtgg
     6841 tgttaacgta gaagttggta aaacacaagt tgcagttgac ttaaacgtta ttgttgagta
     6901 ccaaaaaaat gttccagctt tatattcaga aatcagagaa atcgtatctt cagaagttgc
     6961 taaaatgact gacttggaaa ttgttgaaat caacgtaaac gttgtcgaca tcaaaactaa
     7021 agaacagcat gaagcagact cagtaagcct tcaagatcgc gtatctgacg ttgctgaatc
     7081 aacaggagaa ttcacttcag aacaattcga aaaagctaaa tctggtcttg gatctggttt
     7141 ctcaactgtt caagaaaaag ttagcgaagg tgtagaagct gttaaaggtg cagcaaatgg
     7201 tgtagtatct cacgaaaaca ctcgtgtaaa ctaagataaa ataaatataa caggagaaat
     7261 tatcatgtca gtagaagaaa aattaaatca agctaaaggt tctattaaag aaggtgttgg
     7321 gaaagccatc ggtgatgaaa aaatggaaaa agaaggagca gctgaaaaag ttgtttctaa
     7381 agtaaaagaa gttgccgaag acgctaaaga cgctgtagaa ggtgctgtag aaggtgttaa
     7441 aaacatgttg agtggcgatg ataaataagg ttaaaagtta ctttatcttt ttggtaacat
     7501 tagtcaaaag agtctgagtc aagatgattc tcagaaaaca aaaagctaga gattcccaat
     7561 tgcggaactc tagcttttta attttgcctc tttctcttat tatatttcag caggttgttg
     7621 gccatgagta tgaatcccat gtcaattctc acttgacgct tacctctcag atgacatctc
     7681 ttataaccca aacaaacctt tatctgccca aagacagatt tcatatcaat cttacgttta
     7741 gcgaaaattt gtctaccctt ggaagataaa agtgcctgat attctttagt ttttaaacac
     7801 tggtaacgtt cattcatata cagtcccttt tgaggggctg attcaggttc ataatcgcag
     7861 tcaacattga tttcaaggct gtttgctttc tatctcccct ttttcatgat atattttcgt
     7921 acaggttctt caatagtttc tatagtaaaa tgaaccaaaa atagtacacg ttgcggtata
     7981 atgttcttgt ggcatattca ttagattttc gtaaacagtt ctctcctatt tgtgagcgaa
     8041 caagtatagt caattgattg tcagtttgaa gaccaagagt cgtaaggcaa aggatatggc
     8101 agaatccatc caagggtggc tggcacaatt tctagtgaac ctctttaaat ctattacgtt
     8161 tgactgtgga aaagagtttt caaaatggaa agatatttcc aatcatcacg atagtgagag
     8221 cttttttgcg aatctaggat gttcaagaca gcggcgtctc aacgaacatt caaatagact
     8281 tttaaggtgt catgacttgc caaagcagac agatttcaac gaagtcagtc aagaatttta
     8341 ggctggacaa aaactcaatt tcaggagaaa atgaaataaa tattcccaca ataaaacgca
     8401 tagtatcaaa gtttttccaa cacctgatat tatgcatttt ttaattttaa agactttttc
     8461 ccagcctcaa gaaatcacat cccacctaaa tcctttggat accaaatacc tcatcaggta
     8521 ttttctgagt tggtaagaat gtctagctta atttgacaaa tggagggcgt taaatccagt
     8581 ttttacagga agtctattta aatattttca cactgacctt acaaaatatg aaataaatta
     8641 tataaagtca ttcccatgac aaagaataac atccctttaa aacagtatct tacccaattt
     8701 tcaggtaaga cttttgatac aaccgtcccc aatacccctc cgcatataga agcaagaaaa
     8761 ataactggaa caggtgctaa atgatactga tttaaacctg taaccacaac aattgtagcc
     8821 aaatgagaca gctgggaaaa gaaaataatt gcaagagaat acatcgttgc ttcttttatc
     8881 gaaatagaaa aaaacaccat caataaagat acattgagcg gaccaccacc aatccctaaa
     8941 aaactagaaa ttaagcccaa tagaagacca caaatcatat agaatcctat cttatcaaat
     9001 tgataagttt ttttaaaatc tgttaaaaca aatgatacaa gtagcatcac aaatagtaaa
     9061 atcatttgaa caatggatac tagccgtact gataactgag ataacaaaac ttgaaaaata
     9121 agatgaccta gaaatcctcc taaaacagaa gaaaaggata ccgtaaaaat caatctccat
     9181 tttatctctt tactttgtga aaatcttttg attgttgaaa taatcgccat tataaaaaca
     9241 gagaaactag aataaaaagc aatatcactg accgaatggt atccaaaact atccataagt
     9301 ggcttaatta taattccacc acccatgcct gatatagaac ccaatccact agctattata
     9361 atgattagaa aataaataat ctcaaccact ttttaagtcc atcctattct ttcaaacatc
     9421 taaaacctag atggctacta gtggaagtag agatacatcc atttctagca gctactcggt
     9481 atcgattaca ataagaacaa tgacataaaa aggaacctcc tctgatagca tactcctcat
     9541 cttgtatccc atattttggc aactcatagt catcttcatt aaaactagct aataaggtat
     9601 atctcggatt gcgacaccat tcccaaacat tcccaatcat ttgatataga ccaaaatcat
     9661 taggtaaaaa ttcatagaca ggagccgttc ctataaatct atctaaggca gtattttcat
     9721 aaggaaatct tccttgccaa gtattggcat gataatatcc accttctaaa agagtatctc
     9781 cccaaggata ttcagattgt cttcctcctc tagcagcata ttcccactgt gcttcagtag
     9841 gtaaagacat tccgctccaa ttacagaaag ccaatgcatc ttctaaagca acatgaacta
     9901 ctggatggtc ttctaaaccc actagattac tgttctcacc gtagggatgt ttccagcaag
     9961 cgttcggaac ttgtaaccac cacggagccc cagcaggatg aggatatccc tccctttctg
    10021 cctctggaac gaacaatata aaaacaaaag accactcttg tcgctcagct agtgttttat
    10081 agcctgtttc tttcacaaat tgagcaaatt cttgattcgt aactggagta tccgcaatgg
    10141 aaaaatcctt tacactaaca gcgacttgag gaccttcaaa atcatctaaa aagccctctt
    10201 cagaatttgt tcccatcata aatgtcccac ccttgatttt tttcattttc atgattgact
    10261 atcccccgtt ttcgttagag ttggcgttat tttagaaagt tcaacaggaa ctaactcttc
    10321 atccacaaca aaaccttctt ctctatatct aagaaagtct actaattttt tcttcatctg
    10381 acgaacaata ggttggtatt tttcgcttgg atacaaatca ttcatttcat gcggatcttt
    10441 tttcatatca aataactgat aatgatttaa aacaggaaac cagataaatt tccactggtc
    10501 tgtcaagata tattgactag aatcttttcc taaagcatgt tcaccatgaa attctgttcg
    10561 ccacccctcg tactgtccaa ataataaatt cttaacactc cgtccatcta gttcatctgt
    10621 agtagttcct cctgccaaat ccacgagtga aggaaaaata tcttgaattt tcactaattg
    10681 cttgattgtt cccctattac cagctatcaa tccagccgga tcgtaaataa acgaaggaat
    10741 gtggatactt ccctgataag gatatccctt tctaaacaga taatgttcac caagctgatc
    10801 tccatgatcc gaaacaaacc agataatcgt atctttatca tgacgaaatt cttttaggga
    10861 agtcaaaaag cgactaattt gatggtctat atgagtaatc aatccaaaat aagcagcaac
    10921 cattcttctt tgatcatctt cctttaattt ccctcttaaa gcataaatag acggaatttg
    10981 cttttctaat acttcccaat tcccgatatg caaatcgaga aattgaggca agcgttccat
    11041 atacatatca aaatagtatt ttgggggatt taatggagca tgtggttttt caaaagacat
    11101 tttgagaaaa aaaggaaccg ttggatctct tctttgtaaa aatgaaatgg actcactcac
    11161 aacccagttt gttggatgta acttctcatc tttatcccaa ggtctagctt cccaagaatt
    11221 acaatccatt ccgtcatcaa tcaaatcaac atcataacca actttaccct ttaaaaaggc
    11281 tagatagtca ctaacataat caaattgact tccataagcc ttatcatact ttctatcaac
    11341 atgtagatac ccatcgtgaa gtaagacatg atcaaaccca agtctctgtc tggaaggaaa
    11401 aacatgcatc ttaccaatac actctgtttg ataacccata tctttaaaga cttttggaag
    11461 agtattagta aaattccaag gcacctcatc ttgataacca acacgtccac ttttatcttg
    11521 gtctaagcca gtcaataaag ctgccctagc aggaacgcaa gaaggaactg gagaataggc
    11581 attttcaaaa ttataaccta cactagccat catatctaat gttggagtgc taactagctt
    11641 atccttacta ttcaaggata aggcgtctgc tctcatttga tctacaacaa tcaaaataat
    11701 atttggctgt tttgtctgaa ccataaaatc tcctttctaa tatggcaaaa gaggcacaag
    11761 aagatatcta cctttactgc acccctttct atatcaatct ctctatataa agcaataaca
    11821 ttcttgttat gttttataga acaatgaact aaaatatgac taaatcgatt aggaaattca
    11881 aatcattttc tagtactgtt ttagaagtta cagtgtacta ttccaacttc aacaaactat
    11941 aaaccttggt ctaataacaa ttttagtgga gataagaaat cctacaccta actcatctta
    12001 cacgtaatct atttctattt tatcacaaaa aacgcaagta agaccattaa ctcaattcag
    12061 ttttatctgc cattttcaca aatgggaaat aagtcaagac actaataatc aaacaaacaa
    12121 ctgataagat gatggcacgc caatcaaatg ctgtagagaa gaaaccatat aaaattggag
    12181 gcattaccca agtaacattt tgtgtaacag gtgaaacaag accccagctt gttgcccagt
    12241 aagctaccgt tgccatgaaa accgggctaa gtacaaatgg tataaatagc aaaggattca
    12301 agacaactgg taaaccataa ttgaccggct caccaatatt aaacagaact ggtgctagac
    12361 caagtttagc aacttttcga taatgactgt ttcttgaaaa aattaaaata gcaagtacca
    12421 atcctaatcc tccaaaccag acaaacgccc caaaagaccc acttgtccat atataaggaa
    12481 tcggttcacc tttttggaaa gcatccagat tcgctaacat agcaactcca aacagccctt
    12541 ccatgatggg agccaataca tttcctccat ggagaccaaa aaaccagaat aacttattta
    12601 aaaagatcat cagaataact gcaaagaaac tttgagacaa acctagtaat ggcgtttgta
    12661 acaccttgta aacccaatca atcaataagt cattgctaag taaatggaaa acataagtca
    12721 agatggctac tatatacatc gccataaatc ctggaatgat agaagtgaac ggcttagcaa
    12781 tcgcaggggg aactgaatct ggtaacttga ttacccagtt ctttttcatt actttacaga
    12841 aaataataga ggctaaaaat ccaatcatca tggctgtaaa gtagcctctg gcattaatat
    12901 ggtttcctgg aatcacattc ccaatagtta ccatcagatt tttaccatca aatgctagat
    12961 tatcaattcc ttgtaagatc tgatctaatt tcacatctcc tacatttgcc aaagggaaac
    13021 tctttgtaac tgtacttcca atcgaaatga caaacgaagc aagtgatacc aaaccagcag
    13081 aaactgtatc aaccttgtaa atcttagcga tattcactcc caagcaatag atgaacaaca
    13141 aagaaacaat tggtatactt cccttgaata ccaaattatt gatgtcaaca agccactgaa
    13201 aggttttcgt aatactttct aggtgaaatt gttgtggtaa atccactaga aaagcattta
    13261 ataacaaagc aatggaacct gtcataataa caggcatagt ccccacaaat gaatcacgta
    13321 aagcaactaa aaacttctga ttcccaactt tcattgcaat tggagaaagt ttttcttgca
    13381 ttttatccaa cattgtattc atactaaact cctaattttt ttcaaatcgt tcgtatactt
    13441 ctaccacttc tttcgccaag tcaacaaaag tcagactcgt cattaaatga tcttgcgcgt
    13501 gtaccatcaa gaggctaatt gatgtttctt ccccctgtgc ctctcttgtc aacatttctg
    13561 tttgagcctt atgcgcctgt aataaggcag cattcgcatc agctaatctt cgattggctt
    13621 tagagaaatc cccttttttt gctgcctgaa tagcctccat agcattactt ttggcttccc
    13681 caccatacat aattagcccc attacagatt ctaaattact ttcatccata acattctcct
    13741 caatcttagt ctaataaact ttcagctaaa tctaaaactt tagaaccatt catcattccg
    13801 taatctgtca tcggaataac cgccacagga atctgtctat cttttagttt ttcttgaaag
    13861 tcccctagta aatagcgaac ttgggggcct aaaagcaaca catttacttc ttttgttgct
    13921 acaatttctt ctgcttcagg agctggaact gcaaaaattt ctgcatccaa ccccttatct
    13981 tctgctgcct tttgcatctt tgtcactagc agacttgtac tcatacctgc tgcacacgct
    14041 aacataattg ttactttagc catagcttac tccttttatt ttattgtcaa tgttactgtt
    14101 tttcgatcaa ctttagactc ataatctaaa tgtttgggac gactagtata atgcaaatta
    14161 taaactcctg gaggcatttg tgaaatcttt tctttttcag ttttattgcg aattaataaa
    14221 tctaccgaag tattccctcc aaagttatta aacataggtt cattttcaat agaataatct
    14281 aactcatatc cactattagt tgtaattcct tttaataaat caggaacatc tcctctgttt
    14341 attactatat ccttagcgcc atttattttg ggagattgac tataatactc ttcagcttga
    14401 tgttgttgta aatcatttct agagtaagaa acataatcaa ctacaaattc agtccctgat
    14461 aaattattgt ccactacccc aggccaactt cctcccatcg ctaaatttaa ctgaacatac
    14521 tgaggtctat taaaaatctt tttcgctata ttatctgatc cataatatac ttttctaaca
    14581 atatgattgt caaccatcca tacaatataa tctttatacc aatcaattga aaaagtatga
    14641 tacgaatcat taaagtttcc actcgataat ttaaaggctg taccacgtcc tgcaaatttt
    14701 ccatcatcat tatccgactg tccataatga agcgtttgat aaactgtctt attcccactt
    14761 ccatttgaat ttcgttcacc aactaattcc attatatcta tctcacctgt tgacggccat
    14821 cctcgtccct gaacaggatt aatcttccca tcaagtgtaa aatccgatcc aagagtccag
    14881 aaagcaggaa aaactccttg acctttcggt aattttgcac gcatctctaa tttaccataa
    14941 agaaattcta ctttcccatg tgttctaaca cttcctgaat tatatacaac ctttctgtga
    15001 ttgtttcttg ggttaaaata ctgatcttcc ttagagcgat tcgtagctct aagaactaaa
    15061 tttcccgaac gtagaaaaac attctcatca cttcttacat aatgttgctg ttcccaacca
    15121 cgaattgatc ctaattcata tccccaatat tttttattta attgttcgcc atcaaaatca
    15181 tctctccaaa ttttcttata tgaatttcct ttagacagtt gatacatctc tacattatca
    15241 ataaaaatat tagatttttt tgtagtatcg tcttctgacc atttcactaa ttgaatcaaa
    15301 actttatcgt gtttaccgga attgaaagaa aacatgtatt ttttccattc ggttgtatta
    15361 actgtttgat caacagcttc tccaatgtta ttttgaacaa tctctccttg cttattatta
    15421 tcaaaccatc ttgcggtaaa atatccctct gctccactaa tatctacttt ggcaaaagca
    15481 gatactaaat aatcttcatt aggttctata tcaataactt gtccaatata tccatctgct
    15541 ctattatcat taattgcagt agaaggaatc atacctgagt aatgtccgtt actataactc
    15601 tcatttgaat taattattcc cctatttcta gagttccaaa acagctctcc ttgctcaaaa
    15661 tttgaatttt ttattaaatt ttcattagca aaaactttca catgaataaa tattaataaa
    15721 aataatataa ataaacttga aattaatttc ttattcttca ttttatcacc tatttactga
    15781 cctagccaag cgagatactg tatgtctcac tcctctaatt gccttgctca atgcataaat
    15841 attatcgact gttgccagtc ccccatatcc tgcgtcacct atatgttgaa tatcaactcc
    15901 acaaatttta tttctaagtg caatttcctt gatagtatct gtatcagatg tttcttggct
    15961 agtaccaata gcactcagta ctagcccacc cttactatga acgagatcaa cgacttcacg
    16021 caactcttgg tcatgaaagg ctggaacggt tccaactgct ggaacaagta tcacatccgc
    16081 acctgcttcc aacaattgct ctgcgacaga aagctctgcc acaggctcat tcactcctgc
    16141 cccgtgcatc ttacctgcaa taatcaaacc agaaaagttt tccttagcag tttgaacagc
    16201 cttaatgatt tctcgattgc taactcctgt tccaggattt ccagtcaaac agacaaagtc
    16261 aaaacctaac tcctctattc gattcaatgt ttcaacacta gcaacacgac ctgcaacaat
    16321 ttcctgtgtt tcctctagca tctttgcaga tgggtcaatc ggttccaaat ttacaccaat
    16381 tggacaagca acaagctggt gtaagcgatg aataacatca tcacctgaac tatccaaagc
    16441 ataaatttta ggctcaaaaa catcaacaca attcaataaa atcatatcag ctccaaaagc
    16501 tctagcaatt tcagaattag ttatatcccc aacaaatgtc tcacgagtaa ctacattttc
    16561 agatagaaca actctacctt cacttgctaa aatactttgt tttaattctt cagcattcat
    16621 ctgtaatatc tcagatggat ttgcactaat taaacgtttc attctcaatc ctccaataac
    16681 ttaaaccgtt tttcaatagc tattacaaat ggtaaataaa gtaagacatc caaaacaatc
    16741 aatacaattt gtaataatga accagaaata cttcctgtag caagtaaacc acttataaca
    16801 ggtggcatag tccaacttgg atctgtataa gttagcggaa ccaaacctga tgccattgct
    16861 ccccacgcta ctagtaagtt aaacattgga gctaagataa atggaactag taacaaaatg
    16921 ttcaaaacaa taggaacgcc aaacattgct ggttcattta tattaaataa tccaggtata
    16981 acagttatag gtgccaaagt ttttagttgt ttactagctt tcttcttatg tgctaaatat
    17041 cctaacgcaa gaactaaacc tatggttgca ccaccgccac ctatgaatac aaaattatcc
    17101 ataaatacgc tagtaaaaat atttggaaga gtttctccag tttgataagc tactttattt
    17161 gcatctagat tagctaacca taacggtttc ataactgcat taacaacatt tcctccgtgt
    17221 aatcctacaa accaaaaact actattaagg aaaattaaga taagaagacc aataacatta
    17281 tttcctaaaa gtccaagtgg acctcccaaa gctccttgag caatttcatg aagattaggt
    17341 aaacttaatt tatctaaagt tgcataaaca atcaaccaac caacaatagt cactgcacca
    17401 ggaataatgg cactaaagct tttagatact gctggtggaa caccatccgg catttttatc
    17461 tgtatattat gatttataaa ccattggtag atatagccat taatcaatcc taaaatcata
    17521 gcaacaaata aaccttttga tgccatgaaa gcggtaggca ttcctgctcc agcctctcct
    17581 gtaatgaaag gcgtaactgt aataaaagat gataatgaca caataccagc aggaatacca
    17641 tcaactttgt attgtctagc cataaagtaa gcgataccaa aactagctac aagaccaagt
    17701 aatccaaaac tactatcaac acccttccat aaatagtcag caacaccaat atcacctaga
    17761 tatttttccc atcctggaat aggaaaactt gcaataacca ttagtaatga acctatcaac
    17821 aataaaggta tagttagagt aataccgtct cgaatagaaa ccaacgcttt attattaccc
    17881 aatctagccg ctactggaag taacttttct tgtaataatt tttccataac cttttcctct
    17941 taaatatatt ttattatcaa aagttatcaa ttatctttat tttttgacgt caagttatta
    18001 tttgattatc ttttgttatt tatattttac aactataaga aagccttgtc aaggatttgt
    18061 gtaaatattt gattattttt tattatcaat atataataaa aagagaccag taagcaatga
    18121 aaagcttaaa aagattaaca tctacattta tccatagcaa aaaatcatag gattttaaga
    18181 atctgacaac taggaagaaa actaatatga ccttatctaa gaaacaatta caactaagag
    18241 ctaaaatact ggaaacagtt tacacattag gtcccatttc acgaattgaa atcgctacta
    18301 aaacaggaat aacacctgca acaactagca gtatcacaaa tgatctgatt aaagaaaata
    18361 ttctcttaga acttggtgaa gacgaacacg atacaagcgt agggagaaaa aaaatcctgc
    18421 tagacattca agctaaacga ttttactaca ttggttgtga actatctgaa aaacatttca
    18481 cttttgcttt aggagataat ctaggaaata tcttaaagga agagaaagaa attgttacta
    18541 aacagttaat ccaagaaaag ggaaatcaac tcattaacca gacactaaag caattcttaa
    18601 ataactgctc tgattatgaa atagaagcaa ttggaatcgc gctacctggt cgctatttag
    18661 atgattataa aataacaaca aacaatcctt tatggcaaca tatcgactta gaaatgattc
    18721 aatcccactt tgataagcct ttgtttttct ctaacaatgt taactgtatg gctataggta
    18781 aacgcctatt tagtcgccaa cagaatgacc ctaattttgc ttattttcat tttgctagag
    18841 gtatgcactg ttcttatatc tacgacggaa acatttatgg gaaaggaaat ctaatgattg
    18901 gagaaatagg gcatacagtt gtttcatctg agggagaaga atgtagctgc gggcgcaagg
    18961 gatgcttaca aacttttgct ggagaatctt ggttaatcaa aaaatcaaaa attctatatc
    19021 atcaatctcc ctattctcta cttcctagtt tagtcaaaaa tgccgatgat attgatatcc
    19081 aagttatttt aaccgcttat caattaggtg acactggaat aatcacactt atccatcaag
    19141 ccttactcta tcttagtcaa accattttaa atatcagtat gatgattgac tctcaaaaaa
    19201 tctacctaca tagtccttta ctaacaaatc aacacatcat ccaaaaacta tatagtgaaa
    19261 tgaactacaa acccaaactg ctctataatc gcctacctga agtcattatt gaaccttaca
    19321 atgattttac agccgcacac tcagctattg cactttgttt gtatcataca attctacatt
    19381 cttaattttc tattacattt aataaatagg ctaaaaagag ggagtatatc ataaaaagcg
    19441 aataaacctg ttttctgaaa atcagaattc tgttttgttc gctttcttta tatttggaat
    19501 tatactccta tctccccttt ttcataatgt atagtgaaat gaaataataa caggacgaat
    19561 cgatcgggac agtcaaatcg atttctaaca atgttttaga aatagaggtg tactattcta
    19621 gtttcaatcc actatatttt cgtacaggtg cttcaaccat ttgaacgatt tcaaatcctt
    19681 ctttttggta aagattctga gctctttgat ttgcctcgaa gacatttaga gaaatactat
    19741 ctatatcttc attttcaaag gccaaactaa caaatttcct taaagcctgg ctacctaagt
    19801 cttgctcctg tttctggggg ttgataaaaa atctcccgat atgaagattg ctgtcttcta
    19861 gcctgatttt ctggataagt cccacaaact cttgttcatc aaagattgaa aagactcctt
    19921 ccaaggcttg aaggggcagt agaaaaggaa tccttggtcc catccattgt tcttgaaagg
    19981 atttgcctag ggagttggac cactggcata caaattgagc gttttctata ctcacctttt
    20041 cttcaaaacg aattgtcatc ttttcctcac catcttatct atgtttctcc attatactat
    20101 ttctcccatt ttttacgaat agataagtat gattgatttt tatttttttc tcgtcgggag
    20161 cattctcgct tcctttcttg gtttggtcat tgaccgtttt ccagagcaat ccattatcag
    20221 ttcagccagt cactgcgatt cctgtcagac tcccttgcgt cccttagatt tgattccgat
    20281 tctctcacag gtcttcaatc gctttcgctg tcgctactgc aaagttcgct atcctgtctg
    20341 gtatgccctc tttgaactag gcttaggact cctctttctg ctttactctt gggaattgct
    20401 ttccttgggg caagtcgtcc taatcaccgc tggtttgacc ttgggtatat acgactttca
    20461 ccatcaggaa tatcccttac tggtctggat gactttccac ctaatcctaa tagcttcctc
    20521 tggctggaat ctggtcatgg tctccttcct catacttgga attttggctc attttattga
    20581 tatccgcatg ggtgcagggg atttcctctt tttagcttct tgtgctctcg tctttagcgt
    20641 aacggagtta ctgatcttga ttcagttcgc ttctgcgacg ggtatcctgg cctttctcct
    20701 gcaaaagaaa aaggaaagac ttcctttcgt gcctttcctc ttacttgcta cttgtgtgat
    20761 tatttttggt aagctactac ttgtttgata aattccaatt tctgccatat gtactccatg
    20821 aaattatttc acagttaaat tataaattat ttcttttgta caaagggatg atgttatcaa
    20881 atcgatctgt tcttctatct tcttgatact gatcaaaaaa tttcatttcg actgaaaata
    20941 tttcgcttat aaactgtaaa cgaatacttt gtttagacat tatagtcgct agactgacta
    21001 gatgattact caaaacgacg tccagaatac tctttacttt gcttggtttt ttaacaaaaa
    21061 tttgatcatc caaaggttca atcattttgt aacctttttg cgcaatttga cgataaaagt
    21121 aagaatgttg ctttggagtc aataatccta acttaaaagc tcgatactct aaagcctgta
    21181 tcgaaacatt caaatccgac ttcaataaaa tataactatc aggattgctg acacgcttgc
    21241 caaccctctc ttcaaatttg actaaaaact cttcttttgg caataaaaaa catgatgcaa
    21301 aataatttgc ttcttgctcc aaacgatcgc catcttcatt catatcttta tatttatgta
    21361 aaagaatatg tcctagctca tgagctaaat caaaatttcg acgtacagat gatttattcg
    21421 ttcccaacac aatataaggt cttcccaatt ttgaccatgc gctataagca tcagcttggc
    21481 cattaattaa tcgttccacg atatagatgc ctgaacgttc taatttataa agcaaatcat
    21541 gattatcttt tgaaatacct aatttttccc tggcataaag agccaattcc tcaatggatt
    21601 ctcccttatg ataagattca ctcactacat tacttaggtc atgaattgta atattaggta
    21661 taattacaaa actttcaaaa taatcaatca aactatctac cttatgtaaa tacatagttt
    21721 gaatatctat tgttttccgg gttgctaggt ctgcatttct aaaggcaatt acagaagaat
    21781 caaatcgaat gctctcttct tcctgttcaa aataagttaa atcaacatga aattggttgg
    21841 ccaaatgcat tttggttgat aatttaggtt tcgtttcgtt ggactcaaac tgccaaatgg
    21901 cttgttccgt taaattaatt ctctgagcta attctgctct acttaaacca tttaacagcc
    21961 gtaattcttt caatacccga ccattaaaca tttacatact ccttactact tttgaccttc
    22021 ttgtttttct attcttggaa taatttcaaa atcttctgtt tccgataatt ctgaaaaatt
    22081 aggaatatct tgatatttag cttcttcgaa atggtacgaa cttgattgaa tatactcaga
    22141 caaatcttga atcaagtgta actgaccagt tcgtgcatca ggcataacaa catctacaga
    22201 tataatattg ttttctgagt ccgcctcata agttaaaatc ataaattttt cgatattcga
    22261 atttttagta gcttgttcaa tttcttgaat catttcatca gaaactaact ccatctgaat
    22321 tggaaaggaa tgactatctt catcattttt gtaggaagaa tgttgattaa gataaagtgt
    22381 attcatctga gcatattcaa ataagtagcc actcttattt ttttgtacca aaggaaattg
    22441 gttcgtaagt cgcttcttac cctttataat taacaatact ttcccatatt tttctgtgtt
    22501 tgtttcaaat tctaaatatc cccaagtctg tcctgctaat tgtaatttat actcaaacaa
    22561 atctgctgat gcaaatgcag tatcaatatg attaggtcgc gtccatgcat aaccattcga
    22621 cactatcatt gtctctcttt tttctagacg ttcatctaca taatcttttt gccctttcat
    22681 caaagtatct acaatttttt gtgcctcaag cgaatcaaag agatcctgat tcaacataat
    22741 tcttcctcct ccaaatactt tttaatgaat tatatcattt tcttaaagaa attactacaa
    22801 taattagctt tttcttaaag ttctgtgtca gagtaattta gaaaattata tcttctatag
    22861 taaaatcaat taaaaactga acaaatttat tgggaaattc aaatcacttt ctaaaaatat
    22921 tttaggaacc gtagtgtaat attccagatt caatttacta taaaactagc ctttctcctg
    22981 caaaagaaaa aggaaagact tcctttcgtg cctttcctct tacttgctac ttgtttaatt
    23041 atttttggta agctactgct tgtttgataa agtcctgaat cggctctcct tggtggagag
    23101 cttttactat tttcgaaccg acgataacac catctgacac cgcattgaag cgttccagat
    23161 cggcttgact agatacacca aaacctgtca agactgggat gtcggccact tgatgaagtt
    23221 gcgccaagtg cttgtccaaa tctgcacggt aattgcctga tttccctgtt accccattga
    23281 tggcaacggc atagacgaat ccctccgccc cttcaatcaa ctctttctgg cgctcaattc
    23341 ctgtggtcaa gcttactaaa ggaatcaagg cgatatctgt atctgccaaa aatggttcta
    23401 caaagttggc atgttcatga ggcaggtctg ggataatcaa gcccttcaca gctgtatcag
    23461 ccagatcttt gacaaagttc tccacaccgt actgaaagag ggggttgaag taggtcatga
    23521 tgaccagtgg aatctctgtt tcaatggttt tcaaggtttc aactaaagcc tgggtagagg
    23581 tcccgtgggc taaactgcgc aagccagctt cttcgataac aggtccatct gcaacagggt
    23641 ctgaaaaggg aatacccact tcaattgcag agacacccaa atcttctaaa aagtgaattg
    23701 tttcagcaag accatccaaa cctttttcgt ggtcaccagc catgatatag ggaacaaaaa
    23761 ttccttttcc agctgcttta atagcattta atttttttgt tagtgtctta ggcatgagct
    23821 tctcccttct ttgctgcatc tgcttccaag cggtctttta cttgaaccac atccttgtcc
    23881 ccacgacctg ataggcatac aatcatagac ttttctggtc caagttcttt ggccaatttc
    23941 accgcaaagg cgatagcatg gctagattcc aaagctggga taatcccttc cacacgagac
    24001 aagagttgga atccttccaa ggcttcttcg tctgtcacag ggacatagct ggcacgttta
    24061 atatcgtggt agtgagaatg ctctggaccg ataccaggat agtccaaacc tgctgagata
    24121 gagaaggctt caagaatttg accatgggca tcttggagca catccatgag ggaaccgtga
    24181 aggacacctg gacgaccctt ggtcaaggta gctgcgtggt gctccgtatc cacaccaaat
    24241 ccagccgctt cagctccata catggctact gactcatctt ctacaaaggg atggaagaga
    24301 ccgatggcat tcgacccacc accaacacag gctactaggg catctggcag attttgtcct
    24361 gtcaagtcac ggtactgttg tttagcctct cgaccaatga cactttggaa gtcacgaaca
    24421 atttctggaa atggatgagg ccccaaggca gaaccaagga tatagtgggt atcatctata
    24481 ttagccaccc atgaacgaag ggctgcattg accgcatcct tgagcacgcg cgaaccatct
    24541 gtcacggcct cgaccttagc tcccaaaagc tccatacgga agacattgag ggcttggcgt
    24601 ttgacatctt cctcacccat gtagatggta cattccatgt taaagagggc cgcagcagtt
    24661 gcagttgcca caccgtgctg accagcacca gtttctgcga taattttctt tttacccatg
    24721 cgtttggcaa gccaaacttg tcccaaggca ttgttaatct tgtgggctcc tgtatggtta
    24781 aggtcttccc gtttgagata aatcttggct ccgccgatat gctgggtcaa gttttttgcg
    24841 taataaagag gagtttcacg tcctacgtac tggcgcaaaa gctggtttaa ttcctcttgg
    24901 aaacttgggt ctgcctgact ttcacggtag gccttctcca actccaaaac tgctgtcatc
    24961 aatgtttctg ggacaaaacg tccgccgaat tttccgtaaa atccatcttt atttggttcc
    25021 tgatatgcca tgctttaccc tctctataaa tcttctaatc ttttcatgat ctttttgtcc
    25081 atctgtctcc actccgctcg atacatctac tgcataggga gtaaaatgtt gaattgcttt
    25141 tactacatta tcttcattaa ggccacctgc gataaagaag ggctgtgcta gtccagtcgt
    25201 atccagttga ccccaatcaa aggactgacc acttcctgcc acaggggcat caaagagtag
    25261 ataatctgcc tgagaattgg ggacatgccc atttccatct acctgcacag cctgaatact
    25321 ggcacaaggc aaattctcaa ataaatcagc tgccacctga ccgtgaactt gaaccaagtc
    25381 caagccaact ttgtcaatcg cttccagcag ttctacccga cttggtgaaa caaatactcc
    25441 aacctttttc acatctgcag gaataagctt tgccaactca gctgcctctt ctaaagtcac
    25501 ctgtctttta ctaggtgcaa agacaaaacc gatatagtcg gctcctgctg aaacggctgt
    25561 ttccaccgct tctttggtcg atagtccaca aattttaacc tttgtcaatc tgcaactcct
    25621 tgattctctg ggccacattt tctgcctgca taagagctgt ccctaccaaa attccgttaa
    25681 agtatggggc tagtcgttcc gcatcctgcc ctgtgaaaat ggcagattca gaaatgtaat
    25741 agcgaccttc ctcaaagtaa ggggctaaat ctacactggt ctgcaagtcg acctcaaagg
    25801 tagtcaagtt gcggttgttg accccgataa tctcagcacc aagtctgtgg gctacctcta
    25861 gttcagctag attgtgagtc tccactaaga cttccagacc aagctctgtc gcgtagtcat
    25921 acagttcctt gaggcgttct tcggacaagg ctgccacaat aagcaagata actgtcgcac
    25981 ctgtattgcg agcgcggatg atttgctttt catctatgat aaagtctttg ttgagcgtcg
    26041 gaatctctac ctgactggaa atttcccgta gataatccaa atgcccttta aagaaaacct
    26101 catctgtcaa caccgaaatc atcactgctc cgttttcttc ataagtctgg gcctgttgca
    26161 caatatccac atcgagattg atatctccca aactagggct agctttcttg acctcagcga
    26221 ttacctgcaa gcagtcctga tgattcttca aaaattctgc caagcgatag gtctggcgca
    26281 gaggctggat ttgctccagc ttcatctgct ccacctcacg cgccttctgc tctaagattc
    26341 gtgctaaaaa ttcctgactc atttttggta ctcctgtaac agtctgagtt tttcaagggc
    26401 cttgcctcta gcaatcactt gacgggccaa ggcaactcct tccttgatgc tatcaatctt
    26461 accattagca tagaaaccaa gaccagcatt caagactgtc gtttccaaga atggacttgc
    26521 ttcgtttttc agaacgctaa gcaaaatttc tgcattttcc tgagcattcc caccacgaat
    26581 atcttccata gcatagtctt ccattcccaa atcctctgga gtaaagcttg acaagctgat
    26641 ttcgccattt tcaagaagtg caatcttggt tgttccgttc aagccagctt catccaaccc
    26701 ttctggtcca gcaaccacga tggcacgttt gcgacccata tttttcaaaa cctgagctgt
    26761 actttctagg agttctggac gactaattcc aagaagctgt gtttctaaag ccattggatg
    26821 aatcagtgga ccagtcaagt tcataatcgt tggaattccc aattccaaac gagctggcat
    26881 gatgtatttc atagctgggt gcatattttt agcgaagaga aagacgattc cagttttatc
    26941 aaagacctta cctagttcag ctggtttgag gtcaagattg attcccaagg cttcgaggac
    27001 atctgcggaa ccagatttag aagaaatcga gcggttacca tgcttggcca tgtgaatacc
    27061 gccaccagcc aagacaaagg ctgcagttgt ggaaatatta aaactgaaag acttgtcccc
    27121 acctgtacca cagttgtcca tagcatcatg aatctcagtt ggaatatgct gggcatgtcc
    27181 tctcatgact tgggcaatgg ctgtacgttc ttcaggtgtt tcccccttca tcttaagagc
    27241 taagaggaga gaagcaatct gcgcttcagt tacacgccca gttacgatac gctcaatgac
    27301 atccgtcatt tccacacctg ataaattttc aaattttgct agtttttcaa taatctcttt
    27361 catcctagtt tcctcacttt acaaccttct cgataaaatt ccgaatagaa gacaagccgt
    27421 ctggcgttcc aatgctctct ggatggtact ggaagccata aatcggtagg tttttatgtt
    27481 gaatccccat gatggcttgg tcatcagtcg aacgagctgt cacttcaaag tcttctggca
    27541 tttcctcaat caaaatactg tgataacgca tgaccgcacg tccatcctca ataccttgat
    27601 acaaaacaga tggcgcttca aagttgatat tgctctgttt cccatgcatg acttttggag
    27661 ccaaacctag cttaccacca aagacttctg caatggcttg gtgacccaaa caaatcccta
    27721 gaatcggctt cttgcctgca aaatcacaaa tcatgtcttc catctttcca gcatcaactg
    27781 gccaaccagg accaggagaa aagaccagac catctgcttt ttcagcttct tcatacagct
    27841 tggaatcatc atttctcaaa acctgaactt ctgcaaaatt cccaatgtat tgggccaagt
    27901 tataggtaaa agaatcatag ttgtcaatca ataaaatcat ggtcttagtt ctccaattct
    27961 agtcatagat tttgctttgt taatggtttc ttggtattcg ttttgggcga tagagtcgta
    28021 gacaatccct gccccagcct gcacataggc tctttgattt ttgagaatca tggttcggat
    28081 ggcaatggcc aaatccatat cacccgtcgc agacaagtag ccgattgctc ctgcatatac
    28141 gctccgtttt tccgtttcca gttcatagat gcgtctcata gctcgaattt ttggtgctcc
    28201 agaaacggtt ccagcaggaa gcgttgcttt caaggcatcc atggcagtga gttctgcaag
    28261 caaacgtccc ttgaccacac tggtcaaatg catgacgtag cggaagagct ccacctccat
    28321 atacttagta acttggacac tggccgtttc agagatgcgg ccaatatcgt tacgccccaa
    28381 gtctaccaac attcgatgtt ctgctgtttc cttctcatca gagaggaggt cagtcgccaa
    28441 ggccttgtct tcttcatccg tagcccctct tggtcgcgtc cctgcaatcg gattggttgt
    28501 cacgatgcca tttttgacag aaaccaaact ttctggacta gctccgatga tttgataatc
    28561 cccaaaatca tagaaataaa ggtaattaga tggattagtc acgcggagat ttctgtagaa
    28621 gtcaaatgga tttccagtaa cttctgctga gaaacgctgg ctgagtacac attggaacat
    28681 atctccgtta cgaatcaagt cacgagctgt ttctaccatt ccctcaaact tatgtggagc
    28741 gatatgcggt ttgaagtcaa gtggtgataa atccaagtct tcaaattcat ttggagcagg
    28801 aatgcgtaat tcctcaagca cttggttcaa ggatttttcc aaggcctctt gactgcgctc
    28861 actataaagt gcatcctcta tgacatgtat cttctccttc ttgtggtcaa agaccatata
    28921 gctctcatag acaaagaaat gcatgtctgg cgtcccaatt gtatcctcag ggatttgacc
    28981 aatttcttca taaagcgaaa tcatatcgta accaacaaaa ccaatggctc ccccaccaaa
    29041 agggaggtct gaatggtgct ggctcttatg agtcacttca taaaggaaat ccaagggatc
    29101 ccgatcaatc gcttgaccat tttgatagag aactccattt tcaaacttaa tctcaaaaac
    29161 tggattatag gctaggatag aaaaacgagc tgtttccttg tctctcggaa tactctctaa
    29221 aataacctta tgttgcccct ttaagcgcat ataagccaag attggtgata agacatctcc
    29281 atgaatgatt cgttccattg tcatttccct ttcagttcta attctagttc gtggcgactg
    29341 tatgaaaaat ccccacgcaa aataacttgc gtgaggacga aattcgcggt gccacctcaa
    29401 ttataggatt tctcctatct ctcattcctg tctcagatat ctcctgtaac aggctgtgcg
    29461 ataaagggca ctcccttgag aatgatgttt tcttctctcg tttcagatga acccaacttt
    29521 acagctttct ctgcttgttt tcagcaacca caagctctct gtgagagaaa agactgtaat
    29581 ttttccatct attatttttt agcttctagt aatctgcaat cgcagctagg tccttgcctc
    29641 cacgaccaga gacattgatg aagagatgtt catctcggta cacctttata ctcttcgaaa
    29701 atctcttcaa accgcgtcaa cgtcgccttg ccgtaggtat ggttactgac ttcgtcagtt
    29761 ctatctgcaa cctcaaaaca gtgttttgag ctgacttcgt cagttctatc cacaacctca
    29821 aaacagtgtt ttgagcaacc tgcggctagt ttcctagttt gctctttgat tttcattgag
    29881 tattactagc ttttttcgta ttagtccagc ctttttgttt acttttagta ggaggcaagg
    29941 agctgtagat agaactcaag ttcatcaaag cgacttaagg ccctaataaa agataaacca
    30001 aacgacggat agaaaaaagc ccacacacag aatatacttc cgtgtgaggg cgttggtaac
    30061 gcggtgccac ctcaattata aagggactat ccctttacat ctctgccttg tttaacaaca
    30121 agctgcactg taaggtgtgc gcaccgaatt ttcattgttt caaattcatt ttcaaaatca
    30181 gcccactttc actacttcca accacctatt cacaatcacc acaggctccc tgaagatcaa
    30241 aaatagttac ttttctgatt tgttgaactt attttaatac tttgtttttt ctttgtcaag
    30301 acttttttac gatttttttg atatcattcg aatgtgacca tatcttcctt agatcgaaca
    30361 tgaacatgtc ccacttgtta gaaattggat ccaactcaat agaaactgaa tggaggctaa
    30421 acagaactta ttttagaaca ctccatcttt tccactagga ttttcaagaa ttaaacaata
    30481 ctagaaactc tgtctcctaa caaatttagg agaaacttca acagatgtga cactttcccc
    30541 tttaataatt gctaaaacac cttctatcat ttctttagcc aatttaacat aattgggagc
    30601 aattgtagac aaagctggag tataatactg agaaatagga atattatcaa atccaatgat
    30661 agaaatatca tctggaataa gaattccttt ctcatagcac gcacgaatca agccctgaac
    30721 cttttcatct cctgaaacaa aaataatgtc cggataattt tgggtagtca agtgctgcat
    30781 tgcataagaa taaactgaat caattgtaga taagccataa atgactttta aatccataaa
    30841 gtaattttta tcattcagaa aagaacgcac acctctttca cgatccttat taacatggga
    30901 ttctcctccc ataagcaacc acatattttt aaatttttct tcagttacag ctttcatcat
    30961 atcataagta gcttgaaaat tattattaga tacatagact actccagacg tttgagattc
    31021 accgaaaaca agaaaaggca tatggttctt ctttaaatac tgaattctga tatcatctac
    31081 actttcataa aaaacaataa caccatctac taggctacct gtgcttgata taattgaatt
    31141 actaattgta tcctcctctc caaagtactc aactatagca ttaacaccaa attctttaca
    31201 cgtccgtaac actttatcta acagcgtatg aaaccaaatt aaaggaaaag agtcgatttt
    31261 ttttacagaa atcaatatat ttatagcttc ttttttagtt aaattttttg catacgcatt
    31321 tggaatatac gacaattcct ctataacttt ttgaatcgct tgataagttt cttctttaac
    31381 atttactcca ccattaataa ctcgtgaaac tgtttttgga gaaaaacctg ataaacgtgc
    31441 aatatcataa atagttacct ttttcccatt tatatttttc atttcagtcc tccattacga
    31501 acattctaat attactatac aatatttaat tttttttaac aagagaattt agtaaattat
    31561 ttaagatcca caaattcaca aaattaattt tacaaatatt cttccccttc aaaaaaattt
    31621 aaattgcatt tcacaccttt atttttaaga atgtttccaa cttcacgaca aataaattca
    31681 tatgagaaaa aactgccata aaattgtaga ttaacttttt cagtaaaatg tgtaggattt
    31741 ataaaaacat ataatagcct gtcaatgtaa cattttaaca tagagttaat tttttcttta
    31801 aagataacat ttgttatcaa ctcatcagga ggtaaatgaa aggcaaacac catttcacaa
    31861 atatcataaa aagaaataaa tttgtatact tgtatcaaac aattattatc aaaatattct
    31921 attttaccta aatcaaaatt gattttataa tctttcataa aaacctctga gcaaaaatct
    31981 actcaaaaat tagatgatta aaacatctaa aaaacaaaag gacaaaaaca tctgtccctt
    32041 tgtttactaa atttcagcta atttcttcga cataaataac acctacaata ttagcaattt
    32101 cttccatcag tcgaagatgt tcaaatctac ctgataattc cagagtaata aatgacgcta
    32161 tttttttatc tggaacatca aagtattcaa ttctgtcaga attaacatct ccaaacgctg
    32221 ttcttgaatc ggtcattctg ataccatttt ctgcacaata aaccaataca cgattatagg
    32281 cttctgtaga tttaaccact atatacaatt caatcatttt agaacgattt tgtagatatt
    32341 tttttagtgg ttggaacatg gatatcacac cccaaacaga aatggctact aaaagagctc
    32401 cctcataaaa acctactcca atagctaatc caattcctgc cgaagcccaa atgcctgctg
    32461 cagttgtcag acctgtaatt ttctttttat ctgtaataag aatcgttcca gcgcctagaa
    32521 aacccacacc tgatataact tgagctccta atcgtgtagg atctcctgtc ccaaatttat
    32581 aagatacgta ttcattcgtc atcataatca aacatgcagc tagacaaaca atactataag
    32641 ttcggatgcc tgcaggctgg gatttgctcc ctctctctaa accaattata ctaccaatga
    32701 ctactgataa aacaatcctg acaactattt caatatttga taacccaaga ctagtggctg
    32761 tcatgattat ttccttactt tacgccccgg tctttgtgtg aagtataata ccgttccaga
    32821 aataatcatc agaacaattg tataaacaaa taccagagct tgtgcattag atgttgctgt
    32881 ttcatcacct gcagatcgaa tcgtaatacc taatggttga gctaggggat ggtaaaggaa
    32941 tacagataag tcgaagtcag ttaataaaga gttaaagttt aaagcaataa cagagagaac
    33001 aaccggtaaa ataaatggaa tgataacctt catcatagta taaaaaggtg aagcacccat
    33061 acttcttgct gcatcttcca tctcatcatc aacactaaat aaaatagcac gtaccattct
    33121 ataagaaaat gggattttta caactatata tgcaataagt agaattacca aactacctac
    33181 caaaatctga ttcaagacaa gaaattgtgg ctgattaaaa gtaaataata aacttactgc
    33241 taaaagcgta cttggtaata accaaggaag tagagcacca tattcaaata agaaatcaaa
    33301 acgagattta tgttttctga caacacgagc aaatacaact gcgagaattg ttgctgttgt
    33361 cgcagcaata atagaataaa taaagctgac caagaatgga gagaatgccg cactattact
    33421 aaagaataag cgataatttt ctaaagtaaa gtttgataat gttaagttac ctgtttgaat
    33481 tgcaactgga tctgtaaatg agtataatac tataaaaatt agtggaagca tgaaaactgt
    33541 gaacaatcca tatgctacaa tgtgagcaat gatattccaa ggcttagacg caattttttg
    33601 ttttttaaga ggcgctttag tcttagagat agaaatataa tttccacctt tttctatctt
    33661 attcatgata gtaagcaaaa ttgtagttgc aatacctaaa ataattgcaa gtaaggcagc
    33721 taaatcacga gaattcccca tccctgcaaa tgtaataatc attggattta tagtttgaaa
    33781 ttctttacca ccaacaatca tgggtgctgc tactgcagat aaaccactaa gaaaaaccat
    33841 aatagtaagt gcaaatagag ttggaattaa ggttggtaac actacttttc ggaaaacagt
    33901 aaatggtttt gctcccatat ttcgagcagc ctcaatagtg tgatagtcaa cgcttcgaat
    33961 tgtatttgtt aaaaacaatg tatgattagc agttcctgaa aatgtcataa tgaataagac
    34021 tgcaccatac ccaataaacc agttagggtc taaagaaggg ataacatttt gtaaaaattt
    34081 tgtaatcaat ccatatggac catagacaaa tttatatcca gtcgctaaaa ccactcctcc
    34141 ataaattaaa gaggtcatat aacctaattt taaaatttta gcacctttaa tatcaaagta
    34201 ctctgtaaat agaacacaaa gaatacctac gacattaact gtaataatga gtgaaaatgc
    34261 taacttaaaa ctgttcataa tactctgaag tgccctctga gattttagaa cacgatgtac
    34321 agcatcaagg gaaaattctc ctccttttac aaatacattc actactagat caaagtttgg
    34381 ataaataata aatgttacta agaaccagat taaccctaaa cgaataagcc aatcttttaa
    34441 atttaattta tgacgcatac tgcacctcct taaaattgca gaacgtctga tggtgtgata
    34501 aataattcca cactttctcc gacagatcta atagcagcct gactatcaat acttgttaca
    34561 ttaagaatct gactttcaga aacttttatt gtatagtgaa ttgtaactcc agaaaactca
    34621 acatcaataa ttgtcccttt tagaatgaaa tcttgttcag tttcacgatt gaatcgaact
    34681 ttctctaatc gaatgtatcc ttttttatct tctaagaaaa cgcttgtatt tttcagtaat
    34741 acttcgtgga ctgtttcatc ggtcaaaaca ttaatatctc caataaaatc acatacaaat
    34801 tcagtttgag aattatgata aatctctact ggtgtaccga cctgttcgat gtatccattg
    34861 ttaaagactg caattctatc agataaagtc aaggcttcct cttgatcatg agtaacatat
    34921 aaagtagtaa tacctaactc tttttgaagt cttttcaact cttttctcaa atctacacgt
    34981 aattttgcgt caaggtttga caatggttca tctagacaaa gaattttagg ttcaagaacc
    35041 agagcacgag ccaatgctac cctttgttgt tgacccccag ataattctga tacattacgc
    35101 tgtaactgtt gatcagagat cttaattttt gctgccactg ctgatacttt agctttaata
    35161 acatctggag ctaccttctt aacttttaaa ccaaatgcaa tattatcaaa aacagtcata
    35221 gttggaaata gcgcataaga ttgaaataca ataccaattc cacgcttttc aggttccaaa
    35281 tgagtgacat ctgttccatt aacttcaata cttcctgatg atggatctaa aaaacctacc
    35341 aatgctctca aagtagttga tttaccacat cctgaaggcc caagaaatgt aaagaattcc
    35401 ccttcatgta tatctaaatt cagattatca attgcaacaa aatcaccata tttaatttga
    35461 atattatcaa atttaatcat ctcactaact ccctctatta ctaaaccaaa agcctctctt
    35521 tatttcttcc ttaaatttag aaataataga gagacttgga cataaaaaat aactcttatt
    35581 tcttatttta cgtattctaa ttcagctttt tctacccatt catccaaatg ctttccaaca
    35641 gcttcccagt caatattttg tggtttcact tgatcaacaa attttttcgt atcttcaggt
    35701 aactctttta gggcatcttt atttgcagga atagatccaa attttttact atattctact
    35761 tgaatttctg attgaccaaa ccaatcaata aattctttag ctaacgcttg ttttttacta
    35821 gtgcttaaaa ccatagtttg ttcagttaca aatggtacac caatctcagg agtcataact
    35881 ttgaattcaa cattttgttc tttttgtccg attaacgctc cagaacccca gatcataccg
    35941 tattgaattg ggctttcttt atctaacgct ttaacaactg agctttcacc tttttgaaga
    36001 gtataggcat ttgcaaagta ttcttttgca acttcccatc ctttttctga tacgcctaaa
    36061 tctccttttt catcaaggta acgaactaag atacttgcta gaattgcccg tcctgtacca
    36121 ccttgaagac cataaattga atatttacct ttatacttac tacctaattc agtccaatct
    36181 ttaggcattt cttttacatc aggcgcccca attaaaacta atggttgaac aatcacagga
    36241 ttataataat tatctttatc tgataaagat tgatcaattt tatctaacca tttaggcttg
    36301 tactgtacta gtaatttttg atctctaatt ttatttgagt caacagcacc aattccaaat
    36361 accatatctg caactgcatt attcttctca gcaataacac ggtctgctaa ttgagcgcca
    36421 gcaatatcaa ccatttttat attaaaacca gcttcttttg ctttagcagt taaccaatca
    36481 ccacgaccat ttgagactga gttcgaatag attactaatt cttgactttt atcagctttt
    36541 tcttcagatg aagaagcagt cgtagaattt gaacctccag agcaagcagc aagtgtagta
    36601 agagcaactc ccgttgcaag tacagtagac caaactttca tttttttcat gataagttct
    36661 ccttttttat tattttattt aaatttttcg tgatatggaa caaattgtct catatcttca
    36721 aatacagtat agtcaatacg gtttacagta atagttggaa tcttctctaa taaaatttca
    36781 gttaattctg ctctgacttt agtaaactct tcttcctcct cttcggttag aggaatccga
    36841 agatacccaa ttgaaatatg gaattgatat ctatcatgat tagggaaaca aacacctgct
    36901 ttttctgaga cataagtacg aatttcttct aatctctttg cagaagcttc atctgcaggt
    36961 tcaactagta tgttttgttt tcccatttca gttatacgca tatgaatttc ttcatccaac
    37021 aatggaaaaa tttcaagttg tttagcaaag taatcatgta tttcctgtaa aggtgtatct
    37081 agaggaagat tactgctcca aaactccgtt tcacgatttt catggcacaa caattcaatt
    37141 acagtcatgt gaatagaatt ccttggagtt aaagtaaact tatcgataaa tggtaattct
    37201 ctataacgtg attgaataat atcaacaact tccatcaaat cttgtttagt ataaagattt
    37261 gctacaactg tattcccagg gaaatgatta aattccccat tctctttgaa cttaattttt
    37321 gttaagtttt tcatataaag accttctttt ttatatttga catcggtgtc attgtgttta
    37381 cattatacaa tgaaaccgtt tcctttgtca agcgctgtca aacatttttt ttaatttatc
    37441 tttcattaaa ag
//
LOCUS       DAVBEM010000016        37259 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVBEM010000016 DAVBEM010000000
VERSION     DAVBEM010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37259
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.016"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            215..1978
                     /gene="aspS"
                     /locus_tag="VQ548_000834"
     CDS             215..1978
                     /gene="aspS"
                     /locus_tag="VQ548_000834"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HET2653712.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVVNATLGTLRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            1956..2897
                     /locus_tag="VQ548_000835"
     CDS             1956..2897
                     /locus_tag="VQ548_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET2653713.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(3017..3097)
                     /locus_tag="VQ548_000836"
                     /pseudo
     CDS             complement(3017..3097)
                     /locus_tag="VQ548_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(3233..4219)
                     /locus_tag="VQ548_000837"
     CDS             complement(3233..4219)
                     /locus_tag="VQ548_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2653714.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(4229..5029)
                     /locus_tag="VQ548_000838"
     CDS             complement(4229..5029)
                     /locus_tag="VQ548_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HET2653715.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRIYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(5290..6132)
                     /locus_tag="VQ548_000839"
     CDS             complement(5290..6132)
                     /locus_tag="VQ548_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2653716.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(6134..7426)
                     /locus_tag="VQ548_000840"
     CDS             complement(6134..7426)
                     /locus_tag="VQ548_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2653717.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGNKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(7537..8808)
                     /locus_tag="VQ548_000841"
     CDS             complement(7537..8808)
                     /locus_tag="VQ548_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2653718.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            9358..10875
                     /gene="malQ"
                     /locus_tag="VQ548_000842"
     CDS             9358..10875
                     /gene="malQ"
                     /locus_tag="VQ548_000842"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HET2653719.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            10901..13159
                     /locus_tag="VQ548_000843"
     CDS             10901..13159
                     /locus_tag="VQ548_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HET2653720.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(14203..14775)
                     /locus_tag="VQ548_000844"
     CDS             complement(14203..14775)
                     /locus_tag="VQ548_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653721.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAINLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(15397..16245)
                     /locus_tag="VQ548_000845"
     CDS             complement(15397..16245)
                     /locus_tag="VQ548_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET2653722.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            16390..16668
                     /locus_tag="VQ548_000846"
     CDS             16390..16668
                     /locus_tag="VQ548_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653723.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            16670..18733
                     /locus_tag="VQ548_000847"
     CDS             16670..18733
                     /locus_tag="VQ548_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET2653724.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(18811..20067)
                     /locus_tag="VQ548_000848"
     CDS             complement(18811..20067)
                     /locus_tag="VQ548_000848"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HET2653725.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            20209..22674
                     /locus_tag="VQ548_000849"
     CDS             20209..22674
                     /locus_tag="VQ548_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET2653726.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            22739..23650
                     /locus_tag="VQ548_000850"
     CDS             22739..23650
                     /locus_tag="VQ548_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET2653727.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCLEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            23880..24578
                     /gene="dapD"
                     /locus_tag="VQ548_000851"
     CDS             23880..24578
                     /gene="dapD"
                     /locus_tag="VQ548_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HET2653728.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVCVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            24646..25776
                     /locus_tag="VQ548_000852"
     CDS             24646..25776
                     /locus_tag="VQ548_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HET2653729.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFTSQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            25788..26327
                     /locus_tag="VQ548_000853"
     CDS             25788..26327
                     /locus_tag="VQ548_000853"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HET2653730.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLTPKTYPKGRMDFVVYDPQQLVKTSFALLEPQ
                     GDLEVVDASQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGRALSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            26311..26988
                     /locus_tag="VQ548_000854"
     CDS             26311..26988
                     /locus_tag="VQ548_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HET2653731.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(27060..27959)
                     /gene="galU"
                     /locus_tag="VQ548_000855"
     CDS             complement(27060..27959)
                     /gene="galU"
                     /locus_tag="VQ548_000855"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HET2653732.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(27981..28997)
                     /locus_tag="VQ548_000856"
     CDS             complement(27981..28997)
                     /locus_tag="VQ548_000856"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HET2653733.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     YHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKAI
                     IMHASKGLEPDSHKRLSTILEEEIPEQLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            29209..29586
                     /locus_tag="VQ548_000857"
                     /pseudo
     CDS             29209..29586
                     /locus_tag="VQ548_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(29766..30191)
                     /locus_tag="VQ548_000858"
     CDS             complement(29766..30191)
                     /locus_tag="VQ548_000858"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2653734.1"
                     /translation="MNNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKSLTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(30259..30909)
                     /gene="phoU"
                     /locus_tag="VQ548_000859"
     CDS             complement(30259..30909)
                     /gene="phoU"
                     /locus_tag="VQ548_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET2653735.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(30924..31676)
                     /gene="pstB"
                     /locus_tag="VQ548_000860"
     CDS             complement(30924..31676)
                     /gene="pstB"
                     /locus_tag="VQ548_000860"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2653736.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(31678..32493)
                     /gene="pstA"
                     /locus_tag="VQ548_000861"
     CDS             complement(31678..32493)
                     /gene="pstA"
                     /locus_tag="VQ548_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET2653737.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(32486..33349)
                     /gene="pstC"
                     /locus_tag="VQ548_000862"
     CDS             complement(32486..33349)
                     /gene="pstC"
                     /locus_tag="VQ548_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET2653738.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(33467..34342)
                     /locus_tag="VQ548_000863"
     CDS             complement(33467..34342)
                     /locus_tag="VQ548_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HET2653739.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(34509..35840)
                     /locus_tag="VQ548_000864"
     CDS             complement(34509..35840)
                     /locus_tag="VQ548_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HET2653740.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSALKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(35841..36548)
                     /locus_tag="VQ548_000865"
     CDS             complement(35841..36548)
                     /locus_tag="VQ548_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2653741.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(36632..37117)
                     /locus_tag="VQ548_000866"
     CDS             complement(36632..37117)
                     /locus_tag="VQ548_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HET2653742.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            37103..37259
                     /locus_tag="VQ548_000867"
                     /pseudo
     CDS             37103..37259
                     /locus_tag="VQ548_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT        10924 a         7064 c         8036 g        11235 t
ORIGIN      
        1 ggttttgagg ttgtagatga aactgacgaa gtcagtaaca atacctacgg taaggcgacg
       61 ctgacgtggt ttgaagagat tttcgaagag tattagcgct aatttttagg gctttcacct
      121 gacttttaaa gactggcaaa cttttctgat gattttcatg aagagcctgc gcttttatgg
      181 taaaatagta acagaataaa agaggagaga aataatgaaa cgtagtatgt atgctggtcg
      241 tgttcgtgag gaacacatcg gacaagaaat aaccttgaaa ggatgggttg gccgtcgtcg
      301 tgaccttggt ggtttgatct ttatcgatct tcgtgaccgt gaaggaatca tgcagttggt
      361 tatcaaccct gaaaaagtat ctgcagaggt tatggcaaca gctgaaagcc ttcgtagcga
      421 atttgttatt gaggtgactg gtcaggtcgc tgcgcgtgag caagccaatg ataagttgcc
      481 aactggtgcg gttgagttaa acgtgacagc tcttattgtg cttaacacag ctaagacaac
      541 accatttgag attaaggatg gcattgaggc aaatgacgat acacgtttgc gttaccgtta
      601 ccttgacctt cgtcgtccag aaatgttgga aaatcttaaa cttcgtgcca aggtgaccca
      661 ctctatccgc aactatttgg atgagttgga gtttatcgac gtggagacac cattcctttc
      721 taagtcaacg cctgaagggg cgcgtgatta tttagtgccg tctcgtgtta ataaggggca
      781 tttttacgct cttcctcaaa gtccacaaat cacgaaacag ctcttgatga atgctggttt
      841 tgaccgttac taccaaatcg ttaaatgttt ccgtgacgag gacttgcgtg gagaccgcca
      901 gcctgaattt actcaggtcg acttggaaac gtccttcctt actgagaaag aaatccaaga
      961 tattacagaa ggcttgatcg cgcgcgtgat gaaggaaaca aaaggcatcg aagtaacgct
     1021 accgttccct cgtatgaaat acgatgatgc tatggctctt tacggttctg acaagccaga
     1081 tactcgtttt gacatgttgc ttcaggactt gacagaagtg gtcaaaggtg tagactttaa
     1141 agtcttttca gaagcacctg ctgtaaaagc gattgtggtc aaaggagctg cggacaacta
     1201 ttcacgtaaa gacatcgaca agatgacgga agtagccaaa cagtatggtg ccaaaggtct
     1261 tgcttgggtc aaggtggttg atggagaatt aaacggacca gttgccaagt tcttgactgg
     1321 tatccaagaa gaattgacaa cagcgcttgc tcttgaagat aaggacttgg ttctctttgt
     1381 ggcggatacg cttgaagtgg ttaatgcaac actgggtacc cttcgtggac gtattgctaa
     1441 agagcttggc ttgattgata atgataagtt caacttcctt tgggtggttg actggccgat
     1501 gtttgaatgg tctgaagaag aaggccgcta catgagcgcc caccatccat tcacacttcc
     1561 acaggaagag actgctcacg aattagaagg tgatttggct aaggttcgtg ccattgctta
     1621 cgatatcgtc ttgaacggtt atgagcttgg tggtggtagc cttcgtatca accaaaaaga
     1681 ccttcaagaa cgcatgttca aggctcttgg tttctcaact gaagaagcca atgaccagtt
     1741 tggtttcctt cttgaagcca tggactatgg tttcccaccg cacggtggtt tggctatcgg
     1801 gcttgaccgt tttgtcatgt tgcttgctgg agaagaaaat atccgtgaag tcattgcctt
     1861 tcctaagaac aacaaggcaa ctgacccaat gacacaagct ccatcaacag tcgctctcaa
     1921 acaactagag gaactcagct tacaagtaga agaagatgaa acaaacaaaa cgaattaagc
     1981 ggtggcgcta ttatctgcgc cgctttgctt atcagataaa aattttacgt gtcttacaaa
     2041 gtatctctcg agaaaagtat gatgagaaga tttcggcctc tctggtctat ggttttttat
     2101 cagcagtagc agttaatttc tttttccaac cagggcatgt gtattcgagt ggtgcaacag
     2161 gtctggcaca gattatctct gccttgagta atcactggtt tggttttcat attccgattt
     2221 cgctaagctt ctacgccatt aacttccctt tgatggtctt agcttggtat cagattggcc
     2281 ataagttcac cgtctttacc tttatcacgg tatctatgag ttccttcttt atccagtttg
     2341 tccctgtggc aaccttgacg gaggatccca ttatcaattc cctttttggg ggtgttgtta
     2401 tgggtttggg gattggtttt gctcttcgaa acaatatctc cagtggtggg acggatatcg
     2461 tcagcctgac tattcgtaag aaaacgggta agaatgtcgg tagtatttct ttcttggtaa
     2521 atggaactat catgctgata gcaggtttga cctttggttg gaaatacgct ctttattcta
     2581 tgattaccat ctttgtctct agccgtgtga cagacgcagt ctttactaag caaaagcgta
     2641 tgcaggccat gattgtgaca aatcatccag agaaggtaat tgaaaaaatc cataaaaaat
     2701 tgcaccgcgg agcaaccatg atccacgatg cagaaggaac ctataatcac gagagaaagg
     2761 cagttttaat cactgtcatt acacgtgcag agtttaatga atttaaacag attatgacac
     2821 aagtggatcc aagctccttt gtctctgtct cggaaaatgt tcatattcta ggaagatttg
     2881 ttgagataga taattagtga ttaatactct tcgaaaatct cttcaaacca cgtcagcttc
     2941 accttgccgt atatatgtta ctgacttcgt cagttctatc tgcaacctca aaaccatgtt
     3001 ttgagctgac ttcgtcagtt tcatctacaa cctcaaaacc atgttttgag caacctgcgg
     3061 ctagcttcct agtttgcact ttgattttca ttgagtataa aaagatcttg ggaaaagact
     3121 caatttcagt agaaaaggaa gtaaatcttc ccacattaaa acgcatagta tcaagttttt
     3181 tcaatacctg atagtatgcg tttttgcttt taacgacttt ttgcccagtc tcttattttt
     3241 cgataatttt gtgggcgatc aattgacggt aacaaatttg tttattgttt ttattatcat
     3301 taataatctg gagaatagtt tcaagggaaa cacgaccaag ctctaaacta ttgatatcga
     3361 cataggctgc caagttgagc ttgggattaa ccgagtcaaa gctgagaaca gggacatcca
     3421 gctggtgttt ggcaatatag ttacaaacgc cttcagctag gaggctatcg gttgtgatga
     3481 tagcatcaat ttgtggatcg tgcttgaata atcgcttgct aaatttatag cccttttctt
     3541 ccagaaactc gtcggcaaag tagatgcgat tgttgtcagt ggtaagtttg taatgtttaa
     3601 gcgcctgttc atagcctgtt aaacggtctt tggtcacgaa gagcttttta cttcctccga
     3661 taaaggcaat gcgtttgcag ccttttttga tgaaatattc agtcgcatca aaaccagctt
     3721 gaacattgtc gttgtcgaca agtgggatga aaggagatag agatttacct aagataagga
     3781 aggggaactg ttcttctgcg acgagtttta cgagagggtc ttcttcttgg gcatagagaa
     3841 agattagccc atctacacgc ttgccgtaga ccatttgtga aatagcgttg agacgctcct
     3901 tctcatcttt ccctgttgct atctgaatgg catagtggtt ttcagatgcg acttgagaga
     3961 tgccacgtag aaccgatgga aagaaaggat tctggtagaa ggcgtctgag tcatcaggaa
     4021 gaactaatcc gataacctga gtatagctgc ttaccaagct acgagcgttg aggtttgggt
     4081 ggtagttgag ttccttcata gctttgcgaa cgcgtttttt tgtttcgtcg ctaatggttg
     4141 atttattttg aataacacgg gttacggttg aaggcgaaac accagcagcc ttggccacgt
     4201 ctttaatcgt aacgggcata aaaatctcct atttatggta atttggatca cggaaatgtg
     4261 ttttataaaa gatagtgacc agatacagaa caaaaagaat attttgtaca gtaatcaggg
     4321 ttgtcatatt ttggccaaat aatcccaaaa taagtgtaat cagagtcggc aatcctaaac
     4381 agttcaagat aaagtgatag cactctttaa aggttctaaa tgaaaagagg cgtgatttct
     4441 tagtgatata aaggagaaga ctagctccta gagagacgat aaagaaattc aaaccaaaga
     4501 ggaagctcgc accgagaact aggaagaggc tgatatagat acgattttgt tggtaccagt
     4561 ctttagaaat tgcttgggtc aagctgtctt tgcttttgaa actctcagtc tgaatggctc
     4621 ggtaagagat gcgggtcagt tccttgcttt ccttgctgat gactagttca tttgtatcga
     4681 aatgcagttg caagtcctta ggtaattcct tgatttgact tggaccaatc acaacagaag
     4741 gggcttgact agctgttcca gtataagtta atgtgccatc gacaattgta gcatgttcag
     4801 agagatcctg gacaacctca tttgtcagag gttcatagac attatcgata aaagtttcta
     4861 gcggataggt ctcctgggag ctgttttgga tagcaatggg taccatagac aagctgataa
     4921 ggaagatact ggtaaagaga agttgaaacc agttgagctc gaaacgtttg gacaggggct
     4981 tacgaaaccc ccaaatactt gaaaaatagg aaaatggata tggaagcata ggtatctttc
     5041 taaaaggtgt tttctatatg agtattatta tatagagaaa tgcgctttat ttcaagtcta
     5101 ggagaaaaat tgcttgctac aaggatatta tttacagtga caattgctaa taatcaatga
     5161 aaatcaaagt gcaaaccagg aagctagctg caggttgctc aaagcacaac tttgaggttg
     5221 gagataaagc tgacgtggtt tgaagagatt ttcgaagagt ataaaatgaa aaagggtggc
     5281 ggggataaat tatcccttgt cgccaccact tgtaagtcct gaaacaaagt tcttttgtag
     5341 aaagaagaag agaatacaga ttggaagggc gatgaggata gcacctgctg agaagtaggc
     5401 aatcttcaag tttttcgcat tgttaacgaa ggtttggaga cctacggcaa cagtaaagta
     5461 ttctttctca cgaagcaaga aactagagag gatgtagtcc ccgaaaggtc ccatgaaggc
     5521 ccagagagct tgtacggcaa ccattgggcg aacaagtggt agaacaattt gccagaagcg
     5581 gcggaagtgt cctgcaccgt ctagttttgc agattcgtct aaagacattg gcactgtatc
     5641 gaagtagcct ttcatgagcc aagcattcat cgggatacca ccaccaacgt agaggaagat
     5701 gaggaaccag ttgtggttaa gggcgttcaa cataagcgcc ataacgaaga aggctgtcaa
     5761 agcggccata gttggcacca tttggatgat caagaagaag accaaacttt gtttacgagc
     5821 caagaagttg taacggctgt aagcataacc agcaagtacg atgatacttg tttgaacagc
     5881 catggtaatt aaggcgataa tcaaagtgtt gaggtaccaa gtaccgtaca aggtttcagt
     5941 gaagaggcct ttaaagttat caaaattgag gtcgatatta gtatctagtt taaaggctga
     6001 gacgttacct gctttaaagg ctgacataat ggtaatcaac agtggataga taattacaat
     6061 tgatagacca atcaggtaaa ggtaagtaag gctttgagtc agtctacgtt tgagtttaat
     6121 tgagttattc atcttagacg tcctccatat caaatgcgtg tagtttcttg aatgcgatca
     6181 tagagattga gatgacaatg atagagataa tcaaggtaac agctgccgcc attgagtatt
     6241 gaggagatgt acctgttgtc aaacggtaga tccatgagat caagatatcg gttgaaccag
     6301 ctccacctcc gacactacca ggtcctccac cattgaagag gtacatgata gagaagttgt
     6361 taaagttgaa ggtgtattgg ctaatcaaag taggtgccgc aacagccaaa atcattggga
     6421 aagtgatgtt gcggaatttt tgccaagcgt tggcaccgtc aatataagct gcttcgtaaa
     6481 ggtcgttagg aatagattgc aagataccca aagtcaaaac gtagatgtat gggaatccga
     6541 gccaaccttg catcataatc aaggcaatct tagtccaagt tgggtctgtt ttccaaggaa
     6601 taagagctcc atcaaggaaa ggaaggaatt tagccaagat tggcaatact tgagtgttga
     6661 tagcaccgac actatcgtta aacatgtttg agaatgtcaa gatagtgatg aaggctggga
     6721 cagcccaagg aagaaggaaa ataacaccaa agatacgttt tcctttgata aatggttggt
     6781 tggcaatgat agctgtgaag ataccaatta cgatttgtaa agtagaagct gccaaagccc
     6841 aaatgatagt ccaagaaaga acagaaccaa aggcagaacg gaaggtactc aagctccaaa
     6901 tgtttgtaaa gttggtcaaa ccaacccagt ccaacaactt gtttggtggc aagtgttgga
     6961 agtcgtagtt ggtaaaggcg atcatcaagg ttacgataac tgggaagata atcgcgaagg
     7021 tcatggcaac ataagatgga atgatcaaga ggtaagggaa gccattttca taaatccctt
     7081 tgatcatgtc tttgagtgtg cgtggaactg gaattccatt gttaatgcgt tttgcaatcg
     7141 tatgtgcatc tttgatattt gagaaataaa agagtacata aacgattaca aagattagat
     7201 ggaaggcacc acgaatcagc ataaagaggg aattatcacg acctggtttg ttaccaagag
     7261 tgatgaggtt gctcaattca ggggttgcaa gtgctaggaa gtaaaggaca aatacgatgg
     7321 ttacaccaag gaagataaaa cctttggctt tttgtttatt gtaaatctgt cctaacccag
     7381 gaatgataga cagcagggct gctttactag gttgttgctt ttccatatta actcctttca
     7441 taggatacta cttttttata agaaagctaa attatttgtg tctctattga taaattcaaa
     7501 gggggatttg atttccaccc cccttgaaca aattttttat tcaccaaatt tttgtttgat
     7561 tgtttctttg atcaatgtta cagcatcgtt agcagctgtt ttagcatctt tttgaccact
     7621 tacagcatca aagagcatat ttttcgctgg atcccaaact gcagacattt gagagatgtt
     7681 tggcagtggt tgagtgttct tgaactgttt gataacagct gttgtcaact catcgttttt
     7741 accttcagcg tatgaacgag cctcagtatt agctgggatt tcgttagtct tatcatataa
     7801 tactttttgt tgttcagttg caacaaggaa gtctacaaat ttttgagaag cttcaaggtt
     7861 cttaacggct tgaggaatga cccaagcttt accaccaccg aatgcagcat attcttttcc
     7921 atttggaaga gttgggatag ttgcaactcc gtagtttact ttagcatctt taaaggcttg
     7981 agctttccaa ggtccgtcga tgatagcagc tgttttacct tcttggaatt gagtttggat
     8041 taagtttcca gcaccttctg tatcttgcat acctttaggc catttttcgt accaagattt
     8101 agcgtaattg atacctacga tagaaccgtc gtttgcaaga ccgatgtctt tagcgtcttt
     8161 accgttttgg ccaaagacgt aagcaccgtt accggcaaga agtccatatg tatagtagaa
     8221 gtttgtccag tcagctagga aggcagtagt tttaccatct tcaccagcga atgcgtattt
     8281 gctatcttta gcaaggtttt ccaagtcagc aaatgttttt ggagcatctt tcaccaagtc
     8341 tttgttgtag tacataacaa gtgactcgat aacggcagga gcaccgtaaa ctttaccatt
     8401 agcagctgtt acaagagatt tagttgtgtc gtctgtttta gcaccatcgc tcaatttcac
     8461 ttctgaaagt tgtccgtcag aaccaaggct acctacacgg tcgtatggag ccatcataac
     8521 atcagggaca ttaccagatt ggttgtcaag agaaagttta tcaagacctc ctagagcatc
     8581 accagtttta agagtgactt ttactccagc ttctttttca taagctttag caacctcttc
     8641 aatatagctc ttatatccct cgtctacata tacagtgagt tctttgactt cagatgaacc
     8701 agaatcagca ggcttatcag cagttttgct tccgcaagct accaaaagca agctagcaag
     8761 tgtagcagtt ccaagcaccg cagtgctctt cataaattta gatgacatag tgtattcctc
     8821 ctaaagaata gcaagtttta ttgataagga aacgcaaacg ttttccttta tgagcttagt
     8881 atagcacaaa tagaaaacgg ttgcaagtat tttttgtaaa aattttaaaa aatttttaag
     8941 cttgatttga tagcataatt ttgcatttta atagaagaaa agtatgaaat agataagaat
     9001 acagtatttt taataaaaat atatggaatc tgtctaaaga gggaaatcag gaggggctac
     9061 ctccctgttt ctaatctata tctattttct atagacgttt gtgctttgtt acatataaat
     9121 tcaagctccc taaggaggtt ttatactttg tagactgtct cgtgagagtc aaaccttagg
     9181 attagatagt tttaagttat ctttgctaaa atgagttagt ttccttaaaa ataatcaaaa
     9241 aagtttttta aaaacgcttg caattatgct tgaaaaggag tatacttata agtaacgcaa
     9301 acgtttgcgt ctgcaaaata cgcaacgttc cattatttta acacacgagg tgctattatg
     9361 aaaaaacgtc aaagtggtgt gttgatgcac atctcttctc ttccaggagc ttacggaatc
     9421 ggatcatttg gtcaaagtgc ttacgacttc gttgatttct tggtccgtac aaaacaacgt
     9481 tactggcaaa tccttccatt aggagcaact agttacgggg attctcctta ccaatctttc
     9541 tcagccttcg caggaaacac tcattttatc gatttagata tcttggtgga gcaaggtttg
     9601 ttggaagcaa gtgaccttga aggagttgac tttggtagcg atgcgtctga agttgactat
     9661 gctaaaatct actatgcacg tcgtcctctt ttagaaaaag cggtgaaacg tttctttgaa
     9721 gtcggagatg ttaaagattt tgagaaattt gctcaagaca accaatcatg gcttgagctc
     9781 tttgctgagt atatggctat caaagagtat tttgacaatc ttgcttggac tgaatggcca
     9841 gatgcagatg ctcgtgctcg taaagcttca gcacttgaaa gctatcgtga gcaattggca
     9901 gacaagttgg tttaccaccg tgtgactcaa tacttcttct tccaacaatg gttgaaattg
     9961 aaagcttacg ctaacgacaa ccacatcgaa atcgttgggg acatgccaat ctacgtagcg
    10021 gaagattcaa gtgatatgtg ggcaaatcca catctcttca aaacagatgt caatggtaag
    10081 gctacttgta tcgcaggatg cccaccagat gagttttctg taactggtca gctttggggt
    10141 aacccaatct atgactggga agcaatggac aaagacggct acaaatggtg gattgaacgc
    10201 ttgcgtgaaa gcttcaaaat ctacgatatc gttcgtatcg accacttccg tggcttcgaa
    10261 tcttactggg aaatccctgc tggttccgat acagcagcac ctggtgagtg ggtgaaaggt
    10321 ccaggctaca agctttttgc agccgttaag gaagaacttg gtgagctaaa catcatcgca
    10381 gaagaccttg gcttcatgac agatgaagtg atcgaattgc gtgaacgtac tggcttccca
    10441 ggaatgaaga ttcttcaatt tgccttcaac ccagaagacg aaagcattga tagcccacac
    10501 ttggcacctg ctaactcagt tatgtacaca ggaacacacg ataacaatac ggttcttggt
    10561 tggtaccgta atgagattga tgatgcgact cgtgagtaca tggctcgtta cacgaaccgt
    10621 aaagaatacg aaacagtggt acacgctatg cttcgtacag tattttcatc agttagcttt
    10681 atggcaattg caactatgca agatttacta gaattggatg aggcagctcg tatgaacttc
    10741 ccatctaccc ttggtggaaa ctggtcttgg cgtatgactg aagatcaatt gacaccagct
    10801 gtcgaggaag gtttgcttga cttgacaaca atttatcgcc gaattaatga aaatttggta
    10861 gatttaaaga aataagacaa taatcaggag acaactaaac atgttatcac tacaagaatt
    10921 tgtacaaaat cgttacaata aaaccattgc agaatgtagc aatgaagagc tttaccttgc
    10981 tcttcttaac tacagcaagc ttgcaagcag ccaaaaacca gtcaacactg gtaagaaaaa
    11041 agtttactac atctcagctg agttcttgat tggtaaactc ttgtcaaaca acttgattaa
    11101 ccttggtctt tacgacgatg ttaaaaaaga acttgcagct gcaggtaaag acttgatcga
    11161 agttgaagaa gttgaattgg aaccatctct tggtaatggt ggtttgggac gtttggctgc
    11221 ctgctttatc gactcaattg ctactcttgg tttgaatggt gacggtgttg gtcttaacta
    11281 ccactttggt cttttccaac aagttcttaa aaacaaccaa caagaaacaa ttccaaatgc
    11341 atggttgaca gagcaaaact ggttggttcg ctcaagccgt agctaccaag taccatttgc
    11401 agactttact ttgacatcaa ctctttacga tattgatgtt actggttatg aaacagcgac
    11461 taaaaaccgc ttgcgtttgt ttgacttgga ttcagttgat tcttctatta ttaaagatgg
    11521 tatcaacttt gacaagacag atatcgctcg caacttaact ctcttccttt acccagatga
    11581 tagtgaccgt caaggtgaat tgctccgtat cttccaacaa tacttcatgg tttcaaacgg
    11641 tgcgcaattg atcatcgacg aagcaatcga aaaaggaagc aacttgcatg accttgctga
    11701 ctacgcagtt gtccaaatca acgatactca cccatcaatg gtgattcctg aattgattcg
    11761 tcttttgact gcacgtggta tcgatcttga cgaagcaatc tcaattgttc gtagcatgac
    11821 tgcctacact aaccacacaa tccttgctga agcgcttgaa aaatggcctc ttgaattctt
    11881 gcaagaagtg gttcctcact tggtaccaat catcgaagaa ttggaccgtc gtgtgaaggc
    11941 agagtacaaa gatccagctg ttcaaatcat cgatgagagc ggacgtgttc acatggctca
    12001 catggatatc cactacggat acagtgttaa cggggttgca gcactccata ctgaaatctt
    12061 gaaaaattct gagttgaaag ccttctacga cctttaccca gaaaagttca acaacaaaac
    12121 aaacggtatc actttccgtc gttggcttat gcatgctaac ccaagattgt ctcactactt
    12181 ggatgagatt cttggagatg gttggcacca tgaagcagat gagcttgaaa aactgttgtc
    12241 ttatgaagac aaagcagctg tcaaagaaaa attggaaagc atcaaggctc acaacaaacg
    12301 taaattggct cgtcacttga aagaacacca aggtgtggaa atcaatccaa attctatctt
    12361 tgatatccaa atcaaacgtc ttcacgagta caaacgccaa caaatgaacg ctttgtacgt
    12421 gatccacaaa taccttgaca tcaaagctgg taacatccct gctcgtccaa tcacaatctt
    12481 ctttggtggt aaagcagctc cagcctacac aatcgctcaa gatatcattc acttgatcct
    12541 ttgcatgtca gaagttattg ctaacgatcc agcagtagct ccacacttgc aagtagttat
    12601 ggttgaaaac tacaacgtta ctgcagcaag cttccttatc ccagcatgtg atatctcaga
    12661 acaaatctca cttgcttcta aagaagcttc aggtactggt aacatgaaat tcatgttgaa
    12721 cggagctttg acacttggta ctatggacgg tgctaacgtg gaaatcgctg agttggttgg
    12781 agaagaaaac atctacatct tcggtgaaga ttcagaaact gttatcgacc tttacgcaaa
    12841 agcagcttac aaatcaagcg aattctacgc tcgtgaagct atcaaaccat tggttgactt
    12901 catcgttagt gatgcagttc ttgcagctgg aaacaaagag cgcttggaac gtctttacaa
    12961 tgaattgatc aacaaagact ggttcatgac tcttcttgac ttggaagact acatcaaagt
    13021 caaagagcaa atgcttgctg actacgaaga ccgtgacgca tggttggata aagtcatcgt
    13081 taacatttct aaagcaggat tcttctcatc tgaccgtaca atcgctcagt ataacgaaga
    13141 catctggcac ttgaactaat actcttcgaa aatctcttca aaccacgtca gctttatctg
    13201 caacctcaaa gcggtgcttt gagcaacctg cggttagctt cctagtttac tctttgattt
    13261 tcattgagta taagatacaa atttatacta atacatcttg taaaaaagcg agtttcgatt
    13321 gaaattcgct tttttaatga tgtagatttg ggtcaatctt gtctaaaaat agggaaatcc
    13381 tagatacagt gaaggcttta aatgctggtt tttactgtcc tcagccttat attttttcgt
    13441 agttgattac ctcatacctc ttgtattcgc ttacataaag tattataata taattgtagg
    13501 aaagaaggtg tttttatgat atacacactt aaattggtgt tgtttattac ctttcttgta
    13561 ataagcttgt tacctgataa gatttttgga aaaaataaaa aaatttggaa aatagttttt
    13621 gcaatattga cggcagtggc agcattgtca tttatgtact aagttatttt aagaatgtag
    13681 ggaaataaac cctacattct ttttagtttt ttctgttttc taaattctat ttatccaagc
    13741 gcttcaacat ttcttgcttc ttcgcttcaa gttctgcacg cttttcttcg atttcggcat
    13801 gttttttctc gagttcagaa caacttgcac cattgctaaa ttcttttcgc catcaggaga
    13861 tagggtgagt cgacatgtct attactcacc caaagcagtc ctacaaagca ggaattttct
    13921 gttacttttt tggaaatagt aacgtttata cagctttgac acttcgtatc aaagcgccaa
    13981 acacactccg agggatttac agaaagcaga aaaggaatga tctggtataa gatcattcct
    14041 tttctctctt tttctttaag taattatata caatgtacga cgaagtcgtc attgcaatgc
    14101 tgatccacca cctaaaggaa actttaaaca acattgataa gataaagaat ataaacaacg
    14161 aaaatacgtt atacccaatt aattttattg tatatctcat gattaaaagt taatccttcc
    14221 gttgttagga atggcatcat ttttatccca taattgtgct aaataagtcc ccggtgataa
    14281 taaatttata gcaaattcta aagcaacatc atttacaaac caactaccta gatatctaga
    14341 aattgctgaa cgaatagcac tttttgctgc atgttttcct tttactttaa ttagatttgc
    14401 aaggcctgca gtagttcctc ctaatgctaa agctattgca gtatctaata gagcacccat
    14461 ttgattaact gtaatacctt gccaagctgc tctaaatgga gagtatgtag gtgggattgt
    14521 ataatcgcct tgtaattgtc ggttaattac ttctttgatc cattgttgtg agacgtctgg
    14581 atgaaaagat tggatttcgt ttgcaagtgt attgatttgt tcttctgtta gagaagtgac
    14641 aggttgaagt tccatatttg tttcaatttg tgatacttgt tcagaagcgt atacagctga
    14701 aacacttgga atcgctgata caattaacac aattgacgtc aaaaaaaccg aaataaattt
    14761 cattaatttg ttcatgagct tttctccttt ttatttgtat ctgcttacat tttatcatat
    14821 gctgttatta tagtcaaaaa aatatgctat tatgttaaaa aaatattttt caaaatataa
    14881 atggacggat ttattttgga ttttatttgt tattttgacc tgcctctata ttggtaacca
    14941 tgatttgttt actctcaatc atcaagaatt ctcttttcgt ggtagcgttt ggggtctggt
    15001 actggcctta tatcacttac tattcattga taagtttgtt atatcgaatc gaaaataaag
    15061 attagagcta tgcttgactg tgtactttta ggattgattt tggaggaaga ttttgtctct
    15121 attatttatt attttaaatt tatttatttt gtataagatc tattctttga ggcgggaaaa
    15181 atcgaaatac ttgatttata cggcctatat catatttggg gtaaatgtag tatatggtat
    15241 tcaatggtta ttaagagaac tgatttcaac tatttcccct taatgtgtat ggaaactata
    15301 acaaaacgca taagattaag gtttgtgtac ctgttcttat gcgtttttat aatattgaag
    15361 attttcggta agttttatac ctttgggaag tctagtttag aatgctttcc caaccaaaat
    15421 ctctgcttcg atggtaatct ctgtcagttg gctccagtca atcttgctct ggtcaacgtg
    15481 aaagaggaga ggagtcatac tgagtagggc ttggagttgt tctgctgtga tagtcttagt
    15541 cagagaggca gtttgactag ataggatggt aaagtgttcc tggaaatgct ccttgatatc
    15601 ttggttagaa tactccttgt ttgtcagctg gtcctgtact ctttgacgga tttctttgag
    15661 gtgattttca gttgggataa cctttatcaa gataccgtct ttggataaaa cgcgacgaaa
    15721 ttctccatag ttggcaggtg agaagatatc aagcagaata tccatgttag cgtcttttat
    15781 aggaagtcgt gccaagtcgc caacgaacca attgactgcc cagttgggtt cacttttagc
    15841 agcgatttgg actgaatctt tggagatgtc aaaggcatag aaagtttttt cagagtgact
    15901 ttcttgtagt ttgcgagaat agaatccttc accacaaccg atatccaaaa ttgttgtggt
    15961 agtttttgag cttgcaagca agtcagatac agcatctaag atagcttggt aaaagccggc
    16021 ttctaggatt tgttgacggt tttgaaaatt ttccttgtca tagttagcag attgcttgat
    16081 ttgaggtgct agattgacat agccaaattt cgccaagtca aaagaatgac ggttgcagca
    16141 cttgaaatta gtctctaaca gagtcagatt ttcttgacag ataggacagg caaaggcagt
    16201 cgcagaagca aaacgctgaa gtttgggctt gagatttgta ttcatagttt aagtgtatca
    16261 aaagaggcaa atgaaagcaa ctttaggaat aagtagattc agtagaaata aaactaattc
    16321 tccaatttat agaatgaaat tgcttttata tctaaattgc tatataataa tgataaggag
    16381 gaaataagta tgttaaaaga agtattaacc gttgcaaaag ttgcgaaaaa atcttcatta
    16441 tttttgggtg gtgtcgcatt tggtaccctt ggtttgaaaa tcttagcaag taaggaagct
    16501 aaaaaaggtt attctaaagc tttggctaag gcttacaagt tgaaagacga gctagatgca
    16561 tctgtttctg ttgtgaagca acatggagac gatgtcttgc aagatgccaa atatttgtac
    16621 gagcaagaga aaaaagaaga gcaattagat agccttatag gtgaataata tgtcttttaa
    16681 agtgctacat agaggatacc aacatatccg actatcatct tctttttcac ttaccttgga
    16741 tattcaagac tatcttcgtt ccttggcgag agatgaaaag gggattgagt ctatccagtt
    16801 ttacatggat caacagcact ttactctacg cataaaagaa ggcttttctg tattagataa
    16861 tgcagaagcc tttttaaaaa gaattgataa agggaaagtt tctgagttga tgactcttcc
    16921 cattcgtaga gaagagagtg cttattctat tgtttcaggt gcagcggtta agcgtgtact
    16981 ttttcgtagt tttgtgccgt atcctattcg ctatatatgg acttgttatc aggctttggg
    17041 ttatattaga gaagcctatc aaacactagc gcgtaaggaa ctaacgatgg aagtcttgga
    17101 ctgttcggct attttattgt ccttgtttat gaaccaatcc aagacagcta gcaatatcat
    17161 gtttatgctt gatttgggga atcatttaga tcagtggtcc ttgaaaaaaa ctgcaacaga
    17221 tttagaacag agtcttcttg caaaagagag cgatgtattc ctagtacagg gcgatacggt
    17281 tgttagtatc aagagttccg atgttcaaat aggagatgtc ttgatcttat ctcaaggaaa
    17341 tgaaattctg tttgatggac aagtagtttc aggtttaggt atggtcaacg aaagttcctt
    17401 gacaggagag agttttccag ttgaaaaaag agagtctgat ttggtttgtg caaatacagt
    17461 attagaaact ggagagttac gcattcgtgt aacagataat cagatgaaca gccgtatttt
    17521 acagctgatt gagttgatga agaaatctga agaaaacaag aaaacgaaac aacgctattt
    17581 catcaagatg gcggataaag tcgtcaaata taatttcttg ggggctgggc tgacttacct
    17641 attgacaggt tctttttcta aggctatttc tttcctattg gtcgatttct cctgcgcttt
    17701 gaaaatctct actcctgtag cttatttgac agttatcaag gaagggttga accgtgaaat
    17761 ggtgattaag gatggagatg ttctggagaa atatctggaa gttgatactt tcttgtttga
    17821 taagacagga acaatcacaa ctagttatcc tatagttgaa aaggtgttac cttttggaga
    17881 ctatagtgag gaagatattc tcagaatcag tgcctgtctt gaggaacaca tttatcatcc
    17941 tattgctaat gccatcgtca agcaagctga gatagaggga attgaacatg aggaaatgca
    18001 tgggaaactc caatatatcg caagcaaggg gatcaaatct catatagatg gccaaccagt
    18061 tcttattggg aattatgtct tgatgcagga tgagcagatt catatcagtt cagaacaaaa
    18121 tgctttaatt gaagagtaca agagtcacta caatctctta ttcttggctt atcaaaatga
    18181 attgattgga atgttctgca ttcatactcc tttgagaaaa gaagcaaaaa cagccttgga
    18241 taaacttaag gcacagggga aaaaattgat tctggcaaca ggagacacct tgattaggac
    18301 agaggaatta gtcaaagatt tgccctttga tcaggtctat acagacttga aacctgatgg
    18361 gaaatttgag ttagtagaga aactgcagaa agcaggtcac actattttga tggttggaga
    18421 tggattgaat gactcagcgg ctttaactct atcagatatc ggtgtggtga tgaatgagag
    18481 tgcagatatt tctaagcaga tgagtgatat cttattgtta gataatcgtt tggatttctt
    18541 ccaagagttg gattcgttat catcatcttt gcaaacactc atcaagaaaa atattcagga
    18601 taccgttgtc gtaaatagta gtttgattgg ctttggctta tttaattggt tcagtccttc
    18661 aaatctctct atcttacata atctaacaac cttgcgcatt gtcctgcgta gcctgtctat
    18721 taaaaataga tagatgagag ttattaacag caaaaaggag ttacctttct cgaggttaac
    18781 tcctttgttt atagataaat gttgaatagt ttagtaagtc aatacaaagt attttttctt
    18841 cccacgacgg ataacagtca gttcattttc taacttatca gcgtcactca agacatagtc
    18901 aaggtcttgg atgcggtcgc cgtttacgta gatggctccg ttttggacgt cttcacgggc
    18961 ttggcgtttt gagttaacta taccagatga gacgagcagt tccacgatat tgttgttttc
    19021 gtctgcctgt acttggtagt ttggcacacc acgaagtcct tgtttgagct ctttgacaga
    19081 aaggtttttg atgtttcctg caaagagttg ctcagtgatg ttaagtgctt ctttgtaggc
    19141 ttcttctccg tgaacaagtg taacaacttc acgagccaag actttttgag ccaagcgttc
    19201 gtgtggcgct gcttcaaatt gtttacgaat atcttcaatc tcatcaagtg acaagaaagt
    19261 aaagattttc aagaagcgaa cagcgtcagc gtccatcacg ttcatccaga attggtacat
    19321 ttcgtatgga gaagtctttt cgggattgag ccagacggca tttccttctg atttaccaaa
    19381 ttttttacca gttgcatctg tgattagtgg aacagtgata acgtgaccag tcttgtccgc
    19441 cttacgacga agcaattcgg taccagctgt catatttccc cactggtcag aaccaccgat
    19501 ttgaagagtg acattatggt cttggttaag gacgaagaag tcgtaccctt gcatgatttg
    19561 gtaagcgaac tcagtgtaag aaattcctgt ttcgatccgt tttttaacag attccttact
    19621 catcatgtag ttgaccgtga agtactttcc aatgtcacgg aggaagtcaa tgaagctgat
    19681 gctgccaaac cagtcgtagt tgttgaccat gacagccttg ttttcgccat tttcaaagtc
    19741 aagaaaacga gaaagttgtc cttggataga cttgacccag ccatctactg tgtcttttgt
    19801 ttggagacta cgttcagcat ctttgaagga cggatctccg atgagacctg tagcaccgcc
    19861 aacgagcgca taaggtttgt gacctgctag ttgcaagcga cgacttgtca agattgcgac
    19921 aaggtggcct aggtgaaggc tgtcagcagt tggatcgtag ccagtataat aagaaacttg
    19981 accttcttct agggctttac gcaaagcttc ttcatcagtc gtttgaaata tcaaaccacg
    20041 ctcttttagc tcatcaaaaa tgtgcatgtg tcttttctcc tttttaaaat tattgtttct
    20101 acctattgta tcacaaactt gggcaatagc ctagcagaat agggaagaaa gtggctattt
    20161 tattgaaaat ttcccttttg tggtataata gataaagtga ggaaatccat gcaaaatcaa
    20221 ttaaatgaat taaaacgaaa aatgctggaa tttttccagc aaaaacaaaa aaataaaaaa
    20281 tcagctagac ctggcaagaa aggttcaagt accaaaaaat ctaaaacctt agataagtca
    20341 gccattttcc cagctatttt actgagtata aaagccttat ttaacttact ctttgtactc
    20401 ggttttctag gaggaatgtt gggagttggg attgctttgg ggtacggagt ggccttattt
    20461 gacaaggttc gggtgcctca gacagaagaa ttggtgaatc aggtcaagga catctcttct
    20521 atttcagaga ttacctattc ggacgggacg gtgattgctt ccatagagag tgatttgttg
    20581 cgcacttcta tctcatctga gcaaatttcg gaaaatctga agaaggctat cattgcgaca
    20641 gaagatgaac actttaaaga acataagggt gtagtaccca aggcggtgat tcgtgcgacc
    20701 ttggggaaat ttgtaggttt gggttcctct agtgggggtt caaccttgac ccagcaacta
    20761 attaaacagc aggttgttgg ggatgcgccg accttggctc gtaaggcggc agagattgtg
    20821 gatgctcttg ccttggaacg cgccatgaat aaagatgaga ttttaacgac ctatctcaat
    20881 gtggctccct ttggccgaaa taataaggga cagaatattg caggggctcg gcaagcagct
    20941 gagggaattt tcggtgtaga tgccagtcag ttgactgttc ctcaagcagc atttttagca
    21001 ggacttccac agagtcccat tacttactct ccttatgaaa atactgggga gttgaagagt
    21061 gatgaagacc tagaaattgg cttaagacgg gctaaggcag ttctttacag tatgtatcgt
    21121 acaggtgcat taagcaaaga cgagtattct cagtacaagg attatgacct taaacaggac
    21181 tttttaccat cgggcacggt tacaggaatt tcacgagact atttatactt tacaactttg
    21241 gcagaagctc aagaacgtat gtatgactat ctagctcaga gagacaatgt ctccgctaag
    21301 gagttgaaaa atgaggcaac tcagaagttt tatcgagatt tggcagccaa ggaaattgaa
    21361 aatggtggtt ataagattac tactaccata gatcagaaaa ttcattctgc catgcaaagt
    21421 gcggttgctg attatggcta tcttttagac gatggaacag gtcgtgtaga agtagggaat
    21481 gtcttgatgg ataaccaaac aggtgctatt ctaggctttg taggtggtcg taattatcaa
    21541 gaaaatcaaa ataatcatgc ctttgataca aaacgttcgc cagcttctac taccaagccc
    21601 ttgctggcct acggtattgc tattgaccag ggcttgatgg gaagtgaaac gattctatct
    21661 aactatccaa caaactttgc taatggcaat ccgattatgt atgctaatag caagggaaca
    21721 ggaatgatga ccttgggaga agctctgaac tattcatgga atatccctgc ttactggacc
    21781 tatcgtatgc tccgtgaaaa gggtgttgat gtcaagggtt atatggaaaa gatgggttac
    21841 gagattcctg agtacggtat tgagagcttg ccaatgggtg gtggtattga agtcacagtt
    21901 gcccagcata ccaatggcta tcagacctta gctaataatg gagtttatca tcagaagcat
    21961 gtgatttcaa agattgaagc agcagatggt agagtggtgt atgagtatca ggataaaccg
    22021 gttcaagtct attcaaaagc tactgcgacg attatgcagg gattgctacg agaagttcta
    22081 tcctctcgtg tgacaacaac cttcaagtct aacctgactt ctttaaatcc tactctggct
    22141 aatgcagatt ggattgggaa gactggtaca accaaccaag acgaaaatat gtggctcatg
    22201 ctttcgacac ctagattaac cctaggtggc tggattgggc atgatgataa tcattcattg
    22261 tcacgtagag caggttattc taataactct aattacatgg ctcatctggt aaatgcgatt
    22321 cagcaagctt ccccaagcat ttgggggaac gagcgctttg ctttagatcc tagtgtagtg
    22381 aaatcggaag tcttgaaatc aacaggtcaa aaaccaggga aggtttctgt tgaaggaaaa
    22441 gaggtagagg tcacaggttc gactgttacc agctattggg ctaataagtc aggagcgcca
    22501 gcgacaagtt atcgctttgc tattggcgga agtgatgcgg attatcagaa tgcttggtct
    22561 agtattgtgg ggagtctacc aactccatcc agctccagca gttcaagtag tagttctagc
    22621 gatagcagta actcaagtac tacacgacct tcttcttcaa gggcgagacg ataattctct
    22681 aaatgaagtg gccaatcaat ggattgccac ttttttcctt tcgtgttaca ataagggtat
    22741 gaatcagtat cagaaaaaga ttgttaacgg aaaaatttat tcgctcctat ccggcttaat
    22801 atggggaatc tgtggaattt taggagagta cttctttact cattatcagg tgtcttcggg
    22861 ctggattacc tctatgcgtt tgacactggc agggagtctt gtactcattt ggtctgcaat
    22921 acaattaaaa tcgcaagtgc tagatatttg gcgagacaag aaaaattacc tgcccttttt
    22981 agcctatgct attttgggga ttttttcagt tcagtatttt ttctatctct gtttagaata
    23041 ctcaaatgct acgacagcaa ctattttaca gtttattagc cctgtcttta tcctctttta
    23101 caatcgcttg gtttatcaaa aacgagcgtc aaaaagcgct gttttctatg ttttggttgc
    23161 catgctgggt gtttgcttga tggcgacaaa gggagatctc tctcagttat ccatgacgcc
    23221 gctagctctt ataacaggtt tgctgagtgc catgggtgtt atgtttaatg ttatcttgcc
    23281 ccaacctttt gctaagcgtt atggttttgt tcctacggtt gggtggggga tgattttggc
    23341 aggtttgttt agcaatgtcc tctcgccggt ttatcagctt tcctttactc ttgatatttg
    23401 gagtatcttg atttgcctca ttatcgcttt ctttggaacg gcttttgctt ttttcatttc
    23461 catgaaggct gtgtccttgg tttctccttt ggtggtttcc gttatcagtg ccagtgaacc
    23521 tctctcttct gctctcttga gtgttttgtt cttaggatta gtagtggatt ggtccctcct
    23581 tctagctata gccttgatta ttttacccat gatatttttg tctatagaag aagcgaaaga
    23641 aagtagataa aaagtctttt cttaattcta aaagtgtgct atactagaat agtcaataaa
    23701 acacggggag atagttgtga agagtatttt taggttgtat cggtaggggc ttgcttttac
    23761 cgacagcacg ttttatctca catccctaaa aaatcatacc taaaaacaga caaaaaggtt
    23821 tcaaatttga ggcctttttt ggtagaatag gtatcattat aacgaaccag gaggcaccta
    23881 tgactgctac aaaaatgaac gctcaagaaa ttatccaatt tatcgccaat gctgaaaaga
    23941 aaaccagtgt caaagtaacc tttgaggggc aactcgcaac tgctgtgcct agctctgttg
    24001 tcaaactagg aaatgtccta ttcggagact ggaaggacgt ggctccgctt cttgaaggtt
    24061 tggtagaaaa tcaagattat gttgtcgagc aagatgctcg taattctgca gttcctttgc
    24121 tagataagcg tgctatcaac gctcgtatcg agccaggtgc tattatccgt gaccaggtgg
    24181 aaattggtga caatgctgtt atcatgatgg gagctgttat caatatcggt gctgaaatcg
    24241 gtgctggaac catgattgac atgggtgcca tccttggtgg ccgtgctatc gttggaaaaa
    24301 atagccacgt tggtgcaggt gcagttttgg caggtgtgat tgagccagct agtgctgaac
    24361 cagtctgtgt cggagacaat gttcttatcg gggctaatgc agtggttatc gaaggagtcc
    24421 aaatcggtag tggttcagtt gtcgctgcag gagctatcgt tacccaagat gtcccagaaa
    24481 acgtggtagt agcaggtgtt ccagctcgta ttatcaaaga aattgatgcc caaactcaac
    24541 aaaaaacagc gctagaggat gcgcttcgta ccttgtaatt gtaaaagtaa aaaagaggcg
    24601 gaaccctttt tccagcctct ttctgctata tcggaggaca gatagatgtt agatttgatt
    24661 cagactagac gagctttaca ccagattcca gagattggct tggaggagtt caagactcag
    24721 gcttatttgc tggatgtgat tgagaaattg actacgggca aggattttgt tcaaattcgt
    24781 acttggcgga cagggatttt ggtctacctg cagggaagtc agccggagcg aaccattggt
    24841 tggcggacag atattgatgg cctgcctatc gtcgaacaaa caggtctacc ttttacttct
    24901 caacaccaag gtcgcatgca tgcctgtggt catgattttc atatgaccat tgccttaggc
    24961 tgtcttgagc gcgcccttga ggagcaaccc aagaataatc tgctctttct atttcagcct
    25021 gctgaagaaa atgaagctgg tggtatgctc atgtatgagg acggtgcttt tggagattgg
    25081 ttgccaaacc aattctatgg tctccatgtt cgtccagatt tgaaagtcgg ccagattgcg
    25141 actaatactc atacactctt tgcaggaact tgcgaggtga agatccgttt caaaggtaaa
    25201 ggtggccacg cagcttttcc tcatgaagcc aatgacgcct tggtggcggc tagttacttt
    25261 gtgacccaag tgcagtcagt tgttagccgc aatgtcaacc caatcgaggg agcagtggtg
    25321 accttcggcg tttttcaagc tggaaccacc aacaatgtca tcacagacac agctttttta
    25381 catggaacta ttcgtgcctt gacacaggac atgagtctct tggtgcaaaa gagggtaaaa
    25441 acagttgcag aaggggttgc agctgccttt gatatggaag tcgaagtgga actcaaacaa
    25501 ggtggatacc tacctgttga gaacaatcca gccttggcgc gtgaactgat ggacttcttt
    25561 gacgagaaag acggaatcga gttgattgat atcgaacctg ctatgacagg cgaggacttt
    25621 ggttatctcc tttcaaaggt tgatggcgtg atgttttggc taggtatcga tagtccctac
    25681 gctcttcatc accctcaaat gagtcctaag gaagaagtct tagctattgg ggtggctgcg
    25741 gtgtctagtt tcctgaaaaa gaaggcagca gaatagaggg cttgtctatg aaatcggaat
    25801 tacgcaagca agtcttgcat gaaatgaagg ctatatctca agagcaaaaa caggctatag
    25861 accaagcttt aaccgagcga attttacaac acccctttta tcaagaagcc aaggtcatcg
    25921 caacctacct ctctttttct catgagtttc aaacgcggga actgattgag caggcgctga
    25981 aggacggcaa gaaggttttg acacctaaga cctatcccaa ggggcgcatg gattttgtgg
    26041 tctatgatcc gcaacagttg gtaaaaactt cctttgcctt actggagcca cagggagatt
    26101 tggaagtagt ggatgcatct cagattgatt tgattcatgt tcctggcctg gcttttacga
    26161 cggatggata tcggattgga tatggtggag gttattatga ccgctatctg gaacattttt
    26221 ctggtcgtgc tttgagtacg atatatcctt gtcaaattca ggactttata cctgaaaacc
    26281 atgatattcc tgttcaggag gtattaattg atgaaggaaa tctttgatag acgttaccct
    26341 gtgacgagtt tcttcctctt agtgacggcc ttggtatttt tactaatgtt ggtcactgca
    26401 ggcggaaact ttgacagggc agatacatta tttcgatttg gagccatgta tgggccagct
    26461 attcgcctct ttcccgagca ggtttggcgt ctcttgtctg ccatttttgt tcatattggg
    26521 tgggaacatt tcattgttaa tatgctttca ctttattatc ttggaaggca ggtagaggag
    26581 attttcggtt ctaagcagtt tttctttctc tatcttttat caggaatgat gggcaatctc
    26641 tttgtttttg tatttagtcc taaatcctta gcagcaggcg cctctacctc tctttatggg
    26701 ctatttgccg cgattattgt tcttcgctat gcaactcgca atccttatat tcaacagcta
    26761 gggcaatcct atctgacact ttttgtagtt aacattattg gaagtgttct gattccagga
    26821 atcagcctag caggccatat cggtggtgca gttggtggcg catttctagc agttatcttt
    26881 ccagttagag gagaaaaacg gatgtataat accagccaga gattaggagc ggtagtcttg
    26941 ttcgtaggac tcgccatttt gcttttctac aagggaatgg gaatgtgacg aagttgaaag
    27001 aaaatttgtg taatgaaaaa agataaggca ttttttgaac cttatctttt tattttattt
    27061 tattccttct cagtcaattc ttttccaagt tggatgaggt aattcttcaa atcatctttg
    27121 acttgtgggt gtttgagggc gtagtcgatg gatgttttca tgaagccaaa cttgtctccg
    27181 acatcgtaac gagccccatt gaactcacga gcaaatacac gttgtgtttt attgagggtg
    27241 tcgattgcat ctgtcagctg aatttcattt cctgcacctg gagcttggtt ttcgaggatt
    27301 tggaaaattt caggcgtgag gaggtagcgt ccgataatag caaggtcgct aggagcgtcc
    27361 tctggagctg gtttttcaac aaaggtttca acactgtaaa gaccatcttt tccttcgcct
    27421 tgcggagcaa taaccccgta agcagatact tcgtcatgag ggactggcat gacagcgata
    27481 gtagacgcgt gggtacgctc gtagtcatcc atgagttgtt tggtaagtgg aacagccttt
    27541 tcgtctgtga tatccatcaa gtcatcacca agcataacga caaaaggttc atttccgacg
    27601 aaagccttag cttgcaaaac agcatctccg agaccgcgtg gatgagtttg gcggataaaa
    27661 tgcagacgca tgtcagttgt tttatcaact agcttcaaaa gatctgtttt ccctttttct
    27721 ttgaggttat attccaattc gaagtttgaa tcaaagtggt cctcaataga acgttttgat
    27781 ttaccagtga caactagaat atcttcaata cctgatttga gagcctcttc cacgataaac
    27841 tggatagttg gtttgtctac gattggcaac atttctttgg caagggcctt ggttgctggt
    27901 aaaaatcgag ttcctagtcc agcagcaggg atgactgcct ttctaacttt tgatgtcata
    27961 aaaatccttt ctatagaggg ttaagaccac tcattttctg ctttaaattc attgttcatg
    28021 atgtcataaa tggcatcttt gatattggtt ccgtgataaa taacttggta aatagcctgt
    28081 gtaatgggca tatagactcc aagttcttgg gctagttcat aggctgctcg agtcgttgaa
    28141 attccttcga ttaccatgcc catattagct tctatatcag ctagggattc tcctcgtccg
    28201 agagcatctc cagctctcca gttacgagag tggatggaag ttcccgttac gatcaaatct
    28261 cccacaccag ataagccgct ataggtcaat ggactggccc cgagtgctac ccctaggcgg
    28321 gtgatttctg ctaaacctcg agcgatgatg gctgccttag cattatcacc aaatccaaga
    28381 ccatgtaaag ctccagcacc gacagcaata atatttttaa gagcaccagc agtttcaacc
    28441 ccgataacat ccgtattggt ataaagtcgg aagtagtgat tactaaatag ctcctgaacg
    28501 tattgagctg tttgtaaatc tttagaagca gcagtgatta aagttaggtc acgcacaatg
    28561 gtttcttccg catgactagg ccctgaaaca acgacaatat cactgcggag ctgttcagga
    28621 atttcttctt caaggatagt tgataatcgt ttatggctat caggttctaa tccctttgaa
    28681 gcgtgcatga tgatagcctt atggtccaag gtttgtgcaa cttgttgggc aacaagtcgt
    28741 gtcacttttg ttgggacaac aaacaaaatc gcatccacat ctttcaatgt ttctgctaag
    28801 tcggtgtagg caatgatatt ttcatctaga acgacatctt taaagtagtg cttgttagta
    28861 tgataggtat taatttcatt gatttgctcg ggaagatttc cccaaatacg tacctcgtgt
    28921 ccattgtcat ttaagacttg tgaaagggca gttccccaag aaccaggccc caagacggcg
    28981 acggtttgtt tttccatgat ttcctccttg atagagttct ttccattatt ctatcatatt
    29041 ctagaggatt ttgcacttgc attactgggg tatggtggaa aaatacacaa agaccgagat
    29101 gaagggataa actcttagtc tttagttaaa gtgagaagaa atctgataga tagtttgatt
    29161 cagtatatgc tataaataga ggtaaacaac tcaggaggtt cttgtaggtt gcgagagttt
    29221 ggcgaaaaaa ttaaaagatt acgtttggct aaaaaaatca gtcgttcaga attttgtggt
    29281 gatgagtctg aattaagtat ccgtcaatta attagaattg aaaatggaga atccagacca
    29341 acactaacaa agttaaaata tatcgctgaa cgtttggggg gggtgaagat tacaagttga
    29401 tgccaagtta tatagagttg gataaggaat acctagaatt gaagtatttc ttgatgagga
    29461 ctcctacata cgaagatgaa actatcgccc aaaagaaaga gagtgttttt gctaagattt
    29521 ttgaagagta ttatgatagg ctacctgagg aagaaagatt tatcatccca aattattcat
    29581 atctagcact agcgaactac acagttcaaa aattaccaga aaagctagtt gaaatactgt
    29641 ccttctggtg attttgctta atttctgatg ttcgagacat gattgaggag atttgtcttg
    29701 attttttcct aaaaaagggc agactcctcc cttggtttga tgctcgattt ttaaaataag
    29761 gtgacttatt ctgttaggca tgttttcccc tgccctctag ctctatatgg aacagggagt
    29821 atcagattta tctggcagat tgtatcaaat aaggcttgaa actgttttga ataggcgtat
    29881 agacttgaga atttgagaat atgtcgtcta gcagtagaga catattttcc ggcaatatga
    29941 aggaagagac gtcgaaaacg cttgatagtc aaggacttta cttcatcacc agctagctgc
    30001 tttaaaaaga ggtagagatt ataagccaga cagcccatca tcatacgtac ttcattctta
    30061 atcatggtcg aactatctgt cttatcccca aagaatcctg ctttcctttc tttgataaag
    30121 ttttcagcat tccctcgttc acgatagaat tgaaacagct cctcactatc tacactgctt
    30181 aaattgttca aatgaacttt tttacaacca taaaaaagag cacttaatcg tactcttctc
    30241 ttttaaggat tagttgaatt aattcaaatc cactagttct cctgtttcta ggtagactag
    30301 gcgttcacaa atgttagcaa tgtaatcagc gaagcgttcc agatgtccta tgatataaag
    30361 gtattgagtt ccattgggaa ttgaggtttc ttggtctttc ataagtccaa tgatttcctt
    30421 tgataaggca taataatatt ggtcaatctg ttcatctttt tgagcaatac taatagcttt
    30481 tgaggcttgg tgcaaaggaa aggcaaccaa taaatcggct agcatgctga gggataattt
    30541 acccatttgg tgtaactgtt cttcgtcagg ggctagttga ttttctttta gttgcaaaac
    30601 agctttggca atgcctgcca tatggtctcc catacgttca aggtctgaac aagaagacat
    30661 gatgctaatc acaaatcgaa ggtcagacac ttgtggctgt tgcaaggcca acaaacgggc
    30721 acaggtcaat tcgatagcgc tttgaccttg gttgatagca tgatccttat tgataattag
    30781 ctctgccatc tccttgtctt tggaggctaa ggccagtaag gcttttgaag ctgtttcaag
    30841 gacaagttgc cctagtccta aaaaggattg ttctaattca tgcaattcta agtcaaattg
    30901 atttctcata ggtttttcct tccttatccg aaccgtcctg aaatatagtc ttctgtgcgc
    30961 tgatcttttg gattggtaaa cacgtcaacg gtatctccaa attcgcaaat ttctcctgtt
    31021 aagaaaaaag cagttttatc tgaaatacgt gaagcttgtt gcatgttatg ggtaacaatg
    31081 ataatcgtat aatccttttt tagttgctga atgaggtctt caatttttaa agtggagata
    31141 gggtctaagg ctgaagtcgg ctcatccatt aacagaacat caggttctac tgctaaagct
    31201 cgcgcaatgc aaaggcgttg ctgctgaccg ccagataagg acatggcact ctttttaaga
    31261 tcatctttga cttcttccca aatggctgcc ccttttaaag atttctccac taaggcatct
    31321 aattgttttt tgtctcgaat accatgtgtc cttggaccat aagccacgtt atcatagata
    31381 gacatggcaa agggattagg ctgttgaaaa accatcccta cacgcttgcg tagctgatta
    31441 aggttgaatt tgctactata aatatcttgc tcatctaaga ggacttggcc ttcaatatgg
    31501 caagaaggaa ccaaatcgtt catccggtta agggttttta gaaaagttga tttgccacaa
    31561 ccagatgggc ctatcaaggc agtaatctgt ctttctggta attgaatcga aatatttttt
    31621 aaggcttgaa aatccccgta aaataagtct aggtgtctga ctgaaaatgt tcccatacta
    31681 ggaagctcct ttcacaagtt ttcgagataa taagcttgat agagtattta tcattaaaac
    31741 agtaataatc aaaatcacac cggtagcata ggcttcattg acatgtagcc cctcacttga
    31801 cagcatatac atatgcaggg ctagagaacg acctgaagac atgagactac ttggcgtatt
    31861 ggtagaggta cctaatgtat acatgagggc agctgtctca ccaacgatac ggccaatagc
    31921 tagtatcact ccagctaaaa tacctggcat ggcaactggt agaacaattc taaaaacagt
    31981 ccgtaactta cctgccccaa gtccataact tgcttgacgc atgctatcac taacagataa
    32041 aagggcttct tctgttgagc gaataatgac tggcaacacc atgatgactg aggttaagat
    32101 tcctgataac agagagtatt gaaaacctaa gaagactaca aagaagagca tgccaaacag
    32161 accaaaaaca atggaaggaa tcccagacaa ggtatctgag gccaatcgca tgattttaac
    32221 acaaagggaa tctttttttg tatattccac aagataaaaa ccagcaaaaa tccctatggg
    32281 caaggctaaa agaagagcac caaagaccag aataacggtg gaaataatcg ctggcataag
    32341 ggaaatgttc tcagaagtat aagtccaaga aaagagggat agacttagat gaggtaagcc
    32401 tttgatgagg ataaaaccaa tgattaaaaa gagagagcca aaggttaaag ctgaaaaaca
    32461 ataaacgaga agttttagca ggtatttact cataagatga ttttcctttc aagtaggcaa
    32521 agtaggcatt aatcaagaga ataaggaaaa agagaactgc tgaggttgca ataagggctt
    32581 ccctatgctg acctgatgcg taagccattt ccagaacaat attggttgtt aaggttctgg
    32641 ttcctgaaaa gagtccactt ggaataatcg gctggttgcc tgccaccaaa ataactgcca
    32701 tggtttcacc tactgcgcga ccgattccta aaataactgc tgataaaata ccagatctcg
    32761 cagctggcaa gatgacacta aaaatactcc gttcatgact agctcctaga gccaagctac
    32821 cagaataata cgttttggga actgttcgga tagcagattc tgacaaactg ataatggttg
    32881 gcaaaatcat tattcctaat agtaacgaag cggttaggac actcatgcca tttcctaaaa
    32941 aggttctaat ccaaggcacc aataattgta ggccgaaaaa accataaaca atagatggaa
    33001 tggccgccat caagttgata gctgatttta agaagccata gacgggcttt ggacaataat
    33061 aaaccataaa caccgatgtc aagatgcctg ttggcacccc aatcacaatc gctcctaagg
    33121 taattaataa ggaaccaacg atcattggta aaataccata gcttgccgga atgttcgttg
    33181 gcgaccaatc actgcctaat aaaaaacggg caaagccgta gttagccatg aaaggtaagc
    33241 cattactaaa aataaagaaa cagattagca aaatagctac aacagctact gttgcactca
    33301 tgaaaaaaat tgccctaaaa actgcttctt tgaaggcttg ttttgtcaca tcttgtcctt
    33361 tctagtgaag aaagtaaggg agatacgaca cctccctact tgccttcttt atcttattgt
    33421 acgatgaaac gtctgcatct ctttagagat ttatggagca aacattttat ttaatcttgt
    33481 cccaggtggt taatttgcca ctaaaaacgt ctgcaagttc agccatactg acttggcttg
    33541 ccttattgtc attattgacc acaacagcaa taccgtctaa agcaatagca tcatgggtga
    33601 gactcttacc ttcttcagga gttaattccc tagaaaccat accaatatca gcggttttct
    33661 ccttaacagc ggtaatacct gctgaagacc cattagaggt aatatcaatc gtaacttctg
    33721 gattttcttt tttataagct tctgctaatt tttccattaa agaagatact gaagtggaac
    33781 ctacaacaga caacttgcct gataagtgtt ggcttgtata ttctgtggtt tcggttttag
    33841 cttcaataaa tttattatct gtgaccactt gttgaccttg tttggagtgg ataaagctga
    33901 taaaatcttg acctagcttg gaaagattag aagaccaaac aatgttgaag ggacgttgaa
    33961 gagggtattc accatctaaa actgtgtctc gactagcctt gacaccatca atctctaaag
    34021 ccttgacaga tttcgttaaa gatcccaagg agatgtagcc gatagcatta gcattccctt
    34081 gaactgctga gagaacacct tctgtactat tttgaatcac agctgttttg gcagtgttgt
    34141 caattttttt atcaccgtct tttttgagaa tccctgtgat ttctgtgaag gcaccccgtg
    34201 ttccagagcc attttctcgt gaaatcacct caatcgttcc tgaagctgac tgtttggaag
    34261 cagctgactg attgccacag gcaacaagcc caaatcctga taagccaatg gctgcaagag
    34321 taagcatttt tttgaatttc ataataatca cctttatctc tatgtatttt tcttgtgtag
    34381 gcttactaca tttatagtct aacaagtctt tgtaaaggtt tatccctgat tcatgtaaag
    34441 attgtgtaaa gaatcaaaaa aagccacttt tgaaaaatgg ctgctcctaa aaatagcttt
    34501 aaaaattatt agtcctgtgc gaaagattgg ttaggaagaa aaatcgtgaa gcaactgcct
    34561 ctgccaagct gactcgtcac cgtgacttgg ccacctaata attgactgag ttctttgaca
    34621 atggcaaggc caagaccagt gccaccagtt tgtctgcttc gacctttatt aactcggtaa
    34681 aaacgttcaa aaatacgatc ctgctctaat tgactaatac caatccctgt atctgataca
    34741 gaaatcttaa tgccttcgtt caccttttgg gtcttgacct caatttttcc cccttgttca
    34801 gtgtaacgga tggcattgga taaaagattg agtaagattt gggaaagtaa ttgactatct
    34861 gatacgaggg tgacatcatc tggcacctgc acctttagct gtaaatcctt cttcttgagc
    34921 tgaggttgca agctttgagt caaatcctgt acaaattctg ccaaagaaag ggtcgtccat
    34981 tgtataggca tttgttgagc cttagataag gtaagaagat gctcaacaat atgctcaaga
    35041 cgcaagcttt ctttgtaaat aatgtctaga aagtcatcct tgagcgcttc ttcttcagct
    35101 gacatcccct taatggtttc agcaaagccc ttaatcgaag taactggtgt cctcaattca
    35161 tgggaggcat ttgagacaaa ggctaaattt aacttttcat aagttctaat cgttgttaaa
    35221 tcatatagca agacgagcac agcttccaca gattgggtgg ggctaaaaac gggaactgct
    35281 gtcacttcta aaatcaagtc accctcatga aacccactta cttcttgttt taaccttgtt
    35341 ttttgatcaa aggcttggtg aactaaattt cgaatatcca tccgtttgag gtcatcaagt
    35401 gaacttatgt cgccgtccac atcgggaaaa taatgaggca gagagcgact ggataataac
    35461 atctgacctt gagcggaaac taaaaacgtc cccatggtta ggtgcgacag aagaacctcc
    35521 attgtttcgg ctaggtcctt gtattgctga tcctgttggg agactttggt ttttagggca
    35581 gacacatact gagccaaaga ctttaagtct tcttgccctt tttctaaaaa gtattcacta
    35641 ctggtcaaga gaggttggtg caaggtctca aaagcaactt cccatttcca aaggcaaaag
    35701 agccagtagc caccttgtcc caaagaaagg gctagaagaa agagaccgat gcctttactg
    35761 atccaagtta atgccatccc tgcaatcaga atgaggctaa cacttagatt gactagccaa
    35821 aattgaaggt agcgtttcat ctataactcc ttgaacttat aaccataacc ccgaatggtt
    35881 cgaataaatt gaggggcttt aggattgtct tcaatttttt ccctcaactt accaatatga
    35941 acgtccacca aacgtgtttc ctgcccaaag tcataccccc agatacgttc caaaagacgc
    36001 tctctagtca gtgtcatgtt gggatgtttc ataagataga gcaagagttc aaattctttt
    36061 ggggtcaaac tcagtaactt attcgccttg tagacttcat gacgctcagg gtatactttc
    36121 aaggtcccaa atagccaaga atcgtcagcg atattatctg aatcatctcc ttcttgttct
    36181 cctttagttc gcctgaggac agccttgaca cgcgccagca attctctagg gctaaaaggc
    36241 ttggtcaggt agtcatcagc ccctaattcc aaggccaaaa ccttatcaaa ttcatcactt
    36301 ttcgcagaaa ccatcataat tggagttttg acgcctttgg ctctcagccg cttacaaact
    36361 tccatgccat ctaattgtgg taacatgata tcaagcaaga taaaatcaaa gggttctgtt
    36421 tctgccaaag ctaaggcctt ccgtccattt gttaccaatt gagtagaaaa gccttcctta
    36481 cttaaatggt agtcaagcaa tttcagaatg tgttcttcat catccactaa taagacttgt
    36541 tttgtcatct attatctcct attggtaaca ttataacaca attatcagaa atcctaacat
    36601 tgctaaatca gattaaattt gcttatcaag actagtatct ggtcaaacgc tcaatcatct
    36661 ccttgtgctc tggataggtc gccagtagat ctaccctttc aaataattca aaatcctcaa
    36721 attcaaaacc aggagcaaca agacaagaaa ccagagcata atccttatca actgttgatc
    36781 cccaaatagt gcccttagga acacagtagt gaagttgttg ccctttggat atgtccaggc
    36841 ctaaagtgac tgcttcgtag tgaccatctg ctgtaatcat gtgaacagta agtggggatc
    36901 ctgcatgaaa ataccagatt tcatctgctg tcaatcggtg aaaatgtgaa ggattcgttt
    36961 cttctaataa gaaataaata ctggtataaa gcgcccttcc cttaccagca aggtttatag
    37021 tgtctgaagc tttttttgtt tgtctaaaat agccaccttc aacatgggga gctaactcta
    37081 gagttcttat caagtcttct ttatccgtcg gagccaatgg gttgaagtaa ctcttgttca
    37141 aaggtggtgt tacgatttca agaactcctc tcagctctga ggacacgata atgattgatg
    37201 cgacggaagt acaaatcaat cgccctaaaa aaagaattag cgaattattc tggtaaaaa
//
LOCUS       DAVBEM010000017        35357 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVBEM010000017 DAVBEM010000000
VERSION     DAVBEM010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35357
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.017"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(<1..1017)
                     /locus_tag="VQ548_000868"
     CDS             complement(<1..1017)
                     /locus_tag="VQ548_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET2653743.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMKELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     KGEILEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESSEKFEAIKQNLVDEMWKVAQRELATGFYYGTPSENEQLFGARRKIPEYKFVAEVV
                     SYDDA"
     gene            1641..1823
                     /locus_tag="VQ548_000869"
     CDS             1641..1823
                     /locus_tag="VQ548_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET2653744.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            1833..2198
                     /locus_tag="VQ548_000870"
     CDS             1833..2198
                     /locus_tag="VQ548_000870"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET2653745.1"
                     /translation="MPNSENTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            2195..3385
                     /locus_tag="VQ548_000871"
     CDS             2195..3385
                     /locus_tag="VQ548_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET2653746.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RNGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(3900..4892)
                     /locus_tag="VQ548_000872"
     CDS             complement(3900..4892)
                     /locus_tag="VQ548_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2653747.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            5052..6806
                     /locus_tag="VQ548_000873"
     CDS             5052..6806
                     /locus_tag="VQ548_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2653748.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAVLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIVTPILVLVLGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAEVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAIIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            6790..8511
                     /locus_tag="VQ548_000874"
     CDS             6790..8511
                     /locus_tag="VQ548_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2653749.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERIHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            8522..9151
                     /locus_tag="VQ548_000875"
     CDS             8522..9151
                     /locus_tag="VQ548_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET2653750.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALIALGAFLGGILGAYIGKALLKKHFSNGLYCVGYFTPCLILWCYLN"
     gene            9052..9609
                     /locus_tag="VQ548_000876"
     CDS             9052..9609
                     /locus_tag="VQ548_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2653751.1"
                     /translation="MYRQGSIEKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIP
                     IVIRMFILPFMAASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKN
                     IKMAMRVRGINFKNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRV
                     KIQLIDFVYVLAVAGLIVGGLIWLK"
     gene            9597..10961
                     /locus_tag="VQ548_000877"
     CDS             9597..10961
                     /locus_tag="VQ548_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2653752.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGSGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDILEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDESSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKTSPFIFFDEPSSGIDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
     gene            complement(11644..12194)
                     /locus_tag="VQ548_000878"
                     /pseudo
     CDS             complement(11644..12194)
                     /locus_tag="VQ548_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12270..12671)
                     /locus_tag="VQ548_000879"
     CDS             complement(12270..12671)
                     /locus_tag="VQ548_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2653753.1"
                     /translation="MDSASIIAHTIHQKFNLKVPNYRQEEDWARMGLPITRKEIANWH
                     IKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSQLTYYWTFLSGKSEKQGIT
                     LYHHDQCRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(12679..12984)
                     /locus_tag="VQ548_000880"
     CDS             complement(12679..12984)
                     /locus_tag="VQ548_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase zinc-finger binding
                     domain-containing protein"
                     /protein_id="HET2653754.1"
                     /translation="MFPVETEEITYKRKKSKGKRQALLAQFDSEEVHHQVEESICSDC
                     QGDLKEIGATLQRQELVFIPAQLKRIDHIQHAYKCQACSDKNPSDKIVKAPIPKAPL"
     gene            complement(12971..13165)
                     /locus_tag="VQ548_000881"
     CDS             complement(12971..13165)
                     /locus_tag="VQ548_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2653755.1"
                     /translation="MKIIQQQSATIDSLTNALALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLNLFEEESPSEKDGDVPS"
     gene            complement(13241..13581)
                     /gene="tnpB"
                     /locus_tag="VQ548_000882"
                     /pseudo
     CDS             complement(13241..13581)
                     /gene="tnpB"
                     /locus_tag="VQ548_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(13562..13747)
                     /locus_tag="VQ548_000883"
     CDS             complement(13562..13747)
                     /locus_tag="VQ548_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653756.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(14051..15613)
                     /gene="guaA"
                     /locus_tag="VQ548_000884"
     CDS             complement(14051..15613)
                     /gene="guaA"
                     /locus_tag="VQ548_000884"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HET2653757.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            15755..16453
                     /locus_tag="VQ548_000885"
     CDS             15755..16453
                     /locus_tag="VQ548_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2653758.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(16496..17392)
                     /locus_tag="VQ548_000886"
     CDS             complement(16496..17392)
                     /locus_tag="VQ548_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET2653759.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLLIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(17401..18336)
                     /locus_tag="VQ548_000887"
     CDS             complement(17401..18336)
                     /locus_tag="VQ548_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HET2653760.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(18333..19058)
                     /locus_tag="VQ548_000888"
     CDS             complement(18333..19058)
                     /locus_tag="VQ548_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HET2653761.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(19142..19777)
                     /locus_tag="VQ548_000889"
     CDS             complement(19142..19777)
                     /locus_tag="VQ548_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HET2653762.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(19779..20606)
                     /locus_tag="VQ548_000890"
     CDS             complement(19779..20606)
                     /locus_tag="VQ548_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2653763.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(20628..20964)
                     /locus_tag="VQ548_000891"
                     /pseudo
     CDS             complement(20628..20964)
                     /locus_tag="VQ548_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
     gene            complement(20965..21681)
                     /locus_tag="VQ548_000892"
     CDS             complement(20965..21681)
                     /locus_tag="VQ548_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HET2653764.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISMADII
                     EKAGITPIGVYTHEPRDQAPLVIKEVNAIKVALLAYSYGFNGIEQYIFQEDYNRYLSD
                     LNEDKIKAEVERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSKTVEKDGDKKLIIY"
     gene            22204..22815
                     /locus_tag="VQ548_000893"
     CDS             22204..22815
                     /locus_tag="VQ548_000893"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET2653765.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEGIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            22860..23588
                     /gene="rlmB"
                     /locus_tag="VQ548_000894"
     CDS             22860..23588
                     /gene="rlmB"
                     /locus_tag="VQ548_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HET2653766.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFLNRL"
     gene            complement(23627..24538)
                     /gene="trxB"
                     /locus_tag="VQ548_000895"
     CDS             complement(23627..24538)
                     /gene="trxB"
                     /locus_tag="VQ548_000895"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HET2653767.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(24604..24828)
                     /locus_tag="VQ548_000896"
     CDS             complement(24604..24828)
                     /locus_tag="VQ548_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HET2653768.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(24906..25649)
                     /locus_tag="VQ548_000897"
     CDS             complement(24906..25649)
                     /locus_tag="VQ548_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2653769.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILLLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(25649..26449)
                     /locus_tag="VQ548_000898"
     CDS             complement(25649..26449)
                     /locus_tag="VQ548_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2653770.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(26607..26963)
                     /locus_tag="VQ548_000899"
     CDS             complement(26607..26963)
                     /locus_tag="VQ548_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET2653771.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(26976..27488)
                     /locus_tag="VQ548_000900"
     CDS             complement(26976..27488)
                     /locus_tag="VQ548_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HET2653772.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(27488..27982)
                     /locus_tag="VQ548_000901"
     CDS             complement(27488..27982)
                     /locus_tag="VQ548_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2653773.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            28117..28563
                     /locus_tag="VQ548_000902"
     CDS             28117..28563
                     /locus_tag="VQ548_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HET2653774.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            28560..29207
                     /locus_tag="VQ548_000903"
     CDS             28560..29207
                     /locus_tag="VQ548_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HET2653775.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(29228..29809)
                     /gene="pdxT"
                     /locus_tag="VQ548_000904"
     CDS             complement(29228..29809)
                     /gene="pdxT"
                     /locus_tag="VQ548_000904"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HET2653776.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(29810..30685)
                     /gene="pdxS"
                     /locus_tag="VQ548_000905"
     CDS             complement(29810..30685)
                     /gene="pdxS"
                     /locus_tag="VQ548_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HET2653777.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(30837..32216)
                     /locus_tag="VQ548_000906"
     CDS             complement(30837..32216)
                     /locus_tag="VQ548_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET2653778.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKDKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            32511..33434
                     /locus_tag="VQ548_000907"
     CDS             32511..33434
                     /locus_tag="VQ548_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HET2653779.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            33494..34099
                     /locus_tag="VQ548_000908"
     CDS             33494..34099
                     /locus_tag="VQ548_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2653780.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKTIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLTHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            34117..>35357
                     /locus_tag="VQ548_000909"
     CDS             34117..>35357
                     /locus_tag="VQ548_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2653781.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRNFKFKFELEVLEIDEVPMF
                     NQDEKWDESFQLRFLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGAS"
BASE COUNT        11288 a         6992 c         6290 g        10787 t
ORIGIN      
        1 cgcatcatca taagaaacca cttcagcgac aaacttgtac tcaggaattt tacgacgagc
       61 accaaacaac tgctcatttt cagatggtgt accatagtaa aatcctgtag ccagttcacg
      121 ttgggcaacc ttccacatct cgtccactaa gttttgtttg atggcttcaa acttttcaga
      181 actttcaaga taggcatcca cagccgcctt gtagcagttg gttactgttg atacgtagtg
      241 aatagacttc atacgtcctt cgatttttag actgtccaca ccattttcaa tcatatctgg
      301 aatgtggtca atcatagaca tatcaacggc tgacattgaa aattcttcta gaatctcacc
      361 cttcaaactc ttacgttctt tcccaaatgg catatcgtaa aggtcgtatt tccaacggca
      421 tgactgagaa cacccaccac ggttggcatc acgcatactc atgtggtttg aaagagtaca
      481 acgtccagag tatgaaatac acatagctcc atggacaaag gcttcaattt caacatctgt
      541 acgtttgcgg atttcagcta attctttcat tgaaacctca cgtgctaaaa cgacacgagt
      601 caagcctagc tctttccaga actcaagggt ttcatagtta gtggcactgg cttgggtaga
      661 aaggtggatt tcaaggcctg gtgcttcagt cgctgcaatc ataatcaagg ctgggtcaga
      721 tacgataact gctgcaatcc cgatatcacg cagtttacga aaccactcac cagcaccagc
      781 ttcatttcct tcgtgcataa ccatattagc cgctacatag accttggcac catacttggc
      841 cgcaaactgc acgccttctt ccatctgttc gaaagtaaag tttcccgcac ggctacgaag
      901 accataggcc tgaccaccga taaagacagc atctgctcca tactgaacag ctacctttag
      961 cttctctaaa gtccctgcag gtgataaaac ctcaggacgt tttaatgttt ttgtcatgat
     1021 ttctcctatt tgcaatataa aagtttgaca tttttccttc tcattttata gtaaataaag
     1081 gataaaatca agcctagacg gattgttttg acaattctaa tcttttagac tttgcataat
     1141 aactattaaa cagtcgaaaa ttaccccagt tttaacaagt agtcaaaaag tctaaaaaag
     1201 taaaaaccag tatcccaaga tactgactcg taaaaatata taaattagtc cttagatgac
     1261 tactcccact ctgttgctcc tataatggaa aaggattgat acagtctaga atatcgcttt
     1321 tttatttatt attctgatat aaaactgtta gaattgattt tttgttttat acccaaatat
     1381 gaatagagac gtagctaata agttgaataa catatttgga aaaatgagaa atagcaatat
     1441 tactagaact tttagaaaca atcaatattt aaaaagaaaa aagctcaaag aatttattaa
     1501 accatgttat aatagatata gctataattt tatttataac aagaggatag aaatgaccga
     1561 attagaaaga aaaaatcgaa aaattagcta agaaatattc tgataactta aacatcaaag
     1621 ttcaagagag agttcgtgaa atggcaaatg ataataagag ccattatttg atatacagag
     1681 ttttaggtat ttcatttgaa gaaggagaaa atatcgattt gtatcaaaat aaaggtcgtt
     1741 ttttatacaa atatgctggt tcatttttag aagaagctgc agtactatcc tttaacgaaa
     1801 aatttggtac agaaaatact taaaaagtta acattcctaa ttctgaaaat acaaaaccta
     1861 agacttttga aattgattgt ttagtcggag aaaaacacgc atacgaaata aaatggtggg
     1921 atgcaactac agatggagac catataacta aagaacacac tagaataaaa gttattcata
     1981 acaaaggata tataccaatt cggttaatgt tctactatcc aaatagaact caagctataa
     2041 aaattcagca aactttagaa acattgtata acggtattgg agggaaatat tattatggag
     2101 attctgcctg ggaacattta agagcagtga ccggtattga tttacttagt attctaacag
     2161 atattgcaaa taaaaaaaca ggggtaaaat caaaatgaca gtattaaaag gagataactt
     2221 agaaatatta aaaactattg aatcctcaag tattgattta atctatatgg accctccttt
     2281 ctttacacag aaaacccaaa aattatctaa taacaaaaat attatgtatt cattcgaaga
     2341 tacgtggact tcgattgagg attacaaaga atttttgtct gtaagattag aagaatgcaa
     2401 aagagtgcta aaaaatagtg gcagtatttt cgttcattgt gataaaattg caaatcatca
     2461 tattagatta attttagata atatctttgg agcagatatg tttcaaagcg aaattatatg
     2521 gaactataaa cggtggtcta attcaaaaaa gggattattg aacaatcatc aaaacattta
     2581 cttttattca aagtcaaaag attttaaatt taatacaatt tttacagagt attcttctac
     2641 tacaaatatc gaccaaatac tagtagaacg aaaacgaaat ggaaactcta aaactatata
     2701 taaagttgat aataatggta actatattct agcaaaagag aaaaatggag ttcccctttc
     2761 agatgtttgg aatataccat ttcttaatcc aaaagctaaa gaaagagtag gttatcctac
     2821 acaaaaacct attctgttat tagaacaaat tataaagatt gctactgata aaaatgatat
     2881 agttttagac ccgttctgtg gaagtggaac tactttagta gcctccaaga ttttgaatag
     2941 aaattatatg gggattgatt tatctgagga agctatcaat ataactcagc aacgtctgga
     3001 aaatgttata aaaacaagtt caaatttatt gaataaagga atcgaagcat atagaaccaa
     3061 aactgaggaa gaggaaaaca ttcttaaatt attacaggca aaaattgttc aaagaaataa
     3121 aggaattgat ggttttttac ctaaacattt tcaaaaaaaa ccgataccta taaaaattca
     3181 aaaaaataat gaatgtctga atgagagtat ctctttatta cagaatgcta taaactccaa
     3241 aaaacttgat tttggagtag ttataaaaac tcattcagat aatttattat ttgattttga
     3301 tacgattcct gaaaatataa tagtagttga ccattttgaa cttacaatcg aaaaatggtt
     3361 aagtaaaagt caacagttac tatagtttgc aaattattta cagaaagaac aaaaaatgct
     3421 ctgaaacact gatttcaagg cattttttgt tagtttaaaa ttactcccat tcttcttttc
     3481 caaacgtaca atatatccaa aaccattcaa aatactagat tctatttttt ataatatcac
     3541 taaatccacc taattatagg acgttttcag atttttagtc ccgtcccagt cccagtaccg
     3601 gagaaatatt gttttaatat aatatctctt tttgtcttct aagctcttaa aagcaaaaga
     3661 acaagtaaag agtcaagaca aggataaaaa gtccatatta gggcaaataa aaagctttaa
     3721 gacagatgac aaatctaagt caaataagaa agaccatagc aaaggtgcag agagataaat
     3781 attggcggtc ttcggactgc ctttattttt ttatccattt ttcaaatcaa atttattcag
     3841 actatatatg cacatataca cttaaattca tataaaaaca tggcttgtaa aaaattactt
     3901 taatcacaat aatcgcattt aaaattgtga tgtttgcaag ctaaattacg gacttcactt
     3961 ggaagttttc ccttgtatct tttataatag atagaaaatt tgctggcaga tgaatatcca
     4021 acagattctg ctatctcttt tataggtagt tcagtgttta aaagaagagt ttcagctaca
     4081 ttcattcttt ttctttgagt gtactctgta atgctttgac aatatttttc cttaaataaa
     4141 ttttttaatt tagtaccact cattttagat attttttcaa gcgtgccttg atttacattc
     4201 gttgcaaaat gatcatctaa gaatcttgct acatcttcaa gtgctttatc atcatcaatt
     4261 tcaattttat atttttttct atttaagtat gtgtcaatta ctatacttat ccattcattt
     4321 gcctttgctt taaagaaaaa atcagcggca ggagcgtcca tcttacaatt taatatttcc
     4381 attgccactc tttctaaggc ctttgtaagt attatttgat tcggttgaag caaggttgaa
     4441 taaaaagatt ctggattaat gttaatagat gctaaatgtt tttctattag ctctttttta
     4501 aaaccaatgg aaacagcaag ataacaacaa ttctcgtgta ataaaaaaac aaaatcatct
     4561 tttatattat caaaatcaaa agtacataaa gagtttgcgg taatagtttg atacggatta
     4621 aacttttctc cgtttgcact gacaatgtaa cttgaataaa ttgaaacata gtctgacata
     4681 ctataagtgc tattttgaac tacttcctct ttgatataaa aatcatgtat atcgataatg
     4741 aagctgcctc cttcataaaa ccaatatagg ccttctgcat aagttgaatt ctcttttttc
     4801 caacaaaatg tatgacctgc acttgaatac ttctcattgt ttttacattc atctactttc
     4861 atataatctt ttacaaaatc ataatatgac ataacacact atccctttta gacaatattc
     4921 caattagcct tattaattca aaactattgt attagtaatt ataacagatg tataatagaa
     4981 aagcaatgat agatattatc aattaagcga atttatatct aaaagggata ttaaagaaag
     5041 gagatatgct tatgaagatt tacaaaaaac tatttgctta tgtccaagat aagaaatatc
     5101 ttggggtttt ggccataatt ttttctgcta tatctgctgt acttacagta tatggatatt
     5161 atttaatcta caaatttcta gataagttaa taattaattc aaacttatcc ggtgcagaga
     5221 gtatagcatt aaaatctgtt attacactaa caagtggagc gatattttat tttgtctcag
     5281 gaatgttttc acatatcttg ggatttaggc ttgaaacaaa tttaagaaaa aggggaatcg
     5341 atggtctgga aaaagcaagt tttaggttct ttgacttaaa tccatctggt caaataagaa
     5401 agatcataga tgataatgca gcacaaactc atcaggtggt agctcacatg attccagata
     5461 gctctcaggc aatagtcaca cctatacttg tccttgtact tggctttata gtaagtataa
     5521 gagttggcat aattttgctt gctcttacta taattggtgg cttaatttta ggggcaatga
     5581 tgggcgagca agaatttatg aagatatacc aagaatccct atctaaacta agtgctgaaa
     5641 ctgttgagta cgtgagagga atgcaagttg taaaaatatt taaagcaaat gtagagtctt
     5701 ttaaaagctt ttataaggcg ataaaagatt actcaaagta tgcttatgat tattccctat
     5761 cttgtaaaag gccttatgtt ttgtatcaat ggttattttt tggactgatt gcaattttaa
     5821 ttattcctat agtttatttt atgactagct tagctagcgc agaggtgatt ttacttgagc
     5881 ttatcatgat tttattttta tcaggagttc tctttgtttc attcatgaga atgatgtggt
     5941 actccatgta tatttctcaa ggaaattatg cagtagatac tttagaggcg ctttacgaag
     6001 atatgcaaaa agacaaatta gtgcatggta atgtcaataa ttttaaaaac tataatatag
     6061 aatttgagaa tgttagcttt gcttataatg ataaagctat cattgaaaat ttatccttta
     6121 atttagaaga aggaaagtcc tacgcacttg tcggttcatc tggatcaggc aaatcaacag
     6181 tagcaaaact tatatcaggt ttttacaatg ttaataaagg aagcataaag ataggcggga
     6241 tagcaataag tgaatattct gacgaagcct taattaaagc catttccttt gtttttcaag
     6301 attcaaaatt attcaagaag agcatttatg ataatgtagc tttagctaat aaagatgcga
     6361 cgaaagatga cgttatgaga gccttaaaat tagcaggatg cgatttaata ttagacaaat
     6421 tcccagaaag agaaaataca atcataggct caaaaggtgt ttatttatcc ggtggagaaa
     6481 aacaaagaat tgcaattgct agagcaattt taaaggattc caaaattatt attatggatg
     6541 aagcatcagc atctattgac ccagataacg agtttgaatt gcaaaaagct tttaaaaatc
     6601 ttatgaagga taaaacagtt atcatgattg cacacaggct atctacaatt aaagaccttg
     6661 atgaaattat tgtcatggat agtggaaaaa ttatagaaag agggtctgac aaagaattaa
     6721 tgtcaaaaga tacaaggtat aagagcctgc aagagatgtt taacagtgcg aatgaatgga
     6781 gggtttcaaa tgaaagagtt ttataaaaaa agatttgctc ttacagatgg aggagcaaga
     6841 aatttaagta aagcaacact ggcttcattt ttcgtttatt gtataaacat gcttcctgcc
     6901 atattactta tgatttttgc tcaggaagtt ttggaaaata tgggcaaaag caatggcttt
     6961 tatatagtat tctcagtttt gactttgata gcaatgtata ttttgctttc tatcgaatac
     7021 gataaattat ataacacaac ctatcaagaa agtgcagatt taagaataag gacagcggag
     7081 aatttatcaa aattacctct atcttacttt tctaaacatg acatttccga catttcacaa
     7141 acaatcatgg ctgatattga aggcatagag catgcaatga gccactcaat accaaaggtg
     7201 ggcggcatgg tactgttttt cccattaata tctgtaatga tgctagcggg caatgtcaag
     7261 atgggtttag ctgtaattat tccatctatt ttaagcttta tatttatacc tttatctaaa
     7321 aaatatcagg ttaatggaca gaatagatat tatgatgtct taagaaaaaa ctcagaaagc
     7381 tttcaagaaa atatcgaaat gcaaatggag attaaagcat ataatttatc gaaggatatt
     7441 aaagatgact tatataaaaa aatggaagat agtgagagaa tacacttaaa ggcggaagta
     7501 actacaattt taactttgtc tatatcttca atatttagct ttatatctct tgctgttgtg
     7561 atatttgtcg gcgtaaatct aattattaat aaagagataa attctctcta ccttatagga
     7621 tatttactag ctgctatgaa gataaaagac tctttagatg catctaaaga gggcttgatg
     7681 gaaatatttt atttatcgcc caaaatagaa agattaaaag aaattcaaaa tcaagattta
     7741 caagaaggcg atgactatag cttaaaaaaa tttgatattg atctaaaaga tgttgagttt
     7801 gcctacaata aagacgcaaa agttttaaat ggtgtaagtt ttaaagctaa gcagggagag
     7861 gtcactgctt tggtaggtgc aagtggctgc ggtaaaacaa ctatcttgaa acttatatca
     7921 agactttatg attatgacaa gggacaaatc ttaatcgatg gcaaagatat aaaagaaata
     7981 tcaacagaat ctctttttga taaggtctct atagttttcc aagatgtggt tctctttaat
     8041 caaagcgtta tggaaaatat tagaatcggt aagcaagatg caagtgacga agaggttaaa
     8101 agagcagcaa aacttgcaaa ttgcacagat tttatagaaa aaatggataa aggtttcgat
     8161 acagttattg gtgaaaacgg agctgagcta tcaggaggag aaagacaaag attatcaata
     8221 gccagagcct tcttaaaaga tgcgccgata ttgatcttag atgagataac agcaagcctt
     8281 gatgttaaca acgagaaaaa gattcaagag tctttaaata atttagttaa agataaaact
     8341 gttgtaatca tttcacatag aatgaaatcc atagaaaatg cagacaagat agtagttctt
     8401 caaaacggaa gagtagaaag cgaaggtaag catgaagagc ttttacaaaa atcaaaaatt
     8461 tacaaaaatt taatagaaaa gacaaaaatg gcagaagaat ttatttatta ggaggactac
     8521 aatggataat aaaaaattaa aagtaaaaga tttagtaagt atcggtgttt ttggcgtaat
     8581 ttattttgcc ttcatgtttg gagttggtat gatgggcttg attccaatat tgttcttaat
     8641 atacccgaca gtattagcca tagttgcagg aactgttgtt atgttattta tggctaaggt
     8701 tcaaaagcca tgggcactat ttatatttgg tatgatatca ccacttgtga tgtttgcagc
     8761 tggtcatacc tacgtagttg tggttttatc acttatagta atgataatag cagaattaat
     8821 tagaaagatt ggtaattata attcatttaa atacaatatg ctttcttatg caatcttcag
     8881 cacatggata tgtagctctt taatgcaaat gcttttagca aaagaaaaat atatggagtg
     8941 gtctttgatg acgatgggaa aagattatgt tgatgtatta gaaaagttaa taacttatcc
     9001 tcacatggct ttaatagcct taggtgcttt cttaggagga attcttggag catatatagg
     9061 caaggctcta ttgaaaaaac acttttcaaa tggattatat tgtgtgggat actttactcc
     9121 ttgcctaatt ttatggtgtt atctgaatta aaccctatag ttaagatgtt tttgagtata
     9181 cctattgtta ttagaatgtt tattttacca tttatggcag caagctttat gataaagacc
     9241 tcggatgtag gcgcaataat ttcatcgatg gataagctta agatttcaaa gaatgtatcc
     9301 atacctattg cggttatgtt tagattcttc ccatctttta aggaggagaa gaaaaacatc
     9361 aaaatggcta tgagagtaag agggataaat tttaaaaacc cagtcaaata tcttgaatat
     9421 gtttctgtgc cactactcat tatatcatct aatatatcag atgacattgc aaaagcggca
     9481 gaaacaaagg caatagaaaa tccaattgcc aagaccagat acattcgcgt aaagatacag
     9541 ctaattgatt ttgtttatgt tttagcggtt gctggactta ttgtgggagg cttaatatgg
     9601 ttgaaataaa aaatttaagt cttgattatg gtgaagagca tatattagat gatatatcac
     9661 tatccatagc cgagggagag tgcgtgctat ttacaggaaa aagtggaagt ggtaagtcat
     9721 ctttaataaa ttcaatcaat ggactagctg taaggtatga taacgcaaag acaaagggcg
     9781 aaataattat tgatggtaag aatataaaaa atttggaact ttatcaaatc tcaatgcttg
     9841 tttcaactgt ttttcaaaat cctaagacat atttttttaa tgtcaatacg acattagaat
     9901 tattatttta tttggaaaat atcggtcttg caagagaaga gatggacagg cgtttgaagg
     9961 atatacttga gatattcccg ataaaaaatc ttttgaacag aaatatattt aatctatccg
    10021 gcggtgaaaa acaaattctt tgcattgcag cttcttatat agcaggtaca aagattatag
    10081 ttatggatga gtcttcatcg aatttagata ttaaaagcat aagtgttttg gcaaagatgc
    10141 taaagatatt aaaagagaaa ggcataagca taattgttgc agagcataga atttattatt
    10201 tgatggacat agttgaccgt gtatttttaa tagataaagg aaagcttaaa aaaacttata
    10261 ctagaagtga atttttaaag ctagataaaa atgaattaaa tgctttaagt ttaagagata
    10321 aagaattaag taaattaaaa gttccttatt taaaagaagg tggagagtat cagataaaaa
    10381 atcttagcta caaatttact gatgatgagt gtttaagctt aaaagatatt tcgttcaagc
    10441 ttgggaaaat ttatggcata ataggatcca acggacgagg aaaatcaacg cttttaagat
    10501 gtttaatagg tcttgagaaa aaatcaaaag aagaaattta ttttaaggga gagaagctat
    10561 ctaaaaaaga aagactcaaa aactcttcac ttgttatgca agatgtaaat catcaattat
    10621 tcacagatga agtattcaac gagcttagat taggagtaaa gaattttgat gaagaaaagg
    10681 cgaaaatcat tttaaaagat ttaggcctgg acgaatttat tgaaaggcat ccgatgagtt
    10741 tatcaggagg gcaaaagcaa aggcttgcaa tagcatctgt tatgtgcaag acttctccat
    10801 ttatcttttt tgacgaacct tcaagtggta tagattattc caatatgata aaaatatctg
    10861 aactgattaa taagtataaa accatggata aaataatttt tattgtttcc catgatatag
    10921 aatttttaaa tgaagtggca gatgaaattt ttgaattgta aaatagagtc tgttaaacat
    10981 gtctatagaa ctggtaaatt gtctaaaaat ttaaaagata ctaacacata ttgatattta
    11041 ttagaaaatt aacttcagga tttttacagt atttataaac tttataatat gtatttatag
    11101 tattaataat ttccatatct ttagggaaat tatttattta cttaccataa ttaaagagat
    11161 gagagataaa tatcggcagt cttcggactg cctttatttt tttacttaat ttaatgcagt
    11221 aaatcatacg attgaaagga atctgcgtta tatgctataa ttaggtagtt aatctataca
    11281 tttagaaagg taaaatatag aattggagaa tgatatggga ttttcatata ataaattgta
    11341 accacccaat aacgaagtct attgaaaaat ctccagatta gtgaactcac ggatagttcc
    11401 taatctggag atttcttatt tgcacttttc ttgtacaact ttagtccatg gtaaataagc
    11461 ctctaaaacc tctttgttta cgagagtttc ctcgtttgga agacattcta gaagatagga
    11521 tagatatttc tcgctattta taatggattg aaataagata tgaacaaatc gattaggaaa
    11581 ggaaaattga tttatagaaa tattttagca gtcgatgcgt actgttatag attcaacgca
    11641 ctataattga tgacgtttag ctgtttccaa caaactcata ataatagctc ttgctttagc
    11701 tccttcaaaa ctttgagaaa ataaccaccc tcgctttttt aaactgagct taggctaaaa
    11761 gagtccactg gactctttta ctccgtccca taaccaatga tttaatggcg cattcagcta
    11821 gattattgga aaggaccaga tgtccgtctt tcaaaatagt cttaaaggtt tctttatact
    11881 tgaggctgta ttcaattgcc cttcctagtt ttgaacccga taaaactgac tgacgccggc
    11941 accaagcaaa gaaatcttcc attaggttgg agctcttctt gacgtttctg tagtcgttca
    12001 tcagctggca aagcctccca gtctctttcc aagaaaaata actgatcaca ataagctaaa
    12061 cctttagctc ctaaggatga tttatccgct tgcttggggg tcgcttcaaa aaacttcctt
    12121 ctcacatgcg cccaacatcc aacaagtgca gcttcttcca gttgacgata agcttctagc
    12181 ggttcgcagt ttaccaagct tagcgtcgcc ttgctcctaa accttggact gctatcgcat
    12241 aggcagaact agaggactaa agtcctaagt tactgccgca acatatcaca atgcacatag
    12301 ccagaataat ctcctaggaa ttcttgtact actgaaccac ttcgacactg atcatggtgg
    12361 taaagcgtaa tcccttgttt ctctgattta cctgacaaaa aagtccaata gtaagtcagc
    12421 tgactatcac tttctaagac ccgataagag gtttcatctg catgaagaag aggttgttct
    12481 aacaactttt ctcgtaaaag gttataaagg gactctaaat agtattgact cgccttgata
    12541 tgccaattag caatttcctt acgtgtgatt ggtaaaccca tcctagccca atcttcttct
    12601 tggcgataat taggtacctt cagattaaac ttctgatgga tggtgtgagc gataatagaa
    12661 gctgagtcaa tagtctcgtt ataaaggggc tttaggaata ggagctttca caattttatc
    12721 actcggattt ttatcactgc atgcttggca tttgtaagcg tgttggatat gatctatgcg
    12781 ttttaattgc gcaggaataa agactaattc ttgtcgttga agggttgctc caatctcttt
    12841 tagatctccc tgacaatcag agcaaatgct ctcttctact tgatgatgaa cttcttctga
    12901 atcaaattgg gcaagaagag cttggcgttt ccctttagat ttcttacgtt tgtaggtaat
    12961 ttcctctgtt tcaactggga acatctccat ctttctcaga tggagactct tcctcaaaaa
    13021 ggttgagttg tccagagggg caaacacttt tctcagagga ttttccatag agcttttgag
    13081 tcagataagc cacttgttca cgaagaaggg caagtgcatt ggtgagacta tcaattgtag
    13141 cactctgttg ttgaatgatt ttcaatcttc ttccatgggc ttcccctcct tgttttctac
    13201 ctttattata ctaaaaagaa agtcctcatt tcaatagaaa tcacgacttt ctgatggatt
    13261 tatttttgga gtgatagaaa agtccttcat aagccagtct acttgttcag atgtgagagc
    13321 tttgacatcc ttttctgtac tgggccaagt cagtctgccg ttcccaaagc gtttatatag
    13381 tagccaaaat ccttgaccat cccagtaaag ggctttaaag cggtatttac gtccaccaca
    13441 aaagagaaaa acttgacctg agaaaggatc taattcaaag tgggttttaa ccagataagc
    13501 cagtgaatca atgccttgcc tcatatccgt tttcccacat acgagataga cctgccctag
    13561 gctagataga tgaattgtca tagagcaaca ccttatccaa aagctgttct accatttcga
    13621 gattgagaga ttgaaaaaaa cttacttcaa gcttgccaat acgaatttta agcagaatat
    13681 catttctctt tttagaatca aaaggacgag attgtggaat ctctacagga acaataggtt
    13741 gtggcattaa aatatcctcc aatagtttta ctttactaat agtatacagg aggaactcca
    13801 tgaatgatag ataccttgtt atgacgcgat tactatatta gaaagttggc tctctaatta
    13861 aattaattct cattatatat atcaaaagac cgcagcttga aaactacggt ctaatttttt
    13921 gtccaaatgt aaaccacttg gaactattat tcaatttatt ctttttagta aatgttcccg
    13981 ttttaatccc agttacagtt tttaatcctc tgtaaccgtt gattttacaa agcttttaat
    14041 ttttttgcga ttattcccac tcaactgttg caggtggttt acttgtaata tcgtagacga
    14101 tacggttaac atgatccact tcatttacga tacgtactga gattttttga agtacttccc
    14161 atggaatttt ggcaaaatca gcagtcatac catcgataga agtgatagca cggattgcaa
    14221 tcgtgtagtc atatgtacga ccgtcaccca taacaccgac tgaacgaacg cctgtgttaa
    14281 cagtgaagta ttgccaaata tcgcggtcaa gtccagcttt agcgatttct tcacgaagaa
    14341 tagcgtctga ttcacgaacg gtttcaagtt tctcttcagt gatttcaccc atgacacgga
    14401 tagcaagtcc tggtcctggg aatggttggc gccatacgat atggtctggc ataccaagct
    14461 ctgtaccaag agcacgaact tcatccttgt aaagagtatt gagtggttca atcaattcaa
    14521 actgcatatc ttctggaaga ccacccacgt tgtggtgtga cttgatagtt tgagctgtat
    14581 ccgtaccaga ctcgataaca tctgtatata aagtaccttg agcaaggaat ttcacatctt
    14641 tgagcttgct tgcttcgtca tcgaatacat agacaaactc gttaccgatg attttacgtt
    14701 tttgttcagg atcagaaacg ccagcaagtt tgtcaaggaa acgtttagca gcgtctgctt
    14761 tgacgatatt caaaccaaac ttaccaccga gcatgtccat aacttgatca gcttcgcctt
    14821 tacgaagaag accgtggtct acgaagatac agatcaattg atcgccaatc gctttttgga
    14881 gaagaacccc aacgacagat gagtcaacac cacctgatag accaagaagg acacgtttat
    14941 caccgacggt ttcacgaatt tttttgatct gcatgtcaat gaaattatcc attgaccagt
    15001 cacctttagc cttacaaatg ttaagggcaa agttacgaag gatatcattt ccgtatacag
    15061 aatgacgaac ttctgggtgg aattggatac cgtaaatgtg tttatctggg ttttcgatgg
    15121 ctgcgtatgg gcagtcagct gatgtacctg tacgaacaaa gtcagcagga atctcagtaa
    15181 ccgcatcacc atggctcatc aaaacagtct gttcatcagg tgttgattca aaaagcgctg
    15241 atggtgtgtg agttagggtt gattgaccgt attcacgatt tccagcatca cctgcaggaa
    15301 caacttttcc tccaagttta tgggtcaata actgcatacc ataacagatt cccaaaattg
    15361 gaattccgag ttcgaagatt tctgggtcaa tatcaaatga accatcttca tatacagaat
    15421 ttggaccacc tgatagaata attcctacag gattgacttc acgaacttca gcagctgaaa
    15481 ttttatggct ttttagttct gaaaaaacac caatctcacg gatacggcgt gaaatcagct
    15541 ggttgtactg gctaccatag tccaatacga tgattttttc tacatcttgc aaatcagttg
    15601 aaatgttgct catctttttc ctttctcaaa agaaatatct tttctcaata ttctatcaca
    15661 aataagggcg aattaccaac taaacaaggc gaagtttgac tttttctagt ttattggggt
    15721 acaatagaga aaagatagaa atgaagtgaa aaatatgcta cctgcttata tgaaaatcca
    15781 tgatcagata aaaaaggata ttgacgagca ccgttgggct attggtgaga ggcttcccag
    15841 tgaaagagat ttagctgagc agtttgcggt cagtcgcatg accctccgcc aagccgtatc
    15901 tctattagtc gaagaaggcg tcttagagcg ccgtgtagga agcggcacct ttgtttccag
    15961 tactcgagta caagaaaaga tgcgagggac aaccagtttt actgaaattg tcaaatccca
    16021 aggtaaagtt ccctctagcc agctcatttc ctacaaaaaa accattccca atgagcaaga
    16081 agttgccaag ctaggaattt ttccaacgga caatattatc cgaatggagc gggtccgcta
    16141 tgccgaccaa gttcccctag tttatgaagt tgcttctatt cctgaaaaat tcattaagga
    16201 ctttaaaaaa gaagaaatca caagtcattt cttccaaacc ttgcaaaaac atggctatcg
    16261 tatcggcaaa tctcaacaga ccatctatgc tcgccttgct aaagaaaaga ttgcccacta
    16321 tttggaagtt gaaaaaggac atgctattct tggattgacc caggtttcct acctagaaga
    16381 tggtactgct tttgaatacg taaaaagtca atatgtaggc gaacgctttg aattttatct
    16441 tgaaaataat tagattacca cgcaaaaact ctctgtcacg gacaaagagt cttttttatt
    16501 tttctaagaa taaatctttc aaagaaatca aagttacagc aaacaatatc attgccatac
    16561 caagaaaatc aatgggataa aattgttcat tcattattaa gaaggcaaag aaaatcgccg
    16621 atattggctc aattgaagcc aacaagcttg acttgaccgg tcctatcaga ctggctcctt
    16681 taaggaaagc tgtataggca aagacagtcc cgataaggat aatgcctgca aacgcaagga
    16741 gaaaatcaag actagtcggg atatcggcct gtagaacccc tgtaaaagga agggcgacca
    16801 aacctgctat gaccattccc acaccaatga gcaagctgct cccccacttt ttaatcaagg
    16861 ctatgggtaa aatgatatac agagcataag tcaaggcaga aaagagaccc cagaacagac
    16921 cagcaggtgt catggataac tggtccaact gcccatgtgt tgcgatcagg aaggttcctc
    16981 cgatggcgaa tatgatggaa actatctctc ccagtgtcgg tgccacccta tccttgatac
    17041 agctataaat taaaattccg acaggacaaa catactgaag caccgtcgct gttcccgcat
    17101 tggtctcctg aatagcagac agataggcga attggttgag aaaaagacca atcagagcaa
    17161 aaataagaag agacagcaaa ctctttctat cctttaaaaa gaccagtatt ttatcctttg
    17221 cagtagcata agccaagagc atgagaattc caccagcgat taaaagacgc aagttggtca
    17281 agaccagagc cgaaattccg tgtgccatta ggtattggcc actcgttcct gacaaccccc
    17341 aagcaatacc agccacaact gttagtaaag tcccttttaa actatttgac atgtctctcc
    17401 ttactcttct ttgcgaatca agttcatcac ttgattgcgg tctaatatcc attgagctct
    17461 ctcgtccttt tcataggtac gattcgatag gaaaatagtg gcttcttgct tctgacgatt
    17521 ccacatgata aaggtacctg tatagcccgt atggtctagc caatctcctt ccaaattcca
    17581 tgctaaagaa cgttccttgt catccaaagg agaaaaattt tgatttaagt ctcttgcaaa
    17641 atcatctgct aaatagtgtt ctaaaaagat ttgtaaatcc tttatagtcg aaaataaacc
    17701 agcactccca gcatgtctac ccaggagacg agccttggga tcatgcacta tgcctgcctc
    17761 tacacctcta actgttggaa cagcaagctc aactggccca aacttggttt ccgtcattcc
    17821 ccaaggtttc cagacttgat cctttaaaat cacatccaaa tcttgattaa aaattctttc
    17881 caaaataaag cccaacagca aaaaatggac atccgaataa agaaaggctg gctgacttcg
    17941 tctgttgaga tgaaacatcg cttcctttaa ttcaggggct gttaaaagat cacgattagg
    18001 aataaaagga tcaaggtctg ttgcatgagt caagagctgg cgaatagtga tgtctggata
    18061 atcactctca ggtaaaaaat ctattaccag tctatcaata tctaattgac ctatttccca
    18121 caagaaggta caaactgtgc caaccccaac aaccttgctg acactagcta gatcataaac
    18181 tagtcctgcc tcagtctgca agccatgctc tgggtcactc tggcctaaat agaactctgt
    18241 ccattgattg tccttaaaat acgcaaaaga ggctccggga taaattcctg cctcgatttg
    18301 ttcttctatt tttttaataa tcttggtcca cttcatactt cttcaaacca caattcaaca
    18361 ttatttctat ctttaccaag gaagaatttt tcagacttag gaataaaata ttcagtagac
    18421 tcaaacttct ggcgaagact tgctatgtct aattcattga ccaagaactt gagcatagat
    18481 aagtcccagg taaccgtatt gtccacagtc aaatcctgcc cctgagctgg aataaaatca
    18541 agggatgccc caatttcaga tgattccaag aaactttcga tatcagttgg gagatgtaat
    18601 tccatagaaa tctcaaattt acttaaagaa attgatgcca aatctgtttg aaattcaggc
    18661 ttttctccta cttctactag acttgctctg tcatcttccg catgaatcaa aatcaaatca
    18721 tcttctggtg agaaaatttc aaaagcgtag ccattttgac ctttatataa tcgatgaatc
    18781 gaatctgttt tagataagat tccttcaatt tctaagggat tttccacctt gacaatcaat
    18841 ctagctagtt tttttcttcc ctctacctta cgagtacgca tactgggagc ttcttctaaa
    18901 accagctttt caagacccgt ttggtcacct agtgacagaa aggccgattc ttctaacaag
    18961 gccttcattc caagggtttc aatataaaat gtttcattta attttctatt attagctttt
    19021 aaagtaggaa taatccgtac aatctgattt acattcataa attcctccgt cactttttat
    19081 tttaaaggat tttagaattt tttacaagat attatgctca aatttaacat tatttagcta
    19141 tttagtaaag atagtctttc aaggattttg acaaagcctg ataaccagca atactgaggt
    19201 gcagtccatc agttgtatat tcttttttga gttggcctgc ttggtctgtc aaacaatcaa
    19261 atactggcac aaattccacc tgcatatagg cagatgcaag ctcttgatag gcttgattcc
    19321 agttctgaat tttttcattc gagcggatat agactgcctg ctggtactcc tctccctcat
    19381 tgacaggcaa aatggaaagc aatttaatct ctgtcaatgg ataatcgcga gcaacggatt
    19441 gaatgatagc ttcgagatta ttgagagcct cattcacagg aacatccttt ccgatatcat
    19501 ttgtcccaat cagaagaaaa attttatcta ctgctccacc atatagatga gcatcaagat
    19561 tctctagtaa cagtcctgtc tgatagccac gaattcctcg attgacaatc gtctttgaag
    19621 tcccaaatag ctcctgtaga ggataatact cgacaatgga atccccaata aaaagaatgt
    19681 ttggttctac aacagaaatg tgatttaggt gacgatactt agtttgaatt ttttcttgtt
    19741 cctttaggag ccaattttct aataactgta ctgccacttc attctccttt ttctaaccag
    19801 ttttccaaga cttgataaac tcctccttgg ctgttggctg gtgctagagc agtcgccaca
    19861 gctttggctt tctcatcagc attttccatc gcataggcaa ttccagccat ttcaagcatt
    19921 tcaacatcat tttcactatc accaaaagcc atgatttctt gggatttcaa gtcccagcgc
    19981 ttgagtaatt cctccaagcc ccatgcttta tgaatcccag cttggaggat atcaatgcaa
    20041 ccatagccac tggatacagc tcggacacgg ccatcaaaga gagcattgat ttcttccaaa
    20101 accgaactca aacgttcctc accaacaacc atgctcatct tgagcacacc accaaagagg
    20161 tcagatgtta attcatccac aaattgcatc cgttggtaga atttttcaat catttctgga
    20221 gtcataaaac tttcaagatc tgtaaaaatc gtaccttcct tgacaaaatc acccttcatc
    20281 cccgttacaa caaactggtc ctgacacgct cgacccttga aatgagccaa agccttgttg
    20341 acaatggcgt catcccatgt ctgagcctga atcaattcat tgttttcaaa aatacgagcg
    20401 ccattagcaa caaccagaac cactcgatcc accaagggac tcagtagttg tctcatgcgg
    20461 tgaatttcat tgcccgtcgc aatgacaaaa cgaatgcccc tttgatccaa ctgatctaaa
    20521 atcttttcca atcgtgggag atcaagctga cccctagcat ccagcaaggt cccatccata
    20581 tctgtcgcaa ttaccttaat catcatttac tttcctctgg attcaagcta ataccacttc
    20641 aatcccacat gttcattcat ttctttatag gctgtatcaa ttcgttcctt agtcgcttca
    20701 tctaactggt cacgatgact gccacccctc tataaaatct tccaaaatat aagtttggta
    20761 atgatacaag ggatatcctt ctggtgaaaa ggttcccttt ggtgttcgat tgacccaagt
    20821 aggatgagct ttagctgttc cgatagttgt ttttccatcc ttcttcttga tggtgacatc
    20881 catgagaaca ccacgttcag tccacttagc attctcttca tctcccatag attcaatccg
    20941 ttgattggaa atgaagttcc ccatttaata gataatgagt ttcttatctc catctttttc
    21001 aaccgtttta gatggttcaa caacgtgagg atgccctcca aagataatat ccgctcccca
    21061 atcgatcatc ttgtgataaa gagctttttg ttcttcagtt ggttccaatc gatactcaac
    21121 acccatctga ggcatgataa tggtgatatc tgcttccttc tctgcccgtt cgacttcagc
    21181 ctttatctta tcttcgttta aatctgaaag ataacgatta tagtcttcct gaaaaatata
    21241 ctgctcaatt ccattgaaac cataggaata ggctaacaat gcaaccttga tagcattcac
    21301 ttccttaatg accagcggag cctgatcacg tggttcgtgc gtataaactc cgattggagt
    21361 gattccagct ttctcaataa tatcggccat tgaaataact ccctcaattt gcgaatccaa
    21421 aatatgatta tgagctaaat ccagcacatg ataacctgct tccttaatag catccataac
    21481 ttcaacagga gcattaaaga gaagataacc cgctaaataa tgatccttat taatggttcc
    21541 ttcaaaatca ccaatagcta aatctgcttg cttgagccaa ggagtcacat actcaaaatt
    21601 ttcatgaaag tcataggtac cgtcttcttt tttagctgaa aagaaaagtc catcgtggta
    21661 gagcaaatcc ccgtgggcca taattctggc agttttttcc tcttcctact cctgagactt
    21721 ttgcttagtc ccctcttgag aaatagtatc tcgtttttga ctagtcaagg gattccttgg
    21781 aagctttcaa acaacaagac caagcccatt gataaaccaa ctgctagcaa gagtatcgcc
    21841 acaaatccct tattgctcca cttgcgataa ctcctaaaaa gtttaccaag cccttcataa
    21901 aacgaaaagc taaaccaccc tgatttcgat tttgtcttct ttgtatcttc attctcccta
    21961 ctttcttatg caagcctttt ctttttatta tatcacagat aagtatttct ttcacaattg
    22021 aattgaactt cccatctatt ttctataaat cctaaatgcc ataatgcttt caattcttgt
    22081 cattttgtga tatcatgtag aggtaatgaa aggaaatgaa ctaatccaca gtggcttatt
    22141 ccaagtatac cacttgggct ttggcagtag ttaactgcac taaacataat ataaggagag
    22201 aaaatgtctg caatagaacg tattacaaaa gctgctcact taattgatat gaacgatatt
    22261 atccgtgaag ggaatcctac tctacgcgcg attgctgagg aagtcacttt ccccctatct
    22321 gaccaggaaa tcatcctagg cgaaaagatg atgcaattcc ttaaacattc ccaagatcct
    22381 gtcatggctg aaaaaatggg actccgcggt ggtgttggac tggctgctcc ccagttagat
    22441 atctcaaaac gcattatcgc tgttttggta cctaatattg ttgaagaagg cgaaactcca
    22501 caggaagcct acgatttgga aggcattatg tacaatccaa aaatcgtctc tcactctgtt
    22561 caagatgctg ctcttggcga aggagaaggt tgcctgtctg ttgaccgtaa cgtgcctggc
    22621 tatgttgttc gccatgcccg cgttactgtt gactactttg acaaagatgg agaaaaacac
    22681 cgtatcaaac tcaaaggcta caactccatt gttgttcagc atgaaattga ccacattaac
    22741 ggtatcatgt tttacgatcg catcaatgaa aaagacccat ttgcagttaa agatggttta
    22801 ctgattcttg aataaagaaa atcccgttgc aagacggggt tttgtgttat aatagaggca
    22861 tgaaaacaaa tgatattgtc tatggtgtcc acgccgttac cgaagccctc cttgcaaata
    22921 caggaaacaa actctacctc caagaagatc tccgaggtaa gaatgttgag aaagtcaagg
    22981 aactagctac agaaaagaag gtgtccattt cttggacatc aaaaaaatct ctctctgaga
    23041 tgactgaagg tgctgttcat caaggttttg ttctacgagt gtctgaattt gcctatagcg
    23101 agctagatta catccttgca aaaacacgcc aagaagaaaa tccacttcta ttgattctag
    23161 atggtctaac cgatccccat aatctgggtt ctatcttgcg aacagccgat gcgaccaatg
    23221 tttcaggtgt catcattccc aagcaccgtg ctgtcggagt aactcctgtc gttgccaaaa
    23281 cagccacagg tgctattgaa cacgttccaa ttgcccgagt gacaaacctc agtcaaacct
    23341 tagataaact caaggatgaa ggcttctgga cctttggaac ggatatgaac ggtactcctt
    23401 gccacaagtg gaatacaaaa gggaaaatcg ccctcatcat cggaaatgaa ggaaaaggca
    23461 tctctagcaa catcaaaaaa caggtcgatg aaatgattac cattccgatg aatggacatg
    23521 ttcaaagcct caatgccagt gttgctgcag ccattctcat gtacgaagtt tttctaaata
    23581 gactataaaa aagtttccag tcatctgatt ggaaactttt ttatgattaa ctatgttctg
    23641 tgataaactt gtaggcttct tgaccagcga tagctccatc tccaactgct gttgttactt
    23701 ggcgaaggtc tttcaagcga acatctccaa ctgcaaagat accgtcgact gcagtcttca
    23761 tgtggctatc tgtcacaatc cagcctgcct gatcttggat attcaattct ttaacaaaat
    23821 cgctaagagg gtccaaacca acatagataa agacaccacc gaaggcttgc tctgtcactt
    23881 gacctgtttt cacattttca aaaacgacag attctactct gttttcaccc ttgatttcct
    23941 tcactacaga atcccagata aagctgattt tttcattcgc aaaggcgcga tcttgtaaaa
    24001 ccttttgggc acgaagttgg tcacgacggt gaacaatggt aacagtctta gcaaaacgag
    24061 tcaagaagag ggcttcttca acagctgaat ctccaccacc aactaccaat aaatcttggt
    24121 cacggaagaa agcaccatca cacacagcac agtaagaaac accacgactg ttcagttctt
    24181 cttctccagg cactcccaaa ggacggtgtt tagaaccagt tgctacgata actgtacgtg
    24241 tttcatatgt ttggtcatca gtcatcactt tcttaaaatc accatggtct tcgacatttt
    24301 caacataacc ataaatgtgc tcaacaccaa gattttcaag tggttcaaac atcttttcag
    24361 ccaattcagg tccactaata ttagcgtatc ctgggtaatt ttcgatatca gatgtattat
    24421 tcatctgacc acctggcaga ccaccttcaa tcaaagctac ttttagattg cttcgagcag
    24481 catacaaggc cgcagtcatc cctgcaggtc cagcaccgat aataatagta tcgtacatat
    24541 agattccttc tttcttgttg taactatctt tattctaact ctttcttgtc aatcacgcaa
    24601 ggattatgcc ttgaaaacaa gaattaaact cataaccgca aaggataata ctgggacaac
    24661 caagactcca atcataatca tatcatagag atgggcttgg cgagccctgg ctgtcttatc
    24721 aactcccgac atggctctca gaccaatcca aatccctaaa aaaatcagaa caaggatggt
    24781 ggtcaagatc aaactctcga aatataaaga aaatagttgc agtagcatga tttctctcat
    24841 ttctatcttt tttaaagagt aaactcagct agtccaacta actgagtttt cctttatcta
    24901 ttatatcaaa tataagtccg tttgtaacta gcgaagaatt cttttgtccg ctcttcttta
    24961 ggggtgtgga taatctcatc cggagttcca gactcgatga ttttcccctt atctaataag
    25021 agaattttat ccgcaacttg ggctacaaag gacatgtcat gactgaccaa aatcatggtc
    25081 tgacctgact tagcagcatc tgcaatagac ttttctactt caccgaccaa ttctgggtca
    25141 agggctgaag ttggttcgtc taagagcaaa acatctggtt tcatagcaag cgcacgcgct
    25201 agggcaaccc gttgcttctg tccacctgat aaatggcgag gataatggtt ttcacggtcc
    25261 gaaagcccaa ccttagccaa ctcttccttg gcaatcttag tcgcttcttg gtcagataat
    25321 ttcttgacaa caaccaagcc ttctttcaca ttatcaagtg ctgttcgacg ttcaaataaa
    25381 ttaaactgtt ggaaaaccat agacaactta cggcgtaggg caaggatttc ttcttgagtg
    25441 attttagaaa aatcaactga aaaaccatca atctgaatag agccactgtc aggtgtttca
    25501 agataattga gactgcgaag aaaggttgat tttccagctc ctgaagaacc aatcaaggct
    25561 acaacttccc ctttttgaat atccaagttc agatgatcca agacagtctg tcctgaaaag
    25621 gatttgctta aattcgaaat cttaatcatt aacgaaggtc tcctttcaca tctgtttgca
    25681 ctgtatcagg tgcagaaata gccatttttc tctcgatgaa acgaccgagg ctttcaattc
    25741 cgatattgac tacccaataa acaagggcaa cagagatgaa gcgttcaaaa tagcgataat
    25801 cagctccacc tagaatctga gcttgggcaa agacttccac aacacccgca ctaaaagcta
    25861 gagatgttcc cttggtcaaa ccgatgaggg aattaatcaa ggttggagta gctaccaccg
    25921 ctgcattagg aataatcact cgtcgataaa cttgcgctcg ggtcataccc agactgcgcg
    25981 ccgcctcaat ctcaccagga ttaactgaga gaatggctgc acgaatggtt tcactagcat
    26041 aagctgcctc attaaaggca aaagcgacaa tcgcaaaagc tgcagctgga atcgcattga
    26101 tattgagacc agttccccat tgctgattga gggctttcaa agccaaaggg attccgtagt
    26161 aggtcaacat gagttgcacc aaaatcggtg tcccttttaa gaaactaaca aagaaggcct
    26221 gcaagggata taaaatcttg acacgattga tcttcacaat ggcaaaaaga agcgccaaaa
    26281 ccaagccaaa aagggcacca ccaattgtca acataattgt tgttggaagt tgttggacaa
    26341 ttctagggat tccatcaaag accgaacgta ggctaaacag cttgccatcc ggaatcaatt
    26401 gcatcaagtt ttggtaccaa tctgatgcta aaatcgttgt aacattcata aaaacatcct
    26461 cttctgataa tgattcattc taccatgctt ctgccgtcaa tgaaattatt tgctacggtc
    26521 agatacagac tttgtctacc tactagttta tcatactttg aaacagggaa gttatatatt
    26581 ttatctatca aagagataga taaaaactat ttcagtccca gttcttcata agattttcga
    26641 taaccgattt gcttaacagt tccattttct actaaaatgg gccgttttaa caacataccg
    26701 tcacttgcta gcaactcagc cgcttcttgg tttgacaaac ttcctacctt atcttttagc
    26761 cctaattcac ggtatttgat accactggtg ttgaaaaatt gcttcaattc aaatcctgag
    26821 gtttctagcc aattcaaaat gacttcttgg ctaggtgttt cttccacgat atggacggct
    26881 ttatagtcca cacctaattg atttaattct tgttttgctt ttttacaagt tgaacatttg
    26941 gggtattcga taaattctaa catgtgcttc tccttctatt tgtttatatc tttaaaatct
    27001 acgccttcat gctccaagag ccaagctttc ttttccactc ctgcagcata gcctgtcaga
    27061 cgcttgcctg ctcccaacac acgatgacaa ggtactagga tagaccaagg attgcgtccc
    27121 actgctccac caattgcttg agcagaagcc acttgcaggt cttgagcaat ttgtccatag
    27181 gtcactgtct gaccataagg aatgccctgt aaatagtccc aaactctctt ttcaaaattc
    27241 gttccgattg gcgccaagag caagttggat aaatcctgag gcttgccttt aaagtaatca
    27301 tctaagcaag caataactgg gtctaaaata ggatgactaa caacttcttc tatcgtttca
    27361 tctcctagtc ccctctcaaa atgcttctgc tcctgaaccc aaattccata caaataatgg
    27421 tcatcagcta caagtgatag aataccaatt ggtgaggagt agagtatttt tacatacttc
    27481 ttttgcatta tttctttaat ttttgatagg ccaagcgttc gccatctact ggcaccttac
    27541 caacttgttt aaaaccaagt ttttcaaaaa tatgttgcat aaccttgttt tcagcatgcg
    27601 tatctgagcg aaaatcaaga taatcaaaac cttcaatcaa gccctctaag aaggtttgag
    27661 caactccttt tccctgcaca tctgctgcca cagcaatacg gtgaaagact agatactctg
    27721 actctccagc ttgccagttt ccctcataaa tagcttcata ggcctcctct ggactcttgg
    27781 tcacagcagc ataggctagc agttctccct cttccaaggc tacgtaggct tgccctgaga
    27841 tgatatcatc gataataaca tctgcatttg gatagccatt ttgccactgg tcactaccag
    27901 catctgctaa acattttttg gcatcctcca tcacctgcat gatggcatct acttcatttg
    27961 gaaaagctaa acgaatttcc atcttttttc ctcatttctg actagtttct cccatcatag
    28021 cataatttaa gtatttctac aagcagttaa aacttgactt tgtgtttttg ttattttata
    28081 atctagttat caaaactata taaaaaggag ttgaaaatga aaactacctt ttcctaccca
    28141 aaatgggcag aaattccaaa cattgacctc tatctggacc aggttttgct ctatgtcaat
    28201 caggtctgcg cccctatctc tcctaataaa gacaagggcc taacagcatc tatggtcaac
    28261 aattatgtga aaaatggtta cctgacaaag cctgacaaaa aaaaatacca acgccaacag
    28321 attgcccgtt tgattgctat cacaaccctc aagtctgtat tttctattca agaaatagcc
    28381 cagacactta atactctaca aactcaagca agttcagacc aactctacga tgcttttgtg
    28441 gactacatga accaaggaat tgacccagct aaccctatta tccaaaccag ctgccaaacc
    28501 gtcaaactct atcatcaaac tctagactta atcgatcata ctcaagagga ggtaatccaa
    28561 tgaacactag tcttaaactc agcaaacaac tcagttttgg agaggagatt gctaatagcg
    28621 tgacccatgc tgtgggtgca gtcatcatgc ttatcttgct gcctatttca tccatctata
    28681 gttatgaagc acacggattt ttatcctcta tcggcgtttc cattttcgtc atcagtctct
    28741 ttctcatgtt cctatcatcc accatttatc actctatggc ctatggttcg acccacaaat
    28801 atgttttgcg aatcattgac cattctatga tttacgttgc cattgccggc tcatacacgc
    28861 ccgttgtctt gaccttgatg aataactggt ttggctatct gattattgtc atccaatggg
    28921 gaacgaccat ctttggtatt ctctataaaa tctttgctaa aaaggtcaat gagaaattta
    28981 gccttgctct ttacctgatt atgggctggt tggttctggc tatcattcct gccattatca
    29041 gtcaaacgac acccgttttc tggagtctca tggtaactgg cggactctgt tatacagttg
    29101 gagctggatt ttatgccaag aaaaaacctt atttccacat gatttggcat ctctttatcc
    29161 tagctgcgtc cgcacttcaa tacatcgcta ttgtttatta catgtaaaaa agttgagaaa
    29221 ttcaatctca acttttttct ttacacatat tgataaagta ctggtgcaag cgcacatcat
    29281 cagtcaattc tggatgaaaa gaacttacca acatattttt ttcttgggct gcaacaattt
    29341 gattgttcac tgttgctaga atttctacac cctcaccaac actactgata atcggaccac
    29401 ggataaaggt cattggaatc ttgccaactc ccttacattc tgcttccgtg tagaaacttc
    29461 ctaattggcg cccataagca ttacgctcga ccaccatatc catagttcct agatgactct
    29521 ctttctgaga agtgatttcc ttagccagca aaattaagcc cgcacaggtc ccaaacactg
    29581 gtaagccaga tagaatggct tctcggatgg gaagtagcat gttctggtca cgtaagagct
    29641 tgcccatggt tgtagactca ccaccaggca aaatcaaacc cgacaagtca ctctgatctt
    29701 gctgaaaatc atctagattt ctgagttcta cactctcgac acctaattga tctagcactt
    29761 ttgcatgttc tgcaaaggcc ccttgcaagg ccaatattcc aattttcatc tattttcctc
    29821 gttcagccat gagaatttgg atttcatttt cattaatacc aaccatggct tctcctaaat
    29881 cttcagagat ttgagctagg atttgaggat tacggaagtt agtcacagcc ttaacaatgg
    29941 cactcgctcg tttaacagga tctcctgact tgaaaatacc tgaaccgaca aagaccccct
    30001 ctgcccctaa ttgcatcatt aacgcagcat ctgctggcgt tgcaacacct ccagcagcga
    30061 aatttacaac tggcaatttt ccatgttcat gaacatattg gaccaattct acagggactt
    30121 gcaaatcctt ggcagcaaca taaagctcgt cctcacgtaa gttttgaatg cggcgaattt
    30181 cctgattcat catacgcata tgacgaacag cttggacgat atcccctgtc cctggttctc
    30241 ctttggtacg aatcatggaa gcaccttcag cgatacgacg caaggcttca cccaaatcct
    30301 tagcaccaca gacaaaagga acttggaatt ctttcttgtc cacatggaaa cggtcatcag
    30361 ctggagatag aacttcactc tcgtcgatat aatcaatttc aatagcctct aaaatctgag
    30421 cttcaacaaa atgcccgatt ctgaccttag ccattactgg aatactaacc gcttcttgga
    30481 tttccttaat catctttggg tcgctcatgc gggaaactcc tccagctgca cgaatatcag
    30541 ccggaattcg ttccaaggcc atcacagctg ccgcaccagc agcttctgcg atacgagcct
    30601 gttcaggatt ctgcacatcc ataataacac cacccttgag catctgtgcc aagtttttat
    30661 ttagttcata acgattttca gtcatttgtt ttatcctcat catttgtatt ggtagctacc
    30721 ttttcatttt aagtcagaac agaatgaagc acaagataaa aaaactataa ttgtatgggg
    30781 acagattggc taaaaactat ctgaccttaa cttaaggcca gatagctcat tcatttttat
    30841 ttttcagccg taagggcagc cattgtgatg tagttgtatg gtttattgaa gtgtggcaag
    30901 aagaagaggt ctgtcaatgc caatttatca attgtcacat gctcttggat agcaagtgag
    30961 aacatgtgga ttcccatgct aattgcaata tcatgtgaaa ccatttgggc accaagaatt
    31021 tcacggctat ctttgtcaaa gacaatctta attgctactt catggttgtc atgtttcatg
    31081 aattctggtt tttgaagatc gttaaagcct gtttcagttg cgttgtaacc agcagctttc
    31141 gctttttcaa gagtcaaacc agttgaaacc atgtgaagac cgtagattga gataccattt
    31201 gaaccttgaa caccgattcc ttccaattca tgtccacaag cgttgtaggc accaacgata
    31261 ccagtgcgaa cagcatttga agcaagagcg atatagcttg tatctttacg agcattgtca
    31321 taaacagtcg cacagtcacc aacagcgtaa acgcctggga tagatgtttc ttgtttcttg
    31381 tctacaagga aggcaccgtt gcggaagagt tcgatcttac catcagcaag ggctgtgttt
    31441 ggacggaaac caactgcaag gataaccata tccacgtcaa agctttcttt gtcagtaatc
    31501 aagcgttcaa ctttaccatc accttcgatt gctttaacag tttgacctag agccaagcgg
    31561 atgttgtgat cttccaagtt cttcgccatc atttgtgtga agtctttgtc atagtaaccg
    31621 ttcaagacag tatcaacgat atcaacaagg acaacttctt ttccaagacg ttcaaaggct
    31681 tcagcaagtt caacaccgat gtaaccacca ccaacaacgg cgatacggtc gagatgttgg
    31741 ctcttgtcag aaagtttatt gataacttct tcagcatttt ggtacaattt cacgaattgt
    31801 acgttttcaa gagttgcttt aaattcgcgg tttcctttaa caatttcaac accttcgatt
    31861 ggtggcaaga ttggtgtaga acctgtagcg aaaatcaatt tctcgtatga ttctttgtgt
    31921 tcttttcctt caacttctgc tgtaaccact ttgttatcat agtcgattga aagaactggt
    31981 gaattcatat aaaccttagc acctttagct tctaatttgt ctttatcaga atagaacaag
    32041 ccttcagcac cgtcaatttg ttcaccaatc caaagagcca ttccacatcc taggaaagag
    32101 atgttagagt tttggtcaaa tacaacaatt tcgttctcat ttccaaaatt atccaacatg
    32161 gtattgatac atgctgtacc agcgtggtta gcaccgacta caacgatttt actcataaaa
    32221 aatttcctgc cttcattcta aatttacttt actagtatac catttaccgt tagcgtttac
    32281 aaggggggga ctattatttc agcatttttt atcaaaaata attccccatt tatcctgttt
    32341 tcaagcctca tgaattttat gagcatattt cttgactttt tccaaatttt gtttgtgaaa
    32401 attctaactt tatggtatta taataacatg aaaataaaat gtaagggctt caatttagat
    32461 gattatttga tattgcaact tattttctat aagagaaagg agttggtagc ttgactcttc
    32521 gttcacattc tgaacggcta atggggacta ctatcactat ttcattagtg gatgagcaag
    32581 ccgatatctt tctccaaaaa tcctttgact tgctcaaaga gcttgaatac cgcttcaacg
    32641 ccaatagtca agaatctgag ttgatggaaa tcaattatca agcaggaata tcccccgtca
    32701 cagttcatcc agacctgttt gagctgattt cacttgggtt agagcatagc ctagcgctct
    32761 ctagccacct caatatcagc attggtccct taattcaaac ctggcgtatc ggtttttcag
    32821 atgccaaggt cgcccagcct caagaaattg aatcggtgct gcctctaatc aatcctcatg
    32881 gtatcgagtt agattcttct acttctactg tgtttttaaa acagaaagga atgaagatcg
    32941 atctaggttg tttagccaaa ggatacagtg cggataaggt tgcccaattt cttaggaaag
    33001 agggggtgac ttctgccttg atcaatctgg gagggaatat cctgaccatt ggaaaaaatc
    33061 aggcaagagg ggataaccca tggcaaatcg ggattcaaga cccagccaat cctaggggaa
    33121 atcatttaat gaccatccct gttgtcaata aatctgtcgt gacttcaggc atttatgaac
    33181 gtcacctgac cgtcgatgga caagattacc atcacatttt tgacagtcaa acaggatatc
    33241 ctgttgaaac ggaactagcg agtctaacaa tcatctctga taaatcagtc gatggcgaaa
    33301 tctggacgac tcgactcttt ggagaaagac ctgcttctat cctctggcaa gtcgaaagtt
    33361 tggagggcat cgaagtcatc ctcatcgata aagaaggcca cctaagctgt tcttcaggaa
    33421 ttcctactct atagagacaa ctgtttcaat ggaattttaa aattgtatta tgtaaaaaga
    33481 gaaaggaaat atcatgttaa aacttattgc tattgttgga acaaattcaa aacgttctac
    33541 aaaccgtcaa ttgcttcaat acatgcaaaa acactttgct gacaaagctg aaattgaact
    33601 tgttgaaatc aagaccattc ctgtcttcaa caaaccagct gacaagcaag tacctgctga
    33661 aatattggaa attgctgcta aaatcgaaga ggcagatggc gttattatcg gtactcctga
    33721 gtatgatcac tctattccag ctgttttgat gagcgctctt gcttggttgt cttatggtat
    33781 ttacccactt ttgaacaaac caatcatgat tacaggtgct tcttacggta cgcttggttc
    33841 atctcgtgcc caattgcaac ttcgtcaaat cttgaatgct cctgaaatca aggcaaatgt
    33901 tcttccagat gaattcttgc tcacacactc tcttcaagca tttaacccaa gtggcgactt
    33961 ggttgacctt gatgttatca agaaattgga tgccatcttt gatgacttcc gtatcttcgt
    34021 gaagattact gagaaattgc gcaatgcgca agaattgctt cgcaaagatg ctgaagactt
    34081 tgactgggaa aatttgtaag ataggagacc gaaagaatga aatttgttgg acttgttgga
    34141 tcaaactacg atcaatcata taaccgcaaa ctcttggaat ttatccgtcg caatttcaaa
    34201 ttcaaatttg aattagaagt acttgaaatc gacgaagttc caatgtttaa ccaagacgaa
    34261 aaatgggacg aaagcttcca attgcgtttc ttgtataaca agattacacg tgctgatggt
    34321 gtcattatcg ccactcctga gcacaaccac actatctcag cttcactcaa atctgtactt
    34381 gaatggcttt catacgaagt tcatccattt gaaaacaagc ctgttatgat tgtgggtgca
    34441 tcatactatg accaaggaac atcacgtgct caagttcacc ttcgtaaaat ccttgatgct
    34501 ccaggtgtta atgcctacac gcttccaggt aacgaattcc ttcttggtaa agctaaggaa
    34561 gcttttgata acaacggaaa tatcaccaac gaaggcactg ttaaattcct tgaaacttgc
    34621 ttagataact ttgttaaata cgtaggagtc gtttcgaaat tgaaaaaacc aaaaccaatc
    34681 gaatcagaag acttggattg tggaaaacca atcgctacaa ccatcacaga agttgaccct
    34741 gacgatccag aatgggtaga aaaagttgca gcaatcactg gtgctgtttc tggtgatacc
    34801 tatgtcaaat tggaccacgg tatcctaaca gttaaccaaa ttgatatgtt cttgaaagct
    34861 atgccatttg aattgacata cgctgacgac aacaaccaat tcctctacta caacaacgct
    34921 caccaagatc cagacactat gttcgctaaa cgtgtaccac ctcaatcagg tagccgtatg
    34981 tcgactgttc atggttctct tccaccagca cgtatgaaga acgtagagtg ggttatcgga
    35041 acacttcgca acggaaacca agaatacgtc cgtacgatcg ttccaggttc tcctgcaggt
    35101 gttatcaaca ctcacaacta ccaagcaatg tactatcctg atggatcata cgctggtatc
    35161 aatgaaatcg tctttaactt ccaaccatgg cttgactggt acctaaaaga gactggtcaa
    35221 cgtttggtgg gtggtagcgg accatttgct cctgctgccg gaggtcatgg agacgccgat
    35281 gctacttctg gcgcttctga ttcaggggat gctggaggcc acggtggtga cgcagacgct
    35341 acagccggtg caagtta
//
LOCUS       DAVBEM010000018        34466 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVBEM010000018 DAVBEM010000000
VERSION     DAVBEM010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34466
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.018"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            143..361
                     /gene="infA"
                     /locus_tag="VQ548_000910"
     CDS             143..361
                     /gene="infA"
                     /locus_tag="VQ548_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HET2653782.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            386..502
                     /gene="rpmJ"
                     /locus_tag="VQ548_000911"
     CDS             386..502
                     /gene="rpmJ"
                     /locus_tag="VQ548_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HET2653783.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            520..885
                     /gene="rpsM"
                     /locus_tag="VQ548_000912"
     CDS             520..885
                     /gene="rpsM"
                     /locus_tag="VQ548_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HET2653784.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            903..1286
                     /gene="rpsK"
                     /locus_tag="VQ548_000913"
     CDS             903..1286
                     /gene="rpsK"
                     /locus_tag="VQ548_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HET2653785.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            1329..2264
                     /locus_tag="VQ548_000914"
     CDS             1329..2264
                     /locus_tag="VQ548_000914"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HET2653786.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            2276..2662
                     /gene="rplQ"
                     /locus_tag="VQ548_000915"
     CDS             2276..2662
                     /gene="rplQ"
                     /locus_tag="VQ548_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HET2653787.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            2927..3193
                     /locus_tag="VQ548_000916"
     CDS             2927..3193
                     /locus_tag="VQ548_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HET2653788.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            3203..4540
                     /locus_tag="VQ548_000917"
     CDS             3203..4540
                     /locus_tag="VQ548_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HET2653789.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     IGDSVARVLEEMGLETVGTHGTTVALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            4784..5476
                     /locus_tag="VQ548_000918"
     CDS             4784..5476
                     /locus_tag="VQ548_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2653790.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGCEKMEEGSI"
     gene            complement(5579..7224)
                     /locus_tag="VQ548_000919"
                     /pseudo
     CDS             complement(5579..7224)
                     /locus_tag="VQ548_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(7214..7519)
                     /locus_tag="VQ548_000920"
                     /pseudo
     CDS             complement(7214..7519)
                     /locus_tag="VQ548_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809465.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TOBE domain-containing protein"
     gene            complement(7646..8305)
                     /locus_tag="VQ548_000921"
     CDS             complement(7646..8305)
                     /locus_tag="VQ548_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2653791.1"
                     /translation="MSEIEIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIEGGEFYFDDTKINNMEPSKRNIGMVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYADRKPDKLSGGQQQRVTLACALAVNPSVLLMDEP
                     LSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     K"
     gene            complement(8318..9439)
                     /locus_tag="VQ548_000922"
                     /pseudo
     CDS             complement(8318..9439)
                     /locus_tag="VQ548_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(10027..10803)
                     /locus_tag="VQ548_000923"
     CDS             complement(10027..10803)
                     /locus_tag="VQ548_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HET2653792.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            10925..11671
                     /locus_tag="VQ548_000924"
     CDS             10925..11671
                     /locus_tag="VQ548_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2653793.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            11684..12664
                     /locus_tag="VQ548_000925"
     CDS             11684..12664
                     /locus_tag="VQ548_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HET2653794.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            12859..13179
                     /locus_tag="VQ548_000926"
     CDS             12859..13179
                     /locus_tag="VQ548_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2653795.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            13225..13533
                     /locus_tag="VQ548_000927"
     CDS             13225..13533
                     /locus_tag="VQ548_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2653796.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            13550..14848
                     /locus_tag="VQ548_000928"
     CDS             13550..14848
                     /locus_tag="VQ548_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2653797.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQTLGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKVQDRLAYQNEIKQS"
     gene            14999..17437
                     /locus_tag="VQ548_000929"
     CDS             14999..17437
                     /locus_tag="VQ548_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HET2653798.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            17456..18124
                     /locus_tag="VQ548_000930"
     CDS             17456..18124
                     /locus_tag="VQ548_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HET2653799.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            18142..19230
                     /locus_tag="VQ548_000931"
     CDS             18142..19230
                     /locus_tag="VQ548_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HET2653800.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            19685..22186
                     /locus_tag="VQ548_000932"
     CDS             19685..22186
                     /locus_tag="VQ548_000932"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HET2653801.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIRSKEIVAENNGALD
                     KVYNETVKAVTEQIDSLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAATGESISYVTWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            22380..23075
                     /locus_tag="VQ548_000933"
     CDS             22380..23075
                     /locus_tag="VQ548_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2653802.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            23087..23503
                     /locus_tag="VQ548_000934"
     CDS             23087..23503
                     /locus_tag="VQ548_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2653803.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(24130..24222)
                     /locus_tag="VQ548_000935"
     CDS             complement(24130..24222)
                     /locus_tag="VQ548_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HET2653804.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            24383..25354
                     /gene="ruvB"
                     /locus_tag="VQ548_000936"
     CDS             24383..25354
                     /gene="ruvB"
                     /locus_tag="VQ548_000936"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HET2653805.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            25335..25907
                     /locus_tag="VQ548_000937"
     CDS             25335..25907
                     /locus_tag="VQ548_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HET2653806.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            26138..26896
                     /locus_tag="VQ548_000938"
     CDS             26138..26896
                     /locus_tag="VQ548_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HET2653807.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            26905..27708
                     /locus_tag="VQ548_000939"
     CDS             26905..27708
                     /locus_tag="VQ548_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HET2653808.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            27730..28989
                     /gene="rseP"
                     /locus_tag="VQ548_000940"
     CDS             27730..28989
                     /gene="rseP"
                     /locus_tag="VQ548_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HET2653809.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            29002..30855
                     /locus_tag="VQ548_000941"
     CDS             29002..30855
                     /locus_tag="VQ548_000941"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HET2653810.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            30955..32334
                     /gene="bglA"
                     /locus_tag="VQ548_000942"
     CDS             30955..32334
                     /gene="bglA"
                     /locus_tag="VQ548_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET2653811.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIHDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KKLSDNNGF"
     gene            32526..34334
                     /gene="glmS"
                     /locus_tag="VQ548_000943"
     CDS             32526..34334
                     /gene="glmS"
                     /locus_tag="VQ548_000943"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HET2653812.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
BASE COUNT        10494 a         5881 c         7579 g        10512 t
ORIGIN      
        1 aaaaagtatt gacaaatttg aaataaagcg tttttcgcac ttgcaaaaat ccgctacaaa
       61 tgttatactg agatagtctg acttataatt gttgtctctg tgtctagagg catcgaatcg
      121 aaatttatgg aggtgctttt gcgtggcaaa agacgatgtg attgaagttg aaggcaaagt
      181 agttgataca atgccgaatg caatgtttac ggttgaactt gaaaatggac atcagatttt
      241 agcaacagtt tctggtaaaa ttcgtaaaaa ctatattcgt attttagcgg gagatcgtgt
      301 tactgtcgaa atgagtccat atgacttgac acgtggacgt atcacttacc gctttaaata
      361 atcgaaaaac ttggagggat aagaaatgaa agtaagacca tcggtcaaac caatttgcga
      421 atactgtaaa gttattcgtc gtaatggtcg tgttatggta atttgcccag caaatccaaa
      481 acacaaacaa cgtcaaggat aagatagaaa ggagaaaaca tggctcgtat tgctggagtt
      541 gatattccaa atgacaaacg cgtagtaatc tcattgactt atgtttatgg tatcggactt
      601 gcaacatcta agaaaatttt ggctgctgct ggaatctcag aagatgttcg tgtacgtgat
      661 cttacatcag atcaagaaga tgctatccgt cgtgaagtgg atgcaatcaa agttgaaggt
      721 gaccttcgtc gtgaagtaaa cttgaacatc aaacgtttga tggaaatcgg ttcataccgt
      781 ggtatccgtc accgtcgtgg acttcctgtc cgtggacaaa atactaaaaa caacgctcgc
      841 actcgtaaag gtaaagctgt tgcgattgct ggtaagaaaa aataatatag gaggtaaaag
      901 tcttggctaa accaacacgt aaacgtcgtg tgaaaaagaa tatcgaatct ggtattgctc
      961 atattcacgc tacatttaat aacactattg ttatgattac tgatgtgcat ggtaatgcaa
     1021 ttgcttggtc atcagctggt gctcttggtt tcaaaggttc tcgtaaatct acaccattcg
     1081 ctgctcaaat ggcttctgaa gctgctgcta aatctgcaca agaacacggt cttaaatcag
     1141 ttgaagttac tgtaaaaggt ccaggttctg gtcgtgagtc agctattcgt gcgcttgctg
     1201 ccgctggtct tgaagtaaca gcaattcgtg atgtgactcc agtgccacac aatggtgctc
     1261 gtcctccaaa acgtcgccgt gtataatcat cgcattacac tgcttttcgt ttaagaggga
     1321 gtaactaaat gatcgagttt gaaaaaccaa atataacaaa aattgatgaa aataaagatt
     1381 atggcaagtt tgtaatcgaa ccacttgaac gtggctacgg tacaactctt ggtaactctc
     1441 ttcgtcgtgt acttctagct tctctaccag gagcagctgt gacatctatc aacattgatg
     1501 gtgtgttaca tgagtttgac acagttccag gtgttcgtga agacgtgatg caaatcattc
     1561 tgaacattaa aggaattgca gtgaaatcgt acgttgaaga cgaaaaaatc atcgaactgg
     1621 atgttgaagg tcctgctgaa gtaacagctg gtgacatttt gacagatagc gatattgaaa
     1681 ttgtaaatcc agatcattat ctctttacaa ttggtgaagg ttcttctcta aaagcgacta
     1741 tgactgttaa cagtggtcgt ggatatgtac ctgctgatga aaataaaaag gataatgcac
     1801 cagttggaac acttgctgta gattctattt atacaccagt tacaaaagtc aactatcaag
     1861 tggaacctgc tcgtgtaggt agcaatgatg gtttcgacaa attaaccctt gaaatcttga
     1921 caaatggaac aattattcca gaagatgctt tagggctttc agcacgtatt ttgacagaac
     1981 atcttgattt gtttacaaat cttactgaga ttgctaagtc aactgaagtg atgaaagaag
     2041 ctgatactga atctgacgac cgtattttag atcgtacgat tgaggaactg gacttgtctg
     2101 tgcgttcata caactgttta aaacgtgccg gtatcaatac tgtgcatgat ttgacagaaa
     2161 aatctgaagc agagatgatg aaagtacgaa atcttggacg caagagtttg gaagaagtga
     2221 aactcaaact cattgatttg ggtcttggat taaaagataa ataaaggagg aatacatggc
     2281 ttaccgtaaa ctaggacgca ctagctcaca acgtaaagca atgcttcgcg atttgacaac
     2341 tgaccttttg atcaacgaat caatcgtgac aactgaagct cgtgctaaag aaatccgtaa
     2401 aactgttgaa aaaatgatta ctctaggtaa acgtggtgat ttgcatgcac gtcgtcaagc
     2461 agctgctttc gtacgtaatg aaatcgcatc tgaaaactat gatgaagcaa ctgataagta
     2521 cacttctact acagcacttc aaaaattgtt ctcagaaatc gcacctcgtt atgctgaacg
     2581 taacggtgga tacactcgta tccttaaaac tgaaccacgt cgtggtgatg cagcgccaat
     2641 ggcgatcatc gaattagtat aaaatcatca attttgttga gtgttatgat gatggagtct
     2701 tgtgctctta gtctagctct ggtctaccgc taggatttcg gtcctagcgg gaacactcat
     2761 cataagttgg gatagtagac gcttgtttac gaaattgttt ttttcttaag aacaacttcg
     2821 taagcaggcg tttttgagta ttttcgttag aattatgcta tactatttga aaagaatcct
     2881 gtttaatgtt aaggtttctt attttaagaa gaattggagt ttacttatga aagccattat
     2941 aactgttgtt ggtaaagata aatctggaat tgttgcaggt gtttctggta aaattgcaga
     3001 attaggattg aatattgacg atatctctca aactgtcttg gatgaatatt ttacgatgat
     3061 ggctgttgta tctagtgatg aaaagcaaga ttttacctat cttcgtaatg aatttgaagc
     3121 ttttgggcaa actttgaatg taaaaatcaa tattcagagt gcagcgattt tcgaagctat
     3181 gtataatatc taggaggtca tcatggatat tagacaagtt actgaaacca tcgccatgat
     3241 tgaggagcaa aacttcgata ttagaaccat taccatgggg atttctcttt tggactgtat
     3301 cgatccagat atcaatcgtg ctgcggagaa aatctatcaa aaaattacga caaaggcggc
     3361 taatttagta gctgttggtg atgaaattgc ggctgagttg ggaattccta tcgttaataa
     3421 gcgtgtatcg gtgacaccta tttctctgat tggggcagcg acagatgcga cggactacgt
     3481 ggttctggca aaagcgcttg ataaggctgc gaaagagatt ggtgtggact ttattggtgg
     3541 tttttctgcc ttagtacaaa aaggttatca aaagggagat gagattctca tcaattccat
     3601 tcctcgcgct ttgactgaga cggataaggt ctgctcgtca gtcaatatcg gctcaaccaa
     3661 gtctggtatt aatatgacgg ctgtggcaga tatgggacga attatcaagg aaacggcaaa
     3721 tctttcagat atgggagcgg ctaagttggt tgtattcgct aatgctgttg aggacaatcc
     3781 atttatggcg ggtgcctttc atggtgttgg ggaagcagat gttatcatca atgtcggagt
     3841 ttctggtcct ggtgtggtga aacgtgcttt ggaaaaagtt cgtggacaga gctttgatgt
     3901 agtagccgaa acagttaaga aaactgcctt taaaatcact cgtatcggtc aattggttgg
     3961 tcaaatggcc agtgagagac tgggtgtgga gtttggtatt gtggacttga gtttggcacc
     4021 aacccctgcg attggagact ctgtggcacg tgtccttgag gaaatggggc tagaaacagt
     4081 tggcacgcat ggaacgacgg ttgccttggc cctcttgaac gaccaagtta aaaagggtgg
     4141 agtgatggcc tgcaaccaag tcggtggttt atctggcgcc tttatccctg tttctgagga
     4201 tgaaggaatg attgctgcag tgcaaaatgg ctctcttaat ttagaaaaac tagaagctat
     4261 gacggctatc tgttctgttg gattggatat gattgccatc ccagaagata cgcctgctga
     4321 aaccattgcg gctatgattg cggatgaagc agcaatcggt gttatcaaca tgaaaacaac
     4381 agctgttcgt atcattccca aaggaagaga aggcgatatg attgagtttg gtggtctatt
     4441 aggaactgca cctgttatga aggttaatgg ggcttcgtct gtcgacttca tctctcgcgg
     4501 tggacaaatc ccagcaccaa ttcatagttt taaaaattaa gaaaatagga gaaattttaa
     4561 gttctattta agattagatg tgtatactat aatcattaaa taaagacctc ctaatattat
     4621 ttgaaacaga taacactgaa ttagtttgaa tttgattttc atctaatatc tttatttaat
     4681 gaactcctaa actttttcat aataatctcc ttcaaaagtc gcctgtatgg gtggctttta
     4741 ttttatcatt catgatataa tagaagcaaa cggaggacgg aaaatggtaa aagtacgatt
     4801 gtatttggta cgtcatggca agaccatgtt taacacgatt ggtcgcgcgc aaggttggag
     4861 cgatactccc ttaactgctg aaggtgaacg agggattcaa gagttaggaa tcggtttgcg
     4921 agaatctgat ctacagtttg agcgcgctta ttcgagtgat tctggtcgta ccattcagac
     4981 catgggaatt atccttgaag aacttggctt gcaggggaaa atcccttatc gcatggacaa
     5041 gcgtatcaga gaatggtgtt tcggtagttt tgatggagcc tatgatggcg atcttttcat
     5101 gggcattatt cctcgtatct ttaatgtgga ccacgttcac caattgtctt atgctgaact
     5161 ggctgagggc ttggtagagg tcgatacagc tggttgggct gaaggctggg aaaaactcag
     5221 tggccgaatc aaggaaggct ttgaaatgat tgcaaaagaa atggaagatc aaggtggagg
     5281 taacgccctt gttgtcagcc atggaatgac tattggaacc attgtttatc tgattaatgg
     5341 catgcatccg catggtctag ataatggtag cgtgacgatt cttgaatatg aggacggtca
     5401 gtttagggtt gaagttgtcg gtgaccgtag ttaccgagag ctaggatgtg agaagatgga
     5461 agaaggctct atttaatcag tctagacttg cttgccatga gctagggatt tgataagaat
     5521 atcaagataa gaaaaaacag ccgagggcac tcctttcggc tgtttttgat gtggaaaact
     5581 aaagtgtaat gctattgctt ttagagattt tcataaacaa gagcaaggaa cctactgtta
     5641 gaacagtcag gatagttgac aaggctgcgg ctacaccgta atttcctctg agaacctctg
     5701 tataaatagc tacagtcatt gttcttgttt tgacattgta gaggaggata gaagtagaga
     5761 gttttgaaat cattgtgacc caagataaga tggctccaga aatgatacca gatagcatca
     5821 ttggagttgt aatcttagca aaggtattga gacgactact tcctaagctt tcagcagctt
     5881 cttcaatact tggtgctatt tgttgtaagc tagcaacaga tgagcgaata gtataaggta
     5941 atcttctgac agatagagac ataatcaaga tgaaagcagt ccctgtaatc ataagaaatc
     6001 cacttccaaa tagaccagta ttgaaggaag aaatgaaggc aatccctaga acggttcctg
     6061 gtacaatata aggtaccata ctgaggctgt caattaagtt tgtaaacaaa ttccgttttc
     6121 taacggctag gtaggagata aatgtcgcaa atagaacaac tagaactaag gcaatcaaag
     6181 ggatacgaat ggtattgaaa atagcagatc ccatacgatt gaaagctacc ttgtaactgt
     6241 ttggagaata acctttaaca gataccatac ctgatgtttt taggaaagag gtataaatta
     6301 agtagatttg aggtaaaaca gagataaaga taattccgta gactgttgca taaatggcag
     6361 ctatttttcc ttttgtagtt tttttaggct caattggatg gagcagattc atgctgaaac
     6421 tgtagcggtt tgcaatgtgt ttttggataa ggaaaattgc caaggcaatg ataatcgcca
     6481 taattgcaaa agcagaattt cctccaacct cgctaataaa ttgggtataa atcaggacag
     6541 ggaaagtccg atatccttcg tcaatcaaca taggcgttcc aaagtctgag aatgctctca
     6601 taaatacaag caaggagctg ctagtaaggt tggaactagg agaggtaaaa caaccgttac
     6661 gatacgctta aatccgaagg accccatgct ttcagctgct tcaagtagag aattgtcaat
     6721 actgttcatt gttccagcaa catatagaaa taccagtggg aatagttgca gtgtaaagac
     6781 aagtacaatt cctttgaatc cataaatatc gatagctgga agatgaaggg catttgtcaa
     6841 aaatttagtg atgacctcat ttcgtcccag caagagaatt caggagtagg ctcctacgaa
     6901 aggagctgac atggaagcaa tgataatcaa tatttgtaga aatttcttcc ccttgaagtc
     6961 atacatagag aagagataag ctaatagggt tcctacaact aaggaagtga tagtagcggt
     7021 aatggaaacc ttgaaactgt tgactagtgt ctcagagtag taggctttac taaagaaagt
     7081 gacaaaatta gctagtgaga attgtccttc atgtataagt gcttgcttga gcacggtaac
     7141 gataggataa acgagaaaga caagataggt aagaaagatg aagaaagagg aagctgtcca
     7201 aatatttagt tttttacatt ccatggttga ctccttttat caggttttgg gaaccatctg
     7261 cagaaaagat gtttaatttt tgcgtattga ttcgtagacg aatacgattg cctttttgta
     7321 gttcttcttc aaaagttgat tcttcactaa cttaaatttt tgaggcaaaa cctgtctcaa
     7381 tgaaatactc cgtatttagt ccaagataga cgctatcgct aatagttcct tcgatatctc
     7441 cagattcatc tttgataaac tcttcgggac gaatgcttac atgaatagct tgctcctcaa
     7501 cctgatcaag agctggcatt cgaagggcat agccatctga aaagacgata taagcgccgt
     7561 cgctccgttt ttcaagattg gcagggataa tatttgtgcg tccgataaag gttgccacaa
     7621 actcattagc tggtttatga tagagttatt ttggtcggcc gatttgttgg atcaccccat
     7681 ctttcataac agcaatttgg tctgaaatag ccatggcttc ttcttggtcg tgggttacat
     7741 aaacagttgt aattcccact tcgtgttgga tttctcggat ggcttgacgc atatccaagc
     7801 gaagtttggc ctccagatta ctaagtggct cgtccatgag gagaacactt ggattaaccg
     7861 ctaaggcgca tgccaaggtg acacgttgtt gttgtccacc actgagttta tcgggctttc
     7921 gatccgcata ttgagcaatt tgcatgagtt caagatactt gttggtctgt tgaatcaatt
     7981 cttcttttgg aaccttcttt tgcataagac caaaagcaac gttgtctcgg acagtcaaat
     8041 gtgggaaaat agcgtagttt tggaaaacca tcccgatatt gcgtttgctg ggttccatat
     8101 tattgatttt tgtatcatcg aagtaaaatt ctccaccttc gatactgttg aaacctgcaa
     8161 tcatacgaag aagggtcgtt ttcccacatc ctgaagctcc aagaagggta aagagacttc
     8221 cttttggaat tgtaatgttc aaattctcaa taacagggac atcgtggtag atttttttgg
     8281 cgttaataat ttcgatctca ctcatagtga acctctttta ctgtttagat tggatatctg
     8341 taaagacttc gttgtatttc ttaacgatat ctgatttatt cttgatgaca taatcataat
     8401 cttcagtgag tgttttgatt ttgtcaattg gtttcatgtt ttcgcttgtt ttagcatttt
     8461 tacgaacagg acggttagta gtggttgtac caagtgtatc ttgtacttct tgagagataa
     8521 taaaatcgat aaatttcttg gcattttcca tatttttaga ttttttaacg atagcagcac
     8581 tagcaggtag gaagacggtt ccttcttttg gatagactac cttaatgtta gctccgtcat
     8641 ttaagagttt aactgctgga tcttcataag agagactaac agtcatttct ccatcagcga
     8701 ctgctttata gacaccagat gaacttaaac cgattttata gtatattgaa actagaatag
     8761 tacacatcta cttctaaaac attgttagaa atcgatttga ctgtcctgat taatttgtcc
     8821 tgttcttatt tcattttact ataccatcaa taagtgtgaa aagatctttt acataagacc
     8881 aagccttatc atctttgtaa ccaccttgag cttgtagcat atttgttaat tgagcaaagg
     8941 cgctagaaga gtttgctggg tcagcagttg cgatttttcc ttttagttca ggtttgagaa
     9001 ggtcgctata tccttcgatg ttcatgcctt tagttaaatc agggtggacg attaaaacac
     9061 taccatctag tgtataagga gtagagaagc cagttgtgtt ttgatattct ttgataacat
     9121 tatcattttc ttttgaaata tagttttcaa agagttctcc gtgggtagca tattgtgtat
     9181 aagaaccacc aaagataata tcagctacag gaacttcttt ttctgactct agttttttga
     9241 aaagttctcc agtaccagct tgaatcagtt ctattttgat accatatttt tcttcaaagg
     9301 caggaatagt tgctccaatt aagccttctg agtttggtga ataaacgact agcgaaccac
     9361 cgtctccttt atcagatgaa ctgtcatcgg cagattcatt agaagaacaa gcagcataat
     9421 acatccattt ctttttcatg atggatacct ccgttgtgtt atttaagttt attttaaaac
     9481 aatgtaagcg tttttaaaac ctacaattct attctatagt gtattgaatc tataacagta
     9541 cacattgact gctaaaatat ttctataaat taatttgact ttcctgatag agatgttcac
     9601 atcttatttc aattcactat attagagtaa aattctctac aaaaaaaaag aatagcctat
     9661 tttactattt ttccgagtga tttcaattcc tttggggaaa tatggagata ctttttaaat
     9721 cctgacaaat ggttgtttct ttttctaaat cggtgatact gtatcggaga atgcgcgtga
     9781 ggtcacaaag gctgcgatag agcttctatg gagaatttct ttttggagag attttttaaa
     9841 ggaatgagac atccgctacc tccttggaag gtttttttgt gataagtata gcagtttaaa
     9901 aattctagag caaggtaaaa tagaaaaggt ttggctaaaa ttttttagct aaaccttttg
     9961 aaaagttaag tatgtattat agatgcttgt tatctgcaaa tagctagagc atttcaagga
    10021 aataaactag aaataacaat taatatggtg gttcagaaat accttttgat aatcaataag
    10081 atcttcagga tgaagtgcgt tgattccatc catttcatat ttccgattta ataaacgata
    10141 tttgttttca ccaaattgat gaaaagggag tagttgaact tggtcgatat ttaatgagtt
    10201 aaatagagta gcgaattttt ctgcatcctc taaactattg ttaaaattag gaataactgg
    10261 gattcttaaa acgatagttt tattttgtga aaaagcataa tgaatgtttt taataatcat
    10321 ttgattaaaa accccagtca cttttttatg ttttatagaa ttataatgtt ttaggtctgt
    10381 gtagataaaa tccacatatt gaattaaatc aataaatttt tcatgatcaa caaaggcagt
    10441 agtttcaatg gcagtgtgta tgtgatgttc tttagctgat tttaagatag ctttagcaaa
    10501 ttcaaactga gcaaatattt cacctcctga taaagttaaa cctccaccgg attcttcgta
    10561 aaattctttg tcttttaata cctctgtaat aatttcttct acagtctttt cttcaccgac
    10621 taaggtgaat ttctctcgtt gagcatcttt cattttttca ggtttcattc tttgagattc
    10681 aggattagaa caccatggac agcgcagagg acatcctttt aaaaaaacag ttgtacgaat
    10741 acccgggccg tcatgaattg aaaagtgttg aatattaaaa ataattcctt tagatatttc
    10801 cataagagtt cctcctcttc ataagtctat cctatcacaa aaacgaaaga aaaacaatta
    10861 cgaacgaaag gttaatttgt tgttttttgc tttttatttt ggtagaataa aacggaggtg
    10921 taaaatgaaa agattggaac aaattattaa attagtatca gaatatgaaa agatcgacgt
    10981 taatacatta tcggaaaaat taaatgtatc gaaagtaacg attagaaaag atttagataa
    11041 attagagtca aaaggtttat tacacagaga gcatggatat gctgtattaa atagtggaga
    11101 tgacttaaat gtacgtttgt caattaatta tgaaattaag agaaaaattg ttcaggaagc
    11161 agtaaaattg gtgtcagata atgaaacgat aatgatagaa tctggatcga cctgtgcttt
    11221 acttgctgag gaaatttgca agcaaaaaag aaatgttacg attgtaacaa attcattttt
    11281 tatagcaaat tttgtgagag cttatgattc atgtcgtatt attgttcttg gtggagagtt
    11341 tcagaaggat tcacaggtta ctgtgggacc tttattaaaa gaaatgatac agacttttca
    11401 tgtgcatcaa gcttttgttg ggacagatgg atacgataaa gagatgggct ttacaggaaa
    11461 agatttaatg cgcagtgagg tagttcaata tatttcagca gcgtcggata aagtcattgt
    11521 cctaactgac tcaagtaaat ttgataaaag gggtacagta agaagatttg ctttaagtca
    11581 agtctatgaa gtaataacag acgaaaaact ttctaaacaa aatatagcta cattagaaaa
    11641 tgctgggata atggttaagg tagtttcgta agaggttaag tgtatgaatc aagataggaa
    11701 taaactgctc tctaaaattg cttatctgta ttatattgaa aacttaaatc agtcacaaat
    11761 agcagcaaaa ttaggaattt atagaacctc tattagtaga atgttaacag aagcaaggaa
    11821 tgcaggaatt gttaaaattg aaatagagaa ttttgatacc aatatgttta agttggaaaa
    11881 ttatgtaaaa gaaaaatatg gtctggaaag tttagaaatt attccaaatg aatttgatga
    11941 taatccaaca attttatctg aaagaatttc tcaagttgca gcaggtgtcc ttaggaatct
    12001 aattgatgat aatatgaaaa ttggcttttc ttgggggaaa agtttaagta atttagtaga
    12061 tttaattcac agtaaaagtg tccgaaatgt tcacttctat cctctagcag gtggtcctag
    12121 tcacatacac gctaaatacc atgtgaatac actgatttat gaaatgtcta gaaaatttca
    12181 tggagagtgt acatttatga atgcaacgat tgtgcaagaa aataaattgt tagcagatgg
    12241 tattttgcaa tcaagatatt ttgaaaattt gaaaaatagt tggaaagatt tagatatagc
    12301 tgtagtcgga attggtgatt ttagcaataa aggaaagcat caatggttag acatgcttac
    12361 agaggatgac tttaaagaat tgaccaaagt taaaactgta ggagaaattt gttgtcgatt
    12421 ttttgattca aaaggtaaag aagtctatga aaacttacag gaaagaacga tagcaatctc
    12481 tttggaagat ttaaaaaata ttcctcaaag tttagctgtt gcttacggtg atacgaaagt
    12541 atcttcgatt ctttctgtct tgcgtgctaa tttagtaaat catttgatta cagacaaaaa
    12601 tacaatttta aaagttttgg aagaagatgg ggatttgact tttagagaga ttctaggtga
    12661 gtgaaaatga tagactgatt cagtttatcg tttttctttt tagttgattg cacatttgtg
    12721 cttatataaa caaaaatagt ttatctgttg tttttggatt gacaacttta ttatgtagtt
    12781 gtattctata gttacaaaag aaaattttaa aatttcaaat gaaaaaagct ttttacatag
    12841 tgaaatgagg aggaatttat ggaaattatt gttccagatc aaattatcat gggtttaatt
    12901 ttatatgctg gtgatgcgaa acaacatatt tataaagcgt tagattacat aaaaaatggt
    12961 acatgtgaac ggtgtgaaga agaaatccag ttagctgatg ccgccttatt agaagcccat
    13021 aatctacaaa caaaattctt ggcacaagaa gcgtctggta caaagacaga aattacagct
    13081 ctctttgttc attcacaaga tcatctcatg actagtatga cggagattaa tttaatcaaa
    13141 gaaattatta gtttgagaaa agaacttcat aaaaaataat actagagtat tatcattgtt
    13201 attaacatag aggaggaaaa cataatggtg aagattggtt tgttttgtgc agcaggtttt
    13261 tctactggta tgcttgtaaa taatatgaaa attgcagcgc aatctagtgg agttgaggca
    13321 gaaatagagg cgttttctca gtctaaatta gcggattatg cgccaaatat agatgttgca
    13381 ctattgggtc cacaagttgc ttatacatta gataaatcaa aagaaatttg tgataagtgt
    13441 gatgttccga tagctgttat tccgatgatg gactatggta tgttagatgg gaaaaaagta
    13501 ttagatttgg ccctatcttt gattagtggg taagaaaagg agatttatta tgtcaaagat
    13561 ggatgttcag aaaatcattg caccgatgat gaagtttgtg aatatgcgtg gcattatagc
    13621 tctaaaagat gggatgttag caattttgcc attgacagta gttggtagtt tgttcttgat
    13681 tatgggacaa ttgccgttcg aaggattaaa taagagcatt gctagtgttt ttggagctaa
    13741 ttggacagag ccgtttatgc aagtatattc aggaactttt gctattatgg gtctaatttc
    13801 ttgtttttca attgcctatt cttatgctaa gaatagcgga gtagaggctt taccagctgg
    13861 agttctatct gtatctgcat tctttatttt gctaagatca tcttatatcc ctaaacaagg
    13921 tgaggcgatt ggggacgcta ttagtaaagt ttggtttgga ggccaaggaa ttatcggtgc
    13981 tatcattata ggtttggtag taggaagtat ttataccttc tttataaaga gaaaaattgt
    14041 tattaagatg ccagaacaag ttccacaagc tattgccaaa cagtttgaag caatgattcc
    14101 agcatttgta attttcttat cttctatgat tgtatatatt ttagcgaagt cattgactaa
    14161 tggcggaaca ttcatagaaa tgatttattc tgctattcaa gttccgttgc aaggtttaac
    14221 tggatctttg tatggtgcta ttggaattgc attctttata tcatttttgt ggtggtttgg
    14281 tgttcatggg caatcggtag taaatggagt agtgacagct ctgcttttat ctaatcttga
    14341 cgctaataaa gctatgttag cctctgctaa tctatcatta gaaaatggtg cacatattgt
    14401 tactcaacaa tttttagatt catttttaat tctatcaggt tcagggatta cgtttggtct
    14461 tgtagttgcc atgctttttg cagcaaaatc aaaacaatac caaaccttag gaaaagttgc
    14521 agcttttcca gcaatattta acgtaaatga gccagttgta tttggatttc cgattgtcat
    14581 gaatccagtt atgtttgtac ctttcattct tgttcctgta cttgcagctg tgatagtata
    14641 tggagctatt gcaacaggtt tcatgcagcc attctcaggg gtaacattgc cttggagtac
    14701 accagctatt ttatcaggat ttttggtggg tggatggcaa ggagttatta ctcagctggt
    14761 gatattagcg atgtctacat tggtttattt tccattcttt aaagtacagg atcgtttagc
    14821 ttaccaaaat gaaatcaaac aatcttagag gtatttgtgt gttactgtta aactcacaca
    14881 tttgtgctaa aaattagaga gttaaaattt ttctagttaa aagcttgaaa atttctataa
    14941 aaatcggtat tatattttcg aaagaaataa aaatattttc gaaagaaagg tggttacgat
    15001 ggtaaataca gaagtagcaa gaacaacaat caagacagaa tattttggca gccttactga
    15061 aaggatgaac aaatatcgag aagatgtttt aaataaaaaa ccttatattg atgctgagag
    15121 agcagttcta gcaacacgcg cctatgaacg atacaaggaa caacctaatg tcctaaaacg
    15181 tgcatatatg ctgaaagaaa ttttggaaaa tatgactatc tatattgaag aagaatctat
    15241 gattgcggga aatcaagctt cttccaataa agatgctcct atttttccgg aatatacgct
    15301 agaatttgtt ctcaatgagt tggatctttt tgaaaagcgt gatggagatg ttttctatat
    15361 tacagaagaa acaaaagaac aacttagaag tattgctccg ttttgggaaa ataataattt
    15421 acgtgctaga gctggtgcct tattacctga agaagtgtct gtttatatgg aaacaggatt
    15481 cttcggtatg gaaggtaaga tgaattctgg agatgctcac ctagcagtta actatcagaa
    15541 acttttgcaa tttggtttaa gaggttttga agagcgggct cgtaaagcaa aagtagctct
    15601 agatttaaca gatccagcaa gtattgataa atatcatttt tacgactcta tatttatcgt
    15661 aatcgatgct attaaagtat atgcaaagcg ctttgttgct cttgctaaaa gtttagccga
    15721 aaatgcaaat cctaaacgta agaaagaatt acttgagatt gcagatattt gctctagagt
    15781 cccatatgaa ccggcaacta cttttgcaga agctattcaa tcagtttggt ttattcaatg
    15841 tattttacaa attgaatcta atggccactc tctttcatat ggccgttttg atcaatatat
    15901 gtatccatat atgaaggctg atttagaaag tggtaaagaa acagaagata gcattgttga
    15961 acgtctgaca aatctttgga ttaagacaat tacaatcaat aaggttcgca gtcaatcaca
    16021 tacattttct tcagcaggaa gtcctttata tcaaaatgtt acaattggtg gacagactcg
    16081 agataagaag gatgctgtta acccattatc ttatttggta ttaaaatcag ttgcacaaac
    16141 ccatctaccg caacctaatc taactgtacg ttaccatgca ggtttagatg ctcgtttcat
    16201 gaatgagtgt attgaagtga tgaaacttgg ttttggtatg cctgcattta ataatgatga
    16261 gattattatt ccttctttta ttgcaaaagg agtattggaa gatgatgctt atgattacag
    16321 tgccattgga tgtgttgaaa cggcagttcc agggaaatgg ggctatcgtt gcacaggtat
    16381 gagttatatg aacttcccta aggttctact tatcacgatg aatgatggaa ttgatccggc
    16441 ttcgggtaaa cggtttgcac caagctttgg tcattttaag gatatgaaga acttttctga
    16501 attagaaaat gcttgggata aaacactaag atatttgaca cgaatgagtg ttattgttga
    16561 aaattctatt gatttatcat tggaacgaga agttcctgat attctatgtt cagcattgac
    16621 tgatgattgt attggtcgtg gaaaacacct taaagaaggt ggagcagtat atgattatat
    16681 atcaggattg caagttggaa ttgcaaattt gtcggattca ttagctgcaa ttaaaaaatt
    16741 ggtgtttgag gaagaacgta taagcccaag tcagctttgg catgcactgg aaacagatta
    16801 tgccggagaa gaaggtaagg tcattcaaga aatgttgatt catgatgcac ctaagtatgg
    16861 taatgatgat gattatgctg acaaattggt tactgctgct tatgacattt atgttgatga
    16921 aattgctaaa tatcctaata cacgttatgg aagagggcct attggaggaa ttcgttattc
    16981 aggaacatct tctatctcag ccaacgtagg gcagggacgt ggaacattag caactccaga
    17041 tggacgcaac gcgggtacac cgttagcaga gggttgttca ccatcacata atatggatca
    17101 acacggccct acatctgttt taaaatctgt ttcaaaatta ccaacagatg aaatcgtagg
    17161 tggggttctc ttaaatcaga aagtaaatcc tcaaacgtta gccaaagaag aagataaatt
    17221 aaaactaatt gctttgttac gaacattctt taatcgttta catgggtacc atattcaata
    17281 caatgttgtt tccagagaga cgttgattga cgctcagaaa catcctgaaa aacacagaga
    17341 cttaattgtt cgtgttgcag gatactctgc attcttcaat gttctttcta aggcaaccca
    17401 agatgacatt ataggacgta ctgagcatac tttgtaaaat aaagaggttc tttttatgga
    17461 atttatgctt gacacattaa atttagatga gattaaaaag tggtctgaaa ttttgccgct
    17521 agctggggta acttcaaatc ccactattgc aaaaagagag ggttctatta atttttttga
    17581 acgaatcaaa gatgtaagag aattgattgg ctctacaccc tctattcatg ttcaggtgat
    17641 ttctcaagat tttgaaggca tcttaaagga tgctcatgaa attcgaagac aagcaggaga
    17701 tgatatattt atcaaagtac ctgttactcc agctggatta cgtgcaataa aggtgctaaa
    17761 aaaagagggc taccatatca ctgcaacagc tatttataca gttattcagg gattattagc
    17821 tatcgaagta ggagcggatt acctagctcc atattataat agaatggaaa atctgaacat
    17881 tgattcaaat tctgtcattc gtcaattagc tcttgctatt gatagacaga actctcctag
    17941 taagatttta gctgcatcct ttaaaaatgt agcacaagta aataatgctt tagctgcagg
    18001 tgcgcatgct gttacagcag gagcagatgt ttttgaatca gctttcgcca tgccatctat
    18061 ccaaaaggcg gttgatgatt tttctgacga ttggtttgtt actcaaaata gtcgttccat
    18121 ttagatagag aggaaataca tatgagaatt tttgctagtc cttctagata tattcagggg
    18181 gaaaatgcct tgtttgaaaa tgccaaatca attttggatt tgggaaatta ccctattcta
    18241 ttatgcgatc agttggttta tgatattgtt ggaaaacgat ttgaagatta tctacatagg
    18301 tatggtttcc atattgttct ggcgctattt aatggtgaag cttctgacaa tgaaatcaat
    18361 cgagttgttg ccttggctga gaaagaaaat tgtgatagta ttatcggtct tggtggggga
    18421 aagacgattg atagcgcaaa agctattgca gatttgattg aaaagcctgt tattattgct
    18481 ccaacaattg catcgaccga cgcacctgta tctgctttat ctgttattta tacagatgaa
    18541 ggtgcatttg atcattatct attttattct aaaaatccag atttagtttt ggttgataca
    18601 aaagttattt cacaagcccc taagcgttta ttagcgtctg gtattgcaga tggtttagca
    18661 acttgggttg aggcgcgtgc ggttatgcag gcaaatggaa aaactatgtt gggacaacag
    18721 caaacattgg ctggagttgc aattgcgaag aaatgtgaag aaacgctgtt tgcagatggt
    18781 ttacaggcta tggcagcttg tgaagctaaa gtggtgacac cagcattaga aaatattgtt
    18841 gaagctaata ctttattgag tggcctaggt tttgaaagtg gaggattagc tgcggcgcat
    18901 gcaattcata atggttttac tgcattgaca ggtgacattc atcatttaac acatggtgaa
    18961 aaagtagctt atggaacttt agtacaacta ttattggaaa atagacctaa agaagaactt
    19021 gataagtata ttgagtttta caaaaaaatt ggtatgccaa caactctaaa agaaatgcat
    19081 ttggatcaag ttggatatga tgatttaata aaagttggta aacaagcaac tatggagggt
    19141 gagacaattc atcagatgcc gtttaagatt tcgccttcag atgttgctca agctattatc
    19201 gctgtagatg cctatgtaaa ttcaaaataa acaataagga ctactgtttt ccaaatggta
    19261 gtcttttatt gatcctcgta ttgaattcta tagcagattg aaataagatg agaacaaatc
    19321 gattgggaaa gtaaaattaa tttctataag tattttagca attgtttcgt actatttcag
    19381 attcagtcca ctatacgttc ttcataaatc aaaaagcgac ataggttgtc ggctatttat
    19441 tgtgaataca ttaattagca ttccagtttt atcttcggtc taaaataagt attttgtgct
    19501 atacgagata agtttcttga cttactcctt gatttactgc ataacaatgg gataaaaagt
    19561 gggagataga gcaattcata gtcatcaaaa ttaatgagat acagtataca gtttttcctt
    19621 taaacacatt tcaaattccc tcaaaaatgg tataatagta acatcacaaa attggagaga
    19681 gaccatgagt ttttacaatc ataaagaaat tgagcctaag tggcagggct actgggcaga
    19741 acatcataca tttaagacag gaacagatgc atcaaaacct aagttttatg cgcttgatat
    19801 gttcccttat ccgtctggag ctggtctgca cgtaggacac ccagaaggtt atactgcaac
    19861 cgatatcctc agtcgttaca aacgtgcgca aggctacaat gtccttcacc caatgggttg
    19921 ggatgctttt ggtttgcctg cagagcaata cgctatggat actggtaatg acccagcaga
    19981 atttacagcg gaaaacattg ccaacttcaa acgtcaaatc aatgcgcttg gattttctta
    20041 tgactgggat cgtgaagtca acacaacaga tccaaactac tacaagtgga ctcaatggat
    20101 tttcaccaag ctttacgaaa aaggcttggc ctatgaagct gaagtgccag taaactgggt
    20161 tgaggaattg ggaactgcca ttgccaatga agaagtgctt cctgacggaa cttctgaacg
    20221 tggaggctat ccagttgtcc gcaaaccaat gcgccaatgg atgctcaaaa tcacggctta
    20281 cgcagagcgc ttgctcaatg acttagatga actagattgg tcagagtcta tcaaggatat
    20341 gcaacgcaac tggattggta aatcaactgg tgccaatgta actttcaaag taaaaggaac
    20401 agacaaggaa tttacagtct ttactactcg tccggacaca cttttcggtg cgactttcac
    20461 tgttttggct cctgaacatg aattagtaga tgccatcaca agcacagagc aagcagaagc
    20521 agtagcagac tacaaacacc aagccagcct taagtcagac ttggctcgta ccgaccttgc
    20581 caaagaaaaa actggtgtat ggactggtgc ttatgccatc aatcctgtca atggtaagga
    20641 aattccaatc tggattgcgg attacgttct tgctagctat ggtacaggtg cggtaatggc
    20701 tgtgcctgcc cacgatcaac gtgactggga atttgccaaa caatttgacc ttccaatcgt
    20761 cgaagtactt gaaggtggaa atgttgaaga agctgcctac acagaagatg gccttcacgt
    20821 taattcagac ttcctagatg gactcaacaa agaagacgct attgccaaga ttgtggcttg
    20881 gttggaagaa aaaggctgtg gacaagagaa ggtaacctac cgtctccgcg actggctctt
    20941 tagccgtcaa cgttactggg gtgagccaat cccaatcatt cattgggaag atggaacttc
    21001 aacagctgtc cctgaaagtg aattgccact tgttttgcct gtaaccaagg atatccgtcc
    21061 ctcaggtact ggtgaaagtc cactagctaa cttgacagac tggcttgaag tgactcgtga
    21121 agatggtgtc aaaggtcgtc gtgaaacaaa tactatgcca caatgggcag gttcaagctg
    21181 gtactacctc cgctatattg acccacacaa tactgagaaa ttggctgacg aggatctgct
    21241 caaacaatgg ttgccagtag atatctacgt gggtggtgcg gaacatgctg tacttcactt
    21301 gctttacgct cgtttctggc ataaattcct ctatgacctc ggtgttgttc caactaagga
    21361 accattccaa aaactcttta accaaggaat gattttggga acaagctatc gtgaccaccg
    21421 tggggctctt gtggcgactg acaaggttga aaaacgtgat ggttctttct tccatgtgga
    21481 aacaggggaa gagttggagc aagcgccagc caagatgtct aaatcgctca agaacgttgt
    21541 caacccagac gatgtggtgg aacaatacgg tgctgatacc cttcgtgtct atgaaatgtt
    21601 catgggacca ctcgatgctt cgattgcttg gtcagaagaa ggtctggaag gaagtcgtaa
    21661 gttccttgac cgtgtttacc gtttgattag aagtaaggaa attgttgcgg aaaacaatgg
    21721 cgctcttgac aaggtttaca acgaaactgt taaagctgtc acagagcaaa ttgattccct
    21781 caaattcaac acagccattg cccaacttat ggtctttgtc aatgcggcta acaaggaaga
    21841 caagctctat gttgactatg ccaaaggatt tatccaattg attgccccat ttgcacctca
    21901 cttggcagaa gaactctggc aaactgttgc tgcaacaggt gagtcaatct cttacgtgac
    21961 ttggccaaca tgggacgaaa gtaaactggt tgaagacgaa atcgaaatcg ttgtccaaat
    22021 caaaggtaaa gtccgtgcca aactcatggt cgctaaagac ctatcacgtg aagaattgca
    22081 agaaattgct ctagcggatg aaaaagtcaa agcagaaatt gacggtaagg aaatcgtgaa
    22141 agtgattagt gtaccaaata aattggttaa tattgttgta aaataaccaa tttatttgct
    22201 gatttccaac ctcaaacagt ttcccaaact gtttgagcca actaaactcg ttaatatcgt
    22261 tgtgaaataa ggtaggaatc cttcagagta gaatctggag gattttttga atcttcttat
    22321 gaaagtatgg tatactatgg gcaactataa agtttgaaaa gtgaaaaaag gagaaagcta
    22381 tgccagtaaa tgaatatggt caaatgattg gggagtcaat ggaaggttat acaccaggtg
    22441 aactgccttc tattgatttc ttagaagggc gttatgctag gatagaggct ctttcagtgg
    22501 aaaagcatgc ggaggatttg ctagctgttt atgggcctga tacgcctcag gagatgtgga
    22561 cctacctttt tcaggagcca gtagcagata tgggggagct ggttagcctt ttacatcaga
    22621 tgttggctcg taaggaccgt ttttactatg caatcataga caaggcgact ggtaaggctt
    22681 tgggatcttt ttctctcatg cgcattgacc agaataaccg agtaatagaa gtcggagcag
    22741 tcactttttc tccagagcta aggggtacac ggataggaac tgaagctcag tatctcctag
    22801 ctcgctatgt ttttgaggag ctaaactatc gtcgctacga gtggaaatgc gatgccttaa
    22861 atctgccatc cagacgagct gcggagcgtt tgagctttat ttatgaagga accttccgtc
    22921 aggcagtggt ttataaggga cgtacgagag atacggattg gttgtctatg attgataagg
    22981 actggcctca agtcaaagat cgtttggaaa catggttgcg tcctgaaaat tttgataaaa
    23041 atggacagca gtacaagagc ttgagagaac tttaagaggt gttgagatga ttactattaa
    23101 aaagcaagaa attgtcaagc tagaggatgt tttacatctc tatcaggctg tcggttggac
    23161 aaattatacc catcaaccag agatgctgga gcaggcctta tctcattcat tagtaattta
    23221 tctggcactt gatggtgatg ctgtggtggg cttgattcgt ttggttggag atggattctc
    23281 atcagtattg gttcaggatt taatcgtttt accaatctat cagcgtcaag gaattggtag
    23341 tgccttgatg aaagaggctt tagaggatta caaagatgcc tatcaagtcc agctggtgac
    23401 agaagagaca gaaagaacct tgggcttcta tcgttctatg ggctttgaaa tcttatccac
    23461 ctataattgt atagggatga cttggatgaa tcgtaaaaaa taacaaaact tgttttttct
    23521 taagcaaaat ttaaggatgg tctagtatta tatagtcatt aaataaagac ctcctaactt
    23581 tatttaataa aatcctaaac ttttcttttt cataataatc tcccttaact ccacccaatc
    23641 aggtggagtt ttttagctct atttcaggct tttggggact attctaaaaa taatttttcg
    23701 atatttttcg gtatttttcg gattttggtc ggggaattgg cggggacttt tttagcgaat
    23761 ataactaaga aataggtctg tggtcgcttc agctagttca aactcaattt gattgtaagt
    23821 gactgttaat tgaagaactg gaactactgt aataatgatt ttgcttgtct agtagtggcg
    23881 tattaaatga gaagtgacat gtaagattgt ctcttcgttt acgaaatcaa aatttctatg
    23941 aaattgatag aatccctaac gttctcttaa tcttaaccgt cttgtcgtac agcggttgaa
    24001 gaaaatgtaa acctttgaca aaattcgtga actatgggat aataaaaagg aattgagtac
    24061 tagttctata tcataggcta gaaaagaccc caagctcacg accaaataag cttgaggtct
    24121 tttttgacac tatttgtcct tgtttagcca tttatcgact atacgaagaa cgacaccgac
    24181 cacaattggt ccgatgatag ttttgagtac taattccatc atgggctatc tcacctcctt
    24241 tcgtaggcgg tgtagcagtg tcgtagaata ttataccaca taagtgctaa acttaggagt
    24301 cacccaatca ggtggctttt ttgtttgtgg cttggttttt tgatataata gagccatgag
    24361 tagaatttta gataatgaga taatggggga tgaggagtta gtagaacgca cgctccgtcc
    24421 tcagtattta cgtgaatata tcggacagga taaggtcaag gaccagctac aaatctttat
    24481 tgaagctgcc aaaatgcggg atgaagcgct ggatcatgtg ctcttatttg ggcctccagg
    24541 tctcgggaaa acgaccatgg cctttgttat tgccaacgaa ctgggagtca atcttaagca
    24601 gacgtcgggt ccagtcattg aaaaagccgg agatctggta gctattttga atgagttaga
    24661 gcctggggat gtacttttta ttgatgagat ccatcgtttg ccaatgtcag tggaagaggt
    24721 gctttatagt gctatggagg acttctacat agatattatg attggggctg gtgagggtag
    24781 tcgtagtgtt catttggagt taccaccttt taccttgatt ggtgcgacga ctcgggctgg
    24841 tatgctctcc aatccgctac gggcacgttt tgggattaca ggccatatgg agtattatgc
    24901 ccatgctgac ttgacagaaa ttgtcgagcg gacggcagat atttttgaga tggaaatcac
    24961 tcatgaggca gcatctgagt tggccctacg tagtcgtggg acccctcgta ttgccaatcg
    25021 tctcctcaag cgcgtgcgcg attttgccca gataatgggg aatggggtaa ttgatgatat
    25081 tattaccgat aaggctttga ctatgctgga tgttgaccat gaaggtttgg actatgtgga
    25141 tcaaaaaatc cttcgtacca tgattgagat gtacagtgga ggacctgttg gtctaggaac
    25201 tctttctgtg aatatcgccg aagagcgtga gacagttgaa gatatgtatg agccttactt
    25261 gattcaaaaa ggttttatca tgcggacacg gtctggacgg gtggcgactg ctaaggcata
    25321 tgagcactta ggttatgaat acagtgaaaa ataagcaaga aatcttagag gcttttagag
    25381 aaaatccaga tatgatggcc attctgacga tcatccgaga ccttggtctg aaagactcgt
    25441 ggttggcagc aggttctgtc agaaatttca tttggaatct tttgtcagac aaatcccctt
    25501 ttgatcatga aacagatata gatgtgattt tctttgatcc agatttttct tatgaggaaa
    25561 ccttattact ggagaaaaag ctgagagagg attttcctca gtaccagtgg gaattgaaaa
    25621 atcaggtcta tatgcatcag cacagtcctc acactgcttc ctataccagt tctcgtgatg
    25681 ctatgagtaa gtatccagaa cggtgtacgg cagttggact gcgcttgaat gaagaatcag
    25741 attttgaact ctatgcacct tatggtttgg aggatatttt gaattttcaa gttcgtccaa
    25801 ctcctcattt cttagaaaat gaagaccgaa tggaactcta tcaaacacgt ttatccaaga
    25861 aaaattggca ggagaaatgg aaaaatttga tttttaaaaa tacttaagga aactttaagc
    25921 tagggagtgt acactaagtt cataagttaa gaagacctta acttaaactc ctaaaacttt
    25981 ttcataataa tctccctata aaaataaagt cgcccaatca ggcggcttat ttttttgaaa
    26041 aatgggcatg gtgcctgaga ataaatagct tagtgataga agaaaatggg gaaatatggt
    26101 ataatgaaac gatagatttt tgaataggaa taagatcatg tttggatttt ttaagaaaga
    26161 taaggctgtg gaagtagagg ttccgacaca ggttcctgct catatcggca tcatcatgga
    26221 tggcaatggc cgttgggcta aaaaacgtat gcaaccgcga gtttttggac ataaggcggg
    26281 catggaagca ttgcaaaccg tgaccaaggc agccaacaaa ctgggcgtca aggttattac
    26341 ggtctatgct ttttctacgg aaaactggac ccgtccagat caggaagtca agtttatcat
    26401 gaacttgcca gtagagtttt atgataatta tgtcccggaa ctacatgcga ataatgttaa
    26461 gattcaaatg attggggaga cagaccgcct gcctaagcaa acctttgaag ctttaaccaa
    26521 ggctgaggaa ttgactaaga acaacacagg attgattctt aattttgctc ttaactatgg
    26581 tggacgtgct gagattacac aggcgcttaa gttgatttcc caggatgttt tagatgccaa
    26641 aatcaaccca ggtgacatca cagaggaatt gattggtaac tatctcttta ctcagcattt
    26701 gcctaaggac ttacgagacc cagacttgat tatccgtact agtggagaat tacgtttgag
    26761 caattttctt ccatggcagg gagcctatag tgagctttat tttacggaca ccttatggcc
    26821 tgattttgac gaagcggcct tgcaggaagc tattcttgcc tataatcgtc gtcatcgccg
    26881 atttggagga gtttaggagg aaatatgacc caggatttac agaaaagaac cttgtttgca
    26941 gggattgccc tggctatttt cctaccaatt ttaatgattg ggggcctctt gcttcagata
    27001 gcaatcggaa tcatagccat gctagccatg catgaacttt tgaagatgag aggtctagag
    27061 accatgacga tggagggcct cttgaccctc tttgcaacct ttgcattgac cattcccttg
    27121 gagaattacc tgactttttt gccagttgat gggaatgtgg ttgcctatag tgttttgatt
    27181 tcaatcatgt taggaacgac cgtttttagc aagtcttata cgattgagga tgcggttttc
    27241 cctcttgcta tgagcttcta cgtgggcttt ggatttaatg ctttactaga tgctcgtgtt
    27301 gcaggtttgg acaaggctct cttagccttg tgtatcgtct gggcgacaga cagtggtgcc
    27361 tatcttgttg ggatgaacta tgggaaacga aagttagcac caagggtatc gcctaataaa
    27421 acccttgagg gtgccttggg tggtatttta ggagcaattt tagtaaccat tatctttatg
    27481 atagttgaca gtacagttgc tcttccatat ggaatttaca agatgtcagt ctttgctatt
    27541 ttctttagca ttgctggaca atttggtgat ttactagaaa gttcgatcaa acgtcatttt
    27601 ggtgttaagg attctgggaa atttatccct ggacatggtg gtgttttgga tcgtttcgat
    27661 agtatgttgc ttgtatttcc aatcatgcac ttatttggac tcttttaatc aaaagacgga
    27721 ggaaacgcta tgctcggaat tttaaccttt attctggttt tcgggattat tgtagtggtg
    27781 cacgagttcg ggcacttcta ctttgccaag aaatcaggga ttttagtacg tgaatttgcc
    27841 atcggtatgg gacctaaaat ttttgctcac attggcaagg atggaacggc ctataccatt
    27901 cgaatcttgc ctctgggtgg ctatgtccgc atggccggtt ggggtgatga tacaactgaa
    27961 atcaagacag gaacgcctgt tagtttgaca cttgctgatg atggtaaggt taaacgcatc
    28021 aatctctcag gtaaaaaatt ggatcaaaca gccctcccta tgcaggtgac ccagtttgat
    28081 tttgaagaca agctctttat caaaggattg gttctggaag aagaaaaaac atttgcagtg
    28141 gatcacgatg caacggttgt ggaagcagat ggtactgagg ttcggattgc acctttagat
    28201 gttcaatatc aaaatgcgac tatctggggc aaactgatta ccaattttgc aggtcctatg
    28261 aacaatttta tcttaggtgt cgttgttttt tgggttttaa tctttatgca gggtggtgtc
    28321 agagatgttg ataccaatca gttccatatc atgccccaag gtgccttggc caaggtagga
    28381 gtaccagaaa cggcacaaat taccaagatt ggctcacatg aggttagcaa ctgggaaagc
    28441 ttgatccaag ctgtggaaac agaaaccaaa gataagacgg caccgacttt ggatgtgact
    28501 atttctgaaa aggggagtga caaacaagtc actgttacac ccgaagatag tcaaggtcgt
    28561 taccttctag gtgttcaacc gggggttaag tcagattttc tatccatgtt tgtaggtggt
    28621 tttacaactg ctgctgactc agctctccga attctctcag ctctgaaaaa tctgattttc
    28681 caaccggatt tgaacaagtt gggtggacct gttgctatct ttaaggcaag tagtgatgct
    28741 gctaaaaatg gaattgaaaa tatcttgtac ttcttggcaa tgatttccat caatattggg
    28801 atttttaatc ttattccgat tccagccttg gatggtggta agattgtgct caatatccta
    28861 gaagccatcc gccgcaaacc attgaaacaa gaaattgaaa cctatgtcac cttggccgga
    28921 gtggtcatca tggttgtctt gatgattgct gtgacttgga atgacattat gcgactcttt
    28981 tttagataat cgaggaatat tatgaaacaa agtaaaatgc ctatcccaac gcttcgcgaa
    29041 atgccaagcg atgctcaagt tatcagccat gctcttatgt tgcgtgctgg ttatgttcgc
    29101 caagtttcag caggtgttta ttcttatcta ccacttgcca atcgtgtgat tgaaaaagct
    29161 aaaaacatca tgcgccaaga attcgaaaag attggtgctg ttgagatgtt ggctccagcc
    29221 cttcttagtg cagaattgtg gcgtgaatca ggtcgttacg aaacctatgg tgaagacctt
    29281 tacaaactaa aaaaccgtga aaaatcagac tttatcttag gtccaactca cgaagaaacc
    29341 tttacagcta ttgtccgtga ttctgttaaa tcttacaagc aattgccact caacctttat
    29401 caaattcagc ccaagtatcg tgatgaaaaa cgcccacgta atggacttct tcgtacacgt
    29461 gagtttatca tgaaggatgc ttatagtttc cacgctaact atgatagttt ggatagtgtt
    29521 tatgatgagt acaaagcagc ctatgagcgt attttcactc gtagtggttt agacttcaag
    29581 gctattattg gtgacggtgg agccatgggt ggtaaggata gccaagaatt tatggccatt
    29641 acatctgctc gtacagacct tgaccgctgg gttgtcttgg acaagtcagt tgcctcattt
    29701 gacgaaattc ctgcagaagt gcaagaagaa atcaaggcag aattgctcaa atggatagtc
    29761 tctggtgaag ataccattgc ttactcaagt gagtctagct atgcagctaa cttagaaatg
    29821 gcaacaaacg agtacaaacc aagcaaccgt gttgtcgctg aagaagaagt tactcgtgtt
    29881 gcaacgccag atgttaaatc aattgatgaa gttgcagctt tcctcaatgt tccagaagaa
    29941 caaacgatta aaaccctctt ctacattgca gatggtgagc ttgttgcagc ccttctagtt
    30001 ggaaatgacc aactcaacga agtcaagttg aaaaaccact taggagcaga tttctttgac
    30061 gttgctagcg aagaagaagt ggcgaatgtt gttcaagcag gatttggttc acttggacca
    30121 gttggtttgc cagagaatat taaaattatt gcagatcgta aggtgcaaga tgttcgcaat
    30181 gcagttgtcg gtgctaacga agatggctac cacttgactg gtgtgaaccc aggccgtgat
    30241 tttactgcag aatatgtgga tatccgtgaa gttcgtgagg gtgaaatttc cccagatgga
    30301 caaggtgtcc ttaactttgc gcgtggtatt gagatcggtc atattttcaa actcggaact
    30361 cgctactcag caagcatggg agcagatgtc ttggatgaaa atggtcgtgc tgtgccaatc
    30421 atcatgggat gttacggtat cggtgtcagc cgtcttcttt cagcagtgat ggagcaacac
    30481 gctcgcctct ttgttaacaa aacgccaaaa ggtgaatacc gttacgcttg gggaatcaat
    30541 ttccctaaag aattggcacc atttgatgtg catttgatta ctgtcaatgt caaggatgaa
    30601 gaagcgcaag ccttgacaga aaaacttgaa gcaagcttga tgggagctgg ttatgaagtc
    30661 ttgacagatg accgtaacga acgtgtcggt gttaaattta gcgatagtga cttgattggt
    30721 cttccaatcc gtatcactgt tggtaaaaaa gcggccgatg gcattgtaga agttaagatc
    30781 aaggcaactg gtgacaccat tgaggttcat gcagataacg tgcttgaaac gcttgaaatc
    30841 ctaagcaaga aataaaaact ataatcagaa gaaaaacaag gaaaaaatgt aactagtttt
    30901 taccttgttt tttctgtata atgggagaaa tgagtagata aagaggtaaa tgttatgcta
    30961 agatttccaa aggattttgt ctggggatcc tctacttctg gaccgcagac agaaggacgt
    31021 gtagctggtg acggtaaggg agacaatctc tgggattact ggttccaagt ggagccaaat
    31081 cgttactata atgggattgg ttcagataag acatcgactt tttatgaaaa ttgggagcgg
    31141 gatattgagc ttttgttaga gactggtcac acagtctttc ggacttctat tcagtggtca
    31201 cggatttttc cacaaggctg tggaaaagtc aaccctcaag gtgtggattt ttatcgtaag
    31261 gtctttgagg ctattaaggc taaaggaatt cgtctgttag tcaatctcta tcattttgat
    31321 ttaccttttg cccttcaaga ggatggtgat ggttgggaaa ataaggcgac agtctcagcc
    31381 tatgaagact atgctcgttt ttgttttgag acttatggag atttagtgga tcaatggatt
    31441 acctttaacg agcccatcgt tcctgtagaa tttggttatt tttatgatgc ccattatcca
    31501 cataaggtgg atgcagaggc agctgttaag gtagcctatc atacacaatt ggccagcagc
    31561 cgggctgtta aggcttgcca tgaacttttg cctgattcca agattgggat tgtcctcaac
    31621 ttgacaccgg cttatccacg tagccagcat cctgctgatg tcaaggcagc tcgtattgcg
    31681 gccctttttc aggcccaatc tttcttagat ccatctgtct tggggactta tccacaggag
    31741 ttggtagaaa tcttgcatga acacggtctt ttacctgatg ctacagagga agagttggaa
    31801 ctcattcatg ataatacggt ggacttcctt ggtgtgaact actatcaacc tttgcgtgtt
    31861 atggctcctc gatttgctaa gcatccagag agtccactct taccagaaca tttttacgag
    31921 ccttatgtga tgcctggacg taaaatcaat tctcaccgtg gttgggagat ttatgagcaa
    31981 gggatttatg acatcgccca aaatatcaag gaaaattatg gcaatattga atggatgttg
    32041 actgagaatg gtatgggtgt tgaaggggaa gaaaaattcc gtcaagatgg aatgattcaa
    32101 gatgattacc gtattgactt tgtaaaaggt catcttcgtg aacttcaccg tgccattgaa
    32161 gatggtgcca actgtaaggg ctacttgatt tggaccttta ttgactgctg gtcatggctc
    32221 aacagctata aaaatcgcta tggtttggtc gaattagact tggaaacgca agaacgtcgt
    32281 ctgaagaaat caggccactg gttcaaaaaa ttaagcgata ataatggatt ttaaaaagga
    32341 ctctgactga ttatcccaat cggtcagagt tttttgctta caggagctta atttgaacta
    32401 taccaatttt tactcttgac aagtgaaaga aacaagtata tactgttttt gctgattcta
    32461 taaaagatga attagactat accaatttta aggagaaagc acagcttgcc tgtgtcgtat
    32521 atactatgtg tggaattgtt ggtgttgttg gaaacacaaa tgcaactgat attttgattc
    32581 aagggcttga aaagcttgaa taccgtggct atgattctgc gggaattttt gtcctagatg
    32641 gtgctgataa ccatttggtg aaggctgttg gtcgtatcgc agaattgtct gccaagacag
    32701 ctggtgttga gggaacaact ggtatcggac atactcgttg ggcaactcat gggaaaccaa
    32761 cggaagacaa tgctcaccca caccgctctg agacagaacg ttttgtcttg gttcacaatg
    32821 gggtgattga aaactacctt gaaattaaag aagaatacct tgctgggcac cacttcaaag
    32881 ggcaaacaga tacggaaatc gccgtacatt tgattggaaa atttgcggaa gaagacggtc
    32941 tctcagttct tgaagccttt aaaaaagctc ttcatattat ccgtggttca tatgcctttg
    33001 ccttgattga ctctgaaaat ccagatgtca tctatgtagc gaaaaacaaa tctccacttt
    33061 tgattggtct tggggaaggc tacaatatgg tctgctcaga tgctatggct atgattcgtg
    33121 aaaccaacca atacatggaa attcatgacc aagagttggt aatcgtcaag gctgatagcg
    33181 tggaagttca agactatgat ggaaatcgtc gtgagcgtgc tagctacact gctgaacttg
    33241 acttgtcaga tatcggtaag ggaacttacc cttactacat gctcaaggaa attgacgagc
    33301 aaccaactgt tatgcggaaa ctcatccaag cctacacaga tgaggctggt caagttgtcg
    33361 tagacccaga tatcattaag gctgttcaag acgcagaccg catctacatc cttgcagctg
    33421 gaacatctta ccatgcagga tttgcttcta agaagatgtt ggaagaattg acagatacac
    33481 cagttgaact tggaatctca tctgagtggg gctacggtat gccacttctc agcaagaaac
    33541 cactcttcat ctttatcagc caatctggtg aaacagcgga tagtcgtcaa gttttggtca
    33601 aggctaatga aatgggaatt ccaagcttaa cagtgacaaa tgttccaggt tcaaccctct
    33661 cacgtgaagc caactatacc atgctccttc acgcaggtcc tgaaattgcc gtggcatcaa
    33721 ctaaagccta tacagcgcaa atcgcagccc ttgccttcct tgcaaaagca gtcggagaag
    33781 caaatggtaa tgctaaagcg caagcctttg acctggttca tgaattgtca atcgtagctc
    33841 agtctattga atcaactctt tcagagaaag aaaccattga agccaaggtt cgtgaacttc
    33901 ttgaaacaac tcgtaacgcc ttttacatcg gacgtggtca agattattac gtagccatgg
    33961 aagcaagtct caaactcaaa gagatttctt atatccagtg tgaaggtttt gcggcaggag
    34021 aactcaagca cggaaccatt gccttgattg aagaaggaac gcctgttttg gctctcttgt
    34081 cagatccagt tcttgccaac catactcgtg gaaatatcca agaggtcgca gcccgtggtg
    34141 ccaaagtcct cactatcgca gaagagaatg tagccaaaga taccgacgat atcgtcctta
    34201 cgaccgtaca tccatacctc tcaccaattt caatggtcgt accaacgcaa ttagtcgctt
    34261 actttgcaac cctccaccgt ggcctcgatg tggacaaacc acgtaacctt gccaagtcag
    34321 taacggtaga ataagctaaa aaagtctagt tatctaggct ttttcttgtg agcaaattgg
    34381 ttgcttgtac tcaagattcg tgttatactc ttagaaaatc tcttcaaacc acgtcaccgt
    34441 cgccttgccg taggtatggt tactga
//
LOCUS       DAVBEM010000019        34347 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVBEM010000019 DAVBEM010000000
VERSION     DAVBEM010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.019"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            <1..4786
                     /locus_tag="VQ548_000944"
     CDS             <1..4786
                     /locus_tag="VQ548_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2653813.1"
                     /translation="QGERGLTGAKGEKGDQGERGLTGAQGEKGDRGERGLTGAKGEKG
                     AQGQAGRDGVTPTVTVKDNKNDGTHTITINDGRGNVTSTVVRDGFDGASPLVATQRND
                     ADKTTTVIFYYDKNGNNELDASDKKLKEVVIADGAKGEKGDKGEQGLQGRDGEQGPKG
                     EDGKTPTVKVTDGQDGTHTITINDGKGGITTTVVRDGFDGASPLVSTHRNEADKTTTV
                     IFYYDLNDNNQFDEGDTKLKEVVIADGKQGPKGDKGDNGKDGFTPEVTVTDNNNGTHT
                     ITITQPDNRPSLTTIVKNGEDGKTPKVKAERDDAKKQTTLTFYIDKDGDGSYTAGKDE
                     LVQTTVVKDGQDGAAGASGRDGKEVLNGKVDPTTEGKDGDTFVNTQTGDVFVKKGNTW
                     EPAGNIKGPKGDKGADGAKGEKGAQGERGLTGAQGVKGEKGDQGERGLTGSKGEKGDQ
                     GERGLTGAQGAKGDKGEQGLQGRDGAQGPKGADGQRGPAGPQGPKGEQGNPGTPGKDG
                     KSLIAVKNGTETKVYVEDPARPGQPLNPNQPLATITDGRNGTNGQSPTITATRSVQNG
                     KNGVLVTITPVGGRPQTTFVEDGQKGADGKTPTVTITEGQNGTHTLTVHNPGSPDVTT
                     TIRDGATGQAGRDGKDVLNGKVNPQPNQGKNGDKYINTETGDVYVKNNGNWDKEGNIK
                     GPKGDKGADGAKGEKGDQGERGLTGAQGAKGADGAVGRDGRDGKDVLNGKANPEAHQG
                     KDGDKYVNTETGDVFVKNNGNWDKEGNIKGPKGDKGERGEDGKTPEVTVTPGKDGHST
                     DITFTVPGKDPVTVNVKDGENGLNGKTPKVDLLRVQGKNGNPSHTIVTFYTDENNDGK
                     YTPGTDELLGSEMIKDGAKGADGRDGKSLLTVKDGKETKVYQEDPANPGQPLNPEKPL
                     AVIRDGVDGKSPTVTAVRKDEAGHKGVEITVDNHDGSQPTTVFVQDGAKGETGATGQD
                     GQTPTITTQRGQDGQSTVVTITTSGKDPVTFTVKDGKNGKDGRAPKIKVEDITSPSRI
                     RRDTDAAATPTRNGIRVTVYDDVNDNGVYDEGVDKVLNSKDIYNGIDGRDGSAPTITT
                     KDNGDGTHTITVQNPDGSESTTVVKDGKDGKTANITTTENPDGSHTITVTNPDGSTKE
                     TVVKNGKDGKTPKVEVTDNNDGTHTVKVTDGDGNVTNAIIKDGKDGKAATATTTENPD
                     GSHTVTITNPDGTKNEFVVKNGRDGVDGRTPTASVRDNGDGSHTIVITNPEGVTTETT
                     VRDGKSPKVTITDEQNGTHKISVLNGDGTTTTTTVRDGREPKLEVIDNNDGSHTIKVT
                     GADGKGTTTTIFDGKSPKANIVDNGDGTHTLTIVDSDGREYKSIIKDGKDGKDSVSPT
                     VTVKNNNDGTHVVTITNPDGSKTEMVIKDGKDGKSPKVSVEDNGDGSHTITIINSDGT
                     VTKTVIKDGRDGRDGRDGKDGKDGKDGKCGCQDKPVTPSNDKPVPPTPNVPTPEVPVK
                     PVPAQPTPNVPTPEVPVQPTPAVPTPEVPVKPVPAVPEQPVVPTPAQPATPVNANPVA
                     PTTGKENRGDKLPETGSQSDYISVLLGSGILLSLYVGRRKEA"
     gene            complement(5023..5571)
                     /locus_tag="VQ548_000945"
     CDS             complement(5023..5571)
                     /locus_tag="VQ548_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2653814.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            5892..6380
                     /locus_tag="VQ548_000946"
     CDS             5892..6380
                     /locus_tag="VQ548_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HET2653815.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            6377..7564
                     /locus_tag="VQ548_000947"
     CDS             6377..7564
                     /locus_tag="VQ548_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2653816.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            7557..7922
                     /locus_tag="VQ548_000948"
     CDS             7557..7922
                     /locus_tag="VQ548_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2653817.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            7938..9284
                     /gene="asnS"
                     /locus_tag="VQ548_000949"
     CDS             7938..9284
                     /gene="asnS"
                     /locus_tag="VQ548_000949"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HET2653818.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            9437..9727
                     /locus_tag="VQ548_000950"
     CDS             9437..9727
                     /locus_tag="VQ548_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HET2653819.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            9739..10209
                     /gene="ssbA"
                     /locus_tag="VQ548_000951"
     CDS             9739..10209
                     /gene="ssbA"
                     /locus_tag="VQ548_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HET2653820.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            10241..10480
                     /locus_tag="VQ548_000952"
     CDS             10241..10480
                     /locus_tag="VQ548_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HET2653821.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            10775..12175
                     /locus_tag="VQ548_000953"
     CDS             10775..12175
                     /locus_tag="VQ548_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HET2653822.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSYVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDVIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            12177..12536
                     /locus_tag="VQ548_000954"
     CDS             12177..12536
                     /locus_tag="VQ548_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HET2653823.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            12590..13339
                     /locus_tag="VQ548_000955"
     CDS             12590..13339
                     /locus_tag="VQ548_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HET2653824.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICHSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            13329..13628
                     /locus_tag="VQ548_000956"
     CDS             13329..13628
                     /locus_tag="VQ548_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HET2653825.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALFKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            13699..14634
                     /locus_tag="VQ548_000957"
     CDS             13699..14634
                     /locus_tag="VQ548_000957"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HET2653826.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            14721..15233
                     /locus_tag="VQ548_000958"
     CDS             14721..15233
                     /locus_tag="VQ548_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HET2653827.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGAVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            15270..15865
                     /locus_tag="VQ548_000959"
                     /pseudo
     CDS             15270..15865
                     /locus_tag="VQ548_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            15966..16160
                     /locus_tag="VQ548_000960"
     CDS             15966..16160
                     /locus_tag="VQ548_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET2653828.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(16206..17651)
                     /locus_tag="VQ548_000961"
     CDS             complement(16206..17651)
                     /locus_tag="VQ548_000961"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HET2653829.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            17757..19379
                     /locus_tag="VQ548_000962"
     CDS             17757..19379
                     /locus_tag="VQ548_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET2653830.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            19583..21541
                     /locus_tag="VQ548_000963"
     CDS             19583..21541
                     /locus_tag="VQ548_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2653831.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGFLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFATAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            21713..22648
                     /locus_tag="VQ548_000964"
     CDS             21713..22648
                     /locus_tag="VQ548_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2653832.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILLLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTVYSRSKGSSVALENLLAVPKEKFE"
     gene            22673..23325
                     /locus_tag="VQ548_000965"
                     /pseudo
     CDS             22673..23325
                     /locus_tag="VQ548_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            23483..24577
                     /locus_tag="VQ548_000966"
     CDS             23483..24577
                     /locus_tag="VQ548_000966"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET2653833.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            24585..25751
                     /locus_tag="VQ548_000967"
     CDS             24585..25751
                     /locus_tag="VQ548_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2653834.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEIQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            25844..28942
                     /locus_tag="VQ548_000968"
     CDS             25844..28942
                     /locus_tag="VQ548_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2653835.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            28990..29607
                     /locus_tag="VQ548_000969"
     CDS             28990..29607
                     /locus_tag="VQ548_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET2653836.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            29617..30951
                     /locus_tag="VQ548_000970"
     CDS             29617..30951
                     /locus_tag="VQ548_000970"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HET2653837.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            30961..31425
                     /locus_tag="VQ548_000971"
     CDS             30961..31425
                     /locus_tag="VQ548_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2653838.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     DLDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            31422..31916
                     /locus_tag="VQ548_000972"
     CDS             31422..31916
                     /locus_tag="VQ548_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2653839.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            31997..33646
                     /gene="mltG"
                     /locus_tag="VQ548_000973"
     CDS             31997..33646
                     /gene="mltG"
                     /locus_tag="VQ548_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HET2653840.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMTDSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDIIS
                     DTSRRSRREGAKPVNPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPIDA
                     NSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQKSM
                     STEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAFLA
                     KVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDEML
                     AAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDMPL
                     QSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIESSI
                     NQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            33717..34199
                     /gene="greA"
                     /locus_tag="VQ548_000974"
     CDS             33717..34199
                     /gene="greA"
                     /locus_tag="VQ548_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HET2653841.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
BASE COUNT        10715 a         6373 c         7776 g         9483 t
ORIGIN      
        1 ccaaggtgaa cgcggtttaa ctggagctaa aggtgaaaaa ggggaccaag gtgaacgcgg
       61 tctcactgga gcccaaggtg aaaaaggaga ccgaggcgaa cgtggtttaa ctggagctaa
      121 aggtgaaaaa ggagcccaag gtcaggcagg tcgtgacggt gtaactccaa ccgtaaccgt
      181 taaagataat aaaaatgacg gcactcatac tatcactatt aacgacggta gaggtaatgt
      241 tacaagtact gttgtaagag atggtttcga tggcgcaagt ccattagttg cgactcaacg
      301 aaatgacgca gataagacaa caactgttat cttctattac gataaaaatg gaaacaatga
      361 attagatgct tctgataaga aattaaaaga agttgtaatt gcagatggtg ctaaaggtga
      421 aaaaggggac aaaggtgaac aaggtcttca agggcgtgat ggtgaacaag gaccaaaagg
      481 agaagatggg aaaaccccaa cagttaaagt aactgatggt caagatggaa cgcatacaat
      541 tacaattaac gatggtaaag gtggtataac tactacagta gtaagagatg gatttgatgg
      601 tgcaagccct cttgtttcta ctcatagaaa tgaagcagat aaaacaacaa ctgttatttt
      661 ctattatgat ctaaatgata ataatcaatt tgatgaagga gatacaaaac ttaaagaagt
      721 tgttatcgca gatggaaaac aaggaccaaa aggtgacaaa ggtgataacg gaaaagatgg
      781 attcacacca gaagtaacag ttacagataa caataacgga acacacacca tcacaatcac
      841 acaaccagac aacagaccat cattaacaac aatcgttaaa aacggtgaag atggaaaaac
      901 accaaaagtc aaagcagaac gagatgatgc gaagaaacaa acaacattaa cattctacat
      961 tgacaaagat ggagatggaa gttacacagc aggaaaagac gagttagttc aaacaacagt
     1021 agttaaagac ggacaagacg gagctgcagg agcatctgga cgtgatggaa aagaagtatt
     1081 aaacggaaaa gtagacccaa caacagaagg taaagatgga gacacattcg taaatacaca
     1141 aacaggagat gtattcgtta agaaaggtaa cacttgggaa ccagcaggaa acatcaaagg
     1201 accgaaaggt gacaaaggtg cagatggtgc caagggtgaa aaaggagccc aaggagaacg
     1261 cggcctgact ggagcgcaag gtgtcaaggg tgaaaaggga gatcagggtg aacgcggtct
     1321 aactggatct aaaggtgaaa aaggagacca aggtgaacgc ggtttaactg gagcgcaagg
     1381 tgccaaaggt gacaaaggtg aacaaggtct tcaaggtcgt gatggagctc aaggaccaaa
     1441 aggcgcagat ggacaaagag gaccagcggg accacaagga ccaaaaggag aacaaggtaa
     1501 tccaggaact ccaggtaaag atggaaaatc tctaattgct gttaaaaatg gaactgaaac
     1561 aaaagtctat gtagaggatc cggctagacc aggacaacca cttaatccaa accaaccatt
     1621 agcaactatc actgatggaa gaaacggtac taatggacaa tcaccaacaa ttacagcgac
     1681 acgaagtgtg caaaatggca aaaatggtgt attagtaaca attacaccag taggaggtcg
     1741 tccacaaaca acatttgtag aggatggaca aaagggtgct gatgggaaaa ccccaacagt
     1801 aacaataact gaggggcaaa acggcacaca tacattaacg gttcataatc caggaagtcc
     1861 agatgtgaca actacgatcc gtgatggagc tacaggacaa gcaggtcgtg atggtaaaga
     1921 tgtattaaac ggaaaagtaa atccacaacc aaaccaaggt aaaaatggag ataaatatat
     1981 taataccgaa accggtgatg tctatgttaa aaacaatgga aactgggata aagaaggcaa
     2041 catcaaaggc cctaaagggg acaaaggtgc agatggtgct aaaggcgaaa aaggagacca
     2101 aggcgaacgc ggcctaactg gagcgcaagg agctaaaggt gcggatggcg cagtaggtcg
     2161 tgatggacgt gacggtaaag acgtgttgaa cggcaaagct aacccagaag cacatcaagg
     2221 taaagacggc gataaatacg ttaatacaga aacaggcgac gtcttcgtta agaataacgg
     2281 caactgggat aaagagggca acatcaaagg ccctaagggt gacaaaggtg aacgcggaga
     2341 agatggtaag actccagaag taactgtaac tccaggtaaa gatggccata gtactgacat
     2401 tacattcact gttccaggta aagatccagt tacagtaaat gttaaggacg gagaaaatgg
     2461 tctgaacggt aaaactccaa aagttgattt acttcgtgtc caaggaaaaa acggaaatcc
     2521 atctcataca attgtgacat tctatacaga tgaaaacaat gacggcaaat atacaccagg
     2581 aactgatgaa cttctaggtt cagaaatgat taaagatggt gctaaaggcg cggacggacg
     2641 agatggtaaa tcattgctta ctgtcaagga tggtaaagaa actaaagttt accaagaaga
     2701 tccagctaac ccaggacaac cattaaatcc agaaaaacca cttgcggtaa ttagagatgg
     2761 agtagatgga aaatcaccta cagttacagc tgttcgtaaa gatgaagcag ggcataaagg
     2821 tgtagaaatc actgttgata accatgatgg ttcacaacca actacagtct ttgttcaaga
     2881 tggtgctaag ggagaaactg gtgcaaccgg tcaggatgga caaactccta caatcactac
     2941 tcaacgtgga caagatggcc aaagcactgt tgtaactatc acaacatcag gtaaagatcc
     3001 agtaaccttc actgtaaaag atggtaagaa tggtaaagat ggccgtgcac cgaaaatcaa
     3061 agtagaagat attacttcac cttcaagaat tagacgcgat acagatgctg ctgcaactcc
     3121 aacgcgtaac ggtatccgtg ttacagttta tgatgatgtt aatgacaatg gggtatacga
     3181 cgaaggtgtc gataaagtat taaatagtaa agatatttat aacggtatag atggacgtga
     3241 tggttcagct ccaactatta ctacaaaaga taatggagat ggaactcaca ctatcacagt
     3301 tcaaaaccca gatggttctg aatcaacaac agttgttaaa gatggtaaag acggtaaaac
     3361 tgcgaatatc actacaacag aaaacccaga tggaagccac acaattacgg tgacaaatcc
     3421 agatggttca actaaagaaa ctgttgttaa aaacggtaaa gacggtaaga ctcctaaagt
     3481 tgaagtaacg gataacaacg atggaactca tactgttaaa gttacagatg gagacggcaa
     3541 tgttaccaac gctatcatca aagatggtaa agacggtaaa gctgcaacag caacaactac
     3601 tgaaaatcca gatggaagcc acacagtaac aatcactaac ccagacggaa ctaagaatga
     3661 gtttgttgtt aagaatggac gtgacggtgt tgacggacgt actccaaccg catctgttcg
     3721 tgataatgga gacggaagtc atacaatcgt tattacaaat ccagaaggtg tgacaactga
     3781 aaccacagtt cgtgatggta aatcaccaaa agtgactata actgatgaac aaaatggaac
     3841 tcataagatc tctgttctaa atggtgacgg aacaactaca acaactacag ttcgtgatgg
     3901 tagagaacca aaacttgaag ttattgataa caacgatggt tcacacacta ttaaagtgac
     3961 aggtgctgat ggtaaaggaa cgacaactac aatctttgat ggtaaatcac caaaagcgaa
     4021 catcgttgat aacggagatg gaactcatac attaacaatc gtagattctg atggtcgtga
     4081 atacaaatct attatcaaag atggtaaaga cggcaaagat agcgtttcac caactgtaac
     4141 tgttaaaaat aataacgatg gaactcacgt tgttacaatc actaatccag atggaagtaa
     4201 gacagaaatg gtgattaaag acggtaaaga tggtaaatca ccaaaagttt ctgttgaaga
     4261 taatggtgat ggtagtcata caatcacaat catcaattct gatggaactg tgacaaaaac
     4321 agttattaaa gatggtagag atggacgtga tggtcgagac ggcaaagacg gtaaagacgg
     4381 taaagatgga aaatgtggat gccaagacaa accagtaaca ccatcaaatg acaaaccagt
     4441 tcctccaaca ccaaatgtgc cgacaccaga agtaccggtt aaacctgtgc cagcgcaacc
     4501 aacaccaaat gtaccgacac cagaagtgcc agtacaacca actccagctg ttccaacacc
     4561 agaagtaccg gttaaaccag taccagcggt tccagaacaa ccagtagtac caacaccggc
     4621 tcaaccagca actccagtaa atgctaaccc agtagcacca actacaggta aagaaaaccg
     4681 tggggacaaa ttacctgaaa ctggaagcca atctgattat atctctgttc ttttaggtag
     4741 cggtattcta ttgagcctat atgtaggacg aagaaaagaa gcttaatcag ccaaaagcag
     4801 tcactaattt ctcgaaagaa gatgataagt gatagatctc gaatgaaaga atattcttag
     4861 aatgattttc ctatgatgga aaagactgct aaaaaccttg agtggtaacg ctcaaggttt
     4921 ttttggatgg ctgatgtttg tctgaaaatc ttgattgaga aataaaaagc caccctatta
     4981 ggtggctata attgatttag actttctaaa attttctatt ttttactgaa tcgcttcgac
     5041 caagtcttga gcttgttttt caagtgagtt taggactgtt tcttcaagaa ccaattttcc
     5101 gtctgcccag gcagagtcat taacacgtgc agcagtgaaa tcaccaacgc cttgtgtacg
     5161 gataaatggc aagaggtctt tgtagatagc gaaaagttga tcgtgccctg cattggctac
     5221 agatgatacg gtgacaaact tgtcttgaag ggcagaaacg ccacgcgtat cagacaagtc
     5281 aagggcacga gatagccagt caagcaagtt ttttactgta ccagggatag agaagttgta
     5341 gactggagag aaaatccaga tagcatccgc aacgagaact gcttcacgag cagcagctac
     5401 agctggatgt gttggaactt ccaaatcttg gctgaagaga ggaagggctg aataatcaag
     5461 gtagctaact tccgctttac cagcaagtgc tttctcagct tcgagcgcca tttggtggtt
     5521 gaaagaacct tgacgtagtg atccgacgat aaataatact tttttagaca tgatgtgtct
     5581 cctttttctt caaattttga gaactctctc gttgttataa aatacattac aacaaaacaa
     5641 aagaacttgc aagaaatttg ctcagagttt atttgaaaat tgtaaaattt cggaaactct
     5701 agtcatttgt gactgaaaaa gtaagaactg tttcactttc aaaatcggtt ttgtttgaag
     5761 ggagaaatag aattggttgc tcaaagcaca gctttgaggt tgcagataaa gctgacgtgg
     5821 tttgaagaga ttttcgaaga gtattcttat attcacttgt aataaagctt aatagatggt
     5881 aaaatagacg agtgaaaaaa agacaaaaca aagcaaaaaa taatctactg tggcagtatg
     5941 gtctagggat gacgattttg tttgtggtta tcagtgcttc ctttctgtat atggtttctc
     6001 ttagcatgaa accctatcaa acagctaaaa gtgaaggaga aaaattagct cagcagtatg
     6061 caggattaga gcaggccgat caggttgatt tatacaatgg cttggaatct tattacagcg
     6121 ttcttggtcg taataaacag caagaagcac ttgctgttct gattggaaaa gatgatcata
     6181 agatttacgt ttatcagcta aatcagggtg tttcacaaga aaaagcagaa acggtttcta
     6241 aggaaaaggg agctggcgaa attgacaaga ttatctttgg tcgttatcaa gataagccaa
     6301 tctgggaagt caagtcagga tctgattttt atctagtaga ttttgaaaca ggagcattgg
     6361 tcaacaagga gggcctatga aattatccaa ccgtgtttta gaaatggaag aaagtgtgac
     6421 tttggctgct ggagcccgtg ccaaagcact gaaggctgag ggtagagata ttttgtctct
     6481 aaccttgggt gagccagatt tcactactcc caaaaatatc caagatgccg ccattgcatc
     6541 gattcgagat gggcgtgctt ctttttatac agtaacctca ggtctgccag agcttaaggc
     6601 ggcggtcaat agctactttg agcgctttta cggctattct gtagcgtcaa atcaagtgac
     6661 agtcgctgcg ggagccaaat attctctcta taccttcttt atggctgtgg tcaatccagg
     6721 tgatgaagtc atcatcccaa ccccatactg ggttagctat ggagatcagg tcaagatggc
     6781 agaaggcgtt cccgtctttg tttctgctaa ggaagacaat cactttaagg tgaccgtaga
     6841 gcagttagaa gcagctcgca ctgacaagac caaggttttg gtgctgaatt cgccatctaa
     6901 tcccacaggt atgatttaca cccgtgagga actcttggca attggaaact gggctgtaga
     6961 aaatgatatt ctcatcctag cagatgatat ctatggccgc ttggtttata atggtcatga
     7021 gttcacaccg atttctagcc tatcggaagc gattcgcaag caaacagtgg tcatcaatgg
     7081 tgtgtctaaa acctatgcca tgactggttg gcggattggt tatgccgttg gagaagcaga
     7141 cattatcgct gccatgtcca agattgcagg tcaaacaact tcgaatccgt cagcagtagc
     7201 ccaatatgca gcagttgagg ctctatcagg tgagcaagat actgtagaaa gcatgcgtca
     7261 ggcctttgaa gaacgtctta ataccatcta tcccctcctt gcagaagtgc caggatttga
     7321 agtggtcaaa ccgcaagggg ccttctatct cttcccaaat gtcaaaaagg ccatggagat
     7381 gaaaggctac acggatgtga cagactttac aactgttatc ttagaagaag ccgaagtggc
     7441 cttggtaaca ggagctggat ttggagcacc agaaaatgtc cgcctcagct atgcgacaga
     7501 cctagacacg cttaaagaag cagtcgaacg cttgaaagca tttatgggta gtgagaatga
     7561 ttgatcattt tgagattaag gtaaaggatt tacaaatttc agaaggattt tataggagtt
     7621 ttctcgctcc tttggactat aaattggctt ttaagactag ttctctaatt agttttctat
     7681 ccccgaacag ccctcatcct ggtggtgatt tttggctgac tcagggaaca caagatcctg
     7741 ttcattttgc ttttttagca gaaaataagg aagaagttca ggcttgttat gaggctggct
     7801 tagaggcagg tgggcgagac aatggggctc ctggttatcg aagtgagcat ccgatttact
     7861 atgctgcttt tatgattgac ctggatggga acaatataga ggtggtttgc cataaagaat
     7921 aaaaaagaaa aggaaaaata atgacaaaac gtgtaacgat tattgacgta aaagactatg
     7981 ttggtcagga agtgacgatt ggcgcttggg ttgccaacaa atcaggaaaa gggaaaatcg
     8041 ctttcttaca attgcgtgat ggaacagcct tctttcaagg tgtggctttt aaaccaaact
     8101 ttgtcgaaaa atttggtgaa gaagtgggac ttgagaagtt tgatgttatc aaacgcttga
     8161 gccaagaaac gtctgtttat gtgacaggta ttgtcaaaga ggacgaacgt tctaaatttg
     8221 gctatgagtt ggacatcaca gacatcgaag tgatcggtga atctcaagac tacccaatca
     8281 caccaaaaga acacggaaca gactttttga tggataaccg tcacttgtgg ctacgctctc
     8341 gtaagcaagt agctgtgttg caaatccgta acgctattat ctatgcaact tatgagttct
     8401 ttgacaagaa cggttttatg aagtttgaca gcccaattct ttcaggaaat gcggcagaag
     8461 attctacaga actctttgaa actgactact tcggaacgcc agcctacttg agccaatcag
     8521 gtcaacttta cctagaagca ggggctatgg ctcttggtcg tgtctttgac tttggtccag
     8581 ttttccgtgc tgaaaaatca aaaacacgcc gtcacttgac tgagttctgg atgatggatg
     8641 ctgagtactc atacttgaca catgatgagt cgcttgactt gcaagaagct tatgtgaaag
     8701 ctcttctaca aggtgttctt gaccgcgcgc ctcaagcctt ggaaaccttg gaacgtgata
     8761 cagaactctt gaaacgctac attgcagagc cattcaaacg tatcacttac gatcaagcca
     8821 ttgacctctt gcaagagcat gaaaatgatg aagatgctga ctacgagcat cttgagcatg
     8881 gtgatgactt tgggtcacca cacgaaactt ggatttcaaa ccactttggt gtgccaacat
     8941 ttgtcatgaa ctatccagca gccatcaagg ccttctacat gaaaccagtt cctggaaatc
     9001 cagagcgcgt gctttgtgca gacttgcttg ctccagaagg ctatggagaa attatcggtg
     9061 ggtctatgcg tgaggaagat tacgatgccc ttgtcgctaa gatggatgaa cttggcatgg
     9121 atcgtacaga atatgaattc taccttgacc ttcgtaaata cggtacagtt ccacacggag
     9181 gatttggtat cggtatcgaa cgtatggtaa ccttcgcagc aggaacaaaa catatccgtg
     9241 aagctattcc attcccacgt atgttgcacc gtatcaaacc ataagaacag gaaaacgccc
     9301 atgtggcgtt ttttcgaatt ctagtgtttt tacttgcgta aaaaaaattt ttctagtata
     9361 atagtttatt gtgagcgaac ctcacttacc ccttgcaaag tcttggggtc attagaccaa
     9421 aaggaggaac atatcaatgg ctaaatacga aattctttat atcattcgtc caaacattga
     9481 agaagaagct aaaaacgctt tggtagcacg ttttgactct attttgactg acaacggtgc
     9541 aactgttgtt gaatcaaaaa cttgggaaaa acgtcgtctt gcatacgaaa tccaagattt
     9601 ccgtgaagga ctttaccaca tcgttaacgt tgaagcaaat gacgatgcag ctcttaaaga
     9661 gtttgaccgt ctttcaaaaa tcaacgctga cattcttcgt cacatgatcg tcaaaattga
     9721 cgcgtaagaa ggtaaactat gattaacaat gttgtacttg tagggcgtat gacacgtgac
     9781 gctgaattgc gttatacccc atcaaatgta gcagttgcga cttttactct tgcagtaaac
     9841 cgtacattta agagtcaaaa tggtgaacgt gaggctgatt ttatcaatgt cgttatgtgg
     9901 cgccaacagg ctgaaaatct tgctaactgg gctaaaaaag gctcacttat cggggtgaca
     9961 ggtcgtatcc agactcgtag ttacgataac cagcaaggac aacgtgtcta cgtgacagag
    10021 gtcgtggctg agaatttcca aatgttggaa agccgtagtg tgcgtgaggg tcacacaggt
    10081 ggagcttact ctgcaccaac tgcaaactat tcagcaccta caaattcagt accagacttt
    10141 tcacgtaatg aaaatccatt tggagcaaca aacccattgg atatttcaga tgatgattta
    10201 ccattctaat ggacaactaa acttataaag gagaaaaaac atggctcaac aacgtcgtgg
    10261 cggattcaaa cgccgtaaaa aagttgatta catcgcagca aacaaaattg aatatgttga
    10321 ttacaaagat actgagcttc ttagccgttt cgtttcagaa cgtgggaaaa tccttcctcg
    10381 tcgtgtaaca ggaacttcag ctaaaaacca acgtaaagta acaacagcta tcaaacgcgc
    10441 tcgcgtaatg gctttgatgc ctttcgtaaa cgaagattaa agaaaagacc cggttgggtc
    10501 tctttttcat gaacttgaaa acaagaaagc gaattaagac cccaacgggt cttttttcac
    10561 aagctttgaa atgagagagc gagttaggct cagtggctcc ctttttacga gtttgaaaac
    10621 aagagaacac attaaaagca cgatggagct ttttcataaa tatgtctttt ttttcatcca
    10681 agaaattaaa ataaaaatga taaacttttt gaaaataggg gatttgccta ctttatgata
    10741 taatggaaag agttagattg aaagaggtag tgagatggac gcgaaattaa gatacaaggc
    10801 aaagaagatc aagattgtct tttttgatat tgatgataca ttgcggaatt caaagacagg
    10861 gtttattcca actacaattc ccactgtttt taaacagttg cgtgaaaaag gaattttaac
    10921 aggaatcgcc tctggacgtg gcatttttgg tgttgttcca gagattcgtg atctcaaacc
    10981 tgactttttt gtaactttga atggggctta tatcgaagat aaaaaaggtc aggtcattta
    11041 tcagcatcag attgaaaagt catatgttga ggagtatatc tcttgggcta agcaagaagg
    11101 aattgagtat ggcttggttg ggagtcatga tgccaagttg tcgactcgca ccgatatgat
    11161 gagtgaagct atcaatccaa tttatcccga cttagatgta gatcccgatt tccatgaaaa
    11221 agaagatatc tatcagatgt ggacttttga agataaggga gatgacttgc acttgcctga
    11281 cagtctctca gacaaacttc gcatggttcg ttggcatcaa cattcgtctg atattgtgcc
    11341 gatttcaggc tccaaagcga cgggggtgga aaaggttgtg gaacaccttg gcttgaaacc
    11401 agagaaggtc atggtttttg gagatggtct caatgacttg gaactctttg attatgctgg
    11461 aatcagcgtt gccatgggaa tttctcatga taaaatcaaa gaaaaagcag attatattac
    11521 aaaaacatta gaagaagatg gcatttttga tgccttagaa gtatttggta tggtagaaaa
    11581 agaattgcat tttccacaag tagacattga aacagtagaa ggtcctcttg cgactattaa
    11641 gaccaatcac ggagacttac gtatcaagct tttccctgaa catgctccta aaacagtggc
    11701 taactttgta tctctttcaa aagatggcta ctatgatggt gtcattttcc accgtattat
    11761 caaggacttt atgatccaag gtggagaccc aactggaact ggtatgggtg gcgagtcaat
    11821 ctacggcgaa tcttttgagg atgaattctc agaagagctt tacaatatcc gtggtgctct
    11881 ttccatggca aatgctggtc caaataccaa cggcagccag ttctttatcg tgcaaaacca
    11941 acacctacct tattctaaga aagaaattac tcgtggtggt tggccagaac cgattgcaga
    12001 aatctatgcc aatcaaggtg ggacacctca cctagaccgc cgtcacacgg tttttggtca
    12061 gttagctgat gaagcatctt acgctgtctt ggatgtcatt gctgctgttg agacaggagc
    12121 tatggacaag ccagttgaag atgttgtaat tgaaactatt gaaatcgagg actaagatga
    12181 aaatcggtga taagctaaag gggcgtatta cagggattca gccctacggt gcctttgttg
    12241 agttagagac gggtgatacg gggctgattc acatttcaga aattcggaca ggatttattg
    12301 aaaatattca tgaaaccttg aaagtcgatg aagaggttca agttcaggta gtggatttag
    12361 atgaatttac ggggaaagcc agtctttcta tccgcacttt ggaggaagaa aagtaccagt
    12421 ttcctagacg gagacgcttt tcaagcgacc gctttaacta cggttttgct ccctttcgac
    12481 gaatgctacc aatctggact ggagaagccc tgcaccattt aaaaaagaag aagtagttta
    12541 gagttttata ttttttgtaa tgttaatata aatttgctat aataggacca tggaagaaga
    12601 acaattatta aaatcaggag agcgcattaa ccagctcttt tcgacagata tcaaaatcat
    12661 tcaaaataga gaggttttta gctattcggt ggatagtgtt ctcttatcac gatttccacg
    12721 ttttcctaag aaggggttga ttgtggattt ctgtgctggg aatggagcag tggggctttt
    12781 tgctagcact cgtactcaag cacagatatt gtctgttgag attcaggagc gtttggcgga
    12841 tatggctgaa cgctctgtcc gtttgaatgg attagaggag caaatgcagg tcatctgcga
    12901 tgatttgaaa aatatgcctg ctcacattca ggggagtaag gtggatatga ttttgtgtaa
    12961 tccaccctat ttcaaggtgg atccttattc taatctgaac gagagtgaac attatctctt
    13021 ggctcgacac gaaatcacga ctaatttgga agaaatctgt catagtgccc agagtattct
    13081 caagtctaat gggcgtttgg ccatggttca tcgtcctgat cgacttctgg atattttgga
    13141 tacgttaaaa cgacataatc tagcccctaa gcgcctgcag tttgtttatc caaaaagaga
    13201 aaaggaagcc aatatgcttt tgattgaggc gatcaaggat ggctcaacaa gtggctttaa
    13261 ggtcttacct cctttgattg tccacaatga tgatggctct tatacgcccg aaatcgaaga
    13321 gatttattat ggatcataag gcttatatgt acgttctgga gtgtcgtgat ggatcctact
    13381 atataggcta tacgactgat atgagaagac gcctcgctat ccacaatagt gggaagggag
    13441 ccaaatatac acgagcacgc ttgccagtca aacttatcta tgctcaaggt tttgccagta
    13501 aggaagaagc catgtcggct gaagctcttt tcaagcgtaa gaagaggcca cagaaggaag
    13561 aatttttatc tgaaaatcaa gatagaaatt tactcagtta ttttgaagaa tcgtggggag
    13621 tcctttgact cctcttacct ttgtcaaaaa gcgaaaaaaa tgctacaata aagaaaataa
    13681 acaaaatgag gtattatcat gtccaagatt ctagtatttg gtcaccaaaa tccagactca
    13741 gatgccatcg ggtcatctgt agcttttgcc taccttgcaa aagaagctta cggtttggat
    13801 acggaagctg ttgcccttgg aactccaaat gaagaaacag cctttgtctt gaactatttt
    13861 ggtgtggaag caccacgtgt tatcacttct gccaaagcag agggggcaga gcaagttatc
    13921 ttgactgacc acaatgaatt ccaacaatct gtatcagata tcgctgaagt agaagtttac
    13981 ggtgttgtag accaccaccg tgtggctaac tttgaaactg caagcccact ttacatgcgt
    14041 ttggagccag ttggatcagc gtcttcaatc gtttaccgta tgttcaaaga acatggtgta
    14101 gctgtgccta aagagattgc aggtttgatg ctttcaggtt tgatttcaga tacccttctt
    14161 ttgaaatcac caacaacaca cccaacagat aaaatcattg ctcctgaatt ggctgaattg
    14221 gctggtgtaa acttggaaga atatggtttg gcaatgttga aagctggtac caacttggct
    14281 agcaaatctg ctgaagaatt gattgacatc gatgctaaga cttttgaact caacggaaat
    14341 aatgtccgtg ttgcccaagt gaacacagtt gacatcgctg aagttttgga acgccaagca
    14401 gaaattgaag ctgcaatgca agctgccaac gaatcaaacg gctactctga ctttgtcttg
    14461 atgattacag atatcgtcaa ctcaaactca gaaatattgg ctcttggtgc caatatggac
    14521 aaggtcgaag cggctttcaa tttcaaactt gaaaacaatc atgccttcct tgctggtgcc
    14581 gtttcacgta agaaacaagt ggtacctcaa ttaactgaaa gctttaatgc gtaagatttt
    14641 gggtgtcagc tcaaaatcgg aaagtctagt ttgccttata tcgaaaggag tttcggctcc
    14701 tttttttcta ggagtgaagt atgttagaaa atggcgattt gatttttgtg agagatgggt
    14761 cagacatggg acaggccatc cagacttcca caggtaacta tagccatgtt gccatttatt
    14821 tggatgggat gatttatcat gctagtggac aggctggtgc tgtctgtcaa gaaccggcag
    14881 acttctttga gtccaatcat ttgtacgacc tctatgttta cccagaaatg gatatccagt
    14941 cggtgaagga aagagcttgc agacatcttg gagcacccta caatgcttct ttctatccag
    15001 atgcagctgg tttctactgc tcccagtata tagcagaaat cctacctatt tttgaaacta
    15061 ttcctatgaa atttggagat ggggaacagg agattagtga tttttggagg gagtattaca
    15121 tagaactagg tctgcctgtt cctctgaacc aagctgggac caatcctagt cagttggcag
    15181 catcgcctct gttacaatgt aaagaaagga atcttcatga ttcagatttt taattcatct
    15241 cgtttgacga gacagccatt tttggagaat tgatccgcta tctggaccag tatgaggatg
    15301 tgattctacg ggaaattaag gctcaatttc cagatgttgc agttgataaa ctcatggaag
    15361 agtatataaa ggcaagcttg attctacgtg aaaataagcg ctattacctc aattttccta
    15421 cgcttgaatc acttgatagt cttgaactgg atcaagagat ttttgtcaga gaagctagtc
    15481 cggtctatca agccttgttg gagcagagtt ttgagacgga attgcgcaat caaatcaatg
    15541 cagctatttt agttgaaaga cggactttgc gcgcattaaa atgaccctgt ccaattattt
    15601 ttacaaggtc aaacagcagt atcctttgac agaaaaacag caggagctct atgacatttt
    15661 aggagatgtt aatcctgagt atgcactcaa gtatatgacg gcttttttgt tgaaatttct
    15721 caaaaaagac cagcttatgc agaaatgccg tgatatcttt gtggacagtt tggttgtctt
    15781 aggctatatt gtgcaaaatg aagatagaaa gtatgagttg gctatcgatt ttgataagga
    15841 gagattaact ttctacttag cgtgatttct tgtttctgag cacattgttt gactttcctt
    15901 agtattcggt ataaactata tgtaaccggt aacacatatc ggaataaact aaaggagaca
    15961 atcatatgtc acttgaaaac aaattggaac aagcaacagg cgctgtcaaa gaaggttttg
    16021 gtaaagttac tggagacagc aagacagaac ttgaaggagc tgttgaaaaa acagttgcta
    16081 aggcaaaaga cgttgtagaa gacgcaaaag gtgctgtaga aggtgccgtt gaaggtttga
    16141 aaaacgtttt tactaaataa taggaaaaaa tcaagggttt cattttccct tgattttttc
    16201 tattcttata aataattttc tgcgacggct gtatctcctg ggtaggattc tttcttgccc
    16261 tggatgattt ggtaacaatc ggctccctta cccgcaataa taactgcatc taattcgtga
    16321 tttgtgatag ccattgccgc cttgatggct tcttggcgat ccgcaatctt ttcaacagga
    16381 tgattgatgt agctactaat ttcatctgca atggccattg ggtcttcata gttagggtca
    16441 tcagcagtca gaaagacttg aatctcaggg tgttgattga ggaggaggcc aaagtcctta
    16501 cgacgacttt ctcccttgtt tcctgttgat cccagaacca gagcaatctt tccggtttga
    16561 tgagtttcaa ccacattgat gagttttttc agactatccc cattgtgggc atagtcgatg
    16621 aagaccttgg ctccattttt ctgagtgagg acttccatac gaccaggaac gcgggttgca
    16681 gcgatgcctt ttttgatgtc ctcaagactt gctccgagac ggagacaagc aagtccagca
    16741 gcaactgcat tttcttggtt gaagttgcca atgagttgga tatcataatc tccagcgagt
    16801 ttacccgtag ctgaaaagct aaaggctttg gaattctcga tttggttatc aaattggcta
    16861 ccatagaaat catggtcttg atcttcaacc tgttctttca agactgagaa gtggtccatg
    16921 tcactgttaa tgatgactgc tcggctattt tccatcaaga gacgcttgtg gtagaaatag
    16981 tcttcaaagc tagggtgttc aatcgggccg atatggtcag gagtgatgtt aagaaagact
    17041 cctacatcaa aggtcagtcc atagactcga tggactagat aggcttgact ggagacttcc
    17101 atgatgaggt gggtacggtc attttgcaca gcctgattca tcatgtcaaa gaggtcaata
    17161 ctctcagggg ttgtcaacgc tgacttaaag aaagtctcgc catcaagagt tgtgttcatg
    17221 gtcgacaaca tagcaggtct atgcccttga gataagatgt tataggcgaa ataggttgct
    17281 gttgtcttac ccttagtacc agtaaaggca aggagtttga gtttctcttg tggattacca
    17341 tagaactcca tggcaatcaa actcatggct ttctttatat cgttcacaat gatgacaggg
    17401 atatcgactt cgtagtcctt ttcagctaca taccaagcta aaccttgtgt tatagcagaa
    17461 agaaggtatt cttttttaaa ggcagcgcct tttgcaaaaa aaagagtgtc ttctgttact
    17521 tttcggctgt cgtagctgat gctatcaaaa ataactttgc tgtagttgta gtggtaatga
    17581 ccttggtcaa taatttcgcg aaaaaggcca tctttcttta aaatatctaa tacggtttca
    17641 atcttaatca tactttctat tgtaaaccga aagtcgtaaa tttacaagta acaaggaaaa
    17701 gtttataatg gaagataagg agtttttcct agttatcaaa attgaatgag gaatctatgt
    17761 cgcacgaaaa caatcaccag caggcccaga tgttacgggg gactgcttgg ctaacggcta
    17821 gtaactttat cagtcgccta ctcggggctg tttacattat cccttggtac atctggatgg
    17881 gggcttatgc agctaaggca aatggtctct ttaccatggg ttacaatatc tatgcttggt
    17941 tcttgttggt ttcaacagcg gggattccag ttgcggtggc caagcaagtt gccaagtata
    18001 ataccatgcg agaagaagag catagctttg ccctgattcg gagcttctta ggctttatga
    18061 caggactagg cctggttttt gctttagtct tgtatgtctt tgctccttgg ctagcagact
    18121 tgtctggcgt gggcaaagac ttgatcccaa tcatgcaaag cttggcttgg ggagtcttga
    18181 ttttcccgtc tatgagtgtt atccgaggat ttttccaagg gatgaataac ctcaaaccct
    18241 atgccatgag ccaaattgct gagcaggtca ttcgtgttat ctggatgctc ctagcaacct
    18301 ttatcattat gaagctcggt tcaggagatt atctagcagc cgttacccaa tcaacctttg
    18361 ctgcctttgt cggtatggta gccagttttg cagtcttgat ttatttcctt gcccaagaag
    18421 gttcactcaa aagagtcttt gaaacaggag ataagattaa cagtaagcgt ctcttggttg
    18481 ataccattaa ggaagccatt ccttttatcc tgacagggtc tgccatccag ctcttccaga
    18541 ttttggatca gctgaccttt atcaatagta tgagctggtt taccaactac agcaatgagg
    18601 acttggttgt catgttttct tatttctcag ccaatcctaa taaaatcacg atgattttga
    18661 tttctgtagg ggtttcgatt gggagtgttg gtttgccact tttgacggaa aactatgtca
    18721 agggggactt gaaagcagct tctcgtctcg ttcaggacag tctcacccta ctctttatgt
    18781 tcttgctacc agcaacggtt ggagtggtta tggtaggaga acctctttat acggtcttct
    18841 atggtaagcc agatagtttg gctctgggct tatttgtctt tgcagttttg cagtctatta
    18901 ttttaggctt gtacatggtc ttgtctccaa tgcttcaggc catgttccgc aaccgcaagg
    18961 ccgttctcta ttttatctat ggttctattg ccaagctagt cttgcaacta cctaccatcg
    19021 ccctcttcca cagttatggt cctttgattt caacaaccat tgctctcatc attcctaacg
    19081 tcttgatgta tcgggatatt tgtaaagtaa ctggtgtcaa gcgcaaggtg attttgaagc
    19141 gaaccatttt aatcagtttg ctgaccctag tcatgtttct gttaatagga accatccagt
    19201 ggctgttagg atttttcttc caaccaagtg gacgtttgtg gagcttcttt tatgtagctc
    19261 ttgtcggtgc catggggggt ggactttata tggttatgag tctgcgtacc tatttattag
    19321 ataaggtaat aggaaaagcc caagcagatc gcctgcgagc aaaatttaag ctttcgtaag
    19381 gtagcattta taaataaaag gaataagttg aacaatcttt taggagaact tgaagcttat
    19441 tcctttttta gcgtaaaaat agctaaaatt atatttcaaa aatagaaaat gaggcttttt
    19501 tcgatttttt ggaaaaaatc attgactaaa caaactaaac gttgtataat aaaacaaata
    19561 tttaaagcag gaggttccgg aaatgaaaaa gtctaagagc aaatatctaa ccttggcagg
    19621 tcttgtcctg ggtacaggag ttttattgag cgcgtgtgga aattctagca cggcgtcaaa
    19681 aacatacaac tatgtttatt caagtgatcc atctagcttg aactatctag cagaaaaccg
    19741 cgcagcaaca tccgatattg ttgcaaattt ggtagacggg ttattagaaa atgaccaata
    19801 tgggaatatt attccatcat tagcagagga ttggactgtt tctcaggacg gtttgaccta
    19861 tacctacaaa cttcgtaagg atgccaagtg gtttacttct gagggagaag aatatgcgcc
    19921 tgtaactgcc caggattttg tgacaggttt gcaatatgca gctgataaaa aatcagaagc
    19981 cttgtatcta gtgcaggact ctgttgctgg tttggatgac tatatcactg gtaaaacaag
    20041 cgacttttca actgtcggtg tcaaggcact tgatgaccaa acggttcaat atactttggt
    20101 taaaccagaa ctttactgga attcaaaaac acttgcaacg atactttttc ctgttaatgc
    20161 agatttcctg aaatcaaaag gggatgattt tgggaaggcg gatccatcta gtattttgta
    20221 caatggacct ttcttgatga aagcacttgt ctcaaaatct gctattgaat ataagaaaaa
    20281 ccctaattac tgggatgcta agaatgtctt tgtagacgat gtgaaattga cctactatga
    20341 tggtagcgac caagaatcac tggaacgtaa ttttacagct ggtgcttata ctacggctcg
    20401 tctttttcct aacagctcca gctatgaagg gattaaagaa aaatacaaaa acaatatcat
    20461 ctatagtatg caaaattcaa cttcatattt ctttaatttt aacctagata ggaagtctta
    20521 caattatact tctaaaacaa gtgacattga aaagaaatcg actcaggaag cagttctcaa
    20581 taaaaacttc cgtcaggcta tcaattttgc ttttgacaga acatcttatg gggctcagtc
    20641 tgaagggaaa gaaggtgcaa caaagatttt gcgtaaccta gtggttcctc caaactttgt
    20701 cagtatcaag ggaaaagact ttggtgaagt tgtagcctct aagatggtca actatggtaa
    20761 ggaatggcaa ggtatcaact ttgcggatgg tcaagaccct tactacaatc ctgagaaagc
    20821 caaggctaag tttgcggaag ctaagaaaga actcgaagca aagggtgttc aattcccaat
    20881 ccacttggat aagactgtgg aagtaacaga taaagtaggc atacaaggag ttagttctat
    20941 caaacaatca attgaatctg ttttaggttc tgataatgta gtgattgaca ttcagcaatt
    21001 aacatcagat gagtttgaca gttcaggcta ctttgctcaa acagctgctc agaaagacta
    21061 tgatttatat catggcggtt ggggacctga ttatcaagac ccgtcaacct atctcgatat
    21121 ttttaatact aatagtggag gatttctgca aaatcttgga ctagagcctg gtgaggccaa
    21181 tgacaaggct aaggcagttg gactggatgt ctatactcaa atgttggaag aagctaataa
    21241 agagcaagat ccagccaaac gttatgagaa atatgctgat attcaagctt ggttgattga
    21301 tagttcttta gttcttccaa gtgtttcgcg tgggggaaca ccatcattga gaagaaccgt
    21361 accatttgct actgcctatg gtttaaccgg tacaaaaggg gttgaatcat ataaatacct
    21421 caaagtacaa gataagattg tcacaacaga cgaatatgca aaagccagag aaaaatggtt
    21481 gaaagaaaaa gaagaatcca ataaaaaagc ccaagaagaa ttggcaaaac atgtcaaata
    21541 aaatctaatt gtagataagt ttgtgtaaga agtctttgtg cttaaaaacg cataatatca
    21601 ggtatataaa atcctagatg ttatgcgttt tgttatagga agatttatta gattttatcc
    21661 tcaaattgag ttattcccga ctttatccgt tgaaatatta taaggagtat ttatgaaatt
    21721 aaaattatta agagtagata ctaaggtgat tatggggagt ttcttacttg ttctgtctag
    21781 tctacttgct ttgttgcttc cccttatctt aaagggttta atagatggga gttctattga
    21841 aaatataggt tccaaagtat ttcaatcgtt tttgattttt attggtcaag ccttgttttc
    21901 ttctattggt tactatctgt ttagtcaatc gggtgaaaaa aagatagcaa aaatcaggaa
    21961 aaaagtgata gaggggttga tttatgcaga gaaatccttc tttgataaga gccaaagtgg
    22021 ggagttgact tctgccattg tcaatgacac gagtgtcatt cgtgagtttt taattacgac
    22081 tttcccaaat attattctga gtttagttat ggtacttggt tccattgtag tcttatttag
    22141 tcttgattgg aatctttctc tacttttatt catcactctt ccttgtatga tgtttattat
    22201 cttgctcctt tccaatatca gtgaaaagta tagtcgtcgt ttacaggagg aaatcggatt
    22261 tttaacaggg caattgactg aaaagattca agaacatgaa ttaattaaga ctaaccaagc
    22321 agagaaaagt gtacaggatg ttttggataa ttgtattgaa agggtacaaa acaattcact
    22381 gaaatcagat agggttactt cttttgagac cccgtttgct ctcttattta tctttgcgac
    22441 tatagctgtg atgctaacct atgggggtta tcgggtcagc gcaggatata tatctgtggg
    22501 aaccttggtt tcgtttttga tttacctctt tcaattactt aatcctatta gtaatatagc
    22561 taattttgta actgtttatt ctaggagcaa gggatcttca gttgcactgg agaacttgct
    22621 tgcagttcct aaagaaaaat ttgagtgagg aaaatcggta tcaggacaag ggttgaattt
    22681 taaccatgtc tattttggtt atgatgaaaa tcgacctgtc ttaaaggata ttacttgttc
    22741 aattttcaag gggcaaaaaa ttgcttttgt tggaccatct ggatcaggaa aatcaacgat
    22801 tgtgcgtttg ttagagcggt tttataaacc gctttcagga gatattctaa tggagcaatc
    22861 aagtatatat gattttaact taaaagaatg gagaagtaaa atcgcttagt aactgatgat
    22921 gaattgatga aagtgctaga cttagtatca ctaggtgatg agattcgctc catgaaagag
    22981 ggactagata ctgaagttgg tgaacgcgga cgactcttgt caggggggca aagccaaaga
    23041 cttcaaatag ctagagccta cttaaaagat gctgaaattc ttatatttga tgaagccact
    23101 gctaatcttg atgcggattc tgagtatgcg attatcagta gcctctattc tgtattaaag
    23161 gagaagacgg ttgtgattat agcgcatcgt ttgtcaacgg taaaagatgt ggattgtatt
    23221 ttcttcttag aggaggggaa aatcactggc tcaggaactc ataaggaact actggaaaat
    23281 catgagcgtt atgctcgttt tgtgcaggag caaatgatag agtgaaggtg tcttttgaga
    23341 ttcaccattt tatagtctat taaagggagc aggaaaaact ccctttttat atagtttgaa
    23401 actataacta gctcttgaaa agaagaaaat gagttgatga aaataagtgg tacaatagtt
    23461 actatagatt tggaggtatt gtatgagcaa ggaattacac attaacacaa ttttggccca
    23521 ggcgggtatt aagtcagatg aagcgacagg tgcattggtg acaccgcttc atttttcaac
    23581 gacctatcag catccagagt ttggtcgatc tactgggttt gactatacgc gcactaaaaa
    23641 tccaactcgt agtaaggctg aggaagtctt ggcggctatt gagtcagcag actatgccct
    23701 agcgactagc tcagggatgt cagctattgt actggccttt agcgtctttc cagtaggaag
    23761 taaggtcttg gcagtgcgtg atctttacgg tggttctttt cgctggttta accaagtgga
    23821 gcaggaaggt cgtttccatt ttacctatgc caatacagaa gaagagttga ttgccgagtt
    23881 agaaaaggat gtggatgttc tctatatcga aaccccaacc aatcccttga tgttggaatt
    23941 tgatatcgaa aaactagcaa aattggctca tgctaagggt gccaaagtgg tggtggacaa
    24001 taccttctat agccctatct accaacgtcc gattgaagat ggagcagata tcgttctcca
    24061 ttcagcaacc aagtatctag caggccacaa tgatgtcttg gctggagtgg ttgtgaccaa
    24121 tagtttagaa ctatacgaga agctttttta caatctcaat acaacagggg cagtcttgtc
    24181 tccatttgac agctaccagt tgcttcgtgg tctcaagacc ttatctcttc gtatggagcg
    24241 ctcaacagct aacgcccaag aagtggttgc ctttttgaag gattctccag cagttaagga
    24301 agttctctac actggtcgtg gaggcatgat ttcctttaaa gtagccgatg aaacacgcat
    24361 tcctcatatt ttgaacagtc tcaaggtctt ctcttttgcg gaaagtttgg gcggagtgga
    24421 aagtcttatt acttatccaa cgactcaaac tcatgctgat attccagcag aagtacgcca
    24481 ttcttatggt ttgacagatg acctcttgcg tttgtctatt gggattgagg atgctagaga
    24541 tttgattgca gatttgcgcc aagccttaga aggataagac aaagatggga aaatatgatt
    24601 ttacaagcct gcccaaccgt ttagggcacc atacctataa atggaaagaa acagaaacgg
    24661 atagtgaagt tctaccagct tggatagcgg atatggactt tgtggtcttg cctgaaatcc
    24721 gccaagccgt gcaaacttac gcagaccaac tggtttatgg ttatacctat gccagtgaag
    24781 acttaattaa ggaaattcaa aagtgggaag ctacacaata cggttacaac tttgacaaag
    24841 aggctcttgt ctttatcgag ggtgtggtac cagccatctc aacagctatt caaaccttta
    24901 caaaagaagg cgaggcggtt ttaattaaca cgcctgtcta cccacccttt gctcgcagtg
    24961 tcaagttgaa taatcgtaga ttgattacta attccttagt ggaaaaggat ggtctgtttg
    25021 agattgactt tgaccaactt gaaaaggatt tggtggaaga ggaggttaaa ctctatattc
    25081 tttgcaaccc tcacaatcct ggtggacgtg tttgggaaaa agaagtgttg gagaagattg
    25141 gccaactttg ccaaaaacac ggtgttttgt tagtttcgga tgagattcac caagatttga
    25201 ccctctttgg tcacaaacac cagtctttca ataccatcaa tcctgccttc aaaaattttg
    25261 ctatcgtctt gagcagtgcc actaaaacat ttaatattgc tggaacaaaa aattcctatg
    25321 cagtcattga aaatcctaag ttgagactgg ctttccagaa acgcctgttg gccaataatc
    25381 agcatgaaat ttcaggcttg ggttatttgg cgacagaagc tgcctatcga tacggtaaag
    25441 attggctaga ggaactcaag caagtctttg aagaccacat caattatgtg gtggatctat
    25501 ttggaaaaga gactaaaatc aaggtcatga aaccgcaagg tacctacttg atttggcttg
    25561 acttttcagc ctatgacctg actgatgaaa cattgcaaga gttgttgaga aatgaagcca
    25621 aggttatcct caaccgtggt ttggattttg gagaggaagg aagtctccat gcccgcatca
    25681 atatagctat gcccaaatct ctgttgcaag aagtctgtca gcggattgtg gctacttttg
    25741 ccaaacgtta aaaatccagc cttctaggag aaaagtcttc ctagaaggct attttcatag
    25801 gcgaaaatat ggtataataa aaagataagg taaaggtgaa aatatggcta aattgattcc
    25861 ggggaaaatt cgtatcgaag gtgttgccct ttatgaaact ggtaaggttg atatcatcaa
    25921 ggaaaagaac aatcggctct acgctcgcgt tgcagaagaa gaactgcgct atagtttaga
    25981 ggatgatttg gttttttgtg cctgtgattc ttttcaaaag aggggctact gtgtgcattt
    26041 ggcagcgcta gagcattttc tgaaaaatga tgagcgtggt caggaaatct tgtggagtct
    26101 ggaagaaggt catgaagaaa aagaggccgt tgaaaccaag gtgaccttgg gtggcaagtt
    26161 tttgaatcga attttatctc caaaatcaga atgcgcctat gagttatcag ctgtgggtca
    26221 ggtggaagca ggaaccaatc atatcttgtg gactctgaga atcggccaaa tcaatagcca
    26281 aaaatactat gtcattcggg atattccact ttttttaagg attgtcgagc agagaaagtc
    26341 gtatatgatt ggcaagattt atgaggagtc tctttcttgg gaagcctttg atgatgccag
    26401 ccaagaactt ttgactttct tgcacggact aacggaggaa gggctggttc cagacctctt
    26461 tttccaaaac caaggtcggc acctcttttt ccctctgacc ttttttgagc agggtgtgaa
    26521 tttactgatg gccttgcccc attttcaatt tgaccatcaa gtggatagct accaaaccct
    26581 gctttttcag gatatgcatg ctgatgccaa tctatttgcc tttacagtaa cagaatactc
    26641 ggactatttt gaaatggaaa tcagtgagag tcctagggtc aatgtctttt atcagggagc
    26701 agtacttttc cataaaggtc aggtttattt tttaacagac cagcagatgc gtcttctcaa
    26761 ggaaattaaa gcgttacctg tgggtcaaca aggaaagaaa tacctgcaat ttgatagcag
    26821 tgatcgagac aaattggcct cctgtctgac tctttttatc cagatgggca ccgtttcagc
    26881 tccagaacgt ctacaaatca aaacttttgc gccctctttt tactttgaca gggaagaaga
    26941 taatcggatt cgtttagaaa ttcagtttga ttatggaaat agacaggtat ctagccgaca
    27001 agagctagaa gaattaccat tttcaagtga cgcggactta gaagaaagaa ttttccaagt
    27061 ctgtttggct gcgggctttg aagccgattt tcaatcttgg cgtcaggcct taaaagcgga
    27121 gtctgtctat catttttttc atgatatcat tccagtcttt gaaaaactcg ggcatgttga
    27181 cctatcagat aaactagaag agctttatag cctagcgagt cctcaggtgc agattgcctc
    27241 caagggaggt ctcttggaaa tccagtttga ttttcaaaat attgcccagg aggaaatcga
    27301 ccaagccatg caggccttgg ttgccaatca ggatttttat attgattcgt ctaatcaagt
    27361 ttactttttc gatgaagaaa ccaagaaaat tcgccaaaat ctacaggaac tggggcaatt
    27421 tgaattaaaa gatgggacct tgcaggctcg gaaatccttg gcctacagtt tagctcatct
    27481 ctttgaaggg cgagaccgtg tttctttttc acaagaattc cagaatctgg cccaggattt
    27541 gacgcatcca gaggactttc ctttgcaagc aactcaggtc aaggctgact tgcgagatta
    27601 tcaggaaaag ggaattggct ggttgcagat gctccatcat tatggttttg gtgggatttt
    27661 ggctgatgat atgggacttg ggaaaaccct tcagaccatt gcttttttga ctagtcaagt
    27721 gacaaaagaa agtcgagtct tgattctcgc tccgtcgggt ttgatttaca actgggcgga
    27781 tgagtttcag aaatttgccc cacagttgga tgtggctgtt gttcatggtt tgaaagcaag
    27841 tcgtgaggag attcttgccg agagccatca aatctatgtg actagctatg ccaccttccg
    27901 tcaggacagt gagttttatc aggggatggc ctttgacttc cttttcttag atgaggctca
    27961 ggtcatgaaa aatgcccaga ccaagattgc ccagaccttg agacaatttg tggtgccgtc
    28021 ggtctttgcc ttgtcaggaa ctccgattga aaaccatctg ggtgagttgt ggtctatttt
    28081 ccaaatcgtc atgcccggac ttttgccaag caagaaagaa tttatgaaat tgccagcaga
    28141 gcgagtggct cagtttatca agcctttcgt gatgcgacgc aagaaagaag aagttctgac
    28201 tgaattgcca gacttgattg aggtggttta taaaaatgaa ctggaagacc agcaaaaggc
    28261 tatttacctt gcccagttac aacagatgcg agaccatctg gctcaagtgt cagaacagga
    28321 atttcagcga agtcgtgtgg aaattttatc tggtttgatg cgcttgcgtc aaatatgtga
    28381 cactcctgcc ctgtttatgg aagattatca gggagccagc ggcaaactag atagtctccg
    28441 agacctactg gtacaggtgg cagacggcgg acaccgtgtc ttgattttct ctcagttcaa
    28501 gggaatgttg gaaaaaattg aacaagaact gccagacttg ggcctgactt cctttaaaat
    28561 tacgggttca accccagcca aggaaagaca agacatgacc aaggccttta atcaaggaga
    28621 aagagatgcc tttctgattt ccctcaaggc tggtggggtc ggtctgaacc tgacaggtgc
    28681 agatacagtg atcttggttg acctttggtg gaatcctgcg gtggaagcgc aagccattgg
    28741 ccgtgcccat cggatgggtc aggaagaaac ggttgaggtc tatcgcttgg tgaccaaggg
    28801 aaccattgaa gaaaaaattc aggaactcca agaacaaaag aaacatctgg tgtcacaagt
    28861 attggacggc acagagtcac gtggtagtct gaccctagca gaaattagag aaattttggg
    28921 aatttctgaa gccagcactt gaaaaatcaa gacaatacgc tataatgaag tgttgaaagg
    28981 aaatagaaaa tgaaacaaga acgatttcca ttggtgtcag atgacgaggt catgttgact
    29041 gaaatgccag tcatgaatct ctatgatgag tctgatctga tcagtaatat caagggtgag
    29101 tatcgagata aaaattattt agaatgggct cctattgctg aagaaaaacc agtaaaaccg
    29161 attgaaaagc aagtagggaa acctaaaaaa gctcctttag gggttaaaaa agaaggaaag
    29221 agctatgcgg aggtggcgcg tgaagaagcg cgtgcagact tgaaaaagaa acgctctgct
    29281 aactatctaa ctcaggattt cagccttgcg agacgtcatt ctcagcccag tctagttaga
    29341 cagggcaatc aaccgacaac tcctttccaa aaggaaaatc ctggtgaatt tgtcaaatat
    29401 agccaaaaat tgacccagtc tcattatatc ttggcggaag aagttcattc tatccctacc
    29461 aagaatgaag aagtgtcagc acctgctcca aagaaaaaca attatgattt tctaaagaag
    29521 agccaaatct acaataaaaa aagtaaacaa acagaacaag aacgtcgggt tgcccaagag
    29581 ttgaatctga ccagaatgac agaataggga gaaaacatgt caaagacata tcattttatc
    29641 ggaattaagg gatcagggat gagtgccttg gccttgatgt tgcaccagat ggggcacaag
    29701 gttcagggat cagatgttga aaagtactac tttacccaac gcggtcttga gcaggcagga
    29761 attaccattc ttccttttga tgaaaagaat ctagacggtg atatggaaat tatcgctgga
    29821 aatgcctttc gtccagataa caacgtcgaa attgcctatg cggaccaaaa tggtatcagc
    29881 tacaaacgtt accatgagtt tctaggtagc tttatgcgtg actttgttag catgggagta
    29941 gcaggagcac atggaaaaac ttcaacgaca ggtatgttgt ctcatgtctt gtctcacatt
    30001 acagatacca gcttcttgat tggagatggg acaggtcgtg gttcggccaa tgccaaatat
    30061 tttgtctttg aatctgacga atatgagcgt cacttcatgc cttaccaccc agaatactct
    30121 attatcacca acattgactt tgaccatcca gattatttca caagtctcga ggatgttttc
    30181 aatgccttta acgactatgc caaacaaatc accaagggtc tttttgtcta tggtgaagat
    30241 gctgaattgc gtaagattac gtctgatgca ccaatttatt attatggttt tgaagctgaa
    30301 ggcaatgact ttgtagctag tgatcttctt cgttcaacaa ctggttcaac cttcaccgtt
    30361 catttccgtg gacaaaactt ggggcaattc cacattccaa cctttggtcg tcacaatatc
    30421 atgaatgcga cagccgttat tggtcttctt tacacagcag gatttgattt gaacttggtg
    30481 cgtgagcact tgaaaacatt ttccggtgtt aaacgtcgtt tcactgagaa aattgtcaat
    30541 gatacagtga ttatcgatga ctttgcccat catccaacag aaattattgc gaccttggat
    30601 gcggctcgtc agaaataccc aagcaaggaa attgtagcag tctttcaacc gcataccttt
    30661 acaagaacca ttgccttgtt ggacgacttt gcccatgctt taaaccaagc agatgctgtt
    30721 tatctagcgc aaatttatgg ctcggctcgt gaagtagatc atggtgacgt taaggtagaa
    30781 gacctagcca acaaaatcaa caaaaaacac caagtgatta ctgttgaaaa tgtttctccg
    30841 ctcctagacc atgacaatgc tgtttacgtc tttatgggag caggagacat ccaaacctat
    30901 gaatactcat ttgagcgtct cttgtctaac ttgacaagca atgttcaata ggatgttccc
    30961 atggaaattc caattaagat cattcaggca agcaagtctg atttgcctga gataggggca
    31021 cttcagacct cgtcttttcc agctgaaaag cagcaacttt cccatatttt agaagaaagt
    31081 atccgtaagt gtgcggatac ctttcttcta gctagggatg aaaatcaact tttaggctat
    31141 attttatcaa gtccccagtc agacaatccg caatatctaa aagtacattc tttagtcatc
    31201 gagtctgacc atcagagaca gggcttggga acacttcttc ttgcagcctt gaaagaggtg
    31261 gcagttgatc tggattacaa agggattcgt ttggagagtc ctgatgagct gctttcctat
    31321 tttgaaatga acggttttgt tgatgaagaa gcaactttgc tctatgcaac tagccagggc
    31381 tatagtatga tttggtttaa tcccttttat ctggaggaac aatgaaaatc agacaagcaa
    31441 gattagaaga tttggatcgg attgttgaac ttgaatttga aaatttttcg gtcgaagaag
    31501 ccattcctcc ttctgtcttt gaagcacatt tgagagaaat tcagacctct tttctggttg
    31561 ctgaaaaaga aggaagaatc atgggttata tcgaaggacc agttggcctg caccgccatc
    31621 tgcaagacca gtcttttaca gaagaaataa aagactatag tcatgagcct ggtggttata
    31681 tctctgtgac ctgtctgtct attgccaagg aggcacaggg actcggactg ggtcagaaat
    31741 tgctgacagc tttgaaagaa gttgctcttg aagatgagag agatggcatt aatctaacct
    31801 gtcatgacta tctcatcgcc tattatgaaa aacatggatt tgtcaacgaa ggccagtccc
    31861 agtcaacctt tgcaggggaa acatggtatg atatggtctg ggaaatgaaa aaataagtta
    31921 ggaaaagtat catagattgc tttttttgga cttttaagat ataatattat ggattatcaa
    31981 caaggaggaa aaacttttga gtgaaaagtc aagagaagaa gagaaattaa gctttaaaga
    32041 gcagattctg agagatttag aaaaagtaaa aggctatgat gaagttctga aagaagatga
    32101 ggcagtagtt cgcactcctg caaatgaacc ttcagctgaa gaactcatga ctgattcctt
    32161 gtcaacggta gaggagatta tgagaaaagc tcctaccgtg cctactcacc caagtcaagg
    32221 tgtaccagct tctccagcag atgagattca aagagaaact cctggtgttc caagtcatcc
    32281 aagtcaagat gtaccttctt ctccagcgga agaaagtgga tcaagaccag gtcctgttag
    32341 acctaagaaa cttgaaagag aatacaatga aaccccaaca agggtagctg tttcctatac
    32401 gacggcagag aaaaaagcag aacaagcagg tccagaaaca cctacgcctg ctacagaaac
    32461 agtggatatc atcagcgata catcacgtcg tagccgtaga gaaggagcaa aacccgttaa
    32521 tcctaagaaa gagaagaagt cacatgtgaa agcttttgtg atttcattcc ttgtattcct
    32581 tgccttgctc tcagcaggtg gttactttgg ttaccagtac gtgctagatt ctttgttacc
    32641 tatcgatgct aattctaaga aatatgtgac ggttggaatt ccagaaggtt caaacgttca
    32701 agaaatcggt acgacgcttg aaaaagctgg tttggtaaag catggtctga tttttagttt
    32761 ttatgccaag tataaaaatt ataccgactt gaaagcaggt tactacaatt tgcaaaagag
    32821 tatgagtaca gaagacttac tcaaagagtt gcaaaaaggt ggaacagatg aaccgcaaga
    32881 acctgtactt gcgactttga caattccaga aggttatacc ttggatcaga ttgctcaagc
    32941 tgtgggtcaa ttgcaaggtg acttcaaaga gtctttgaca gcggaggctt tcttggctaa
    33001 agttcaagat gagacgttta tcagtcaagc agtagcgaaa tatcctactt tactggaaag
    33061 tttgcctgta aaagacagcg gtgcgcgtta tcgtttggaa ggataccttt tcccagctac
    33121 atactctatc aaggaaagca caactattga gagcttgatt gatgagatgt tagctgctat
    33181 ggataagaac ctatctcctt actatagtac tatcaaatct aaaaatttga ctgtcaatga
    33241 gttgttgacc attgcttcct tggtcgaaaa agaaggtgcc aagacagaag atcgtaagct
    33301 cattgcaggt gtattctaca atcgtttaaa tcgtgatatg ccacttcaaa gtaatattgc
    33361 aatcttgtat gcccaaggaa aactggggca aaatatcagt ctagctgagg atgttgcgat
    33421 tgataccaac attgattcac cttataatgt ttataaaaat gtaggtctca tgcctggtcc
    33481 agtcgatagt ccaagtctgg atgcgattga gtcaagcatc aatcaaacta agagcgataa
    33541 cctctacttt gtagcagatg tcacagaagg caaggtctac tatgctaaca atcaagaaga
    33601 ccacgaccgc aatgtcgctg aacatgtcaa cagcaaatta aactaaacaa actaaaatta
    33661 tgtgatacgt cacataattt tctttagaaa atattatcag aagaaagttg agaaaaatgg
    33721 cagaaaaaac atatcctatg acccttgagg aaaaggaaaa acttgaaaaa gaattagaag
    33781 aattgaaatt ggttcgtcga ccagaagtgg tagaacgcat taagattgcc cgttcatacg
    33841 gtgacctttc agaaaacagt gagtacgaag cagctaagga tgaacaagcc tttgtcgaag
    33901 gacaaatctc tagcttagaa acaaaaatcc gctatgctga aatcgtcaat agcgacgcag
    33961 ttgcccagga cgaagtagcg attggtaaaa cagtcaccat ccaagaaatt ggtgaggacg
    34021 aagaagaagt ttatattatc gtaggttcag ctggtgcgga tgcctttgca ggtaaggttt
    34081 caaatgaaag cccaattggg caggccttga ttggcaagaa aacaggtgac acagcaacca
    34141 ttgaaacgcc tgttggtagc tatgatgtaa aaatcttgaa ggttgaaaaa acagcctaaa
    34201 aacagaaaaa ggagtgggga ggcgatgtgc ttcactcact cctttttcca ttttgctatt
    34261 cttcgaaaat ctcttcaaac cacgtcagcg tcgccttgcc gtatgtatgg ttactgactt
    34321 tgtcagtttc atctacaacc tcaaaac
//
LOCUS       DAVBEM010000020        33324 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVBEM010000020 DAVBEM010000000
VERSION     DAVBEM010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33324
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.020"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            <1..327
                     /locus_tag="VQ548_000975"
     CDS             <1..327
                     /locus_tag="VQ548_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET2653842.1"
                     /translation="KPQTEKPEEETPREEKPQSEKPESPKPTEEPEEESPEESEEPQV
                     ETEKVEEKMREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAEKLLA
                     LLKESK"
     gene            749..979
                     /locus_tag="VQ548_000976"
     CDS             749..979
                     /locus_tag="VQ548_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HET2653843.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAIKC"
     gene            1383..2096
                     /locus_tag="VQ548_000977"
     CDS             1383..2096
                     /locus_tag="VQ548_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HET2653844.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2154..2756
                     /locus_tag="VQ548_000978"
     CDS             2154..2756
                     /locus_tag="VQ548_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653845.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSNFDDFLEKNYLKTIWQ
                     VSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            2892..3545
                     /locus_tag="VQ548_000979"
     CDS             2892..3545
                     /locus_tag="VQ548_000979"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HET2653846.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            3555..4019
                     /locus_tag="VQ548_000980"
     CDS             3555..4019
                     /locus_tag="VQ548_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET2653847.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4032..5300
                     /locus_tag="VQ548_000981"
     CDS             4032..5300
                     /locus_tag="VQ548_000981"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HET2653848.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5314..5574
                     /locus_tag="VQ548_000982"
     CDS             5314..5574
                     /locus_tag="VQ548_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653849.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5585..6946
                     /gene="pdrM"
                     /locus_tag="VQ548_000983"
     CDS             5585..6946
                     /gene="pdrM"
                     /locus_tag="VQ548_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HET2653850.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            7100..8068
                     /locus_tag="VQ548_000984"
     CDS             7100..8068
                     /locus_tag="VQ548_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HET2653851.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8084..9076
                     /locus_tag="VQ548_000985"
     CDS             8084..9076
                     /locus_tag="VQ548_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HET2653852.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYISEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            9294..10337
                     /locus_tag="VQ548_000986"
     CDS             9294..10337
                     /locus_tag="VQ548_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HET2653853.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10401..12086
                     /gene="lpdA"
                     /locus_tag="VQ548_000987"
     CDS             10401..12086
                     /gene="lpdA"
                     /locus_tag="VQ548_000987"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HET2653854.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEIIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMQSPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEIIGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            12150..13139
                     /locus_tag="VQ548_000988"
     CDS             12150..13139
                     /locus_tag="VQ548_000988"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HET2653855.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(13206..14276)
                     /gene="xerS"
                     /locus_tag="VQ548_000989"
     CDS             complement(13206..14276)
                     /gene="xerS"
                     /locus_tag="VQ548_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HET2653856.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(14860..16410)
                     /locus_tag="VQ548_000990"
     CDS             complement(14860..16410)
                     /locus_tag="VQ548_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HET2653857.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFIIIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGSLVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(16426..17205)
                     /locus_tag="VQ548_000991"
     CDS             complement(16426..17205)
                     /locus_tag="VQ548_000991"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HET2653858.1"
                     /translation="MATIKEIKELLVTVKELESPIFLDLEKDNRSGVQKEISKHKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQVVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDEFMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(17192..18043)
                     /gene="ylqF"
                     /locus_tag="VQ548_000992"
     CDS             complement(17192..18043)
                     /gene="ylqF"
                     /locus_tag="VQ548_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HET2653859.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EGLDGND"
     gene            complement(18250..18426)
                     /locus_tag="VQ548_000993"
     CDS             complement(18250..18426)
                     /locus_tag="VQ548_000993"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2653860.1"
                     /translation="MQAGIPTDNEVSYALIYQQETLPATGSSTSALTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            complement(18478..24369)
                     /gene="iga"
                     /locus_tag="VQ548_000994"
     CDS             complement(18478..24369)
                     /gene="iga"
                     /locus_tag="VQ548_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin A1 protease"
                     /protein_id="HET2653861.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGSIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKG
                     ETEVQPESPDTVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVK
                     PTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSENTGEVSSNPSDS
                     TTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNS
                     GKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEKKLEL
                     RNVSDIELYSQTNGTYRQHVSLDGIPENTDTYFVKVKSSAFKDVYIPVASITEEKRNG
                     QSVYKITAKAEKLQQELENKYVDNFTFYLDKKAKEENTNFTSFSNLVKAINQNPSGTY
                     HLAASLNANEVELGPDERSYIKDTFTGRLIGEKDGKNYAIYNLKKPLFENLSGATVEK
                     LSLKNVAISGKNDIGSLANEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESS
                     FKGRIVNTYETTDAYNIGGLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLV
                     DQDAHIQNSYAEGDINNVKHFGKVAGVAGYLWDRTSGEEKHAGELTNVLSDVNVTNGN
                     AITGYHYTGMKVANTFSSKANRVFNVTLEKDEVVSKESFEERGTMLDASQIVSKKAEI
                     NPLTLPTVEPLSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKSTIVKYGNLVK
                     ENSLLYQKELLSAVMMKDDQVITDIVSNKQTANKLLLHYNDHSSEKFDLKYQTDFANL
                     AEYNLGNTGLLYTPNQFLYDRDSIVKEVLPELQKLDYQSDAIRKTLGISPEVKLTELY
                     LEDQFSKTKQNLGDSLKKLLSADAGLASDNSVTRGYLVDKIKNNKEALLLGLTYLERW
                     YNFNYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYGISLAS
                     QHGTTDLFSTLEHYRKVFLPNTSNNDWFKSETKAYIVEEKSTIEEVKTKQGLAGTKYS
                     IGVYDRITSATWKYRNMVLPLLTLPERSVFVISTMSSLGFGAYDRYRSSDHKAGKALN
                     DFVEENARETAKRQRDHYDYWYRILDEQSREKLYRTILLYDAYKFGDDTTSGKATAEA
                     KFDSSNPAMKNFFGPVGNKVVHNQHGAYATGDGVYYMSYRMLDKDGAITYTHEMTHDS
                     DQDIYLGGYGRRNGLGPEFFAKGLLQAPDQPSDATITINSILKHSKSDSTEGSRLQVL
                     DPTERFQNAADLQNYVHNMFDLIYMMEYLEGQSIVNKLSVYQKMAALRKIENKYVKDP
                     ADGNEVYATNVVKELTEAEARNLNSFESLIDHNILSAREYQSGDYERNGYYTIKLFAP
                     IYSALSSEKGTPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGK
                     ERGLVTDELVLKKVFDGKYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPSYGTK
                     TINNVDELQALMDQAVLKDAEGPRWSNYDPEIDSAVHKLKRAIFKAYLDQTNDFRSSI
                     FENKK"
     gene            complement(24578..25756)
                     /locus_tag="VQ548_000995"
     CDS             complement(24578..25756)
                     /locus_tag="VQ548_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653862.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCRNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLPLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWILNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            complement(25926..29576)
                     /gene="addA"
                     /locus_tag="VQ548_000996"
     CDS             complement(25926..29576)
                     /gene="addA"
                     /locus_tag="VQ548_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HET2653863.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEICSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWKLAKTFQTFMSHFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALVEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIDEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQIIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(29573..32848)
                     /gene="rexB"
                     /locus_tag="VQ548_000997"
     CDS             complement(29573..32848)
                     /gene="rexB"
                     /locus_tag="VQ548_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HET2653864.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPISPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            complement(33048..33203)
                     /locus_tag="VQ548_000998"
                     /pseudo
     CDS             complement(33048..33203)
                     /locus_tag="VQ548_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
BASE COUNT         9516 a         6538 c         6861 g        10409 t
ORIGIN      
        1 aaacctcaga cagaaaaacc tgaggaagaa acccctcgag aagagaaacc gcaaagcgag
       61 aaaccagagt ctccaaaacc aacagaggaa ccagaagaag aatcaccaga ggaatcagaa
      121 gaacctcagg tcgagactga aaaggttgaa gaaaaaatga gagaggctga agatttactt
      181 ggaaaaatcc aggatccaat tatcaagtcc aatgccaaag agactctcac aggattaaaa
      241 aataatttac tatttggcac ccaggacaac aatactatta tggcagaagc tgaaaaacta
      301 ttggctttat taaaggagag taagtaaagg tagcagcatt ttctaactcc taaaaacagg
      361 ataggagaac gggaaaacga aaaatgagag cagaatgtga gttctagttc tcattttttt
      421 catgaaaatg tgcaaaatat agtagattga aactagaata gtatacctct acttctaaaa
      481 cattgttaga aatcgatttg actgtcctgt tcttatttca ttttactata tcttaacaga
      541 tagtgtaaat aaagataaac tatttactgg ctaattaatc agttaaacac tagttaagga
      601 gtaatgatga aaaaaagaac aatactatta ttgatggcca gtctgttagc tcttgtctta
      661 ggagcatgtg gtttcttgga catattgatc ctggatcatt ctcatcagga ttactcttta
      721 ctgctatttt agaaactggg gtggtttgat ggaaagtatt ggtattggtc ttgttatcgt
      781 ttcacattcc aaacacattg cagaaggtgt tgttgaactg attagtaaag tagctaaaga
      841 tgttccgatt acttatgtag gaggaaccga gggcggagga attggaacga gttttgatca
      901 agtagatagg gttgtttccg aaaatccagc agatacttta cttgcctttt ttgacctagg
      961 ttctgctata aaatgttaag taaatgattt caaaatcaga aagggattgc tttgggcagt
     1021 tcctttttaa tgtaaatgta aaaggagtag aatcatagtg tttctaaatt gtgaatcaat
     1081 caaaactgat tgtgatgggg ctattctagc tttagaatcc ttcaaaaatt aaaatttaag
     1141 gcaatcaatt acttggaaga gtatgaaagc atttagttta taggaattct aggcctagaa
     1201 ttacatatgt atttatgaag ataggggtgt tcgatagtta gtattgttct gttctgaaag
     1261 atttgagctg tcagttgtat agaaagtgtt cgaatttttt ttaagtgatt aaattagtta
     1321 attgtatgag gttctttatg atataatgtt cttaatgaat tttcagaaag gaaaacctca
     1381 aattgttcta caaatttcta ctcttcgacc tcgaccacac tcttcttgat tttgatgctg
     1441 ctgaggatgt ggctttgacc caacttctaa aagaagaagg agttgcggat attcaggctt
     1501 ataaagatta ttacgttcct atgaacaagg ctctctggaa agacttggag ctgaagaaaa
     1561 tcagtaaaca agagctggtt aacacgcgct tttctcgttt atttgctcat tttggacagg
     1621 aaaaagacgg tagttttctt gcccagcgtt accaatttta cctcgcccag cagggacaaa
     1681 cactatcggg cgctcatgat ctcttggaca gcctcattga gcgtgattat aacttgtatg
     1741 ctgcgacaaa tggcattact gccattcaga caggacgttt ggctcaatct ggtctagcac
     1801 cttatttcaa tcaagtcttt atctcagaac agttgcaaac tcaaaagccg gatgctctct
     1861 tttatgaaaa gattggccag caaattgctg gatttagtaa agaaaagacg ctgatgattg
     1921 gagattctct aaccgccgac attcaaggtg gcaataatgc ggggattgat actatctggt
     1981 ataatcctca tcacctcgaa aatcacacac aagcccagcc gacttacgaa gtctattctt
     2041 accaagactt gctggattgt ttagataaaa atattcttga aaagatcaca ttttaaagga
     2101 gacgagctaa tgactacaaa aaagctaata ttactattga agagtacatt gaaatgtctg
     2161 aagttgattt taatgaagct gttaattatg aatttacatc tgacacttgt caattagcaa
     2221 atagtattta tcaatctctt tttaagtttt ttgataagaa aaatttctct ggcgatttaa
     2281 tttttacttg gaaatctcca tcattagtca aagaagggga ttatattggg agaagggatt
     2341 cacaagtaga taatcttaga gtaataggaa atatatttcc gaattatctt actaatcgaa
     2401 aatatagcct caatatgaat cgtaatggct gtatgggaga ttttcctcat gacttttttg
     2461 atatatacct agatcatgta gcaaaatatg cctacgaaca aaaagttaat aatattaaag
     2521 agtattatcc tttaaaaaga gcgattttac accaagagaa tgcattgtat tttcgatttt
     2581 tttctaattt tgacgacttt ttagaaaaaa attatttaaa gactatatgg caagtttcta
     2641 aagaaactcc tttttctgaa atggatttta atatgtttaa aaatatttca gaaaagataa
     2701 tcttcgaaag aggtagtaaa atgcttaatg atttaaaaag taattataaa aaatagccag
     2761 tctttataaa ctgtattcac gtattcaaat cgtatatagt cgatttatta aatctttaga
     2821 taaactgtaa aaagtggttt ccatagccac tttttgctat aatagaggca gtaaaaatga
     2881 aggagtcggc tatggaacac tcgtcttggc atgctttgat taaggcgcaa ttacctgagg
     2941 gttatttcgg gaaaatcaat cagtttatgg agcaggtcta ttctcagggg attatttatc
     3001 cacccaagga aaaggttttt caggctctct tgacaacact gcttgaagaa gttaaggtgg
     3061 taattctagg gcaagacccc tatcacggac caggtcaagc gcagggcttg agtttttctg
     3121 tacctgactc tatcccagct ccaccatcct tgcaaaatat cttgaaagaa ttgtcagatg
     3181 atatcggagt taagaaatct catgatttga cagcttgggc tgagcaagga gtcttgcttc
     3241 ttaatgcttg tttgactgtt cctgctggac aggccaatgg tcatgctggt caaatctggg
     3301 agccttttac tgatgctgtg attcaggtgg tcaatcatct agatagacca gtcgtttttg
     3361 tactctgggg agcttatgca cgtaagaaga aggccttagt taccaatcct catcacttga
     3421 ttatcgaatc agcccatcca agtcctttgt cggtttatag aggattttgg ggttccaagc
     3481 ccttttccaa ggccaatgca ttcttaaaag agacaggaca agagccaatc gattggctta
     3541 gataaggaga aaatatgcct cagttagcga cgatttgcta cattgataat gggaaagaac
     3601 tgctcatgct ccatcgtaat aagaaaccca atgatgtcca tgaagggaaa tggattggtg
     3661 tgggtggtaa gctagagaga ggagagacgc cccaggaatg cgcggcgcgt gaaatccttg
     3721 aagaaacagg gctcaaagcc aagccagttc taaaaggtgt catcactttt cctgaattta
     3781 caccagattt agactggtac acctatgttt ttaaggtgac ggagtttgag ggcgacttga
     3841 ttgactgcaa tgaggggacg ctagaatggg ttccctatga cgaggttttg agcaagccga
     3901 cttgggaagg tgaccacacc tttgttgagt ggcttttaga ggataaaccc ttcttttcag
     3961 ccaagtttgt ttatgatggg gataaattgt tggataccca agttgatttc tatgaataaa
     4021 ggagaaagca gatgctacta atcaaaaatg gtcgtgtaat ggatcctaag tctggtttgg
     4081 atcaagtttg tgatgtctta gttcaagatg ggaaaattat caaaattgcg cctgagatca
     4141 cggaagaagg agcagaaacg attgatgcta ctggtcttgt ggttgctcct ggtttggtcg
     4201 atattcatgt gcatttccgt gaacctggtc aaacacataa agaagacatt catactggtg
     4261 ccctggcagc cgctgcaggt ggttttacta ctgtcgtcat gatggctaat accagtccaa
     4321 ccatttcaga cgtggagact ttgcaagcag ttctccagtc agctgccaaa gagaagatta
     4381 atgtcaagac agttgcgacc attactaaaa actttaatgg taaaaacttg actgacttta
     4441 aggcgctctt agaagctggt gcggttggtt tctctgatga cggtattccg cttgagagca
     4501 gtaagattgt caaggaagcc atggaggaag ccaaaaaact caataccttt atcagccttc
     4561 atgaggaaga tccaggtttg aacggtgttc ttggctttaa tgaaaatatt gctagagaac
     4621 atttccatat ctgcggtgct actggggtgg ctgagtacgc tatgatggcg cgtgatgtca
     4681 tgattgccta tgcaactaaa gcccatgttc acatccagca tttgtctaag gaagaaagtg
     4741 ttaaagtagt ggagtttgct caggggttag gtgcagaagt cacagcagaa gtagcgccac
     4801 agcatttctc taagacagaa gcacttcttt taacacaagg tagcaatgct aagatgaatc
     4861 caccgcttcg tttggaatca gaccgtcgtg ccgttatcga aggtctcaaa tcaggtgtca
     4921 tcacagttat tgcgactgac cacgcgcctc atcatgtaga tgaaaaaaat gttgaggata
     4981 ttaccaaagc gccatctggt atgactggct tagaaacatc cctgtctctc ggcttgacct
     5041 atttagtaga agctggtgag ttgagcttga tggaattact tgaaaaaatg acatacaacc
     5101 cagccaagct ttacaacttt gaagcaggtt acttggctga gaatggtcca gcagatatca
     5161 ctatttttga tgccaaggct gaccgccttg tggactccca ttttgcttcc aaagcagcta
     5221 attcaccatt catcggtgaa accttaaaag ggcaggttaa atataccatc tgtaagggac
     5281 aaatcgtcta tcaagcttga taggagttag aatatgaatt attttcgaaa acgtagggag
     5341 agacaagcga aatctaatag tggaatttac tgtcccgcag ctaatcgttc caaaattcaa
     5401 tatgaaacta aagaaaaagc tgaccatgcg gttcaatatg ataacggagg tttagttaga
     5461 agctattatt gtcgtacatg tgcgtgttgg catactactt caaaatctaa taaacctccg
     5521 ctaagtttga aaaactatgg tctgaaactc tttggtttag ataaatcaga atagaaagag
     5581 aagtatgtat aagacaaagt gtttacgaga gaagttagta ttatttttaa aaattttctt
     5641 cccaatcctg atctaccaat ttgccaatta ttctgcctct tttgttgata ctgcaatgac
     5701 aggtcaatac aacactatgg acttggctgg tgtatctatg gcaaccagta tctggaatcc
     5761 tttctttaca tttctaacag ggattgtgtc agccttggtg cctatcattg gtcaccatct
     5821 tggtcgaggc aaaaaggaag aagttgcgtc tgatttttac caatttattt atttggcctt
     5881 gggcctatct gtggtcttgc tggggatggt acttttcttg gcaccaacaa tcttgaatca
     5941 tattgggtta gaagcagcag tagcggcagt agcggttcgc tatctttggt ttttatctat
     6001 cgggattatc cccttgttgc tctttagcgt cattcgttcc ttgctggatt cgctgggctt
     6061 gaccaaactg tccatgtacc tcatgctttt gttactccct ctcaatagcg gatttaacta
     6121 tctcttgatt tacggtgcct ttggtgttcc agaactggga ggggctggtg ctggtttagg
     6181 aacatccttg gcctactggg tcttgcttgg gatttctgtt ctggttttat ttaaacagga
     6241 gaagctcaaa gccttacacc ttgagaaacg aattccactt aatatggata aaattaagga
     6301 aggagttcgt ttaggtctgc ctattggggg aactgtcttc gcggaagtgg ctatcttttc
     6361 agtggttggc ttgattatgg ctaagttttc gtccttgatt atagctagtc accagtcagc
     6421 tatgaacttt tcaagtctta tgtacgcctt tcctatgagt atctcatcgg ctatggctat
     6481 tgtcgtttcc tatgaagtgg gagccaagcg atttgatgat gcgaaaacct atattggtct
     6541 aggaagatgg actgccctca tttttgcggc cttcacctta accttccttt acatttttag
     6601 gggaaatgtg gccagtcttt atggtaacga cccaaaattt atcgatttga cagcgcgttt
     6661 tttaacttat agtcttttct tccagttagc agataccttt gcggcgccgc ttcagggaat
     6721 tttgcggggg tataaggata cagttattcc tttttacctt ggtttgcttg gttattgggg
     6781 cgtagcaatc cctgtggcta cgctatttga ttccctaaca gattttggag cttattctta
     6841 ctggatcggc ttgattatta gtttgattgt gagtggggcg ctctaccgtt ggcgtttaac
     6901 tgtgattatg aagagatttg aatctttagc aaaatccaaa cgctaaaaag tttgtgaaaa
     6961 aatattcttg ataagaaaat cccttgtttt cacggggttt tcttttttat tttgtgaaat
     7021 ttcttttaga aaaactttga cagtatttgc caaaaacggt aaaatagtaa ggtaagaaga
     7081 aagttagaaa ggcaagaaga tgtcaacttt agataaaaat cttttgctag aaatgttccg
     7141 taagatggaa gaaatccgtc gcatggactt aaaaattgca caattagtaa agaaagggaa
     7201 agtgccagga atgacgcact tttctgttgg tgaagaggca gctaacgtgg gggctatgtt
     7261 agctctcaat ccagatgatc tgattacctc aaaccaccgt ggacacgggc aagctattgc
     7321 taaagggatc gacctcaacg gaatgatggc tgaaatcctt ggtaaataca ctggaacctg
     7381 taaagggaaa ggtggatcta tgcatatcgc tgaccttgat gctgggaacc ttggtgccaa
     7441 tggtatcgta ggtggtggta tggggatcgc tgtcggtgca gccctcagtc agcaaatgca
     7501 aaataccggt aaaatcgttg tctgcttctt tggagatggt gcgaccaatg aaggtgtttt
     7561 ccacgaagca gtgaacatgg cttctatctg gaacctgcca gtcattttct attgcattaa
     7621 caacggttac ggtatctctg cggatatcaa gaaaatgacc aatatagaac atatccatca
     7681 acgtagcgcc gcttatggaa ttcctggaat gttcatcgaa gacggtaaca atgtcatcga
     7741 tgtctatgaa ggatttcaga aagctgtaga ccatgttcgc agtggcaatg gtccagtctt
     7801 gattgaaagt gtaacttatc gctggctcgg tcactcatca tctgaccctg gtaaatatcg
     7861 tacgcgtgaa gaagtggaat tgtggaaaca aaaagatcca atcgaaaacc tccgcaatta
     7921 ccttattgaa aataacattg caagtgccga agaattggaa gaaatccaag cgcaagtaaa
     7981 ggaagcagta gaagcttctg ttaaatttgc agaggaaagc ccattcccac cgcttgaatc
     8041 agcctttgaa gatatttacg cagactaagg agaaagagat aaaatggaaa caaaaacaat
     8101 gtccttccgt gacaccatta tccttgctat gtctgaggaa atgcgtcgcg atgaaaatgt
     8161 gttcttgatg ggagaagacg tcggtgtctt cggaggagac ttcggtactt ctgttggaat
     8221 gcttgaagaa tttggtccag aacgcgtccg tgactgtccg atttctgaag ctgccatctc
     8281 tggagcagca gcaggagcag ccatgacagg acttcgtcca atcgtcgata tgaccttcat
     8341 ggacttctct gttattgcca tggacaatat cgtcaaccaa gctgctaaaa cacgttacat
     8401 gtttggtggt aaaggtcagg ttccaatgac tgttcgttgt gcagctggta acggagttgg
     8461 ctctgccgcc cagcactcac aatctctaga gtcttggttt actcacattc caggacttaa
     8521 ggttgtggca cctggaacac ctgcggacat gaaaggcctg cttaagtctt ctatccgtga
     8581 taaaaaccca gttattatac ttgagtacaa gtcagaattt aaccaaaaag gggaagtgcc
     8641 agttgatcca gactacacaa ttccacttgg ggttggtgaa atcaaacgcc aaggaacgga
     8701 tgtaacagtt gttacttatg gaaaaatgct tcgccgtgtg gttcaagctg ctgaagaatt
     8761 agcagaagaa ggaatttcag ttgaaattgt tgacccacgt acccttgttc cgcttgataa
     8821 ggatatcatc ataaactcag tgaagaagac tggtaaggtt gttctggtca acgatgccca
     8881 caaaacaagt ggctatatca gtgaaatttc agctattatt tcagaatcag aagcatttga
     8941 ctatctagat gcaccaatcc gccgttgtgc aggagaagat gtgccgatgc cttatgcaca
     9001 aaacctagaa aatgcaatga ttccaacagt tgaaagtatc aaagatgcaa tccgaaaaac
     9061 ttataacaaa gaatagagtt acataagata agttatgtaa ataaaataaa gctgacgaga
     9121 aactttgtat cttttaggtg cagagctctt cgtcattaat atcttatatt cgagcacggg
     9181 ctaaaagctc ggaaaaaaga taaatctcct tggcttcatc gaagccatcg tcgatttcct
     9241 atttttcagt cgcttttgac gccctttgta tcataaatag aattggagag gtcatggctg
     9301 atgacaagct aagagcgact cctgcagcta gaaagttagc ggatgattta gggataaacc
     9361 tctacgacgt ttctggctca ggtgcaaacg gtcgtgtcca caaagaagac gtggaaactt
     9421 ataaagacac aaacgtggtt cgcatttcgc cacttgcaaa acgaattgcc ctcgaacata
     9481 acattgcttg gcaggaaatc caaggaaccg gtcatcgtgg taaaatcatg aagaaggatg
     9541 ttttggccct gcttcctgaa aatatcgaaa acgatagcat caaatctcct gctcagattg
     9601 aaaaagtgga agaagtccct gataacgtaa caccatatgg tgaaatcgag cgtattccaa
     9661 tgacaccaat gcgtaaggtt attgcccaac gcatggttga atcttacttg actgcgccaa
     9721 ccttcaccct caactatgaa gttgatatga ctgaaatgtt ggctcttcgt aagaaggttc
     9781 ttgagccaat catggaagca actgggaaga agactactgt aacagacctt ctttcgcttg
     9841 cagttgttaa gactcttatg aaacacccat acatcaacgc ttcattgaca gaagatggca
     9901 agactattat cactcacaac tatgtcaatc ttgccatggc agttgggatg gataatggat
     9961 tgatgacacc tgttgtttac aatgctgaga agatgagtct ttcagaacta gttgtagcct
    10021 ttaaggatgt tattggccgt accttggatg gtaaattggc tccaagtgag ttacaaaatt
    10081 caacattcac aatcagtaat ttgggaatgt ttggtgttca gtcctttggc ccgattatta
    10141 accaacccaa ctcagctatc cttggtgtca gttcgacaat cgagaagcca gttgtcgtca
    10201 atggtgaaat tgtgattcgc ccaatcatga gtttaggatt aaccattgac caccgtgtcg
    10261 tagatggtat ggctggtgct aagtttatga aggacttgaa agagttgatt gaaaccccaa
    10321 tctcaatgtt gatttaagag caagagtatt catttttaag atatagataa aggaaggaag
    10381 acatggcctt agaaataatt atgccaaaag ccggcgtgga tatgacagaa ggacaaatcg
    10441 tccaatggaa taaaaaagtc ggagaatttg taaaagaagg agaaatcctt ttggaaatca
    10501 tgactgataa agtcagcatg gaattggaag ccgaagaaga tgggtacttg attgccattc
    10561 tcaaaggaga tggtgaaact gtccctgtaa cggaaattat cggttacctt ggtgaagaaa
    10621 gggaaaacat cccaacagct ggagcagcat cgccagaagc tagccctgta cctgtagcaa
    10681 gtacctcaaa cgatgatggt aagagcgatg atgcttttga tatcgttgtg attggtggag
    10741 gtcctgctgg ttatgttgca gccattaaag ctgcccaact cggcggtaag gttgcccttg
    10801 ttgagaaatc tgaacttggt ggaacctgct taaaccgtgg atgtattcca accaagacct
    10861 accttcataa cgctgaaatt attgaaaata tcggtcatgc tgcaaatcgt ggtatcgtga
    10921 ttgaaaatcc taacttcact gttgatatgg aaaaactttt agaaactaaa tctaaagttg
    10981 ttaatactct tgttggtggt gttgcaggac ttcttcgtag ctacggagtt actgttcata
    11041 aaggaattgg tacaatcact aaagacaaga acgtcttggt aaatggttct gaattgcttg
    11101 aaaccaagaa aatcattctt gctggtggtt caaaagtcag caagatcaac gtccctggta
    11161 tgcaatctcc acttgtcatg actagtgatg acattcttga aatgaacgaa gtgccagaaa
    11221 gccttgttat catcggtggt ggagttgtcg gtatcgaact cggtcaggcc ttcatgacat
    11281 ttggttcaaa agtgactgtt atcgaaatga tggaccgtat agttccagct atggatgcgg
    11341 aagtttctaa gaaccttcgc ttgatccttg agcgtaaagg aatgaccatc ttgactggta
    11401 ctaaactgca agaaatcatt gaggaaaatg gtcaacttcg tatcaaggtt gaaggaaaag
    11461 acgatatcat cgcaagcaaa gctcttcttt caattggtcg tatgccagac cttgaaggta
    11521 ttggagaggt tgagtttgaa ttggatcgtg gttgtatcaa ggtcaacgaa tacatggaaa
    11581 cttcagttcc aggcatttat gcaccaggtg acatcaacgg tactaagatg ttggctcacg
    11641 cagctttccg catgggtgaa gtttccgctg aaaatgccct taaaggaaat catgcagttg
    11701 ccaaattgaa tttgactcct gcagccatct acactctccc tgaagtagca gcagtaggtt
    11761 tgacagaaga acaagcccgt gagaaatacg atgttgccat cggtaagttt aactttgctg
    11821 ctaacggtcg tgctattgca tctgacgcag ctcaaggttt cgtaaaagtt atcgctgata
    11881 agaaatacgg agaaatcatt ggtgtacaca ttattggtcc tgcagccgca gaattaataa
    11941 acgaagcatc aagcatcatc gaaatggaaa tcactgttga ggaaatgctg aagaccatcc
    12001 acggacaccc aacttactct gaagtgatgt atgaagcgtt tgcagatgtt ctaggaatgg
    12061 ccatccattc acctaagaaa aaataaaacg aagatagatt agactggaag gttatttcca
    12121 gtctctatca tataaagtaa agggatatca tgaaatacat tatcaatcat tcaaatgaca
    12181 ctgcttttaa tattgccttg gaagaatacg cctttaaaca ccttttggat gaggatcaaa
    12241 tcttcctact ttggattaac aagccatcta tcattgttgg tcgtcaccag aacactatcg
    12301 aagaaatcaa ccgtgattat gttcgcgaaa atggtattga ggtagttcgc cgtattagtg
    12361 gtggtggagc tgtttaccac gatttaaata acctcaacta cacgatcatc tccaaagaag
    12421 atgaaaataa ggcatttgac ttcaagagct tctcaactcc ggttatcaat accctggctc
    12481 aactcggggt taaagctgag ttcacaggtc gtaatgacct tgagattgat ggtaagaagt
    12541 tctgtggcaa tgcccaagcc tatatcaacg gccgtatcat gcaccacggt tgcttgctct
    12601 ttgacgttga tttgtcagtc ctcgcaaatg cccttaaggt ttcaaaagat aaatttgaat
    12661 caaaaggtgt gaaatccgtc cgtgcccgtg taaccaatat tatcaatgaa ttaccaaaaa
    12721 aaatcacagt cgaaaaattc cgtgatttac tcttggaata catgaaaaaa gagtacccag
    12781 agatgactga atacgtcttt tcagaagaag aattggccga aatcaatcac atcaaggata
    12841 ctaagtttgg aacttgggac tggaactatg gtaaatcacc tgaatttaac gtccgtcgtg
    12901 gaaccaaatt cactagtggt aaggttgaag tctttgctaa cgttactgaa tcaaaaatcc
    12961 aagacatcaa gatttatggt gacttctttg gtattgaaga cgttgctgca gtagaagatg
    13021 tccttcgtgg ggtgaaatac gaacgcgaag atgttcttaa ggcgctaaaa accattgata
    13081 tcacacgcta cttcgctggt attagccgtg aagaaatcgc tgaagcggta gttggataaa
    13141 tcaaaaaaag aagttggcca acttcttttt ttgatattta tttacataat ttaaaatacg
    13201 tgaaatcata aactatctag agcattcttt tgttcatcat taacaatatg ggtatagagg
    13261 tcagtgactt gtgtgctggc atgtcctagt tggtgactga ctaaaacttg tgatttagtc
    13321 gcatcataga gcctagttgc tagcgtatgg cgcagtttat ggggtgttac acgtacttta
    13381 aaatcctctg agtatttagc aaccattttc tcaacgctag aagcatcgat acgattagga
    13441 acacctctgt agagagttaa aaaaagggct gtatctgttt tttccgtttt atagcgttga
    13501 ttccgaatgg ccagataatt ctctaaataa ggtttagcaa aagcagcgac attgactgag
    13561 tcacgtttgc caccttttcg agtaacatca ataaccatca tttttagatt gagatctctt
    13621 agatctagat taacagcttc agataagcga acaccagatg ccaagagaag ggcaataatg
    13681 gctaaatctc gttctttatt tttgttgaat gatgagagag ctcgatttga aagctgttgt
    13741 gggtgctctt gatcgatata agttagaaaa ccttctgttt catcacctag aaagagtttt
    13801 tgcttgatat tttcagctct ggcagcaagg gtttctttct ttttcttggt tgaaactttt
    13861 ttcattacat tacgatagaa ataaggttcc ccctgatcgt tttcaacctc ctcggttaga
    13921 tacttgtaaa gactagaaag tgctgataag gttcgattga tagttgtctg tgaaacacct
    13981 tgttttgttg tattagcatt cagcaaggga cgttcacgta gataaaggat aaaggattcc
    14041 atgtctttct tagacatatt ttccaaaact gataaaggaa tatcggatat tttatcagcg
    14101 tttgaaatac cagactccaa aacccagctg aaaaatcggt catattcctt aaggtattcg
    14161 tacagggttg taaaactgta gggcacagcc agcttagatt ggtagtattc cagaacatac
    14221 cagggcatga gttgttttag tttgtcgatt cgttccagta aaatctcacg tttcatgtat
    14281 tttctccata agtaagtata ctagtagtat agcatagact tgtatatttt tcaagaaaat
    14341 tatagttttt cagaaagatg ttataggagt ttttcaaagt gataaaaaga cttagaccta
    14401 caaacaaaac agaataagga aaataataaa aatctcaccc actaaacttc tgttaatact
    14461 acataactga agagctatat aaggagctat gagatacaaa acacattgta taatagattg
    14521 aaactagaat agtacatctg gacttctaaa acattgctag aaattgattt gattgttctg
    14581 attgttttat cctatttcta tttcatttca ctatataatt gctattgttt tctttttcat
    14641 gattttaatc ttactgtaca gatttgatac agtaaactcc tttctagctt tatactttat
    14701 catttctaac ttaattatag tcttattttt aataaagttc aattatttat atgtaaaatt
    14761 cctcatcagt aaaaaataac cgatctcatt tctgagaatc ggttttctaa ataaatcaag
    14821 ctgagtattt acataacata aattatgtaa atactcatac tacaacaaca aatctttgac
    14881 ttttccaatt tcactttttg gaataaccag gtgaatcata tcacccagat acattctggt
    14941 tgagccgtta actgtttggc tcttgccatt atggacttga gttgtgatga ggacgttgtg
    15001 tggtaagttg agttcatgaa cttgtttccc agcaatttta tcagaaactg gtatttcgat
    15061 aagtgtaact tctccttcgc tagatacttc ttctggaagc attttttcca gcatggcttc
    15121 atagactggc gtacctttga gcaaatccat gataatataa gaaacaagag tgacaagacc
    15181 aagtggcatg aggttgcgaa tatctcctac catctcagtt acgaggatca tagcggttaa
    15241 gggagctttt gatatggctc caaaatagcc actcattcct agaatgacaa atatagggaa
    15301 ttgctcttga ctgacaagtc caagattgac acagataaca ccaactaagg aaccaagcaa
    15361 agaaccaaga gctaaaatgg ggaggaaaat tcctcctggc agtccacttc catagctaat
    15421 catactccaa ataaagcgga tcaaaaagta agctaataaa acttggaaac taaaattttg
    15481 ttcagttaaa gaaaggacaa gctgatttcc gccaccaatg atttgaggta agaagattcc
    15541 gactggtatg ataatgataa aagccaagat gggataataa gccctatcca aatggatttt
    15601 ttgaccaatc aagtcataaa ctcttccaac gtttaataca gctttctcat agagaaaacc
    15661 tgaaaatcca aggaaaattc ccatgacgag atatatccaa tactggtcta gggtcatggg
    15721 aggaatgtta tctggcatat ccaatactgg tgtcaaaccg aacatgagta gagacacaaa
    15781 gtttgctacg atgctggctg ctagagttga gacccagaaa aagcgcgaaa aatggtgata
    15841 gacttcttct acaacaaaga gaagtgctgc aataggagca ttaaaggctg cggctaaacc
    15901 tgctgcagct ccactggcaa tcaaggaacg ttcctctact ggactggatt tgagccactt
    15961 ggcaattcct ttaccaccaa ctgctccaag ttgaatgctg ggtccctctc gacccagcat
    16021 gagtccactg gcaatagcaa gaatacctag cacatatttt ttccaaagaa tgccccacca
    16081 gttgagggac atgaggcctt tcagttcggc ttcgacttga ggaattcctg agcctttaat
    16141 atctttttct gaccgtgtta gtttggcact gagccaacag atgagtatat aaaacaaaac
    16201 cagtacaaaa agattgcgca ctaagtaccc ttgatcttga taaactcctt gtatcaggtg
    16261 gaagcccttt tcaattaaga aacgaaagga tccgacgata attccaacga tgaggccgac
    16321 aatgattcct cgaccaactt gggatagtat agtgctggat gcaaaggcga attctttctt
    16381 agaacggact atttccgact gttcctccat ggtatttcct ttcaattaac tttctttttt
    16441 acctaaaacc agtgatttaa cgggttcaaa gctggttcgg tgaattgggg taactcctag
    16501 ttttgtgagg ccttccagat gtttagctgt gccatatcct gcattagtag cgaaatcata
    16561 gccagggaac tgctgatcgt attccttcat aaattcatca cgtgttacct tggctactat
    16621 agatgctgct gcgatagaga gggagttggc atctcctttg ataatggagg tttgtgaaat
    16681 gggcaagtcc agtttcatgg catcaatcaa aaggtgctct ggttgagggc tgagctggga
    16741 gattgcttct tgcatggcta gtttggttgc ttcatagata ttgacttggt cgatgacctg
    16801 attatctatg ataccaattc caatcgacaa ggcttggtct tgaacgactt ggaaaatctc
    16861 cagatgtttc tttttaggaa ttttcttgct gtcgttgaga cctttaatct tacaattttt
    16921 aggtaaaata acggccgcag cgactacagg accagcaaga ggaccacgac caacctcatc
    16981 aatacctgca attaaggtca atccttgctt ataaagttct ttttcataag aaagcatgga
    17041 ttccaagcgc aaattttcat ctaattcagc ttgaatggct cttttatgct tgctgatttc
    17101 cttttgaact cctgagcgat tatccttttc aagatctaaa aaaatagggc tttctaactc
    17161 cttgactgtc acaaggagtt ctttgatttc tttaatcgtt gccatcgagg ccttccaatg
    17221 tatctaaggt atagttaccg agtttgccat cacggacttc cttcacgaag agactgtaaa
    17281 aacggtcata gtcatcacgg aaaccgaggg cgcgggtcat atccataata atcacaggcg
    17341 cttcttcttc aattttcatt tgtttgaagc gttcagccag cttttctgga taatgttctt
    17401 tgaaataatt gataccaaaa atggtaacct catccatagg aagcaactga tccttgatag
    17461 ctccagtcaa tgccaactta agtgcaacag tttcatcctc aaacttaggc cagagaatcc
    17521 ccggtgtatc caagatttcc agatctttat tggttttaag ccattgttga ccttttgtga
    17581 cccctggctt gtttccaaca acagcaatct ttttaccagc caaacggttc atcagagttg
    17641 atttaccagc gtttggaatc ccaataatca tggtacgcaa ggtttcaatc tgaatcccac
    17701 gttctttctg gcgagcaatc ttatcagcca tgagcttctt ggccgcatct gttacaactt
    17761 ttacagtcac ttgctctttg gagttgatag ctagcgtctg gattccttgt gattcaaaat
    17821 actgacgcca ttccttggtc attgctggat cagccaagtc ggccttgttt aaaatcaaga
    17881 gttttggttt atcaccaaca atcttggtta acataggatt ttgactagat agaggtaagc
    17941 gtgcatcaac taaaatcgtc acaaaatcaa caaattttaa attctcctgc acctgtcgac
    18001 gagctttaga catgtgacca ggaaaccatt gaatagtagc cattgagttt tttcctttca
    18061 tagcaaggat ttagatcccc tattttattt tactattgtt tgaacataga gagttttcaa
    18121 atgaatgatg tccaaacagt tcttgtttta tgacatagaa atctacttta tattatatca
    18181 tgccttcttt attttgtccg atgatagcct tttaccctat atagaaaaaa gccatcaaat
    18241 gatgactttt cagagggagc aaaaaactgt tcccgtcata ttatgaacca aaagaactaa
    18301 actaccaaca gctaataggc ctaaagctgt aagtgcagaa gttgatgaac ctgttgcagg
    18361 aagagtttcc tgctgataaa taagagcata acttacttca ttatcagtag gaattcctgc
    18421 ttgaatcttg gtttgttctt catcaccttt ttaaacttta tttcctaata gtaaacacta
    18481 ttttttattc tcaaaaattg aacttctaaa atcatttgtt tggtcaagat aggctttaaa
    18541 gattgctctc ttcaacttat gaacggcact gtcgatttct ggatcataat tactccaacg
    18601 tggaccttca gcatccttga gaacagcttg gtccatgagg gcttgcaatt catccacatt
    18661 attgatagtc tttgtgccat agcttggcca tggttttgtc ggatctttaa aggtcacctg
    18721 cttcaagttt ccaaactgat ccactcgttc ttggtacata gctgtcttaa attctgccca
    18781 agttttatac ttaccgtcaa ataccttttt caaaacaagc tcatcggtca ccaagccccg
    18841 ttctttacca taaagattga tagtttgccc ttgttgttta gcatcttctt cgtattggtt
    18901 tgagatataa ggtaccattc catccttaaa gcctttggca gccaaaagtt cgtacgcaat
    18961 cctacgtccc ataaggtccc ctggtgtgcc tttctcactg ctgagagctg aatagattgg
    19021 ggcaaagagt ttgatggtat agtagccatt tcgttcatag tcgccagact ggtactcacg
    19081 agctgataag atgttgtggt caatcaaact ttcaaaacta ttcaggtttc gggcctctgc
    19141 ttctgtcaat tctttgacta cgttagtggc ataaacctca tttccatctg ctggatcttt
    19201 cacatacttg ttctcaattt ttctgagagc cgccattttc tggtaaacac ttagtttatt
    19261 aacgattgac tgcccttcga gatattccat catgtagata aggtcaaaca tgttatggac
    19321 atagttctga agatctgctg cgttttggaa tctctctgtc ggatccaaga cttgaagacg
    19381 ggatccctct gtactatctg attttgagtg tttcaagata gaattaatgg taatggttgc
    19441 gtcacttggt tggtcagggg cttgcaataa gccttttgcg aagaactctg gtcccaagcc
    19501 atttcttcga ccatagccac caaggtaaat atcctgatcc gaatcatggg tcatttcatg
    19561 ggtataagta atggctccat ccttgtccag catgcggtaa gacatatagt agacgccgtc
    19621 ccctgtagcg taggctccat gctggttgtg tactacctta ttgccaactg gtccaaagaa
    19681 gttcttcata gctggattgg agctatcaaa cttagcctcc gctgtagctt ttcctgatgt
    19741 tgtgtcatcc ccaaacttat aggcatcata aaggagaatc gtacgataga gtttttcgcg
    19801 tgactgttca tctaaaatac gataccaata atcgtagtga tctcgctgac gtttggctgt
    19861 ttcacgcgca ttttcttcaa caaaatcatt gagagccttg cccgctttat ggtcactact
    19921 gcggtagcga tcataagctc caaatcctag actagacatg gtcgagatga caaatacgga
    19981 tctctctggc aaggtcagga gaggcaagac catattgcgg tatttccatg tggcactcgt
    20041 gatacgatca taaacaccga tagaatactt ggtgccagct aacccttgct tcgttttcac
    20101 ctcttcgata gtggattttt cttcgacaat gtaagcctta gtctctgatt taaaccagtc
    20161 attattgctt gtatttggta aaaagacttt tcggtaatgt tccagcgtgc taaacaaatc
    20221 tgtcgttcca tgttgactgg caagactgat accataagta tcgacattat tcttagctag
    20281 aagattgtta aagccagatt tacctaactc aatcagagta tctagtgggg aagtatttcc
    20341 tttaccaaag aagtctggat gatacataac taggtctttg acattcactt gaccatagtt
    20401 aaagttatac caacgttcta aataagttaa accgagtagc aaggcttcct tattattctt
    20461 gattttatct acaagatagc ctctggtgac tgagttatcg ctagctagac cggcatctgc
    20521 tgacaaaagt tttttcaagc tgtctcccag attttgtttt gttttggaga actggtcttc
    20581 taaatagagc tcggttaact taacttctgg agaaatacca agtgtctttc tgatagcatc
    20641 tgactggtaa tcaagcttct gcaactcagg caagacttcc ttaacaatag agtctcgatc
    20701 atataagaat tggttaggag tgtagagaag tcccgtatta cctagattat attctgctag
    20761 attggcaaaa tcagtctggt acttgagatc aaatttctca gatgaatggt cattatagtg
    20821 aagtaagagt ttgtttgcag tctgtttgtt ggaaacaata tctgtgatta cttggtcatc
    20881 cttcatcata actgcagata agagttcttt ttggtataag agactgttct ccttaaccag
    20941 gtttccgtat ttgacgatgg ttgacttatt ataaaaaggt aacaattttt caatgttctt
    21001 ataaaccaaa gcacggttag cttgataatg ggctatctta gaaaaatcac tgtctttctt
    21061 gccacttgtt gagaggggtt ccaccgttgg tagagtgaga ggatttattt ctgctttttt
    21121 gcttacaatt tgagaagcat ctagcattgt tcctctttct tcaaaggatt ccttgctgac
    21181 gacctcatcc ttctctaaag tgacattgaa aactctatta gccttactac taaatgtatt
    21241 agctaccttc attcctgtat agtggtatcc agtgatggca tttccgtttg ttacattgac
    21301 atcgctaaga acattggtca attcaccagc gtgtttttcc tcaccagaag ttcgatccca
    21361 caaatatcct gccacaccag cgactttacc aaagtgcttg acattattaa tatcaccttc
    21421 cgcataactg ttctgtatat gcgcatcttg gtctactaga cctgcaagac caccgacagt
    21481 ctgatctgac ctattggtgt ttgacgaaat ggttactgtc gctttggatt tagcaataga
    21541 cgcatttttt cctgttaaat gaccgaccag accgccaata ttgtaggcat cagtcgtttc
    21601 ataggtattg acaattcttc ccttgaaact gctctctgcg atgcttgatt ggtctgcctt
    21661 agccaacaaa ccaccgacac cacgttctcc agccagaaca ccatcaacat gaacttgttt
    21721 aatctttgtg ccattcgtag cttcatttgc tagtgaacca atatcatttt tccctgaaat
    21781 agcaacattt tttagactca gtttttctac tgtagcacca ctcaagtttt caaacagagg
    21841 ttttttcaaa ttatagatag cataattctt gccatctttt tcaccgatta aacgaccagt
    21901 aaaggtgtcc ttgatatagg atctttcatc aggaccaagc tccacttcgt tagcattcag
    21961 gctggccgct aaatgatagg ttccagaggg attttggttt atagctttga ccaggttgct
    22021 aaaggaagta aagtttgtat tttcctcttt agccttctta tcgaggtaga aggtgaaatt
    22081 gtcgacatat ttattttcta gttcttgctg gagtttctca gctttggctg tgattttata
    22141 aactgactgc ccatttcttt tctcttcagt tattgaagct actggtatat agacatcttt
    22201 aaatgctgaa gattttacct tgacaaagta agtatccgta ttctctggaa ttccatccaa
    22261 tgaaacatgt tgtctgtagg ttccattcgt ctgactatac aactcaatat cagaaacatt
    22321 tcttaattcg agttttttct ctggttctgt ttgtccattc tctgatgttg tattacctga
    22381 attttctggt tttgttgcag ttccgttttt ttctggttga tttgattctt caactggtgg
    22441 ttttgaatca ctaggtttat tggatacttc tccagtattt tcgttagcta ttttcccaga
    22501 gtttgtttgt gtttcttctg caggttgaac tggtttttct gtttcttgat ttgaggtacc
    22561 ttctactgtg ccttcatttg gatttactgg aacttcttct acagtttttt ctgaattttc
    22621 atttttagag tcattatgtt ctggtttatt tgattctcca actgaggttg tcgaatcact
    22681 aggattactg gacacttccc cagtattttc gctagatgta tctggtgata ctttctctga
    22741 attcgttgtt gattcttctg caggttgaac tggattttct gcttcttgaa ttgaggttcc
    22801 ttctgtagta ccttcatttg gatttactgg tgtttcttct gttggtttta ctggaacttc
    22861 ttcagttttt tctggacctt gttctttggt cttctcaacc ggagtttcag gttttacttg
    22921 ctcaatatta cccttatatt ctggcaatgg ggctacctgc tctggttcac ctttatcact
    22981 taccacagta tctggcgact ctggttgaac ctcagtctca cctttgtcgg tcacaactgc
    23041 ttcgggtaat gtcggttgaa cttctggttc gcctttatca cttactacag cttcgggcaa
    23101 ctcaggctga attgcgggtt caacaataga tccagactgt acgtccttat gttctacacc
    23161 agtctcaggt tgttccttta taacttgagt ttttttagta cctttttcga ctattcttgg
    23221 actaggcgca gtcgttgaag ttgaaacaat ttctcgcgaa acttcttcct tgtttacaga
    23281 gaatattctg acgatttcaa ctttcttacc taatttacct tcttgtttta ctcttacagt
    23341 tccttcagct aaatcaggat tttcttgaat ttcttcttga aaatctattt ttgtctctat
    23401 agtttcctca cgatataaga gttcaggttt gttcaattga cctgataaaa cttcatcctg
    23461 tggatttaat gtatttaccc cagtcttttc ttttggagaa atcttctcct ctttcttcgt
    23521 ttctagattc ttatgttcgg ctaattgttc ttgagaatct gaagattgtt tctcttcttt
    23581 tcttggattg attaattcag tagagaaagg tttttcaact acttgaactt ctgtcggctt
    23641 agttgaagaa acaggtgttt gttcctgaat agcttgtact gttgatggat ggtctacaaa
    23701 atttggtgta acattataat ccaccttttg ttgttttgta ggagtggctg ctgatttttc
    23761 ttgattactt acttcaaaat cagaagtcgt ttttccctct ttgatatatc caatataagt
    23821 gtaacctgaa atctctttag gaagaggtaa tttttctcca gaggtcaatt catagtccgt
    23881 attgtaattt agcaaaagat gattttctaa agcatggact gaaactaaga caccatttcc
    23941 cattcccgca accaatacta aatgtaatac cgttttattc ttaacctttt tcttggaaac
    24001 agcaaaaatt aaaattccca gagcagctaa gctagcacca gcaactaggg cttgcctctc
    24061 attcttgctt ccagtatttg gtaattccgc cagttgattt tgagaattta acttataaac
    24121 aagataataa gtttcatcat cattctccac gtatgtcgga atatcataga caagctgctt
    24181 cttttcttct gatgatagct ctgaatctgc cacatattta tagtgaactc ccgcagtttc
    24241 ttgagcatcc acagatgaac tagctaatac agacataaaa aataaacttg aaatcgttgc
    24301 agatacaagt cctactgata attttctaaa tgaaaaacgc tcttgttttt caccaaaata
    24361 cttttccatt attcctcctt gaaataaaat ttatatatgt tacaaagacc tttattatat
    24421 tagtgtatta tctattatct atagaaaagg cagtatacct taattatact cttaatttac
    24481 aaaaaagtct taaaattgag atgcgctttc atactttgtt ttatattatt tgggggtaca
    24541 ataacaccta ccatgaaatt tacacggtag gtgttactca tatcactaat cgttctaaaa
    24601 atggtttgag gcagttgagg agaattcctt ctatccagct tccttgtgct gatgagcgat
    24661 ggtcttcctg caggcttttt tttagaaaat ctcggacttg ttctggtgcg atttcaaatt
    24721 caaaggcttt cattttatag aaaaagtcga tgagatgatc tgacaggtat tcagttgaaa
    24781 agggtacttc accacttttt cgatattcta ataagagtct agaaaatcga gctttttctt
    24841 caggaagctc acgaaaatag gaattgagga tccaagtctg cttctgtttt ctttcaattg
    24901 gatcctgact ggcaattcgt tggtcttttt ccagctcttt ttggtattgt ttggccttga
    24961 tagctcgttc tgctctattt ttaccaaaaa gaattttttc ccacttgcgt tcttcttgag
    25021 tcagggtctc tgtaaagcca aagtaatctt gataagcacg ctctgcgggt cccatggcta
    25081 gaaccagatt gtctgcatat tgcttggcga ttttatccct cttcttgcgt tctttctctg
    25141 cctggatacg gagttcttgt tcgtagtcaa ttttctcctt gcctagcttg acaaggtaga
    25201 gttggtcatc cgatttccca agtaaaaagg gtttgataca cttttcaagg acttcttcca
    25261 tccgagcctt tttctttggt tccgccttgg tccaacttcc tccctgaaag acttctagga
    25321 aaagctggta gtctctctca ggcgcaaatt gattgccacg attgggtttg aaaacacctt
    25381 tttcccagag ccattttaga agtcgctcgt caaagtcact tttattgacc ttgatttttt
    25441 cctttttctg agcttttctg gttagatttt caacctttct gagcagtttt tcttcctctt
    25501 ccaattgctg gtcaaggggc aatcgatgaa aatgacgaac acagtcgcta ccaattggaa
    25561 agaggcgttg gcctgtgaca ccgttaaaga gttcataagc gtatttgatg gcatttcgac
    25621 agacacaatt gctacggcca ataccgttaa aaatcaagga aacttcattc cattccttgg
    25681 tagcttgttc ccaagtatcc gctttcgaag cctgtaaaac tgcatcgtgc agggattttc
    25741 taactggaag tgtcatgagg tctcctttct aatactcaat aaaaatcaaa gagcaaacta
    25801 gaaagctagc cgcagtcagc tcaaaacact gttttgaggt tgtagataga actgacgaag
    25861 tcagtaacca tatatacagc aaggcgaagc tgacgtggtt tgaagagatt ttcgaagagt
    25921 ataagttata cttttacaac ttgaacctcg tctttaccga gtaaaatcaa gtatttttca
    25981 atattttcaa tcgaataggc tcgtgataaa gcctcttcgt atagagctaa ctgaccacga
    26041 tagcggtcta cgagttgact tggttcatca tagcggtctg tcttgtagtc gaacagaaca
    26101 attttgtttt cgtaaagcag atagccatca aggataccac ggacaacaaa gtcttcctga
    26161 ctcttttggt ctcgtttgag catggagaaa ggttgctcgc gatagagatg gtcggtatta
    26221 gcaagaattt cctgaccgag tgctgtgtca aagaaagcaa gaattttatc aagattgatc
    26281 ttgtctctga cagcttggct agtttgaact tgtttgagtg tttctgttaa gctagcaagg
    26341 gttagttgct ggctgaggtc aattatctgc atgagttcgt gagtagcact accaatctca
    26401 gctccagtta ccttttcttt ggttgaaaaa tctggcaaat cgaagctgat tttcttgcct
    26461 actgactgac cttgaccagc aatctcgaca ccttccatat ccataactgg ttcgtagaat
    26521 ttcttgattt gacttggggt ttgaacacta ggaagttcaa tagctgcgcg gtgaagagta
    26581 ttataaactt ccacctcctt cagcatttcc agagcttctt tgatggtatc tgactgacga
    26641 ttgtctgctt gggagctatc ttggagagga ctcttggttt ccaactctcc gatagcttct
    26701 ctggtcaact gatcttcgtc aataaaacga taactaaagt tgagcttgtc cttagtaaac
    26761 actttactga tagcccaaag ccaatcttgg aaattccgtg cttgcagtct agtattgcta
    26821 tttagtttcc catttttggc tgctgggtat tccttggatt ccagcttttc acgagaaccc
    26881 ttgccgacaa gatagagctt tttctcagcc cgcgtcatag caacatacag caaacgcatc
    26941 tgctcagaat agcttgctag ctgtaattcc tcttcgttct gcctataggt cagactagga
    27001 atggagagtt tgatggtttt aggatagtgg tcttctactg cccctgtctc catcttggca
    27061 atatatttga caccaagacc attctgacga ctgagaatga cttctgacat agagtcttgc
    27121 ttgttgaaat cttgatccat attgaggata aagacgtaag gaaactccag ccctttactc
    27181 ttgtggatgg tcatgagctc tactgcatct tttggcggtg cgacggccac gcttgccaaa
    27241 tcgtgctggg cttctaagac ttggtcaatc atacgaataa aacgcgacaa acctttgaaa
    27301 ttgctctttt caaattgatc agcacgcagt gctagggcat agagattggc ctgcctagca
    27361 ggaccattcg gcaaagcccc aacatagtca taataaaaac ggtcgttgta aatcttccaa
    27421 atcaagtcat agagagagtg ggttttggca tacaagcgcc aagaagctag gatatccatg
    27481 aattgcttta gtttttcaac tagagctgtg tgaatcaagc ctttttgact acttgccatt
    27541 ttttgtgcat tgaccagttt ctcatagaga ttttcgtgga ctttatcctc tgctttctga
    27601 agggacaaac gtgctagctc atcctcatca aaaccaaaca ttggagactt cataagggca
    27661 accaaggcgt agtcttgcag gggattgtga atgacacgaa gagtgtctag catgacttgc
    27721 acttctaggg attggagata attgttttgc tctccgtcag ttttgacagg aatcccgtac
    27781 tcagacaggg cgaggagaat ctggtcatta cgactgcggc tggaggtcag aagggcaatt
    27841 tccttaaagg caacaccttt ttcttgatga agtttcagaa tctccttgat aactaagcgc
    27901 atttcgcctg ttagtttcgt ttctgtttga ctctcttctt cctcacctgt atcgtccttg
    27961 tcgtagagga gaaattctgc cttgttgtct ggattgggag tcagtttggt attggcaaaa
    28021 acaagctggt gcttgttatc atagttgatt tcaccgacct cttggtccat gagacgttca
    28081 aagacatcat tggttgctga cagcacttct gaactactac ggaaattttc cttgaggaga
    28141 atgagcttgc cttcttgggg attttgcgca tagcgttgga atttctcatt gaaaatctgc
    28201 gggtctgcct gacggaaacg atagatggat tgcttgatat ctcccaccat aaagcgattg
    28261 tggccattag acaacaattc cagcatccgt tcttgaatat ggttggtatc ctgatactca
    28321 tcgaccatga cttcatggaa gcgctcctga taagactcac gaacttgtgg gaaattctct
    28381 aaaatctcaa tggtgtaatg gctgatatca gcgaattcaa aggcattttc ctggcgtttg
    28441 cgctgacgat aagcctccac aaaatgactc ataaaggttt ggaaggtttt agctagtttc
    28501 catgtgtctt gatgataacg ttcttgatag tcgagaatgg ttatctggtc tgataattgt
    28561 cctagtttag caaactgggt ctttctctct tcgttgtagg catcagccag gggcttcaaa
    28621 tcagccttac gactggcatt agtcagagct cgaccgtttt tctccttaga gatggcgaca
    28681 acacgcgcaa gcactgcctg ataagcctga ctatcggact cctgatttag ggagcaaatt
    28741 tcatccagaa ttaactgaac attttctaaa taggcagcct ttgcaaactc cttggcatcg
    28801 ttatccagat ggtaacggaa aaagctttcc aaatcccaaa gggcttgttt gatttgctca
    28861 gtcagttttt ctttttcact ggtaaaatca gctttctcaa atcctttgag gaaagattca
    28921 ctcagccact tttgaggatt actggtggat tggaggaagt catagatttt atagacctgc
    28981 tggcgcagac cccgttcgtc cttgccacgc ccagcaaagt ttttcagcaa atgactaaag
    29041 gtctctttct gtttaccttg gtaatgcgct tcaaagacct catgaaagac ttcgttttcg
    29101 agaagaagtt gctcgctttg gttttgtaaa atacggaaat taggtgcaat atcaagcaga
    29161 taaccatgtt tgccaaggaa tttttgtgtg aaagagtcca tggttccgat ggcagcgttt
    29221 ggtaggtctg ccaactggcg tcccaagtgt tgtttgaggt cgacatcatc tgtttcttgg
    29281 attttcttgc tgattttttt ctctaaacgt tctttaagtt cagttgcagc cttgacggta
    29341 aaggttgaga taaagagttg agaaatttcg acaccacgcg ccaattggtc cagaatgcgc
    29401 tctgccatga caaaggtctt tccagaacca gccgatgctg agaccaggat attctgacca
    29461 gaagtgtaga tagcttcgat ttgctcggca gttttctttt gttccttgct cgaatttgct
    29521 tctgcttctt gcagtttttg aatctcctcc tcacttaaaa agggaataag cttcatcgat
    29581 tcaactcctc tcttattttt tcaagccaag cttgcttgag tttttctccg accagacgct
    29641 tgccatcagc taggtccaac ttttctagga aacgggcttg gcccagatgg taattggctt
    29701 caaagcctgt aatagcctga tgttgctgga cgtatggggc aatgcttctg ccattttcag
    29761 tataaggatt gatggcgaac cggcctgcta aaatcttctc agcagctttc ttgtaaagat
    29821 aggcattgta gtccagtagg agctgaaatt cctcatctgt cagttgattc gccttgtttt
    29881 tgttataaaa ttcgcctaaa taactgcttt ctttttccaa gaagagccct tggtatttca
    29941 tagatttgct ggcttctacc actgctcctg ccagactttt taccgccatc agagattgga
    30001 caggttcagc catttccaag tacatggcgc cgaaaaagtt ctgctcccct tctcttttta
    30061 gggcagcaag ataggttggt aactgagaat tgagcccatt aaagaaatga ggaaactgga
    30121 actgagtcag actggatttg tagtctacta ctcctatcgc tccattagct ttcaaacggt
    30181 caatccggtc caccttgcct cgtacaaaga cactgcgtcc attgtctaat tgaataaagg
    30241 cttggtcttt tccaccaaaa tttgcttctt ctttgattgt ttcgatggct ggattgtgtc
    30301 ggagaatatg tccagttgtc cgtgcaacat caagcaaaac ttccttggta aactgggctt
    30361 ccaaactttc ttgataaata gcttcaaatt cgcgttcttg actggtttct tgaatagctt
    30421 gttctagacg ttggtcaaag gaatcttcat taggcaactg caaggcgcgt tcaaagatac
    30481 gatgcaagaa attcccgtga ctacgggcat caggacgcaa acgtaattcc tcctgcaagc
    30541 ctaaaacgta gcgtaggaaa taactgtatt cattgcgata aaactctgtc aaacccgacg
    30601 tagacaggta aaactcctgt ttggcaggat agagagcttg caaggtgtcc ttggctaagg
    30661 tcttgctgct tggactgatt gggatggctg gattttccag accttgctga tctagttttt
    30721 tacctatgac acgcgacaga accttgacaa aagtcaaatc ttgctcagta tcgctcatct
    30781 caccctgctg gtgataggca accagactag acaaaagact gtgataggac cccatatcct
    30841 ccttagacag tcctttgtga ttcatcctct tctctctccg cctaaatcca aaatggatca
    30901 actcttgaag ataggcagat tccttacttt cactttcgtt aaaaaggctt ggagccgaca
    30961 agaacaactg cttacgagca gaattgacca aggaaagcat agtgtagcga tttttcttga
    31021 gattttcact gctggcaatc agtaattgaa cgccttcttc ggtcgtttgg tttaggtttt
    31081 gcctttcttc atctgtcaga agactggtgt tttgagaaat ttttggtaaa ttgtcctgag
    31141 ttagtccaat agcatagaca aagtcagcag tcaatggtgc aatcaaatcg taactctgca
    31201 ccagaacagt gtccactgtt gctggaatgg tacggtattg ggacaaactc attccagaat
    31261 ggagcaaggc taggaagtct tccagactaa cctgtgaacc agcaaaaaca gtcgcaaatt
    31321 gttctaaaac atggcagaaa gccttccaaa cttcggcttg tctttcctgt tctacagctt
    31381 ccaaagtggt tgtcaaatct tgtaactgct tggtcacagc tccttctttt agaaagacac
    31441 tccatttttg taggaggttt tcagcctttt gttttcggct ggcaaagagg gtttcaagag
    31501 gtgctaaaat tctcaggcgg aggacattca aacgctcaag attaaatttt ccatggtggg
    31561 atttggtgaa agtttgctga aaggctggca agccattgat accaagatag cggatatatt
    31621 gctcaaaagc atcaatatca gactgactga ggtcagtata caaatcagtt ctaagaagat
    31681 taatcaaatc ctcctgacga aaacggtaac gttttaaagc taaaatagac tcgacaaact
    31741 gagtcaaggg atgatgagcc atggcttcgc ttctaccaag ataaaaagga atctgatact
    31801 ggtcaaaaat ggttttgaga gataactggt aagaagctac atcccccaag agaatacgaa
    31861 aatgcttgta gctcaggtct gagttctcat gtaatttctg acgaatgcta cgggctacta
    31921 gctccaactc ctccttttgc gtcaaacaag accagatttg taaattttca cggtctttct
    31981 catcgacatc caaagcgagt tctgaaaagt cataagaaga ctccaacaaa cgagaggcct
    32041 tgtcaaaact atccatcttc tcatgagttt gagaacagtc ctgagcaggc gtttggtatt
    32101 tagaagccag atgatggaga aattttacgc tggcttggta gagattgccc tcgctaaaag
    32161 gactggtata ggctttctta ctagcataag ccccgataac aatctcaaca cctttgccgt
    32221 gaagtaagtc cacaacccgc tcttcctcag cagaaaaacg agtaaagccg tcaatgacca
    32281 aggtgatttg attaaaatca ctacttacct tgtcattctc aatagcctca atcaaatggg
    32341 acaactgact tccctgggct aactgacctt gattaagata ggctgttact ttctcaaaaa
    32401 tcaagagtaa atccgccctc ttatcctcat ctgttaaatt ctccaagtcc aaaaaactca
    32461 tctgagattt ggtcatctca tggtaaagct caattaactg ctggatcaat tgaggatcct
    32521 gcttaatagc gccataaaca cgcaagtcct tgggatcgag ttcggcaagg catttgtaaa
    32581 aggccaaccc aagaccgata tcatcaagag tagttttaac tggtaaatca ttcaagacca
    32641 gataacgagc catttgagca aagcgcgtga cggtaatcga aaaagaagcc tgctgggaca
    32701 agcattccag cacggcgcgt tccttttcaa aagaaagaga gttgggggca atgtagaaga
    32761 cccgcttgcc agctgcaact agctcttctg cctctcttgt tagaatttct gtcaaagaag
    32821 ttcgaatatc agtataaagt aatttcatct cagcctcgtt ggaatttttc atcaccctat
    32881 attataccat gattagcctc gtaaatctgt taaaatattt aggccatcct ttcttttctt
    32941 catcatctgc taaatcttaa atacttagct ttacttgtat tagatagaat aagtctggct
    33001 actgaaaatc acataataaa aaagcctcgg taacaaggct ttgagtttta tgattgtttc
    33061 ttaggtacgg aatacacttc aatgtgttgt cccagtatct taatgtcgac tggtagattg
    33121 tctgatttat cgccatcaac atcggactct aattcgatat cagaagaagt tttaatatta
    33181 cgtgccttta tatattcaat attcttgata gaatgattga actatagtaa attgaaacta
    33241 taatagtaca ccgtggatgc taaaatattt ctagaaatta atttgatttc cctaatcaag
    33301 ctgttcgtat cttatttcaa tcta
//
LOCUS       DAVBEM010000021        32954 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVBEM010000021 DAVBEM010000000
VERSION     DAVBEM010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32954
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.021"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(498..1187)
                     /gene="rplA"
                     /locus_tag="VQ548_000999"
     CDS             complement(498..1187)
                     /gene="rplA"
                     /locus_tag="VQ548_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HET2653865.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMGLVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1394..1819)
                     /gene="rplK"
                     /locus_tag="VQ548_001000"
     CDS             complement(1394..1819)
                     /gene="rplK"
                     /locus_tag="VQ548_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HET2653866.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAVRMIEGTARSMGFTVID"
     gene            complement(1942..2658)
                     /locus_tag="VQ548_001001"
     CDS             complement(1942..2658)
                     /locus_tag="VQ548_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HET2653867.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKAKNEDGAAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     VIGTNGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYFGFEGGDYVD"
     gene            complement(2661..3131)
                     /locus_tag="VQ548_001002"
     CDS             complement(2661..3131)
                     /locus_tag="VQ548_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET2653868.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVSELHHLEKKTRIRFLEEMSVVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     RGDMNGYGLNGRGPVWWIPFEEMTAEICQSKPDEIKRLVERLSSEVDKLLEIKE"
     gene            complement(3133..4170)
                     /locus_tag="VQ548_001003"
     CDS             complement(3133..4170)
                     /locus_tag="VQ548_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HET2653869.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVLGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAMLLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTNEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLKSALVD"
     gene            complement(4268..5593)
                     /gene="brnQ"
                     /locus_tag="VQ548_001004"
     CDS             complement(4268..5593)
                     /gene="brnQ"
                     /locus_tag="VQ548_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HET2653870.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(5764..5856)
                     /locus_tag="VQ548_001005"
     CDS             complement(5764..5856)
                     /locus_tag="VQ548_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2653871.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(5899..6051)
                     /locus_tag="VQ548_001006"
     CDS             complement(5899..6051)
                     /locus_tag="VQ548_001006"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2653872.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(6211..6789)
                     /locus_tag="VQ548_001007"
     CDS             complement(6211..6789)
                     /locus_tag="VQ548_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HET2653873.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPCT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(6843..8243)
                     /gene="pepV"
                     /locus_tag="VQ548_001008"
     CDS             complement(6843..8243)
                     /gene="pepV"
                     /locus_tag="VQ548_001008"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HET2653874.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLTDLQAKLDAFVAEHKLRGELQEEAGQYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8256..8861)
                     /locus_tag="VQ548_001009"
     CDS             complement(8256..8861)
                     /locus_tag="VQ548_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HET2653875.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDLKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            9032..9832
                     /locus_tag="VQ548_001010"
     CDS             9032..9832
                     /locus_tag="VQ548_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2653876.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(10014..10847)
                     /locus_tag="VQ548_001011"
     CDS             complement(10014..10847)
                     /locus_tag="VQ548_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET2653877.1"
                     /translation="MNHKIAILSDIHGNATALEAVIADAKTQGASEYWLMGDIFLPGS
                     GANDLVALLKELPITASVRGNWNDCVLEALDGQYGLEDPQEIQLMRMTQFLMERMDPA
                     TTVWLRSLPLLEKKEIAGLRFSISHNLPNKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(10837..12684)
                     /gene="uvrC"
                     /locus_tag="VQ548_001012"
     CDS             complement(10837..12684)
                     /gene="uvrC"
                     /locus_tag="VQ548_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HET2653878.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGIHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQRKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            complement(12724..13425)
                     /locus_tag="VQ548_001013"
     CDS             complement(12724..13425)
                     /locus_tag="VQ548_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HET2653879.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKMGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(13504..14736)
                     /gene="murN"
                     /locus_tag="VQ548_001014"
     CDS             complement(13504..14736)
                     /gene="murN"
                     /locus_tag="VQ548_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HET2653880.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(14741..15961)
                     /gene="murM"
                     /locus_tag="VQ548_001015"
     CDS             complement(14741..15961)
                     /gene="murM"
                     /locus_tag="VQ548_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HET2653881.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16073..16852)
                     /locus_tag="VQ548_001016"
     CDS             complement(16073..16852)
                     /locus_tag="VQ548_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET2653882.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(16921..18582)
                     /locus_tag="VQ548_001017"
     CDS             complement(16921..18582)
                     /locus_tag="VQ548_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET2653883.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPEHIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKILSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(18757..20979)
                     /gene="recJ"
                     /locus_tag="VQ548_001018"
     CDS             complement(18757..20979)
                     /gene="recJ"
                     /locus_tag="VQ548_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HET2653884.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKTYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21256..22014
                     /locus_tag="VQ548_001019"
                     /pseudo
     CDS             21256..22014
                     /locus_tag="VQ548_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            22054..22818
                     /locus_tag="VQ548_001020"
     CDS             22054..22818
                     /locus_tag="VQ548_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET2653885.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTELLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            22831..23508
                     /locus_tag="VQ548_001021"
     CDS             22831..23508
                     /locus_tag="VQ548_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2653886.1"
                     /translation="MIDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILAHIFVEFYQNTPLLVQFVIVFYGLPLISDHTIMIPIYWTAVLCMGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQTFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            23518..24177
                     /locus_tag="VQ548_001022"
     CDS             23518..24177
                     /locus_tag="VQ548_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2653887.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNTVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLCILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            24472..25662
                     /locus_tag="VQ548_001023"
     CDS             24472..25662
                     /locus_tag="VQ548_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HET2653888.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(25983..26864)
                     /locus_tag="VQ548_001024"
     CDS             complement(25983..26864)
                     /locus_tag="VQ548_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HET2653889.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(27005..28333)
                     /gene="vncS"
                     /locus_tag="VQ548_001025"
     CDS             complement(27005..28333)
                     /gene="vncS"
                     /locus_tag="VQ548_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HET2653890.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGATMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(28330..28986)
                     /gene="vncR"
                     /locus_tag="VQ548_001026"
     CDS             complement(28330..28986)
                     /gene="vncR"
                     /locus_tag="VQ548_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HET2653891.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASIAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(29035..29118)
                     /gene="pep27"
                     /locus_tag="VQ548_001027"
     CDS             complement(29035..29118)
                     /gene="pep27"
                     /locus_tag="VQ548_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198524447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HET2653892.1"
                     /translation="MRKEFHNVLSSGQLLADKRPARDYNRK"
     gene            complement(29298..30677)
                     /gene="vex3"
                     /locus_tag="VQ548_001028"
     CDS             complement(29298..30677)
                     /gene="vex3"
                     /locus_tag="VQ548_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HET2653893.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(30729..31376)
                     /gene="vex2"
                     /locus_tag="VQ548_001029"
     CDS             complement(30729..31376)
                     /gene="vex2"
                     /locus_tag="VQ548_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HET2653894.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKDTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31389..32666)
                     /locus_tag="VQ548_001030"
     CDS             complement(31389..32666)
                     /locus_tag="VQ548_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2653895.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITSYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9304 a         7548 c         6127 g         9975 t
ORIGIN      
        1 tcggcatacg gcggttcaac taactgttaa cgcatgtcgt tcaaggtaat aatccaaaca
       61 cgaaaccagt ccacgttttt caaggactgg ttttgatata gcacgtttaa gtaccgactt
      121 ctgagctact atagtagatt gaaactagaa tagtacatct cttcttctaa aacattgtta
      181 gaaatcgatt tggctgccct gatcgattcg tcctactctt atttcatttt actataattg
      241 atagtggtcg ccccagccag ataccttatc cgctatatag gccttattat catgttcctg
      301 ttcgtagagc cacgatttcg ctatcccttc ctctgacgat tcttatttcc tgcgtcagac
      361 ttgggaatcg ctattgggtt caccggtagc aggtgcccac cgaggactta cacctcagat
      421 atacgacatg cccgtcgtac atcaaaaaaa gttgagacat agcgtcttca acttttttac
      481 attactttaa ctactgatta aagtgagttt acgtcaactt tgataccaac accttgagta
      541 gttgtgatag tcaagtttgt tacgtaagtt cctttagctg tagctggttt tgctttttgg
      601 attgtttcgt tgaaagcttt aaagttttca accaattttt cagcttcaaa tgatacttta
      661 ccgatgattg cttgaacgtt acctgcacgg tcagcacggt aagtgatttt accaccttta
      721 gactcttcaa ctgctttagc aacatccatt gttacagtac cagttttagg gtttggcatc
      781 aagttacgtg gtccaaggac acgtccaaga cgtccaacaa gacccatcat atcaggtgta
      841 gcgataacta cgtcgaagtc caaccaaccg tcgttgattt tagcaacaag gtcatcttca
      901 ccaacaaagt ctgcaccagc agcttttgct tcttcagctt ttgcaccacg tgcgaaaaca
      961 agaacgcgtg aagttttacc agtaccgttt ggcaatacca ttgctccacg gatttgttga
     1021 tcagcttttt taacgtcgat gttcaagttg taagcaactt ctacagttgc gtcaaatttt
     1081 gcaaagtttg tttcttttgc aagtgctaca gcttcttcta cgctgtatgc ttttgtgctg
     1141 tcgattttct caagagcagc acgaagttgt ttgctttttt tagccatttt ctattctcct
     1201 tgtaagtggt tcaatcgatt ttcatctccc acgtcacttc tcgaaatgat gaagtcttgc
     1261 gggttttcag tctattagat tcttttccta cggccttaag ctcccttgct gtacccaagt
     1321 acaagcatca gtcacttgcc tagtatgaaa agcaactaat agactgctgt gagattttct
     1381 actgtgttat tgattagtca ataacagtga atcccataga acgagcagta ccttcgatca
     1441 tacgcactgc agactctacg tttgctgcgt tcaaatctgg catcttagtt tctgcaattt
     1501 cttgtacttg tgcacgagta actgtagcaa ctttagtttt attaggtgta cctgatcctt
     1561 tttcaacacc tgcagctttt ttcaaaagaa cagcagctgg tggtgttttc gtaacgaaag
     1621 taaatgattt atcttcgtaa actgagataa caactggaat gatcatacca gcttggtcag
     1681 ctgtacgagc gttgaactct tttgtgaatc ccatgatgtt gataccagct tgaccaagag
     1741 caggtccaac cggtggagct ggtgtagctt taccagcagg gatttgcaat tttacaagtt
     1801 tttcgacttt tttagccatt tttaaatcct cctttgtggt tttggcggta attagagatt
     1861 tttacctccc acaagtatgt ttttcacata cccatctatt atacactatt tatctggaat
     1921 tgcaagagaa aagtttattt tttaatcgac gtaatctcca ccttcaaagc cgaaatactc
     1981 ttccaaactg aggccactag ctgcaatctc tttagcctct tttccgacat aacgaaggtg
     2041 ccattcctca gccatatagc ctgtttcctt ttccttacct ttgagataac gtacaacaaa
     2101 gccataatca gccgcatgat ccaagagcca ttgggccgct ttttcttctg tcaccaaatc
     2161 accatttgtc ccaatcacat caaaggctaa acctgtctgg tgctcgctat agccaggacg
     2221 ggcagaataa cggtcggcag cttctttccc atcttgattg acataatctt gatagagctt
     2281 ggtctgagtt tcataacttc taaagccact gtaatgatcg ctaatgggga aacctgcctc
     2341 ttgcatagct ttgatgagct tgaccaactc agccttggct gttggatttt cccctggatt
     2401 gtagtctttt gacaatggat agtgtttgtt ggctacgatg atttcatcgt atttcccttg
     2461 aatgctgtaa tagtctcctt tgttaaccac ttctgctttt ttctgggcag ctccttgaga
     2521 cttacttcct actgttccat cagctttagc agtttgctct gtcttagctg ctccatcttc
     2581 attttttgct ttttcttgtg aacaagctgc tagactcaag gctagcaagg ctgtcaagac
     2641 aaggtatctt tttttcatct ttactccttt atttctaata gtttatctac ttctgatgat
     2701 aaacgttcga ctaatctttt aatctcatca ggttttgatt ggcagatttc tgctgtcatt
     2761 tcttcaaagg gaatccacca tactggacca cgtccattga ggccataacc attcatatca
     2821 cctcttcgtc taggaaacag atgccaatgg agatgagcat cgccatttcc tagtagttcg
     2881 atattcattt tctcagcagc aaaggccttg gcaactgcct cttggaccac actcatttct
     2941 tctagaaaac gtattctagt tttcttttct aaatgatgca attcgctgac atgttccttg
     3001 gctagaaaga gactatagcc tgcaaaatac tggtggtctc caatcacaag atagcctgtt
     3061 tccaactctt tgacaaaata gggattttct cccttcttga tgagctcaat tctctggcaa
     3121 atcaaacaca tattagtcta ccaatgcact cttaagatag gcatcgacca ttcgttctgt
     3181 tgcgaccacc gagtcaatat gagtgcgctc ataagaatga ctagactcga tacccgcacc
     3241 aagaagggca tgcttgacct ctgcccctgc agacatagcc gctgaagcat ccgaaccata
     3301 aaatggatag atgtccagct taaaaggaat atcttgctct ttagccaagg caaccaagtg
     3361 ttgacggaag tcatagtgat aaggacctga ggcatccttg acacagatag atactgtgta
     3421 ctcatttgtc tgctggtcat ctcccatagc tcccatatcc acagccagat attctactac
     3481 ctgagcagga atgttagaat tagcaccatg tcctacttct tcaaaaactg aaaaagcaaa
     3541 atgagttgtt actggcaatt caatcttctc tttcttataa atacgaagca ggttgagcaa
     3601 catcgctgcg ctgaccttat catccaaatg acgagacttg ataaaacctg tatcagtcac
     3661 aacagttcgt ggatcgaagc tgataaaatc accgacctca atcccaagag cacgagtttc
     3721 tttttcattg cttactttta catccaaacg cacttccata ttgtcctgcg tgcgttctgc
     3781 agttcctgca tccttgtaga catggcaaga agtttggtgg atgaggatgg ttcctaatac
     3841 cttttgacct gtgctagcca catgaacggt acagttttca ccttcaatca tgttccaagg
     3901 aaaaccaccg atacggtcca atttaagacg accatctggt ttgacagcac gaacaatagc
     3961 acccagtgtg tccacatggg cagtcacata gcgatgttgc tcatcatttt gacctttgat
     4021 ggtcacattg acaccaccct tggctgtgcg aactggctgg taaccaaaac cttctagagt
     4081 cttgactaaa taattcgaaa tttcacgagt gaagcccgtt ggcgatgcga tggctgtcag
     4141 ttctttgata tattctactg tttgattcat ttcttcacct ctttcgctac ctattataac
     4201 acatttatca tcggataaaa aaagaaaatc actcctgtag acttggctac aaaagtgatt
     4261 taagtgatta ttccatttca aaaacatcgc tttcttgctt gtttggtaga accaatgaga
     4321 gcaagattcc aacaatggct ggcaccaacc atgggagaga tgccttggca aaaggaagaa
     4381 cgctaacaag atttgcaaga aactcaacct taaacgagct tcctagtacg cttgcaatgg
     4441 caataactgt aaccacagca attgtcaact gcatacctgg ttttgaaagg gcaacaaatt
     4501 tgttgacaat gacaatcata acgatagcaa tcgtgattgg gtacaagata accagtactg
     4561 gaattgagta cttgataatc gcatcaagac ccaaattggc aatagcaaat ccaatcaagg
     4621 taaaggctgt cgcataaacc ttgtagctga tttgtgggaa gcgctcatta aagaactcag
     4681 ctgttgacac aatcaaacca acagtcgttg tgaagcaggt tacggtaacc atagctgcaa
     4741 ggaagagttg agctgttgag ccaaagattt cttgagtggc ttgtgacaag atgtaaacac
     4801 ctggtgttcc acccttcatc gcttcagctg gtactgggaa atgatttcca agaaaaccta
     4861 aaccgatgta aagagcgctg aaggcaaggg caacaacgat accaacaacc caaatagttg
     4921 aaatgtattc tttcttactt gaaaatccaa gttgtttcaa ggtttgaact gcgattacgc
     4981 taaaggccac tgaggcaagg gcgtccaagg tattataacc ttctaggaaa cctgtaccaa
     5041 aggcagaagc ttgataagca gctgaagcag cttgaggact tgttccacca tatttgatag
     5101 ctcccagaac gaccaagata acaatcaaaa ttgcaaagac tggcgttaaa atacgtccaa
     5161 tgcggtctaa gatttttgat ggattaagcg aaatcaaata ggctgccgca aaatacagaa
     5221 ccgtaaatac aatcaagcca agtcctttat ttgcatccga caaaaggggg ctaatcccta
     5281 cttcgtaagc tgttgtagca gtacgtgggg tagcaaagaa tggaccgatt gacaagtaaa
     5341 gaactgagag gtaaagagtc gcaaaccaag gcgctatctt cgttgaaatc tcgtagatat
     5401 atcctttagg atttagcgtt ccaataataa gggtcaagac ggcgatacca acgcctgaaa
     5461 agacaaaacc tgcgatggca ggaagaaaat gttctccaga tagagcacct agagaaggcg
     5521 gaaaaatcaa gttccccgca ccaaaaaata ttccaaacag gagcaaacct gttagggtac
     5581 cttttttagc cataaaaatc tccttcatat ttataaaata ctgatctagt ataccacgat
     5641 taggagtctg aaaaaagcat cacgaggcaa atattaaatg ttttcaattt tcttaaaaat
     5701 aagaattatc taaaaataaa actctcctac ccagtccaca ccaagtagga gaaatgcaaa
     5761 attttaaagt tcttcaaagg ctaacatgcc accctggaca ttgataacat tataaccttg
     5821 ttctaatagg aattggcaag cacgcgccga tctcattcca gatttgcaaa taatataatg
     5881 caagcgatct ttgtccaatt aatcataact atcagccaat tgactaagcg gtaggttgtg
     5941 ggcaccttct aaatgaagag ctgcaaactc atccacttct ctcacatcca ctagagaaag
     6001 ctggtcgttt tggtaaagct ggtaaaatgc gtcaaaggct atttctttca ttctttttct
     6061 tctaatactc ttcgaaaatc tcttcaaacc acgtcagcgt cgccttaccg tgcgtatgtt
     6121 accgacttcg tcagttttat ctgcaacttc aaagctgtac tttgagcagc ctacgactag
     6181 cttcctagtt tgctctttga ttttcattga ctataaaatg gttttaattc tttttttcaa
     6241 atctggcact acttctgcct caaaccaagg atttttggcc atccagattt gatttcgtgg
     6301 tgatgggtga actagcggaa aataggctgg cagatagtct ttatagtgtt tcaccctctc
     6361 cgttaccttc ccactgattt tctcctgtaa atagtaggct tgggcatatt gcccaatcaa
     6421 gagggttaac tgaatatcag gcaattcctg taagagctgc ggatgccatt tttctgcaaa
     6481 acctgtacaa ggcggaagat cacccgactt gccatgtcct ggaaagtaga aatccatagg
     6541 caaaacagca aaataacctg aattgtaaaa ggtatcttca tccacaccta gccagtcccg
     6601 caaacggtca ccacttttat ctttccagta aaggcctgct tcttgagttt taagtcccgg
     6661 agcctgaccg atgatattga tgcgagcagt ttttggcgct gcaaagagag gctcaatgcc
     6721 acgctctgta tagctggcat tctgcgaatc cgccatgata gcctgtttga ttctttcgat
     6781 ttgagacatc tactttccct ccaaaaagaa gtccaagcat aagatctcag acttctatcg
     6841 ttttatttga tcaattcgta aatagcttcg gcataaattg ctgctgctcg gaagagatcg
     6901 tccaaggcaa taaattcatt ggcttggtgc atggtatcaa ttgagtctgg gaacatagca
     6961 ccataggcaa ctccgcgctc taacaagcga ccaaaggttc caccaccgat gacttgttca
     7021 tgacctttaa ggcctgtttg tttttcatag acattcaaca aggtttgcac aagtggatct
     7081 tccattggca catagtgagg ggtatgacca tgttctgata gactgacaga agcaactggc
     7141 aagttttcta ggattgactt gatttgttct ggacttgttc cttttggata gcggatgtta
     7201 agggcaatgg tattatcagc acttgtttca tcgaagcgga agacgccggc attcatagaa
     7261 agagcaccca tcttttcatc cacatgagca atcttgagat tttcaccctc atgatcgttc
     7321 aagagaattt tacctgcgat gtcaaggtag tctttggctg gaccagcaaa gccaaactgg
     7381 ctgaggaaga gggcaaggta agttgcgcca ttgacacctg aagcaggcat agcaccgtgg
     7441 gctgatttac caatgatcgt caccttgtat tggccagctt cttcttggag ttctcctcta
     7501 agtttgtgtt ctgcaacaaa ggcatctagt ttagcttgca agtctgtcaa gtcacctgaa
     7561 acgactgctg ttgctgattc tggtaccata ttttcacgta aaccacctgt aaagctgtga
     7621 agacgggctg cacctgtatt ttcacctgca aagtggaggt attccgtgat gtttcctttt
     7681 tcaccattga tgattggaaa ttcagcatct ggtgagaaac caaagtctgg cttggcgagt
     7741 cctacgtgct cgaagtagta gtccatatct gcccagcctg attcttcgtc tgttccaacg
     7801 atgaagcgaa ctttcttaga agttggaagg cccaattctt tgatgatttt caaaccatag
     7861 tagcaagctg ttgtaggtcc cttgtcatct gaagcaccac gcgcataaag gcgaccatct
     7921 ttgatagttg gtgtgtaagg gtctgtgtcc caaccgctac cagctggaac cacgtccata
     7981 tgggcaaaga ttccgagaac ttcttctcca tcaccaaact caaaatgtcc tgcatagtta
     8041 tcaacatttt tagttggata accatcacgg tctgcgattt caaggaattt ttccaaggct
     8101 tttactggac caggtccaaa tggatgttgg gcatcagcct tgctatcatc acgttctgag
     8161 ttgatttcca aaaggctaaa caagtcagcc aagaggtctt ctttgcgttt ttctacttct
     8221 gctgtaaaat caattgctat cattttttct tcttcctatc ttttttcgat gatttcatct
     8281 actggcaagc ggtagcttgg ttccaatttg tcgtctgtgt aacccactgt gatcaagagt
     8341 tctgggcgga aacggtcttc aatttccaaa acctcattga cttttgattt gtcaaaacca
     8401 aggataatat tggaaccaat tccttggtct gtaagagcga gaaccaagtt catagcaacc
     8461 aaacctgcat tgagtgctag gtagtcgctg acttgttgtt cattgtagcg tgcaaattca
     8521 gctggcaaat ttttcatgaa gtattgaagt tgttcttctg agaaattgtt agcaccacca
     8581 actcgggcaa tcttacgagc gcgtttggca aggtctgtat ctgtaaatag ggcaatggtt
     8641 acaggtgctg atgatacctg ctcaaagttt gaaccataag ccaactttgc cagttcagca
     8701 tttttctcac gaacaactac aaatttccaa ggctggctgt tgtgggcgct tggcgccaag
     8761 gttgcaattt cgatagccgt acgcacatct tttagatcaa caggcttatc agtgaaatgc
     8821 ttggtcgcat gacgtttttt atttaattca agaaatttca taatcgattt ccttttctaa
     8881 ttctactgct tccattctac cataatttga aagagcttgc agggattttt catgattaag
     8941 tttttctatc acagacataa aagatatata ttggtttatc aggaaagttt ctgataaact
     9001 agcaagtact ttacatttga atggagacag tatgaaaaaa tttagcctat tactagctat
     9061 cctaccattt ttggttgcct gtgggaatca agctacaccc aaagagacta gcgctcaaaa
     9121 gacaatcgtc cttgctacag ctggcgacgt gccaccattt gactacgaag ataaaggcaa
     9181 tctgacaggc ttcgatatcg aagttctaaa ggcagtagat gaaaaactca gcgactacga
     9241 gattcaattt caaagaaccg cctgggaaag tatcttccca ggacttgatt ctggtcacta
     9301 tcaggctgcg gccaataatt tgagttacac aaaagagcgt gctgaaaaat acctttactc
     9361 gcttccgatt tccaacaatc ccctcgtcct tgtcagcaac aagaaaaatc ctttgacttc
     9421 tcttgaccag atcgctggta aaacaacaca agaggatacc ggaacttcta acgctcaatt
     9481 catcaataac tggaatcaga aacacactga taatcccgct acaattaatt tttctggtga
     9541 ggatattggt aaacgaatcc tagaccttgc taacggagag tttgatttcc tagtttttga
     9601 caaggtatcc gttcaaaaga ttatcaagga ccgtggttta gacctctcag tcgttgattt
     9661 accttctgca gatagcccca gcaattatat cattttctca agcgaccaaa aagagtttaa
     9721 agagcaattt gataaagcac tcaaagaact ctatcaagac ggaacccttg aaaaactcag
     9781 caatacctat ctaggtggtt cttacctccc agatcaatct cagttacaat aacactcttc
     9841 gaaaatctct tcaaaccacg tcagctttat ctgcaacctc aaagctgtgc tttgagcaac
     9901 ctacggctag cttcctagtt tgctctttga ttttcattga gtataagata tactaaaagc
     9961 gattggacca gccaatcgct tttttagttt gcattggcta ttttaggaaa ctcttacaaa
    10021 aaatcaaaaa aattcttcac atcctctaca tacccatgct tttctattaa gctggctaaa
    10081 agttccagat tgtgcccctg atagttatcg tcacgacgca gttcttcata catttcaata
    10141 aagggaagcc ccttggactt ggccaattct aactcagcct cgtaatcata agcaacttta
    10201 cgaaattgga tattgaccaa ttccccatct tcaacttcta tcacggcata ctgggcacgg
    10261 tgatttttta acgcctccca attaaaatag ggcatgccaa tcgaccctgg attgatgatt
    10321 tgttgccctt gacttccata acgaagcaac tgcttgtgaa catgaccata aactgccacg
    10381 tccgtttccg catctagcag ttggtcaaat ttctctgtat cattctcaac tagcaagtca
    10441 ccaccatagt tcttatttgg caaattatga gagatagaaa agcgcagtcc agcaatttct
    10501 ttcttttcca gcaaaggcaa gcttcgtagc cagacagtcg ttgcaggatc cattcgctcc
    10561 atcaaaaact gagtcattcg catgagctgg atttcctgtg ggtcttctaa gccatattgc
    10621 ccatctaaag cctcaaggac acaatcattc caattgcctc gaacacttgc cgtgatagga
    10681 agttccttta acagagcgac caagtcattt gcacctgaac cagggaggaa aatgtctccc
    10741 atgagccaat attcactggc tccttgagtt ttagcatctg caatcactgc ttctagcgcc
    10801 gtcgcattgc catgaatatc tgataaaatt gcgattttat ggtttattgt ggtttccttc
    10861 cgtttggtaa tctactcttt cttccgccac ttgaagcaag atttctgttt cctgcgggtt
    10921 caactttctt tgcacagcct ctgctactgc tcttggtact ccaacttcga caatctcatc
    10981 cacactggct tccttgattt tggtcagaga cttgaagtgc ctcatgagat tttgcttgcg
    11041 tttaggtccc agaccatcaa tcccatccaa ttgagatgag aaagaatttt tggagcgcag
    11101 ttggcggtgg aaggtaatgg caaagcggtg gacctcatct tgaatgcgtt ggaggaggaa
    11161 aaattcctga gaattgcgag acaagtccac cacttccagc ggatctccaa agagcaattc
    11221 atgggtttgg tgcttatcat tcttttgcag acctgcaatt ggaatatcca agcccagttc
    11281 ttcttggatg acttgcttag caatattgac ttgaccttgc cccccatcaa tcacaatcaa
    11341 atctggagga gtcaaagcct cacgctgtac tcgaccatag cgtcttcgaa tgacttctct
    11401 catactagca tagtcgtccg gcccaacaac ggtttttatc ttgtacttac ggtaatcttt
    11461 tttacttggc ctgccgttaa caaagaccac catggctgaa acaggactgg tccccatgat
    11521 gttggagtta tcgaaggact cgatgcgaac tggagtcgga atttggagca aacgtcctag
    11581 attttcaata gctccttggg tcttttcgac tgatttttct agcaggttaa atttctgctc
    11641 cagactaaca cgtgcatttt ttatggctag attgaccagc tgttttttct ctccacgttg
    11701 gggtttgaga atcttggtat ccaccaaagc cttgacagct tcttcgtcaa tatcctgcgg
    11761 aatcagtacc tcattgggaa ctaggtgaga tttttcttga tagaattgtc ccacataggt
    11821 caagaaatcc tcatctggat cattgaagta ggggaagaga ttgacatcgc gctcgatgag
    11881 cttgccctga cgaacaaaga aaacctgcac acacatccag cccttatcca catagtagcc
    11941 aaagacatcg cgattttgga gatccttagc catgacccgt tgcttggttc gaagcgttcc
    12001 aatagcctga atcaggtcac ggtattccgc cgcacgttca aactccatac tttgtgctgc
    12061 tactgccatt ttactcttga gatcatcgat gattttgtca tcctgacctt tcagaaaatc
    12121 agacacctcc tgagccatag acttgaaata agcctcatcc ttcttacaga tggtgtgggc
    12181 catacactgg ccgatatggt aataaaaaca gaccttagag ggcgggttgg tacattttcg
    12241 aaaagggaaa atcctatcta gaagtcgctt gatttcattg gctgccccca catctggata
    12301 agggccaaaa taaagaccac cgtccttttt gacctgacga gtaatgataa gccgtggata
    12361 gcgctcattg gtgattttga tgaaaggata ggacttgtca tccttgagca tgatattgta
    12421 cttgggctta ttttccttga tcaagttgat ttccagcaga agcgcctcaa tattggactc
    12481 agtgacgata aattcaaaat ccacaatttc agacaccaga gcctctgtct tggtatcatg
    12541 aattccacga aaataggacc gtactcgatt acgcagattt ttagcctttc ctacatagat
    12601 aatggtgcca tttttatcct tatgaatgta gcaaccaggg ctggtcggca agagctctag
    12661 ttttgattta atcaagttgt tcatagttcc attatagcaa aaaaagtagg gaaagatagt
    12721 accctactca ctagtctcat atatttttcg gaggtttgca acatcctctt cctggatacc
    12781 ataaaaggaa cctgctggtt gcatgacaga cttctcatct gtatggtcca agccaatcgc
    12841 atgacctaac tcatgttctg ccgtatggac aaggcgttca taggagtagc catagtatgg
    12901 attggacaaa taataatgat tcaaccgcac cgttacggac aagaattgcc ctgttaagag
    12961 attagtttga ctttccgcct ctcctgccac aggagtgcct ccgtcgttca tctccgtagc
    13021 cgtaatatcc gccttactag actcagtcac gagttcaaag ttaaaagcac cagtttgatt
    13081 ccagttctgg attgcttcta aataagcctc ttgaaagcgt gaatccatct gcggatccag
    13141 gtaaatacga gcagaggcct gtgcccacct tccttcagaa tgctggtgac tatctgtctg
    13201 gcttaactta ggcagttgcc ctgttttctc ccattggtca atactttgtt gacccatttt
    13261 tactgaccgt tctgcttgct ttagcgctcc ttgaaaatcc ccgttcagat accagagaag
    13321 tccgaaagca agcacacata agagcacaac tatccaaacc agacgccaaa acaaacgcca
    13381 cacaaaagaa aagaaagccc ctatcaaacg aaaaagccag cgcatgtctc tccacctttc
    13441 tagcaaataa gaattatttt actaaaagaa gctaaaagaa atctaaatac tgactttttc
    13501 atcttaacgt cctactattt ttttgagtaa ctggatagct ttgtatttta aaggcgatgg
    13561 atggtaacgg aaagtacctg ctttgcgtac aatatagcca ttaaaattct gtttaaaacg
    13621 caaaacacca tcacttccat caaaaatccc ttgaatgcct aggaagttgt atttaggtat
    13681 tccacgtttt atgctttcca acataacata tttttgaagc agtgcagggg catagaactt
    13741 attaaactca gtgtaggaac cactaaagag ataagtcgtt tcctgaggca tataaacaaa
    13801 taaactccca gctaaaacaa tatcttcttc tccatatttt tcaatcaagt ctcgcgcttc
    13861 tgcttttcga acttcaaacg tttcaaattg actagaatat tctctcagtt gattttgttt
    13921 tttctcagaa tgaggatttt tactcaaatc aagtcgcaac ttgtccaagt tttcttctag
    13981 tttactttgt tcaccttgca atttgctcat atactccgaa aaattcaagc ttgctatgag
    14041 aaactccgct tgttctccaa aagtatcata aaaatgctca taatattcta aacttttatc
    14101 actatattct ctacgttcag aggtttcttt tgttatattc ttaaaaatcg atagttcttc
    14161 acgttttaac tttttcaacc gaatgccaaa ggtttcagcc tttttcacca agggtttacc
    14221 ctttttgcta aaacttttaa gcaaactctt ttcagttaat tcagttaaat ctttatagta
    14281 taaccaatct ggttctccac ctgggtaacc tgttgttaag ccatcaaatt gataacctaa
    14341 atcagtcaaa ccttgaataa tacttttttt ctcagcatct attggattac cttggctatc
    14401 aaaagtttga taagtttcat aaggttttac aagcaactct aatacaccat tttgcttggc
    14461 atattctttt aactctgcat aaaaaactgg aagagcatct tgttgggtat aaatcggccc
    14521 cgaattgagt tccatatgca gaccacccag catgggcaag ctataaacca gagctgcaac
    14581 ttgaatttct ccttcttgtt tcaaagcaag ataaacaatt cgagcccctc ttttttctag
    14641 caaatccccc atctggacag attgcataaa ggaacgagaa gaaacctgat cagaataagt
    14701 ctgaaactct tctttcgtga gtgttgttag tgccatatac ttactttcta tgtttttttc
    14761 ttaatgtttt acggaaatca agagcaagtc ttaacagagg atagagagga tgagtgggca
    14821 ttgtaaattc acccaagtat tcttcaatcg ttggattaaa tttttcctta aaatgataaa
    14881 gtccaccatt gagagagttt tcaacaccac ctaaattttg ccagaccata cctcgctcaa
    14941 aggcatagcg agccgtttca taccatgtta aaattggtgc attgtaacgt ttaaaatcat
    15001 catccatacc agcatatata ttgacagagg tagtaccaaa ttccaaactc aaagtagccg
    15061 ctaaaggaac tctcgcttga cctacatcta tatattcctg caagaaggtc aattcctcta
    15121 acaaacgttc tttttccttc ttctgcgctt ctacttttga agttcgagtc gactcagtaa
    15181 aggtctcttc caaggctcta tttttcgcta actgttcttc taactcttgc gaacgtttag
    15241 aaacatccaa ggtggccaag gtgatatagg ccttgtcctt aaaattatct aacaattttt
    15301 tataataggc ttcattcctc aaatgaatct cttttcgctt ctcagttttt ttcatcaact
    15361 ccgaaaatga atctaatagt tccagtccac catattgaat ctcaagccct ttgtttcgtg
    15421 ctgttcgaat agcctgtttt gttgacttgg aaagtttatc ttcttcaaaa ttttccttgt
    15481 atattttcgc ctgaatacga ggttgaatgg tgtctcccat ttcctccgtt tttcctgacc
    15541 accttactcc catttgttgc aaactatcaa taatagccag attttcagga aattctgtct
    15601 tttcctgatt gattaaactt tgagataggc aaatacttgg gtcaaaagtc acaaaaaccg
    15661 ctctcttact gcgagcatag gacttaatag actgaatggc aaaattcaag agttctttat
    15721 ccccataatc caatataggt cctcttggga tgtaaaacat tttatagcct agcggaagag
    15781 ttctaatcaa aatactagct gtcgccagta atttttcttc cctgtaaaca ccaaacttct
    15841 catgttgcca attagactta acttcctccc aagcactact ttgtaataca ttggctaatt
    15901 catgttcttt gacaaactga tcatattcta atgtgggaat gccaatttga taacggtaca
    15961 tttcctactc tctttcctcc agtattttat tactattcta ctactttcgt ttgaaaagtc
    16021 tagtgaaaac atattttatt ttagttctac tccccctatg ctgaagttca aactaagtca
    16081 gtctctcttc taatttgaaa tcaattggta gggttgttaa aaaaacttcc aattgttttt
    16141 cccagtagta ccactcgtga gttccagcgc tatggctata ggtcacatca aaacctagtt
    16201 ttttgagatt tttcactgcg agattattgg cttcgtacaa gaaatcctgt tcgccacacc
    16261 acgcccaaag tttggtcttt ttatccgatt ttttagccag actttcaaga gaatagggac
    16321 tagttgtcca gtctctaatc tctccaaaaa cacctctcca gtaggctgga cttcccagat
    16381 tttgactttc aggagaaaag ttttgaaagc tgagggcacc tgaaaaacta gctgcatgag
    16441 aaaaacgatt tgtcgcaaga gccagtttga agcagccgta acctcccata gaaagaccag
    16501 cgataaaggt cttttcacgc ttgctagtca tattagggaa gaagcgtttc agaacctgtg
    16561 gcaattcctc tgctagagcc gtgtagtagt caaaaccata ctgggtatcg gtgtaccaac
    16621 cattgctggt attgggcata acaacgatga gattagttcc tcgaagcaag cgttctacat
    16681 tggtccgctt aagccaacta ttatgatttc cagacatccc gtgcaaaagg tacaagacgg
    16741 gaatatcttc acactctggt tcttccactc gattggcatc agggtagagg acattcaccc
    16801 cccactccat atccaatact tgtgagtaat actcgatttt cattactgcc atgattttct
    16861 ccttctattt ttctataaga aaaagccgaa actcgacttt ctctctgttt atttcaacga
    16921 ttattttgct tccatgacta ctggtaaaat agctggacga cgcttggttt ggtcaaagag
    16981 atacttggtc aaattatctc gaaccttccc tttaagatct gcccagtcaa agtcatctcc
    17041 ttgaagataa tcttctaccg tttggttaat caattctgaa ctttcacgga gaatatcgcg
    17101 actcttcttg agataaacaa atccgcgcgt atgaacacga gccctagcca caattttctt
    17161 ctcacgacgg ttgactgtaa tagccacgat gaaaattcca tcctctgaca agatcttacg
    17221 gtcacgaaga acaacatttc caacatcacc aatggcattc ccatcaatca agatatctcc
    17281 tgctgaaacc gatccagctg gaacaaagtc tccattctcg taagccatgg tcgtcccctt
    17341 tttaggaatg aagatgtgtt ctggcaacat cccaactgcc atggcagcct tagcgtgagc
    17401 atccaactca cgatactccc cttggacagg gaagaggtac ttaggttgca aaagattgat
    17461 catcagctgc aaatcacgca catttccgtg ccctgataca tgtaaacttt gggtaatcaa
    17521 tttgacaacc ccacctgcct gataaatcat attttccaca cgcgcaacaa aggcttcttt
    17581 agcaatagac ggagccgtag caatatagac caggtcccca tccttgattt ctacataacg
    17641 atggcgacca atcgacatct tacgaagtcc attgataggt tcacccatac gacctgtctc
    17701 aagaataatc aactcatggt cttcaaagcg agacatatct ttaggcttaa tcaagagaat
    17761 ttcgttggct aaagacaact tcttaagacg aatcgctgtg cggacgatat tttcaatatc
    17821 aaatcctgtc aagacgatac gtcgacctgt tttatccgca gcgtcaaaaa tctgctgaat
    17881 acgagaaaga ttactggaaa cagctgcaac gatgatacga ccttcccagt cagcaatagt
    17941 ttgggtaatt tcatccctaa cttcactttc actagccacc tgaatattgc tgtctgcatt
    18001 ggccgaatca ctgaggagag ccaggacgcc gtcacgacca atctctgcca aacgagcaaa
    18061 atcagttgca taagattcac tagccgtttg gtcaaatttg aagtcacctg tataaacgat
    18121 gcttccttcc gatgtcttca agacaattcc cagactctct ggaacggagt aagtcgtagg
    18181 gaagaaggaa accactgtcc caccaaaatc aatctccgta ttctcatcaa tgacatggaa
    18241 atcattaaat ttcttaacgg catcatttcc tttgacaaag agctttgcca actcaatggt
    18301 caactcagac ccaaatacag gaactttagc ctctgccaag agataaggta gagcaccaat
    18361 ggcatccgca tgcccgtggg tcaagaaaac cccagcaata cggtcgctat tttcaaaaag
    18421 gtaatccatg tttggaatca ccacatcgac ccctaattgt tcattttcag gatattttaa
    18481 ccctacattc aaaacaaaaa tggactctcc aatttcagca atgtacatat tttttccatt
    18541 ctcacgcaca ccaccaagtg ttgttaaact gatattactc atttttcctc caaaatctta
    18601 gtttatcttg attatagggc aattctaccc tcttattcta aaagttctga tactttcagc
    18661 cgaatctttt cctaccatta taccattttt ttgatgattt tcaaaatgaa ggtctgtttt
    18721 caaaaaagag ttgatttccc aactctttcc taacttctac tctttttcca tcaaaaaatc
    18781 ataaatttct tgcaccgtac ccagcgccat catttcttgg tctttaacgg tttgtttgag
    18841 attttggtaa atttgacttt ctcctatctc ccgctttggc gcctctttat tgactgtcat
    18901 cacaccatct tttatcgtca caaagcctag ttcttcaaat acttgaatca tcttgaccag
    18961 caagatttgt tgaatattaa gatatgcagc caaatctttc agcttgtagc gaatatcaaa
    19021 ctctgggaac tggtaaatag tcttgtacaa tttagcaaac tgatctctag tcccataacc
    19081 tgtcagataa taggtcttgt caatatcatt tttgaaatag acagcagaga aatgctgttc
    19141 ctgaaaaatg gtcttcagct gagtaatatc ctctggaatg ttttttacga caacagcttc
    19201 actagccgca agatttggca gttctccagg aaaatccaag actggaacac cttctggcaa
    19261 gactgcattt tttccacgaa tgttaaaaag ttgaacacct tccactcgcg catccaccat
    19321 catcaactgg agggcagttt ggccattcca ttggttgaca gacaatttaa ccgctaactc
    19381 tagattcttg gtttgagaaa actctgtcgc ccatctgcct tgaccaaagg ctaccacttc
    19441 aaaactcgcc tcacccttgg aaattttcag ctttagatgg gcattacctg cccccatagt
    19501 acgagcactt tcgacctgaa aattcttgat ataaaaaata ggtttctgat tatccattcc
    19561 aaaaggagct aaacgttcaa aacttttgac cgtttccaag ctaagtgcct ccaaatccaa
    19621 ctcttcatct aggtttaact tattcttgcc accagcatct gcaccttttt cacgaacata
    19681 atcttccaaa acctgagata aatctgagag ttgctcaact tccagcgtca tacccgctgc
    19741 acctgcatga cctccaaagg cgatgaagag gtctcgatgg ggatccagag cttcaaaaat
    19801 atcgaccgct tccacactac gagcactgcc cttggcacga ccgtcttcta tattaagaac
    19861 aatgactgtc tgtcccaatt cttccaataa acgaccagcc acgattccta gaaccccagg
    19921 attccagcct tccttggcca agacctgaac cttcttctca ggatccacca tggtcttggc
    19981 ttcttcatag atagactgaa cgatttcctt gcgctcttcg tttttctggt gaatcataag
    20041 ggcaatctca tgcgcttcct catcatcaaa tccagtcaac aaatcaatgg caggattggg
    20101 atcatccaag cggcccaagg cattcaaacg aggagcaatc tggaaaccaa ccgtttcttc
    20161 tgttacttcg ttggcagcaa tcccagccat gtccagcatt tcttgcagac caatgcgctg
    20221 ggtatgaccc aacatttcca gaccatattg aactaagata cgattttcat ccgtcagact
    20281 caccatatct gcaatagttc caatagcgac caaatcaagc aattccactt gcacttcttc
    20341 taacagggca caagccaact tgaaagcaac tccacaacca gccaaatatt taaaaggata
    20401 atccgcatct ggatgttcag gatggacaat agcataagca tctggcaggg tttcaggcat
    20461 ggaatgatgg tctgtcacaa tgacatctac tcccatagac tgagccaatg caatagcctc
    20521 atgaccagca accccattgt ccaccgtcac aatcaaggaa attccttctt gctcgataaa
    20581 gtatttataa acactagcat tagggccata gccatcggta aaacgatttg gcaggtaaac
    20641 tcggcactca gcaccaagtt gttccaaact ttccttcaca atagaagccg aagtcatgcc
    20701 atccgcatca tagtctccat aaacgagaat attttcccct tcttcaatag cctgacgaat
    20761 ccgctccact gccttgtcca tatcatggag cagataagca tcatgtaagt cctccaagga
    20821 aggttctaaa aacttcttca gactttcttg gtcctgaatc cctctctcaa acaataaccg
    20881 agccacctca ggacccagtc cagccttctt ggctatcttt gtaaaatccg catcttctac
    20941 ctgcagggca aactgccatt cataagtagg tgttatcaaa aagacatcca ctctttctaa
    21001 gaattctatt gcttcattat aacatgattt agacgttttc tctatccaga ttgctttttt
    21061 ataacatttt atagtatatt gaaactagaa tagtacacct ctacttctaa aatattgtta
    21121 gaaatcgatt tgactgtccc gatcgatttg tcctgttctt atttcactat agtgaatttt
    21181 ttcagatatg gtttgacaag aacattcttt cattgtagaa tcgtgttata aaatataaca
    21241 caaaggagat ctctcatggc tttagtagaa tttaaaaacg tcgaaaaata ttacggagac
    21301 taccacgcac tccgcaacat caatctccgt tttgaaaaag gacaagttgt tgtcctgctt
    21361 ggaccttctg gctctgggaa gtccactctt atccgtacga tcaatggttt agaggctgtt
    21421 gacaaaggaa gtctcctagt caatgggcac caagttgctg gtgccagcca gaaagatttg
    21481 gtacctcttc gcaaggaagt cggcatggtt tttcaacatt ttaaccttta tccacacaaa
    21541 acggtgttag aaaacgtgac acttgcgccc attaaagttc taggaattga taaaaaagaa
    21601 gctgaaaaaa ccgcccaaaa atatctggaa tttgtaaata tgtgagacaa gaaagattcc
    21661 tatcccgcca tgctatctgg tggacaaaaa cagcggatcg ccatcgctcg tggtcttgct
    21721 atgcatccgg aactcctcct ctttgatgaa ccaacatctg ctcttgatcc tgagactatc
    21781 ggagatgttc tagcagttat gcagaaactg gcgcatgatg ggatgaacat gatcatcgtt
    21841 acccacgaaa tgggctttgc tcgagaggtt gcggaccgca ttatctttat ggccgacgga
    21901 gaagttttag tagatacgac agatgtcgat aacttttttg acaatccaag cgaacctcgt
    21961 gcccaacaat tcctcagcaa aattatcaac cacgaaagtg acaaagtcaa ataaggaggc
    22021 gcctatgaaa aaaaattctt tttatcagca ttattgatta gccttttcgg ccttgctgct
    22081 gccaaaccag tccaggctga tactagtatc gcagacattc aaaaaagagg cgaactggtt
    22141 gtcggtgtca aacaagacgt tcccaatttt ggttacaaag atcccaagac cggtacttat
    22201 tctggtatcg aaaccgactt ggccaagatg gtagctgatg aactcaaggt caagattcgc
    22261 tatgtgccgg ttacagcaca aacccgcggc ccccttctag acaatgaaca ggtcgatatg
    22321 gatatcgcga cctttaccat cacggacgaa cgcaaaaaac tctacaactt taccagtccc
    22381 tactacacag acgcttctgg atttttggtc aataaatctg ccaaaatcaa aaagattgag
    22441 gacctaaacg gcaaaaccat cggagtcgcc caaggttcta tcacccaacg cctaattact
    22501 gaactgggta aaaagaaagg tctgaagttt aaattcgtcg aacttggttc ctacccagaa
    22561 ttgattactt cccttcacgc tcatcgtatc gatgcctttt ccgttgaccg ctctattctg
    22621 tctggctaca ctagtaaacg cacagaacta ctagatgata gtttcaagcc atctgactac
    22681 ggtattgtta ccaagaaatc aaatacagag ctcaacgact atcttgataa cttggttact
    22741 aaatggagca aggatggtag tttgcagaaa ctttatgacc gttacaagct caaaccatct
    22801 agccatactg cagattaagg aggacacccc atgatagatt tatcatcttg gacagcctat
    22861 tttcaggatt ttggacaatt tttcaatggt ttcctcttta ctcttgccct agcgattgga
    22921 tcctttatcc tcgccatggt cttaggaatc ttctttggtg ccatgtcaac cagtaaacgt
    22981 ccaattttac gcattttagc tcacatcttt gtggaatttt accaaaacac tcccctcttg
    23041 gtgcagtttg ttattgtttt ttatggccta cctcttatca gtgaccatac tatcatgatt
    23101 ccaatttatt ggacagctgt tctctgcatg ggactctatc acggcgctta tatcgctgag
    23161 gttattcgtt cagggattca gtctattcct agtggtcaga tggaggccgc cttgtcgcaa
    23221 ggttttacct atatcagtgc catgcgcttg attatcttgc ctcagacctt ccgcatcatt
    23281 ctccctccat tgaccaacca aattgttaac ctcatcaaga acacctctac tgtagctatc
    23341 atctctggag tagacttgat gtttgtgact aagtcttggt cggctctcaa cggaaactat
    23401 atcccagcct ttttaggtgc tgctcttctc tactttgctc tatgcttccc tgttgcccag
    23461 tttggtcgca agatggagca agccaacaaa aaagcctatt cactttagga ggttactatg
    23521 gaatctattt tagaagtttt aaccccagat aacctagtct ttatctttaa aggatttggc
    23581 ttgaccctct atatttctct gattgccatc atcctctcta ctatcatcgg tacggtgcta
    23641 gctgtcatga gaaatggcaa aaatcctgtc ttacgcatta tttccagtat ttatatcgag
    23701 tttgtgcgca acgttcccaa ccttctctgg atttttacta tctttttggt gttcaaaatg
    23761 aaatccacac cagcaggtat tacagccttt actctcttta catcagcagc cttggctgag
    23821 attattcgag gcggtctcaa taccgtagac aagggacagt acgaagcagg aatgtcacaa
    23881 ggcttcacct cagcccaaat cctctactac atcattctcc cacaagccat ccgcaaaatg
    23941 ctaccagcca tcatttctca gtttgttacc gtgattaagg ataccagtct cctctactct
    24001 gttatcgccc tacaagaact ctttggagcc agccaaattc tcatgggccg ttatttcgaa
    24061 ccagagcagg tcttcagtct ttgcatcctg attgccctca tctacttcag ctttaaccta
    24121 gcaatttcta gcctgtctca tatgctagcc aaacgttggc aacaagctgc agaataatac
    24181 tcttcgaaaa tctcttcaaa ccacgtcagc ttcaccttgc cgtatatatg ttactgactt
    24241 cgtcagttct atccacaacc tcaaaacggt gttttgagca gcctgcggct agcttcctag
    24301 tttgctcttt gattttcatt aagtataaac agccactctc cagttcaatt ggagagtttt
    24361 ttgatgagag tagatattta tagacctcaa tttgacacca tacattttct atgataaaat
    24421 gtaacaaatt catttacaac aaatcgaaat ctaaatgaaa tggaattttc tatgaaatca
    24481 gtcaaaggac tactctttat catagctagt tttatcttga ctcttttgac ttggatgaac
    24541 acttctcccc aattcatgat tccaggacta gctttaacaa gcctatctct gacttttatc
    24601 ctagccactc gtctcccact actagaaagc tggtttcacg gtttggagaa ggtctacacc
    24661 gtccacaaat tcacagcctt tctctccatc atcctactaa tctttcataa ctttagtatg
    24721 ggcggtttgt ggggctctcg cttagctgct cagtttggta atcttgccat ctatatcttt
    24781 gccagcatca tccttgtcgc ctatttaggc aaatacatcc aatacgaagc ttggcgatgg
    24841 attcaccgcc tggtttacct agcctatatt ttaggactct ttcacatcta catgataatg
    24901 ggcaatcgtc tccttacatt taatcttcta agttttcttg ttggtagcta tgccctttta
    24961 ggcttactag ctggttttta tatcattttt ctatatcaaa agatttcctt cccctatcta
    25021 ggaaaaatta cccatctcaa acgcttaaat cacgatacta gagaaattca aatccatctt
    25081 agcagacctt tcaactatca atcaggacaa tttgcctttc taaagatttt ccaagaaggc
    25141 tttgaaagtg ctccgcatcc cttttctatc tcaggaggtc atggtcaaac tctttacttt
    25201 actgttaaaa attcaggcga ccataccaat aatatctatg ataatcttca agccggcagc
    25261 aaagtaaccc tagacagagc ttacggacac atgatcatag aagaaggacg agaaaatcag
    25321 gtttggattg ctggaggtat tgggatcacc cccttcatct cttacatccg tgaacatcct
    25381 attttagata aacaggttca cttctactat agcttccgtg gagatgaaaa tgcagtctac
    25441 ctagatttac tccgtaacta tgctcagaaa aatcctaatt ttgaactcca tctaatcgac
    25501 agtacgaaag acggctatct taattttgaa caaaaagaag tgcccgaaca tgcaaccgtc
    25561 tatatgtgtg gtcctatttc tatgatgaag gcacttgcca aacagattaa gaaacaaaat
    25621 ccaaaaacag agcttattta cgaaggattc aagttcaaat aagtaatcat actctcctgg
    25681 gatttcccag gagagttttt tatagccaaa tgaaataaaa ccggaacgat ggaattttgg
    25741 cattcaaatc aattgataag aatattttat agtggagtga aataggatac gaacaaattg
    25801 attaggaaaa tcaaatgaat ttatagaaat cttttagcag ttatgttgtc ctattctagt
    25861 ttcaaaacgc tatagaagca gcattgtgct agtctagatt cagtttacta tactaaaacg
    25921 agtagcttga aatcaaaaaa cccaccctca caggcaggtt ttatctgtat tattcagcta
    25981 gattatgctt taccttctga accgaatacg tcgatacgtt cttcaaccga tgcttggata
    26041 gcttttacac cgtcagccaa gaatttacgt gggtcgaaga gttttttctt gtcgtattct
    26101 gcttcgtttg cttcgtagtc acgagcaaat ttacgagttg cgttagcgaa tgcgatttgg
    26161 cattctgtgt taacgttaac tttggcaaca ccaagtttga tagctgcttg gatttgctca
    26221 tcaggaatac ctgatccacc gtgcaatacg attgggaatc ctggaagagc ttctgtcaat
    26281 ttttgcaagt ggtcaaggtc aagaccttcc cagtttactg ggtaagggcc gtggatgtta
    26341 ccgataccag ctgccaagaa gtcgatacca gtttcaacca ttgctttagc gtcttcgatt
    26401 ggagccaatt cacctttacc gatgattccg tcttcttcac caccgatagt accaacttca
    26461 gcttctactg agataccttt agcgtgtgct ttttcaacaa cttctttagc caatttaagg
    26521 ttttcttcaa ctggaaggtg tgaaccgtca aacatgattg aagtataacc aacttcgata
    26581 cactcaagtg catcttcgta gtgaccgtgg tcaaggtgga tagctactgg tacagtgata
    26641 cccattgatt caacaaggtt agcgatcaag ttgcgagcaa ctttgtaacc acccatgtat
    26701 ttagcagcac ccattgaagt ttggatcaaa actggagctt ttttagcttc tgctgcgcgc
    26761 aagatagctt gagtccactc aaggttgttt gtgttaaatc caccaactgc ataaccgttg
    26821 tcacgggctg cttggacaaa tttttctgct gaaacgattg ccattttatc aggcctcctg
    26881 tatattttta tgggtcatcc catttacatt gttcatttta tcactttttg ccaaaaaaat
    26941 ctagtttttc ccgcagtttc gattgatttt cttctaactc catctatgta aaccctttct
    27001 ctccctagtc ttggacgact tttggaaaat ctataaagaa ggttaaacga ttctcctcca
    27061 tctcgaaacg ataagctaat ttttcatgtt ctaatagact cttaaccaca aagagcccca
    27121 taccagaccc cttgaccttg cgactggcat tgtcagaaaa agactgggct agtttttctt
    27181 gttcctctga gctacagcta ttttcgataa aaagttctcc ttctctttct ccaattcgaa
    27241 ctaagccacc tggaacagag tgcttaatgg cattgctgat gagattagaa agaatcaact
    27301 tcataactga tgggtttaga taagcctgct gatgggtcaa actattgtct atctggagct
    27361 ctctttcctt ggctagcaag gcataatctt tgaccagatt ttgcgtcatc tggaggaggt
    27421 caattgtttc cctatcatct cgcaattcct gcacagaaga gagggaaagt atctgcagaa
    27481 catggtgatt gagttcatcc acaatcccca aggcaactcc cagatactgg tctctatcct
    27541 tataacgacc gatattctct ctcatatttt cgattaggat tttcaaacta gccagcggtg
    27601 ttttcaattc atgagaagct cctcgtagga attcgacctt catcttctcc agctggagaa
    27661 tggcttcatt cttttcatgc aagtccgcaa taacagtcaa gagatgctgg tagaggctat
    27721 tgatttgttc cttgagatta cctatctcat ccttagaatc cacgcgcaat cgcacttggg
    27781 aatccaggtc catcatccga cgggtcaccc gcttgatttc caagatcggt gcaacaatag
    27841 tccgagcgta gatgtaggcc accaagaggg aaatcagaaa ggaggccagc aaggtatagg
    27901 gaagaaactg gagactgatt tgctccgctt ccttttgtaa atccatggaa gctagaaact
    27961 ggagaatcat agtagcaccg tcttgcgttt tcacctcgcg ctcctcaata aagagagagg
    28021 ttgtctggcg gtctgtgtcc agaggaagac tgtccttgac ttctaacttg tcctcggtca
    28081 tctcaccttt gacggtcccc ttgatatcac tagtctggga atacaagtct aacacttgct
    28141 cgatactctg cctatctttc ccttctaggg actgggcaat ggctgttgcc ttttgaccaa
    28201 tggtttcctg acgatgactc agataagtcg aaggaaaaag aaaataaata gctaaatgaa
    28261 ggcagataac cagaacacta aatatcgaga aggtatagat aaatatcttt gcaaataaac
    28321 ctgttcgttt cattttcgct ccaatttata accaacattg cgcacagtga ggatacaatc
    28381 caagtctagc tttttccgca attccttgat ataaacatca ataacacggt caaagggaac
    28441 ctcatctgtc gctttccaga cggcatcgat aatctgagat cgagtcaagg cccggccttc
    28501 atttttcact agatagtcca gaatttccaa ctctttggca ttgataggca cttcttgacc
    28561 tgcgatgctt gcactgtagc tttcaaagtc caccttggta tccttgtaag aaaagattcg
    28621 tcctgtatcg tagtagcgct tgaaaatcgc gtccaccctc acttttaaaa gggagaggga
    28681 gaaaggtttt tccagatagc catctgccaa agaggcaaag gcactcatct tgtattcctc
    28741 atcttgaaaa gctgtcaaca tcaagacagg aacctgactg gttttacgaa tctcagctag
    28801 gacttctaag ccgttgagct tgggcatctg gatatccagt aaaaccaggg ccacctcata
    28861 gctagaaaat tgctccagag cttcctgacc gtccgctgcc tcaatagttt catagccaca
    28921 atccgtcaaa taatcactga ccccctcacg gatcatctct tcatcttcta caattaaaat
    28981 tttcatactt taactgctct ctatttttta tttttcttag aataaatacc tactctattt
    29041 tctattatag tctcttgctg gccttttgtc tgcaagcaac tgaccactag ataaaacgtt
    29101 gtgaaattcc tttctcataa attccataac tttagtatat tatatttaag cactaaagta
    29161 caaagaaagc aactgaaagc aatgattttc accactgctt tcggatttat tttgaattgt
    29221 taaatagcca ttcctatcca ctattcttga atagaaacac aagatgcaat ctttattcta
    29281 gactcatttt ttcaaattta ttcaccatcc agcaagagct cttttggttg ttttctaagg
    29341 agattgcttg aagcaagcgc cataacgaga accactagaa ccaaggcaag gacaaaaatg
    29401 atgataaagt ctgatgtctg aatggaaatg tctaggctcg acaaggtctt gctaaagcca
    29461 tctacttctg caccaccacc aaggttagag gcttgagccg ccttactagc ctgtttggca
    29521 acacctgaag tcacattggc aaggacagtg tttccaattg cacgggcagt gtaattagct
    29581 aggaagtaag cagaaactag agcagggata gcaatcaaga tagattcggt gatgaattga
    29641 cccaagatac ttgcctgctt gaggccgata gagaggagaa ttcccacttc cttgcgacgg
    29701 gcgttgatcc aaaggctgag caagagggca aggaggagaa ctgagaagct caagctaccc
    29761 cagaagagga ggttggccat cttgtacata ccagagatag attgctcaag agctgggtag
    29821 ttagaggagc tcttgacgag tgtgtagctc ttccagttga taccactgat gccattcaac
    29881 tctttcataa catcatccaa gttcttgtct gctgttacaa agaaggttgc gtccccataa
    29941 atggctgtgt cttctgtgta tccataaagt tttgcagcag tgtgaatgtc tgtaatagct
    30001 gtgttttcgt aaagttcttg tgagtaggtt actgctgact tattatgacc atcaaagagt
    30061 cccttgattg tcacttcaac tgtttccttg gctccttttt cattatctgc atcgtagata
    30121 ttagagtcca gtttaacctt gtcccctact ttccagccgt gtttggctgc caagtccttg
    30181 tgcaagagga ttttatcctt gtcgtcgttg gttaagtgct ctccttcgac tagtttataa
    30241 gaaccagaga caaacttgtc ttctttagag gagtcattga cacctgtaat catcaagcta
    30301 cttccaaaac gcttggcacg atcagcagtg agattcttct tggtttctgg cgtttcaatc
    30361 aggtcatatc cagtcaaatc tccgatagcg ttgatacgtt tgacataaga ctcgatggcc
    30421 ttgttttcgg tgattttttt gatgtcttca cccttgatat tcccagcacc acgaggcgtt
    30481 ccttggttga cgcgacgatt gatttgcatg gagaagctat tagtgatatt tttaaaggtc
    30541 tcctgagaag ccttggcagt agctcccttg attgacaagc cgaccaaact caagctcgcc
    30601 atgaggagaa taatcaggaa gatgacaatc gatttgaaaa acttccttgt aacataggca
    30661 aatgcgttgt gtaacataga ttccctttct agattttgtt ttaatcattc tatcaaaata
    30721 agctcaaatt atttactagt attgcgcgtt tcagtcagtt tcttatcctt taattcaagt
    30781 gtaatatctg acgcttgtgc cacttcttta ctgtgagtta cgacaatcac acatttacct
    30841 gttttctggg caagtgattt gagtagttcg acaatatctc cagcagtttt aggatccaga
    30901 tttcctgttg gctcatcagc tagaataact ggagcttctg agaccaaact gcgagcaatg
    30961 gcaacacgtt gctgttgacc acctgataac tggagaacat tccgcttgat ctggctttca
    31021 tccaaaccaa gctcaagaag tgtatccttg cttgcctttt tgttgaccaa gcggatattt
    31081 tccagcggag aaagataatc tatcaagtta taattttgaa agaccaggga aatatggtgc
    31141 atgcgatggt aagaatagcc cttcttacga atatcctctc cttgaaaaag gatagaacct
    31201 tcaacaggac tatctagacc agcaagtagg gacaagagtg tggattttcc tgctcctgac
    31261 tccccaataa tactgtaaaa ttttccaggt tcaaaattat aatcgatctg atataggact
    31321 gcttcagcag tattcttata acggtaggta acatcttgta attgtaataa agtcatgatt
    31381 tctccttctt aactaataga tgataaaatt tctttcggtg attttctaaa taagaatagg
    31441 aaacaaaggg ctacagataa gcaactaagc agaactagaa aaacatagga ttctgcaaaa
    31501 gataagatgc tagttgataa actgcttgct ttggctagtg tatcttgtaa gcttgcctga
    31561 tctccacttg ctagtagagt ttggagtaga taacttgtga ttccgtttcc tgcaacaaat
    31621 gctggaagca aagctccaag agataccaaa actacctcta aacagaattg taggaagatc
    31681 gagctcttgc cttttccaag tgcaagtaaa atccccactt catagacccg ttctctcaac
    31741 cagagagaca aaaccagaat taaggctcca gctcctgcta tcaacatccc ataaaggaag
    31801 atggtcaaga aggtttggaa agttgcaact gagtctttga tttgttcaaa agccttgttt
    31861 tccttttcga cttggtagcc ttgattttcc aaggccaagt tttctacctg cttcatgagt
    31921 ccgtccattt ccttaggatt ttctacatag aagcgtgctg cactgacttg agcttcacta
    31981 ttgcccaaaa gggtttggct actttcatag tctgtaaaga cttgattttc actgaagtca
    32041 gaagacaagc ctgtgaattt ctcttgtttt ttaccagaaa agatgccgat aatctcaaac
    32101 tctactgttt gtccttttcc agattcagac tgaccagcat ccaagccaat cttgtcatga
    32161 agtgaaagac cgttcttctt agccaattct tcgtggataa ggattttctt ggaatcccct
    32221 ttttgaaggt gtcgcccttc ttttagattg aaagccgaac tggtaaaggt tacatccttg
    32281 gatgaatcct caagagccgt taagctaacc aagttattgt ctgcagctga taaatcatca
    32341 cgctccacgc tctgctcacc agtcactgct tccttgtctt ttagttttgc gaccgtctca
    32401 agttcaggag agacattttc cagcccctta atcttgctta cagatgctag gtctgacaac
    32461 ttgaatgtct gaccattctc tatcttctta atagaaaaag atgtattgag tgatttataa
    32521 agattgcttt ctactgtttt gttggacttc atcagagtca aacaggctga aattccggcc
    32581 aataagacca ataaaatcag aaataaaata aaacttctca gtcgctttct gctgacataa
    32641 gcccaagatc tttggattgg attcatttgt cacctccata tttgtaagac tattataaaa
    32701 cccaaatatg aaatgtttat gaaatacgaa aaaaaatatc gagtagggga taatctctag
    32761 cccctctcac accaccgtac gtgccgttcg gcatacggcg gttcaactaa cttttaacgc
    32821 atgtcgttca aggtaataat ccaaacacga aacctgttca cgtttttcaa ggactggttt
    32881 tgatatagca cgtttaagta ccgacttctg agctactata gtagattgaa actagaatag
    32941 tacatctctt cttc
//
LOCUS       DAVBEM010000022        31002 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVBEM010000022 DAVBEM010000000
VERSION     DAVBEM010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31002
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.022"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(298..516)
                     /locus_tag="VQ548_001031"
     CDS             complement(298..516)
                     /locus_tag="VQ548_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2653896.1"
                     /translation="MVLNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(762..1040)
                     /locus_tag="VQ548_001032"
     CDS             complement(762..1040)
                     /locus_tag="VQ548_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653897.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEMLELACWFRVIIVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYSIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(1254..2885)
                     /gene="rlmD"
                     /locus_tag="VQ548_001033"
     CDS             complement(1254..2885)
                     /gene="rlmD"
                     /locus_tag="VQ548_001033"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET2653898.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSLHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWCTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2959..3933)
                     /locus_tag="VQ548_001034"
     CDS             complement(2959..3933)
                     /locus_tag="VQ548_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HET2653899.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(4007..4621)
                     /gene="pmp23"
                     /locus_tag="VQ548_001035"
     CDS             complement(4007..4621)
                     /gene="pmp23"
                     /locus_tag="VQ548_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HET2653900.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(4621..5595)
                     /locus_tag="VQ548_001036"
     CDS             complement(4621..5595)
                     /locus_tag="VQ548_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HET2653901.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQKENGTYSILIKNIEDIQSK"
     gene            complement(5603..6859)
                     /locus_tag="VQ548_001037"
     CDS             complement(5603..6859)
                     /locus_tag="VQ548_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HET2653902.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(6921..7352)
                     /locus_tag="VQ548_001038"
     CDS             complement(6921..7352)
                     /locus_tag="VQ548_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2653903.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(7354..7956)
                     /locus_tag="VQ548_001039"
     CDS             complement(7354..7956)
                     /locus_tag="VQ548_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HET2653904.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7940..8779)
                     /gene="prmC"
                     /locus_tag="VQ548_001040"
     CDS             complement(7940..8779)
                     /gene="prmC"
                     /locus_tag="VQ548_001040"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HET2653905.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(8779..9858)
                     /gene="prfA"
                     /locus_tag="VQ548_001041"
     CDS             complement(8779..9858)
                     /gene="prfA"
                     /locus_tag="VQ548_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HET2653906.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9855..10445)
                     /locus_tag="VQ548_001042"
     CDS             complement(9855..10445)
                     /locus_tag="VQ548_001042"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HET2653907.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRGLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            10568..10750
                     /locus_tag="VQ548_001043"
     CDS             10568..10750
                     /locus_tag="VQ548_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HET2653908.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10887..12260
                     /gene="mnmE"
                     /locus_tag="VQ548_001044"
     CDS             10887..12260
                     /gene="mnmE"
                     /locus_tag="VQ548_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HET2653909.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEANLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLIEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(12307..13242)
                     /gene="dapA"
                     /locus_tag="VQ548_001045"
     CDS             complement(12307..13242)
                     /gene="dapA"
                     /locus_tag="VQ548_001045"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HET2653910.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(13298..14374)
                     /locus_tag="VQ548_001046"
     CDS             complement(13298..14374)
                     /locus_tag="VQ548_001046"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HET2653911.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(14716..14788)
                     /locus_tag="VQ548_001047"
     tRNA            complement(14716..14788)
                     /locus_tag="VQ548_001047"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14753..14755),aa:Thr,seq:ggt)
     gene            complement(14888..15397)
                     /locus_tag="VQ548_001048"
     CDS             complement(14888..15397)
                     /locus_tag="VQ548_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HET2653912.1"
                     /translation="MKKLTIRDIADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(15395..15491)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            15520..15951
                     /locus_tag="VQ548_001049"
     CDS             15520..15951
                     /locus_tag="VQ548_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HET2653913.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKAYIFRK"
     gene            16033..16410
                     /gene="mscL"
                     /locus_tag="VQ548_001050"
     CDS             16033..16410
                     /gene="mscL"
                     /locus_tag="VQ548_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HET2653914.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(16452..17546)
                     /gene="hemH"
                     /locus_tag="VQ548_001051"
     CDS             complement(16452..17546)
                     /gene="hemH"
                     /locus_tag="VQ548_001051"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HET2653915.1"
                     /translation="MKKAILMMTFGSPEEISFEGVAEFFTNIRRGVRPQDHEIQTLYD
                     NYIRIGGTPLQRITREEVNLVKERLGEEYGIYFANKFSRPFIPDVIKQMETDGVEECI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEVLLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            complement(17624..18456)
                     /gene="srtG2"
                     /locus_tag="VQ548_001052"
                     /pseudo
     CDS             complement(17624..18456)
                     /gene="srtG2"
                     /locus_tag="VQ548_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218039.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG2"
     gene            complement(18534..19532)
                     /gene="srtG1"
                     /locus_tag="VQ548_001053"
     CDS             complement(18534..19532)
                     /gene="srtG1"
                     /locus_tag="VQ548_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000851047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG1"
                     /protein_id="HET2653916.1"
                     /translation="MKTKREKPKKSLSRRLVLAVDGVINHLLLIFAALIFLFGFYALW
                     DSNQVYSLASSSEYEAYRPVTTQQDELASFSGFSKLQELNPEVLGWINVYGTNIDYPL
                     VQAKDNEKYLNKDSKGEFAATGAIFLDARNNPKFEDFNTIIYGHHVENGVMFGDVAKF
                     ADQEFFDQHRYGSIYYNGVEKGLEIFEMLEVDAYDFNIYDPGIQGEDRQQAYLDHLLS
                     VAMHKRDISLSPSDRIILLSTCFLDVTNGRHIVVAKITDTVPKNTFHTKKSKPFPYSV
                     FDDSSLGRFLSSIPLWIWYLILFVLFLLLIFLLLVLYLILRRRRESKKNARSRPFY"
     gene            complement(19550..20746)
                     /gene="pitB"
                     /locus_tag="VQ548_001054"
     CDS             complement(19550..20746)
                     /gene="pitB"
                     /locus_tag="VQ548_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus major pilin PitB"
                     /protein_id="HET2653917.1"
                     /translation="MKKTFFKKLFTASIAAITALSVFRGVPTFADDNSAITKANGENN
                     AVVKINKTLNIAEGITTPTATFTFKFTEKTGQSSNGAPYQTGVAIPDRNVEYNKNDHP
                     TADKIQKATEDIFSGVAYGHAGEYVYDVAEAKTGWQAITKNGKTIDAMRYDKRTYEMH
                     VIVKNKVNGGVYISSVYFKENNKSNAPKVEPSEQGVYNLFDNTYTKDASKEPNPDDPS
                     QVDPNAKALTITKKVDGASGDKTRDFQFHIKIQLPSTNKTAETPVTNIIVKHGSKSEV
                     LAVVTPADTVEYNFTLKDGETFTVEQLPAGSKYTVTETGVAGYTDSSIYTTNGAEQTS
                     QGQKNVDFTLTDILIGEKKNDNKVTNKIDDVTPTGLLIDNLPFILMIGLGLAGFVVLS
                     KKRREA"
     gene            complement(20791..21342)
                     /gene="sipA"
                     /locus_tag="VQ548_001055"
     CDS             complement(20791..21342)
                     /gene="sipA"
                     /locus_tag="VQ548_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system signal peptidase SipA"
                     /protein_id="HET2653918.1"
                     /translation="MLLKKKHKKPVTQVNRDKSPPSVWGDILYLVSKLLMVGFVLAIL
                     YFFVFGLLRYNDDGMKPALKDGDLVVYYRLDKRYSIGDLLVYSYKGKERVARVIATEG
                     STIDINENGLIINGSPQQEQDIYKETLLYKEGATFPMKVPAGQLFVLGDNRTTAVDSR
                     AFGTIPIQDTQGKVVTVIRRRGF"
     gene            complement(21342..23105)
                     /locus_tag="VQ548_001056"
     CDS             complement(21342..23105)
                     /locus_tag="VQ548_001056"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653919.1"
                     /translation="MIDTPYWFTSGLERGMLNISSLIAPKIDGFYSIKFRYYIGSNDS
                     ITSLKGYISGYNSGIPNEIFSANNENDLQQKFKEITDKILPLGVHHVTISDVLSKYVQ
                     LLPGDASHLRVVKIKDGNEQELNDNQVTIETKKNEQGLVEVTAKFNPSYTLEDDAKYV
                     LKFTVTSSQEAFDAIAGDKTLTSDDAEEADATKLYSNKGAKVAYSYGIGTSRTKIKDY
                     SEKPTFKPSDPLTVPVEIEWKGVDGKSNPSANRPPSVELNLNQKKDGSIKDSYRKVTS
                     PVQTNSFTENTSFAKVAKGYDYELKAPDAPGYTVEVQKTGTKEKPSFKVIYRQLPSLT
                     VKKILEGEQSPNKSFTINVTFSDKDGKPINGKFGNTTVTNGKAQISLKNSQETALSYL
                     PRDTHYKVEEVENSRTGYHVTYEKQEGTLSEDVQTIVTNHRLPTLSVTKKVTGAFANL
                     LQSFKITINVKDAQNKPLNGSYSAIVNNQKTTLQFTNGKATVDLKKDKTIKILDLPLN
                     ARYSIEEEASSSRGYQVSYDKKEGTLDANKSATVTNNKNSVPETGIDFLSSTLVLGVV
                     LPLGGIFFIILLGHLVVNRRK"
     gene            complement(23427..23930)
                     /locus_tag="VQ548_001057"
     CDS             complement(23427..23930)
                     /locus_tag="VQ548_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HET2653920.1"
                     /translation="MNVQYDFKKIQYFTSSLVIFLAILFLCAPINSLRADSITEPQTT
                     LHKTITPISGQKDQYELSLDITSKLGTETQSEPLDVVLVADLSGSMEERDVWSYSSRR
                     YISRIEALKHTLKGVNGRQGLIDTILSNSQNRLSIVGFAGKIDNQYNDRYYNEYYLSY
                     QYGTWPN"
     gene            24289..25512
                     /gene="pepT"
                     /locus_tag="VQ548_001058"
     CDS             24289..25512
                     /gene="pepT"
                     /locus_tag="VQ548_001058"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HET2653921.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPRQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(25548..26177)
                     /locus_tag="VQ548_001059"
     CDS             complement(25548..26177)
                     /locus_tag="VQ548_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653922.1"
                     /translation="MNKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSANSKDKTALLESTKAILVLNHQIQSKVSASEETSPARNAEANSDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            26142..26363
                     /locus_tag="VQ548_001060"
     CDS             26142..26363
                     /locus_tag="VQ548_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653923.1"
                     /translation="MDLFQELICLVQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(26634..26982)
                     /locus_tag="VQ548_001061"
                     /pseudo
     CDS             complement(26634..26982)
                     /locus_tag="VQ548_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(27087..27647)
                     /locus_tag="VQ548_001062"
                     /pseudo
     CDS             complement(27087..27647)
                     /locus_tag="VQ548_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(27873..30992)
                     /gene="phtE"
                     /locus_tag="VQ548_001063"
     CDS             complement(27873..30992)
                     /gene="phtE"
                     /locus_tag="VQ548_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HET2653924.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQISQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         8835 a         6360 c         5686 g        10121 t
ORIGIN      
        1 aaaaggatct agtttttatt tttagttaaa ttatgtctat atttttcatt aactcatcaa
       61 taaaaatttg tttgctaata tctctttctt ctgattttgt ttcaaggatt attgctacat
      121 cattcatatt tttaggtaaa taccaaccat ctggcttatc tgaatatccc ttgaagccta
      181 attgattaaa agtagttatt tgaccagtac cttgattgat gttttcttca acttcattaa
      241 agcctatact tctcttgcat aatccctaac ttgatcttct gtccttaaag tcattttcta
      301 ttcctcgtca ctaaaattat cttcaaaact aataatatca ttaggagtgc aagataaagc
      361 cttacatatt ctttctaaat tcttaaatgt aattggttta tcctttccca tttgtgccat
      421 aacatttgtt gtaagtcctg ccatagctat tacatctgtt ttctttagtc ctttttttgc
      481 taactgtatc cataatggtt tatagttaag taccataata tccctctttt tttcttcatt
      541 aaatttattt aattatagca taaatattga tttcattcaa tcttacattg atttagtgat
      601 ttgttttaga gaatttgttg tgttattccg tccttatttt gccataaatt gttttaagtg
      661 ggacctctta tccttaccat ttttacctcc taattttgag tataaaaaag acgatagagt
      721 ttttaatttc tatcgtctga gatttacata ttaaattttc atcacaaaat aagactcttt
      781 aaagaatctt taaattcatt ggtatgctgc ttacaatatc cattattaaa atggatacta
      841 taagcagcac accaactatt tattttttga gttttaaact ttggtagaag tcttgaactc
      901 cttatattta cataactatt tgcctctata actattatga cacgaaacca acaagcaagt
      961 tcaagcatct ccatatcttt attcaaatga ggactaagat attcacaaac tttatcataa
     1021 acctctttat cttttttcat aaaaggggca tacaacttag caaatttatc ctaaaatttt
     1081 ttgttgcctt tatcaatcat ttcaacgctc ctttaaatat aaaaataatc ctatcaatct
     1141 ttatattgag cctattttct aattgatacc ttgcaagaaa ggaataatag ctgttcctat
     1201 accaagtagg aatgtaataa atgcagaaag tcatatactg tcattctttt ctattaaatc
     1261 attttgaagt gtctcaaagc atccatgatg gcttcttctt tttcaggtgt acactgtgga
     1321 ataatttgtt tatccttttt agacttgttg taatgttctc gtaattctat tccacatttc
     1381 ttttttatct gtgcaatata taatgtcgaa acttttaatt caaatttatt ccaaacatat
     1441 tctttgattt gagcatatgt tgctttgctc tccgcacttg tcaaatccat ctcatccagc
     1501 tcaatttcaa cacttatgtg cttatcgaca tcgagtttgg acaaaagtgc taccgtctcg
     1561 acgtgatgcg tttgaggaaa tagatccacc ggctggactt tcttcaattc atatcccaat
     1621 tcttggtaga gtttgatatc acgcgccatg gttgcgacat tgcaggagat ataggcgatg
     1681 cgatcggctc ctgtttgggc gcttgctttg ataaagcttt ctgtcaagcc cttgcgtgga
     1741 ggatcaacca agataacggt tggttgaata ccttccttga gccatttctt catggcattt
     1801 tcagccgtgt cacagacata gtgggcatta gtaatcttgt tcaaagaagc attcttctgg
     1861 ctattctcaa ccgcttctgg aatcagttca acaccgtaga cttctttgac atgcttggcg
     1921 actgataaac caatggttcc aataccagaa taagcatcaa taaccacgtc atcttttttt
     1981 aactctgcaa agtcaatggc tgtttgatag agtttctccg ccatttcagt attgacttgg
     2041 taaaaggctg ggccagcgat ttggaagtca tttcccaaca tctggtccgt aatatagtct
     2101 tgaccataaa gagtgcacca ctccttacca aaaatcgcat tggtattctg gtcgttgata
     2161 ttttgcatga cagacacaat ctctgggaac tgcttgataa cttgttcaat caattggtca
     2221 acacgaaaaa cttttggacg agttgtcacc aaaacgacca tgatttgtcc tgaatagtga
     2281 ccacgacgca ccacaagatt ccgaatcaat ccagactgtt ccttttcgtc ataaggtttt
     2341 aaatcaaaac gacggagcag gtctcgaaga gctactacga cttggtcaat gacaggatcc
     2401 tggataaaga aatcttcaag gggcatgagg ttgtgcgaat tcttacggaa aaatcctgtt
     2461 tccaagacac cattcactcg acgaacgggc acctgcgcct tattgcgata cttgactgga
     2521 tgttccatac caagcgtttc agcaacttct acatctgcaa ttccagcaat cttgtagaga
     2581 ctgtccttga cttgcttggt tttaaacttg agctgttctg gataagaaag gtgtcctaaa
     2641 tccgcgattc ctgaacgcag gtaagccaaa tctagatctt gattacggtg tagtgactgg
     2701 acaaggtatt tttcaacttt tccaaagcca atctttttat tgaccttgag gacacgcatg
     2761 agaatttttt cactcggtaa agcattctct acaaaaaaga ccaaaccatc taccttggca
     2821 actcctgccc cttcatgggt caaatcaaca atttcaactt ctacaatatc atttttcttt
     2881 aacattcttt tctctttcta ttggccgaca aaaaagacgg caacgttacg attaccatcc
     2941 attataccat gaaatttctt aagaaccaaa actcttgaag aagttgacaa gggcttgcca
     3001 gagggagctt aagaagttac caccgtcctc tagcgcctta tccgcatcaa agttaaggtt
     3061 gatattttta aaactgtcgc cagcttgtga tacgatgctt tgtttaaggt catttagggt
     3121 tttagtgaaa tctgcattgc tgaggatatc actctttgag agattcaagg caaaattgat
     3181 gatgatattg atctggtttc ctgttatgac ctgatcaagt ttgtaatttt ttaaggtatc
     3241 ttcaacaatc ttgcggacat cttcttctgt cagatttccc ttgctttctt tagctttggc
     3301 gagtcctgac ttgatatcag ctagggcaac gtttaattta ttagcatcat agcctgattt
     3361 gtccttgttt tcagcattga tatctgacaa agcctttagc tcttcttgag ccaaatcttt
     3421 attggcttgc ggcaccttgg ctccattagc ttctagcgaa tagtagatcc cagccaaagc
     3481 actctcacct gtaactggaa taggggctgc tacagtgatt ttggcatgtt ccatacccag
     3541 cgttactgct gcgtttcggt acatatcctg agtcacctta gtgatatttt ctggtgtttc
     3601 aatcttgacc tcaagtggcg atttgtcacc tagcttttga atcttggctg atgaatacaa
     3661 ctgtaagcta gagtcattgg ccacattcat gattttagaa taaacatcag gtgtcatggt
     3721 cttgagttct ttggtatctg ttgaggcatt gtagcccagt tttttaagag tttgattttt
     3781 ttggtcttca gatagggagg aacctaggac atattcaggt tggacatagg tttcatcgat
     3841 aaccttttga acatctgttg ctgcatggac gctattcata gctgttactg cccacaagac
     3901 cgcagcactg gtcagaaaga gtttctttct catagggaat ttcctccttt acttttctag
     3961 agtaatatat ctatcttaaa gaaaacttat aacaaaaaca cctggtctag ccagatgttg
     4021 aaaagagagt gaaacatttg atgatgtaaa ggttaagtcg tacctgtcta gaataataat
     4081 agtttcctcc atttacatag agttcagcac cgtgaaaaat ggaaatgggg tgaatataac
     4141 tataagtctt tccagtcgta ttaccaagca agggggcaac agtctcacga gagtactgtt
     4201 tggctagagc caaggtattt tccttgccat tttgggcgat aaaatcgata taggcaggtc
     4261 caaaattata ggcttgaaca gctgtccaga tatctacccc cttcttctgc gccagataga
     4321 gattgcctgt cagagtttga atgccttgcc gaatgctaga ggcattatca ttgatggtgt
     4381 tggttgaacc acttgcagac tcactagact gcataacatc gccttctttt ccttttgttt
     4441 cagtataaat catagcaagc acaagctctt cgtttgctgg ggtgtctttt tcactcaaga
     4501 tttctcgcac catgggttga taggtcatga cttgtttgac atcttgatga acgcggtaag
     4561 ctttatagcc agcaaaaagg aagactgcta gtacaagcac tcttcgaatt cgtttaaaca
     4621 ttatttactt tggatatcct cgatattttt gattaagata gagtaggttc cattttcctt
     4681 ttggataaac tcaacagact cggcgtcttg atagacgtta ttgggaacga tgagctcaat
     4741 tccatttgat aaggagagtt tttggttttc aaatttcttt aattggcgac tggcatcaat
     4801 ttcatcaaat tgaacaggtt ctggtacggc ttctttgact tggtcaataa agctcaaacg
     4861 agccgtcaga ttgttgtcaa aaaggtcatt agccaatttc tcaggtgaca attcattgct
     4921 ttcttctagg ttgttgaaaa tcgctgattt gaccttggat tgaaattgaa aatcatctgt
     4981 gttaaaagat tcagcaattc tctgggctgt tttttccagt tccttgatag attttttagg
     5041 agaaatctta ggagcgacag caagaagatt atctgaaaaa tagttcaaaa aagtcccgtt
     5101 gtacttgatt cgtttttcaa tcaggtgata cttgcgactc tgaagattga ccaccaaggc
     5161 ctcgtcagca cccgttccaa atccaggcag gttattctga gtcagcttga ttggattatc
     5221 aacttctcct ccgaggtggg tcaaggtctc ccgcagggca attcgcaaga aagcgaaatg
     5281 ttctacacct tctttagaaa attgaacaaa aatcaagtca ttggtcttga gattttcaga
     5341 aatgctaaac tcctctttcc agagattagc cagcgttact gatgtctcca acaaatcgtc
     5401 tgtaatatga ttgaagaagg gattttcttc ttcgaaaatc ccagtcttgg cttcatctga
     5461 atacacatgt tcaatttttt tacgtaggta ttcttcgatt tttggagtaa tattgagaaa
     5521 cttatctgct aagaacagct cggtatcatc cggactgaac tggtgaataa tggctttctt
     5581 aatataaatg tccataaaag ttttattcct cgtataatgg gaaggcatct gtcaattctt
     5641 tgactgcact tctcacttct tctaatacag cctcattttc tgaattctta agggttttaa
     5701 tgatgagttc agccactttg cgactttctt cttcaccaaa tccacgtgca gtaatagctg
     5761 ctgctccgat acgaatccca cttgtcttga atggtgacaa ggtttcgtaa gggattgaat
     5821 ttttatttag ggtaatattg acttcatcca gcaagttttg agcaactttt ccgttttcta
     5881 caaccttagt cacatcaaca aggaagagat ggttttcagt tccacctgaa ataatacgga
     5941 aatcagggtc ttgcaagaag acatctgcca tagccttgct gttcttaatt acattggcag
     6001 catattcctt gaaggctgga tccaaaactt ctttgaagga aactgcctta gccgccacaa
     6061 catgctctaa aggaccgccc tgaatacctg ggaaaatagc tgaattgatt tttttagcaa
     6121 gttcttcgtc attggtcaaa atcaaaccac cacgaggtcc acgaagggtt ttgtgggtcg
     6181 ttgttgtagt gatatgagcg tatggcactg ggcttgggtg aagaccagct gcaaccaagc
     6241 cagcgatgtg ggccatatca accataagct tcgcaccgac agcatctgcg atttcacgga
     6301 attttgaaaa gtcaataatt tgagaatagg ctgaagcacc agctacaatc agttttggtt
     6361 ttacttcttg ggcttgtttc aagatagcat caaagtctaa gagttccgtt tcaggatcaa
     6421 cactataaga aacaaagttg taggtttgac cagagaagct aacaggagcc ccatgagtca
     6481 aatgaccacc tgatgccaaa tccattccca taaccgtatc acctggctca atcaaggaca
     6541 tgtaagccgc acagttggcc tgacttcctg agtgaggttg gacattggca aatttagcac
     6601 cgaaaatttc ttttgcgcgt tcaatagcaa gagtctctac aacgtctact acatcagttc
     6661 caccataata acggcgtcct gggtaaccct cggcatattt atttgtcaag atagaccctt
     6721 gagctgccat aacagccttg gaaactacgt tttccgaagc aattaactcg atattatttt
     6781 gttggcgttc ttcttctttg gcaatagcat tccagagatc agcatcatat gctttaaaat
     6841 catctttgtc aaaaatcata ggtcttctcc tttattgtgt gactagtcca ttagtttgat
     6901 tttacaataa gaaaatcaaa ctaaaagatg cgaataaacc gtttctgcat tttatcacaa
     6961 gtatagccaa ctttttcata aaatgcatga gcacccagac gatgattggc agaatttaag
     7021 cggataaacc cataaccaca tcttttggct tcttgttcca acccttgtag taaactttta
     7081 ccgatacctt gaccttgcgc ttgaggtgaa actgctaaag ctaagatatt aaatcctgct
     7141 ttggaataga gtgattcgta aacttcagcg tggacatatc caagtaagac atgattagct
     7201 gcatcctcat agccaagtag gaaatgatgg gaatcctgag acagtctagc tagttggcta
     7261 gccgtttcct ctggactaaa agtataaccc aaagcctctt ggttgatgtc acatatcgct
     7321 ttcacatctg tttcttgcaa atctcttagc atttcaagcc tcctcaaaag aaatctctgg
     7381 caaccgagca agaatatctt ctcgtttaat tgcgccttgg cgtaagattt tcaccttgtc
     7441 tccagacaaa tccacaatag ttgaatcctg tccagttaga aaagcatcgt cttccagacc
     7501 cagaacctct tggtcaaaat ccttcagaat ttgttcaaag gttacaccac ttgcctgacc
     7561 tgagatattg gcagacggcc caatcaaggg acctgtctct cgaattaaat ccagtgtgat
     7621 agggtgactg ggcatccgaa atccaatagt tgcaaggtca gaatttaccc aatagggaac
     7681 tcggtcattg gcttcgagaa taatggtcaa gggacctggc aaaaaggtct ctacaagttt
     7741 ttgtagataa gttggctgat tcttagaaaa gtgcaagata tcctcgaaag aggcgatatt
     7801 gagattgagt gccttatctc taggacgacg tttgagttgg taaacatggt caactgcttt
     7861 ttcatctaag gccttggcaa aaagaccata aacagtctct gtaggtagaa cgacagctcc
     7921 accattttcc aactcttgtc taatcctgtc catcatcaac cacaaccatc ctattttgac
     7981 caaattggtc tttgagtgtt cgaacttttt tttcaggaag atgttttcta aaaagttcgg
     8041 gaacactttg accttgcttg tatccaattt caaggtaaat cttaccacca tccttgagat
     8101 agtcttttgc atcttccgca attctacagt aaatagctag gccatcctcg tctgcaaaga
     8161 gagctagatg aggctccgaa tgcaaaacat tcaagcctac ctctgactca tcttcacgag
     8221 agatataggg tggattggat acaattatat catatttttc agaaatttct gcaaaacaat
     8281 cagatttttt aaaaaatata ttaagatttt gatcgctagc attctctgat gcaagctcta
     8341 aggcctcttg agaaacatct gctgctgtca ctgaccaatc tggtctattt tttgctagag
     8401 cgagagcaat agctccacta cctgttccaa tatccagaac tgagagattc gtctcaagat
     8461 tttcagttag aataagctcc actaactcct ctgtttctgg acgaggaatc aaaacccgtt
     8521 catccacctt taaatgcatt ccataaaaat ctgcctgtcc aatgatgtac tgagctggct
     8581 tgtgagctgc tagttgctgg taaatatctt ctacaaattg tttttcttcc tctgttgtca
     8641 cctcctgctg gagggcaaaa ataaagtctg taaaagatag atttttcaga ctacgataga
     8701 caaaagagag gctttccgct tcctctcctt gtcttatcaa ctcttcttca aaatttgaaa
     8761 ataattgagc taatttcatt atttgtttaa ttcttctagt ttttgtgttt ggtcataaag
     8821 caccaaggca tccacaactt cgtccaattt accagacaaa atcgtatcta gtttttggag
     8881 ggtcaagccg atacggtggt ctgtgacacg gttttgaggg aagttataag ttcggatccg
     8941 ttctgaacgg tcaccagtac cgattgtcga cttacgctca gcgtcttgtt catcctgagc
     9001 aatctgagca aagtggtcag cgacgcgtgc acggataatc ttcatagcct tctcacggtt
     9061 cttctgctgg gtacgttctt cctgcatctc aaccttgata ttggttggca agtgaacgat
     9121 acgaacggca gtcgcaacct tattgacgtt ctgtccacca gcacctgatg cgtggtaaat
     9181 atcaacacga agatcttttg gatcgatatc gtattctact tcttcgactt caggcatgac
     9241 aagaactgtg gcagttgagg tatgaacacg accttggctt tctgtcacgg ggacacgctg
     9301 cacacggtgg gcacctgatt cgtacttaag cttagagtat acagactgac ctgaaaccat
     9361 agcaaccact tctttaaacc caccgacacc attcatagag gcttccatga cttcaaagcg
     9421 ccagccttgg gcttccgcat acttttggta catagttagc aaatctccag cgaaaagtgc
     9481 cgcttcgtct ccaccagctg ctccacggat ttcaaggatg atattcttgt catcgtttgg
     9541 atcctttgga aggagcaaaa ttttcagttt ttcttcatat tcttcttttt cagccttggc
     9601 atctttgagt tcttgcttgg ccatttcttc caagtccgca tctccgcctg attccttaat
     9661 catctcttcg gcatcgacga tattttgaag gacttgttta tactcacggt aggctattac
     9721 ggtatcacga ttggaagctt cttcttttga aagctccata aaacgcttgg tgtctgaaac
     9781 gacatcaggg tcactcagca attctcctag ttcttcataa cggtcttcta cagcttgtag
     9841 ttgatcatag atgttcattt ttcttcattc tccttattga tttcaggggc aaaataatgt
     9901 ttacggcaaa ccgagatata ggtttcatta ccaccaattt ggatctgttc tccatcgtaa
     9961 acgggcagtc catcctgtgt tcgcaacacc atggtcgcct ttttcttgca atactgacag
    10021 atggtcttga tttcgtcaat cttgtctgct aaaagcaaga gatatttgga accttcgaac
    10081 aattcattgc gaaagtcatt tttcaagcca aaagccatga cgggtatgtc taactcgtcc
    10141 acaacacgag ctaggtcata aacatggtgg cgtttgagaa actgggcttc atcgaccaac
    10201 acacagtaag gtttttctgg taggcctcgg atatagccaa agatatccgt tgtttcctca
    10261 atcgcaaggg cagggcgttt catgccaatt cgactcgaca catagccaac accgtcacgc
    10321 gtatccagag ctgaagtcat aatcacaaca ccttttcctt gctcctcata gttataggcc
    10381 accttgagaa tctcgattgt ctttccagag ttcatggtcc cataacgata atacaactgt
    10441 gccatgtttc ttgcttcacg tccatttcta aatttttgct acattctagt atatcataat
    10501 tttcttaagc tttaaacggc aaaatgtggt aaaatggaag aaatcaaaac tagtggagga
    10561 agctattatg ccatttgtac gcatcgattt atttgaagga cgcacgctcg agcaaaagaa
    10621 agctcttgct aaggaagtaa cggaagcagt tgtccgcaac actggagccc ctcaatctgc
    10681 tgtccatgtc atcatcaacg acatgccaga aggaacttac ttcccacaag gggaaatgcg
    10741 tactaaataa gctagcttaa gcagaattgc ttaggctttt tcaatctcca agtagcattc
    10801 attgaagaaa tatcctaaat ttgttacaat ttgaaaagaa acttggagaa tttccaagaa
    10861 aagagctatt aattaaagga aacattatga ttacacgtga atttgatacc atcgctgcta
    10921 tctctactcc actaggtgaa ggggctattg gtattgtccg cctgagcgga acagacagtt
    10981 ttgctattgc gcaaaagatt tttaaaggaa aagacttgaa caaggttgcc agccacactc
    11041 tcaactacgg tcacattatt gatcctctga ctggtaaagt catggacgag gttatggttg
    11101 gggctatgaa gtctccaaag accttcactc gtgaggatat tatcgagatt aacacccacg
    11161 gtggtattgc ggtgaccaat gagattctcc agctagctat ccgtgaagga gctcggttgg
    11221 cagaacctgg tgaatttacc aaacgtgcct ttttaaacgg tcgcgtagat ttgacacagg
    11281 ccgaggcggt gatggatatc atccgcgcca agacagacaa ggccatgaac atcgcggtca
    11341 aacaacttga tggttccctt tctgatctta tcaataatat ccgtcaagaa atccttaaca
    11401 cacttgccca agttgaggtc aatatcgact atcctgagta tgacgatgtt gaggaagcca
    11461 ctactgctgt tgtccgagag aagacaatgg agtttgagca attactaacc aagctcctta
    11521 ggacagcacg tcgtggtaaa atccttcgtg aaggaatttc aacggctatc attggacgtc
    11581 ccaacgttgg gaaatcaagc cttctcaaca acctcttgcg tgaggacaag gctatcgtaa
    11641 ccgatatcgc tgggacaaca cgagatgtca tcgaagagta cgtcaacatc aatggtgtac
    11701 ctctcaaatt gattgataca gctggtattc gtgaaacgga tgatatagtg gaacaaatcg
    11761 gtgttgagcg ttcgaaaaaa gccctcaagg aagccaactt ggttctacta gtgctaaatg
    11821 ccagtgaacc actgactgcg caagacagac aacttcttga aattagccaa gataccaatc
    11881 gcattattct acttaataaa accgacctgc cagaaacgat tgaaacttcg aaactacctg
    11941 aagacgttat ccgtatttca gtccttaaaa accaaaacat cgacaagatt gaagagcgaa
    12001 tcaacaacct cttctttgaa aatgctggct tgattgagca agatgctact tacttgtcaa
    12061 acgcccgtca catttccctg attgaaaaag cagttgaaag cctacaagcc gttaatcaag
    12121 gtcttgagct ggggatgcca gttgatttgc ttcaagttga cttgactcgt acttgggaaa
    12181 tcctcggaga aatcactggg gatgctgctc cagatgaact catcacccaa ctctttagcc
    12241 aattctgttt aggaaaataa gaaaaatcca tgatccttca ttcggtcatg gattttattg
    12301 tctttattag taatctggtc ttaagacccc tgttacagtt gccttagttg cttcgtagtc
    12361 gccatctacg acaaccttga taatgcgttt ggcatcttct tctggtgctg gaacaagagg
    12421 tagacgagtg ggtccagctt caaatcccat atagttaaga attgccttaa ctggagcagg
    12481 acttggataa gagaagagag cattaacctt aggaatgaat ttacgctgaa ttgctgcggc
    12541 tttcttcata tcgctttctg caatggcagt aaacatctcg tgcatttcat ccccatttgt
    12601 atgagaggca acagaaataa ccccatccgc cccaaggttc atggcatgga aagcatctcc
    12661 atcctcacct gtataaatca agaactcttc aggcttgtgc tcaatcaagt aagccatatt
    12721 agccaagcta gtacattctt tgacaccgat aatatttgga tggtcagcca agcgaagcat
    12781 ggtttctgga gtcaattcga caactacacg ccctggaatg ttatagataa taattggtag
    12841 gtcagaagca tctgcaatag tcttaaagtg ctgatacatc ccttcttgag aaggtttgtt
    12901 gtagtaagga acaatagcaa gcccagctgc gaaaccacca aattccgcta cttctttgac
    12961 aaactcaata gagtcacgcg tatcattagt acctacaccc gcaatcaaag gaacgcgtcc
    13021 attgacaacc ttttgtacag ccgcaaacaa ctccaactcc tcatcgtggg tcaaagttgg
    13081 actctcagca gtcgttcctg cgagaagaat tccatccgta tgatgggcca ataaatgctc
    13141 aatcaaggct ggaatagcat caaagttaat agaaccatcc tcatgaaagg gggtaataaa
    13201 ggctgtaatg attttacatt cttttaaatc ttgataagac atgaaaacac ctctctattt
    13261 caaagaagga gttcatctga actcctaaac gatatgacta ttttaattca aatttcaatt
    13321 cggctgttgg acgaaccaat ccacgttcat gaagagtttc agcaatctga actgagttcc
    13381 aagcagcacc tttgagaagg ttatctgaaa caacccacat gtgaattcct ttttctgcat
    13441 ccaagtcttt acggatacga ccaacaaagg tatcacgcga accaactgca ttgatagctt
    13501 gaggatagat ttgatgagct acatcatctt caagaacagc acctgggaag gctgcgatag
    13561 ctgcttttac ttcttcgatt ggagccactt cttttgtttc gatataaaca gactcagagt
    13621 gagctgacaa gactggaata cgcacacatg ttgcagatac tgcaatgcta tcatcttcca
    13681 taattttctt agtttccttg gtcatcttca tctcttcgta cgtgtaatca ttatcagtga
    13741 aaacatcaat ttgtggaaga gcgttaaagg cgataggata atgtttcttg tcaccacctg
    13801 aaggcaaaat ttccgcatgc aaatcacatg gtttcacacc atcattcaag acttcacgaa
    13861 gttcacgttg tgtctcaaga attgctccca taccagcacc tgaaacggct tgataagttg
    13921 aaacaatgat acggtccaag ccccattttt ggcgaaccgg ctcaagagcc accatcattt
    13981 ggattgttga acaattaggg caggcaatga ttccgttgtg ggcatcaagt gcatgagcat
    14041 tgacctctgg aacaaccaaa ggaacatctg gattttgacg gaaataagat gtattatcca
    14101 ctactaccac gccagctttt actgcgtatg gtgcatactt agctgatgta gaactacctg
    14161 ctgaaaagag agcaatatca actccttcaa aagctgtttc agtcgtttct tcaattgtaa
    14221 tatcttgatc tttaaatttc aatgacttac ctgctgaacg tgcagaagca aggtaacgga
    14281 ttttatcgat tggaagtgtt gattcttcca acatttttat catctgagca ccgacagcac
    14341 ctgtcgcgcc gactacagca actgtatatc ccataaataa cctctttcgg aattttctaa
    14401 aaatttctat aatagaagta ttatactact ttttccatga attgcaaagc tttttcatca
    14461 ttttttggaa aataaaaatc ccagtcgcta gactagggac taagaggcat cttcatgtga
    14521 tgagcaggtt cacacaactc atcaaggtcc gctcctgcgt tatgacctcc ttatgctcaa
    14581 tagtagtccg aagactacct atcgactcat cgcatattct atattactag agatacttga
    14641 ttttgtcaat aagaaatttt ttcgatcgag tataacaaaa aactctcgta ttcaagagtt
    14701 tccctataca tatcatgcta attgccggga tcgaaccggc gacctcatcc ttaccatgga
    14761 tgcgctctgc caactgagct aaatcagctt acttaagaag tatactatat tcagaaaaac
    14821 ttgtcaagtt tccttagaaa ttttccatag gaaaaagcca ggtaagaact acctagctta
    14881 tcttcttcta tttacttaaa tcaattcgac gaccaatttt accaataata atcgccccaa
    14941 taatcaatga agcaaattca ccgattcctg ttgtaaacca agtaaggaag aatggtaatt
    15001 ctgctacaat atttaactct gcagcgatag taaacatgga aattgaaaag aggattgaaa
    15061 agaagaaatg atcttttcga atcaatccgt taaagaggta atccttgcta tattttgcaa
    15121 aaagccaaac acctaaactg aggaatacta aggttgaacc accaccaaca aagacatcta
    15181 gcagtccgaa gctaaagaaa ttagcaatca tacaaccgat ggtaactccg atgatgtact
    15241 taggattgta aaaagccata aagttcatca tttctgaaat acgaaactga taagcaccat
    15301 agctgatggc atttaggggc ggtgtgacag tcaaaacgac gtagatagca gcgacgattg
    15361 caatatctgc aatatcacga atagttaatt ttttcatctt ttctcctttg gcggttgccc
    15421 gcgtgtaata tgcttggtga aagaagctaa gcaccaaggg ttgctttatt caaccctact
    15481 agtatagcac aatagcctgc tttatgctat acttaacaca tgaaaattcc tattcaaaaa
    15541 ttttttaaca atgaaatctt agcctatctc ttttttggcc ttgcgacaac tctagtttcg
    15601 attctctcac gactagtcat ttatcaacta agtcatcagg aactcctggc tactgcccta
    15661 gcaaatatta tcggtatcct atttgccttt atcacaaatg atacgattgt atttaagcaa
    15721 aaaaagaaaa atagacttat ccgtttagtg aaattttctc ttgctcgcct ttctactttt
    15781 ctgttagact tgtttttaac ttttctcttt gtaacccaat ttcctcacat tatagggcaa
    15841 ttcgtaactg aaaacattga taagataaat gctattgaaa caataattgc acaaatattc
    15901 attattatca tcaattatat attgagcaag gcctatattt ttagaaaata atgctccatt
    15961 tatgagcctt ttaattgcct tctataatga tttaggatac aatgaaacac gaaacattga
    16021 aaggaaaaca gtatgttaaa aaatctaaaa tcgttcttgc ttcgaggaaa tgttattgac
    16081 cttgctgtcg gtgttgtaat tgcctctgct tttggtgcta tcgttacttc acttgtaaac
    16141 gacattatca ctcctcttat tttaaatccc gctttgaaag ctgctaaagt tgaacgtatc
    16201 gctcaacttt cttggcatgg agtcggctat ggtaacttct taagtgctat tatcaatttt
    16261 atctttgtgg gtaccgccct cttctttatt atcaagggca ttgaaaaagc acagaaactg
    16321 actggcataa agaaagaaaa aactgccgaa aaaaaaccaa ccgaattgga agtccttcaa
    16381 gaaataaaag ctctccttga gaaaaaataa tcgattaaaa ggatctagcg caaagctaaa
    16441 tccttttttc tttactcttt gggtaacttg cctgcttttt caagcatttt tttgatcaga
    16501 taaggcatct taacattctc ccgccctttt ttctcaatca gttttttcac aaattctggc
    16561 atttgtaaat cttcagattc agctaaaatg tttttcgtct cgtctgaagg aactaactca
    16621 tcaaaggtct cttcttctgg gagaaattcc ttaaactctt gattttcatt gactctaact
    16681 gtattgacca aagcatcaat caaacgagaa tctgtatttg gcattggtgg acgatggtag
    16741 tttaccccaa attcctggca taagtcataa cattctacat cattgtcaaa caagacctca
    16801 atatgctcac tgatgaaact aataggtaca aaaatataat ggtctggatg ttctgtctgt
    16861 tctctgagat actccaaaac atctggttta atccatggaa taccaatatc actctcactc
    16921 tgccaagtgt tggtatattg ttctgaactc aagcccagtt tttcagcgac tagcttgcta
    16981 ttttcgaaaa tttggtctat ataaggatca ccaaagtcca aggcaaaaat gggcacacta
    17041 tgggctgaaa agatgacttt aaagctgtct tgctttactt cttcttttaa aatcttagca
    17101 atttcatctg cccaatagtt taagagcact tcttcctgat accagtcctt aatgaccaaa
    17161 aattgaattt gtttgctttc taaaaatttt tcatagccca tgacagagta gaaagaataa
    17221 tggggctcca aaatcaagca gatacattct tcaacaccat cagtttccat ctgcttgatc
    17281 acgtctggaa taaagggacg agaaaatttg ttggcaaagt agataccgta ctcctcccct
    17341 aaacgttctt tgactaaatt gacctcctca cgtgtaatcc gctgcaaagg cgtcccaccg
    17401 atacgaatat agttgtcata gagagtctgg atttcgtggt cttggggtct aactccacga
    17461 cgaatgtttg taaagaattc tgctactcct tcaaaactaa tctcctctgg agatccaaag
    17521 gtcatcatta atatggcttt tttcatgtta tcatccttat gatattattt tctctatcca
    17581 ttctatcatg aaagaaaaaa atagtaaacg tttcctacgt ctactatttc ttttgctctt
    17641 ttgttttttt atctcgtctt ataattagga tgataaggac aagaagtaag aggacgataa
    17701 taaggagtag aaaggctaga atgtaaatcc aatgactggg aattccgtga tcgaaatacc
    17761 gtgttcctac tgcttcccca ctttcatcct gtgctacttt caccggtgca tccgttattt
    17821 tagctaaaag gatatgtcgt ccattagtta tgttaaggaa acatctcgct tgtacttggc
    17881 tttacttagc agatattgat agtaagcctg gtgttcctca tccttggaac tcaaggttcg
    17941 ataaatctcc gtgtcatagg catccacttc taaaatccca aaaatttcaa gaccacgttc
    18001 tcgaccattg tagtagatag aaccgtagcg atgctggtcg aagaattcct tatcagcaaa
    18061 tttcttaatc tcaccgaaca tagcccctga agccatagag tgtccgtaga tgatcgtatt
    18121 aaaatcagta aagttgggat taaagcgata gtcgagaaaa attgatccca ttatcgtata
    18181 atcgccaaag gcattgcggt caaggtattt gacattatcc tgactttgta gaagcggata
    18241 gtctaccttg gtcccatcaa ggctaatcca accgcaaaca tctttgttca agtgctgtag
    18301 ggtttcaaaa cctgtgctcg aagcatcctt ttcaatagga ttatagtgat catagtcact
    18361 tgcttctact actctctgcc aactaaaaag agctacaaaa acacagaaga ataccagaaa
    18421 tacgttttta aatcgcgctc ttttttgaac cgtcatcagc actcctttct atgcgagatt
    18481 tcttaaaagg aaaggaggcg ggacaaaacc gcctcttttc tattcaccct tagtcagtaa
    18541 aagggtctgc ttcttgcatt ttttttactc tctcttctac gacgtaggat caagtagagg
    18601 acaaggagta agaaaatcaa gagcaagaac aatacaaaca agataaggta ccaaatccat
    18661 agtgggattg atgagaggaa acgtccaaga gacgagtcat caaagacact gtatggaaat
    18721 ggttttgatt tttttgtatg gaaagtattt ttagggacgg tgtctgtaat ctttgcgact
    18781 acgatatgac gaccattggt cacatcgaga aaacaggtac tgagtaggat gatacgatca
    18841 ctcggtgaga gtgagatatc ccgcttgtgc atggcgactg agagcaggtg gtctagatag
    18901 gcctgctggc ggtcctcacc ctgtattcct ggatcataga tgttaaagtc ataggcatca
    18961 acctccaaca tctcaaagat ctcgagccct ttttccacac cattgtagta tatactaccg
    19021 taacgatgct ggtcaaaaaa ttcctgatca gcaaacttag ccacatcacc aaacatgacc
    19081 ccattttcta cgtggtgccc gtagataatg gtattaaagt cttcgaactt aggattattt
    19141 cgtgcatcga gaaagatagc gcctgtcgct gcaaactcac ctttggagtc cttgttgaga
    19201 tacttttcat tgtccttggc ttggactaag ggatagtcga tattggtgcc atagacattg
    19261 atccaaccga ggacttcggg attgagttct tggagtttgc tgaagcctga aaaactggcc
    19321 agctcatcct gttgcgtcgt gacaggtcga taagcttcgt actcacttga cgaagctaag
    19381 gagtagactt ggttggaatc ccaaagggcg tagaaaccaa agagaaagat caaagctgca
    19441 aaaatgagca gcaagtgatt gatcacccca tccacagcaa gaacgagacg cctagacaga
    19501 ctcttttttg gtttctcacg cttggttttc atcatctgcc cccagccgtt taggcttctc
    19561 tacgtttttt agacaagaca acaaatccag ccaaaccaag accaatcatc aaaatgaatg
    19621 gaaggttatc aatcaagaga ccagtaggag taacgtcgtc gattttgtta gtaactttgt
    19681 tgtcgttttt cttttcacct atgaggatat ctgttaatgt aaaatctaca tttttttgtc
    19741 cttgagatgt ttgttctgca ccatttgtag tataaattga tgaatctgta taacctgcta
    19801 ctccagtttc agttactgta tatttagaac ctgctggtag ttgttcaact gtaaatgttt
    19861 caccatcttt aagagtaaaa ttgtactcaa ctgtatctgc tggggtcact actgccaaca
    19921 cctctgactt agatccatgt tttactataa tattcgtaac aggggtttct gctgttttat
    19981 ttgtacttgg aagttgaatc ttgatatgga attggaaatc tcttgtttta tcccctgaag
    20041 ctccatcaac ttttttagta attgttaatg ctttcgcatt ggggtctact tgactcggat
    20101 catcaggatt aggctcctta cttgcgtctt tggtatatgt gttatcaaat aaattataaa
    20161 cgccttgttc acttggttct actttagggg cgttagattt attattttcc ttaaagtata
    20221 ctgatgaaat atagacacca ccatttactt tattcttaac aataacgtgc atttcatatg
    20281 tacgtttgtc gtatctcatg gcatcaattg ttttaccatt tttggtaatc gcctgccatc
    20341 cagtttttgc ttccgctaca tcataaacgt attcaccagc atggccataa gcaactcccg
    20401 aaaaaatgtc ttctgttgct ttttgaatct tatcagcagt tgggtgatca tttttattgt
    20461 attctacatt tctatctgga attgcaactc cggtttgata tggcgcaccg ttagaagatt
    20521 gtcctgtttt ttctgtaaac ttaaatgtaa atgtcgctgt tggtgttgtt attccctctg
    20581 caatattcaa cgttttatta atcttcacaa cagcattatt ttcaccattt gctttggtta
    20641 ttgctgaatt atcatccgca aaagtcggga cacctctgaa tacggacaaa gcggttatag
    20701 ctgcaatgct tgcagtgaat agctttttaa agaatgtttt tttcatgatt atttcttttg
    20761 tttttttatt ttcttttttc attatgatca tcaaaagcct cgtcttctaa tgactgttac
    20821 aactttgcct tgagtatcct gtatagggat ggttccaaaa gcacgactgt ctacagccgt
    20881 tgttcgattg tccccgagga caaaaagttg tcctgctggg actttcatcg ggaaggttgc
    20941 cccttcctta tagagcagcg tttctttgta gatatcttgc tcttgttgag gagaaccgtt
    21001 gatgatgaga ccattttcgt ttatatcgat tgtacttcct tcggttgcta tgacacgcgc
    21061 cactctttcc ttacctttat aactatagac tagcaaatca ccaatcgaat agcgtttatc
    21121 caacctataa tagacgacca agtcgccatc ttttaaggcg ggcttcatgc catcgtcatt
    21181 gtatcttaat aatccaaaga cgaaaaagta aaggatggct agtacaaatc caaccatcag
    21241 aagtttactg actaagtaaa ggatatctcc ccagacactc ggcggagact tatcccgatt
    21301 gacttgtgtt actggtttct tatgtttctt tttaagcagc atcacttcct cctattcacc
    21361 acaaggtgac caagtaagat gataaagaag atccctccta gaggaagaac gactccaagc
    21421 acgagagtgc tactcaagaa gtcaattccc gtttcaggta cgctgttttt attattcgtg
    21481 actgtcgcag acttatttgc atcaagagtt ccttcttttt tatcatagga cacctgatac
    21541 ccacgagacg aacttgcttc ttcttcgata ctataacgag catttagagg aaggtcgaga
    21601 atcttgatgg ttttatcttt ctttagatca actgtcgcct taccattggt gaattgtagc
    21661 gttgtttttt gattatttac tattgcacta tacgatccat tcaatggttt attttgcgca
    21721 tcctttacgt taatggtaat cttaaaggat tgcagaagat tagcaaaagc acctgtaact
    21781 ttttttgtga ctgaaagtgt cggaagtctg tggttggtga cgattgtttg aacatcctct
    21841 gacaaagtcc cctcttgttt ttcataggtg acatgatatc ccgttctaga gttctctact
    21901 tcttccacct tatagtgggt atcacgaggc agataactga gggcagtttc ctgactattt
    21961 ttgagagaaa tctgtgcttt cccgttagtc actgttgtat tcccaaactt gccgttaatc
    22021 ggcttgccat ccttatctga aaaggtaaca ttaattgtga aagatttatt aggtgattgt
    22081 tcaccttcta ggattttctt tacggtgaga cttggaagct gtcggtaaat aactttgaag
    22141 gatggtttct ctttcgtacc tgtcttttga acttcgactg tgtatcccgg agcgtctggt
    22201 gctttcagtt cgtagtcata tcccttagct acctttgcaa aactagtatt ttcagtaaaa
    22261 ctattcgttt gaactggact agtgaccttt cgataggaat cctttatact tccatctttc
    22321 ttttggttta agtttaattc gacactaggt ggacgatttg ctgatggatt tgattttcca
    22381 tccacacctt tccactcaat ctctacagga accgtcaatg gatctgacgg cttgaaagtg
    22441 ggcttctcag aatagtcttt tattttggta cgtgaggtcc caataccata ggaataggca
    22501 acttttgccc ccttgttgga gtagagttta gtagcatcgg cttcttcggc atcatcacta
    22561 gtaagtgtct tatcacccgc aatcgcatca aatgcctctt ggctagaggt gacagtaaac
    22621 ttgagaacgt acttggcgtc atcctccaaa gtgtaactcg gattaaactt ggctgttact
    22681 tccactaatc cctgttcgtt cttcttagtt tcaatcgtaa cttgattgtc attcagttct
    22741 tgctcgttac catccttgat tttgacgaca cgaaggtgtg aagcatcacc aggtaacagc
    22801 tgcacgtact tggacaagac atctgatata gttacatggt gtacgcctag aggtagaatt
    22861 ttatctgtga tttctttgaa tttttgttgc aagtcatttt cattattggc agaaaatatt
    22921 tcgttgggga ttccagaatt ataaccactg atatatcctt taagagatgt gatactatcg
    22981 tttgaaccta tataatatct gaatttgatt gaataaaagc catctatttt tggagctatt
    23041 aaactagata tattcagcat tcctctttct aaaccagagg taaaccaata tggagtatca
    23101 atcatacgtc ccacatttgg attagaataa tagttatata ttgttctccc actattagac
    23161 tcgtaataca tattagcttc gccatctgac agcagaataa ctactttttt tgccccagcc
    23221 cttgcacttt gcaacaatct ttgagcttca gttaacccag catttatatt tgtcccagtg
    23281 ccaatgcccg cgtccatacc ataagaacga ctagagtcag caattgttaa cgaactaaca
    23341 atattttttg agctattaga atccgtgctc caagatacta aagttttagc atcatcatat
    23401 gaagagatat ttgaatacca accagctcaa tttggccaag ttccatattg ataactcaga
    23461 taatattcat tataataacg gtcattatac tgattatcaa tctttccggc aaaaccaact
    23521 atagacagac ggttttggga attagaaaga attgtatcaa tgagcccctg acgaccattc
    23581 acacctttca gtgtatgttt tagtgcttca atcctactaa tgtatcgtct actagagtaa
    23641 gaccacacat ctcgctcttc catactccct gaaagatcgg caaccaagac tacatccaag
    23701 ggttctgact gggtctccgt tcccagttta gatgtgatat ccagtgacaa ctcatactgg
    23761 tctttttgcc ctgatatcgg agtaatcgtt ttgtgcagag ttgtctgagg ttcagttatt
    23821 gaatctgcac gtaaagaatt aattggtgca cacaaaaaaa gaatagcgag aaagataact
    23881 aaactactgg taaaatattg aatcttctta aaatcatatt gaacgttcat gctatctccc
    23941 ttgctagaat atgttttaat ctgatactat ataaatctga gacttccata agataattgt
    24001 ataataatat taacttcgtg tcaattaatg tgtttgaaaa catgttatta taaattacaa
    24061 aaaagtatga ttcttctttg tttttcaact ttttctgtgg taaaatggaa aaaatagtaa
    24121 aaaatttcat aaaataaaga tgcatatatt tattctaatc gctcgaaaat ttcttttgaa
    24181 agtcttctga atttgaatta ttatattttt tcaaaattca taaaatttct caaatcatat
    24241 ttttccgaag ttttgtattc tattttatga taaaaaagga gtttttttat gacttatcca
    24301 aatctcttgg accgcttctt aacctacgtt aaggtcaaca cgcgctctga tgaacactct
    24361 actactactc caagtacaca gagtcaggtt gacttcgcaa caaatgtcct aattcctgaa
    24421 atgaaacgtg ttggactgca aaatgtttac tatctaccga atggttttgc tattggaacc
    24481 ttgccagcca acgatccgtc tttaacacgt aagattggtt ttatatcgca catggatact
    24541 gctgatttta atgctgaagg agtcaatcca caggtaattg aaaactacga tggtggtgtg
    24601 attgaactag ggaattctgg tttcaaactc gatccagccg acttcaagag tcttgaaaaa
    24661 tatccaagac aaacactcat cacaacagat ggaacaacct tgctaggtgc tgatgacaag
    24721 tcaggaattg ctgaaattat gacagccatt gaatatctaa ctgctcatcc tgaaattaag
    24781 cactgtgaga ttcgtgttgg ttttggtcca gatgaagaaa tcggtgttgg tgccaataaa
    24841 tttgatgcag aagattttga tgtggatttt gcctacactg ttgatggtgg tccactaggt
    24901 gaacttcagt acgagacttt ctcagccgct ggtgctgaat tgcatttcca aggccgtaat
    24961 gtccaccctg gtactgccaa agggcagatg gtcaatgccc ttcagctagc aattgatttt
    25021 cataatcaac ttccagaaaa tgaccgacct gagttaactg aaggttacca aggtttttac
    25081 catctaatgg atgtgacagg tagtgttgag gaggtgcgtg caagctacat cattcgtgat
    25141 tttgaaaaag atgcctttga agcgcgtaaa gcatccatgc aatctatcgc tgataagatg
    25201 aatgaagaac ttgggagcga ccgtgtcact ctcaacttga cagaccagta ctacaatatg
    25261 aaagaagtca ttgaaaaaga tatgactcca attaccattg ctaaagccgt tatggaagat
    25321 ctaggtatca cgcctattat cgaaccaatc cggggtggaa cagacggctc taagatttcc
    25381 tttatgggaa tcccaactcc gaatatcttt gcaggtggcg aaaatatgca cggacgtttt
    25441 gaatacgtta gccttcagac tatggaacgt gcagttgata ccatcattgg catcgtagct
    25501 tataaaggct aaaaagacga ggtggctcag ctacttcgcc tttcttttta ttctactggt
    25561 ttttcttgat ttccagtagt tgtagaagat tctgttgttt cattttctga agttgattca
    25621 gcaggtttag aatctcttgt attgcttggt ttgttttcgt cgctagcagt ttcaatgtta
    25681 gattctgcag ttgcgtttgg ttggttctca gcactggtgt tatcactatt tgcttcagca
    25741 tttcttgctg gacttgtttc ttcacttgcg ctaacttttg actggatttg atgattcaaa
    25801 actagaatag cttttgtcga ttcaagtaaa gctgttttgt ctttactatt agcagaaagt
    25861 tgatctaata atgcatccac cttatcaaag tccgcatcag atccattatt actttctaaa
    25921 taagagtgaa gcgacatgag aatatcgtag agtttttgat agagtacaag tgtctgagaa
    25981 tcttgctcag cattttcctt ttcttgttga agggcgctag cgatacgagt caaaacatct
    26041 tttacctgac tgtttacttc atccaagtct gcatcagcct tgtttgtggc agcttttaga
    26101 ttttctactt cttctgccaa ggattgtctg attccttctt catggatttg ttccaagagt
    26161 tgatttgcct tgttcaaaag actttctact tcttccttgc tatctgtcgc agattattgg
    26221 ttgctatcta ccatgtactc ctaaaacagg agagttataa tccaagatta caaggcctta
    26281 cagaaataag aaatccagat aagacaatgt tcgtccaaga cgctattcgc ttcgcacagc
    26341 agcacggatt caatatgctt taattttaaa gtttaggtgt caagacctct ttttagtgtg
    26401 cccaaaattt agagaagtaa tcaatcaact aacttttatt tttttcaaac tttcagtaaa
    26461 ctgacctaaa gctaactcaa tctgtctttg tagatgcttc tgctatcagc tagaagttga
    26521 tctacttttg ccaagactgc cttctcatca aaagttccag gttgatagtt ggattgcagg
    26581 gatggaatct tgtttttcaa agccgcttca tatcccttag tttgaacctt gatgtagtga
    26641 ttgtggtcgc catgaggaat cacaaaacct tctgaatctt cacttataat tcgattggca
    26701 tcaaaaacca taaccatctt cttcctcatg gtggacatgt agtgacggat tacttaatac
    26761 agaactagaa gaacttccta cctcttccgt gttagagtgt gatgggggat tgttaagaga
    26821 tgacttagga atatagtgat agtgttcccc atgtcttact atataagcat cacctatatc
    26881 tctgacaata tcattagggt taaagacata tgtggctgct aattcacctg ccgacaagtc
    26941 actctcagga atgaaatgat agtgaccacc atgtggtact attagtagat tgaaatagaa
    27001 tatgagcaaa ttgataaggg gattttaaag taatttctaa caatgattta gaaactatga
    27061 tgtgctattc taaattcaac tcactatata taaccatcat cggtagtata acgtccctgt
    27121 aattttgcta cagatacttc tgcactagct cctttatcgt ctttaccatg ttcttgtttt
    27181 tggcgattga tttcatcttt tgttcgtaca ttttctgcat gagcttgatc tttaaggtaa
    27241 acataatact ttccatctac cttaataata tatcctccct taacctaact gacaatatct
    27301 tgatctttcg gctgatagtt gggggctttc attaatggct cttcactaaa gagcgcatca
    27361 aaaggaactt taccattata gtagtgataa tgatcgccat gagaagttac ataaccttga
    27421 tctgtaatct taataacaat ttgttttgct tgaattcctt ctttttgact aacctagtct
    27481 ggagtcaaat tttcagtctt cttagtgtct ttattactgt ttacatatga aacacgattt
    27541 ttatctgtat tggcctgtta gctatgttgg ttcagagcat aaacacacag acttaaggaa
    27601 aggataacaa cagatccagc tgctatatat ttctttttaa atttcataat tacctcattt
    27661 ctataattat ttatatgatg tcttcattat taaatgatta tagaaattaa ttaaccaatt
    27721 aattaactag taaatattcc acctcttttt aagttgtatg tcaagaaatt ttatatatta
    27781 ataataaaat gaaattctcc caaagtcaga gttttatttc taacttttga gagaacttca
    27841 tttttgattc agactttttc tactgctatt ccttacgcta tgagatcaga taaattcttt
    27901 tttatcactt ctccacttgg caatcttaat tcaatcgttc catccatatt gaatataaca
    27961 ctatctaagc ctaatccgta actagctgta aatttttcta atttttcttg tacaggatct
    28021 actgctggag cttcctctaa tgctggatct aacatagggt cactccccac attcccttct
    28081 ggattcaaca ttccattatc cgttgagttt tctggtttta caggtttttc gtttggtgcc
    28141 tctggtaaag aatctgctgg tttattttct gttggttggt tctcaactgt tccagtagat
    28201 acttttccat tttcagatgg tttattttca ccatttcctt gaggtgcttc tcctgtaaaa
    28261 tctgccatat tctttttaat gacttctccc gatggtaaat ataattcaat tgttccgtcc
    28321 atattaaaca agacattttc tagcttcatc ccataacttt cagcaaattt tgctactttt
    28381 tcttgtacag gatccactgt aggaacttct tctaacgttg aattactagt actattccca
    28441 gtttcagaaa gtttttcttt ttctaccttc tcactagtct ttggttcttc taccttttca
    28501 tcaagttttg agttttcttg tgctttattc cttttaaatt gtggtagaat acttggttta
    28561 tcagtttgat tttctttttc caagataggt acttccacaa tataagtcga ttgattgtcc
    28621 aaataagcat ttgccatgaa ggttacagga attttatttc cggccgttct ggttgttcct
    28681 tggtttaatt tcggaatcgg taatttgatt tcaccaactt tatagttatt ttctaaataa
    28741 gcatttccat gaaattcatc aaacactctg actaaagcat cagttccttt aggcactgca
    28801 aattgagggt tcactcttaa ataagtatcc cctgcatgga aaggatagaa aatcgtttga
    28861 ctggccattt tgtaagctaa agaggttgga actgtaaatg taccatcata acttacttct
    28921 ggataatctt ttgaagcgat agtatactta aatgtttgtc ctggtaaata aggttgatct
    28981 aattcaaagt ttgcaatatt ccctactcct tctccaaata ctttaccaga tactttctcc
    29041 aatacttttc catctggtgt tattaatttt actagcatat tgatacctaa ttttttctcc
    29101 aattcaggcg gaaaactaaa agaaacgcgt ttttgaccat tggctagagt aaagttttga
    29161 ttattaaacg tactattttt taacaaatta acaacattcg ttaattcttc tccagtataa
    29221 actttattcc cttctttttt agcaactcct tcttcgggtt taaacagttc atagttactg
    29281 tgagaatgac caattccaac cggtttatgt tcatcaatcg gatctgcatg atggtgatct
    29341 ccatgcggat aaataatcgc atttttttct ttattcacga caatactttc acgtttgaca
    29401 ccatattgtt tcataatgcc agcaattttt tcttcgattt ttttatctaa atctttcatt
    29461 tctttggcat tacttggata atcctgttca tgagatgaca aagaatctaa tccattatga
    29521 ctagttttaa cttcctctaa atgtttttgc gcagccttaa tttgctcttc tgtcaagtcc
    29581 ttcttgaaga aataatgatt gtggtctccg tgactcatga caaaacctga ttcatcttca
    29641 gcgataatac gattagcatc aaatccgtat ccatcttctt catgtttctc atgtgaagtt
    29701 cctggattga ttggaagaga tggagaaggt gttgctagac tattgtttgg aagagtcggt
    29761 tgcccaattt gatttgattt tggaatgtaa tggaaatgat caccatgtct tacaatataa
    29821 gctgtagccg tttcttcaac gatatctttt ggattaaaaa tataaccatc agatgctgaa
    29881 gagagctcct tacttgtcgt taaagaagaa ggattgcttg aaagactgcc tagactagac
    29941 actacttcat taggttttgc atttgtagaa actgtagaac cagttccact gataggcacc
    30001 attctggcaa tcttttcttc taaggcagaa agcttgctgt aaggaataaa gtggtaatgg
    30061 tcgccatgcg gaatcgcaac tccatttggt gtacgactga taatcttagc agggtcaaag
    30121 accaggccat ctgattcact gtaacgttgg gcgctaggtg aatcatagag ttccttcaaa
    30181 agactctgga gattttcaga tttatttgct ggcttgctag ttgatccttt tgctacagat
    30241 tgcgtgttat tgtcactagc tgttgaagaa tagcttaact gactcggttg catatttttt
    30301 ccagccagat gtgctttagc tgctgctaat tcactagcag ataaatcgct tttgggaatg
    30361 tagtgatagt gacctccatg aggaacgata taagcattac ccgtatcttc gataatatca
    30421 gctggattaa agacataacc atcatttgtc gtatatcgtc cctgagacct tgctacagca
    30481 acattagagt taaccttctc attatctttg acatgttctt gtttttgacg attgatttca
    30541 tctttagttc gaacattatc agcatgagct gcatctttca ggtagacata atattttcca
    30601 tcgaccttga tgatataacc acccttgact tcattgacaa tatcagcgtc tttaagttga
    30661 tagtttggat ccttcatcaa gagttcttca ctaaagaggg catcataagg aactttccca
    30721 ttatagtaat gatagtggtc accgtgtgac gttacatagc cctgatctgt aattttgatt
    30781 acaatttgct cggcctgaat tccttctttc tggctaatct ggtctggtgt caagttttca
    30841 cttttctgac ttgactggct gccatctaca taagagacac gattattgtc cttattttcc
    30901 tgcgaacgat gctggtttag tgcataggca catagactca aggatacgat aacagctgat
    30961 ccagctgcta tatatttttt actgaatttc ataaatccct ca
//
LOCUS       DAVBEM010000023        30864 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVBEM010000023 DAVBEM010000000
VERSION     DAVBEM010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30864
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.023"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(<1..83)
                     /locus_tag="VQ548_001064"
     CDS             complement(<1..83)
                     /locus_tag="VQ548_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET2653925.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEE"
     gene            78..332
                     /locus_tag="VQ548_001065"
     CDS             78..332
                     /locus_tag="VQ548_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET2653926.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIGAEAIRRNCERGAIFSGKIKHHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            676..2010
                     /gene="trmFO"
                     /locus_tag="VQ548_001066"
     CDS             676..2010
                     /gene="trmFO"
                     /locus_tag="VQ548_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HET2653927.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRIFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEAIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            2094..2831
                     /locus_tag="VQ548_001067"
     CDS             2094..2831
                     /locus_tag="VQ548_001067"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HET2653928.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            2840..3397
                     /gene="frr"
                     /locus_tag="VQ548_001068"
     CDS             2840..3397
                     /gene="frr"
                     /locus_tag="VQ548_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HET2653929.1"
                     /translation="MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRIHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVV
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            3457..4311
                     /gene="cvfB"
                     /locus_tag="VQ548_001069"
     CDS             3457..4311
                     /gene="cvfB"
                     /locus_tag="VQ548_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HET2653930.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTSLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            4320..4535
                     /locus_tag="VQ548_001070"
     CDS             4320..4535
                     /locus_tag="VQ548_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HET2653931.1"
                     /translation="MRKSFYTWLMTERNPKSNNPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            4621..5589
                     /locus_tag="VQ548_001071"
     CDS             4621..5589
                     /locus_tag="VQ548_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HET2653932.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMALVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            5769..6269
                     /locus_tag="VQ548_001072"
     CDS             5769..6269
                     /locus_tag="VQ548_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2653933.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            6272..6532
                     /locus_tag="VQ548_001073"
                     /pseudo
     CDS             6272..6532
                     /locus_tag="VQ548_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(6899..8010)
                     /gene="ald"
                     /locus_tag="VQ548_001074"
                     /pseudo
     CDS             complement(6899..8010)
                     /gene="ald"
                     /locus_tag="VQ548_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253293.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            8187..8756
                     /locus_tag="VQ548_001075"
     CDS             8187..8756
                     /locus_tag="VQ548_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2653934.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            8824..9474
                     /locus_tag="VQ548_001076"
     CDS             8824..9474
                     /locus_tag="VQ548_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HET2653935.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTSVKETNLQ
                     AEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            9458..11698
                     /locus_tag="VQ548_001077"
     CDS             9458..11698
                     /locus_tag="VQ548_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HET2653936.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSLQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNEWLLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIKKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            11878..12066
                     /locus_tag="VQ548_001078"
     CDS             11878..12066
                     /locus_tag="VQ548_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653937.1"
                     /translation="MTVTKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGGY"
     gene            12098..12685
                     /locus_tag="VQ548_001079"
     CDS             12098..12685
                     /locus_tag="VQ548_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2653938.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            12689..13864
                     /locus_tag="VQ548_001080"
     CDS             12689..13864
                     /locus_tag="VQ548_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653939.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWKDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIIFLLLGILFIERWGSSQKKRIF"
     misc_feature    14038..14169
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            14185..14715
                     /gene="infC"
                     /locus_tag="VQ548_001081"
     CDS             14185..14715
                     /gene="infC"
                     /locus_tag="VQ548_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HET2653940.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            14748..14948
                     /gene="rpmI"
                     /locus_tag="VQ548_001082"
     CDS             14748..14948
                     /gene="rpmI"
                     /locus_tag="VQ548_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HET2653941.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            15000..15359
                     /gene="rplT"
                     /locus_tag="VQ548_001083"
     CDS             15000..15359
                     /gene="rplT"
                     /locus_tag="VQ548_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HET2653942.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            15417..15797
                     /locus_tag="VQ548_001084"
     CDS             15417..15797
                     /locus_tag="VQ548_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2653943.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            16047..16847
                     /locus_tag="VQ548_001085"
     CDS             16047..16847
                     /locus_tag="VQ548_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HET2653944.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVNQRVCEDGPVFRTGTVVL"
     gene            16810..17796
                     /locus_tag="VQ548_001086"
     CDS             16810..17796
                     /locus_tag="VQ548_001086"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HET2653945.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            17838..19739
                     /locus_tag="VQ548_001087"
     CDS             17838..19739
                     /locus_tag="VQ548_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HET2653946.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     AKNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWL
                     DKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIP
                     VASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINN
                     SLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYL
                     SAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMK
                     INEKLGGKD"
     gene            complement(19800..21455)
                     /gene="pavA"
                     /locus_tag="VQ548_001088"
     CDS             complement(19800..21455)
                     /gene="pavA"
                     /locus_tag="VQ548_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HET2653947.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPLANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            21560..22057
                     /gene="ybeY"
                     /locus_tag="VQ548_001089"
     CDS             21560..22057
                     /gene="ybeY"
                     /locus_tag="VQ548_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HET2653948.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLGYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            22038..22433
                     /locus_tag="VQ548_001090"
     CDS             22038..22433
                     /locus_tag="VQ548_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HET2653949.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            22450..23349
                     /gene="era"
                     /locus_tag="VQ548_001091"
     CDS             22450..23349
                     /gene="era"
                     /locus_tag="VQ548_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HET2653950.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPDRFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            23398..24222
                     /gene="mutM"
                     /locus_tag="VQ548_001092"
     CDS             23398..24222
                     /gene="mutM"
                     /locus_tag="VQ548_001092"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HET2653951.1"
                     /translation="MPELPEVETVCRCLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQGCVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            24222..24827
                     /locus_tag="VQ548_001093"
     CDS             24222..24827
                     /locus_tag="VQ548_001093"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HET2653952.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFWQEIILENGELNRPLLASLIFSNPDEREWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            24814..26013
                     /locus_tag="VQ548_001094"
     CDS             24814..26013
                     /locus_tag="VQ548_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HET2653953.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            26013..26162
                     /gene="rpmG"
                     /locus_tag="VQ548_001095"
     CDS             26013..26162
                     /gene="rpmG"
                     /locus_tag="VQ548_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2653954.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            26202..26435
                     /gene="secG"
                     /locus_tag="VQ548_001096"
     CDS             26202..26435
                     /gene="secG"
                     /locus_tag="VQ548_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HET2653955.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            26537..28891
                     /gene="rnr"
                     /locus_tag="VQ548_001097"
     CDS             26537..28891
                     /gene="rnr"
                     /locus_tag="VQ548_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HET2653956.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSHSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            28854..29321
                     /gene="smpB"
                     /locus_tag="VQ548_001098"
     CDS             28854..29321
                     /gene="smpB"
                     /locus_tag="VQ548_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HET2653957.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            29337..30197
                     /gene="tehB"
                     /locus_tag="VQ548_001099"
     CDS             29337..30197
                     /gene="tehB"
                     /locus_tag="VQ548_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HET2653958.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEDVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            30270..>30864
                     /gene="coiA"
                     /locus_tag="VQ548_001100"
     CDS             30270..>30864
                     /gene="coiA"
                     /locus_tag="VQ548_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HET2653959.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQG"
BASE COUNT         9168 a         5715 c         7071 g         8910 t
ORIGIN      
        1 atctcttcaa aagtcgtgcg ctgaacacca acaagacgct taaatcgtgc atcagttagt
       61 tgtttacttg cttcataatt catagaacta ctataccata ttttgtttcg caggaagtct
      121 attggaaagt aagaaatatt ggagctgagg cgattagaag aaattgtgag cgtggtgcta
      181 ttttttcagg taaaataaaa catcacgaag attctcagtt taaaggagac cactatgttg
      241 aatgttatgc tgttttagat aatacggtta tagcaagaga tagaataaca gtccctatcg
      301 atccgttatg tggaaaagat tttatagagt agcatataat tgattcttaa ctggaatact
      361 ctctatctct ttacatcaag aaaatgacta aacagggaag tttgccttct tccctttttt
      421 tgttatacta gtagaagaaa aaaatagaaa gatttgtggg agtgaaaaag tccgggggac
      481 tttttcagct tgagccaaga aattcgagag cgaggaaagt ccgggggact ttttcagcct
      541 gagccaagaa attcgagagc gaagtaagtc caatggactt tttcagcctg agccaagaaa
      601 ctcgaaagct cgtaagtctg attggctttt tcaatgtgaa tcttaacttc acactcccaa
      661 agaggtatta gtgtcgtgtc tcaatcttat atcaatgtta tcggtgctgg tttggcaggt
      721 tctgaagcag cttaccaaat cgcagagcgt ggtattccag ttaaactata tgaaatgcgt
      781 ggtgtcaagt cgactcccca gcataaaaca gacaattttg ctgagttggt ttgttccaat
      841 tctttgcgtg gggatgcttt gacaaatgca gttggtcttc tcaaggaaga aatgcgtcgc
      901 ttgggttctg ttatcttgga atctgctgag gctacacgtg ttcctgcagg tggtgccctt
      961 gcagtggacc gtgatggttt ctctcaaatg gtgaccgaaa aagttgccaa ccaccccttg
     1021 attgaagtgg ttcgtgatga aattacagaa ttgccgacag atgttattac ggttatcgct
     1081 actggtcctt tgacaagtga tgccttggct gaaaagattc atgcccttaa tgacggtgat
     1141 ggtttttatt tctacgatgc ggcagcgcct attatcgatg tcaacactat cgatatgagc
     1201 aaggtctacc tcaaatcacg ttatgataag ggagaagcgg cctacctcaa tgcccctatg
     1261 accaagcaag aatttatgga tttccatgaa gctttggtca atgcagaaga agcaccgctt
     1321 aattcttttg aaaaagaaaa gtactttgaa ggctgtatgc ctatcgaagt catggccaaa
     1381 cgtggcatta aaactatgct ttatggccct atgaagccag tcggtcttga gtacccagac
     1441 gactatacag gacctcgtga tggagaattt aaaacacctt atgcggttgt gcaacttcgt
     1501 caggacaatg cagctggtag cctctacaat attgttggtt tccagaccca cctcaaatgg
     1561 ggagaacaaa agcgtatctt ccaaatgatt ccgggtcttg aaaatgcaga gtttgtccgt
     1621 tatggtgtca tgcatcgcaa ttcttacatg gattcaccaa atcttcttga gcagacttac
     1681 cgttctaaga aacaaccaaa tctcttcttt gctggtcaga tgacgggggt ggaaggctat
     1741 gttgagtcgg cggcttcagg cttagttgcg ggaattaacg cagctcgtct cttcaaggaa
     1801 gaaagcgagg ctattttccc cgagacgaca gcgattggaa gcttagctca ttacattacc
     1861 catgccgaca gcaaacattt ccaaccaatg aatgtcaatt ttgggatcat caaggagttg
     1921 gaaggcgagc gtatccgtga taagaaggct cgttatgaaa aaattgcaga gcgtgccctt
     1981 gccgacttag aggaattttt gactgtctaa tttttttgaa agaattgctc atgatactat
     2041 aaaaatctta gaaattgtga taaaataggt aggatgaaag aaggagagtg aaaatggcga
     2101 atcccaagta taaacgtatt ttaatcaagt tatcaggtga agcccttgcc ggtgaacgtg
     2161 gcgtagggat tgatatccaa acagttcaaa caatcgcaaa agagattcaa gaagttcata
     2221 gcttaggtat cgaaattgcc cttgttattg gtggaggaaa tctctggcgt ggagaacctg
     2281 cagcagaagc aggtatggac cgtgttcagg cagattacac tggaatgctt gggactgtta
     2341 tgaatgctct tgtgatggca gattcattgc aacaagttgg ggttgatacg cgtgtacaaa
     2401 cagctattgc tatgcaacaa gtggcagagc cttatgtccg tggacgtgcc cttcgtcacc
     2461 ttgaaaaagg ccgtatcgtt atctttggtg ctggaattgg ttcaccatac ttctcgacag
     2521 atacaacagc ggcccttcgt gcagctgaaa tcgaagcgga tgccatcctc atggctaaaa
     2581 atggtgtcga tggtgtttac aatgccgatc ctaagaaaga taagacagct gttaagtttg
     2641 aagaattgac ccaccgtgac gttatcaata aaggtcttcg tatcatggac tcaacagctt
     2701 caaccctctc aatggacaac gacattgact tggttgtctt caacatgaac caatcaggca
     2761 acatcaaacg tgtcgtattt ggtgaaaata tcggaacaac agtttcaaat aatatcgaag
     2821 aaaaggaata agaaagaata tggctaacgc aattattgaa aaagctaaag agagaatgac
     2881 ccagtctcac caatcacttg ctcgtgaatt tggtggtatc cgtgctggtc gtgccaatgc
     2941 aagcttgctt gaccgtatac atgtagaata ctatggagtt gaaactcctc ttaaccaaat
     3001 cgcttcaatt acgattccag aagcgcgtgt tttgttggta acaccatttg acaagtcttc
     3061 attgaaagac atcgaacgtg ccttgaacgc ttctgatctt ggtatcacac cagctaatga
     3121 cggttctgtg attcgcttgg ttgtcccagc tcttacagaa gagactcgtc gtgaccttgc
     3181 taaagaagtg aagaaggtcg gcgaaaatgc taaagtggct gtccgcaata tccgtcgcga
     3241 tgctatggac gaagctaaga aacaagaaaa agcaaaagaa atcactgaag acgaattgaa
     3301 gactcttgaa aaagacattc aaaaagtaac agacgatgct gttaaacaca tcgacgatat
     3361 gactgccaac aaagagaaag aacttttgga agtctaaaaa taaacagaaa aactcagttg
     3421 gcattgctgg ctgagtttta ttcgaaagaa ggaaatatga atacaaatct tgcaagtttt
     3481 atcgttggac tgatcatcga tgaaaacgac cgtttttact ttgtgcaaaa ggatggtcaa
     3541 acctatgctc ttgctaagga agaaggccaa catacagtag gggatacggt caaaggtttt
     3601 gcatacacgg atatgaagca aaaactccgc ctgacaagct tagaagtgac tgccactcag
     3661 gaccaatttg gttggggacg tgtcacagag gttcgtaagg acttgggtgt ctttgtggat
     3721 acaggccttc ctgacaagga aatcgttgtg tcactcgata ttctccctga gctcaaggaa
     3781 ctctggccta agaagggcga ccaactctac atccgtcttg aagtggataa gaaagaccgt
     3841 atctggggtc tcttggctta tcaagaagac ttccaacgtc ttgctcgtcc tgcctacaac
     3901 aacatgcaga accaaaactg gccagccatt gtttaccgtc tcaagctatc aggaactttt
     3961 gtttacctac cagaaaataa tatgcttggt tttattcatc ctagcgagcg ttacgcagag
     4021 ccacgtttgg ggcaagtatt agatgcgcgc gttattggtt tccgtgaagt ggaccgcact
     4081 ttgaacctct ccctcaaacc acgctccttt gaaatgttgg aaaacgatgc tcagatgatt
     4141 ttgacttatt tggaaagcaa tggcggtttc atgaccttaa atgacaagtc atctccagac
     4201 gacatcaagg caacctttgg catttctaaa ggtcagttca agaaagcttt aggtggtctt
     4261 atgaaggctg gtaaaatcaa gcaggaccag tttggtacag agttgattta gggaggctta
     4321 tgagaaaatc attttacact tggctcatga ccgagcgcaa tcctaaaagt aacaatccca
     4381 aagcaatttt ggcagacctc gcttttgaag aggcagcttt tccaaaacat acagatgatt
     4441 ttgatgaggt cagtcgcttt ttggaggagc atgccagttt ctcttttaac ctaggagatt
     4501 ttgacagcat ttggcaggaa tatctagaac actagcattt attcattggg tttgggctag
     4561 taatttctcc atccctctgc tataataaaa agaaataaaa ggattagaga ggttctttat
     4621 ttgaaggaac attcaataga cattcaactg agtcatccag atgacctgtt tcatcttttt
     4681 ggttccaatg aacgccatct tcgtttgatg gaagaagagc ttgatgttgt gattcatgct
     4741 cgtacggaga ttgtccaggt tttgggagaa gagtctgctt gcgaggaagc ccgtcaggtt
     4801 attcaagctc tcatggcctt ggtaaatcgt gggatgaccg ttggtacgcc agatgtagtg
     4861 acggctatta gtatggtcaa aaatgatgaa attgacaagt ttgtcgccct ttacgaagaa
     4921 gaaatcatca aggataatac tgggaagcct atccgcgtca aaaccttagg tcaaaaactt
     4981 tatgtggaca gtgtcaaaca gcatgatgtg acctttggaa ttgggccagc aggtacaggg
     5041 aagaccttcc ttgcagtgac cttggcagtg actgccctta aacgtgggca agtcaagcga
     5101 attatcctaa ctcgtccagc ggtggaagcg ggagagagtc ttggatttct tccgggtgat
     5161 cttaaggaga aggtggatcc ttaccttcgt cctgtttacg atgccttgta tcaaattctt
     5221 gggaaagacc aaacgactcg tctcatggag cgtgaaatta tcgaaattgc gccccttgcc
     5281 tatatgcgtg gccggacctt ggatgatgcc tttgtcattc tcgatgaggc gcaaaacacg
     5341 accatcatgc agatgaagat gttcttgacg cgtttaggct ttcattctaa gatgattgtc
     5401 aatggagata tcagtcagat tgacctgcca cgtaatgtca agtccggttt gattgatgct
     5461 caagagaaac tcaagaacat ccatcagatt gactttgttc atttttcagc caaggatgtg
     5521 gttcgccatc cagttgtcgc tcagattatc cgagcctatg aatattctac tgaagttgca
     5581 cacgactgat tttgaggaag ttcgcctgca aaagaatata cttttgagag aggaaaatcc
     5641 agttgtatag gctaaaggtt tgagacaacg attaggcacg atggaaagaa cttttatgtg
     5701 gctgatgacg atcagtgcat cttcctgtgt cataatcaca gggcacaaga aagtaggaat
     5761 ttgaaaagat gattgaccaa ctatctaagt attacagttg taggatacta actgaaaagg
     5821 atattccaag tattttatct ttatatgaaa gtaatcctct gtattttcag cattgtccac
     5881 cagagccaaa ttttgcaact gtaaaagagg acatgctttg tctacctgaa ggtaaagcta
     5941 aggctgataa gttttttgtt ggattttgga atggctctga ccttgtggct gttatggatt
     6001 ttgtctatgc atatcctgat gaggagactg tttttattgg tttgtttatg gttgatcaag
     6061 cctatcagag gaaagggatt ggtagtcata ttgtgacaga agcactagct tattttgcta
     6121 agaactttcg aaaggcacgt ttggcttatg ttaagggaaa tccgcaatct cagcattttt
     6181 gggaaaagca gggctttaaa tcaattggat gcgaggttaa gcaagaactc tatacggttg
     6241 ttatcgctga acagagccta gaagattaga aatggcatca agtaagaact atttggaatt
     6301 tgttttggaa caattatcag gattagatga tgtgacttac cgttccatga ttggggagta
     6361 tattctttac ttccgcggca agattattgg cggcatttat gacgatcgct ttttagttaa
     6421 acccgtgcaa gcagtcttag ataagattga ccaatcttct tttgagtttc catacaaagg
     6481 tgccaaagaa atgatttgag tggaagaact tgataataag atgtttctat aagacctgat
     6541 tttagctatg tataaccaac tgccaacgcc caaacctaaa aagaaaaagc aagggtgaac
     6601 gaagtaaaaa agaagtctgc taaggccctg tctttgcacg ggtaaaattt tatatataaa
     6661 aagaagctgg gactaaagag ctcagcttcc tttggtttat ataattgtca ttacaagacg
     6721 aagtggttgg gcgaaactct gttgacttta ttcaatttag agtttcttat gcacaattga
     6781 gtctggaacg aaagtctcca gttgcaaagt atacagtaca ataaaccaac gatgtaatag
     6841 ctgatgacac aaagcacagt gggtaggact tgcgaagtca cccttttctt ttcaaaattt
     6901 atactaaatc attgatatca gtgtagtcac gattaagtcc ttgagcaact ggtaggctag
     6961 tcaagtaacc ttgataagtg gtcacacctt gacgcaagcc ttcatcttca gagattgctt
     7021 gtgcgaatcc tttgccagcc aaagcttcga tataaggaag agtgacattg gttagggcga
     7081 tggttgaagt gcgggcaacc gcaccaggga tattggcaac ggcatagtgg agaacaccgt
     7141 gtttttcata gacgggttca tcgtgcgttg tcacacggtc agctgtttcg ataacgccac
     7201 cttggtcaac agcaacgtca acgatacaga gcctggacgc atttgtttga ccatctcatc
     7261 tgtcaccaat tccggtgctt ttgcaccagg gatgagaatg gctccaatca ccacatcagc
     7321 atctctcaca cttgcttcaa tgttgaatga attagatata atagtttgaa tttgacttcc
     7381 aaagacttct tctagaactg agagacgctt ggcactaata tctaaaatag tcacttgagc
     7441 accaagacca agggcgatgc gggcagcatg tgtaccgacg acaccatcac cgatgatagt
     7501 tacttttcct tttggaacac ctggtacacc accaagtaga acaccagagc caccagcttg
     7561 cttagtaagg aagtgagctc cgatttgaac agccatacga cctgcaacct cactcatagg
     7621 aacgaggagc ggtagttgtc cttgattgtc acgaacagtt tcataggcaa ttcctgttgt
     7681 ttttgctgct aacatagcat ctgctaattc tggagcagcg gccatgtgca agtaggtgaa
     7741 gagaagaaga tcgtcgcgca agtaaccgta ttcagaactt aaaggttctt ttactttcac
     7801 aaccaactct gctgcccaag cttcaccagc agtagcgaca atctcagctc cttgcttttg
     7861 atagtcagca tcagtaaagc cagaaccgag accagcattt gtttcgataa ggacacgatg
     7921 accacgacta actaagctat gaacacctgc aggtgtgagg gcgacacggt tttcgttatt
     7981 tttaatttct tttgggattc cgattaacat tgagataacc tacctttcaa ttgacggtct
     8041 tgttttggtt gtcacattcc agttcataaa tcaaaaatgt gacggtttca ttgtatatga
     8101 aaccgcttca aaaatcaaga aaaacttgtc atccaaattt ttttatgcta gactagtgaa
     8161 aatcaagctc taatggaggg aaaagtatgg aatcaatatt tgtgaaattt gcccagtatc
     8221 cgtctataga aacggagcgt ttattgctta gacctgtaac tttggatgat gcggaagcaa
     8281 tgtttgacta tgcctcggac aagggtaata cacgttacac ttttccaacc aatcaaagct
     8341 tggaagaaac caagaataac attgctcagt tctacttggc taatcccttg ggacgttggg
     8401 ggattgaatt aaaagataac ggcaagttta tcggaactat tgacttacac aagattgatc
     8461 ctgttcttaa gaaggcagct attggctaca ttatcaataa aaagtattgg aatcaaggat
     8521 taacgacaga agccaatcgt gctgtgattg agctagcttt tgagaagata gggatgaata
     8581 agttgactgc ccttcacgat aaggctaatc ccgcgtcagg aaaggtcatg gagaaatcag
     8641 gcatgcgttt ttcccatgca gaaccatatg cttgtatgga ccagcatgaa aaaggccgaa
     8701 tcgtgacaag agttcattat gtcttgacca aggaagacta ttttgcaaat aaataagcag
     8761 ttgaaaagaa atttttcgac tgttttttct tcctcttacg aataatctaa gagaggagaa
     8821 aatatggaag caattatcga gaaaatcaaa gagtataaaa tcatcgtcat ctgtactggt
     8881 ctgggcttgc ttgtaggagg atttttcctg ctaaagccag ctccacaaac atctgtcaaa
     8941 gagacgaatt tgcaggctga agttgcagct gtttccaagg actcatcgac cggaaaggaa
     9001 gtgaacaagg aagagaagga agaaccagtt gaacaagatc taatcacagt agatgtcaaa
     9061 ggtgctgtca aatcgccagg gatttatgac ttgcctgtag gtagtcgagt caatgatgct
     9121 gttcagaagg ctggtggctt gacagagcaa gcagacagca agtcgctcaa tctagctcag
     9181 aaagttagtg atgaggctct ggtttacgtt cctactaagg gagaagaagc agttagtcaa
     9241 cagactggtt cggggacagc ttcttcaaca agcaaggaaa agaaggtcaa tctcaacaag
     9301 gccagtctgg aagaactcaa gcaggtcaag ggactgggag gaaaacgagc tcaggacatt
     9361 attgaccatc gtgaggcaaa tggcaagttc aagtcagtag acgagctcaa gaaggtctct
     9421 ggcattggtg ccaagaccat agaaaaactt aaagactatg ttacagtgga ttaagaattt
     9481 ctctattccc ctaatttacc tgagttttct attactatgg ctttactacg ccattttctc
     9541 agtatcctat tttgctttgt tgggttttgt ttttctgcta gtctgcctct ttatccaatt
     9601 tccttggaaa tcagcaggta aagttctagt gatttgtgga gtctttggct tctggtttct
     9661 gtttcaaact tggcaacaga gtcaagtgag tcaaaatttg gtggattctg ttgaaagggt
     9721 acggatttta ccagacacta ttaaggttaa cggtgacagt ctgtcctttc gtggtaagtc
     9781 tgatggtcgt gctttccaag tctattataa actccagtcc gaggaggaga aagaagcctt
     9841 tcaagcttta actgaccttc atgagatagg actagaaggg aagctttcgg agccagaagg
     9901 gcagagaaat tttggtggct ttgactacca aggctatctg aagactcagg gaatttacca
     9961 gacactcaat attaaaagaa tccagtcact ccaaaaggtt ggcagttggg atataggtga
    10021 aaacctgtcc agtttacgtc gaaaggctgt ggtttggatt aagatgcact tcccagaccc
    10081 tatgcgcaat tacatgacag gactcttgct aggacatctg gacaccgatt ttgaggagat
    10141 gaatgagctt tattccagtt taggaattat tcaccttttt gccttgtcag gtatgcaggt
    10201 agggtttttc atggacggat ttaagaaact acttttacga ttgggcttga cacaagaaaa
    10261 gttgaagtgg ctgacttatc ccttttccct tatctatgcg ggactaactg gattttcagc
    10321 atcggttatt cgcagtctct tgcaaaagct actggctcaa catggggtta agggcttgga
    10381 taattttgcc ttgacggtgc ttgtcctctt tattgtcatg ccaaactttt tcttgacagc
    10441 aggaggagtc ttgtcctgtg cttatgcttt tatcctgacc atgaccagca aagaagggga
    10501 ggggctcaag gctgttacta gtgaaagtct agtcatctcc ttgggcatat tgcccattct
    10561 atccttctat tttgcggaat ttcaaccttg gtctatcctt ttgacctttg tcttttcctt
    10621 tctttttgac ttggtcttct taccgctctt gtctatctta tttgtccttt cctttctcta
    10681 tccagtcatt cagctgaact ttatctttga atggttagag ggcattattc gcttggtctc
    10741 gcaggtggca agtagaccgc ttgtctttgg acaacccaat gaatggcttt taatcctatt
    10801 gttaatttct ttggctttgg tctatgattt gaggaaaaac attaaaaagc taacggtatt
    10861 gtgcttattg attacagggc tctttctcct gaccaagcat ccactggaaa atgaaatcac
    10921 catgctggat gtggggcaag gagaaagtat tttcctacgg gatgtaactg ggaaaaccat
    10981 tctcatagat gtaggtggta aggcagaatc ttataagaaa atcaaaaaat ggcaagaaaa
    11041 gatgacgacc agcaatgccc agcgaagctt gataccctat ctcaaaagtc gaggagtagc
    11101 taagattgac cagctaattt tgactaacac ggacaaggag catgttggag atttgtcaga
    11161 gatgaccaag gctttccatg taggggagat tctagtatca aaagacagtc tgaaacagaa
    11221 ggaatttgtg gcagaactac aggcgactca aacaaaggtg cgtagtatga tagtagggga
    11281 gaacttaccc atttttggaa gtcagttaga agttctatct ccaaggaaaa tgggagatgg
    11341 aggacacgat gataccctag ttctgtatgg gaaattcttg gataagcaat ttctcttcac
    11401 gggaaatttg gaggagaaag gagagaagga cttgctgaag cactatccag acttgaaagt
    11461 aaatgttttg aaagctagcc aacatggcaa taaaaaatca tcaagtccag cctttctaga
    11521 aaaactcaaa ccagagctta ctcttatctc agttggaaag agcaatcgaa tgaaactccc
    11581 ccatcaggaa acattgacac gactggaagg tatcaatagc aaagtttatc gaactgacca
    11641 gcaaggagct atacgtttta aggggttgga tagttggaaa atcgaaagtg ttcgatagga
    11701 aggataaatg ttgtagatta gtgaaataaa ctaaaaattt gttgcataat aatgataaaa
    11761 acggcataat gaaaacgtat tcaatattga ggatataaaa tcattaaaaa tcagcaaaag
    11821 ttgttttagt tagttagttt ataatctatt ggtcttcttc agtccagtgt atctgctgtg
    11881 acagtcacta aaagttacaa gtatgattgg aatacggttt tggaatatag taccaactat
    11941 cacgaccatc agtatgcttg gattccggaa tggtctcgtt attacagcta ttctgagtat
    12001 aaagttggcg gaggctggaa ctacgctcgt tatgaggtca taaactacta tactggaggt
    12061 tattaatcct taaagagtga gaaaaggagg gctggatatg ttaaatctta ctcatgttac
    12121 cttaaaaacg cgacaagtca tcttgcaaga tgcggatttt acctttaaaa agggtaggat
    12181 ttatggcctt cttgctatca atggctcggg aaagacgaca ctattccgag ctatgagcaa
    12241 gttgcttccc cttagtagtg gacacatcgc agttcctcct tctttgtttt attatgagag
    12301 cgttgaatgg ctggatggaa acttaagtgg gatggactac cttcgtctca taaaaaacat
    12361 ctggaagtca gacctaaact tgagagatga aatcgcctac tgggaaatgg ctgactatat
    12421 cagtcttccc atccgcaagt attccttagg gatgaagcaa cgcttggtga ttgctatgta
    12481 ttttctcagt caggccaaat gctggctcat ggatgagatt acaaatggct tagacgagta
    12541 ttatcgacag aagttttttg ataggctagc acaaatcgat agacaagaac agctggttct
    12601 tttaagttcc cactataagg aagagttggt tgatatctgc gatagagtag taaccattca
    12661 tcaggggcag atagaagagg tttagtttat gaaagatgtt agtctatttt tattgaaaaa
    12721 agttttcaaa agtcgtttaa actggattat cttagcttta tttgtatctg tactcggtgt
    12781 taccttttat ttaaatagtc agactgcaaa ctcacacagc ttggagagca ggttggaaag
    12841 tcgcattgca gccaacgaga gggctatcaa tgaaaatgaa gagaaactct cccaaatgtc
    12901 tgataccagc tcggaggaat accagtttgc taaaaataat ttagacgtgc aaaaaaatct
    12961 tttgacgcga aagacagaaa ttctaacttt actaaaagaa gggcgctgga aagaagccta
    13021 ctatctgcag tggaaagatg aagagaagaa ttatgaattt gtatcaaatg acccgactgc
    13081 tagctctggc ttaaaaatgg gggttgaccg cgaacggaag atttaccaag ccctgtatcc
    13141 cttgaacata aaagcacata ctttggagtt tccgacccac gggattgatc agattgtctg
    13201 gattttagag gttatcatcc caagcttgtt tgtggttgcg attattttta tgctaacaca
    13261 actatttgca gaaagatatc aaaatcatct ggacacagct cacttatatc ctgtttcaaa
    13321 agtgacattt gcaatatcct ctcttggagt tggagtggga tatgtaactg tgctgtttat
    13381 cggaatctgt ggcttttctt ttctagtggg aagtctgata agtggttttg gacagttaga
    13441 ttatccctac ccaatttata gcttagtgaa tcaagaagta actattggga aaatacaaga
    13501 tgtattattt cctggcttgc tcttagcttt cttagccttt atcgtcattg tggaagttgt
    13561 gtacttgatt gcttactttt tcaagcaaaa aatgcctgtc ctctttcttt cactcattgg
    13621 gattgttggc ttattgtttg gcatccaaac aattcagcct cttcaaagga ttgcacatct
    13681 gattcccttt acttacttgc gttcagtgga gattttatct ggaagattac ctaagcagat
    13741 tgataatgtc gatctaaatt ggagcatggg aatggtctta cttccttgcc tgattatctt
    13801 tttgctattg ggaattctat ttattgaaag atggggaagt tcacagaaaa aaagaatttt
    13861 ttaatagatt ctagctttcc tataggtagg gaaaataagt aaaaactaac atagagaggg
    13921 aatcaacttg attctctctt tttgattcga aaaccaaacc aaaatacaaa cacaaacttt
    13981 tcaaaaaata actttttatc ttgacaagag ctagaaaact tggtatcata taaaagttga
    14041 gaaaagcaga agtgagagct tctcgccttg tgacattaag ttgcctggcc ctacggatga
    14101 aaagtttcga agaaacgcta tcataacgtg cgggcttgta tatttacgag tccgctattg
    14161 tttttctcta ataaaacaaa agaggtgaaa accatagcaa agcaagactt attcatcaat
    14221 gatgagattc gtgtacgtga agttcgcttg attggtcttg aaggagaaca gctaggcatc
    14281 aagccactca gtgaagcgca agctttggct gataacgcta atgttgacct agtattgatt
    14341 caaccccaag ccaaaccgcc tgttgcaaaa attatggact acggtaagtt caaatttgag
    14401 taccagaaga agcaaaaaga acaacgtaaa aaacaaagcg ttgttactgt gaaagaagtt
    14461 cgtctaagtc caactattga caagggtgac tttgatacaa aacttcgtaa tgcacgtaag
    14521 ttccttgaaa aaggaaataa agttaaggta tctattcgct ttaagggtcg tatgattacc
    14581 cataaagaga ttggtgcaaa agttttagcc gagtttgctg aagcaactca agatattgcc
    14641 atcatcgaac aacgtgctaa aatggatgga cgtcaaatgt tcatgcaatt ggcgccagcg
    14701 actgacaaaa aataattgtc agaaagttaa ataaaggaga aaaaattatg ccaaaacaaa
    14761 aaacacaccg cgcatcagct aaacgtttca aacgtacagg ttctggtgga cttaaacgtt
    14821 tccgtgctta cacttctcac cgtttccacg gaaaaactaa gaaacaacgt cgtcatcttc
    14881 gtaaagcatc tatggtgcat tcaggagatt acaaacgtat caaagcaatg cttactcgct
    14941 tgaaataata gcttgactgt aagtaaacaa ttctaggaaa tatttggagg aaataaaaca
    15001 tggcacgtgt taaaggtggc gttgtatcac gcaaacgtcg taaacgtatt cttaaattag
    15061 caaaaggtta ctatggagct aaacacatct tgttccgtac tgcaaaagaa caagtaatga
    15121 actcttacta ctatgcatac cgtgaccgtc gtcagaaaaa acgtgacttc cgcaaattgt
    15181 ggatcactcg tatcaatgcg gcagctcgta tgaacggact ttcatactca caattgatgc
    15241 atggtttgaa attggctgag atcgaagtta accgtaaaat gcttgctgac ttggctgtta
    15301 acgatgcagt agctttcaca gctcttgcag atgcagctaa agcaaaactt ggtaaataac
    15361 aactgatgag actggaacag gattgtccag tctttttaaa aataaaggag aaaaatatgg
    15421 cttcaaaaat gctacacact tgcttacgag tagaaaatct tgaaaaatca atcgcatttt
    15481 atcaagatgc ttttggtttt aaagaattgc gtcgcagaga ttttccagac catgccttca
    15541 cgattgtcta tctaggtctt gagggtgatg actatgagtt ggagttgact tataactacg
    15601 atcacggtcc gtatgtggtt ggtgatgggt ttgcccatat cgccctcagt acacctgatc
    15661 ttgaggcact tcatcaagaa cacagtgcaa aaggctatga agtgactgag ccaaatggtc
    15721 taccaggaac tacaccaaac tattactttg tcaaagaccc tgatggatat aaggtcgaag
    15781 tcattcgtga aaaataattt cgtgcaagtt aagtagaata ttcgtttttt acttgacttt
    15841 ttttagctga aagagtatac taataaaaat tcaaccttta aggggagtcc agagagactc
    15901 acaaggtgtc agataaaaga atagtgcaat tttctagagg agactttttg agtgtgctct
    15961 cttgtgttgt acgattttaa ctgaggcctt gcactagcaa ggtcttttct ttatctggtc
    16021 cccttaaaat ttaaggagga aaagttatga atcccacatg taagaagcgt ttgggtgtca
    16081 ttcggttgga aaccatgaag gtggttgcac aagaggaaat cgcgccagca atctttgaat
    16141 tagtcctaga aggagaaatg gttgaagcca tgcgagcagg ccaatttctt catctgcgtg
    16201 taccagacga tgcccatctt ttacgtcgtc ctatttcaat ttcgtctatt gacaaggcaa
    16261 acaagcagtg tcacctcatt tatcggattg agggagctgg gactgcaatt ttttcaacct
    16321 taagtcaggg agacactctt gatgtgatgg ggcctcaggg aaatggtttt gacttgtctg
    16381 accttgatga gcagaatcag gttctccttg ttggtggtgg gattggtgtt ccacccttgc
    16441 ttgaggtggc caaggaattg catgaacgtg gagtgaaagt agtgacagtc ctcggttttg
    16501 ctaataagga tgctgttatt ttgaaaacgg aattggctca gtatggtcag gtctttgtaa
    16561 cgacagatga tggttcttat ggcatcaagg gaaatgtttc cgttgttatc aatgatttag
    16621 atagtcagtt tgatgctgtt tactcgtgtg gggctccagg aatgatgaag tatatcaatc
    16681 aaacctttga tgatcaccca agagcctatt tatctctgga atctcgtatg gcttgtggga
    16741 tgggagcttg ctatgcctgt gttctaaaag taccagaaag cgagacggtc aaccaacgcg
    16801 tctgtgaaga tggtcctgtt ttccgcacag gaacagttgt attataagga gaaaattatg
    16861 actacaaatc gattacaagt gtctctacct ggtttggatt tgaaaaatcc gattattcca
    16921 gcatcaggtt gttttggctt tggacaagag tatgccaagt actatgattt aaacctttta
    16981 ggttctatta tgatcaaggc gacaaccctt gaaccacgtt ttgggaaccc aactccaaga
    17041 gtagcagaga cgcctgctgg tatgctcaat gcaattggct tgcaaaatcc tggtttagag
    17101 gttgttttgg ctgaaaagct accttggctg gaaagagaat atccaaatct tcctattatt
    17161 gccaatgtag ctggtttttc aaaacaagag tatgcagctg tttctcatgg gatttccaag
    17221 gcaactaatg taaaagctat cgagctcaat atttcttgtc ccaatgttga ccactgtaat
    17281 catggacttt tgattggtca agatccagat ttggcttatg atgtggtgaa agcagctgtg
    17341 gaagcctcag aagtgccagt ttatgtcaaa ttaaccccga gtgtgaccga tatcgttact
    17401 gtcgcaaaag ctgcagaaga tgcgggagca agtggcttga ccatgatcaa tactctggtt
    17461 ggaatgcgct ttgacctcaa aaccagaaaa ccaatcttgg ccaatggaac aggtggaatg
    17521 tcaggtccag cagtctttcc agtagccctc aaactcatcc gccaagtagc ccaaacaaca
    17581 gacctgccta tcattggaat ggggggagtg gattcggctg aagctgccct agaaatgtat
    17641 ctggctgggg catctgctat cggagttgga acagctaact ttaccaatcc ttatgcctgc
    17701 cctgacatca tcgaaaattt accaaaagtc atggataaat acggtattag cagtctggaa
    17761 gaactccgtc aggaagtaaa agagtctctg aggtaaactg caatcaatct gttcttgatt
    17821 ttttattagt ttgtaatatg aatttaggag aattttggta caataaaata aataagaaca
    17881 gaggaagaag gttaatgaag aaagtaagat ttattttttt agctctgcta tttttcttag
    17941 ctagtccaga gggtgcaatg gctagtgatg gtacttggca aggaaaacag tatctgaaag
    18001 aagatggcag tcaagcagcg aatgagtggg tttttgatac tcattatcaa tcttggttct
    18061 atataaaagc agatgctaac tatgctgaaa atgaatggct aaagcaaggt gacgactatt
    18121 tttacctcaa atctggtggc tatatggcca aatcagaatg ggtagaagac aagggagcct
    18181 tttattatct tgaccaagat ggaaagatga aaagaaatgc ttgggtagga acttcctatg
    18241 ttggtgcaac aggtgccaaa gtaatagaag actgggtcta tgattctcaa tacgatgctt
    18301 ggttttatat caaagcagat ggacagcacg cagagaaaga atggctccaa attaaaggga
    18361 aggactatta tttcaaatcc ggtggttatc tactaacaag tcagtggatt aatcaagctt
    18421 atgtgaatgc tagtggtgcc aaagtacagc aaggttggct ttttgacaaa caataccaat
    18481 cttggtttta cataaaagaa aatggaaact atgctgataa agaatggatt ttcgagaatg
    18541 gtcactatta ttatctaaaa tctggtggct acatggcagc caatgaatgg atttgggata
    18601 aggaatcttg gttttatctc aaatttgatg ggaaaatagc tgaaaaagaa tgggtctacg
    18661 attctcatag tcaagcctgg tactacttca aatccggtgg ttacatgaca gccaatgaat
    18721 ggatttggga taaggaatct tggttttacc tcaagtctga tggcaaaatg gctgaaaaag
    18781 aatgggtcta cgattctcat agtcaagcct ggtactactt caaatctggt ggttacatgg
    18841 cgaaaaatga gacagtagat ggttatcagc ttggaagcga tggtaaatgg cttggaggaa
    18901 aagctacaaa tgaaaatgct gcttactatc aagtagtgcc tgttacagcc aatgtttatg
    18961 attcagatgg tgaaaagctt tcctatatat cgcaaggtag tgtcgtatgg ctagataagg
    19021 atagaaaaag tgatgacaag cgcttggcta ttactatttc tggtttgtca ggctatatga
    19081 aaacagaaga tttacaagcg ctagatgcta gtaaggactt tatcccttat tatgagagtg
    19141 atggccaccg tttttatcac tatgtggctc agaatgctag tatcccagta gcttctcatc
    19201 tttctgatat ggaagtaggc aagaaatatt attcggcaga tggcctgcat tttgatggtt
    19261 ttaagcttga gaatcccttc cttttcaaag atttaacaga ggctacaaac tacagtgctg
    19321 aagaattgga taaggtattt agtttgctaa acattaacaa tagccttttg gagaacaagg
    19381 gcgctacttt taaggaagcc gaagaacatt accatatcaa tgctctttat ctccttgccc
    19441 atagtgccct agaaagtaac tggggaagaa gtaaaattgc caaagataag aataatttct
    19501 ttggcattac agcctatgat acgacccctt acctttctgc taagacattt gatgatgtgg
    19561 ataagggaat tttaggtgca accaagtgga ttaaggaaaa ttatatcgat aggggaagaa
    19621 ctttccttgg aaacaaggct tctggtatga atgtggaata tgcttcagac ccttattggg
    19681 gcgaaaaaat tgctagtgtg atgatgaaaa tcaatgagaa gctaggtggc aaagattagt
    19741 actataagtg aatatgattt gagtgaatag taagttaaaa atcctgattt caagtaaaat
    19801 caggattttt tcatggatgc aatttttttg gagtctggtg tgacgcggag ggtcttttgt
    19861 cctgtgtaag tgacaaagcc gggttttcca ccagttggtt tattgagttt tttgacttca
    19921 atcatatcta cctgcaccag attcgacagg cgcccttgag agaagtaggc agctaactct
    19981 gctgcgtctg tcttgactgc atcagatggg tcaagatttc ctgagatgac aacatggctt
    20041 ccaggaatgt ccttagcatg gaaccaaagt tcctccttgc gggccatttt aaaggtcaat
    20101 tcctcatttt gaagattgtt tcgtccgaca tagatgatgg ttttgccatc gcttgctaga
    20161 tattgttcta gttttttgcg tttctggatt ttctcccgtt gtcttctgcg gataaaacct
    20221 gtttgaatca attcttcacg gatttcagcg atttcttcca gtccagcttg gttgaggacg
    20281 gtttctacac tttccagata gagaatagtg gctttggttt cttcaatcaa atcagtcaag
    20341 tatttgacag cttctttgag tttctgatac cgtttaaaat agcgttgggc attctggttg
    20401 ggagtcagag ccttatcaag cgcaatcatg ataggttggt tggtatagta gttgtctagg
    20461 ataacctggt cttggtcgtt aggcacttgg tggaggaagg ttgtcagcaa ttctcctttt
    20521 tgacgaaatt cttcagcgtt gtctgtcgcc agtaactctt tttcctgttt tttgagtttg
    20581 tgtcggtttt tctgaagttc attttcaaca cgacgaatca gttcactggc ctgctgtttg
    20641 acgcggtcgc gctcagcctt atccttatag taggtgtcca acaaatcaga aagatttgca
    20701 agaggctctc ccacctgatt tgcaaaagga actggactga aggaagtctc agtcaagcat
    20761 ggcttggttt cttgattgaa aaaatttcgg aaagcggaaa gtttttcact aaccagtatc
    20821 ctttccaatt catttgccgt atcgcgtccc agaccttgaa agaggctttg aagatttttt
    20881 gctgttagtt cttgggtttg caggatttca aagagctttt catccttgat agtaaaagga
    20941 ttgagagatt ttgtacttgg cggagcgata taggtcgatc ctggaagtaa ggtgcggtag
    21001 ctattttgtg aaaagccgac gtgtttgata acttcgagga ttttatgact gcttttatcg
    21061 accagtagaa tattactgtg tttccccata atttcgataa tcaaggtagc ctggatatgg
    21121 tctccaatct cgtttttatt ggaaactgta atttccacaa tacggtcatt ttccacttgc
    21181 tcaatcgact caatcagggc cccctgcaaa tactttctca aaaccatgat aaaggtagaa
    21241 ggttgggctg gattttcaaa agtcgtttgg gtcagctgaa tgcgtccaaa aactggatgg
    21301 gcagaaagga gcaggcgatg gctttggcga ttgctgcgga tttgcaagac caactcttgt
    21361 tcaaaaggct gattgatttt ctggatgcga ccattcacta attcgcttcg caattcctca
    21421 actatgtggt gtaaaaaaaa tccgtcaaat gacatcgttc tctccttgtg attgtattcc
    21481 atagtattat atcaaaaagg tagaataaaa tcatggaaat gtggtataat aaagccaagt
    21541 aaagagaaac gagaagcaca tgtatattga aatggtagat gaaactggtc aagtttcaaa
    21601 agaaatgttg caacaaaccc aagaaatttt ggaatttgca gcccaaaaat taggaaaaga
    21661 agacaaggag atggcagtca cttttgtgac caatgagcgt agtcatgaac ttaatctggg
    21721 gtaccgtgac accgaccgtc cgacagatgt catcagcctt gagtataaac cagaattgga
    21781 aattgccttt gacgaagagg atttgcttga aaatccagaa ttggcagaga tgatgtctga
    21841 gtttgatgcc tatattgggg aattgttcat ctctatcgat aaggctcatg agcaggccga
    21901 agaatatggt cacagctttg agcgtgagat gggcttcttg gcagtacacg gctttttaca
    21961 tattaacggc tatgatcact atactccgga agaagaagcg gagatgttcg gtttacaaga
    22021 agaaattttg acagcctatg gactcacaag acaataaacg aaaatggaaa aatcgtgacc
    22081 tgatatccag tttagaattt gccatcacag ggatttttac tgctatcaag gaagaacgca
    22141 atatgcgaaa acatgcagtg acggctctag tggtcatcct tgcaggtttt ggttttcagg
    22201 tgtcacgaat cgaatggctc tttctcctat tgagcatttt cttggtggta gcctttgaaa
    22261 ttatcaattc tgctatcgaa aatgtggtgg atttggccag tcactatcac ttttccatgc
    22321 tggctaaaaa tgccaaggat atggcggctg gcgcggtatt agtggtttct ctttttgcag
    22381 ccttaacagg cgcattgatt tttctcccac gaatctggga tttattattt taaacagtaa
    22441 gaggaaatta tgacttttaa atcaggcttt gtagccattt taggacgtcc caatgttggg
    22501 aagtcaacct ttttaaatca cgttatgggg caaaagattg ccatcatgag tgacaaggcg
    22561 cagacaacgc gcaataaaat catgggaatt tacacgactg ataaggagca aattgtcttt
    22621 atcgacacac cagggattca caaacctaaa acagctctcg gagatttcat ggttgagtct
    22681 gcctacagta cccttcgcga agtggacact gttcttttca tggtgcctgc tgatgaagcg
    22741 cgtggtaagg gggacgatat gattatcgag cgtctcaagg ctgccaaggt tcctgtgatt
    22801 ttggtggtga ataaaatcga taaggtccat ccagaccagc tcttgtctca gattgatgac
    22861 ttccgtaatc aaatggactt taaggaaatt gttccaatct cagcccttca gggaaataac
    22921 gtgtctcgtc tagtggatat tttgagtgaa aatctggatg aaggtttcca atatttcccg
    22981 tctgatcaaa tcacagacca tccagaccgt ttcttagttt cagaaatggt tcgcgagaaa
    23041 gtcttgcacc taactcgtga agagattccg cattctgtag cagtagttgt tgactctatg
    23101 aaacgagacg aagagacaga caaggttcac atccgtgcaa ccatcatggt cgagcgcgat
    23161 agccaaaaag ggattatcat cggtaaaggt ggcgctatgc ttaagaaaat cggtagcatg
    23221 gcccgtcgtg atatcgaact catgctagga gacaaggtct tcctagaaac ctgggtcaag
    23281 gtcaagaaaa actggcgcga taaaaagcta gatttggctg actttggcta taatgaaaga
    23341 gaatactaag tagaggtggg ctcatgcctg cttcttgttt ttacagaagg aggacttatg
    23401 cctgaattac ctgaggttga aaccgtttgt cgttgcttag aaaaattgat tataggaaag
    23461 aagatttcga gtatagaaat tcgctacccc aagatgatta agacggattt ggaagagttt
    23521 caaagggaat tgcctagtca gattatcgag tcaatgggac gtcgtggaaa atatttgctt
    23581 ttttatctga cagacaaggt tttgatttcc catttgcgga tggagggcaa gtatttttac
    23641 tatccagacc aaggacctga acgcaagcat gcccatgttt tctttcattt tgaagatggt
    23701 ggcacgcttg tttatgagga tgttcgcaag tttggaacca tggaactctt ggtgcctgac
    23761 cttttagacg cctactttat ttctaaaaaa ttaggtcctg aaccaagcga acaagacttt
    23821 gatttacagg tctttcaatc tgcccttgcc aagtccaaaa agcctatcaa atcccatctc
    23881 ctagaccaga ccttggtagc tggacttggc aatatctatg tggatgaggt tctctggcga
    23941 gctcaggttc atccagctag atcttcccag actttgacag cagaagaagc gacagctatt
    24001 catgaccaaa ccattgctgt tttgagccag gctgttgaaa aaggcggttc caccattcgg
    24061 acctatacca atgcctttgg ggaagatgga agcatgcagg attttcatca ggtctatgat
    24121 aagactggtc aaggatgtgt acgctgtggt accatcattg agaaaattca actaggtgga
    24181 cgtggaaccc acttttgtcc aaactgtcaa aggagggact gatgggaaaa atcatcggaa
    24241 tcactggggg aattgcctct ggtaagtcaa ctgtgacaaa ttttctaaga cagcaaggct
    24301 ttcaagtagt ggatgccgac gcagtcgtcc accaactaca gaaacctggt ggtcgtctgt
    24361 ttgaggctct agtacagcac ttttggcaag aaatcattct tgaaaacgga gaactcaatc
    24421 gccctctcct agctagtctc atcttttcaa atcctgatga acgagaatgg tctaagcaaa
    24481 ttcaagggga gattatccgt gaggaactgg ctactttgag agaacagttg gctcagacag
    24541 aagagatttt cttcatggat attcccctac tttttgagca ggactacagc gattggtttg
    24601 ctgagacttg gttggtctat gtggaccgag atgcccaagt agaacgctta atgaaaaggg
    24661 accagttgtc caaagatgaa gctgagtctc gtctggcagc ccagtggcct ttagaaaaaa
    24721 agaaagattt ggccagccag gttcttgata ataatggcaa tcagaaccag cttcttaatc
    24781 aagtgcatat ccttcttgag ggaggtaggc aagatgacag agattaactg gaaggataat
    24841 ctgcgcattg cctggtttgg taattttctg acaggagcca gtatttcttt ggttgtacct
    24901 tttatgccta tcttcgtgga aaatctaggt gtagggagtg agcaagtcgc tttttatgca
    24961 ggcttagcaa tttctgtctc tgctatttcc gcggcgctct tttctcctat ttggggtatt
    25021 cttgctgaca aatacggccg aaaacccatg atgattcggg caggtcttgc tatgactatc
    25081 actatgggag gcttggcctt tgtcccaaat atctattggt taatctttct tcgtttacta
    25141 aacggtgtat ttgcaggttt tgttcctaat gcaacggcac tgatagccag tcaggttcca
    25201 aaggagaaat caggctctgc cttaggtact ttgtctacag gcgtagttgc aggtactcta
    25261 actggtccct ttattggtgg ctttatcgca gaattatttg gcattcgtac agttttctta
    25321 ctggttggta gttttctatt tttagctgct attttgacta tttgctttat caaggaagat
    25381 tttcaaccag tagccaagga aaaggctatt ccaacaaagg aattatttac ctcggttaaa
    25441 tatccctatc ttttgctcaa tctcttttta accagttttg tcatccaatt ttcagctcaa
    25501 tcgattggcc ctattttggc tctttatgta cgcgatttag ggcagacaga gaatcttctt
    25561 tttgtctctg gtttgattgt gtccagtatg ggcttttcca gcatgatgag tgcaggagtc
    25621 atgggcaagc taggtgacaa ggtgggcaat catcgtctct tggttgtcgc ccagttttat
    25681 tcagtcatca tctatctcct ctgtgccaat gcctctagcc cccttcaact aggactctat
    25741 cgtttcctct ttggattggg aaccggtgcc ttgattcccg gggttaatgc cctactcagc
    25801 aaaatgactc ccaaagccgg catttcgagg gtctttgcct tcaatcaggt attcttttat
    25861 ctgggaggtg ttgttggtcc catggcaggt tctgcagtag caggtcaatt tggctaccat
    25921 gctgtctttt atgcgacgag cctttgtgtt gcctttagtt gtctctttaa cctgattcaa
    25981 tttcgaacat tattaaaagt aaaggaaatc tagtgcgagt aaaaattaat ctcaaatgct
    26041 cctcttgtgg cagtatcaat tacctaacca gtaaaaattc aaaaacccat ccagacaaga
    26101 ttgaggtttt aaagtattgt cccaaggaaa gaaaagtaac cctacatctt gaatctaagt
    26161 agattttatg gtaaaataat agggatttta aggagtttga tatgtataac ctattattaa
    26221 ccattttatt agtattatct gttgtgattg tgattgcaat tttcatgcaa ccaaccaaaa
    26281 accaatccag caatgtattt gatgccagtt caggtgattt gtttgaacgt agtaaagctc
    26341 gcggttttga agctgtaatg cagcgtttga cagggatttt agtctttttc tggctagcca
    26401 ttgccttagc attgacggta ttatcaagta gataagaaaa taatgggcag gactaggtct
    26461 ttgcctcttt ttatttttaa aggatgtttg agaaggtttt acagtaaaag aaaattaaaa
    26521 aatctagaaa gaaaatatga aagatagaat aaaagaatat ttacaagaca agggaaaggt
    26581 gactgttaat gatttggctc aggctttggg aaaagacagt tccaaggatt ttcgtgagtt
    26641 gattaaaacc ttgtccttaa tggaaagaaa gcaccaaatt cgttttgaag aagatggtag
    26701 tctgacatta gaaattaaga aaaaacatga gattaccctc aaggggattt ttcatgccca
    26761 taaaaatggc tttggctttg ttagtctgga aggcgaggag gacgaccttt ttgtagggaa
    26821 aaatgatgtc aactatgcta ttgatggtga taccgtcgag gtagtgatta agaaagtcgc
    26881 tgaccgcaat aagggaacag cagcagaagc caaaattatt gatatcctag aacacagttt
    26941 gacaacagtt gtcgggcaaa tcgttctgga tcaggaaaaa cctaagtatg ctggctatat
    27001 tcgttcaaaa aatcagaaaa tcagtcaacc gatttatgtt aagaaaccag ccctaaaatt
    27061 agaaggaaca gaagttctca aagtctttat cgataaatac ccaagcaaga aacatgattt
    27121 ctttgtcgcg agtgttctcg atgtagtggg acactcaacg gatgtcggaa ttgatgttct
    27181 tgaggtcttg gaatcaatgg acattgtatc cgagtttcca gaagctgttg ttaaggaagc
    27241 agaaagtgtg cctgatgctc cgtctcaaaa ggatatggaa ggtcgtctgg atctaagaga
    27301 tgaaattacc tttaccattg acggtgcgga tgccaaggac ttggacgatg cagtgcatat
    27361 caaggctctg aaaaatggca atctggagct tggggttcac atcgcagatg tttcttatta
    27421 tgtgaccgag gggtctgccc ttgacaagga agcccttaac cgtgcgactt ctgtttacgt
    27481 gacagaccga gtggtgccaa tgcttccaga acgactatca aatggcatct gctctctcaa
    27541 tccccaagtt gaccgcctga cccagtctgc tattatggag attgataaac atggtcgtgt
    27601 ggtcaactat accattacac aaacagttat caagaccagt tttcgtatga cctatagcga
    27661 tgtcaatgat atcctagctg gcgatgaaga aaagagaaaa gaatatcata aaattgtatc
    27721 aagtatcgaa ctcatggcca agcttcatga aactttagaa aacatgcgtg tgaaacgtgg
    27781 agctctcaat tttgatacca atgaagcgaa gattttagtg gataaacaag gtaagcctgt
    27841 tgatatcgtt cttcggcagc gtggtattgc cgagcggatg attgagtctt ttatgttgat
    27901 ggctaatgaa acagttgccg aacatttcag caagttggat ttgcctttta tctatcgaat
    27961 tcacgaggag cctaaggctg aaaaggttca gaagtttatt gattatgctt cgagttttgg
    28021 cttgcgcatt tatggaactg ccagtgagat tagtcaggag gcacttcaag acatcatgcg
    28081 tgctgttgag ggagaacctt atgcagatgt attgtccatg atgcttcttc gctctatgca
    28141 gcaggctcgt tattcggagc acaatcacgg ccactatgga ctagctgctg actattatac
    28201 tcactttacc agtccaattc gtcgttatcc agaccttctt gttcaccgta tgattcggga
    28261 ttacggccgt tctaaggaaa tagcagagca ttttgaacaa gtgattccag agattgcgac
    28321 ccagtcttcc aaccgtgaac gtcgtgccat agaagctgag cgtgaagtcg aagccatgaa
    28381 aaaggctgag tatatggaag aatacgtggg tgaagagtat gatgcagttg tatcaagtat
    28441 tgtcaaattc ggtctctttg tcgaattgcc aaacacagtt gaaggcttga ttcacatcac
    28501 taatctacct gaattttatc atttcaatga gcgtgatttg actcttcgtg gagaaaaatc
    28561 aggtatcact ttccgagtgg gtcagcagat ccgtatccgt gttgaaagag cggataaaat
    28621 gactggagag attgattttt cattcgtacc tagtgagttt gatgtgattg aaaaaggctt
    28681 gaaacagtct agtcatagtg gcagagggcg tggttcaaat cgtcgttcgg ataagaagga
    28741 agacaagaga aaatcaggac gctcaaatga taagcgtaag cattcacaaa aagacaagaa
    28801 gaaaaaagga aagaaacctt tttacaagga agtagctaag aaaggagcca agcatggcaa
    28861 agggcgaggg aaaggtcgtc gcacaaaata aaaaggcacg ccacgactat acaatcgtag
    28921 atacgctaga ggcagggatg gtcctgactg gaactgaaat caagagtgta cgagctgctc
    28981 gaattaatct caaggatggc tttgctcaag tgaaaaatgg agaagtttgg ctgagcaatg
    29041 ttcatatcgc gccttacgaa gagggcaata tctggaacca ggaaccagaa cgtcgtcgta
    29101 aactcctgct ccataaaaag caaattcaaa aattggaaca agagaccaaa gggacaggaa
    29161 tgaccttagt tccccttaag gtctatataa aagatggcta cgctaagctt cttttaggac
    29221 ttgccaaagg gaagcatgac tatgacaaac gggagtctat caaacgtcgt gagcaaaatc
    29281 gagatatcgc gcgtgtgatg aaagctgtta atcagcgata aaaagaggaa ttgaaaatgg
    29341 aaaaattagt tgcctataaa cgcatgcctt tgtggaataa acaaacaatg cctgaagatg
    29401 ttcagcaaaa gcacaataca aaagttggga cttgggggaa aattactgtc ttgaagggag
    29461 ctctcaagtt tattgaattg acagaagaag gggaagttct agctgaacac ctctttgaag
    29521 caggggcaga caatccaatg gcccaacctc aagcctggca ccgagtggaa gctgccacag
    29581 atgatgtgga atggtacttg gaattttatt gtaaacctga ggattatttt gctaaaaaat
    29641 acaataccaa tcctgttcat tcagaggtcc tagaggccat gcagacagtg aaacaaggga
    29701 aagctttgga tttgggttgt ggtcaggggc gtaattctct ttttctagcc cagcaagatt
    29761 ttgatgtgac ggctgtagat caaaatggac tagctcttga aatcttgcaa agcattgtgg
    29821 agcaggaaga tttggacatg cctgttggcc tttacgatat caattcagct agcattgaac
    29881 aagaatatga ttttatcgtt tcaacagttg ttctcatgtt tctacaagcg gaccgcattc
    29941 cagctattat tcaaaatatg caggagaaaa ccagtgttgg tggttacaac cttatcgttt
    30001 gtgccatgga cacggaggat tatccttgct cggttaattt cccattcacc tttaaagaag
    30061 gagaactggc agactattac aaggattggg aattggttaa gtacaatgaa aatccaggcc
    30121 atttgcaccg tcgcgatgag aatggcaatc gtattcaact acgctttgcg accttactag
    30181 ctaagaaaat caagtaaaca cacatgaaga ttaggaattt tcctgatctt ttttcttttt
    30241 tacgaatgat atagaaaagg agggaattca tgtttgttgc gagagatgct aggggagaat
    30301 tggtaaatgt gttagaggat aaacttgaga agcaagcata cacctgccca gcttgtggag
    30361 gccagctcca tttgcgtcaa ggaccaagtg tacggacgca ttttgcccat aaatccttaa
    30421 aagactgtga ttttttcttt gaaaatgaaa gtccagaaca cctggccaat aaggaatccc
    30481 tctatcactg gttgaaaaaa gagacaaagg ttcaattaga gtacccgctt tcagaactta
    30541 aacagattgc ggatgtattt gtaaatggca atctagctct agaagttcag tgtagtccct
    30601 tgcctcagaa agtccttaaa gagcgaagtg agggatatcg tagtcagggt taccaagtac
    30661 tgtggttgct gggtcaaaaa ctgtggctca aggagcgttt gactcgtcta cagcaaggtt
    30721 ttctttattt cagtcaaaac atgggctttt atgtttggga attagacaag gaaaaacaag
    30781 ttttaagact caaatacctg atttaccagg atctccgcgg taaactccat tatcaaatca
    30841 aggaattttc ctatggtcaa ggta
//
LOCUS       DAVBEM010000024        30073 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVBEM010000024 DAVBEM010000000
VERSION     DAVBEM010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30073
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.024"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            51..1100
                     /locus_tag="VQ548_001101"
     CDS             51..1100
                     /locus_tag="VQ548_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HET2653960.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAVHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(1200..5042)
                     /gene="spuA"
                     /locus_tag="VQ548_001102"
     CDS             complement(1200..5042)
                     /gene="spuA"
                     /locus_tag="VQ548_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HET2653961.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPGNANASLEKTEEKPAASPA
                     DPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDD
                     VEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVE
                     KLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQW
                     PDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQ
                     IFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHL
                     GNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGK
                     LGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDST
                     NKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDSKIDDAHKVAKAAFVDP
                     AKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDY
                     LKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSD
                     PKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDLFEDLEPNYYHFMDADGTPR
                     TSFGGGRLGTTHHMTKRLLIDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARAL
                     NPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPA
                     FITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKA
                     ENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHL
                     LRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQS
                     TDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKARE
                     FNLGTAFAHLRNAEVLADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTS
                     HESTAEEKPDSTPSKPEHQNEASHPEHQDPAPEARPDSTKPDTKVADAENKPSQATAD
                     SQAEQPAQEAQASSVKEAVRNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGI
                     SLLALLGLGFLLKNKKEN"
     gene            5459..5872
                     /gene="rpsL"
                     /locus_tag="VQ548_001103"
     CDS             5459..5872
                     /gene="rpsL"
                     /locus_tag="VQ548_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HET2653962.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            5892..6362
                     /gene="rpsG"
                     /locus_tag="VQ548_001104"
     CDS             5892..6362
                     /gene="rpsG"
                     /locus_tag="VQ548_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HET2653963.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            6787..8868
                     /gene="fusA"
                     /locus_tag="VQ548_001105"
     CDS             6787..8868
                     /gene="fusA"
                     /locus_tag="VQ548_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HET2653964.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            8972..13363
                     /locus_tag="VQ548_001106"
     CDS             8972..13363
                     /locus_tag="VQ548_001106"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HET2653965.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPAFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFESVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            13465..13728
                     /locus_tag="VQ548_001107"
     CDS             13465..13728
                     /locus_tag="VQ548_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HET2653966.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            13721..13999
                     /locus_tag="VQ548_001108"
     CDS             13721..13999
                     /locus_tag="VQ548_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HET2653967.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            14020..14172
                     /locus_tag="VQ548_001109"
     CDS             14020..14172
                     /locus_tag="VQ548_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653968.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            14194..15435
                     /locus_tag="VQ548_001110"
     CDS             14194..15435
                     /locus_tag="VQ548_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HET2653969.1"
                     /translation="MVLPNFKENLGKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFKNAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            15445..15675
                     /locus_tag="VQ548_001111"
     CDS             15445..15675
                     /locus_tag="VQ548_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET2653970.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            15898..16620
                     /locus_tag="VQ548_001112"
     CDS             15898..16620
                     /locus_tag="VQ548_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET2653971.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            16837..18171
                     /gene="pepC"
                     /locus_tag="VQ548_001113"
     CDS             16837..18171
                     /gene="pepC"
                     /locus_tag="VQ548_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HET2653972.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(18227..19138)
                     /locus_tag="VQ548_001114"
     CDS             complement(18227..19138)
                     /locus_tag="VQ548_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2653973.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(19162..19965)
                     /locus_tag="VQ548_001115"
     CDS             complement(19162..19965)
                     /locus_tag="VQ548_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HET2653974.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(19993..20982)
                     /gene="manX"
                     /locus_tag="VQ548_001116"
     CDS             complement(19993..20982)
                     /gene="manX"
                     /locus_tag="VQ548_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HET2653975.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(21215..22234)
                     /gene="adhP"
                     /locus_tag="VQ548_001117"
     CDS             complement(21215..22234)
                     /gene="adhP"
                     /locus_tag="VQ548_001117"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HET2653976.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLTLAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(22573..23385)
                     /locus_tag="VQ548_001118"
     CDS             complement(22573..23385)
                     /locus_tag="VQ548_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2653977.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            23575..24993
                     /locus_tag="VQ548_001119"
     CDS             23575..24993
                     /locus_tag="VQ548_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HET2653978.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            25046..25753
                     /locus_tag="VQ548_001120"
     CDS             25046..25753
                     /locus_tag="VQ548_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2653979.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            25848..26822
                     /gene="folP"
                     /locus_tag="VQ548_001121"
     CDS             25848..26822
                     /gene="folP"
                     /locus_tag="VQ548_001121"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HET2653980.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGITPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            26824..28146
                     /locus_tag="VQ548_001122"
     CDS             26824..28146
                     /locus_tag="VQ548_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET2653981.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGIPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            28127..28681
                     /gene="folE"
                     /locus_tag="VQ548_001123"
     CDS             28127..28681
                     /gene="folE"
                     /locus_tag="VQ548_001123"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HET2653982.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            28724..29536
                     /gene="folK"
                     /locus_tag="VQ548_001124"
     CDS             28724..29536
                     /gene="folK"
                     /locus_tag="VQ548_001124"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HET2653983.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFEFYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIYILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPTLKQPIRNLYDALKK"
     gene            complement(29581..29898)
                     /locus_tag="VQ548_001125"
     CDS             complement(29581..29898)
                     /locus_tag="VQ548_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HET2653984.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMYGRETILLPEEN
                     DLF"
BASE COUNT         8526 a         5841 c         7006 g         8700 t
ORIGIN      
        1 ttagaataat ttttcaaatt gaaggacaga gatagacaag gagaatcaca atggtagaat
       61 tgggaatttc aacatttggg gaaataacgg agcttgaagg gactggacaa acttacagtc
      121 atgctgaacg cattcgccag ttggtggcag agattgagct ggctgacaag gttggtttgg
      181 acgtatatgg gattggcgag caccatcggg cggattttgc agtatcagcc ccagagattg
      241 tcctggccgc tggggcagtc aataccaaga aaatccgttt gaccagtgca gtcagcattc
      301 tgtcaagcat ggatccgatt cgtttgttcc aacagtatgc cactatcgat gctttgtcaa
      361 atggacgagc ggagattatg gctggaaggg gctctttcac ggaatctttc cctctgtttg
      421 gttatgactt gaaagactac gactctcttt ttgatgagaa attagacttg cttcagttag
      481 tcaatgaaaa gaccaagtta gactggcaag gtcgattgac tcaaacgatt gctggtaaag
      541 aagtttatcc tcgtccagtt caggacaaat tgcccttgtg gatagctaca ggtggtcatg
      601 tcgaatcaac agtgaagatt gctcaggctg gtctaccgat tgtatatgct attattggtg
      661 gtaatccacg ttattttaaa aagttgattc aggcttatcg tgagattgga agcgaagcgg
      721 tccatgctga caaagacttg aaagtgggag cccattcttg ggggtggatt gcggaagatg
      781 gtgagcaggc ggtgaaagat tatttccatc cgactaagca agtggtggat gctatttcca
      841 aagaccgtcc gcactggcag gaattgcgtt atgagcaata tttggagcag gtagggtcaa
      901 atggcgccat gtttgttggc aatccagatc aggtggccga aaaattgatt cgcatgatag
      961 aggatttagg attggaccgc ttcatgcttc atctaccgct tggttctatg cctcatgacc
     1021 aggttctgag agctattgaa ctcttcggaa cacaagttgc acccaaagta cgagcttatt
     1081 ttgctatgaa agaggcttaa taaaaaatcc taatcaagtt tattaggaca acaaatattg
     1141 tacgaaaatt aatcccccga gctataatgc ttgggggatt tttctatagg agggctagtt
     1201 tagttctctt ttttattttt tagtaagaaa ccgagaccaa ggagcgcaag gaggctgatt
     1261 cctgcaaata ggagtttgtt ttcgttttta attcctgtat ttggaagttc agcttgtcta
     1321 tctggggttg caggtatatt tttcttgcta gagttttcta ccgattcgtt tcgaaccgct
     1381 tcttttacag atgatgcttg tgcttcttgt gctggttgtt cagcttgtga atcagctgta
     1441 gcttggctag gtttattttc cgcatcagct actttggtat ctggtttagt agaatcaggt
     1501 ctagcttctg gagctggatc ttgatgttca gggtgagaag cttcattttg atgttcaggc
     1561 ttggaagggg ttgagtctgg tttctcttct gcagttgact catggctagt tccattttga
     1621 gagactcgaa gaacagtagc tgtaagggca ttcaatttca agcctttttc agtccattca
     1681 agtcctttcg ggttggcaat tccgactgat cctgcttggt tttcatctgc caaaacttcc
     1741 gcatttctta gatgtgcaaa ggcagttccc aaattaaatt cgcgagcttt ttcatccgca
     1801 ttgacaaaga ctgcgtagat atcgccgttt ggagcagtga tttgatagcc aatcactaca
     1861 tcctcttttt ccacaccatt ttggcctggg acagtgatga ggtggacacg gtctttgata
     1921 tcttgaagac tcttaagtcg gaaggcatct gtagattgac gaagggcaat caaacctttc
     1981 atatagtcac ggctcttgac attttcagga taagctttac catctgtagc cttagtccag
     2041 tcaaacttgt tgactgcatc actagaatcg taagagtcat ggatgaagta aggatagtca
     2101 aatgggttgc cgtccttatc acgcaacaag tgagatttgt ttggaacctt atcctctgct
     2161 actggagtct tgtaggctgg gtcacggaat tgtttagtac gtccatattc ctgaccggag
     2221 tggataaatg gagttccttg agctgtcaag accatgagat ttccaagtcg taaacgacgg
     2281 tggatttcag catagttctc agccttgctt gggtcttttt tgatagactg ggcaatgatg
     2341 tcaaagaggg tcaagttatc atgggctgcg atgtattgga tgacatctcc agggctgtca
     2401 gcttcaaagt tagttggttg agcaatgaga tttttaaaga tggtgttgac atcacgcttg
     2461 ccacctgtga taaaggcagg ttgaccttcg tttggataac cagatttgag gttgttacgg
     2521 atgtcatctg aaaagacagc gacagtatcg gtatgtttca tccaatcttg gtcagcagct
     2581 ttagtaggca tgttttcatc accggcatag gttctccaac cttcaccaag catgatgagg
     2641 tttggattga gggcgcgtgc agccttgtaa gcttcttcga tagaagcggc gtcatggtct
     2701 cccatcatat cgaaacggaa gccatccact ttgtaggtat caactaggta tttgatagag
     2761 tcaattagga gccgtttggt catatggtgg gttgtcccca agcgtccacc accaaagcta
     2821 gttcgaggtg tgccatcggc atccataaag tggtagtagt ttggttccaa atcttcaaag
     2881 agatcgactt tggctgtgtg gttataaacg acatctagga tagctcccat accacgtttg
     2941 tggatttcgt tgatgaggtt tttaaattct gcgattcgtt tttctggatt cttaggatcg
     3001 cttgagtaca taccagtcaa ggagaagtag ttttgagggt catatcccca gttgtagttg
     3061 ctgttgcttg aagcgtagtc agacaagcgt tcatggtttt tcaattcatt gacaaagtag
     3121 taagacaaga ctggaaggag ctggatatgg gttacaccca agtctttgag atagtctagt
     3181 ttttcaatga aggcttcaaa agtcccaaat ggtttggtca agtcttttgc aatggcagga
     3241 tctgaagtga aatcacgcac atgagcttcg tagataacgg cgtcttcacg agtcttgaaa
     3301 ttgtgaatct taccataagt caagtcttga ggtccgagtt tagctggatc tacaaaggcg
     3361 gctttagcca ctttatgggc atcgtcaatc ttggaatcgt cgctattcca agcagcaaga
     3421 gatttagcgt aaggatcgag tgcaagaaca gttttacctt gacgctcgat ttggtattga
     3481 taatagtagc cagtgaaatc tgtgattccg agtttgtttg tgctgtctag agtttgtttc
     3541 caagttcctc tttccccttt ttcaagagcg acagttccaa ctactttgtc agggtcattc
     3601 ttgtcgtaga caacaacaga aaccttatca gcacttggtg accaaagggt caaatcaact
     3661 tgttttcctt cttcttttag gtcagctccc agtttgccat catagctgta tgtctcatct
     3721 ttcaggcgcc agcttgtttt ggtagtgaat tggtcggaat tgtagctaac agtataagga
     3781 tgttttgtgt cagagaaatc tccgctgtag gtcactttct taccagcttc atcgattgca
     3841 acatcggtaa tagttacctt gtttcctagg tgattagtga tgttggagtg tttgaggata
     3901 tcttcttttt tagcaccgac aagtgttgaa aagctacttt caatgctaga agtgcctacg
     3961 tgttgggctc ctgtcatacg gatatcatgg acatagtatg gatttgtgta aatcgattca
     4021 tcatcgtctt ttaggaaaat ttggctatga tttttcaaat ctgtgaactt ataattttct
     4081 ttacggattt tcacgtcgtc tccttgtttg ctctcatcta gtaataaaaa tccaaattct
     4141 cttgcggctt cattaagagg aatgtcgata tagcggccat atttgcctgt agccgtaaag
     4201 tctgttccgt caggccattg agcgctactt ggatttttca catctcccca gtaccagaga
     4261 gatttcttgt catagttgcc atctgtgcgg tagtagttga cgcgaacagt tcctgcaggc
     4321 tgtggctcgt aagagaaaac cttgtaatct tggtctaacc aagcttcgtt catttttgga
     4381 actagttttt ctacagattt atcgccggtt agattttttc cagctgtatt gttgatgagg
     4441 aagctaattt tcttggcttg ttctcccttt aatttgacat ctaggtaata gccgtagtca
     4501 tctttcttgg catccttgaa ggacaaagct ccgtttggcc agttttcaga tggtttttca
     4561 acatcgtccc aagtccatag tccttgagca tccttgtttt cttcaggaag ttttttgaca
     4621 tggatacgga agtagttatc ttcgatgggc tcttctgcct tagtttcagt tgttactgga
     4681 ctagtagaag tagttggctc acttgaacga tcttgtccag tttgtggtgc tggatcggct
     4741 gggcttgcag caggtttttc ttctgttttc tctagggaag cgtttgcatt tccaggtgaa
     4801 gaaatatcac tttcgttctt accagagcca gctgctgtat cagtaagagg ttgggcaagg
     4861 gtggttgtat ttctgttgtt gggttcgtta gtggttggtg tactttcgtc ggatgagata
     4921 gttggtgtag ccatggcaag caagacaagg cttgcgccga taaggacaga accagttcca
     4981 tttttgaggg aacggatgct gtagaccatt tttttctcag tgtgagatgg tgtttttctc
     5041 ataatgattc tccaatcaat aaatttctat atcagtatag catgtagtaa aacaatatgc
     5101 aagcgttttc tttgatttgt gaaagaaatt cttacttttg agaagttttc cgtactattt
     5161 tatatatcag tataaatgac ggagataaaa atgtcacgta agccaagccg tgttattagg
     5221 aagatgatgt gttctcagct atttttattc agaaattgat ctctaacatt accaataaaa
     5281 aagaaaaata tcttgacaag caagggaaaa ttttgttaca ataatagacg gtacttttta
     5341 cttttggtct ctcaagagtg tacagggacg tgctgacaaa tgttgcaaaa gtacacacag
     5401 atgatatctg tcaccaagtg tatcatcacc aaaaataaaa aaacacagga gaatgtagat
     5461 gcctacaatt aaccaattgg ttcgcaaacc gcgtaaatca aaagtagaaa aatctaaatc
     5521 accagctttg aacgttggtt acaatagtca taaaaaagtt caaacaaacg tttcttcacc
     5581 acaaaaacgt ggtgttgcaa ctcgtgttgg aacaatgaca cctaaaaaac ctaactcagc
     5641 ccttcgtaaa ttcgctcgtg tacgtttgag caaccttatc gaagttactg cctacatccc
     5701 aggtatcgga cacaacttgc aagagcacag cgtggtgctt cttcgcggtg gacgtgtaaa
     5761 agaccttcca ggggtacgtt accatatcgt ccgtggtgca cttgatactg caggtgttaa
     5821 cgatcgtaaa caaggccgtt ctaaatacgg tactaaacgt ccaaaagcat aaggaaaggg
     5881 gataaagaga aatgagtcgt aaaaatagag ctccaaaacg tgacgtattg ccagatccgc
     5941 tatacaattc acaactagtt actcgtctta tcaaccgcgt tatgcttgat ggtaaacgtg
     6001 gtactgctgc ttcaatcgtt tacggtgctt ttgagcaaat caaagaagct actggcaacg
     6061 atgcacttga agtatttgaa acagctatgg aaaacatcat gcctgtactt gaagtacgtg
     6121 cacgtcgtgt tggtggttct aactaccaag tcccagttga agttcgtcca gaacgtcgta
     6181 caacacttgg acttcgttgg ttggtaacaa tcgctcgtct tcgtggtgaa cacacaatgc
     6241 aagaccgtct tgcaaaagaa atcttggatg ctgctaacaa cactggtgca gcagttaaga
     6301 aacgtgaaga tactcaccgt atggctgaag ctaaccgtgc attcgcacac ttccgttggt
     6361 aagataggat gcgaaagcgt taagaaagtc ccagagaaaa tagggaatcg aagcaggttg
     6421 cggttgcaac caatgagatt catctttttc tccagacttt tagcttgagc tcaactaaat
     6481 catgatgcta ggaacggtaa ggatgcaagg taaaaatagg aaactgacgc agtattcgac
     6541 gaatacaagg agttttatct ttttcacgca gcatcccgtt ccagctcaca tcggctaact
     6601 aactttagcc cgggttcaaa ttagctaaat cgattagtat tagctataac tcagcttacc
     6661 atctcgtaag ttgaaaccaa caatagcatg aaaacattga gaacgggtag gtcctgccta
     6721 tccgttttta ttaaaatcgt gttataatag aatagaaatc aaaaataaat aggagaaaca
     6781 aacctcatgg cacgcgaatt ttcacttgaa aaaactcgta atatcggtat catggctcac
     6841 gtcgatgccg gtaaaacaac aactactgag cgtattcttt actacactgg taaaatccac
     6901 aaaatcggtg aaactcacga aggtgcgtca caaatggact ggatggagca agagcaagaa
     6961 cgtggtatca cgatcacatc tgctgcgacg acagctcaat ggaacaacca ccgcgtaaac
     7021 atcatcgaca caccaggaca cgtggacttc acaatcgaag tacaacgttc tcttcgtgta
     7081 ttggatggtg cggttaccgt tcttgactca caatcaggtg ttgagcctca aactgaaaca
     7141 gtttggcgtc aagcaactga gtacggagtt ccacgtatcg tatttgccaa caaaatggac
     7201 aaaatcggtg ctgacttcct ttactctgta agcacacttc acgatcgtct tcaagcaaat
     7261 gcacacccaa tccaattgcc aatcggttct gaagatgact tccgtggtat cattgacttg
     7321 atcaagatga aagctgaaat ctatactaac gaccttggta cggatatcct tgaagaagac
     7381 atcccagctg aataccttga ccaagctcaa gaataccgtg aaaaattgat tgaagcagtt
     7441 gctgaaactg acgaagaatt gatgatgaaa tacctcgaag gtgaagaaat cactaacgaa
     7501 gaattgaaag ctggtatccg taaagcgact atcaacgttg aattcttccc agtattgtgt
     7561 ggttcagcct tcaaaaacaa aggtgttcaa ttgatgcttg atgcggttat cgactacctt
     7621 ccaagcccac ttgacatccc agcaatcaaa ggtattaacc cagatacaga cgctgaagaa
     7681 attcgtccag catctgacga agagccattt gcagctcttg ccttcaagat catgactgac
     7741 ccattcgtag gtcgtttgac attcttccgt gtttactcag gtgttcttca atcaggttca
     7801 tacgtattga atacttctaa aggtaaacgt gaacgtatcg gacgtatcct tcaaatgcac
     7861 gctaacagcc gtcaagaaat cgacactgtt tactcaggtg atatcgctgc tgccgttggt
     7921 ttgaaagata ctacaactgg tgactcattg acagatgaaa aagctaaaat catccttgag
     7981 tcaatcaacg ttccagaacc agttatccaa ttgatggttg agccaaaatc taaagctgac
     8041 caagacaaga tgggtatcgc ccttcaaaaa ttggctgaag aagatccaac attccgcgtt
     8101 gaaacaaacg ttgaaactgg tgaaacagtt atctcaggta tgggtgaact tcaccttgac
     8161 gtccttgttg atcgtatgcg tcgtgagttc aaagttgaag cgaacgtagg tgctcctcaa
     8221 gtatcttacc gtgaaacatt ccgcgcttct actcaagcac gtggattctt caaacgtcag
     8281 tctggtggta aaggtcaatt cggtgatgta tggattgaat ttactccaaa cgaagaaggt
     8341 aaaggattcg aattcgaaaa cgcaatcgtc ggtggtgtgg ttcctcgtga atttatccca
     8401 gcggttgaaa aaggtttggt agaatctatg gctaacggtg ttcttgcagg ttacccaatg
     8461 gttgacgtta aagctaagct ttatgatggt tcatatcacg atgtcgactc atctgaaact
     8521 gccttcaaga ttgcggcttc actttccctt aaagaagctg ctaaatcagc acaaccagct
     8581 atccttgaac caatgatgct tgtaacaatc actgttccag aagaaaacct tggtgatgtt
     8641 atgggtcacg taactgctcg tcgtggacgt gtagatggta tggaagcaca cggtaacagc
     8701 caaatcgttc gtgcttacgt tccacttgct gaaatgttcg gttacgcaac agttcttcgt
     8761 tctgcatctc aaggacgtgg tacattcatg atggtatttg accactacga agatgtacct
     8821 aagtcagtac aagaagaaat tattaagaaa aataaaggtg aagactaatc cgtcctcact
     8881 ctagaaggaa gtcacttagt ggcttccttt tgtctttaga aaatacctct aaatatggta
     8941 aaatagtaga agaataatgt gaggaaaatg aatgtcaaat agttttgaaa ttttgatgaa
     9001 tcaattgggg atgcctgctg aaatgagaca ggctcctgct ttagcacagg ccaatattga
     9061 gcgagttgtg gttcataaaa ttagtaaggt atgggagttt catttcgtat tttctaatat
     9121 tttaccgatt gaaatctttt tagaattaaa gaaaggtttg agcgaagaat tttctaagac
     9181 aggcaataaa gctgtttttg aaattaaggc tcggtctcaa gaattttcaa atcagctctt
     9241 gcagtcctac tatagggagg ctttctctga aggtccatgt gctagtcaag gttttaagtc
     9301 cctttatcaa aatttgcaag ttcgtgctga gggtaatcag ctatttattg aaggatctga
     9361 agcgattgat aaggaacatt ttaagaagaa tcatcttcct aatttagcca aacaacttga
     9421 aaagtttggt tttccaactt ttaactgtca agtcgagaag aatgatgtcc tgacccaaga
     9481 gcaggaagag gcctttcatg ctgaaaatga gcagattgtt caagctgcca atgaggaagc
     9541 gctccgtgct atggaacaac tggagcagat ggcacctcct ccagcggaag agaaaccagc
     9601 ctttgatttt caagcgaaaa aagctgcagc taaacccaag ctggataagg cggagattac
     9661 tcctatgatc gaagtgacga cagaggaaaa tcgtctggta tttgaagggg ttgtttttga
     9721 tgtggagcaa aaagtgacta gaacaggtcg tgttttaatc aactttaaaa tgacggacta
     9781 tacttcaagt ttttctatgc aaaagtgggt taaaaacgag gaagaggccc agaagtttga
     9841 cctcatcaag aagaattctt ggctccgagt tcgagggaat gtggagatga ataacttcac
     9901 acgcgatttg actatgaacg tacaggatct gcaggaagtt gttcactatg agcggaagga
     9961 tttgatgcca gaaggtgagc gtcgggttga gtttcatgct catactaaca tgtcgactat
    10021 ggatgctttg ccagaggtcg aagagattgt tgcaacagct gctaagtggg gacacaaggc
    10081 ggttgctatc acggaccatg ggaatgtcca gtcctttcca catggctata aggcggctaa
    10141 gaaagcggga atccagctga tctatgggat ggaagccaat atcgtggagg accgtgtccc
    10201 tatcgtctat aacgaagtgg agatggactt gtcagaagca acctacgtgg tctttgacgt
    10261 ggaaacgacg ggactttcag ctatctataa tgacttgatt caggttgcgg cttctaagat
    10321 gtacaagggg aatgttattg ctgaatttga tgaatttatc aatcctgggc atcccttgtc
    10381 agcctttact acagagttaa ctggaattac agatgatcat gtcaaaaatg ccaaaccact
    10441 agaacaagtt ttgcaagaat tccaagaatt ttgcaaggat acggtcctag ttgcccacaa
    10501 tgctaccttt gacgttggct ttatgaatgc taattatgag cggcatgatc ttccaaagat
    10561 tagtcagcca gttattgata cgctggagtt tgctagaaac ctctatcctg agtataaacg
    10621 ccatggtttg gggcctttga ccaagcgttt tggtgtggcc ttggaacatc accacatggc
    10681 caactacgat gcggaagcga ctggtcgtct gcttttcatc tttatcaaag aggtagcaga
    10741 aaaacatggt gtgaccgatt tagctagact caacattgat ctaatcagtc cagattctta
    10801 caaaaaagct cggatcaagc atgcgaccat ctatgtcaag aatcaggtag gtctaaaaaa
    10861 tatctttaag ctggtttcct tgtctaatac caagtatttt gaaggagtgc cacggattcc
    10921 gagaacggtt ctagatgccc atcgagaggg cttgatttta ggttcagcct gttcagaggg
    10981 tgaagttttt gacgtggtcg tttctcaagg tgtggatgcg gcggttgagg tggccaagta
    11041 ttatgatttt atcgaggtca tgccaccggc tatctatgca cccttgattg ccaaagagca
    11101 ggtcaaggat atggaggaac tccagaccat tatcaagagt ttgatagagg ttggagaccg
    11161 ccttggcaag cctgttctgg ctacgggaaa tgttcactat atcgaaccgg aagaagagat
    11221 ttatcgtgaa attatcgtcc gtagtttggg acagggtgcg atgattaatc gaactatcgg
    11281 tcatggtgaa catgcccaac cagcaccact tccaaaggct cattttcgaa cgactaatga
    11341 gatgttggat gaatttgcct ttttgggaga ggaactggct cgtaaactgg ttattgaaaa
    11401 caccaatgcc ttggcagaaa tatttgaatc cgttgaagtc gttaagggtg acttgtatac
    11461 gcctttcatc gacaaggctg aagaaacagt tgctgagttg acctataaga aagcttttga
    11521 gatttatgga aatccgctgc cagatattgt tgatttgcgg attgaaaaag aattaacatc
    11581 catactgggg aatggatttg ctgtgattta tctggcatcg cagatgctgg tgcaacgttc
    11641 taatgaacgg ggttatttgg ttggttctcg tgggtctgtc ggatctagtt tcgttgcgac
    11701 catgattggg attacggagg tcaatcctct ctctcctcac tatgtctgtg gtcagtgtca
    11761 gtacagtgag tttatcacag atggttcgta cggttcagga tttgatatgc cccataagga
    11821 ctgtccaaac tgtggtcaca aactcagtaa aaacggacag gatattccgt ttgagacctt
    11881 ccttggtttt gatggggata aggttcctga tattgacttg aacttctcgg gagaagatca
    11941 gcctagcgcc cacttggatg tgcgtgatat ctttggtgaa gaatatgcct tccgtgcggg
    12001 aacggttggt acggtagctg ccaagactgc ctatggattt gtcaagggtt acgagcgaga
    12061 ttatggcaag ttttatcgtg atgcagaagt agaacgcctc gctcaaggag cggcgggtgt
    12121 caagcggaca acaggccaac acccgggggg aatcgttgtt attccgaact acatggatgt
    12181 ctacgatttt acgcctgtcc agtatccagc agatgatgtc acggctgaat ggcagaccac
    12241 tcactttaac ttccacgata tcgatgagaa cgtcctcaaa ctcgatgtac tgggacatga
    12301 tgatccgacc atgattcgaa aacttcagga tttgtctggt attgacccta ataaaattcc
    12361 tatggatgac gaaggcgtga tggcactctt ttctgggact gatgtactag gggtaacacc
    12421 tgaacaaatt ggaacgccta cgggtatgtt ggggattcca gagtttggaa caaatttcgt
    12481 acgtggaatg gtagacgaaa cccatccgac aacctttgcg gaattgcttc agctgtctgg
    12541 tctgtcccac ggtactgacg tttggttggg gaatgctcag gatctgatta agcaaggaat
    12601 agcggaccta tcgactgtta tcggttgtcg ggacgacatc atggtttacc tcatgcatgc
    12661 gggtctggaa cctaagatgg cctttaccat tatggaacgg gtacgtaagg gtttgtggct
    12721 aaagatttca gaagaggaga gaaatggcta tatcgaagcc atgaaggcta ataaggtgcc
    12781 agagtggtat atcgaatcct gtgggaaaat taagtacatg ttccctaagg cccatgcggc
    12841 agcctacgtt atgatggcct tgcgtgtagc ttacttcaag gttcaccatc ctatttatta
    12901 ctactgtgct tacttctcca ttcgtgctaa ggcttttgat atcaagacca tgggtgcggg
    12961 cttggaggtc atcaagcgca gaatggaaga aatctctgaa aaacggaaga acaatgaagc
    13021 ctctaatgtg gaaatcgatc tctatacaac tcttgagatt gtcaatgaga tgtgggaacg
    13081 aggtttcaag tttggtaaat tagatctcta ccgtagtcag gcgacagagt tcctcatcga
    13141 cggggatacc cttatcccac catttgtagc aatggatggt ctgggagaga acgttgccaa
    13201 gcaactggtg cgggcgcgtg aagagggaga attcctctct aaaacagaac tacgcaagcg
    13261 tggtggactc tcatcaacct tggttgaaaa gatggatgag atgggtattc ttggaaatat
    13321 gccagaggat aaccagttga gtttgtttga tgagttgttt taaaaaattg cttaataatc
    13381 tattaaaaga ggctaacgta tatccaatag atttacatta gctttctttt ttgttaaaat
    13441 agtctatgga aagagggtga gagtatgtca aagatgagta taagcatccg tctggatagt
    13501 gaggttaagg agcaggccca acaggtgttt agtaatctgg gaatggatat gacaacagct
    13561 attaatattt tccttcgtca ggcaattcaa tatcagggat taccttttga tgttagacta
    13621 gacgaaaatc ggaagttgct ccaagcgtta acggatttag accaaaatcg taatatgagc
    13681 cagtcttttg aatcagtctc agatttgatg gaggacttac gtgcttaaga ttcgttatca
    13741 taaacagttt aaaaaagatt ttaagttggc tatgaagcgt ggtttgaagg cagaattatt
    13801 agaagaagtt ttgaattttc tggttcaaga aaaagaacat cctgccagat atcgtgatca
    13861 ttcattgacg gcatccaagc attttcaagg agttcgtgaa tgccataccc agccagattg
    13921 gcttttggtt tataaagtag acaagtcgga attgatttta aatttgctga ggacaggcag
    13981 tcacagtgat ttattttaat ctattttaag ggggttctca tgaaactaag aatatttgcg
    14041 gaagataagc cggctaagaa ggtatttgaa tatcaattag aacttgctga tcgtacaatt
    14101 cttctatcga cagcactctt gtcaggtgct attgctttag caggaatctt ttctgctttg
    14161 aaagaaaaat aaaaatagaa aagagaaaac agaatggttt taccaaattt taaagaaaat
    14221 ctaggaaaat atgcgaaatt gttggttgcg aacggaatta acgtgcaacc tggtcacact
    14281 ttggctctct ctattgatgt ggagcaacgt gaattggcac atctaatcgt gaaagaagct
    14341 tatgccttgg gtgcgcatga ggtcatcgtt cagtggacag atgatgtgat taaccgtgag
    14401 aaattcctcc atgccccgat ggagcgtttg gacaatgtgc cagaatacaa gattgctgag
    14461 atgaactatc ttttggagaa caaggctagc cgtcttgggg ttcgttcatc tgatccaggt
    14521 gccttgaacg gagtggacgc tgacaagctt tcagcttctg ctaaagctat gggacttgcc
    14581 atgaagccta tgcgtatcgc aactcaatct aacaaggtta gctggactgt agcagccgct
    14641 gctggacttg agtgggctaa gaaagtcttc ccaaatgctg cgagcgacga agaagcagtt
    14701 gatttccttt gggatcaaat cttcaaaact tgtcgtgtct acgaagcaga tcctgttaag
    14761 gcttgggagg aacatgcagc cattctcaag agcaaggccg atatgcttaa taaggagcaa
    14821 ttttcagccc ttcactacac agcgccagga acagatttaa cacttggttt gccaaagaac
    14881 cacgtttggg aatcagctgg tgctgtcaat gcacagggcg aagaattctt gccaaatatg
    14941 ccgacagaag aggtcttcac agcgcctgac ttccgtcgtg cagatggtta tgtcacttct
    15001 acaaaaccgc ttagctacaa cggaaatatc attgaaggca ttaaggtgac ctttaaggat
    15061 ggacaaatcg tagatatcac tgctgagaag ggtgatcagg ttatgaaaga ccttgtcttt
    15121 aaaaatgcgg gtgcgcgtgc cttgggtgaa tgtgccttgg taccagatcc aagtccaatt
    15181 tctcagtcag gcattacctt ttttaacacc cttttcgatg aaaatgcgtc aaaccacttg
    15241 gctatcggtg cagcctatgc gactagcgtt gttgatggag cggagatgag cgaagaggag
    15301 cttgaagctg cagggcttaa ccgttcagat gttcacgtag actttatgat tggttctaac
    15361 caaatggata tcgatggtat tcgtgaggat ggaacgcggg tacctctttt ccgtaatggg
    15421 aattgggcaa attaaggaga taatatgtta ggaagtatgt tcgttggtct cctagtggga
    15481 tttttagcag gtgctatgac caatcgtgga gagcgaatgg gatgttttgg aaaaatgttt
    15541 ctcggttgga tcggagcctt tctaggtcac ttgctctttg gaacttgggg gccagtttta
    15601 tcaggaacag ctattatccc agcgatttta ggagccatga ttgttttagc tattttttgg
    15661 agacgaggaa gttaatttcc taaatctgat actcaatgaa aatcaaagag caaactagga
    15721 aactagccgc aggttgctca aagcactgct ttgaggttgc agatagaact gacgaagtca
    15781 gtaacatata tacggcaagg cgacgttgac gcggtttgaa gagatttttg aagagtatga
    15841 aacgaaaagg aggttggtca ttgtactagc ctccttttga tatgatataa tagttctatg
    15901 agattagata aatttttagt tgcctgtgcg gtgggaagtc ggactgaggt caaaaacttg
    15961 ctcaaggctg ggcgcgtgac tgtaaatggt aaaaaagaaa aatcagctaa attgcagatt
    16021 gatgaaaaaa tagatgagat tcgctttgat gggcaagtgt tggagtatga agagtttgtc
    16081 tactacatga tgaacaagcc caaaggagtt atctcagcga ctgaggatcc caagcacaga
    16141 accgttctgg acttgttgga tgacttggcg cggagtaagg aagtttttcc agtaggacgc
    16201 ttggatattg acacgcatgg tcttttgctc ttgaccaata atggtcagct ggctcatgtt
    16261 cttctttcgc ccaagcgtca tgtggacaag acttatcagg ctcaggtcaa gggaattatg
    16321 acccaagaag atgtggagac atttatcaag ggcattccgc tcaaagactt tacctgtcag
    16381 cccgctagac tggagattct ttccacagat gcagaaaaga atcagagcca aatccgtgtg
    16441 accattgcag aagggaagtt tcatcagatc aagcgtatgg tgggctactg tggcaaggaa
    16501 gtggtggact tgcaacgatt gactatggga actttagtat tagatgagaa cctggaacga
    16561 ggggaatggc gtcgcttgac caaggaagaa ttagaaattc tccgcgctaa tattatttaa
    16621 tttagtttaa tactcaatga aaatcaaaga gcaaactagg aaactagccg caggctgtac
    16681 ttgagtacgg caaggcgacg ttgacgtggt ttgaagagat tttcgaagag tataaattcg
    16741 aaaaaggtga gggacaatgt cctcgccttt tatgtttttt agttgcttcc tttgtgaaaa
    16801 gagttataat agactgtaga ataaaaggag gaatctatga acgcgattca agaatcattt
    16861 actgataaac tatttgccaa ctatgaagca aatgtaaaat accaagcgat tgaaaatgct
    16921 gccagccaca acggaatttt tgcagctctg gaatgtcgcc aaagccatgt agacaacaca
    16981 cctgttttct cattggattt aaccaaggac aaggtcacta accagaaagc gtctggtcgt
    17041 tgctggatgt ttgcggctct caacaccttc cgccacaaac tcatctcgca atacaaattg
    17101 gagaactttg agttgtcaca agcccacact ttcttctggg ataagtatga gaaatcaaac
    17161 tggttcttgg agcaagtcat tgcgacttca gaccaagaat tgactagccg caaggttagc
    17221 ttcttactcc aaacacctca acaagatggc ggtcaatggg atatggtcgt ttccctcttt
    17281 gaaaaatacg gtgtcgtgcc taagtcagtt tatcctgagt ctgtttcatc tagcagcagt
    17341 cgtgagctaa atgcgatcct taataaattg cttcgtcaag atgctcaaat cttgcgtgat
    17401 ttgcttgttt ctggtgcaga tcaagcgact gttcaagcta agaaagaaga cctcttgcaa
    17461 gaaatcttta actttcttgc tatgtcatta ggacttccac cacgcaagtt tgactttgct
    17521 tatcgcgata aagataacaa ctataaaagt gaaaaaggaa tcacaccaca agagttttac
    17581 aagaaatatg tcaatcttcc tttagaagac tacgtttctg ttatcaatgc tccaactgct
    17641 gataaacctt acggaaaatc ttacacagtt gagatgttgg ggaatgtggt tggtagccgt
    17701 gcagttcgct acatcaacgt tccaatggag cgcttgaaag aattggcgat tgcccaaatg
    17761 caagcaggtg agactgtttg gtttggttct gatgtcggcc agctcagcaa ccgtaaggct
    17821 ggcatccttg cgacagatgt ttatgacttt gaatcaagca tggacattaa acttactcaa
    17881 gacaaggctg gacgtttgga ctatagcgaa agcttgatga cccacgccat ggtcttgaca
    17941 ggtgttgact tggacgaaaa tggtaaatca accaagtgga aggttgaaaa ctcatgggga
    18001 gacaaggtcg gtacagatgg ttactttgtt gcctcagacg cttggatgga cgaatacaca
    18061 taccaaatcg ttgttcgtaa ggaattgctg acagcagaag aacaagctgc ctatggagca
    18121 gaaccaatcg tacttgcacc atgggatcca atgggagcct tggctgaata aaagcataga
    18181 aaaaaggaat cagattttag aacctggttc ctttttagtt gcttgattac atgatgtgaa
    18241 gaacatgtgc cacaataccc actgcgaaga gggcaaggat aatagtgatt ggagatactt
    18301 ttttcttaag taagtacatg caaagtaaag taaggagtag tcctgataat ccaggaatca
    18361 acatatccaa gttttgttgg aaagtagtaa ctttttcagg agtttgagac aatccttgtc
    18421 ctacttgtgc gaatgcttct tggatacctt tagacccttc tggcaattta tcccaatgga
    18481 tataagcctt ttcatctagt tgaactttag aaacatcgaa agcaaattta atatttaccc
    18541 agcgttgaac aaggacagca agaatgaaca tcccaaggat agaagctcct ttagtgatat
    18601 cttgaaggat accaccagac atatctttag tgatttctga tccagccttg tatccaatct
    18661 cttgaacata ccacaagaat gacatacgaa tcaagttcca tgcaacaaag aagaggagtg
    18721 gccccaagat attgccagta agggcaagtg aagcaccgag agatccaagg attgggcgta
    18781 ctgtaaacca gaatactggg tcaccgatac cagcaagagg tcccatcata ccgattttaa
    18841 ccccttggat agcagcgtca tcgatttcca caccgttagc acgttcttct tcaagcgcaa
    18901 gagtaacccc catgactgga gcagctacgt atggatgagt gttgaagaac tcaaggtgac
    18961 gctcaagagc agcgatttga tcttcttttt tagtatagag ttttttgata gctggaatga
    19021 gtgtataagc ccagcccaag ttttgcatcc gttcaaagtt ccaagaccct tgtaagaagg
    19081 ttgaacgcca ccaaactttt ttacgatctg atttagttaa ttgaagtttt tcagtcatga
    19141 tgttttcagt cctttcttat cttagtagtc ttctaggata tcgccgattg ggtcgttaga
    19201 agttgcggct cctccgccac catttccacc agttttagaa aggtgaaggt agataagagc
    19261 gatagcaaca ccgatagcac cgaatccgat tagagtaata tctgacacag cagcaagaac
    19321 gaaaccaaga gcgaagaatg gccatacttc acgagttgcc atcatgttga taaccatggc
    19381 gtaaccaacg gcaacgacca taccaccacc gatagccata ccatctttga gccagtctgg
    19441 catggcacta aggatacttt gtacagtttc agttggtacc ataaggagaa gagctgcagg
    19501 aagcgcgata cgaagtcctt ggaaaagtag cgcaatgaaa tgagcacgct ccacagcgcc
    19561 gaagtcacct tttttagcgg cagcatcagc agtgtgaacc aatccaactg aaattgtacg
    19621 aacaatcata gttaagaata gaccagctac ggcaagaggg atagcaaccg cttgggcaac
    19681 accgatacca gtcttggtaa agtcaccacc aagaaccatg ataatggcag cagcgacaga
    19741 agcaagtgca gcatcaggag cgatagcagc accgatattt gaccaaccaa gggcaatcat
    19801 ttgaagcgat ccaccgagga taatccctgc ttccaagtga cctgttacaa gcccaataag
    19861 ggtacaggct acaagtggtt ggtgaaattg gaactggtcg aggatgcctt caagacctgc
    19921 aaagaaggct acaacgacta ctaaaaccat agaaataata gacatgttta aaatcctttc
    19981 ataaataatg gcttatttga cattggcttt gttaatcaag tcaaacaaat cttttttaga
    20041 atcatttggt actttacgga catcaaattc aacacccaag tcacgcattt tttcaaatgt
    20101 agcaacatct tctttgtcca tagacaaaac ggtattgacc aatgttttac ctgttgagtg
    20161 agccatagaa ccaacgttaa gagtcttgat tggcacgccg ccttcgatgg cacgaagggc
    20221 atcttgaggt gtttcaaaca agataagggc atgtgtttct ccaaaacgtg ggtcttttga
    20281 aatctcaatc agtttttgaa ttggaaccac gttagccttg acattacctg gagctgcttg
    20341 tttaatcaat tctttacgaa ggtcgtcttt agccacgtta tctgaagcaa cgatgatacg
    20401 atttgctttt gaatctggag tccaagcagt tgcaacctga ccgtgaagta gacgtgtgtc
    20461 aagacgggca agattgattt tcaatttacc gtctccgata acagttcctt ctgggatagc
    20521 agtttgggca actggagcag ctgcagcgct tgcaacttct tcaactggat ttagctcttc
    20581 tggaagagct ttgatgccat ctttggcttc tttaatgata ttagcagcga ctttttctac
    20641 acctgcagca gcgtccatga ggcgctctgt gtaggcttga atcaacatcg gtaagttaag
    20701 tcctgtgatg atggcaaact tacgctcagg attttctccc atcacgcgac tagcttggtt
    20761 aaatggagaa ccactccaaa ggtcagccaa aactagaacc tcatcttctg cgtcaaatgc
    20821 agcaacagcg ttattaaact tagcgtatag atcatcagga ccttcatttg gcataaaggt
    20881 cacaacttga accttttctt gttcaccaaa gatcatagat cctgactgat gaatacccgc
    20941 agcaaattcg ccgtggctcg caataatgat tccgatactc attattgtca ttcctccttt
    21001 tttgttttag ttttcattta agaaaacttt aagactgttt aagtataaac cgttttcata
    21061 aaaaaagcaa ctatttatca taaaaaatta aaaaattttt atttttgtat gttgatatgt
    21121 tgagtttttg aggagtaatc ttgaattctt atttaaaatt taatataaaa aagttggaag
    21181 aagcttccaa cttttaaaat aggtttctat taaattagtg ggtgaagtcg agtaccatac
    21241 gtccttggat ttggcctttt tccatttcgt cgaaaatggc aacagcatct tctactggac
    21301 gtttttgaac aactgggact accagacctt ctgcaccaaa ttggaaggct tcttctaagt
    21361 ctttacgagt tccgacaaga gaaccgatga cttggattcc atcgaggact gttttaacga
    21421 tgctgagttc catcatttca gaaggaagac caacagcgac gacgcgacca ccagcacgaa
    21481 tggagtcaac agcctggttg aaggcaactt tagacacagc agttacgaca gctgaatgag
    21541 ctcctccatc agttttttct ttaatgagtc cagctacatc ttcaacttcg aggccgttaa
    21601 tcacaatgtc agcgcctact tcttttgcaa gggtaagttt gtcattgttg atatcgactg
    21661 cgataacatg agcattgaat acttttttag cgtattgaac agcgaggtta ccaagtccac
    21721 cagcaccgta aagaacaacc cattggcctg gttcaacttt tgcttctttg atagctttat
    21781 aggttgttac tccagcacat gtgatagaag aagcttgggc tggatcaagt ccgtcaggaa
    21841 ctttgacagc atagtcagca gttacgatac attgttcagc cataccaccg tctactgagt
    21901 agccagcatt tttcactgta cggcaaaggg tttcgcgacc agttgtacag tattcgcaag
    21961 tgccacatcc ttcaaagaac caagcaacgc tgacgcggtc accgacttta aggcttttca
    22021 catctggagc aatctcttta acgataccga taccttcgtg cccaagaaca cgtcctggga
    22081 cttgaccaaa gtcaccatga gcaacgtgga ggtcggtgtg gcaaacgcca cagtattcaa
    22141 cttctacaag tgcttcccca gtttcaagtg gacggagtac tttttcttca atagcaacac
    22201 cagtgctttc tggatttaca acaacagctt tcatagctat cctccttgat attgaccgag
    22261 aacagggaca acgggactgg attgattttt tgtcaacaga gtcgagtgtg acgagctctc
    22321 ttgtatttat atgtgaagta tatcacaaaa ggaagccttt tccaaggttt tggagacaaa
    22381 aagtagaaca atcgattaac tggttgatga gactgtgaaa agagcacaaa gaccagcttg
    22441 caagctggtc atactcttcg aaaatctctt caaaccacgt cagcttcatc tacaacctca
    22501 aagcagtgct ttgagcaacc tacggctagc ttcctagttt gctctttgat tctcattgag
    22561 tatcagtata ggttataaga ataagtcttg tagggttttg gcaaccccat cttggtcgtt
    22621 ggtaagggaa atttgctcat ctgcataagg gagtagctct ggattggcat ttttcatggc
    22681 ataacccttc ccagcaaaag cgagcatttc ggtatcattg tgttcatctc caaaggcaat
    22741 caaatctttt ttgtcacgat tcattatctt gagcaagtag tccaaagcaa aggccttgtt
    22801 gacacctttt ggggtacatt caaggatatt gagcggacct ccccaggtat tgatagaaag
    22861 ttgatgctgg tagaaggcgt tcatttcttt tgccaaggca tatttgtcac tggctctggt
    22921 ctgcaagagg atacagttag ggtccttggt caccaattca ggctggaatt gatcttcagg
    22981 ctggaaagct tctacaccaa atagtttggg attggcaatt tcttcattgg gatttgtaat
    23041 gtagaatttt ttacgatatt ctccagcgat aaaatcggct tgaatgtcct ctgaacgttg
    23101 aaccatatct agcagatatt ttttgtctac agtcaaacac ttttcaaaat cccaaacttg
    23161 gtctggtaaa tgagtaaggg atccgttgaa gttaatcata ggagtgtcta agcccagttc
    23221 acggtaaaaa tcttttgaca tacggtaagg gcgacctgtc gtaataataa cctgatggcc
    23281 tttttcagca acttttttga tggttctttt ggtaaagtca gaaatttgac tgtctgagtt
    23341 gagcagggtt ccatccaggt caactgcaat aatttttttc gtcatatgga cctttctagt
    23401 gtgttttcag ataagatgtc ttctattata acagaaagca ggcagaaaag cagattccaa
    23461 acaaaaaatg aaattggatt aatttcttaa acaaatcaaa caaagacatt gaaaaagtga
    23521 atgataaatg atataattct attattgttc gtaaaaatta aaaggagatt gatgatggac
    23581 aaattattta aactaaaaga gaacggtaca gacgttcgta cagaggttct cgctggttta
    23641 acaactttct ttgcaatgag ctatattctc tttgtaaacc cacaaatact ttcacaaaca
    23701 ggaatgcctg ctcagggcgt cttcctagcg acgattattg gtgcagtagc gggtaccttg
    23761 atgatggctt tttatgctaa cttaccttat gcccaagcac caggtatggg actcaatgcc
    23821 ttctttacct ttacagttgt attcgggctt ggttattctt ggcaagaagc cctagctatg
    23881 gtcttcatct gtgggattat ttcattgatt attaccttga caaatgttcg taaaatgatc
    23941 attgaatcga ttcccaatgc tcttcgctca gctatttcag ctggtatcgg tgtcttcctt
    24001 gcctatgtag ggattaagaa tgctggactt ttgaaattca cgattgatcc aggcaactat
    24061 actgttgtag gagaaggggc tgacaaagct caagcaacga ttgcagcaaa ctcttcagca
    24121 gttccaggat tggtcagctt taataatcca gctgttttag tggctcttgc aggacttgcc
    24181 attactatct tctttgtcat caaagggatt aaagggggaa ttattctctc tatcttgaca
    24241 acaactgttc ttgctattgc agttggtttg gttgatttgt ctagtatcga ttttgctaat
    24301 aaccatgttg gtgcagcttt tgaagatttg aagacaatct ttggtgcagc tcttggttca
    24361 gaaggtttgg gagctttggt ttcagataca gctcgcttgc ctgaaactct gatggccatt
    24421 cttgccttct cattgacaga tatttttgac acaattggta ccttgatcgg tacaggtgaa
    24481 aaagttggta ttgtagcgac aaatggtgaa aatcaccaat cagccaaatt ggataaggct
    24541 ctttactctg atttgattgg aacgacagtc ggtgccattg caggtacttc aaacgtaacg
    24601 acttatgttg agtctgctgc tggtatcggt gcaggtggac gtactggttt gacagccttg
    24661 gttgtagcta tctgttttgc gatttcaagc ttctttagcc cacttctagc gatcgtacca
    24721 acagcggcta cagctccaat cttgattatc gttgggatta tgatgcttgg tagcttgaaa
    24781 aatatccatt gggatgatat gtctgaagca gttcctgcct tcttcacatc tatctttatg
    24841 ggattcagct actctatcac tcaagggatt gcagttggtt tcttgactta cactttgact
    24901 aagcttgtca aaggtcaagt taaagatgtt catgccatga tttggatttt ggatgccttg
    24961 tttatcctta actacatcag catggcctta taatagaatg acccaggggg atttcccccc
    25021 ttttttaata caaaggagat aggtgatgaa agagaaaaat atgtggaaag aattgttgaa
    25081 tcgtgcaggc tggattttgg tctttttact tgccgtcctt ttatatcagg ttcccctagt
    25141 ggttacctct attttgactt taaaagaagt agccctgcta cagtcagggc tgatagttac
    25201 tggcctttca attgtggttc tggctctatt tattatggga gctcgtaaaa ccaagttagc
    25261 tagttttaat ttttcttttt ttagagctaa agatttggca cgtttgggct tgagttattt
    25321 agttattgtc gggtcaaata tacttggttc tatcttgttg caactgtcaa atgagacgac
    25381 aacagctaac cagtctcaga ttaacgatat ggttcagaat agttctctga tttctagctt
    25441 cttcttgcta gccttgcttg ctccaatttg tgaggaaatc ttgtgccgtg ggattgttcc
    25501 taaaaagatt ttccgaggca aggagaactt gggatttgta gtcggtacga ttgtgtttgc
    25561 tttattgcat caaccaagta atttaccttc tttattgatt tatggaggta tgtcgacagt
    25621 tctatcttgg acggcctaca agacccaacg tttggaaatg tcgatcttgc ttcacatgat
    25681 tgttaatggg attgctttct gtttgttggc tcttgtggtg attatgagtc ggacattagg
    25741 aatttctgtg taaaagtttt tatgtaggaa ccgacctctt tctactaggg aaagatgaat
    25801 gcaatcgtgt ccatcttttt ctttttatgg taaaatagaa aaataatatg atgaaaatcc
    25861 ttgagggagt gaccgatatg tcaagtaaag ccaatcatgc aaagacagtt atttgcggaa
    25921 ttatcaatgt aaccccagac tccttttcgg acggtggtca attttttgct cttgagcagg
    25981 cactccagca ggctcgtaaa ttgatagcag aaggagccag tatgctcgat atcggcggag
    26041 aatcgactcg gccgggcagt agctatgttg agatagaaga ggaaatccag cgtgttgttc
    26101 cagtgatcaa agcgattcgc aaggaaagtg atgtccttat ttctatcgat acttggaaaa
    26161 gtcaggtggc agaggctgct ttggctgctg gtgccaatct agttaatgat atcactggtc
    26221 tcatgggcga tgaaaaaatg gcccatgtgg ttgctaaagc tggagcgaaa gtagtcatca
    26281 tgtttaatcc agtcatggct cgacctcaac atcctagttc gcttatcttc cctcattttg
    26341 gctttggtca aacctttaca gaaaaagagt tagctgactt tgaaacattg ccaatcgaag
    26401 acttgatggt ggctttcttt gaacgagcac tagcgagagc ggcagaagct ggtattacac
    26461 cagaaaatat cctgttggat ccaggaattg gctttggtct gaccaagaaa gaaaatctcc
    26521 tccttttacg ggacctggat aaactacatc agaagggcta tccaatcttt ctcggagtgt
    26581 cgcgcaagcg atttgtcatc aatatccttg aagaaagtgg gtttgaagtc aatcctgaga
    26641 cagagcttgg tttccgaaat cgggacacgg cttcggctca tgtaactagt atcgctgcga
    26701 gacagggtgt agaagtggtg cgcgtgcatg acgtagctag tcacaggatg gcagttgaaa
    26761 ttgcctctgc cattcgtctg gctgatgaag cggaaaattt agatttaaaa caatataaat
    26821 aagatgaaag aaattgaaaa caatcagtgg attgctaact accggacgga tcaaccgcat
    26881 tttggattgg aacgaatggt ggaactgtta gctttgcgtg gcaatcccca tctcaaactc
    26941 aaggtcctcc atatcggagg gactaacggc aagggctcga ctattgcttt tttgaaaaag
    27001 atgctagaaa agctagggct gagagttggc gtgtttagct cgccctatct cattcattac
    27061 acagaccaga ttagcatcaa tggggaatcg atctcagaag cgaggctaga agctctcatg
    27121 gcagactatc agtctttgct ggagggagaa gcggtcgcca atttacaggg cacaaccgag
    27181 tttgagatta tcacagccct ggcctatgac tactttgcct cagagcaagt agatgtggcc
    27241 atcatggaag ttggcatggg tggacttttg gatagtacca atgtctgtca gcccattttg
    27301 acaggaatta caactattgg cttggatcat gtggccctac ttggtgacac cttggaggcc
    27361 atagcagagc agaaggcagg tattatcaaa caagggatac ccttggtaac agggcgtatt
    27421 gctccagaag ccttgactgt gattgaccgc attgcggaag ggaaagatgc gccgagactt
    27481 gcctacggga cagattatca ggttcgtcat caagaaagtg tggtgacagg ggaagtcttt
    27541 gactatacaa gtgctgtcag acaaggtcgc ttccagacta gcctgcttgg tttgtaccaa
    27601 atagagaatg ctgggatggc catagcttta cttgatactt tttgtcaaga agatggtcga
    27661 gagctagcaa gcaatgactt tcttggtcaa gccttggaag aaacaagttg gccagggcgt
    27721 ttggaaatcg tgtcaagaga tcccttgatg attttggatg gagcccataa tccccatgct
    27781 atcaaggcct tgttggtaac cttgcaagaa cgttttgcgg attatcataa ggaaatcctc
    27841 ttcacttgta tcaaaaccaa agccttggag gatatgttgg acttgctggg agccatgcca
    27901 gataccgagc ttactctaac acattttgcg gatagtcggg cgacggatga aagcgtgctg
    27961 aaagaggcag ctaagtctag aaatctcagc taccaagatt ggcatgattt tctagagcag
    28021 aatttgacag ataaaaaaga agagaaacaa acagttagga ttgtcacagg ttccttgtat
    28081 ttcttgagcc aagtgagggc ctatctgatg gagaggaaga acgagaatgg atacacaaaa
    28141 gattgaagca gctgtaaaaa tgattatcga ggctgtagga gagaacgcta atcgcgaggg
    28201 cttgcaggaa acacctgctc gtgtagcccg tatgtatcaa gagatttttt caggtcttgg
    28261 tcaaacagca gaggaacatt tgtcaaaatc ctttgaaatt attgacgata atatggtggt
    28321 agaaaaggat atctttttcc ataccatgtg tgaacaccac ttcttgccat tttatggtag
    28381 agcgcacatt gcctacattc cagatggtcg tgtggcaggc ttgtctaagc tagcccgtac
    28441 ggttgaagtt tattcgaaaa aaccacaaat tcaagaacgt ttgaatatcg aagtggccga
    28501 tgccttgatg gactatctag gtgctaaagg agcctttgtt gtcattgagg cggaacatat
    28561 gtgtatgagt atgcgtggtg ttagaaaacc aggcactgca accttgacga cagtagctcg
    28621 tggtctattt gaaacagata aggacctccg cgaccaagct tatcgtttaa tggggctata
    28681 aaaagaatcc gcttcaagcg gatttttcta gaaaggaatc attatggatc aactgcagat
    28741 taaggatttg gaaatgtttg cctatcatgg tctttttcct agtgagaaag aattggggca
    28801 gaaatttgtc gtttcagcca tcctatccta tgatatgacc aaggcagcta cagacttgga
    28861 tttaacagcc tctgtccatt acggagaatt atgtcagcag tggacgactt ggtttcagga
    28921 aacgagtgaa gatttgattg aaacggtagc ctataaactg gtggaacgta cctttgagtt
    28981 ttatcctctt gtccaagaaa tgaagttgga actgaaaaaa ccttgggcac cggtgcattt
    29041 gtcactagat acttgctcgg taaccattca tcgccgcaag caacgagcct ttatcgccct
    29101 aggaagcaat atgggagata aacaagcaaa cttgaagcaa gccattgaca aactgcgagc
    29161 tcgtggcatc tatattctca aagagtccag tgtcttagcg acggagcctt ggggtggagt
    29221 ggagcaggat agctttgcca atcaagtggt tgaggtggaa acctggctac cagcacaaga
    29281 cttgttagaa accttgttag ccattgagtc agagctggga cgggtgagag aagtgcattg
    29341 gggacctcgt ttgattgatt tggacttgct ctttgtggag gaccagatcc tttatacaga
    29401 cgacctcata ttgcctcatc cttacatagc ggaacgcctt tttgtccttg agtccttaca
    29461 ggaaattgcg cctcatttta tccatccgac attaaaacaa ccgatccgca acttgtatga
    29521 tgctttgaaa aaatagaaaa actctagttt tcagttactt gcaactgaag gctagagttt
    29581 ttaaaatagg tcattttctt ctgggaggag gatagtttct ctaccgtaca tgtctaaaac
    29641 cagtactctt gggggataac gagggtcgaa aggatggtta aagtcaaaat caatggctgt
    29701 agggaggtgt tgacttgaaa agtggaaggt aatctttcct tggttattaa gcaattgaaa
    29761 ctcgagttct tcttccaatt caaagacatt ttttaagaaa tgatcgatga tataccaaaa
    29821 agagtcaatg atgtcatcgg gcaagctggt aacaatgcca aaactagcag accgcatgtg
    29881 ggtattggta aaagccatat ctctgtcccc tttcttttcc cttatcatac agcaaatagg
    29941 attaaaaatc aagaaaaggt gattttttga aaaggatttt aactacaggg aaaaataagg
    30001 aaaaaaattc ccaaaaatct accgaagtta ataggtaaat tcccaaatta acttgattat
    30061 ataactttca gtt
//
LOCUS       DAVBEM010000025        29757 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVBEM010000025 DAVBEM010000000
VERSION     DAVBEM010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29757
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.025"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            132..494
                     /locus_tag="VQ548_001126"
     CDS             132..494
                     /locus_tag="VQ548_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653985.1"
                     /translation="MRLASESRQILDKLKDDVYNKLGYEVSYSSIVSQAVREYVPKKE
                     RIDWIKLKETAIPFSSLKQSNNWEYQTSLMLEKDVLILLSELQNFFLDVFQAKRIHRA
                     FCIRLCLRAQFLLSNNDS"
     gene            902..1201
                     /locus_tag="VQ548_001127"
     CDS             902..1201
                     /locus_tag="VQ548_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653986.1"
                     /translation="MNRNVLNFLRTESAERVSLYIDKANRLEGDVTLLAPSSQDLEDI
                     KNAMFSNPNLELKVARLDVMKKIAYASTRNHYLTGATIFGDISKGTYNCDPKSYV"
     gene            complement(1296..1733)
                     /locus_tag="VQ548_001128"
     CDS             complement(1296..1733)
                     /locus_tag="VQ548_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653987.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISNTYTILSISSFLV"
     gene            complement(1864..2498)
                     /locus_tag="VQ548_001129"
                     /pseudo
     CDS             complement(1864..2498)
                     /locus_tag="VQ548_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
     gene            complement(2708..3358)
                     /locus_tag="VQ548_001130"
     CDS             complement(2708..3358)
                     /locus_tag="VQ548_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HET2653988.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRMHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            3470..4312
                     /locus_tag="VQ548_001131"
     CDS             3470..4312
                     /locus_tag="VQ548_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET2653989.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            4388..4825
                     /locus_tag="VQ548_001132"
     CDS             4388..4825
                     /locus_tag="VQ548_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HET2653990.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKKSKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTDIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            4893..5195
                     /locus_tag="VQ548_001133"
     CDS             4893..5195
                     /locus_tag="VQ548_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653991.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(5286..6359)
                     /locus_tag="VQ548_001134"
     CDS             complement(5286..6359)
                     /locus_tag="VQ548_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HET2653992.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDKLAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHKIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            6515..7192
                     /locus_tag="VQ548_001135"
     CDS             6515..7192
                     /locus_tag="VQ548_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2653993.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            7185..8159
                     /locus_tag="VQ548_001136"
     CDS             7185..8159
                     /locus_tag="VQ548_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET2653994.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVEMQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(8208..10151)
                     /gene="thrS"
                     /locus_tag="VQ548_001137"
     CDS             complement(8208..10151)
                     /gene="thrS"
                     /locus_tag="VQ548_001137"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HET2653995.1"
                     /translation="MINITFPDGAIREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHGDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(10209..10385)
                     /locus_tag="VQ548_001138"
                     /pseudo
     CDS             complement(10209..10385)
                     /locus_tag="VQ548_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
     gene            complement(10392..10532)
                     /locus_tag="VQ548_001139"
     CDS             complement(10392..10532)
                     /locus_tag="VQ548_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HET2653996.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            complement(10963..11163)
                     /locus_tag="VQ548_001140"
     CDS             complement(10963..11163)
                     /locus_tag="VQ548_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2653997.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKGLYINNLL
                     FFTPMVILIVSLLYSYRFRFSL"
     gene            11402..11947
                     /locus_tag="VQ548_001141"
     CDS             11402..11947
                     /locus_tag="VQ548_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HET2653998.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGSGS
                     LYIDETKTTRLLDTPDFPEEFKSLAKAQADELDLLRTKNNLNWAFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKRNKPD"
     gene            12173..12442
                     /gene="rpsO"
                     /locus_tag="VQ548_001142"
     CDS             12173..12442
                     /gene="rpsO"
                     /locus_tag="VQ548_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HET2653999.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            13258..13872
                     /locus_tag="VQ548_001143"
     CDS             13258..13872
                     /locus_tag="VQ548_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HET2654000.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(14164..14913)
                     /locus_tag="VQ548_001144"
     CDS             complement(14164..14913)
                     /locus_tag="VQ548_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HET2654001.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            15046..17382
                     /locus_tag="VQ548_001145"
     CDS             15046..17382
                     /locus_tag="VQ548_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HET2654002.1"
                     /translation="MDKNKIMGLTQREIKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAVASILTSYMA
                     HSEDKNPTAQAIRQRFQGQVVYPMLSNLPFSSDRKWGAMELEGLGIVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            17484..18161
                     /locus_tag="VQ548_001146"
     CDS             17484..18161
                     /locus_tag="VQ548_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HET2654003.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            18148..18945
                     /locus_tag="VQ548_001147"
     CDS             18148..18945
                     /locus_tag="VQ548_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HET2654004.1"
                     /translation="MLASEVIHAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            18962..20065
                     /locus_tag="VQ548_001148"
     CDS             18962..20065
                     /locus_tag="VQ548_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HET2654005.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            20072..20263
                     /locus_tag="VQ548_001149"
     CDS             20072..20263
                     /locus_tag="VQ548_001149"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654006.1"
                     /translation="MKIKEQTRKLAAGYSKHCFEVVDRTDEVSSKHCFEVVDRTDEVS
                     NHTHGKATLTWFELDFRRV"
     gene            20366..21385
                     /gene="galE"
                     /locus_tag="VQ548_001150"
     CDS             20366..21385
                     /gene="galE"
                     /locus_tag="VQ548_001150"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET2654007.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAIEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            21387..22340
                     /locus_tag="VQ548_001151"
     CDS             21387..22340
                     /locus_tag="VQ548_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2654008.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRKLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDDRLKKIEFI"
     gene            22492..23157
                     /locus_tag="VQ548_001152"
     CDS             22492..23157
                     /locus_tag="VQ548_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654009.1"
                     /translation="MLSKEDYTEEIGLIKKQNYVEAELYPIVADIIKPTLKDSLSKRY
                     VFGRQRRGLGQIYYGLSNFPDIVILDKTYENKSRKSIKIEEWKKLRGCVEVKNLNYSL
                     ITEEKIKSTISNSFEHITGEMEQLTGEMGQLIGDLLWYKKVIYTNGIEWRFLSLDDKE
                     EIDNTIVEVVNKRIETEEAGNSFDWWKNIKDLSFNYTDICLSKDCRQEWNEFVKRVKE
                     IEW"
     gene            23196..23297
                     /locus_tag="VQ548_001153"
                     /pseudo
     CDS             23196..23297
                     /locus_tag="VQ548_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group 2 glycosyl transferase"
     gene            complement(23348..23554)
                     /locus_tag="VQ548_001154"
     CDS             complement(23348..23554)
                     /locus_tag="VQ548_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HET2654010.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            23606..24082
                     /locus_tag="VQ548_001155"
     CDS             23606..24082
                     /locus_tag="VQ548_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HET2654011.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            24091..24762
                     /locus_tag="VQ548_001156"
     CDS             24091..24762
                     /locus_tag="VQ548_001156"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HET2654012.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDFETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            24893..25231
                     /locus_tag="VQ548_001157"
     CDS             24893..25231
                     /locus_tag="VQ548_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HET2654013.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            25234..25863
                     /locus_tag="VQ548_001158"
     CDS             25234..25863
                     /locus_tag="VQ548_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HET2654014.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            26103..27254
                     /locus_tag="VQ548_001159"
     CDS             26103..27254
                     /locus_tag="VQ548_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2654015.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            27567..28316
                     /gene="truA"
                     /locus_tag="VQ548_001160"
     CDS             27567..28316
                     /gene="truA"
                     /locus_tag="VQ548_001160"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HET2654016.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFTVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            28306..29079
                     /locus_tag="VQ548_001161"
     CDS             28306..29079
                     /locus_tag="VQ548_001161"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET2654017.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            29057..29518
                     /locus_tag="VQ548_001162"
     CDS             29057..29518
                     /locus_tag="VQ548_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2654018.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT         8718 a         5367 c         6692 g         8980 t
ORIGIN      
        1 taaattttta gattgtggaa tttttttcaa cttaattctt gatttttttt ctaaattgtt
       61 atatacttaa tttacgggat aacagaatcc cgtcagaaag gggtgataat atgggaaaag
      121 agaatgttag aatgcgttta gcgtctgaat ccagacagat attagataag cttaaagatg
      181 atgtttacaa taaattaggc tatgaagtaa gctattccag tattgttagt caagctgtta
      241 gagaatacgt tcctaaaaaa gaacgtatag attggataaa attaaaagag acagctatac
      301 ctttttcatc gttaaaacag agcaataatt gggagtacca gacatcactt atgttagaga
      361 aagatgtatt aatcttactg tctgaactac aaaatttttt cttagatgtc ttccaagcga
      421 aacgtataca tagggcattt tgtatacgtc tatgtttgag agcgcaattt ttattaagta
      481 ataatgattc ttaatactat caatattaat gcggagtgta atgctccgca aaaataaaac
      541 ctattacggg ataaaaacac tactttattt aggatggaaa taagaacgta ttttttacta
      601 atattgttta gaaaggagtt tctttatgac accagaagaa caaactgctt tggaatactt
      661 ttatgaggaa ctcgagagtt acggtgaaga tgagcaagga gaggtctttg atttgtatga
      721 taattaaatc atctccatag tttctgagaa taattgagaa actatactct aaatcatagg
      781 tttatgtaaa gctagatata cacaaaagga ggtacgaatg aagatgaaag ctagagcttc
      841 accgttgaat tgattttgtt tctagaaaaa atcaataatt agaaaaatac gaggtaaaaa
      901 aatgaataga aatgtactaa attttctgcg aacagaaagt gctgaaagag ttagtcttta
      961 tatagacaag gctaatagat tggagggcga tgtaactcta ctcgcaccta gttctcaaga
     1021 tttggaagat attaaaaatg ctatgttttc caatcctaat ctcgagctaa aagtagcgag
     1081 actggatgtg atgaagaaaa tagcatatgc ttctacaaga aatcattatt taacaggggc
     1141 tacgattttt ggggatattt cgaaaggaac atacaattgt gatcctaaaa gttatgtcta
     1201 atataaggga ggttaatccc tccccttgtt tttgaaaatc gaaaggaaaa gtataaaaat
     1261 gaaagttaat gaatatttct ggagaacgag ctgtcttata ctaaaaaaga agaaatcgat
     1321 aaaatagtat acgtgttaga gatgtgtttg tcgtaaaagt ctggatagtt ttctcttagg
     1381 tagtcagctg tcatataata aaaagtagaa tggcaagcag tgatgattgg cataagagat
     1441 gaaaaacgct gagaactaat gaaggctaag agaacaaaaa atagaaaatc aatggtgaga
     1501 acccctaaat agtagaagcg aatcttttta ttgatttgag gataaatctc agcgaattga
     1561 tgtttgagtc ggacgaccaa gagaaatagc aggagtcctt gagcaaggaa gaaaattaaa
     1621 ccagagagca agagccactc aaaagatgtc tcgagtctag tgataaaaaa tgcaaatagt
     1681 agcaaatcaa taactgcaat tgctataaaa tggattctat agagtttttt catgacaaga
     1741 cctccctctt ttatctaact tcattctact ctaaaagaat gggagttaca actaaaatga
     1801 taaaaatagc agaggggaga ttctcttaag ttggctagta ttctttattt gagtttcctt
     1861 ctattatcta acttcttcat cattccagac aaataaagct ccgattgcat tgaggatata
     1921 aaagatgtat ttaccgatat tggcgaagtt tccttgaata ccagcttttg tcagctgaac
     1981 gaaattgtaa atcaaccaaa agccccactg tccctcattg ccaatgcatt caaagcattg
     2041 gcaatgaggg acagtgcaaa ggcaatagtt gttacgtagg caaggagatt catcttgccc
     2101 ccatatccga tatagttggt cacaaaggca aagaggaagg cgatgatgga aatgatgatg
     2161 gccgccaatt ttacctgttt ttggctcatt tggttgggtc tgccttcttg cgaagctttc
     2221 catttcttta tagcaaaggt ataaatgagg aaggtgacgg gataggtaat gatggccgcc
     2281 ttatttccaa ggatataatc aatagcaccg gacaaaatgg tattaacaat accaaagtaa
     2341 ttttcccatt tgcttaattt ccccgtgaaa cgagtggaca acatggaaat cccaacgttg
     2401 gttacggaaa tcaatccaaa gggtacaaga gctgtccatg gtccccagtc tacaaattta
     2461 tcgaggcgtg agttgaggta accagatgca atcgcaatcc aacgaccaaa gcaaccccga
     2521 agaggtcaaa ctatttagat gtagcaaaaa tttttagtga ttttttcata ggttaaacta
     2581 cctttctttt tttcaaatat tctcccattt tttttcaaat attctaccac caaatgaaag
     2641 taaaataaaa tgatagaaat aaaaccctga aaataaaact ttcagggttg gtaggggact
     2701 tgagaaatta gttgattttc tcgacataga gttgttttgc aatgtccata ttcacttgta
     2761 aatcctcgtc gttactgagg atagtgaagg tattgctgaa gccatcaaac tgcttaactt
     2821 ggagctggtc accgatgtga agtgagtgct tgtccagata atggagaatg tcaaaactat
     2881 cgtgcatccg agtcaggcgg taggcgccag cttccttgat atcagctagt gggaggttat
     2941 tgatttcaac gaggagttct cccttggcag gaatagttcc tccgtggggg caggttttag
     3001 ggaaacctag cagtttatct agtctttcca cgaacaggtc agagacagtg tgttccaaga
     3061 cctcagcttc ctcgtgaatc tggtcacttg tatagtctaa atgatgaact agaaaaactt
     3121 caatcaagcg gtgcttacga tagagctcag agaccagttt gagaccgagg tcagtcagta
     3181 gatagccaca ttccttgtcc tttaggatga gattttcact tttcattcgt ttgatcattt
     3241 cagttacggc agggggagag acttgcatgc gagccgcaat ttccttgttg gtaatcttat
     3301 gcaggtctat gccaatttca taaatacatt ttagatagtc ttctttgttt ggggtcattc
     3361 gtttcctctt gtctaatatc tttatctagt atatcaaaaa aagctagatt tctctagctg
     3421 tgacttttta tgttatactt attgcaagag aaaaaacgag gagatggata tgacgaaaat
     3481 agctcttctt tcagatattc atggaaatac caccgccttg gaggctgttt tggcagatgc
     3541 tcggcagcta ggagtggatg aatactggct tttgggagat attctcatgc cagggacagg
     3601 gcgtagaagg attttggact tgttggatca actaccgatt acggctagag ttttgggaaa
     3661 ctgggaagac agtctttggc atggtgtccg taaggaattg gatagtactc gccctagtca
     3721 acgctatctc ttgcgccagt gccagtatgt tttagaggaa atttccctag aagaaattga
     3781 agtgctccac aatcaacctc ttcaaattca tcgtcagttt ggggatttga cagtgggaat
     3841 tagccatcat ctgcctgata agaactgggg gcgagagttg attcatactg gcaaacaaga
     3901 ggaatttgac cgcttggtga ctcatcctcc ctgtgatatt gctgtttatg gacacattca
     3961 ccagcagttg cttcgttacg ggactggtgg gcaattgatt gtcaatccgg gttcgattgg
     4021 ccaacctttc tttttggacg ctcagctacg gaaggacttg cgggcccagt atatgatttt
     4081 ggagtttgat gacaagggcc tggtagatat ggacttccga cgggtagatt acgatgtggc
     4141 agctgaattg cagctggcta aagacctgag acttccctat tttgaggttt actatgaaag
     4201 tctggtcaat gggatccacc atactcatca tcaggaattt ttgagagaat tggctcagaa
     4261 agagggttgc gatcgggagt tagacgactg gttgaaaagt ggtaacgatt gacattacaa
     4321 ctaaaaaggg tataataata gaaaaagaag agtagaggca gggtagcctc gtaaaaagga
     4381 gaagaggatg caaattccaa gtagatttac cattgcgact catatgctga taatcattgc
     4441 cctcgagggg aagaaaagca aggtgaccag tgattttctg gctgctagtg tcggggtcaa
     4501 tcctgtcatt atcagaaaga tcttgtccca gttgaagaag gcagagctga tttcagtagc
     4561 gcgtggaacg ggcggaacag atattgtcaa ggaccttaag gatattagtc ttttagatgt
     4621 ttatcaggcg gtcgaatgtc ttggtaagac aggtcaactc ttcagtttcc atgacaatcc
     4681 gaatccaaat tgccctgtag gagctcatat tcatgatgtt ttggatcaaa aattggagag
     4741 aattcagttg actatggagg cagaacttgg tcaaaccagt ctagaaaaag tcgtggccga
     4801 tgcagagagt cagatgaagg attaagaggg ataaatgccc tcttttttct ttggataatt
     4861 atgataaaat gtagctatta aaggagtaag aaatgtatct cgttatagga attgtattag
     4921 cctttatagt gtcattttgg aaggataata gaagtttgtg gaatccagta ttatttttat
     4981 tatccctcat ttcaagttat ttttatctat cctacctttt ttataaaaat ggatacgaga
     5041 atgttcagtt agctttttat gtatttgcct ttgtcttact tccttttttg ctttttctaa
     5101 gtggcatctt tttaatctat aatggggtca ttttgttgaa gcgagaggga cgttccaagc
     5161 cccattatct ctcaatgctc tttgattttt attgactatt agattctatt taaaaagact
     5221 tagaatgcac atgaaagtat gtattctagg tcttttgttt tgtatacatt taattttcaa
     5281 gagtattatc tatttttcca tgcctggtaa cgagtatcaa tcaataactg ggtaaggcga
     5341 cccaaggttt ctctttcttc tggagtgagg gattgagctt ggacaaagag atgatgaatg
     5401 tattcaagcg cctttaagga agccaagtca ttgatagagc taataccagc ctcaagaata
     5461 gtgccaaaga agaggtcgaa gtagagctga agttcttcgt cagggactgt ggccacccat
     5521 tctttaaagg ttgtgtctac ttgctggcta tcactgttgg tcttatccag ttggacgaag
     5581 tgcttgtcct caatctgcca actaaaggta tcgtgctggg cgatgccacc cagggcagta
     5641 ctctgaacga tgattttgtg agcaggaatt tccagcatca taccgataat ggaaccttgt
     5701 ggaatgaata tcttgcttct atccattatc ctttgataac ccgcagtctg tgtcaattct
     5761 tgatggagac caggtgcatc aaatgtataa actgctgtga tctgattttg caaactttgc
     5821 tcaatttggc tagcagcata gatagcgaga tttcctccct tggaatgccc agctagaata
     5881 accttttgct taggatgatg ggcaaaaaag ttctttaaat agcgaagggc gtgcttttga
     5941 gcaggaattt ccttcatata ggtcaggtgg aaatcttcct tccagccaat gatactgtca
     6001 tctgtcccac gaaagacaat cagataggta tcgaggctga cacgataagt catagccgca
     6061 aattgctttt gcagttcagg gtcgatgtcg ttgataaaat gggagagttt gcaatttttg
     6121 aagcgcttgt gttgagccaa tttatctaat aattgaaggc gatttttgct agtaagcatg
     6181 gtgggctctc ttggaacctg aggtgctaga tctaaaagac gttgaggaag tgtggagacc
     6241 agattatcaa aggagaggta ggtgatttct attaaggtta gaatgtctaa ctcattcaag
     6301 ggaaggtcgt aataagaatc atatgcgaca tctttcagat agtcaaaaat attggccata
     6361 agagctcctt tctttttatt tatcttagca aatttccctc aaattagcta gtagcatagc
     6421 ctgtttgcac tggctaaaaa caggctattt caaattcagt ttcagaccat ctagcatgga
     6481 aaaatctgtt ataataatgg aaaaggagaa gcgcatgcac aagattttat taatagaaga
     6541 tgatcaggtc attcgtcaac agattgggaa aatgctctct gaatggggat ttgaagtggt
     6601 cctggtagaa gactttatgg aagttttgag tctatttgtt cagtcggaac ctcatctggt
     6661 cctcatggat attggtttgc ccttgtttaa tggttatcac tggtgtcagg aaatccgcaa
     6721 gatttccaag gtacctatca tgtttctttc ttcgagagac caggctatgg atattgtcat
     6781 ggcaatcaat atgggggcgg atgactttgt gaccaagcct tttgaccagc aggttctttt
     6841 agctaaggtt cagggcttgt tgcgtcgttc ctatgagttt gggcgtgatg agagtttgct
     6901 ggaatatgct ggtgttatcc tcaataccaa atccatggat ttacattatc aagggcaagt
     6961 cttgaatttg accaagaatg aattccagat tttacgcgtg ttatttgagc atgcaggcaa
     7021 catcgtagca cgtgacgacc tgatgcggga actttggaac agtgactttt tcattgatga
     7081 taataccctc tctgtcaatg tggctcgttt gcgtaaaaag ttggaggagc agggattggt
     7141 aggatttatc gagaccaaga aaggaatagg gtacggattg aagcatgctt gattggaaac
     7201 aattttttct agcctatctg cgctcccgta gtcgtctttt tatctatctg ctttctttgg
     7261 catttcttgt cttactcttt cagtttttat ttgccagtct aggaatttac ttcctctact
     7321 ttttcttctt gtgttgcttt gtaaccatct tatttttcac ttgggacata ttggtggaaa
     7381 tgcaggtcta tcgccaggaa cttctctatg gagagaggga agccaagtct cctttggaaa
     7441 tagctttagc agaaaaatta gaagcgcgtg agatggaact ctatcagcag aggtcaaaag
     7501 cagaaagaaa actgacggat ttgctggatt actatacctt gtgggtccat cagataaaga
     7561 cccccattgc agccagtcaa ctcttagttg cagaagtggt cgaccgccaa ctgaagcagc
     7621 agctagaaca ggaaattttc aaaatcgact cttataccaa cctagtttta cagtacctgc
     7681 gtttagaaag tttccatgat gatttgctct taaagcaggt tcaaattgag gacttggtca
     7741 aggaaataat tcgtaaatat gctcttttct ttattcaaaa aggcttaaat gtcaatctac
     7801 atgaccttga taaagaaatc gtgacggata aaaagtggct gctagtggtt attgagcaaa
     7861 tcatctcaaa cagtctcaag tacaccaagg aaggtggtct ggagatttat atggatgacc
     7921 aagagctttg tatcaaagat acgggaatcg ggataaaaaa cagtgatgtc ctccgagtat
     7981 ttgaacgtgg cttttcagga tacaatggcc gtttgaccca gcagtcctct ggacttggcc
     8041 tttatctatc taagaaaatt tctgaagaac tggggcacca gattcgtatc gagtctgagg
     8101 tcggaaaagg aacgacagtg cggattcagt ttgctcaagt gaacttagtc cttgagtaaa
     8161 aatagatgag aaaaagcctc cagattggag gcttttatgc tagactctta tttctcaacg
     8221 cgtgatttgt tggcgatatc agctaggata gcttgaacaa aattatcaac tgagacagtt
     8281 tgtgtttctt tttggccgta gcgacgaacg ttgactgttt cgtcttccat ttctttgtct
     8341 ccaacaatta attggtaagg aatcttgctg gtttgtgaag cacggatctt gaactgcatt
     8401 ttttcattgc gctcatctac gtctgcacgg acaccgcggt cacggagttt cttggctact
     8461 tcccaagcgt agtccacgtg tttttcgtta gatactggga tgagggttac ttggtgtggt
     8521 gccagccatg ttgggaaggc ccccttgtag ttctcaatca agatagctgt gaagcgttcc
     8581 atagttgaga taaccccacg gtggatcatg actggacggt gatcttcgcc atcagctccg
     8641 atgtatttga ggtcgaagcg ttctggcaac aagaaatcaa gttggatagt agaaagggtt
     8701 tcttcttttc caagggcagt tttaatctgg atatccaatt ttggtccgta gaaggctgct
     8761 tcaccttcgg cttcaaagta gtccacgccc atttcatcaa gagctgcacg aagcatggtt
     8821 tgggcatttt cccacatctc atcgttatca aagtacttat gagtatcttg agggtcacga
     8881 agagagaggc ggaagcggta gtcagtcaag ttgaagtctt cataaacatc gataatcaac
     8941 tgaagggcac gttggaattc ttcttggatt tgttctggag taacgaatag gtgaccgtcg
     9001 ttgagtgaca tttcacgtac acgttgaagg ccagtgaggg caccagattt ttcgtaacgg
     9061 tgcatcatac cgatttcagc gatacggatt ggcaattcac ggtaagagtg aacatggtgt
     9121 ttgaaaactt ggatgtggtg cggacagttc attggacgaa ggacaaattc ttccccgtca
     9181 cccatgtcca tggttgggaa catgtcttct tggtaatgat cccagtgacc agaagtcttg
     9241 taaagctcaa cagaagcaag tggtggagtg tagacgtgtt ggtagccaga agccaactct
     9301 ttgtttacga tgtagcgttc caattcacga cggatagtcg caccatttgg caaccagaat
     9361 ggcaaacctt gtcccacttc ttgtgaaatc ataaagaggt caagctcttt accaagttta
     9421 cggtggtcac gttccttagc ttcttcacgc atttgaaggt agtttttcaa gtctttcttg
     9481 tcaaaccaag ctgtaccgta gatacgttgc atcatagcgt tgtcgctgtt tccacgccag
     9541 tacgcaccag ctacatggag aaggtggaag atttggatac gacctgttga tggaacgtga
     9601 ggtccacggc agaggtctac atattcaccc tgacgataga tagtcaaacc gccttcgtct
     9661 tctgagtgtt cttcaatcaa ttccaacttg taagggtcat ttttgaagat ttcacgtgcc
     9721 tcgtctttag tcacttcttc acgaatagat gggaagtttt ctttgacgat tttttgcatt
     9781 tcttcttcga tacgaggaag gtcttcgtta gagatttgac cagctgtgtt gtcagtatcg
     9841 tagtagaaac catcttcgat ggctggacca actcccaagt gaatgtctgg gaaaagacga
     9901 cgagctgctt gggcgaacaa gtgagctgct gagtgacgca agattggaag ggcatctccg
     9961 tgatcaggtg tcacaatttc gatgcttcca tcttcagtga tagcgcgagt agtgtcgatg
    10021 agtttgccgt tgaatttacc agccaaggct tttttagcta gggaattgct gatagattgg
    10081 gcaatttcaa aagttgttac gccagattcg aattcacgaa tagcgccatc tgggaaagta
    10141 atgttaatca tgatgttctc cttttttatt atttcatagt ttctaagcat tgatttttta
    10201 tcagcagact acttccaagt tctaacgttc aattgctttt ctttatcaga gaggaagttt
    10261 tccatttccg tcagaatatc tatatccaaa cgttgagaaa gttctaatag tcaccagata
    10321 ttttctgaaa gtttttgttc cagtgtgtag ggtgtttcat catagtagcg tccttgcttt
    10381 gtcatcacca gtcattggaa atttccaata tcattagata aagccaagag gtcttcttct
    10441 accgtccact tgaaatcatg atgcttaact tccagttcgt gataagcttg tcggattgcc
    10501 caactgcgct ccactaattc ttgcaactcc ataattagta tcctaataaa aaaatgcgac
    10561 atcctcgaaa ggacgtcgca acgtggttcc accttcattt atgtacctca aaagagaggg
    10621 acacctctga tcggctctaa cgtggccacc gttttatgtt ttcataaaaa actcaagagt
    10681 agtatcagtt tagacttcct atgcgtttcc agcaaccacg cactctctag tagaaaggga
    10741 ctaagtgact tgtctctatg gattattata gcatgattgt gagatttttc aaggattttg
    10801 tgaaagtttt ttgtttttca ttttttgtag aatatgcttg atgctaatac cagaatccat
    10861 gcccaccaga gcaactgttt catagattag caagtaaatt agtataaaca caccaaaggt
    10921 tatgatagta aagtaaaaga gcagtccgtt accaactaac catcaaagtg agaaacggaa
    10981 acggtagcta tagagtaacg atacaatcaa gattaccata ggtgtaaaga agagaagatt
    11041 gtttatatag agtcccttga gtgtaagggg gtcagaaaca actagcaaga acaactcata
    11101 aagtggccaa taaaagaata atatgaccag atagtagggg agatgggaat agaatctacg
    11161 catgataatc acctcgtttt aaaaaaacag acaacttaga tctcttgcta tgattattat
    11221 agtatgttta aaacaagaaa gtaaatttgt tgacaaagaa gatttttctt ttcactagaa
    11281 tcatggttag ttttcttggt agaaatattt tgataataat taagcaagac tattgacatt
    11341 gattattaag agtgtcacaa ttgttgtaac taaaataatt acaacaagag gggtataaaa
    11401 aatgaaacta gcagttattg cagcaaatgg acaagcgggg aaggcaattg ttgaagaagc
    11461 agtcaaacga ggacatgaag taacggctat tgttcgttct gaaaacaaaa gtcaagctga
    11521 gtctattatt aaaaaagatt tatttgagtt gacaaaagat gatcttactg gatttgatgc
    11581 tgttatttca gcgtttggtg cttatacacc agatacgcta ccgctccaca gcaaatcaat
    11641 cgaactattt aatcagcttc ttgctggaac acagacacgt tttctagttg tagggggatc
    11701 aggaagcctt tatatagatg aaacaaaaac gacacgactt ttagatacgc ctgattttcc
    11761 tgaagaattt aagtcactag caaaagctca agcggatgaa ttggatcttc ttcgtacaaa
    11821 aaataatctc aactgggctt ttgtcagtcc tgctgtagat tttattcccg atggtgaaaa
    11881 aacaggaaac tacattctag caggagaaat ttttactact aatgaaaaaa ggaataagcc
    11941 agattagtta tgcagattat gctattggat tggtagatga acttgaaaaa ggtcatcata
    12001 taaaagaacg tatctcttta cttgaaaaat aataactatg agagtattaa tgtttgacag
    12061 aaaatttaaa tcttggtaga atagggattg tcgtaaagac aaataacttc ttcttggtta
    12121 caggcatgcc aacctgtcac tcggatgaag ccaaataaaa aggagaaaca tcatggcaat
    12181 ctcaaaagag aaaaaaaatg aaatcatcgc acaatatgca cgtcacgaag gtgatacagg
    12241 ttcagtagag gttcaagttg ctgtccttac ttgggaaatc aaccacctta atgaacacat
    12301 caaacaacac aaaaaagacc acgctactta ccgtggattg atgaaaaaaa tcggtcgccg
    12361 tcgtaacttg cttgcatact tgcgtaaaaa cgacgttaac cgttaccgtg agttgatcaa
    12421 ctctctagga cttcgtcgct aattcaagat acaaaggctg tcaaaagcac aaagtaaaaa
    12481 taggaaaatt tacgaagaaa cttcagtttc taggagattt tatctttttt gccaagtgct
    12541 taggccgtgt tcaattgagc atatcttgat aatgaagcta ctctaaattg ggtagctttt
    12601 ttgtgttgtc accttacctc gatatactca agtataatct ttggttacgg ttcctagcac
    12661 tgtaaggtaa aataaaccag cttttctccc ttcggggaga ttttttttgt ttcactgaaa
    12721 gtttcgtacg atcttcgcct cgtcgcctag tctataaacg atttatctag caagaatcat
    12781 gatgctaagg gcgtcaaaaa tccgtatgaa aatagggaaa tgacacagtg ttcgatgagc
    12841 acaaggagtt tcatcttttt cactaggatt ttagcccgga ctcaaatcag ctctctgact
    12901 tcagagggct tttttattga ggttttatcg gtaacaattt tggagactac aaaaacctca
    12961 aacggtatca gctaattaca ccataaaggt gcgcagttac tcggcttttc aagccgagta
    13021 gttgtatgca agccccctag aagagcccac tctttacaaa gtaaagtata gtatgttata
    13081 ctttacatgg aagtagtcac tgaattccag ttagaaatta ctttgtaact acgttttgag
    13141 gaggagtaaa atgctttcct acgttcgata ttacccacta gcgatagcta aattaatgtg
    13201 tctgtgctct cctaaaatct gctgatttat tactgactaa tacaggagtt tttttttatg
    13261 ggacagacaa tcatatctgc tattggtgtt tatatttcca ccagtatcga ttatttaatt
    13321 attttaatta ttttatttgc acagctatca cagaataaac agaaatggca tatttatgcg
    13381 gggcaatatc taggcacagg cttacttgta ggggcgagtt tagttgctgc ttatgtcgtt
    13441 aatttcgtgc ctgaagaatg gatggttgga ttgcttggtt taatccctat ctatttaggg
    13501 attcgctttg caattgttgg agaagatgcg gaagaagaag aggaagaaat tattgaaaga
    13561 ttagaacaaa gcaaggcaaa tcaactgttt tggacagtta cattgctgac aattgcgtct
    13621 ggcggagata atttaggtat ctatatacct tattttgctt cgttagattg gtcacagacc
    13681 ctcgtggcct tgcttgtgtt tgtaatcggc ataattatct tttgcgagat tagtcgggtg
    13741 ttatcttcta ttccgttaat attcgagaca attgaaaaat acgagcgaat cattgtgccc
    13801 ttagtattca ttctacttgg actatacatc atgtatgaaa atggcacgat agagactttt
    13861 ctgatcgtgt agattttttt gtttcactag gattttagtc cgagctcaaa tcagctctct
    13921 gattttcaga gggctttttc attgagtata aatggacaat cttaaagtta ctctattgta
    13981 gagtggcttt tgatttgatt aggagattct tataaatata gtaaaatgaa ataagaatag
    14041 gacaaatcga tcaggacagt caaatcgatt tctaaaaatg ttttagaagt agaggtgtac
    14101 tattctagtt tcaatttgat atataaatga aaaccttagc tgtttggcca aggttcattt
    14161 cttctatgca agttcttctc ttttcttatc tgggttccag atgaagcttg cgataaagct
    14221 aaagatgatg gttaggatag cgagaataat agcaaggatg agggcaggga tgcggataaa
    14281 ccaccagagt ggatttggtt ttttatcatt gtgccattgt ttcgtttctt cgtccagacg
    14341 ttggaattct gtttgaatac gattggcgac tgtttcaatg ccttcatcat tcattttctt
    14401 gatatctgag atatcgattg gatttccaaa gttcatatcg acacgttcac ggctaatcaa
    14461 gcccttcaaa gtcatgggac cggtgtaggt aaccggcatg atacggacct tggccatttt
    14521 ggcaatcagt gctgcgcccc ccttgacatc gtttgagtgg cggctaccac ttggaaacat
    14581 gatgagagag cggtcacttt ttttgagaac gttgatagga tatttgatgg ctgaggcgct
    14641 gggattttca cggtcgatgg gaaaggcgcc acacatacga atccaccaac caaagatacg
    14701 gttggtaaag agttcttttt ttgccataaa gatgaactgt tttggcttgg tcgcaaaggc
    14761 catataaaca ggatcccacc aggtacggtg aggcgcaact aaaatataat tttcatcttg
    14821 attaggaatt ttatcagtat tatgatagtg agcattgcca ttgatggacc ataagagcaa
    14881 tacaactaat ccacgcaaat aagtataaaa catgcgatct ccttcgattg ttttcttgtt
    14941 attattatac cttatcaaag gagggctggc aaacttttcc cttgactaga tgcatatttg
    15001 ggatgaaatt agaattctgt taaaaaaaat gatataatag aatttatgga taaaaataag
    15061 attatgggat taacccaaag agaaatcaag gaaagacagg ctgagggttt ggtcaatgac
    15121 tttaccgcat cagccagtac cagcacttgg caaatcgtta aacgaaatgt ctttaccctt
    15181 tttaacgctt tgaactttgc cattgctttg gcccttgcct ttgtgcaggc ttggagcaat
    15241 ctggtcttct ttgctgttat ctgctttaac gctttttctg ggattgtgac cgagctacga
    15301 gccaaacaca tggtggacaa gctcaatctc atgaccaagg aaaaggtcaa aaccatccgt
    15361 gatggtcagg aagttgctct taatcctgaa gaattagtgc taggagatgt cattcgtttg
    15421 tctgcaggag agcagattcc tagtgatgcc ttggttttgg aaggctttgc ggaagtcaat
    15481 gaagccatgt taacgggaga aagtgatttg gtgcaaaagg aagttgacgg cttacttttg
    15541 tcaggaagtt tcctagccag tgggtcagtt ttatctcaag ttcaccatgt cggtgcagac
    15601 aactatgctg ccaaactcat gcttgaggct aagaccgtta aacccatcaa ctcccgtatc
    15661 atgaaatcgc tggacaagtt ggctggtttt actgggaaga ttatcattcc ctttggtctg
    15721 gctctcttgc tggaagcctt gcttttaaaa ggcctgcctc tcaagtcatc cgttgtaaac
    15781 tcgtcgacag ctcttttggg aatgttgcct aagggaattg cccttttgac cattacttcg
    15841 ctcttgactg cagtgattaa gttgggcttg aaaaaggtct tggtgcagga gatgtactct
    15901 gttgagacct tggcgcgcgt ggatatgctc tgtctggaca agacgggtac catcacccaa
    15961 ggaaagatgc aggtggaggc tgttcttcca ctgacggaaa cttatggtga agaggctgtt
    16021 gccagcatcc tgaccagcta tatggcccat agtgaggata aaaatccaac agctcaagcc
    16081 attcgccaga gattccaagg tcaagtagtc tatcctatgc tctctaatct tcccttctcc
    16141 agcgaccgca agtggggagc catggagtta gaaggtttgg gaatagtttt cttaggggca
    16201 cctgagatgt tgctggattc tgaggtccca gaagccagag aggccttgga gagaggatca
    16261 cgtgtcttgg tcttagctct cagtcaggag aaattagacc atcacaaacc acagaaacca
    16321 tctgatattc aggctctagc cttgctggaa atcttggatc ctattcgaga gggagcggca
    16381 gagacgctga actatctccg ttctcaggaa gtggggctca agattatctc tggtgacaat
    16441 ccagttacgg tatccagcat tgcccagaag gctggttttg cggactatca cagctatgtc
    16501 gattgttcaa aaatcacgga tgaggaattg attgctctgg cggaggagac agcgattttc
    16561 ggacgtgttt cccctcatca aaagaaactc attatccaaa cgctgaaaaa agcgggtcat
    16621 acaacagcta tgactgggga tggagttaat gatatcctgg ctcttcgtga ggcggattgt
    16681 tctatcgtaa tggcggaggg agacccggca acccgtcaga ttgccaacct ggttctcttg
    16741 aactcagact ttaatgatgt tcctgagatt ctttttgaag gtcgtcgtgt ggtcaataac
    16801 attgcccaca tcgctccgat tttcttgata aagaccatct attccttcct gttagcagtc
    16861 atctgtattg ccagtgcttt actaggtcgg tcagagtgga ttttgatttt ccccttcatt
    16921 ccgatccaga ttaccatgat tgaccagttt gtggaaggtt tcccaccatt cgttctgact
    16981 tttgagcgaa atatcaaacc tgttgagcca aatttcctca gaaaatccat gcttcgtgcc
    17041 ctaccaagtg ccctcatggt cgtgtttagc gttctttttg tgaaaatctt tggaacgagt
    17101 caaggttggt ctgagttaga aatctcaact ctcctctatt atctcttggg gtcaattggt
    17161 ttcttatccg tatttagagc ctgcatgcca ttcactctat ggcgagtcct cttgattgtc
    17221 tggtcagtag gaggcttcct agccacagct ctcttcccaa gaatccaaaa actgcttgaa
    17281 atttcaacct tgacagaaca aacgttgcct gtttatggtg tcatgatgtt ggtctttaca
    17341 gtgattttca tcctgactag tcgctatcaa gctagaaaat aaagaaagac tgcaatctgt
    17401 ggattgcagt ttttttaggt acaagattgc cagccgaaat gtggtataat aagaggtaat
    17461 agagttttgg aaagtgagag aagatgattt caaagagatt agaattggta gcttcctttg
    17521 tgtcacaggg ggctatttta ctagatgtgg gaagtgacca tgcttatctg cctatcgagt
    17581 tggttgagag aggccaaatc aaaagcgcta ttgcaggtga ggtggtggaa ggtccctatc
    17641 agtctgcggt taaaaatgtt gaggctcacg gcctaaagga gaaaatccaa gtccgtttag
    17701 ccaatggctt ggcagctttt gaagagactg accaagtgtc tgtcattacc attgctggca
    17761 tgggtggtcg tttgattgct aggattttag aagaaggttt ggggaagtta gctaatgtag
    17821 agcgtttgat cctccagccc aataatcgtg aagacgactt gcgtatctgg ctacaggatc
    17881 atggattcca gattgtagca gaaagcatct tagaagaagc tggaaagttt tatgagattt
    17941 tggtggtgga agcaggacaa atgaagctat cagccagtga tgttcgcttt ggtcccttct
    18001 tgtccaaaga agtcagtcca gtatttgtcc aaaaatggca aaaagaagct gagaagctag
    18061 agttcgctct cggacaaatc ccagaaaaaa atctggaaga acgtcaagtt ctagtagata
    18121 agattcaagc tatcaaggag gtgctccatg ttagcaagtg aagtgattca tgcttatgaa
    18181 gccttttgcc ctcaggaatt ttctatggag ggagacagcc gtggtctgca aattggcact
    18241 ttagacaagg gtatccaaag ggtcatggtt gccctcgata ttcgtgaaga gacagtggca
    18301 gaggccattg aaaagggtgt ggacttgatt atcgtcaagc acgcgcctat ctttcgtcct
    18361 atcaaggact tgcttgccag ccgtccgcaa aatcagattt acatcgacct gattaagcat
    18421 gacatcgcag tttatgtcag ccataccaat attgatatcg ttgaaaatgg gctcaatgac
    18481 tggttttgtc agatgctagg aatcgaggag acgacttatc tgcaggaaac aggtccagaa
    18541 cgtggaattg gacgtattgg gaatattcag cctcagacat tttgggaatt ggcccaacag
    18601 gtcaagcaag tctttgacct agatagcctt cgaatggtgc attatcaaga gaatgatttg
    18661 cagaagccta tttcaagagt agcaatttgt ggtggaagcg ggcagtcttt ctataaggat
    18721 gctttggcaa agggggcaga tgtctatatc actggtgata tctactacca tactgctcag
    18781 gatatgctgt ctgatggctt gttagcattg gatccaggtc actatatcga agtgcttttt
    18841 gtggaaaaaa tcgcagcact ccttactcaa tggaaagaga aaaaaggctg ggaactagag
    18901 attttaccta gtcaagcatc gaccaatcct ttccgtcata tctagttaga aagtgaagac
    18961 aatgaaaaaa gttgccatta ttggagcagg aattgtggga gcaacagctg cctactacct
    19021 ctcgagagaa agtgacctag aggtgaccgt ttttgaccat gagcaaggtc aagccaccaa
    19081 ggccgcagca ggaattatca gtccttggtt ttccaaacgc cgtaataaag cctggtacaa
    19141 gatggcgcgc ttgggggctg atttttatgt ggatttatta gctgatttag agaaatcagg
    19201 acaaaaaatc gacttttacc agcgttcggg agtctttctc ttgaaaaagg atgaatccaa
    19261 gttggaagaa ctttatcaac tggccctcca gcgcagagaa gaatctccct tgatagggca
    19321 attagccatt ctggaccaag cctcagctaa tgaattattc cctggtttgc agggatttga
    19381 ccgcctgctc tatgcttctg gtggagcgag agtagatggc caactcttgg taactcgtct
    19441 gctagaagcc agtcatgtca agctggtcaa agaaaaagtg actctgacac cgttagcatc
    19501 aggctaccag attggtgaag aggagtttga gcaggttatt ttggcgacgg gagcttggtt
    19561 gggggacatg ttagaaccct tgggttatga agtagatgtt cgtcctcaaa aaggacaact
    19621 acgagattat cagctggtcc aagacatgga agcttaccct gttgtcatgc cagaagggga
    19681 gtgggatttg attccttttg caggtgggaa attgtcctta ggcgctaccc acgaaaatga
    19741 catgggattt gatttgacgg tagatgaaac cttgctccaa caaatggagg aggccacctt
    19801 gactcactat ctgattttgg ctgaagctac ttcaaaatct gagcgtgttg gaatccgtgc
    19861 ctacaccagt gatttctctc ctttctttgg gcaggtgcct gacttaactg gtgtctatgc
    19921 agccagtgga ctaggttcat caggcctcac aactggtcct attattggtt accatttagc
    19981 tcaactgatc caagacaagg agttgacctt ggaccctgaa aactacccaa ttgaaaacta
    20041 tgtcaaacga gtaaaaagcg aataatactc aatgaaaatc aaagaacaaa ctaggaaact
    20101 agccgcgggt tactcaaagc actgctttga ggttgtggat agaactgacg aagtcagctc
    20161 aaaacactgt tttgaggttg tagatagaac tgacgaagtc agtaaccata cccatggcaa
    20221 ggcgacgttg acgtggtttg aattggattt tcgaagagta taagcatttt actgaaattt
    20281 tatcaggtag tttaggatgg caaatgacat tccctgtcaa aaatggtaaa ataagaaaaa
    20341 ataatctgag aatcgaggaa aaaagatgca agaaaagatt ttggtaactg gtggtgccgg
    20401 ttttattgga acccacactg ttattgaatt gatccaagca ggccatcaag ttgttgtggt
    20461 ggataatctt gtcaatagca atcgtaagag tttagaagtt gttgaaagaa tcacaggagt
    20521 tgagattcct ttctatgagg cagatattcg tgacacagct accctcagag atattttcaa
    20581 gcaggaagaa ccgactggtg tcattcactt tgctggtttg aaggctgttg gcgaatcaac
    20641 acgtatccct cttgcctact atgacaacaa tatcgctgga actgtcagcc ttttgaaagc
    20701 catagaagaa aacaactgta aaaacatcat cttcagttct tctgcgacag tttacgggga
    20761 tccgcacaca gtgcccatct tggaagattt cccactttca gtgaccaacc catacggtcg
    20821 tactaagctc atgctagagg aaattttgac tgatatttac aaagcagact cagaatggaa
    20881 tgttgtcttg cttcgttact ttaacccaat cggagcccat gagagtggtg atttgggaga
    20941 aaatccaaac ggtattccaa acaatctctt gccatatgtg actcaagtag ccgttggaaa
    21001 attagagcaa gtgcaagtgt ttggagacga ttacgatacg gaagatggaa caggtgttcg
    21061 tgactatatc cacgttgtcg atttggctaa gggtcacgtt gcagctttga aaaaaatcca
    21121 aaaaggttca ggactaaacg tttataacct tggaactggt aaaggttact cagttcttga
    21181 aattatccaa aacatggaaa aagcggtggg acgtcctatt ccttaccgta tcgtagaacg
    21241 tcgcccaggt gatatcgctg cctgctactc agacccagca aaagctaaag cagaactcgg
    21301 ttgggaagca gaactcgaca tcacccaaat gtgtgaagac gcatggcgtt ggcaaagcaa
    21361 gcatccaaat ggatttgaag actaagatga tgatttcaat catcgtccct tgtttaaacg
    21421 aagaggaagt acttcctctt ttttatcagg ctctggaagc tttacttcca gatttggaaa
    21481 cagaaatcga gtatgtcttt gtcgatgatg gatcaagtga tgggaccttg gaactcttaa
    21541 aggcctatcg ggagcaaaat ccggcagtcc attatatttc tttctctcga aattttggca
    21601 aagaagcagc cctttatgca ggcttgcaat atgcgacagg agatttggtg gtggtgatgg
    21661 atgcagacct ccaagatcct cctagtatgt tgtttgagat gaaaaatgta ctagacaaaa
    21721 atgtagactt ggactgcgtt gggacacgga gaactagtcg ggagggagaa cccttctttc
    21781 gcagtttctg tgctgttctc ttttatcgcc tcatgcaaaa aatcagccca gtggctctgc
    21841 cgtcgggtgt ccgtgatttt cgtatgatga gaaggtctgt agtcgatgcc attttaagct
    21901 tgaccgagtc caatcgtttt tcaaaggggc tcttcgcctg ggtgggtttc aaaacctact
    21961 atttggacta tccaaatgtc gaaaggcagg ctggcaagac cagttggagt tttaggaaac
    22021 tctttttcta ctccattgaa gggattatta atttttcaga ttttcccttg attatagcct
    22081 ttgtagctgg tctcctatct tgttttcttt ctctgctgat gacctttttt gttgtggttc
    22141 ggaccctcat tttgggcaat ccgacatctg gttggacctc tctgatggct gttattctct
    22201 ttcttggagg cattcaactc ttgaccattg ggattctcgg caagtatatc agtaagattt
    22261 atttagagac taaaaaaaga ccactttatc ttatcaaaga aaaaagtgat gataggctaa
    22321 aaaagataga atttatctga catagtcact ttttgttatt tgtaattctt ttagttcgga
    22381 gtttgggtga tttttaaaag aattagggat ttgaaatgat ttaaaaaatc tatgtagact
    22441 aaatttaaat tgtagtgact taataaataa aaaatttagg agtattatgt tatgctaagt
    22501 aaagaggatt atactgaaga aatcgggcta ataaagaaac aaaattatgt agaggctgaa
    22561 ttgtatccta tagttgctga tataattaag ccaactttaa aagatagttt atcaaaaaga
    22621 tatgtcttcg gaagacaaag aaggggtttg ggacaaattt attatggtct aagtaatttt
    22681 cctgatatag ttattttaga taagacttat gaaaacaaat ctaggaaaag tataaaaatt
    22741 gaagaatgga agaaacttcg aggatgcgtg gaagttaaga atttaaatta tagtttaatt
    22801 acagaggaaa aaatcaaatc aaccatatcg aacagttttg aacatataac tggagagatg
    22861 gaacaactaa ctggagagat gggacaactt attggagacc ttttatggta taaaaaagta
    22921 atttatacaa atggaattga atggagattt ctaagtttag atgacaagga agagatagat
    22981 aatacaattg ttgaagtagt taacaaaaga atagaaacag aagaagcggg aaattctttt
    23041 gattggtgga agaatattaa agatttatcg ttcaattata cggatatatg cctatctaaa
    23101 gattgtagac aagagtggaa tgaatttgta aaaagggtaa aggaaataga atggtagaag
    23161 tctattctca ttgagaaatt tagattttaa gttacagtaa gatttattta gagactaaaa
    23221 aaagaccact ttatcttatc aaagaaaaaa gtgaccttcc tgattttaca gaaaaaaata
    23281 aagtgaaaag actataattt tacatggaaa tgtgctaaac tagagggagt ggattatcgc
    23341 cattgattta ggcttcctgg tttccaatca gggcgcgagt tgggcaattt ttaacagcct
    23401 ctaagacatc ctgactagga gaaatttctt tttccagttg gtcagggtca tcgtaaaaac
    23461 gcacgattcc attatcgtgg taatcaaata aatcagaata agtttggcaa agcccacagg
    23521 cgatacatcg ttcaggtata agtgtgattt tcatgttcat atttatattg taataagaaa
    23581 agtaaaaaaa aacaaggagt aaggtatggc aaaagaaccg tggcaagaag atatctatga
    23641 tcaagaagaa tcaagagcag agcgtcggca tcgaaaccac ggaggggctg ataggatggc
    23701 taatcgtatt ttgacgatcc tagctagtat tttctttgta attgtggtgg tgatggtcat
    23761 cgttctcatc tatctatcat cggggggaag taatcgcaca gcagccttaa aagactttca
    23821 tgattctgat gcaagtgtag tacaaatctc atcttcaagc agttctcagc ctgagcagag
    23881 ttcagagcca gaatctactt ctagtagttc agaagaagct gctaatcctg aaggaacgat
    23941 taaagttctc gcaggagaag gggaagcagc tattgccgct cgtgcaggaa tctccattgc
    24001 tcagttagag gccttgaatc ctgggcacat ggctacagga tcttggtttg ctaatccagg
    24061 tgatgttata aaaataaaat aggagccgat atgaaaacaa ttcaaattgc tattgatggt
    24121 cctgcttcca gcggtaagag tacggtcgca aagattattg ctaaggattt tggattcacc
    24181 taccttgata caggagctat gtatcgtgca gcgacctata tggctcttaa gaaccaatta
    24241 ggagttgaag aagtcgaagc ccttctagcc ttgttggacc agcatccaat cagctttgga
    24301 cgttcagaaa ctggagacca gcttgttttt gtaggagatg tggatattac ccatcctatc
    24361 cgtgaaaatg aagtgaccaa tcatgtttct gctattgcag caattcctga agtgcgtgag
    24421 aaactggttt ctctccaaca agaaattgcc cagcaaggcg ggattgtcat ggatggtcgc
    24481 gatattggaa ctgttgtatt gccacaagca gaattgaaaa ttttcctagt agcttctgtt
    24541 gatgagagag cagagcgtcg ttacaaggaa aatattgcca agggaattga aacagacttt
    24601 gaaaccctaa aaaaggaaat tgctgcgcgt gactacaagg atagtcatcg tgagacttct
    24661 cctctcaaac aagcagagga tgctgtctac cttgatacaa ctggtttgaa cattcaagaa
    24721 gtagttgaaa aaatcaaagc agaagctgaa aaaagaatgt aaatgtagaa aagccgatag
    24781 attgatatcg gtttttttct aaatttgtca aaatgctgat tttagggtat aatagttgct
    24841 gttcgagaaa ttttgatttt caaagaatag tgaatgatga taaggagaaa ccatgaacaa
    24901 tttaccaaat tgtccaaaat gtaactcaga gtatgtctac gaagacggtg ccctactggt
    24961 ttgcccagag tgtgctcatg agtggaatcc tgctgaagtt gcagaagtag aagaaggtct
    25021 tgtcgctatc gatgccaacg gaaataaatt ggctgatggt gatacagtaa ctctcatcaa
    25081 ggacttgaaa gtaaaaggtg cgccaaaaga tttgaaacaa gggacgcgcg tgaaaaatat
    25141 ccgcatcgta gaaggcgacc acaatatcga ctgtaagatt gatggttttg gtgccatgaa
    25201 acttaaatca gagtttgtga ggaagattta agcatgtcaa aacactataa acttgtattt
    25261 tatagccgta tcttcttgtt tctagcggct tttacgggag tttatcttga aattactaag
    25321 catggtggtt ttgggatgct tctctattac acggttctgt ccaacctctt ggtaactatt
    25381 tttacccttt atcttctaaa ggttatgagc cgtgtaggtg aaaattggca aaggccaagt
    25441 ctcttgcgct taaaaggtgg ggtcaccatg agtatcatga ttacctgtgt gatttaccat
    25501 ttcctcttgg cgcccattgc gactaatttc tataccctag aaaatttcct ttgccactat
    25561 atcgttccca tctggttttt agcggatacc ctcttttttg acaaacaggg tcaatacaag
    25621 atttgggatc cagcagtgtg gaccatttta ccctttctgt atatgatgtt tgctcttttt
    25681 aatggcttgg ttctaaaact caatattcca aatgccaagg ataatccttt cccttacttc
    25741 tttttgaatg tgaacaaggg ttggaatgtt gtgtttaagt ggtgtctgat tatctttgtt
    25801 gcctatatgg tagcaggatt tattttctac tttatcaagc aaatcaagag aaagtcatcc
    25861 taatactctt cgaaaatctc ttcaaaccac gtcagtttcc atctgcaacc tcaaaacact
    25921 gttttgaaca acctgcggct agcttcctag tttgctcttt gattttcatt gagtataaga
    25981 tacaagggat tcattttcga atttaagaag gagtctacaa accaatgagg cttcttcttt
    26041 tcttgcttat ttgataacta tcaaaaaagt agaagattaa gagaaatata gaaagagatt
    26101 tcatgaaaca atttttagaa cgggccagca ttttggctct ctccctcgtt ttgattacct
    26161 ccttttccat ttcgagtgcc ctaccagcca tgtttgacta ttatcagggt tattctaagg
    26221 aacaaattga gctcttggtg agcttgcctt cctttggaat catgatgatg ttactgctaa
    26281 atggtttctt agaaaaaata tttcctgagc gcttacagat tagtttgggc ttgctgattt
    26341 tatcattgag cggtacagct cccttctggt accaagccta tccctttgtc tttggaacac
    26401 ggcttctctt tggtttgggt cttgggatga tcaatgccaa ggccatttct attatcagtg
    26461 aacgctacca aggaaaaagg cgaattcaga tgttagggct acgcgcttct gcagaggtcg
    26521 ttggagcttc tctcattacc ttggccgtcg gtcagttgtt ggcctttggt tggacagcta
    26581 tctttctagc ctatagtgct ggatttttgg tgctgcccct ttatctgctc tttgtccctt
    26641 atggaaaatc aaagaaagaa gtcaagaaaa gagcgaagga agcaagtcgt ttaactcgag
    26701 aaatgaaagg cttgattttt accttagcta tcgaagcggc agttgtagtt tgtaccaata
    26761 cagctattac catccgtatt ccaagtttga tggtggaaag aggattgggg gatgcccagt
    26821 tatctagttt tgttcttagt atcatgcagt tgatcgggat tgtggctggg gtgagttttt
    26881 ctttcttgat ttctatcttt aaagagaaac tgctcctctg gtctggtatt acctttggct
    26941 tggggcaaat cgtgattgcc ttgtcttcat ccttgtgggt ggtagtagca ggaagtgttc
    27001 tggctggatt tgcctatagt gtagtcttga cgacggtctt tcaacttgtc tctgaacgaa
    27061 ttccagctaa actcctcaat caagcaactt catttgctgt attaggctgt agtttcggag
    27121 cctttacgac cccatttgtt ctaggtgcaa ttggcttact aactcacaat gggatgttgg
    27181 tctttagtat cttaggaggt tggttgattg taatctctat ctttgtcatg tacctacttc
    27241 agaagagagc ttaggattga ttcctaagtt tttcttttga tactcaatga aaatcaaaga
    27301 gcatagttga ttgagtttgg aatagtacgc tgtagctgct aaaatatttc tagaaattaa
    27361 tttgactttt ctaatagagt tattcatatc ttatttcaat ctactataga aagctagccg
    27421 caggttgctc aaaatagtgt tttgaggttg cagatggaaa ctgacgtggt ttgaagagat
    27481 tttcgaagag tatgagattt ttatacccat acaatatttg ttttaggtcc ttgtttacag
    27541 actaatttct tgataaaata gaggttatga cgagatataa agcaactatt tcctatgatg
    27601 gttatgcctt tgctggcttt cagcgccagc ctcatgcgcg tagcgttcag gaagaaattg
    27661 aaaaaacctt gaccagatta aataaagggc aagccattac tgttcacggt gctggtagga
    27721 cagatagtgg ggttcatgcc ctgggacagg tcattcattt tgacctgcct tatcagatgg
    27781 atgaggagaa actccgtttt gccttggata cccagtctcc tgaagatatt gatgtgattt
    27841 cgattgagct tgtggcagat gattttcatt gccgttatgc caagcatagc aagacctatg
    27901 agtttactgt ggatagagga cgtcccaaaa atccgatgcg ccgtcactat gccacccact
    27961 ttccctaccc actcgatgtg gaacgaatgc agattgcaat caaaaagcta gagggaaccc
    28021 atgattttac cggttttaca gcctctggga ctagtgtaga ggataaggtt cgcaccatca
    28081 cagaagctag tttaatagtc gatgagacag gacaattttt gacctttacc ttttcaggaa
    28141 atggtttctt gtataaacag attcgcaata tggtggggac tcttctcaaa atcggtaaca
    28201 accgcatgcc agtagagcag attgatctca tcttggagaa gaaggacagg caacttgcag
    28261 gtcccactgc agcaccaaat ggtttgtatt taaaggagat tcgttatgaa gaataatcgt
    28321 attttagcac tttctggaaa tgatattttt agtggtggtg gactgtcagc tgatttggct
    28381 acctatacct tgaacggctt gcatgggttt gtagcagtga cttgtttgac agccttgaca
    28441 gaaaaaggat ttgaagtctt tccaactgat gataccattt ttcaacatga attagatagc
    28501 ttgcgtgatg tggaatttgg gggaattaag attggtcttc tccctactgt cagtgtggct
    28561 gagaaggcct tggactttat caaacaacgc ccaggagtac ctgtggtgtt ggatcctgtc
    28621 ttggtctgca aggaaacgca tgatgtagct gtcagtgagc tctgccaaga gttgattcgc
    28681 tttttccctt atgtcagtgt gattacgcct aatctcccag aagcagaatt attatccggt
    28741 caggaaatta aaaccttgga agacatgaaa actgcagcgc agaaattgca tgatttagga
    28801 gcgccagcag tcattatcaa gggaggcaat cgtcttagtc aggacaaggc tgtggatgtc
    28861 ttttatgatg gacagacctt tactatccta gaaaatccag ttatccaagg ccaaaatgct
    28921 ggtgcaggtt gtacctttgc ctctagcatt gccagtcact tgattaaagg tgataaactt
    28981 ttgccagcag tagaaagctc taaggctttc gtttatcgtg ctattgcaca agcagatcag
    29041 tatggagtaa gacaatatga agcaaacaaa aacaactaaa atcgcccttg tatccctatt
    29101 aaccgccctt tctgtggttc taggttattt cttaaaaatc ccaacaccta caggaattct
    29161 aactctttta gatgctggtg tcttctttgc ggccttttac tttggtagtc gtgaaggagc
    29221 ggtagtcgga ggactagcaa gtttcttgat tgacctctta tcaggctacc ctcagtggat
    29281 gttctttagc ttggtcaacc atggcttgca gggatttttc gcaggattta aaggaaaaag
    29341 tcagtggtta ggccttattt tagcaactat tgccatggta ggaggctacg ccttgggttc
    29401 tactttgatg aatggctggg cagcagccct cccagaaatt ctaccaaatt tcatgcaaaa
    29461 tatggtaggg atgattgtag gatttattct tagtcaaagt atcaagaaga ttaagtaata
    29521 ctcttcgaaa atctcttcaa accacgtcag cttccatctg caacctcaaa acactgtttt
    29581 gagcagcctg aggctagctt tctagtttgc actttgattt tcattgagta taaagaggtt
    29641 gagtaaaaag tatttcaaat aagaaaaacg catagtatca ggtgttgaat gaactgcccc
    29701 ccaaaaagtt agacagaaaa aatctaactt tttggggtgt ttttattatg aaattaa
//
LOCUS       DAVBEM010000026        28634 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVBEM010000026 DAVBEM010000000
VERSION     DAVBEM010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28634
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.026"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(499..2226)
                     /gene="ezrA"
                     /locus_tag="VQ548_001163"
     CDS             complement(499..2226)
                     /gene="ezrA"
                     /locus_tag="VQ548_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HET2654019.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2308..4254)
                     /gene="gyrB"
                     /locus_tag="VQ548_001164"
     CDS             complement(2308..4254)
                     /gene="gyrB"
                     /locus_tag="VQ548_001164"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HET2654020.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFIPDPKIFTETTTFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4269..4832)
                     /locus_tag="VQ548_001165"
     CDS             complement(4269..4832)
                     /locus_tag="VQ548_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2654021.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKPSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4917..5471)
                     /locus_tag="VQ548_001166"
     CDS             complement(4917..5471)
                     /locus_tag="VQ548_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HET2654022.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5482..6705)
                     /locus_tag="VQ548_001167"
     CDS             complement(5482..6705)
                     /locus_tag="VQ548_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET2654023.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVSLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6742..9192)
                     /locus_tag="VQ548_001168"
     CDS             complement(6742..9192)
                     /locus_tag="VQ548_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HET2654024.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQAMGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIIGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9391..10320)
                     /locus_tag="VQ548_001169"
     CDS             complement(9391..10320)
                     /locus_tag="VQ548_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET2654025.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10460..10747
                     /locus_tag="VQ548_001170"
     CDS             10460..10747
                     /locus_tag="VQ548_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HET2654026.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10781..12115)
                     /gene="ciaH"
                     /locus_tag="VQ548_001171"
     CDS             complement(10781..12115)
                     /gene="ciaH"
                     /locus_tag="VQ548_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HET2654027.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12105..12779)
                     /gene="ciaR"
                     /locus_tag="VQ548_001172"
     CDS             complement(12105..12779)
                     /gene="ciaR"
                     /locus_tag="VQ548_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HET2654028.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12888..15434)
                     /locus_tag="VQ548_001173"
     CDS             complement(12888..15434)
                     /locus_tag="VQ548_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HET2654029.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHIAYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15558..15998)
                     /locus_tag="VQ548_001174"
     CDS             complement(15558..15998)
                     /locus_tag="VQ548_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HET2654030.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15973..16842)
                     /locus_tag="VQ548_001175"
     CDS             complement(15973..16842)
                     /locus_tag="VQ548_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HET2654031.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFTELTNTEANCLVGTKEFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDLESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16884..17612)
                     /locus_tag="VQ548_001176"
     CDS             complement(16884..17612)
                     /locus_tag="VQ548_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2654032.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(17620..18099)
                     /locus_tag="VQ548_001177"
     CDS             complement(17620..18099)
                     /locus_tag="VQ548_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2654033.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVDHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVK"
     gene            complement(18110..18808)
                     /locus_tag="VQ548_001178"
     CDS             complement(18110..18808)
                     /locus_tag="VQ548_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HET2654034.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18801..19067)
                     /locus_tag="VQ548_001179"
     CDS             complement(18801..19067)
                     /locus_tag="VQ548_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HET2654035.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(19133..20059)
                     /locus_tag="VQ548_001180"
     CDS             complement(19133..20059)
                     /locus_tag="VQ548_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HET2654036.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20134..20949)
                     /locus_tag="VQ548_001181"
     CDS             complement(20134..20949)
                     /locus_tag="VQ548_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654037.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20953..21273)
                     /locus_tag="VQ548_001182"
     CDS             complement(20953..21273)
                     /locus_tag="VQ548_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET2654038.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLTKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(21570..21650)
                     /locus_tag="VQ548_001183"
                     /pseudo
     CDS             complement(21570..21650)
                     /locus_tag="VQ548_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(21694..23691)
                     /gene="metG"
                     /locus_tag="VQ548_001184"
     CDS             complement(21694..23691)
                     /gene="metG"
                     /locus_tag="VQ548_001184"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HET2654039.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEYDGKLTLLTVDPAVPNGSVIG"
     gene            complement(23815..25074)
                     /locus_tag="VQ548_001185"
     CDS             complement(23815..25074)
                     /locus_tag="VQ548_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2654040.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKKSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(25076..25777)
                     /locus_tag="VQ548_001186"
     CDS             complement(25076..25777)
                     /locus_tag="VQ548_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2654041.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(25761..26960)
                     /locus_tag="VQ548_001187"
     CDS             complement(25761..26960)
                     /locus_tag="VQ548_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HET2654042.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILIPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            27246..28592
                     /gene="gor"
                     /locus_tag="VQ548_001188"
     CDS             27246..28592
                     /gene="gor"
                     /locus_tag="VQ548_001188"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HET2654043.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
BASE COUNT         8568 a         6299 c         5113 g         8654 t
ORIGIN      
        1 taaatagcga gaaatatcta tcctatcttc tagaatgtct tccaaacgag aaaactctcg
       61 taaacaaaga ggttttagag gcctatttac cgtggactaa agttgtacaa gaaaagtgca
      121 aataagaaat ctccagatta ggaactatcc gtgagttctc tagtctggag atttttcaat
      181 agacttcgtt attggacggt taccaagtta cttcaaagta cagatttgaa gctgcagata
      241 agactgacga aatcacttta atactaaatg aaaatcaaaa agcaaactaa gaagctagcc
      301 tcaggctgta cttgagtacg gtaaggcgac gctgacgtga tttgaagaga ttttcgaaga
      361 gtataaaaca ctgttttgaa gtggtggata aatcggctgg gtaaaaactc aatctcagga
      421 gaaaatgaag taaatctccc cacaactata gaaaaagatt tgattctgct cctcacacaa
      481 taaaatcttt ttcttttatt aaaaacgaat cgtttcacgt gttttctcat atgaggtaac
      541 aaagcgattg gttacaccag gctctgccac ttccaatgct tgagaaatct tgtcaaatga
      601 agcgtgataa tcaaattctt tttcaaaaat atctaaagct tcgttaaatg cttcttgaat
      661 gcgttcatca aatgagcgat agcggttaga atattgcaag agttgctctg tcaaagttgc
      721 atattgtaca atattataag tttccgtttc taaagcttcc atatcattcg ttgcaatttc
      781 aagaactcgg gtaacagatt caatgttaat cattttttgt tctaactcaa ccattaaatc
      841 ctcggtatta ttgcttgccg taaagaataa cttcaagaaa gtttgtggaa tacctggcag
      901 attgcgtttt tccatgtatc gcttgatagt atggagacga ttgacataaa cattggcctt
      961 ttgacgtgca ttaatatcat ctttctcaat ttgtgtcagg cgctcactaa ctgaaatttg
     1021 ctcatcttca atatctttta gttgagtttg taaatcctca agattttctt caagaactga
     1081 ataagcttgg gttggttctt cttgatttga agttacctca acaatagctg cctcaaaact
     1141 ctctaattct gtctgaatac gacgaacatg gcttgcagct gtctcaggaa gtaaataggt
     1201 cttgttcaaa cgtgcaatat cttctcccaa taaagtatta ttctctttca tatgttgaag
     1261 gtaagttgga agagttgcaa gtagattttc cactactttc tgagcagcaa tttctcgagt
     1321 aaaaatatca tacaaggcat tgatttcctc ttgtgcctgt ccattctcat attcggcatt
     1381 atccaattcc aactgacgaa tattctcttg gtttttcttg aatgcttcat aaagcaagtg
     1441 gaaacgcgct tcaatatccg tttcaacaaa atgataatta gcatcaatta gtttacgata
     1501 accggcttcc aaatcctgta attgatctgg caattctgta gaaagcgtcg taaccaaggc
     1561 tggaacacga tccacaatat gacttaaggc caaaatgtga ttttctgtat tatccaaaat
     1621 cactgcggct tccacagggt cacccgatga attcaaggtt acaaattgtg aaaattcaga
     1681 ttggatattt tctaattgtt tttcaatttc atccaaggct tgaccatact gttctgaatt
     1741 ttcagcaact ctatgctgaa gttcctcaaa taaatccaaa gcatgaagaa cacgaccact
     1801 atttttagat tcttgcttct ctaagtctgc caaagcattg cgaattgccg caatatcttc
     1861 ttcaatcaaa gtaatttgac tctcaatttg gtcaatttga tgactggcct tgagaaaacg
     1921 aaatgaatgg ttataacctt ctgcttcaaa gagattattt tcaatatcgg caaaagagtt
     1981 gagagataaa tcgacccatt tttgattcca ttcacggaaa gccacttgac tttgtccaat
     2041 caagtgcata ttttttacag cttctacttc atcatttact ggaagattgt atagttcttc
     2101 ttttctttct tctagcgcct ctaatctccc ctcgtttcgc ttacgtagaa agattgccac
     2161 tacataagcc agaactaaaa tgactgcaat tgcaaccatt aaataaatta gttgtccatt
     2221 agacatatca aactcctttt ttacttgaaa caatcgtaac gattatatca tattttttag
     2281 accaagggaa ctacttctcc ctatttttta gacatcaagt gtactataga cagcattttc
     2341 ttcgataaac tcacgacgag gctctactcg atcccccatc aacatatcaa agattttatc
     2401 tgcttctgca gcatcatcta cagaaactct agccatcaag cgatgttcgg gatccatggt
     2461 tgtttcccac agctgatgat cgtccatttc acctagcccc ttataacgct gaatagtcgg
     2521 tttggtacga ccttcactat aacgggctaa agcttcttgg agtttgattt cttgatctgc
     2581 acccggctgg atatattctt taatctcgct tccaaccttg acaccataga ttggtggttg
     2641 ggcaatataa acataaccag cttctaggat tggtttcata taacgataaa tcaaggttaa
     2701 aagaagggta cgaatatggg ctccatcgac atcggcatcg gtcatcaaaa cgagtttttg
     2761 gtaacgggct ttcgaaacat caaattctgc gccaaatcct gttcccatgg ctgtgaaaag
     2821 actacgaatt tcttcgttag ctagaatctt atccatactt gctttttcaa cgttcaaaat
     2881 cttaccgcga attggaagga tagcctgaaa ctcacggtta cgaccagatt tggctgatcc
     2941 accagctgag tctccttcga cgatgaagag ttctgtttca gcagggttat tagaagaaca
     3001 gtctgctagt ttccctggaa ggttggaaat ttccaaacca gattttttac gtgtgacttc
     3061 acgcgcacgc ttggcagcca cacgagcctt ggcagctaaa atcccttttt ccacgatacg
     3121 tttggcaatc tgtggatttt ccatgaggaa atcggagaag gcttcactga agaggcgatt
     3181 ggtaatcttg accacttcgc tatttcccaa tttggtcttg gtttgtcctt caaactgtgg
     3241 atttgggtgt ttaactgaga taactgcagt taatccttcg cgaacatctt cccctgttaa
     3301 attatcttca ttgtctttca gtaacttatt cttacgagca taatcattga taacacgagt
     3361 cagtgccgta cggaaacctt gttcatgcgt tccaccttca tgggtatgaa tattattggc
     3421 gaaactcatg acattttcat ggtaacctgt tgtgtactgc atggctacct caactgtgat
     3481 atcatccatc tcaccgtctg tatagattgg tgtatcaaag attacatcct tgttctcgtt
     3541 gatatattca acgtaactag caatcccacc ttcataatga taatgcttgg tttgttccaa
     3601 accttggcgc ttatcagtga tagaaatttg aagaccgcga tttagaaagg ccaactcttg
     3661 aatccgttta tttaatttat caaaatcaaa ggttgttgtt tcagtaaaga tttttgggtc
     3721 cggtatgaag tgaaccgttg ttccagttct atctgtatcc ccaaccacct caaggtctgc
     3781 aacaacatga ccacgacggt attcttggta atgaatctta ccgtttttat ggacatgaac
     3841 gtctaattga gtggaaaggg cattaactac tgacgacccc accccgtgaa gaccacctga
     3901 aaccttgtat ccaccaccgc cgaactttcc tccagcatga aggactgtaa agacggtctc
     3961 aacagcagga cggcctgttt tttcctgaat atcgactggg ataccacgcc catcatccac
     4021 aacagtaatc gaatcatctg gctcaataaa aacttgaata tggctggcaa atcctgccaa
     4081 ggcctcgtca attgagttat caacaatttc ccagactaga tggtgaagac cttcttttga
     4141 ggttgatcca atgtacatcc ctggacgcat acgaacagcc tctaagccct ctaaaacttg
     4201 aatttgactg gcatcataat cctgtgcctg cagatttttg atttcttctg tcatcttatt
     4261 cctttttctt atatgtctaa tacttgtctt aaattcacga tactggtaaa caagtgggta
     4321 tcaagtcctg cagcttgacc tgcttcgata tcaatcggcc gatcaccaat gacaagacca
     4381 gagctaatct gatacttttc tcttaaataa agcatggatt cgggatttgg ctttctctta
     4441 aagcctgagc tagaagtcac cacttctgta aaataagctg ctatagaggg tttttctaaa
     4501 atttccaaaa cctgatcatt tcgatgagag accaaaaaat gacggccacc ttgatttaaa
     4561 atgtcttcca ataggtcaga aactccttca aataaaatcg ggtgttcaag ctctctggct
     4621 tcattttcct tgtacttttc taaaaaattc tctaaattgg gagcgaatgt ctcaatcgca
     4681 aaaggagtag aaacctttaa agcttgatag acactgtcat ggtcttgtgt gataccatac
     4741 agtgccaatg tttcaacaaa tgcagctgtt gaagtttcat aattatccag taaagttcca
     4801 cctaaatccc agatgtaatc gtgatatttc atacccttca ttatagcatt tttttatgaa
     4861 aaaagcgatg atttccctga gttttccaca taaaaaacga gagaataact cccgttttac
     4921 tgatttttac caaagacatc tcgatagagc attcctgttc gtaaactctc tgcgtcccct
     4981 cctagttgct ccaccaactc gtaggcaaag gcaagggctg ttgaaggacc ccgactggtt
     5041 gtcaactgac catctaccac tactgtttcc ttgacgtagt gaccatcaag gatttgctct
     5101 tgaacgccgt cataacaagt gtatcgctta tttttcaata tctctgcttg attgagggca
     5161 attggtgccg cacaaatggc tgctagtttc ttcccttctt gctcgaagct ttgcaattct
     5221 tgaatcaagg tctgattatc acgtaaatgt gcagaaccag gcatacctcc aggaagaaca
     5281 atcatatcat agtctgataa atctccatca aagacatgat ctgctcttac ttggattgca
     5341 tgcgaacccg ttacttgctc ttcaaaacca accatatcac atgtgatatt ggctcgacgc
     5401 aagacatcta caactgtcaa ggcttcaatt tcttcaaagc cctgagctaa cataactgct
     5461 acttttacca tgattttctc cttatttaat ttgttttaat acaacctttt tccgtttgaa
     5521 tgggactttt ccgctctttt cttcagctag attagtctgg taactcatcg ataaaagcaa
     5581 accaacacca atcagattac tgataatagc tgatccccct tgcgaaatga aaggcaaggg
     5641 aatccccgtc aaaggaagta gtccagtcac agcaccgata ttctcaaaga tgtggaagag
     5701 caacatcata atcaaacctg tggaaatata agtgtagaac tggttatttg atttaagagt
     5761 aatcttcaac atacggtaaa tcaacatgag atagagggca ataaccagga cagagccaat
     5821 aaagccaaaa tcttctgcaa taaccgtaaa aatcatatct gactctcgaa ctgggataag
     5881 cagattcgaa gcattaaatc cctgaccaaa taagccacca ctcccaatgg caatctgccc
     5941 ttgagcctgc tggtaagtcg ttgtttgggc aaactcaaag ggattgagcc aagccaaaat
     6001 ccgattgatt tggtaggtcg gcattccaat ctggtgaaga aaagctcgtc cgtccttgct
     6061 aataaagata gctaagaaac cagcaactcc tgttacagca gtcacaaata ctgggataat
     6121 aattttccaa gaaacccctg ataataaaac gattcctgag aaaatggcta caaaaaccaa
     6181 agccgtcccc aagtcacttt gaagtgctaa aagaactagg actggaatgg taaagagaat
     6241 catccagaaa attaacaaaa agtccagcga aaccgtgcgt ctccattcct tatgtttctt
     6301 tgtaaattgg acaatgacac gagccaacat gaggatatag gatatcttca taaattctga
     6361 cggttgaaat agggtaattc catttattga tacccagttt ttggcacccg ttgatgcaac
     6421 taagcttgga ttataaaata caatcggcaa gatcataagt cccaagccta aaatatatag
     6481 aaagggggtc accttccaaa gaaattctgt attaaagagc atgaccacaa aaccaatcac
     6541 aagccccaag gcaatccagg cgacctgctg ccctaaaatg ggcagaatat tattgggata
     6601 atcatgacta acggctatat agatagccac cacaccgatg accagtagaa aaaatactgg
     6661 caagagcaaa ctataatcga ctctagagtc gagagaacgt ttcatatata ctaaccttat
     6721 actttcatac aatactattt atcaaagttc attaaaaaat ctatcaatag cctcgtcaac
     6781 ttcggatcga gagatggttt taacagtcgc ttcttctgct agagatgcta ctatttgttt
     6841 gccgtatcgt tttccgatga ttctcctatc caaaataaga gttaaggaac gttggtattc
     6901 acgtctcata cttcttccca aagcctgttt taaacgaata atggccattg gcaattgata
     6961 atcataaaag gcatttttcc cttcttgatt cagttcttga ttaatctttt tcgtcaaggg
     7021 ttcttgagga ttttggaaag gaagcctcgg tacaacttga atcacaaaag gatggcttga
     7081 aaaatcaact ccctcccaga aacttgctgc accaagcaag atttgttgtt cacctttttc
     7141 aaagcgtttc tttagctgat gaacatcccc atttttatac tgggccaagt ggctaactgt
     7201 aagtaaatcc gatactgcta gaagcatgtc tttagcggta aagagaacca aaatcggttg
     7261 ctggaaagct tgaatttcca ctagtaaagc agctacctct ctggcataga cttctaagga
     7321 ggtttctgtt accagaggga aatctttgac cataaccact tcttgttcct gttttccccg
     7381 agattcaatc ttgacaaatt tggcttcagg atagcctaaa aggtctgcca aagaaaccct
     7441 ctgactaatc tcaagagtag ccgatactcc catggcttgg caactctcag gaagtaaaga
     7501 ggacagaaga gtacggcctg attttgtaga agaaatctga attttctttt gactcgtttc
     7561 agttacttca agccagtaat caccttcagc tgtaaaatag cgaaccagct catcaaagcc
     7621 ttctacttct aattctgaaa aatactgatg gagattgtcc agagaatcta agatattttt
     7681 cctagattta ccagactgaa attgttctat caagtagaga cactcaaagc gaatactttc
     7741 tagtatccgt tgttgaaccc tgttttcttc tcctactaaa gccttatcaa ttaaatcgat
     7801 aatagattgt atatcgtagg tctcttgaag cagattttct agagctaaca aaatcttttg
     7861 gacttcatca ataatcagta aacggtcact gacaaattca ggattatctt caagtctggt
     7921 cacgagatag gcatgattag tcactaaaag cttgcaagtc tctgcccttt cttgactacg
     7981 tttccaaaaa tcttccgtca caaataagct ctgggatgat aaattcccat catgacgaag
     8041 gtctgctaga aaatgttggt aacgatagag ttgcccgatt tcatccaaat ctcctgtctc
     8101 tgtctcagta agccagacca agacttgcat tttaaagcgt ctaaataagc gattttcatc
     8161 attttcctgc aaggaatgat aaaaggcatc caacttcaga taattttgtg gtccctttaa
     8221 gctatgaata tctgtatgga acacttcctt gaggcgttta ccttcttctt ccatgatttg
     8281 attttgaaga atctttgtcg gaacactaag aacaatttgt cgctctttgg attgagataa
     8341 agcgggtaag agatagccat aggttttccc aatccctgtc ggcgcttgaa tcagagagac
     8401 aggttcatct ttcaatagca agccaacctc tttagcaaaa ctttcttgtt cctccctcac
     8461 ttcaaggttc aacagagaaa tatttttaga aaagtcttga gatagttttc gtggctccag
     8521 agaagctgcc gttttcttaa aatacagacc ttgaacttgg accaagtctg gagaactcag
     8581 gatagattgg ttgcgataag tttcctcaat aaccaggtag gactcatata ggagagcgtc
     8641 agccatttcc agcaagcgtt ccaagagacc tttaggaagc tgagtcatct tttcccgtaa
     8701 aaaaagaagt aattctgctg tagcttgggc atctgaaagg gctgtgtgtg cgtgtttaag
     8761 aggaattcct aattctcgac acaaaatcgg caagctatat ttttccagtt cagggaaaaa
     8821 gacctgggcc aattcgaccg tatcaacacg agggtttctt agctcatagc cttcaaaaaa
     8881 taaattttcc gccaagagat tagcatcaaa ctgaacatta tgggctacaa aaatcccatc
     8941 ctccaccaag tcaaatattt ttctggcaac ttgcgaaaaa tcaggtgctt gcgccagacg
     9001 ttggtctgtc aatcctgtca gttctttgat atgagcatcc aagggttcat gtggattgac
     9061 atccgtcgta tagtgatcga cgatttctcc gtcctcaatc acgacaattc ccacttggat
     9121 aattttagcc ttactacctg tgctagttgc ctctaaatcc accacaacat agcgattacc
     9181 aatcgttttc attataaaaa attataccaa aaaaagggcc atttggcacc tgcaaacata
     9241 ggataatttt caaactcaag aacactactt ttcttaaaaa tcccatcgaa tagagcattc
     9301 tagcctgctg attttttaaa atagtgaaga aatacgaaaa attgagagaa gaaatgtttt
     9361 catcttcctt ctctcaacga atcatgtatt ttatttaacc atgtcaggat cgtagtcata
     9421 aaatcctgta tcaaggaaac ggtttttagg gtgaagttta cgaacttctt catccagcaa
     9481 gaaggcttgg tcatggctaa agttgccctc ttgaatcaag ctacgcgctt ggataaagag
     9541 ttttgcaatc tcaacaaagt tctgaccagg agtgtagagc ccttctagtt tccagcgagt
     9601 aaagccatgc tccaccaatt ctgttaattt gatcatcaaa tcaaggtcat tgttggcaaa
     9661 gatatgggtc ccatgattat cttcaaaaat ggaatagtgg ctctctggat cacttggctc
     9721 agccaagaag aggtcacgtt tatgcgtctt ttcatcatcg atatgtgtaa agttatagta
     9781 gttttgcaag agtggacgtt tagaatgatg gatgacgcta gcaccgtaaa ccaaaacttc
     9841 agcaggaatt tccaaaatct ctggcatttt gaaaagttca gctgatggaa tttcacgcgc
     9901 caaaacagcc tcagatgcgc cagccttttg tccccagaag ttaatctgac gactgctagt
     9961 taccatggtt gaagcatcgt agatggtctt aaatgaataa ccatcgcggt taactacgta
    10021 aaagacgcct gcatccccaa tcgtaatata gtctgtcttg atttcttcca agaagtctaa
    10081 gaaaggcttg atacggtcca tcatatcttg gtgcatgaga gcattgaccg caacgagcaa
    10141 ttccttacca gcatcatgaa ccaacttagc gatttcacgt aattggtcat aactaaaggt
    10201 cgttggcaga cgaaggccaa aatctttctc accgacatag atacggtcta cgccagcttc
    10261 gagtagttgt tcaacttgtt caatactttc agcagttgct gtaatgacaa tcttttccat
    10321 aagaaaaatt ataccacatt tctccaaaat catccatgct ttgaaaatga aaagggactt
    10381 tattcttttt gtaacctttc tgtaataatt ctctgccgaa aaaatgataa aataggtatg
    10441 tactgttaag gagagaatta tgcccgtaag aaaattacaa tcctatgagg tagactatca
    10501 agaagaatta aaccagcagc ttcctcatta ccaagcttat acacctgaag cgcaatctga
    10561 tgccaatctc aaggaaatcc tattttttat taatatcgct gttttttgta tctgtattgc
    10621 tatctttagt tttatctttt tagcattaaa attatcaact gctcttgcct ttgccgcagc
    10681 aatcggattc agcttacttg ttttaaaagt tcaacggtct attatcaaac gaaaacgtag
    10741 aagataaatc caaaatatcg ccccagttgg agcgatattt ttattttttc tttttagatg
    10801 gtgtctgaat ggcaatcttc acttcaaaga ttgttccctt gggtttatta tctttgacag
    10861 taacagttcc ttttagagca tctacaattt gcttggctag ggataatcct aaaccaaaac
    10921 cacctttttg ccgagttcta gccttgtcta ctcgataaaa acggtcaaaa attttctttt
    10981 tatcttctgt cgaaataccg attccattat cagaaacaag taaataaaga ttgcgatcgg
    11041 tcgccgagat aagaaaatca atttcaccat cctcctcagt atacttgacg gcattatcga
    11101 aaagaatggt catcagttgt ttcagaagaa gctgatctgt gacaattgtt cgatggatac
    11161 gattttcaaa acggaagaca cgattatttt ccgaagcaat catctcgtag tttgtgaaag
    11221 ttgtattaaa aaagctagtt ggaacttctg caagctccgg cttaatccca tcatctctcc
    11281 gagctaagtt cagcaagctt gtcgttaaaa aacgcatatt tcggacttct tccaaactcg
    11341 atgcaatgct ttcgctcaca tccataatgg tagcttctgg cttacgaaaa agggtctcta
    11401 agcgattttg caaaactgcg agtggagttc gtaactcatg actggcattt tccacaaaag
    11461 actgttgctt ctgcatactc tcaagcaggg gcctaacact gaccctagct agatagagac
    11521 tggcaagtaa agacaaaatc cagaaactag ccatcacgac cacaatcaat tgctcatgct
    11581 tttgactagc ctgttccaac tgactggtat taatcaagac agcagcatac ttgatattgg
    11641 ttgaaaccga actaatattg gtctccatca aaatcacacg atagatttct tcctgcccat
    11701 agctattaaa aacctgaatc tggtagatat gtcctagttc tttcttttct aacttaatct
    11761 tatccaagcc caaaaatcga tttccagaaa gaagttgagt aaagtcttta tcaaagagaa
    11821 tgacttccgt attggaactg acattaggtt ttatttctac tttactagcg tccgccctag
    11881 cattttctaa atctttaatc tcttctgttg ccctatttat agccagctga ataactgctt
    11941 gaggattttc actcagtcca tgaagcttat cgtccaccga agtataaaga ctcgaatgca
    12001 tgacttgtaa aataatcaga gtcattgtag aaaaaatcag ggtgaagaca ccgaagttgc
    12061 ggataaaata actaaagtca tccgcatacc atgttttttt aagtttactg aacatctttt
    12121 aaaagatacc caacactacg caaagtttgc aaattctctg caaaagtggt tccctttaat
    12181 ttcttacgga cttttgaaac atagacttcg acaaccgaaa tcgttgtatc actatcaaat
    12241 ccccatagac ggtcaaaaat ctgcgtctta ggcaaaatca cattttgatt ttgaaggaaa
    12301 taaactagta aatcgaactc tttccccagc aattcgacag gagtatcttc aactttaacg
    12361 gtattggttg ataaattaac cacgatattc ccataagtca aggtgttttc attaaacttc
    12421 cctgaacgtt tgagaagggc ctgaatccgc attttaagtt cttctaggta gaaaggtttg
    12481 gtcagataat catccgctcc cagttcaaat ccatgtccct tgtcatccaa actttccttg
    12541 gcagtcataa tcagaactgg tgtcgtaatt cccttttcac gcaattcttt taagacttgg
    12601 aaaccatttt tttctggcaa catcaaatcc agcaaaatca agtcatagac accactctca
    12661 gcttcgtaga gaccttcttc tccatcaaat acctgcataa catccgcaaa atcgtctaaa
    12721 aagtcaaata ctgaatttga cagacctagg tcatcctcaa ccaataagat ttttatcatg
    12781 agaaactcct ccttattaaa actattatac caaatttgcc ttaaaaaaaa ctcaactctc
    12841 tgcattttac atgagatagc tgagttttct ttttatttta ggcttattta tgcatttccg
    12901 tattgaagaa caactgcttc gactgcagct ttttcacggc taatcaagtc aacacgcgct
    12961 gcaatttcct tgattcccat accgatgtta cggctaagag caaggtcaga aagttgcggc
    13021 tcaaagaact ccttgtattc cgccaagcgt tgctgagtct taaatacatg agcaggaagg
    13081 ataacaaagc tatcaaagct catatctcct ccaagggctg ccttaatcca agcccagttt
    13141 tcacgcgccc aagaccaagc tgttttctga gttgcttgat gagctaggaa ttggtaatac
    13201 caagcagaca agtcctgtgg tttgaccaca aatttgtcct tccaagaagt aatcaagttt
    13261 tggatattat ccgcatctgt actgtatgca agagctgctg ccaactggcg tttaaagaca
    13321 gcatctgttg cgtgagtata agtatcaaga taaagtgcta acaagtcttt agtctcatga
    13381 tgtttcatct cattaatcag aacttgtgaa cgaatagctg ctgggagtcc tgcaagattc
    13441 tccttgtgtg ttgcgaagat ttggctagcg acttgactag cttctgcatc atttgagcga
    13501 atcatcatcg aaacagccag ctgacgaacc aattcatcct catctgattc tccgtcttta
    13561 gcttcaaaac caagacggtc atagttatga cgagccaatt tagcaaccag tcctttgaag
    13621 gctgtttcag catccgttcc ttcatcaata aagcgctcaa gggctgaaat cacttgagaa
    13681 acagctgaaa ccaccagata agactcttcc ttagcaagtt tatcaagaac tggaagcaag
    13741 tctgcataag caatgtgccc tgcctcagcc aacaaacgac gttcttgaac aatttgcagt
    13801 ttgcttgtgt tatcaagtgt ctctagctca gcaagaacag cttctaacaa gtctccttga
    13861 tagtcggtaa tatagtgggc agtattttca gtgttgagac gaagagctcc ttcattttca
    13921 gcaagaagag ctgcgtagcc agggatttcg atactttcag tttcgagtgt atcaggcaag
    13981 cctttccagt tgctattgag gggcaccacc cagagacggt tcttgtcttc gttctcaccg
    14041 atgaagaatt gtttttgtga aatcttcaag acatcatttt caactttaac agtaagaact
    14101 gggtaaccag gctgttccaa ccaagaatcc atgaaggctg cgacatcacg tcctgacgct
    14161 tgaccaaggg catcccaaag gtcactacca atggtgttgc tgtattggtg tttttcaaag
    14221 taggcgtgca aacctttagc aaaatcagca tctcctagcc aacggcgaag catgtgcatg
    14281 agacggcttc ctttggcata gacgatagcg ccgtcaaaga gtgtattgat ttcatctgga
    14341 tgtttaactt cgacgtggac agactgaacg ccatcagtag cgtcacgttc aagagcaaga
    14401 ggtactccac ctgtttggaa atcttcaaag atattccagc ttggttcgat ggtatccaca
    14461 cagacgtatt ccatcatatt agcgaaactt tcattgagcc aaaggtcatc ccaccatttc
    14521 atagtcacga ggttcccaaa ccattggtga gccaattcat gggccacaac aagggcaact
    14581 tgttgacggc tagcaaatgt agagttctca tcgacaacca agtaaacttc acggtaggtc
    14641 acaagacccc agttttccat agcaccagct gagaagtcag gaagggcgat gtggagagat
    14701 tgaggaattg ggtacttaac tccatagtaa tcttcgtaaa actcgataga gcgaacagcg
    14761 atatccagtg agaaatcaag atttgaaagt ggatgtgctt tggttgagta gacacctacc
    14821 agggtaccat ttttagtttt agcggtcacc ccttgcaaat caccagcaac aaaggccaac
    14881 aagtaagaag acatgcgagg tgttgtctca aacttccaga tacctgtttc cttacggttt
    14941 tcaacatcga tttctggcat gtttgacaag gccaattcac cttctgcttg gtcaaagcga
    15001 agagagaggt caaaagttgc tttggcttca ggctcatcca cacatgggaa agcttcgcgc
    15061 gcaaaatggc tctcgaactg agtagacaag acctccttct tgactccatc aactgtataa
    15121 taagaagggt aaatccctgt catgttgtct gtaattttac cagaaaaggc aagaaccaat
    15181 tcaacttgac cagcctcagc caattcgata tgaagggctt cattgtcatg gtcaactgta
    15241 aatggacgag cttgacctgc aacttctaca gaggtgattt ccaagtcttt ttggtggagg
    15301 gagatgcggt cactctgtgc ttgaccagtg atggtcactt tcccagaaaa agtcttggtc
    15361 tcacgactca aatctaaaaa taaatcataa tgttcaggaa caaattgctt aataaaatgt
    15421 tcaactgctt gcatagtttt ctcctattct aagtttaaga gctactgctc ttcttcaaac
    15481 aaacttatta tatcatattt tgcttgagaa aaaaggattg gacagcgatt tccaaaactt
    15541 tcttccttct aaatagtcta cagtgggtag accttgcgaa attcttctaa aacaaccttg
    15601 ctttcaggtg taaaagtcag ccctacttca cccaaacagt ctgtgaaaaa gtcctcatga
    15661 acctggcgcc aataggcaag tgatttgtct ccctcacctt ccttaaaggc atgttgcgca
    15721 gaaacttgat tgaagagttc aacagaaacc tttgtaattt cgacaatgca gacagactga
    15781 ttttgactat ctaaaatgac atcgaaggtc cctacttggg gaagtggttc gtcttctagt
    15841 acatagaggt cataggctga tgctgttgct gtcttttctc ctttaaacac caaatccgct
    15901 aaaaggtctg gttcaactcc aaaagcccaa gcatcgattt catctccgat caaaggattg
    15961 atttgcttgt atttattcca catttcttgc ggtatcatgg gtactccttt gtaatttttt
    16021 actttcttct tttatgtgtt taagatgatc tggatggtca atctctaaat caaaaatctc
    16081 tggaatagaa ctgtagtgga taatgcactt gatacccaac tgattcattt tttgtatgaa
    16141 agaagtattc agatagcctg ctacagcaaa attaatcttg ttctttcttg ctttatcctg
    16201 catatctctt agcatatcta acattattgg actttccaga tcatgccatt gactgtttct
    16261 catagtcgca aaaacaaagg aagtcaaatc attcattcca actacaatct ttgaaatgcc
    16321 cgtttccagt atactagata agtcaaaata cgctgacggt aattcaatca tcgttccgac
    16381 tttcccagta aagccatact gacgcaatac tgtaatagct tgttttaatt ggtcggcatc
    16441 attgacaaaa ggaaagataa cagatagatt ggggttggtt tgataaactt ctgtaacgac
    16501 atgtgcttca gcctgaaatt catccaaaca cgccagtaaa cgcctggttc ctctatagcc
    16561 aaacaaggga tgcccttcgt caaaaaactc tttagtcccc actaaacaat tggcttctgt
    16621 attcgttaat tcagtaaaac gataccaaac ttcttcatct gagtacaggg agcagatagt
    16681 ctctagataa tcttttacaa attgctgaca acttgctaat atgatgtttt gattaagctc
    16741 tctcaacaaa tattccccac gaatcatgcc gacgtggtga aatagttgag gataaatttt
    16801 ttcaagaatt ttttcgccac taagggcaag ttgatttctc atagccattc acctcgtctt
    16861 aaaagataca atatcatata taattatatc aaaatttcct ctagttcaaa agcttcataa
    16921 ggttcagata actcatatcc taaaaattct gctacttttt tggaagcctc attatgagca
    16981 tcccaaagtg gaaacatatc tctatttaaa ctctctagaa tcattgcagc accaagcttt
    17041 ttagcaaatc catttccttg ttcgtttggt ctagttgcaa cttccacttc aactgcttta
    17101 cggtaaacta accctgagga aatcccagca atcagttcat tatttttaag aatcacaaag
    17161 ccaaatccac cttttaaaac aaaatcctga taggactcaa aatccccctg taaatcctgt
    17221 gaccattctt ccgtagaaaa gcagttataa atatgattat caataggcac aatattgtaa
    17281 ccttcctcta aatgagtaac tagattattt aaaaattcaa cttgaaaatt tgccttatct
    17341 ttaaaagaat agcgagtaaa agaatttagc cccacttttc gatgcagaaa atcttgccaa
    17401 ttagtatttt ctgaaataat aatcttataa tctaaaccat attttctaac aaaatcttcc
    17461 caaaatctgg aatccaactc ccctgctagg tatagaaaat tcccaacatc ataaaagctt
    17521 gttgtcctat cattgtttcg gtagacagtt ccaatttgag atttaagacc atagagaacc
    17581 atatttttct tccatgtttt aaatagttcc attatccctc tacttcacct tccaattcat
    17641 gtaagaagtc ttgtccagtt ctggaaatcc taataattca gacttaacct tcaagactaa
    17701 tggcgatgca ttttcttctg taatctcttg aatatccatc caaatatatc caagtgaatc
    17761 attcgcacca tcagacacag cttccgaagt cgtaacttga ggtgcactct cattcatttc
    17821 aacatcatac aaggccatga catggtcaac cataaaattt gttaactctt ctctgacgaa
    17881 aacatcgtag attcgaggat tagagtagct tctaacagta aatcccgtct cttccataac
    17941 ttctctagtc agcgtttccg tcagtccttc accaagttgc tgactgcctc caggtagatc
    18001 ataccgatgt tgataagggc ctctcgtttt ttcaatgcag agtaacttcc cattttctaa
    18061 gcaaacagcg tagactccaa agtgtttttt gatttccatc caactcctcc tacttcaaag
    18121 accagccacc atctattgtc aagatttgtc cttgcatggc gctcgctttt ccacttgcta
    18181 aaaaaagact aagctctgct atttcctctg gctcaatcca gcgcttgatt ggagtttcac
    18241 tagccaccca gtcagccaaa ccacctggtt caaaatccgc agcggtcata gctgtcttga
    18301 ctgctcctgg agcgatacca aagacctgaa tcccagcttc agcatagtct agagccaact
    18361 gcttggtgaa gccagccaag gcatgcttgg atgaagtata ggcgtgacca cctccacctg
    18421 ctaggctaga agcaatggaa cacatattga tgatgattcc ctttttattt tccagcattt
    18481 gtgtcaaata ataccgagtc aactctactg gaataatgta gttgatttca aaaatctctt
    18541 gaatgtcctg cgccgtttgt tccaacagtg gtttgtaatc atccaaaact ccagcagtat
    18601 tacacaaaac atccacctga gggcaccagt caaaaatagg ttccaagtcc aaggtcaaat
    18661 ctctctgtaa aaagtgaaaa tcaccctcta agagtggctt ttcaccttgg tcaactccat
    18721 aaacttgata gcccttctct aaaaagaggc gagcttgagc caatccgatc cctgaactca
    18781 ctcctgtaat gagtacacgt ttagtcatgc acttctaccc aatccgttgc caaaacatca
    18841 caaactgtcg ggctccacat ggaaaaacct tctccttcgc cagaaacgtt gattaggaaa
    18901 taaggtgtca tttcaagtgc aagcccattt tgctcgatgg tatcaaagag ttggacatag
    18961 ttttccgcac ctccccaacc agttcgtaca tattttctct tagcctttaa cccaggcagg
    19021 atctcttcaa atgtcatgtt tttctccttt aattctacat tcttcattta attatagcaa
    19081 aaaaccgctt tatacggctt tttgaatgtg agttattcaa acctgctact acttacggca
    19141 aattattccc tgcagcaaga taaatttcat accattcttt tcttgttaag ctaaagtttg
    19201 ccgctcggct aacttctctc aagtgcttag gatttgttgt acctacgact gcctgcattt
    19261 ttgctggata acgcaatatc caagaaatgg caatagttga agaggttact ccatatttaa
    19321 tagctaaacg atcaagtact tgatttaaag cttgaaattt ctcatttcca acaaaattcc
    19381 ctttaaaata cccgaattgt aagacagacc atgcttgaat gaccacatcg tgtaattggc
    19441 aatattcaaa aatgctgcca tctcgcatag ctgcttgact atcttccata ttaacatgaa
    19501 aagctgattc aaatcctgga gtaaaagccg cactcaattg tagctgatta acagctaacg
    19561 gctgcttgac atctttttta agcaactcca tcatcatagg attttgatta gaaactccaa
    19621 aatctcgaac tttaccttgt ttataaagga gattaaaggc ttctgctact tggtcagatt
    19681 ccatcaaagc atctggtcga tgaaggagca agctatctag atgatcaatc ttcaatcttt
    19741 gcaaaatacc gtctactgat tttataatat agtccttaga aaaatcaaaa taggtaaatt
    19801 cttcaatgcg aatgccacat ttggactgaa tccacatctt ttctcttaaa tctggacgat
    19861 tttttaggac aagacctaac agttcttcac aacgaccacg accataaata tcagccaagt
    19921 cgaaggcatt gattccaaca gaaagtgctg tttctacaag ctcttcaact tcttttacag
    19981 acttatcttt tattctcatc attccgagaa caatttctga taattctttg tcatcttgac
    20041 caagagttat gtatctcatc aaatttttct cctttaattt ctaacattct tcccttcatt
    20101 ataacaaaaa accgctttgc aacggctttt tgactatact tcactccatt ttatcttctt
    20161 aaacccacgg aacaagacaa agattccaat aaagaggaca gctaaaggaa taacttttgt
    20221 aaggaaaaca tttgaaattc ccatccactc ataataacgg agcagagaac ccaccacaag
    20281 atgggcaata atcatactga caaatggacg aaagaccgct tctttccaat tccaaatacc
    20341 gataactagc gaaatcgtaa agacagacaa actatcccag ggagccggaa tataaaaggc
    20401 tccttcttgt atgaagcttg ccattcctac atatcctaaa acaactagaa gaactatagt
    20461 cccaacaaca atgtaagtgc caattttcat tttaggagaa tcttggacta aacttcttcg
    20521 taaaattgtg gccacaagtc caaatccaat cagaaaaata agaagttgcc ctaaaaatgt
    20581 gagcaaattg actgttaaga gaggaccttt agaaaaatca cttagtagtt gataataacg
    20641 taatacagcc aggacaagaa ttggcgtcaa aagggactct ttgatagaac tgcgaggtgc
    20701 tcccttgaga atctctttca ttattttttt aggattctta cctagataat cctctgcact
    20761 catgccatct cgttctgctt ctgagaaatc tagcatcatc aaatagatct gctctctgag
    20821 atagtcttca tcatagagaa atccagcaag attaaaactt tcccacaact cctcaaaata
    20881 cttttgattc tcctcagaaa actcatgtag caaagcgctt gtttcttcgt aatacttcat
    20941 tttcttcatg gtttaacccc cattcttaat cccttctact ttttgactca aatcgtccca
    21001 ttgctgccaa aagactgaga cacgctcttc tccttctttc gttaatgaaa aatacttccg
    21061 atctggacca tctggcgacg ggcgcatgtc gcctcttatc cattgatttt tttctaactt
    21121 ttgcaacaaa ggataaatag ttcctggaac gatagtatca aatccagcct ctcgcaaagt
    21181 ctgaaccaac tcataaccat accgctcttt ttgaccaatc atatccaaga cacaaccttc
    21241 aagaacacct tttaatagct gagtttcttt catcacttct cccttctaat ctattttgta
    21301 atacctacta gtaacttcac ctatagtata ttacttctac actagtttgt aaagcataat
    21361 agttaatact cttcgaaaat ctcttcaaac cacgtcagcg tcgccctacc gtatgtatgg
    21421 ttactgactt cgtcagtttc atctacaacc tcaaaacagt gttttgagct gacttcgtca
    21481 gtttcatcta caacctcaaa acagtgtttt gagctgactt cgtcagtttc atctacaacc
    21541 tcaaaaacat gttttgagct gacttcgtca gttctatcta caacctcaaa acagtgtttt
    21601 gagcaacctg cggctagctt cctagtttgc tctttgattt tcattgagta taaataaaaa
    21661 aacagaacta gtctgaacta gtcctgtcta cttttaccca atcacacttc catttggtac
    21721 agctggatca actgtgagaa gggttaattt gccatcatat tcagctgata gaatcatacc
    21781 ctggctgaca tattttttca tcattttacg tggtttgagg ttagcaacga tttgaacttt
    21841 cttgccgacc aattcttgtt catttggata gtattttgca attcctgaaa gaatctgacg
    21901 atcttctcca tcaccagcat ccaagcggaa ttgaagcaac ttatctgaac cttctacttt
    21961 agacacttct ttgacttctg cgacacggat ttcaaccttg tcaaagtctt caaacttgat
    22021 ttcatccttg tttagtttga gctcaacttc gtccggattc cattcttttt cgactgctgg
    22081 tttattgcct tccatttgtt ccttgatata ggcgatttct tcttccatat ttagacgtgg
    22141 aaagataggt gttcctttgg caactacagt cacatctgct gggaagtcag ccaaactcaa
    22201 gttttcaaga ctagaaactt cttccaaacc aagttgagtc aaaactgcac gactagtttc
    22261 catcataaat ggttcaatca agtgagcaac tacacgaatg ctggctgcca agtggctcat
    22321 gacacttgcc aattggtcac gaagagcttc atccttggcc aagacccatg gtgcggtctc
    22381 atcgatgtat ttattggtac gagagatcag agtccagact gcttcaagcg cacgtggata
    22441 gtcaactgct tccatgtgtg tatggaagtc tgcgattgat tgttctgcaa cctcagcaag
    22501 aacatgatca aattcagtca caccttctac ataggcaggg atttgtccat caaagtactt
    22561 attaatcatg gaaaccgtac ggttaaggag gttcccaagg tcattagcca attcatagtt
    22621 gatacggccg acatagtctt caggagtaaa ggttccgtct gaaccaactg gaaggttacg
    22681 catgaggtag taacgaagtg gatctagtcc ataacgctct accaacattt cagggtaaac
    22741 gacattccct tttgacttag acatttttcc gtctttcatg acaaaccaac catgggcaat
    22801 caaacgatca ggtaatttaa catccaacat cataagaagg attggccagt agatagagtg
    22861 gaagcgaagg atatcttttc ctaccatatg gaagactgtt ccattccaga acttgtcaaa
    22921 gttaccatgt tcgtcttgag cgtagccaag agctgtcgca tagttaagaa gggcatcaat
    22981 ccaaacgtag acaacgtgtt ttggatttga tgggacaggc actccccatg taaaggttgt
    23041 acgagatacc gccaaatctt ccaagcctgg ctcgatgaag ttgcgtagca tttcattaag
    23101 gcgaccatct ggcgtgataa attcaggatg agctttgaaa aattcgacca aacggtcttg
    23161 gtatttgcta aggcgaagga agtatgattc ttcagaaacc cattcaacct catgacctga
    23221 tggagcaata ccaccagtca catttccagc ttcatcacgg aaaacttctg ccagctggct
    23281 ttctgtaaag aattcttcgt ctgatactga ataccaacca gagtattcac ccaagtagat
    23341 atcatcttga gcaagtaagc gttcaaagac ctgtgcgaca actttttcat ggtagtcatc
    23401 ggttgtacgg ataaatttat cgtatgagat atctagtaat tgccagagtt ctttaactcc
    23461 aaccgccatt ccatcaacat aggcttgagg tgtaatacca gcttcttccg ctttctgctg
    23521 gattttctga ccatgttcat caagacctgt cagataaaat acatcgtagc ccatcaggcg
    23581 tttgtaacgt gctaggacat cacatgcgat agttgtgtag gcagaaccga tatgaagttt
    23641 cccagatgga tagtaaatcg gcgttgtaat ataaaaattt ttttcagaca taatttttcc
    23701 tttccaggca aatgaaacct gtttttctaa cacttcatta tatcacattt ttaatgaatt
    23761 tcgataggga aatccataca aaaacaagat agacgagtgt ccatcttgtt gatctcattc
    23821 ataacgaagg gcttcaattg gatcaagttt cgatgccttg ttggctggca agactccaaa
    23881 aatcatacca acactagccg aaactgcaag actaaatagg gcaactggga ttgatactcc
    23941 aacttctata ccttctatta aaccttgcag taacaaacct gctaaggcag ttaaaccact
    24001 tgcaattgtc aagccaatta agccacctaa caaggtcaaa atcatggatt caatcaaaaa
    24061 ctgaattaaa atattggcac gtgttgcacc caaagcttta cgaagaccaa tctcacgagt
    24121 gcgctctgtc accgaaacca gcatgatgtt catgacacca gttcctccaa caaagagaga
    24181 aatccctgcg atggaactaa taatcgtcgt cataaaacta aacgattgtt gaatttctgc
    24241 aaatacaacg gactcatctg ccacctggta ttctccctgt tgtaagcctg caagctctgt
    24301 catttttcgt gccagttctg gacccagagt tggggttaaa ctggtatcat tcactcgaaa
    24361 gacaatacta gctatttcat ctatattaaa attcgcagca agggagatat tggtagtaat
    24421 aggcaagcca ccaaacccat atatttttga ctttttagcc tccggactag tataaacccc
    24481 aatgacccgg taactaaatc cattgacttc tacaaccttg ttaatagcct cttgaggaga
    24541 ttcaaataaa ctaatggaca attcctcatc tagcaaaata acacttgcaa actctttgaa
    24601 atcttgctct ctcagactac gacctgcaat aatttcattc ttaacagcgt ccatgtaagt
    24661 tctgtttcca cctgtcaaat tagcattctc aaccttttta tcttgatagg tcaagatggc
    24721 attcgttgaa ttggttacat agtaactatc cactcccttc agtttagctg cctcttgaac
    24781 ccaggattct tgcggttttg gcggttcaac aggaacttcc tcttcctttc cagaaaccgt
    24841 aaaagctgat tgtttctgag taaaagaccc atctttactt tttttaggag agaaaaagac
    24901 gctaatattt ttctgagatt tagtcatatc tttattgact tgacgagata gggaatcacc
    24961 caaagccata atcacaacaa ctgatgaaac accgataata atcccaatca tagtaagcaa
    25021 agaacgcatc ttgtgagcca tgatagatga aaaggcaaat ttcagattct gcatcttagt
    25081 tttcctcctt tcctaactga gcactgtcag acgaaatgac cccatcccga atgacaatct
    25141 gacgtttggc ataggcagca atctcaggct catgcgttac catgataatg gtttttcctt
    25201 ctttattcaa atcaaccaat aattgcataa tttggttacc tgttttggta tccaaggctc
    25261 ctgtcggttc atccgctagg ataatagaag gattgtttac caaggcacgc gcaatggcta
    25321 cacgttgctt ttgaccacca gataattctg aaggtaaatg gtgactacgt tctgtcaatt
    25381 caaccttgtc taaatattcc tcagccaact tgcgacgttt tgaagacgaa actcctgcgt
    25441 aaatcaaggg caattctaca ttttgcagag cattgagctt cgatagaaga aagaactgct
    25501 gaaagacaaa accgatttgt tggttacgga ccttagctag ttgtttttca ccaagcccag
    25561 ccacttcttg accttcaaga taatattctc cactggttgg tgtatccaac atgccaatcg
    25621 tattcatcag agtggactta ccagacccag atggtcccat gatggctaca aattcaccct
    25681 cattcacttc tagattgata tttttgagaa cctgcagttc ttggtcacca ttacggtaac
    25741 ttctgaagat attttttaga ctaattagtt gcttcatcag ccttcacctc ttttccttct
    25801 tccaaggaag atgttggatt actgatgacc ttagcaccgt tcgttaaacc agaagtgatt
    25861 tcttgatttt ctgcgtcagc atttcccaat gaaacctcaa cttttttagc cttttgttgt
    25921 tcatccacaa tccagacata atttttacta tcatccatta ctagactgct aacaggaata
    25981 agaatagcct tagttttgct tttaacctca atgttgacag aaaaaccttg tttcaaatca
    26041 ccaacctcgc ctgtcacatc aatagtataa gggtatttag aacctgtatt attcccggct
    26101 gctggactag ctgcttcacc attgttttta ggatagtcag aaatatagct taatttccca
    26161 gtccattttt tatcaggata cactttagaa gtaaagctta cttcttgacc tacagaaagg
    26221 ttggctagat tgtactcaga caattctccc ttgacttgta aattttcatt gctgacaata
    26281 tgaaccataa cttgactcgc ccctgttgga gatttagaaa cattgctatt gacttcgact
    26341 acagttccct ctagggtact gagaacagtt gttgcatcca attgactttg agccttgctt
    26401 aattgcgctg cagcatctgc acgcgcatca cgggcatcac ccaattgagc atcaatagaa
    26461 gcaacagaat ttccagccac tggagttggg ctttgcaccg ttgcatcttc tcctcctact
    26521 ggcgctggta actgtggagc ctgagctgaa gcggcttcat ttcgtgcttg attgagttca
    26581 ttgatatgac gatctgcctt agctactgct cgactagctg aatcataggc cgcctgcgct
    26641 tctgaactac tgtacttgac taaagcctgc ccttcgctga ccttatcgcc cacagaaaca
    26701 aggatttcat ctaaatcacc cttactagca tcaaaataaa catattgttc attttttgct
    26761 gttactgtcc ctgacaataa aacagaggat gccacgcttc cttccttggc aacaacaaga
    26821 tgagtaggct catcttttac agcagtctga gaaggttgtc taaaaagtaa aatccccccg
    26881 gcacccaata caactacact cgcagcaccg attgctgcat acagttgcca ctttttagct
    26941 ttaccattct ttttcttcat aatgaaactc cttttctttt ttacaatact ttgctattat
    27001 accaaatttc cctccagcaa acaatgcagt tcagatggaa ataatggcag ttcaggatta
    27061 aacaatcgtt cggaattttg cttttctatt gtactagata tataatacac tatcttgact
    27121 tatttggcaa gcttttttgc aattttttgt gcgtagcaga tttttgcaat caaatcaaaa
    27181 aaagaataaa atataactat caaaaaagac actctactat ttaaaagatt acaaaggagt
    27241 tttcaatgag agaatatgat atcattgcta tcggtggagg tagcggagga atcgctacca
    27301 tgaaccgtgc tggtgaacat ggagccaaag cagccgttat tgaggaaaag aaattaggtg
    27361 gaacctgtgt caacgtcggt tgtgttccta aaaaaatcat gtggtacggg gcgcaaatcg
    27421 ctgagacttt ccatcaattt ggagaagact acggctttaa gactactgat cttaactttg
    27481 actttgcaac cctacgtcgc aatcgtgaag cctacattga tcgcgctcgt tcttcttatg
    27541 atggtagttt taaacgcaac ggtgtagact tgattgaagg tcatgctgaa tttgtagatt
    27601 ctcatactgt aagcgtaaat ggtgaactga ttcgtgctaa acatatcgtg attgctacag
    27661 gtgcccatcc aagtattcct aatattcctg gtgctgagct aggtggctct tctgatgatg
    27721 tatttgcctg ggaagaactt ccagagtcaa ttgccattct aggcgctggt tatatcgccg
    27781 ttgaattagc tggcgtactc cacacttttg gtgtcaagac agatctcttt gttcgccgcg
    27841 atcgtccttt acgtggtttt gattcctaca tcgttgaagg tttggtcaag gaaatggaaa
    27901 gaacaaactt accacttcac actcacaaag tccctgtcaa gttagaaaaa actactgacg
    27961 gcattaccat tcatttcgaa gatggtacta gtcacacagc tagccaagtt atctgggcta
    28021 caggtcgccg tccaaacgtt aagggcttgc aacttgaaaa agctggagtg actctgaacg
    28081 aacgtggctt tatccaagtg gatgaatacc aaaatactgt tgttgaggga atctatgctc
    28141 taggtgatgt aacgggcgag aaagaactga ctccagttgc aatcaaggcc ggacgtaccc
    28201 tatctgaacg tctctttaac ggaaaaacta ctgcaaaaat ggattactca actattccaa
    28261 ctgttgtctt ttcacaccct gctatcggaa ctgttggttt gacagaagag caagctatta
    28321 aagaatacgg tcaagaccaa atcaaggttt ataaatcaag ctttgcatct atgtactctg
    28381 cttgcactcg caaccgtcaa gaatcccgtt tcaaactcat aacagctggt tcagaagaaa
    28441 aagttgtcgg acttcatgga attggctacg gcgttgatga aatgattcag ggatttgccg
    28501 ttgctatcaa aatgggagca accaaggctg actttgatgc aactgtggca attcacccaa
    28561 ctgcatctga agaatttgta accatgcgtt aatcgaaaca aaagaagctg atataaatat
    28621 gtctgcttct tttt
//
LOCUS       DAVBEM010000027        28411 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVBEM010000027 DAVBEM010000000
VERSION     DAVBEM010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28411
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.027"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            380..1333
                     /locus_tag="VQ548_001189"
     CDS             380..1333
                     /locus_tag="VQ548_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2654044.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLISLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            1384..2574
                     /locus_tag="VQ548_001190"
     CDS             1384..2574
                     /locus_tag="VQ548_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HET2654045.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGTDAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            2723..3094
                     /gene="rnpA"
                     /locus_tag="VQ548_001191"
     CDS             2723..3094
                     /gene="rnpA"
                     /locus_tag="VQ548_001191"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HET2654046.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            3069..3893
                     /locus_tag="VQ548_001192"
     CDS             3069..3893
                     /locus_tag="VQ548_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET2654047.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAKIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            3912..4898
                     /locus_tag="VQ548_001193"
     CDS             3912..4898
                     /locus_tag="VQ548_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HET2654048.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            4949..5572
                     /locus_tag="VQ548_001194"
     CDS             4949..5572
                     /locus_tag="VQ548_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HET2654049.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPGWQLQQTSQWMNQAQRLRPHFWVYLQRDEQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            5703..7160
                     /locus_tag="VQ548_001195"
     CDS             5703..7160
                     /locus_tag="VQ548_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2654050.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            7183..7464
                     /locus_tag="VQ548_001196"
     CDS             7183..7464
                     /locus_tag="VQ548_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2654051.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            7541..8026
                     /locus_tag="VQ548_001197"
     CDS             7541..8026
                     /locus_tag="VQ548_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2654052.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            8043..8708
                     /locus_tag="VQ548_001198"
     CDS             8043..8708
                     /locus_tag="VQ548_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HET2654053.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            8712..9575
                     /locus_tag="VQ548_001199"
     CDS             8712..9575
                     /locus_tag="VQ548_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HET2654054.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SRGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            9577..10281
                     /locus_tag="VQ548_001200"
     CDS             9577..10281
                     /locus_tag="VQ548_001200"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HET2654055.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            10460..12133
                     /locus_tag="VQ548_001201"
     CDS             10460..12133
                     /locus_tag="VQ548_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET2654056.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            12245..13336
                     /gene="ulaG"
                     /locus_tag="VQ548_001202"
     CDS             12245..13336
                     /gene="ulaG"
                     /locus_tag="VQ548_001202"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HET2654057.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            13450..15426
                     /gene="tkt"
                     /locus_tag="VQ548_001203"
     CDS             13450..15426
                     /gene="tkt"
                     /locus_tag="VQ548_001203"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET2654058.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVTDYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            15543..15842
                     /gene="yajC"
                     /locus_tag="VQ548_001204"
     CDS             15543..15842
                     /gene="yajC"
                     /locus_tag="VQ548_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET2654059.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVEGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            15889..16317
                     /locus_tag="VQ548_001205"
     CDS             15889..16317
                     /locus_tag="VQ548_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HET2654060.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            16319..16729
                     /locus_tag="VQ548_001206"
     CDS             16319..16729
                     /locus_tag="VQ548_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654061.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            17029..19680
                     /gene="adhE"
                     /locus_tag="VQ548_001207"
                     /gene_synonym="adhC"
     CDS             17029..19680
                     /gene="adhE"
                     /locus_tag="VQ548_001207"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HET2654062.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITEPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(20665..20973)
                     /locus_tag="VQ548_001208"
     CDS             complement(20665..20973)
                     /locus_tag="VQ548_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2654063.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(20970..21278)
                     /locus_tag="VQ548_001209"
     CDS             complement(20970..21278)
                     /locus_tag="VQ548_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2654064.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(21283..22578)
                     /locus_tag="VQ548_001210"
     CDS             complement(21283..22578)
                     /locus_tag="VQ548_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2654065.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPSAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGIVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(22596..24005)
                     /locus_tag="VQ548_001211"
     CDS             complement(22596..24005)
                     /locus_tag="VQ548_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET2654066.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSLCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            24163..24891
                     /locus_tag="VQ548_001212"
     CDS             24163..24891
                     /locus_tag="VQ548_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2654067.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            25351..25545
                     /locus_tag="VQ548_001213"
     CDS             25351..25545
                     /locus_tag="VQ548_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2654068.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSDVTLITGKNGTGKSTLL"
     gene            complement(25911..27221)
                     /locus_tag="VQ548_001214"
     CDS             complement(25911..27221)
                     /locus_tag="VQ548_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HET2654069.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            27458..28330
                     /locus_tag="VQ548_001215"
     CDS             27458..28330
                     /locus_tag="VQ548_001215"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HET2654070.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT         8905 a         5056 c         5921 g         8529 t
ORIGIN      
        1 gtgcattggt tagttgttta ctttcttcat aaattttatt gtatcatatt tttgtttcac
       61 aggaagtcta ataaataaaa attctttaaa attttgttgg gaaaatggga aaagatataa
      121 atggaaactt agtataacac ttggaaaact ctgtaaaaat agtaagtcaa ttcatgtccc
      181 gttttttctc tagggaagtt gggcggctat atttatatga ccatttgtcg taataaacat
      241 ccctaccaag ggtcaataga aataaattca acgaaacttt tgctgtcaga tttagatgcc
      301 caatttgtca tttatactct ttcatatagg actttctata aggatggaaa aaagaaggga
      361 aatttgataa gataggaata tggattttga aaaaattgaa caagcttata cctatttact
      421 agagaatgtc caagtcatcc aaagtgattt ggcgaccaac ttttatgacg ccttggtgga
      481 gcaaaacagc atctatctgg atggtgaaac tgagctaaac caggtcaaag acaacaatca
      541 ggcccttaag cgtttagcac tacgcaaaga agaatggctc aagacctacc agtttctctt
      601 gatgaaggct gggcaaacag aacccttgca ggccaatcac cagtttacac cggatgctat
      661 tgctttgctt ttggtgttta ttgtggaaga gttgtttaaa gaggaggaaa ttactatcct
      721 cgaaatgggt tctgggatgg gaattctagg cgctactttc ttgatctcgc ttgataaaaa
      781 ggtggattac ttgggaatgg aagtggatga tttgctgatt gatctggcag ctagcatggc
      841 agatgtaatt ggtttgcagg ctggctttgt ccaaggagat gccgttcgtc cacaaatgct
      901 caaagaaagc gatgtggtca tcagtgactt gcctgttggc tattatcctg atgatgccgt
      961 tgcgtcgcgc catcaagttg cttctagcca agaacatact tacgcccatc acttgctcat
     1021 ggaacaaggg cttaagtacc tcaagtcaga cggatacgct atttttctag ctccgagtga
     1081 tttgttgacc agtcctcaaa gtgatttgtt aaaagaatgg ctgaaagaag aggcgagtct
     1141 ggttgctatg attagtctgc ctgaaaatct ctttgctaat gctaaacaat ctaagactat
     1201 ttttatccta cagaagaaaa gtgaaatagc agtggagcct tttgtttatc cacttgctag
     1261 cttgcaagat gcaagtgttt taatgaaatt taaagaaaat tttcaaaaat ggactcaagg
     1321 tactgaaata taaaatagat tttgttataa tagttgaaaa cgcttaaaaa ggggtatcat
     1381 gttatgacaa aaacaattgc aatcaatgca ggaagttcaa gtttgaaatg gcaattatac
     1441 ttaatgccag aggaaaaagt gttagccaaa ggtttgattg aacgtatcgg tttgaaagat
     1501 tcaatttcaa ctgtaaaatt tgacggccgt tctgaacaac aaattttgga tatcgaaaat
     1561 catacacaag ctgttaaaat tttattggat gacttgattc gtttcgatat tatcaaggct
     1621 tatgacgaga ttacaggtgt tggccaccgt gttgtagcag gtggagaata tttcaaagaa
     1681 tcaacagttg ttgagggaga tgttttagaa aaagttgaag agttgagttt gttggctcct
     1741 ctacacaacc cggccaatgc agcaggtgtt cgtgctttca aggaattgtt gccagacatt
     1801 accagtgtag ttgtttttga tacttccttc cacacaagta tgccagagaa agcttatcgc
     1861 taccctctac caacaaaata ttacacagaa aacaaggttc gtaaatacgg tgctcatggt
     1921 acaagtcacc agtttgtagc aggagaagct gcaaaactct tgggacgtcc attagaagac
     1981 ttgaagttaa ttacctgtca tattggtaac ggaggctcaa ttacagctgt gaaagccggc
     2041 aaatctgtag acacttctat ggggttcact cctcttggtg gtattatgat gggaacgcgt
     2101 acaggggata ttgatccagc tatcattcct tatttaatgc aatatacaga ggattttaac
     2161 acaccagaag atatcagtcg tgttcttaac cgtgaatcag gtcttttggg agtttctgct
     2221 aattctagcg atatgcgcga tatagaagca gctgtagcag aagggaatca cgaggctagc
     2281 ttggcttatg aaatgtatgt tgaccgtatc caaaaacata tcggtcagta ccttgcagtg
     2341 ctaaatggaa cagatgccat tgttttcaca gcaggtgtcg gtgaaaatgc agagaatttc
     2401 cgtcgtgatg taatctcagg gatttcgtgg tttggttgtg atgttgatga tgaaaagaat
     2461 gtctttggcg ttacaggaga catctcaaca gaggcagcta aaatccgtgt cttggttatt
     2521 ccaacagatg aagaattagt cattgcccgt gacgttgaac gcttgaaaaa ataagtgaaa
     2581 ctaaaaaaat attcaataca aggagttggg aaagttattt ttccagcttc tttttctgat
     2641 gaaattgtcc aaaaccttgc tatgattggc ttttttgaaa aatatggtat aatagtagta
     2701 atttaataga tggagttgag ttttgaagaa aaactttcgt gtaaaaagag agaaagattt
     2761 taaggcgatt ttcaaggagg ggacaagttt tgctaatcgc aaatttgtgg tctaccaatt
     2821 agaaaaccag aaaaaccatt ttcgagtagg tctatcagtt agcaaaaaac tggggaatgc
     2881 cgtcactaga aatcaaatta agcgacggat tcggcatatt atccagaatg caaaagggag
     2941 tctggtagaa gatgtcgact ttgttgtcat tgctcgaaaa ggagtcgaaa ccttgggata
     3001 cgcagagatg gagaaaaatc tactccatgt attaaaatta tcaaagattt accgggaagg
     3061 aaatgggagt gaaaaagaaa ctaaagttga ctagtttgct aggactgtct ctgttaatca
     3121 tgacagcctg tgcgactaat ggggtaacta gcgatattac agccgaatcg gctgattttt
     3181 ggagtaaatt ggtttacttc tttgcgaaaa tcattcgctt tttatcgttt gatattagta
     3241 tcggagtggg gattattctc tttacggtct tgattcgtac agtcctcttg ccagtctttc
     3301 aggtgcaaat ggtggcttct aggaaaatgc aggaagctca gccacgcatt aaggcgcttc
     3361 gagaacaata tccaggtcga gatatggaaa gcagaaccaa actagagcag gaaatgcgta
     3421 aagtatttaa agaaatgggt gtcagacagt cagattctct ttggccgatt ttgattcaga
     3481 tgccggttat tttggccttg ttccaagccc tatcaagagt tgacttttta aagacaggtc
     3541 atttcttatg gattaacctt ggtagtgtgg atacaaccct tgttcttccg attttagcag
     3601 cagtattcac ctttttaagt acttggttgt ccaacaaagc tttgtctgag cgaaatggcg
     3661 ctacgactgc gatgatgtat gggattccag tcttgatttt tatctttgca gtttatgcgc
     3721 caggtggagt cgccctatac tggacagtgt ctaatgctta tcaagtcttg caaacctatt
     3781 tcttgaataa tccattcaag attatcgcag agcgcgaggc cgtagtacag gcacaaaaag
     3841 atttggaaaa tagaaaaaga aaagccaaga aaaaggctca gaaaacgaaa taaataagga
     3901 ggaatctggt aatggtagta tttacaggtt caactgttga agaagcaatc cagaaaggat
     3961 tgaaagaatt agatattcca agaatgaagg ctcatatcaa agtcatttct agggagaaaa
     4021 aaggctttct tggtctattt ggtaaaaaac cagcccaagt ggatattgaa gcgattagtg
     4081 aaacgactgt tgtcaaagca aatcaacagg tagtaaaagg cgttccgaaa aaaatcaatg
     4141 atttgaacga gcctgtgaag acggttagtg aagaaaccgt tgaccttggt catgtggttg
     4201 atgctattaa aaaaatagag gaagaaggtc aaggtatttc tgatgaagtc aaggctgaaa
     4261 tcttaaaaca tgaaagacat gccagcacta tcttagaaga aactggtcac attgagattt
     4321 taaatgaact tcaaatcgag gaagcgatga gggaagaagc aggcgctgat gaccttgaaa
     4381 ctgagcaaga tcaaactgaa aatcaagact tgaaagagat gggcttgaag gtcgagcaaa
     4441 gttatgatat tgcccaggtg gctacggatg tgactgccta tgttcaagcg attgtggatg
     4501 acatggatgt tgaagctaca ctttcaaatg attataaccg tcgtagcatc aatctacaaa
     4561 ttgacaccaa cgaaccaggt cgtattatcg gctaccatgg taaagtcttg aaggccttgc
     4621 aactgttggc tcaaaattat ctttacaacc gctattccaa aaccttctac gttacaatca
     4681 atgtcaatga ttatgtcgaa caccgtgcag aagtcttgca gacctatgcg caaaaattgg
     4741 cgattcgtgt tttagaagaa ggacgtagtc atcaaacaga tccaatgtcg aatagtgaac
     4801 gcaagattat ccaccgtatt atttcacgta tggatggcgt gaccagttac tctgaaggtg
     4861 atgagccaaa tcgctatgtc gttgtagata cagaataagt aaaatcaggg ttgacctgat
     4921 tttttgctag ctagaggagg ttaaactaat gttgaataag ataagagact atttagactt
     4981 tgctggtttg cagtaccgta atcctgataa agcgggagca gagcgagaga agatgctggc
     5041 attccgccac aaaggacaag aggcccgaaa ggcttttaca gaactggcca aagcctttca
     5101 agcaagccat ccaggatggc aactccaaca gactagtcag tggatgaatc aggcccagcg
     5161 tttgagacca catttttggg tttatctaca gagagacgaa caagtgacag aacctatgat
     5221 ggccttacgt ttgtatggga catctactga ctttggaatt tctttggaag tcagtttcat
     5281 cgaacgtaag aaggatgagc aaacactggg caagcaggcc aaagttttag acattccaac
     5341 cgttaaaggg atttattatc taacctactc taatggtcaa agtcaacggt gggaggcgaa
     5401 tgaagaaaag cgtcgtactt tacgcgagaa ggtgagaagt caagaagttc gaaaagtttt
     5461 agtgaaggta gatgttccta tgacagaaaa ttcgtctgaa gaagaaatcg tagaaggctt
     5521 attgaagtct tattctaaaa ttcttcccta ttatctagct acgagaaaat aagataattt
     5581 gtaaaacatc ataaatcata cagtccaaga gtgaacagtc cgctgtgtaa ttcttggtct
     5641 ttttgtttgc gctttcgcat tatataataa acttacaaaa acaattcaaa aggagaacaa
     5701 ttatggaagt cgtttcaagt gttctaaatt ggttttctag caatattttg cagaatcccg
     5761 catttttcgt aggtttattg gtgttgatag gatatgcact tttgaaaaaa cctgcccatg
     5821 acgttttttc agggtttgtt aaagcaacag tagggtatat gttgcttaac gtgggtgctg
     5881 gtggtttggt tacaaccttt cgtccaatct tagcagctct taactacaaa ttccaaattg
     5941 gtgcagcggt tatcgaccct tactttggac ttgctgcagc aaacaacaaa attgcagcag
     6001 agtttccaga ttttgttgga actgcaacta cagctctatt gattggtttt ggaataaata
     6061 tcttgctcgt agctcttcga aagattacga aggtaagaac cctctttatt actggtcaca
     6121 tcatggtaca acaagctgca acagtatctc ttatggttct attcttagta ccacaattgc
     6181 gcaatgctta cggtacagca gcgattggta tcatctgtgg actttactgg gcagttagtt
     6241 caaatatgac tgttgaggca actcaacgct tgactggtgg tggcggattt gcgattggtc
     6301 accaacagca atttgcaatc tggtttgtag ataaagtagc aggacgcttt ggtaagaaag
     6361 aagaaagttt agacaatctt aaattaccta agttcctctc aatcttccac gatacagttg
     6421 ttgcatctgc taccttgatg ctcgtattct tcggagccat tcttttaatc ttgggtccag
     6481 acattatgtc taataaagaa gtcatcactt caggaactct attcaatcct gctaaacaag
     6541 atttctttat gtacattatc caaacagcct ttaccttctc agtttacttg ttcgttttga
     6601 tgcaaggtgt ccgaatgttc gtatctgagt tgacaaacgc cttccaaggt atttcaaaca
     6661 aattgttgcc aggttcattc ccagcggttg acgttgcagc ttcttatgga tttggttctc
     6721 caaatgctgt cttgtcagga tttacctttg gtttgattgg tcaattgatt acaattgttt
     6781 tgctcatcgt ctttaaaaat ccgattctta ttattacagg atttgtacca gtgttctttg
     6841 acaatgcagc cattgcggtc tacgctgata aacgcggcgg atggaaagcg gctgttatcc
     6901 tttcctttat atcaggtgtc cttcaagttg ctctaggagc tctttgtgtg gcccttctcg
     6961 atttggcatc ttatggtggc taccatggaa atatcgactt tgaattccca tggcttggat
     7021 ttggatatat cttcaaatac cttggtattg ttggttatgt acttgtgtgt ctcttcttgc
     7081 ttgttattcc tcaacttcaa tttgccaaag caaaagataa agagaaatat tacaacggtg
     7141 aagttcaaga agaagcttag tatctagaaa aggagaaata aaatggttaa agtattagca
     7201 gcgtgcggaa atggaatggg ttcatcaatg gttatcaaga tgaaggttga aaatgctctc
     7261 cgtaagctta atcaaacaga ttttacagtc aattcatgca gtgtcggtga agctaaaggt
     7321 ttagcagtag gatatgacat tgtaatcgct tctcttcatt tgattcaaga attggaaggg
     7381 cgaactaatg ggaagttaat tgggcttgat aacttgatgg atgataaaga aatcaccgaa
     7441 aaactcagtc aagcactaca gtaaaaggtt ggagggggct ggacagaaac tgagagttat
     7501 cgtttctgtc cagccccctc tttaaataaa ggaggcagat atgaatttaa aacaagcttt
     7561 aattgacaat gactcgatcc gactaggttt agaggctaac aattggaaag aagcagtcaa
     7621 ggtagcagta gatcccttga ttgaaagtgg ggcaattttg ccagagtatt acgatgctat
     7681 cattgaatcg actgaagagt atgggcctta ctatatcttg atgccaggta tggctatgcc
     7741 ccacgctaga cctgaagctg gtgtgcaaag tgatgccttt tcattgatta ccttacaaaa
     7801 tcctgttgta ttttcagatg ggaaagaggt atctgttttg ttggcactag cagcaacaag
     7861 ttcaaaaatt cacacaagtg tagccattcc acaaattatt gccctgtttg aattagaaga
     7921 ttctattgca cgtttacagg cttgccagac taaagaagat gtcttggcta tgattgaaga
     7981 atctaaggat agcccttatc tcgaaggatt ggatttggaa agttagaaag aggaataaag
     8041 aaatgacaaa aagaatacct aatttacaag ttgcattaga ccattcagac ttgcaaggag
     8101 cgattaaagc agctgtttct gttggtcagg aagtagatat tatcgaagct ggaactgttt
     8161 gcttgcttca agttggaagt gaactggctg aagtcttgcg tagccttttc ccagataaga
     8221 ttattgtggc agacacaaaa tgtgctgatg ctggtggaac agttgctaaa aataatgcgg
     8281 ttcgtggagc agactggatg acttgtatct gttgtgcaac catccctact atggaagcag
     8341 ctctaaaggc tatcaagact gaacgaggag aacgaggcga aatccagatc gagctttatg
     8401 gcgattggac ttttgaacaa gctcagcttt ggctagatgc aggtatctca caagctattt
     8461 atcaccaatc tcgtgatgct cttcttgctg gtgaaacttg gggtgaaaaa gaccttaata
     8521 aggttaaaaa actcattgac atgggcttcc gtgtatctgt aacaggtggt ctagatgtag
     8581 atactctcaa actctttgaa ggtgttgatg tctttacctt tatcgcaggt cgtggaatta
     8641 cagaggctgc ggatccagca ggagcagcgc gtgccttcaa ggatgaaatc aaacgaattt
     8701 gggggtaaat catggtacgt ccaattggaa tttatgaaaa ggcaacccca acacacttta
     8761 cttggctaga acgtttaaat tttgccaagg agttaggctt tgattttgtc gagatgtcta
     8821 ttgacgaacg tgacgagcgt ttagcaagac ttgactggag taaggaagaa cgcttggaag
     8881 ttgtcaaaga aatctatgaa actggtgttc gtattccttc tatctgtttt tcaggccatc
     8941 gtcgctaccc attgggttca aaagatccag ttctagagga aaaatctcta gaactcatga
     9001 aaaaatgtat cgaattagct caagacttgg gagttcgtac gattcaatta gctggttacg
     9061 atgtttacta tgaggaaaag tcaccccaga cacgccaacg ttttatcaaa aatttgagaa
     9121 aagcctgtga ctgggctgaa gaagctcagg tggtacttgc tattgaaatt atggatgatc
     9181 ctttcatcaa tagcatcgaa aaatatttgg ctatagaaaa agagattgac tctcccttcc
     9241 tctttgtata tccagatatt ggtaatgtgt ctgcatggca taatgatatc tatagtgagt
     9301 tttatcttgg tcatcatgcc atcgcagctc tccatctcaa ggatacttat gcagtgacag
     9361 aaagttcaag gggccagttc cgagatgtac cttttgggca aggttgtgtc aaatgggaag
     9421 aagctttcga tattttaaag gaaaccaatt ataatggacc tttcctaatc gaaatgtggt
     9481 ctgaaaattg tgaaacagta gaagaaacac gcgcagccat tcaagaggcg caagcttttc
     9541 tctatccact cattaagaaa gcaggtttga tgtaagatga atcaagtaat caatgctatg
     9601 cgtaaacgag tctgtgatgc caatcaatca ttgccaaaac atggacttgt caaatttacc
     9661 tgggggaatg tatctgaagt caatcgcgaa ctcggtgtca ttgttatcaa accatcaggc
     9721 gtggattatg acgaattgac acctgaaaac atggtagtga ctgatctaga tggtaagatc
     9781 ctagaagggg atttaagacc atcttccgac ctcccaactc atgtgcaatt atataaggct
     9841 tggtcagaaa ttggtagtgt ggttcacacc cattcgacag aagctgttgc ttgggctcag
     9901 gcaggtcgtg atattccttt ctacggaaca acccatgcag attatttcta cggttcaatc
     9961 ccttgcgccc gtagtttgac caaggacgaa gtagaagtgg cctatgaaaa agatactggc
    10021 ctggttatcg tagaagagtt tgaacatcgc ggacttaacc cggttgaagt accaggaatt
    10081 gttgtacgca atcacggtcc attcacctgg ggcaaaaatc cagagaatgc tgtttatcac
    10141 tctgtcgtac tagaggaagt atcaaagatg aatcgcttta cagaacaaat caatccaaga
    10201 gttggacctg ctccccagta catactagaa aaacactacc aacgtaaaca tggaccaaat
    10261 gcttattatg gtcaaaagta agaacgatga aggaggagaa aaagataaat ttagctcctc
    10321 tttttacatt tgatttttat tgagagtaaa gttggagttg aagtaatttt aaaagatttt
    10381 ttagaaatag cgcttgatat atatatggta aaataaaaag aattgctgtg atatcaatag
    10441 atttggggga ttttttaata tggtactgga taaggcaagt tgtgatttgc ttcaatattt
    10501 gatggatcaa gaaacgtcca aaacgattat ggcgatttcg aaagatttga aagagtcaag
    10561 aaggaaaatt tattatcaca ttgacaaaat caatgctgct ctgggtgacg aggcgcttca
    10621 catcattagt attccacgaa ttggtattca cttaacggaa gagcagagag atgcttgttg
    10681 taaactatta tcggaagtag attcgtacga ttatatcatg agtgcgcatg aacgtatgat
    10741 gataatgtta ctatggatag gtatttctaa agaacgtatt acgattgaaa aattgataga
    10801 gttaacagag gtatctagga atactgttct caatgatttg aatagtattc gttatcaact
    10861 aactttggaa caatatcagg tgatcttgca agtgagcaag tcacagggat accaccttca
    10921 tgcccaccct cttaataaaa ttcagtatct tcaatcgctt ctatatcata tttttatgga
    10981 agaaaatgcc acttttgtat ctattttaga agataagatg aaagagaggt tagatgatga
    11041 gtgtttgctt tctgttgaaa tgaaccaatt ttttaaggaa caggttcctt tagttgaaca
    11101 agatttaggg aagaaaataa accatcatga aataactttt atgttgcagg ttctacctta
    11161 tttgctgtta agctgtcata atgttgaaca gtatcaagaa agacatcagg atatagagaa
    11221 agaattttct ttgataagaa aaagaataga gtatcaggtg tctaagaaat taggagaacg
    11281 gttgtttcaa aagtttgaaa tttctttgtc aggacttgaa gtttctcttg tagctgttct
    11341 cctcctctcc tatcgtaaag atttggatat tcatgcagaa agtgatgatt ttcggcaatt
    11401 aaaacttgct ttagaagaat ttatctggta ttttgaatca caaatccgaa tggagattga
    11461 gaacaaggat gatttgttac gaaatttgat gatccactgt aaagccttgt tatttagaaa
    11521 gacttacggt attttttcta aaaatcctct aacaaaacaa attcgatcca agtatggaga
    11581 attattttta gtcactagaa aatctgcgga aattttagaa ggagcatggt ttattcggct
    11641 aacagacgat gatattgcct atttgacgat tcatattgga ggatttttaa aatatacacc
    11701 atcatctcaa aaaaatatga aaaaagttta tctcgtttgt gatgaaggtg ttgcggtttc
    11761 gagacttttg ctgaaacaat gcaaacttta ttttccaaat gagcaaattg acactgtatt
    11821 tacaacagaa caatttaaga gtgtggaaga tattgcacaa gttgatgtag tgattactac
    11881 taatgatgat ttggatagca gatttccgat tttaagggtt aatcctatcc ttgaagcaga
    11941 agatattttg aaaatgctag actatcttaa acacaatata tttcgtaata agagcaaaag
    12001 tttcagtgaa aatctttcta gtcttatttc gtcttatatt gtagacagca agttggctag
    12061 taagttccaa gaagaggttc aaacacttat aaatcaagaa atagtagttc aagctttttt
    12121 ggaagatatt tgaaggacag tccaatgatg aacacaaacc tgtgtttttc ttggtctttt
    12181 ttagtgtttt gaagggtggt atactaatct caaagataac aattatatcc aaaggaggca
    12241 acatatgcca aacgtcaaag aaattacaag agagtcatgg attttagcca ctttcccaga
    12301 gtggggaaca tggttgaacg aagaaatcga agaagaagtc gtacctgaag gcaactttgc
    12361 catgtggtgg ctaggcaact gtggtacttg gattaagaca ccagctggtg ctaacgttgt
    12421 catggacctt tggtcaaacc gtggaaaatc aaccaaaaaa gtgaaagata tggttcgtgg
    12481 gcaccaaatg gcaaatatgg caggtgttcg taagctgcaa ccaaacttgc gtgttcagcc
    12541 aatggttatc gatccatttg ctatcaacga actagactat tacttagttt cacacttcca
    12601 cagtgatcat atcgacccat acacagctgc agcaattctc aataatccta agttagagca
    12661 tgttaagttt atcggtcctt accactgtgg acgaatctgg gaaggatggg gtgttccaaa
    12721 agaacgtatc atcgttgtta aaccaggtga cactatcgaa ttaaaagata tgaagattca
    12781 tgcagtagaa tcatttgacc gtacttgctt ggtaactctc ccagtgaacg gtgctgatga
    12841 gacaggcggt gaacttgctg gcttggctgt tacagatgaa gaaatggctc aaaaggctgt
    12901 taactatatc tttgaaacac caggtggaac catctatcat ggtgcagatt ctcacttctc
    12961 aaactatttt gcaaaacatg gtaaagactt taaaattgat gttgctttga ataactatgg
    13021 tgaaaatccg gtaggtatcc aagacaaaat gacatctatc gaccttcttc gtatggcaga
    13081 aaatctgcgt accaaagtca ttatcccagt tcactatgat atctggtcta acttcatggc
    13141 ttctactaat gagattctag aactttggaa aatgcgaaaa gatcgcttgc aatacgattt
    13201 ccatccattt atctgggaag ttggcggtaa gtacacttat cctcaagatc aacacttagt
    13261 agaataccat catccacgtg gttttgatga ttgttttgaa caagactcta acattcaatt
    13321 taaagctttg ctataatata aaaatattct ttggaggtta tccgtatgtt gcatgatacg
    13381 gataattttc atataatagt aaaatagaat gtgtgattca ataatcacct caaatagaaa
    13441 ggaaattcta tgtcaaatct atctgttaat gcaattcgtt ttctaggtat tgacgccatt
    13501 aataaagcca actcaggtca tccaggtgtg gttatgggag cggctccgat ggcttacagc
    13561 ctctttacaa aacaacttca tatcaatcca gctcaaccaa actggattaa ccgcgaccgc
    13621 tttattcttt cagcaggtca tggttcaatg ctcctttatg ctcttcttca cctttctggt
    13681 tttgaagatg tcagcatgga tgagattaag agtttccgtc aatggggttc aaaaacacca
    13741 ggtcacccag aatttggtca tacggcaggg attgatgcta cgacaggtcc tctagggcaa
    13801 gggatttcaa ctgctactgg ttttgcccaa gcagaacgtt tcttggcagc caaatataac
    13861 cgtgaaggtt acaatatctt tgaccactat acttacgtta tctgtggaga cggagacttg
    13921 atggaaggtg tctcaagcga ggcagcttca tacgcaggct tgcaaaaact tgataagttg
    13981 gttgttcttt atgattcaaa tgatatcaac ttggatggtg agacaaagga ttcctttaca
    14041 gaaagtgttc gtgaccgtta caatgcctac ggttggcata ctgccttggt tgaaaatgga
    14101 acagacttgg aagccatcca tgctgctatc gaaacagcaa aagcttcagg caagccatct
    14161 ttgattgaag tgaagacggt tattggatac ggttctccaa acaaacaagg aactaatgct
    14221 gtacacggcg cccctcttgg agcagatgaa actgcatcaa ctcgtcaagc cctcggttgg
    14281 gactacgaac catttgaaat tccagaacaa gtatatgctg atttcaaaga acatgttgca
    14341 gaccgtggcg catcagctta tcaagcttgg actaaattag ttacagatta taaagaagct
    14401 catccagaac tggctgcaga agtagaagcc atcatcgacg gacgtgatcc agtcgaagtg
    14461 actccagcag acttcccagc tttagaaaat ggtttttctc aagcaactcg taattcaagt
    14521 caagatgcct tgaatgttgt ggcagctaaa ttaccaacct ttctaggtgg atcagctgac
    14581 cttgctcact caaacatgac ttatatcaag acggatggac ttcaagacga tgccaatcgc
    14641 ttgaatcgta acattcagtt tggtgttcgt gaatttgcaa tgggaacaat cttgaacggg
    14701 atggcccttc atggtggact tcgtgtatac ggtggaactt tcttcgtctt ctctgactat
    14761 gtgaaggcag ctgtccgctt gtcagcctta caaggacttc ctgtgactta tgtctttacc
    14821 catgattcaa tcgcagttgg ggaagatggt ccgactcatg aaccagttga gcatttagca
    14881 ggtcttcgtg ctatgccaaa tctaaatgtt ttccgtccag cagatgcgcg tgaaacgcaa
    14941 gcagcttggt accttgcagt gacaagtgag aaaacaccaa ctgcccttgt cttgacacgt
    15001 caaaatttga ctgttgaaga tggaacagac ttcgacaagg ttgctaaagg tgcttatgtt
    15061 gtatatgaaa atgcagccga ctttgatacc atcttgattg cgacaggttc agaggttaat
    15121 cttgctgtct cagctgctaa agaattggct agtcaaggcg aaaaaatccg cgtagtcagc
    15181 atgccatcta cagatgtctt tgataaacaa gatgcagctt acaaggaaga aattcttcca
    15241 aatgcagtcc gccgtcgtgt tgcagtcgaa atgggtgcaa gtcaaaactg gtacaaatat
    15301 gttggtctcg atggtgccgt tctaggtatt gataccttcg gagcctctgc cccagcacca
    15361 aaagtattgg cagaatatgg ctttactgta gaaaatcttg taaaagttgt tcgaaacttg
    15421 aaataatcct aaaaatcagg gcgtaagctc tggtttttct taccagaaaa gtaaggtaca
    15481 atcttgtaaa agtagctgaa atttgatata gtagtcctat gtaaaagaca aaggagaaaa
    15541 caatgaatcc aaatattact tttttaatca tgcttgtagg tatgatggcc ttgatgttct
    15601 ttatgcaacg ttctcaaaag aaacaagctc aaaagcgtat ggaaagctta aataaactac
    15661 aaaaaggcta tgaagtgatt acaatcggtg gactttatgg aacagtcgat gaagtagata
    15721 cggagaaggg aacaatagtt cttgacgtag agggagttta cttgactttt gaactagctg
    15781 ctatcaagac agtattaccg ctgaaagaaa cagcttcact agaaggcgca attgaaaaat
    15841 aagacgggat cacgaactcc cgtttttcta taaaagaaag gaaatgggat gaaaaaatta
    15901 gtctttgtct gtctgggaaa tatttgccgt agccctatgg ccgagtttgt tatgaaatca
    15961 atgacagata actacgaaat ccaaagtcga gcaacttcct cttgggaaca tggcaatccg
    16021 attcataagg ggactcaggg aatttttcaa gagtatgaga ttccttatga caagaacaag
    16081 acatcgcttc agattagtaa ggaagatttt gaagcctttg attatattat cggaatggac
    16141 gcttcaaata tttctgactt acgtcagatg tgtccagtag actgtcaaga taagatttac
    16201 tcattttcat ctgaaagtgt tccagaccct tggtatacag gagattttga agaaacctat
    16261 cgacgtgttc aagagggctg tcaagcttgg ttagaacgtt tagaaaagga gagttaaggt
    16321 ggaaaatctt acgaattttt acgaaaagta tcgtgtctat ctgactcgtc cacgtttaga
    16381 gcttttggca gtagttacca ttgttttctg tgctgtactc gtcttttttc taaatattcc
    16441 aggaaaaggt gtcttaaaac tcgataatgg aacgattgtt tatgatggca gtcttgtccg
    16501 cggtaaaatg aatggccaag gtaccattac cttccaaaat ggagaccaat atacaggtgg
    16561 cttcaacaat ggagccttca acggaaaagg tacctttcaa tctaaagaag gctggaccta
    16621 cgaaggtgat tttgtaaatg gtcaggctga aggaaaaggg aaactaacaa cagaacaaga
    16681 agtcgtttat gaaggaactt ttaaacaagg cgtttttcaa caaaaataaa gcctccttat
    16741 caaaggaggt attattagaa tcgcaaggta agcgcttacc tgcaaatccc tttctttcca
    16801 aatccctctt ccaagcaagt ttgtgaaata aaaaatattt gaaataaatt tcacaaactt
    16861 caaagataaa acctgataag aaaagaaaat gagaaaagtt tcacaagagt ttaaaaattc
    16921 tttgtgaaat gtttatgaaa ctgtttacaa agttgaaata atgcgttata ataaacttgt
    16981 gaaaaaatta acaaaggata tcgttccttg aaagctatgg aggaaaatat ggctgataaa
    17041 aaaactgtga caccagagga aaagaaactc gttgctgaaa aacacgtaga tgagttggtt
    17101 caaaaagctc tagttgccct tgaagaaatg cgtaaattgg atcaagaaca agttgactac
    17161 atcgttgcca aagcatcagt agcagctttg gatgcccacg gagaattggc tttacatgcc
    17221 tttgaagaaa caggacgtgg tgtatttgaa gataaagcaa ctaagaactt gtttgcttgt
    17281 gaacacgtgg taaacaacat gcgtcacact aaaacagttg gcgttatcga agaagatgat
    17341 gtaacaggat tgaccctgat tgctgaacca gttggtgttg tttgtggtat cactccaaca
    17401 acaaacccaa catcaacagc gatcttcaaa tcattgattt cattgaagac acgtaatcca
    17461 atcgtctttg ccttccatcc atcagctcaa gaatcatcag ctcatgcagc tcgtatcgtc
    17521 cgcgatgcag ctatcgcagc tggtgctcct gaaaactgtg tacagtggat cactgaacca
    17581 tctatggaag caactagtgc ccttatgaac cacgaaggta ttgcaacaat ccttgcaaca
    17641 ggtggtaatg ccatggttaa agccgcatac tcatgtggta aaccagctct tggggtaggt
    17701 gccggaaacg ttccagctta tgttgaaaaa tcagcaaaca ttcgtcaagc agcacacgat
    17761 atcgtcatgt ctaaatcatt tgataacggt atggtctgtg catctgaaca agcagttatc
    17821 attgataaag aaatttacga tgaatttgta gcagagttca aatcttacca cacttacttt
    17881 gtaaacaaaa aagaaaaagc tcttcttgaa gagttctgct tcggcgtcaa agcaaacagc
    17941 aaaaactgtg ctggtgcaaa attgaacgct gacatcgttg gtaaaccagc aacttggatt
    18001 gcagaacaag caggatttac agttccagaa ggaacaaaca ttcttgctgc agaatgtaaa
    18061 gaagttggcg aaaatgagcc attgactcgt gaaaaattgt caccagttat tgcagttttg
    18121 aaatctgaaa gccgtgaaga tggtattact aaggctcgtc aaatggttga atttaacggt
    18181 cttggacact cagcagctat ccacacagct gacgaagaat tgactaaaga atttggtaaa
    18241 gctgttaaag ctattcgtgt tatctgtaac tcaccttcta cttttggtgg tatcggggac
    18301 gtttacaatg ccttcttgcc atcattgaca cttggatgtg gttcttacgg acgcaactca
    18361 gttggggata acgttagtgc cattaacctc ttgaatatca aaaaagtcgg aagacggaga
    18421 aataacatgc aatggatgaa acttccttca aaaacatact ttgaacgtga ttcaattcaa
    18481 taccttcaaa aatgtcgtga cgttgaacgt gtcatgatcg ttactgacca tgccatggta
    18541 gagcttggtt tccttgatcg tatcatcgaa caactggacc ttcgtcgcaa taaggttgtt
    18601 taccaaatct ttgcggatgt agaaccggat ccagatatca caactgtaaa ccgtggtact
    18661 gagattatgc gtgccttcaa accagatacc atcatcgcac tcggtggtgg gtctccaatg
    18721 gatgctgcca aagtaatgtg gctcttctac gagcaaccag aagtggactt ccgtgacctt
    18781 gtccaaaaat tcatggatat ccgtaaacgt gccttcaagt tcccattgct tggtaagaag
    18841 actaaattca tcgcgattcc aactacatct ggtacaggat ctgaagtaac accatttgcc
    18901 gttatctctg ataaagcaaa caaccgtaaa tacccaatcg ctgactactc attgacacca
    18961 actgtggcaa tcgtagatcc tgctttggta ttgacagttc caggatttgt tgctgctgat
    19021 actggtatgg acgtattgac tcacgcgaca gaagcatacg tatcacaaat ggctagtgac
    19081 tacactgatg gtttagcact tcaagccatt aaattggtct ttgaaaatct cgaaagctca
    19141 gttaagaatg cagacttcca ctcacgtgag aaaatgcata acgcttcaac aatcgctggt
    19201 atggcctttg ccaatgcctt cctaggtatt tctcactcaa tggcccataa gattggtgcg
    19261 caattccaca caatccacgg tcgtacaaat gctatcttgc ttccatacgt tatccgttac
    19321 aacggtacac gtccagctaa gacagcaaca tggcctaagt acaactacta ccgtgcagat
    19381 gaaaaatacc aagatatcgc acgcatgctt ggacttccag cttctactcc agaagaaggg
    19441 gttgaatctt acgcaaaagc tgtctacgaa ctcggtgaac gtattgggat ccaaatgaat
    19501 tttagagacc aaggaattga cgaaaaagaa tggaaagaac attctcgtga attagccttc
    19561 ctggcttatg aagaccaatg ttcaccagct aacccacgtc ttccaatggt agaccatatg
    19621 caagaaatca tcgaagatgc atactatggc tacaaagaaa gaccaggacg ccgtaaataa
    19681 ttgtttatca gtctagaagc aagacaaaaa ctcaatttga gggaaagatc cagtaatttt
    19741 tctatgataa aaggcatcct atcaaggttt ttgaacacct gataggatgc ctttttatga
    19801 tattgaggcc tttttgccct ttttgaaaaa ctagaataga aacaaaatat ataatagatt
    19861 gaaactggaa tagtacactt ctgcttctaa aacattgtta gaattcgatt tgactgtcct
    19921 gatcgatttg tcctattcct atttcatttt actatataaa aaatatagta tagtagactg
    19981 aatctaaaat agtacgaaac aattgctaaa acatttatag aaattaattt tactttcctg
    20041 atagagttgt tcacatctta tttcaattca ctatagttta atttaagagt agtatttact
    20101 aaggcccaat taaaatcaaa gagcaaacta gaaaacgagt gccattcagc tcaaaacact
    20161 gatttgagat tgcagataag actagcccct cattaacagg tttacgataa aacgatgaca
    20221 aggtgtgttg ctttttgatt tctaaagagt ataatgatag atctctataa aataagtgcg
    20281 aaggaaatga gcttttatag tcctttcgtt ttaaaatact atctcagatg ttcttatatc
    20341 gacaagaagt ttttgagtca ttccctcatc atacatatta aataaatagt ggctcattca
    20401 attttttact agaataataa gctagtatag taaactgaaa taagatataa acaaataaat
    20461 tggagcttaa catctatttc cagcaatttt ttagaaactg cagtggacta ttctaaattc
    20521 aacacattat aaaaactaga gtaaaagaaa aggattggat cttgtgtaat gcaggatcta
    20581 atcctttcaa tcattttgtc caacttttgg aggttcctac aatgtagccg tcattaataa
    20641 agacagatgg gaacgacagt gttcctattt attttgatag agatcgatga attctttaga
    20701 tagcaactga ataatctctg ttgaagccat ttggtcttct gcatgcataa atagcaagga
    20761 gaatcctatt ttttctccag tagcttcttt ttgtatgaga ttagagtgaa tcttgtgcgc
    20821 ttctactaag gagtcttccg cttcttcaac tttaattttc gcttctttta aatttcctgc
    20881 cttagctagt tggatggctt caataaagga tgatttggct gctccactat tggcaatgag
    20941 ctgaaaacag atatattcca tttcttctgt catcttattt ctcctatcca tgcaagtgct
    21001 tgttccagaa cttttgctcc attcatcatt ccgtaatccc gcatatcaat ggtatctaca
    21061 gggatatttc ctgcaatttc tttcacagca agtaactcat aacgaatttg tggcccaatt
    21121 agaatgacat ctgcttcatg gatattcttt ttcgcttctg tcattgattt tgcttggata
    21181 gaaatttcaa tcccacgttc agtcgcactt tgttgcattt ttttaacaag catacttgtc
    21241 gacattcccg cattacatac taataaaatt tgtttcataa tcttaacctt ccatttcttg
    21301 ctcaacaact ttgtcattaa ctttgataaa tggaatgtat agaagaactc caagtgcaaa
    21361 gatgatgaat tgaactagaa ctgctctcac gtcccctgct gttgctaacc atgcatttaa
    21421 gaatactggt gtagtccaag gaacttgtat aaatgcagga ctcatgaatc ctgtaactgt
    21481 tgctaagtag ctgattaaaa taccaaggac tggaactgtg ataaatggaa tagctaatga
    21541 aatgttataa acgattgggt aaccgaataa tactggttca ttgatattga agataccagg
    21601 tccaaaagat aatttagcca cgtttttaga aacagcattg cgactcacta agaatgttgc
    21661 tattaataaa cataatgtag atccactacc acccattaaa gcgaatgttt gtatttgtga
    21721 taagttgatg atgtgtggaa tggcttgtcc attatttgct gcagtgatgt tttcagtaat
    21781 gttaattaat agtaatggtt ctaggatggc actgtaaata actgcttggt gaataccaaa
    21841 tagccataac atatttccta aagagtaaat aataatgacc ccgattaagc ttgtaccaat
    21901 atgacgaatt ggttcttgaa taaagattgt aatgattgag attaagttca ttccagttat
    21961 attgaataat aatgctgaaa caatcccaaa taaggagatg acagtcatga ctggaagtaa
    22021 tacgctaaat gatctactaa cagctggtgg aatattttca ccaaggttca tttgtaaagc
    22081 tttaacgttt gataattcaa tgaataattc tgttgcaata atcgctacga taaccccggc
    22141 gaacattgcg cctgtacctg tgttgttgaa tgaaagaaca cctgaaatgt ttacagcatc
    22201 ttttgctccg tcaggaacta cagaaactgt atttggcatc atcacaatta aagaaactaa
    22261 tgatagcatt gatgctgctg acgggttttc gaaatctctg tttttagcta agaaataacc
    22321 aaccattaca gcaataatca tacctgaaat acttaaagta ccgtttgcaa ttgttattcc
    22381 ccaatattgg aattttgtta atgtatcccc ttggaaaatc cacttaaata ccgtgttgtt
    22441 caaaagaacg attaaacctg ccaaaatata taatggcatt actgttacga atgcatctct
    22501 tagggttttt aaatgaattt ggttccctag tttaccagca aaggtggcaa attgatctat
    22561 aaattttgag tttttcatct gaatatctcc tctctttact cctcaatttc tacttcaaaa
    22621 ccgttattgt cacttacttt gcgataccat cttcctgagc tcttgatggt tctcttttgc
    22681 gtttctaaat caacggagat aaatccgtaa cgattcttat atgcattatt ccaagaccag
    22741 caatcaaatg cggtccaagc gtggtatcca aaacagagac ttccctcttc aatggcttta
    22801 tgtagccatc ttaaatgttc ttcataaaat tcaatacgat acacgtcatc gataactcca
    22861 ttttcatcga taaaccgtgc ttcgttttca acacccattc cgttctcact gataaaccat
    22921 gggatattac catattcttc cttcacaatc atagcaatat cataaatggc tttcggaaaa
    22981 atttcccaac cacgatatgg attcatgcga cgctccggcc attcatactc tttgaagtat
    23041 tggtctggca tccagggcgt ctgatattcc tcaggatttg cttgtgcttg aacacgtttt
    23101 ggatggtagt agtttactcc aagaaaatca accgtatttg atttcatcag ttgaagctct
    23161 ttttcggtat gactccataa cacgccatct ctctctagct gttttaccaa tctttctggg
    23221 aaagttcctt taacagctgg attcaagaag actttgttaa agaagtcttc tgtaaatcga
    23281 cttgcttcta agtcttctgg agaattactt cttggataag caggtgtcaa gtttaaaata
    23341 atcccaatct ttccatcaag tcctaatgag cgatatagtt gaatcacttt tgcactagca
    23401 aggtttagat tatagatgac ttgtacggcc tcttttccct ttccttttag atttggataa
    23461 tggaaagcat ataagtatcc tgcttctgga atgaccattg gctcattgaa agttgtccag
    23521 taatgaacct tatctccaaa gcatgtgaaa gcagtcttgg caaacttcac gaataactcc
    23581 actacatgtt tgctttccca accaccgtat ttttgaagaa gttccactgg taaatcaaaa
    23641 tgatgtaaat tcatcacaag atccatctgg ttctttttag cttcttcaat gatggcattg
    23701 tagaaagcaa taccttttgg atcaggctca cctgtctcta aattcttgat gagtcgactc
    23761 cattggatgg aagtgcggaa agaattaact ccaatttcct tcatcaagtg gaaatcttcg
    23821 gtgtaagtat gaaaaaagtt actggctaca agaggtccga cattatcgaa aaaatcttct
    23881 ggatgcgttt tgaaccagta gtccatcaca ttttcatgta cttttccata ttgaccttct
    23941 gtctgaggtc cgctagaagc agctccccac caaaacagat taggaaatac taactttttt
    24001 ttcatgctca acctcctttc tattatgcta tacataaagt atagcataat tttaaaattt
    24061 gtctagacat ttttaaaaat tgttgataca tatattgtgt ttgcctcatt tcttgaactt
    24121 tgttatacta ctattagaat attatagaga gaaccagatt aaatgagtac aaaatattta
    24181 tttatttaca atgagattcg tgaaaagatt ctctgtaata aatataccat gaacgaacaa
    24241 ttgcctgatg aaatgacatt agctaaacag tttgcctgta gtcgaatgac gatcaaaaaa
    24301 gctttagact tgttagtttc tgagggctta atttttagaa aacgtgggca gggaaccttt
    24361 gttctctctc gtggcagctc aaaaagaaaa ttaatcgttc cagaaagaga tatccgggga
    24421 ctgacaaaaa tatctgaaga tgctcattct acaattgact cgaggattat tcacttcaaa
    24481 ttagaatttg caaatgaatt tttagcagaa aaactacagg tcgctttgca gagtccagtt
    24541 tataatattt accgcctgcg tattattgac ggtaaacctt atgttctgga acaaacttat
    24601 atgagtaccg atgttattcc aggtattact gaagatattt tacaaaaatc gatttacaat
    24661 tacattgaag gaaagttagg attgcatatt gccagtgcta caaaaatctt gcgagcttct
    24721 tctagttcag aaaatgagca acattacttg cagctccttc caacagaacc ggtatttgaa
    24781 gtagaacaag tggcttattt ggataacgga actccgtttg agtactcgat tagtcgtcat
    24841 cgctatgatt tatttgaatt taattctttt gcattacgac attcctccta ggagaaaatg
    24901 tgaaaatgaa gccaatcttt tacaggctct agtttaagaa aaatttaaaa cagggcaaga
    24961 aggtcccatc tatgcttaaa tggtttctct tttctaaata agatggcttt aaaagagtga
    25021 tcgttttatc catcatgttg aaaaatatct tcgtatagct tatagagtag gtactgaaat
    25081 tgttcacctg atctacttct tatagttatt tagttttaaa tagtgtttca aacattctta
    25141 cactgacgag aagtttttga gtcttttctt gtaacacata tagtatactg aggttagaat
    25201 agtagactgt gacttctaac aaattgctag aaatgaattt caatctccca atttatttgc
    25261 ttatatatta ttttaatata ttaaataaat tctggatcat aatcatttaa aaaaatttta
    25321 tttttttatt tttcattacg aataatatag atgaagggga aagagtatga aaacagaact
    25381 gtttcttttg ctattagttc aaaaggagaa aaaatgaaag tagaaaatat ttcgtatagg
    25441 gtggatcatc gtatattgtt tgataatatt tcttttgata cttcgagttc agacgtgaca
    25501 ttaattactg gtaaaaatgg tacaggaaag tcaactttac tatagtggat tgaaactaga
    25561 atagtacaca tctacttcta aaatattgtt agaaatcgat ttgactatcc tgatctattt
    25621 gtcctgttct tatttcattt cactatatct caaattgagt atgacgaagt gcgctcccat
    25681 gtcctgggaa cgcactttct tcatattttt catattcttg aatccatcga taaagactat
    25741 tgggatgaat ttttaaagtt gaactaatca tttttacagg atgaggttta cagcagagag
    25801 tttgaaggct ttatcaaagg tttttcttgg cataatgact tttcctcgtt tccacttaat
    25861 tttgtgtcta ctttattata ccaagtccac ccttaagtta gataataaat ctaacttaag
    25921 gaagctagaa ggatgagaat ccaggtggtc aagagtccca aacttaagct gattgggaca
    25981 cccagaataa tttgcttttt gaaggcaagg ccacgttcct ctatattggg aagtgagagt
    26041 tgaatgagag aaccagctga tgaaaagggt gagatattag tagatagagc gccaataacg
    26101 gtggctgttg tgagtaagtg aatatcaatc tggggatttt gagcactgat gatagcaatg
    26161 atgggaaaga gggctggagc tacaacggat agggtggaac taaagagtga catcaccccg
    26221 gctatcacac aaaagaacag aggtaaccag aaatgaggaa tggatgttgt catgaggtgc
    26281 cctatcagtg tgactaaacc tgacttgacc gctagagaca ttagtaagct catgccgcag
    26341 agcatgataa ttgtagccca gggaacttta gccaaaatgg cttcttgctt ccctaatttg
    26401 agccttaagg cgaggcagac catgagtatt gagacaaagc caatatcaaa tgtttttcga
    26461 taagtagcta tccaggcgat gtttgggaaa atgagatgca acaagggaaa aagccaaacc
    26521 aaaaccatgc tgctgatcat gagcaaggtg gtttgtcttt gaaccttgct gaggagtggt
    26581 ggttggtcaa tagtcaagga tgagtttgtt cttcccttac tatagtgact gtaacaggat
    26641 aataaaagca agacaatgag tgggtagata atgctgacga taaagatatg attgccaagt
    26701 gaaaaagctt gctcttccca tcccatttgc ttaaacaggc cttgaaagac aatgcctgag
    26761 ctactggtta tcaaattagc ccctcctgaa gctccccaat tgacggcttg agctccaatc
    26821 aaagggtgtt tgtccgcttt ttgacagaga gtaatcgcta gaggacagca aacggccata
    26881 gtagtgaaaa atccagcacc taaagcagac aaaagggttg ccatcaggta taaaatcatg
    26941 tagagggcgt tagggtaggt gcgtgtgcgg tagagaatgt gttgagccaa aacatcaaga
    27001 gtaccgttag ttattgcaaa gttataaaag agagagacgc taaaaatggt aaaaaagagt
    27061 gaggttggcc aaaaatgaag aagttctttg gggcttaatc ccatgagagt ggttgcgatg
    27121 aggtaagaaa aagcaatagc cagcaggcca atattgattt tggtgcggta accaattcca
    27181 atggctagag caatggcgct aatcattatt aaatgaatca ttgaattgtc ctttcagtta
    27241 gaatatggaa ataggttggc aattttggcg ctcaaaagac cacctgtttc ctattggtac
    27301 ttgactatta tacacaaaaa aaatacaatt gtcttgacaa ttgtattgac acttgttaga
    27361 attaaaaatg aggtattcag gcttgtgatt tcctatggaa gttaatagtg attgcctcta
    27421 atgcttacaa gtgatattaa aaatagagga cctagtgatg tcaatcattt caactgattt
    27481 aacccctttt caaatagatg atacattgaa agcagccttg cgagaagatg ttcattccga
    27541 agattacagt accaatgcca tttttgatca tcatggccaa gccaaggtgt cgctttttgc
    27601 caaggaagct ggtgttttag cggggctaac cgtttttcaa agggttttta ccctatttga
    27661 tgccgaggtg accttccaga atcctcatca atttaaggat ggggatcgtt tgactagtgg
    27721 cgatttggtt ttagaaatca taggctcggt gagaagtctc ttaacatgtg aacgcgttgc
    27781 cttgaatttt ttacaacatt tatcagggat tgcttcgatg acagctgctt atgtagaagc
    27841 cttaggcgat gattgcatta aggtatttga tactcgaaaa actactccta atttacgtct
    27901 ttttgagaaa tatgcagtga gagttggcgg tggctataat catcgcttta atttatcaga
    27961 tgctatcctg ctaaaagaca atcacattgc ggcagtaggt agtgttcaaa aggcaattgc
    28021 tcaagcgcgt gcctatgccc cttttgtgaa aatggtcgag gtggaagtgg aaagccttgc
    28081 tgctgccgaa gaagctgcgg cggcgggtgc tgatattatc atgttggata atatgtcatt
    28141 ggaacagatt gaacaggcca ttaccctaat tgcaggacgt tctcggattg aatgttctgg
    28201 aaatattgat atgaccacta ttagccgttt tcgtggttta gcgattgatt acgtctccag
    28261 tggtagttta acccatagtg ctaagagtct tgatttttcc atgaaggggt taacctacct
    28321 tgatgtctaa gttgtaaaat aaactaactt tttaaaggat gtctttcctc tagaacgagt
    28381 tttatgtcag atagtttaaa cgcctcttca a
//
LOCUS       DAVBEM010000028        27491 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVBEM010000028 DAVBEM010000000
VERSION     DAVBEM010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27491
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.028"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            98..1357
                     /locus_tag="VQ548_001216"
     CDS             98..1357
                     /locus_tag="VQ548_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HET2654071.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQIQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    1433..1568
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            1607..2107
                     /locus_tag="VQ548_001217"
     CDS             1607..2107
                     /locus_tag="VQ548_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HET2654072.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            2183..2551
                     /gene="rplL"
                     /locus_tag="VQ548_001218"
     CDS             2183..2551
                     /gene="rplL"
                     /locus_tag="VQ548_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HET2654073.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKTKLEEAGASVTLK"
     gene            2738..2908
                     /locus_tag="VQ548_001219"
     CDS             2738..2908
                     /locus_tag="VQ548_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654074.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            2908..3156
                     /locus_tag="VQ548_001220"
                     /pseudo
     CDS             2908..3156
                     /locus_tag="VQ548_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            3170..3510
                     /locus_tag="VQ548_001221"
                     /pseudo
     CDS             3170..3510
                     /locus_tag="VQ548_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3503..3883
                     /locus_tag="VQ548_001222"
     CDS             3503..3883
                     /locus_tag="VQ548_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET2654075.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            3896..4039
                     /locus_tag="VQ548_001223"
     CDS             3896..4039
                     /locus_tag="VQ548_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654076.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            4132..4719
                     /locus_tag="VQ548_001224"
     CDS             4132..4719
                     /locus_tag="VQ548_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2654077.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHTGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF"
     gene            4921..5058
                     /locus_tag="VQ548_001225"
     CDS             4921..5058
                     /locus_tag="VQ548_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HET2654078.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            5237..7846
                     /locus_tag="VQ548_001226"
     CDS             5237..7846
                     /locus_tag="VQ548_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HET2654079.1"
                     /translation="MDYNFNLEHPFFFTNNDYSTDTSIKYQVSLPFNWHEVMNNDEWV
                     YQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGK
                     LVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFR
                     PSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFI
                     IDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSEKLASECKALKILN
                     EWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIV
                     EKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIIDWEQAVFSNDEKVVHKVAAPGF
                     RAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNYVSQTRIEGKKLFESLGYTREH
                     IDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIESEQDIQDFIIKLLRGFTLTYG
                     QWRKEFQSRFFPVHYYGLNFNQGIAFSDLAILWSYQQLAKKVKNFKFDDYYEIRTQVI
                     NEAVNNFKKSSLSGLFDGKIGTIWLIYEFGEIDRAVELFTTHFIEIFENSQNKNLYSG
                     QAGILLVGLYFLSKGEIDNKLGEEILIRLREYTLNYIENPETFCKVGASDVQSNDPYE
                     NFGGLLYGHAGVAWLFGEAYKLTGESIYKNGLELAVDKELVAYKVDSNNSLQYSQGHR
                     LLPYLATGSAGLLLLINRNKEILSSKYLKYLTSLERATDVVFCVLPGLFNGFCGLEVA
                     NNIYSDIDDNFSGQKKLIEQLYRYLCVIEEGFVIAGDNGLKITTDIASGFAGVAIGLV
                     SIMDNKLTILPQI"
     gene            7879..9819
                     /locus_tag="VQ548_001227"
     CDS             7879..9819
                     /locus_tag="VQ548_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HET2654080.1"
                     /translation="MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWY
                     QFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDV
                     RISSDESYIVLVVSSLRSTNLIGIKKYTMEELFIIEDISVESSFYLGKFGVMYTRSKE
                     YGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFD
                     RTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGLSSTEEKKDQLILRETSSGDRVSIT
                     IPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYEN
                     SFSDRVLLFLERRTFYEKILSFDLIENTLKTEFERPIIKSNNTKYFSKVIWTKKDSYD
                     VSIPISLFWKSEDTDELPRRKKCILSVYGAYGKNDNSDLDEIMLSIIDAGFIYAIVHV
                     RGGGYLGGEWYRSGKALNKWNSIRDFIEGVNYLRENDVIDSKRLGLITSSAGGIIAGA
                     VLNEEKNLLQSILLFSPFINPYDTLQNPNDPLSKTEIAEWGDIRDPEVKAYIKSYSPM
                     QNIEKARDSNTVIVNILGEKDPYINNNEVIEWSKKLNSIGVKSLLYLNKAAGHGGFTP
                     SDVLLMIDTLNYFFEEVGRNNL"
     gene            9816..11423
                     /locus_tag="VQ548_001228"
     CDS             9816..11423
                     /locus_tag="VQ548_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2654081.1"
                     /translation="MNYLKFIKKTKLILMGILIFLSSFNGVLLSGIIVYAGSLNQTSS
                     FSDVLRFGAISILGWSAIYISNYYLEVTEASITKDINVKIKQGYFREQYLSSEMVKDY
                     SSIISVLSNDLRLIEENYFRQIFEIISSILLFIVSLSFMLYLNFLVSIIFIVLSALPI
                     IVPVFMKKMLSNSANEYSNSNAEYTHIIKEIFNGFKTLKSYSVTKEIISLSDKKLDKL
                     EDSTFNLKRSEVLSKLVAVLISGFCFLVPLVVGCYFVIYHKSLSFSELIGIFLANDKV
                     LGPIQSIAYSLNKINTTKDLRKPFLKYLSGEKNFIDAEHDNNGLYTSSIDEIHMKDVV
                     YSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLINGSLKPQKGYVNLLSHGKKS
                     SDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVLKKVNLYEELEKIDILNYQC
                     GENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDNDNSNSIHDILFNLGISFIE
                     VSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            11438..12178
                     /locus_tag="VQ548_001229"
     CDS             11438..12178
                     /locus_tag="VQ548_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2654082.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            12181..13500
                     /locus_tag="VQ548_001230"
     CDS             12181..13500
                     /locus_tag="VQ548_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654083.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIASKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLEDVLIDDMNLLGLILPNFIVSIILFILIFITKSSYFIFKNAKIIS"
     gene            13634..13771
                     /locus_tag="VQ548_001231"
     CDS             13634..13771
                     /locus_tag="VQ548_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HET2654084.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            14067..15418
                     /locus_tag="VQ548_001232"
     CDS             join(14067..14508,14508..15418)
                     /locus_tag="VQ548_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET2654085.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSISLDYALPNQGMLSFWPAQYKKN
                     GYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENERLRTEVAYPKKVKRVRGKGRS
                     PRARKAETVREMVSGGFRLDFLLETARLARSTYYYQLKQLDGVDKDKEIKTEIQGIDN
                     EHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLTARIRRKRKYSSYQGEIGKKAE
                     NLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPVLDGFNSEIIAYHLSTSPNLEQ
                     VKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRKGNSPDNGMME
                     SFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNNKRIKVKLKGLSSVQYRTKSFG
                     "
     gene            complement(15653..16261)
                     /locus_tag="VQ548_001233"
     CDS             complement(15653..16261)
                     /locus_tag="VQ548_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HET2654086.1"
                     /translation="MQIKFIDKVSNLIMLNLLYVASVVTVIAIGSGESALIATLIKIV
                     RHEESYPYRDFANSFFKDYWKNLGAALISNLPILILLFSLFFLPYIPLPIYIISILRH
                     IGVIYIILHLIATTFLIPLIGRYNNTLKNSLHNSIMLAYKHFFIAVLIRIIEIIPVLL
                     FFILQNQLLVWITLMIFILPSITKYANAFLYNFIFSKYEKLN"
     gene            16427..16597
                     /locus_tag="VQ548_001234"
                     /pseudo
     CDS             16427..16597
                     /locus_tag="VQ548_001234"
                     /inference="COORDINATES: protein motif:HMM:NF013577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
     gene            16586..17197
                     /locus_tag="VQ548_001235"
     CDS             16586..17197
                     /locus_tag="VQ548_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2654087.1"
                     /translation="MTKDILELESQKMSSDTFIDEIKNNYLSIVESTRKLIDGRQIEL
                     AIKLIREANQILMIGVGSSGNAAREFESSLLRIGIISKTVIDTHFQLMHTALLKDNDL
                     IIAFSLSGSTKEVEETLLNAKRKNVKIISITNYSSRNIAKLSDCVLLTSKKESYLEGG
                     SLMAKASQLFIIDVICTRLSLINYEDTICKKEEIASLLSNKVE"
     gene            17914..18600
                     /locus_tag="VQ548_001236"
     CDS             17914..18600
                     /locus_tag="VQ548_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2654088.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMAAISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            18601..19533
                     /locus_tag="VQ548_001237"
     CDS             18601..19533
                     /locus_tag="VQ548_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2654089.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFFFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            19544..20473
                     /locus_tag="VQ548_001238"
     CDS             19544..20473
                     /locus_tag="VQ548_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2654090.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPGAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLRNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            20487..21926
                     /locus_tag="VQ548_001239"
     CDS             20487..21926
                     /locus_tag="VQ548_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654091.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHTGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            21995..23572
                     /locus_tag="VQ548_001240"
     CDS             21995..23572
                     /locus_tag="VQ548_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2654092.1"
                     /translation="MVKLNKVLKGSVAFLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDETLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSQHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKSFDWQPLVYPEINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            23632..25092
                     /locus_tag="VQ548_001241"
     CDS             23632..25092
                     /locus_tag="VQ548_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET2654093.1"
                     /translation="MYDVVIIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIKKGGTVFNSMEELMNVNDFYQITIPYQPE
                     VYESVLTDMLIESKVDILLNVEVNNIIYDSKNIKSLEILSNQEVKLIDSKVFIDATGN
                     ATIASASGADVYEKNSSYGCLMRVGGVDISKTIEHIEKTKQWNYIEGYNQWLEEVLAN
                     RKYRATGAVLKDPVSYDHAPMLSKDDHFMNDEKWNYIKERWEKFRFIYTLEVSLFRNE
                     LKKAVESGDFNFEIYHDDKSGVTMNGDGISYGSWGQNVALINVAKAFGFNPKYMEDES
                     HANILSRKYNLTFLSFLKKYVPGFENSFILDQGTRATNRSCRHIDNSSMMDEILDFPM
                     YTFKTMYSYQTPKEITYKSIVGGKLNNLFVIGKGAYQSESFRSQISCMLMGISSAAAA
                     KTIIEDKSNTLNINRDLFKSNLDILFTWEFSNWITD"
     gene            25114..25569
                     /locus_tag="VQ548_001242"
     CDS             25114..25569
                     /locus_tag="VQ548_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT domain-containing protein"
                     /protein_id="HET2654094.1"
                     /translation="MNDTNKNQYFVYEFDTSFVEMSYSQFFEGYCILFSKEPYPSLSD
                     MPMEFRKEFLMEMSILGDAMLEVLNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRK
                     TVVHRYDSSVFSNPEFEFTIEKHGPIIKKLRSAIDRHYREYQQLLDDSN"
     gene            25656..26061
                     /gene="cdd"
                     /locus_tag="VQ548_001243"
                     /pseudo
     CDS             25656..26061
                     /gene="cdd"
                     /locus_tag="VQ548_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221146.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
     gene            26074..26523
                     /locus_tag="VQ548_001244"
     CDS             26074..26523
                     /locus_tag="VQ548_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2654095.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDILKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDVHYLLNGEETILYNFLSQMELSEYKVDDDWQ
                     QMNGTALFSIKLKKDMLLLLEPNDAHRTGLLVEEPLNIKKVVFKVKI"
     gene            complement(26635..27194)
                     /locus_tag="VQ548_001245"
                     /pseudo
     CDS             complement(26635..27194)
                     /locus_tag="VQ548_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         9463 a         3747 c         5251 g         9030 t
ORIGIN      
        1 agatagaact gacgaagtca gtaaccacac ctacggcaaa gtgaatctga agtggtttga
       61 agagagtaca acttgtcttt tagaaaagga gcctataatg aaagtctttc agcatgtaaa
      121 tatcgtgact tgtgatcaag atttccatgt ttatcttgat ggaatcttag cagtcaagga
      181 ttctcaaatc gtctatgtcg gtcaagataa gccagcgttt ttagagcaag ctgagcagat
      241 tatagactat cagggagctt ggattatgcc tggtttggtc aattgtcaca cccattctgc
      301 aatgacaggt ctgagaggga tccgagatga cagcaatctc catgaatggc tcaatgacta
      361 tatctggcca gcagaatctg agtttactcc cgacatgact accaatgcgg tcaaagaagc
      421 cctgacagag atgctccagt caggaacaac aacctttaac gatatgtata atcccaatgg
      481 tgtggatatc cagcaaattt atcaggtggt gaaaacttcc aagatgcgtt gttatttttc
      541 tccgactctc ttttcttcag agacagaaac aactgctgag actataagca gaactcgatc
      601 catcatagac gaaatcttaa aatataaaaa tccaaatttc aaggttatgg tagcacctca
      661 ttctccgtat agctgcagta gagacttgct ggaagcgagt ttggaaatgg caaaagagct
      721 aaatattccg ctccatgtcc atgtggcgga gaccaaggag gagtcaggaa ttatcctcaa
      781 acgatacggc aaacgccccc ttgcttttct tgaagaactg ggttatttag atcatccgtc
      841 cgtatttgct cacggggtcg aattaaacga gagagaaatt gaacgcttgg catcttctca
      901 agtggctatc gcccacaatc ctatcagtaa cctcaaactg gcatcaggaa ttgctccaat
      961 tatccagatc caaaaagcgg gagtagcagt cggaattgcg actgactcgg ttgcttccaa
     1021 taacaatcta gatatgtttg aggaaggaag gactgcagct cttcttcaga agatgaaaag
     1081 tggggatgcc agccagtttc caatcgaaac agctctcaag gtactgacaa tcgaaggggc
     1141 taaggtcctt ggaatggaaa atcagatagg aagtctggaa gtcggcaagc aagcagattt
     1201 tctggtcatt caaccacaag ggaaaattca tctccaacct caggaaaata tgctgtctca
     1261 cctggtttat gcagttaaat ctagtgatgt agatgatgtt tatatcgccg gagaacaggt
     1321 tgttaagcaa ggtcaagtcc tgacagtaga actttaaaag aaaaatcacg aaaaatttta
     1381 aaaaaagttt gcaaaaatct tgcattcttt ttttgactat gctatactta tatacggttt
     1441 aaaaaaactg cctaagacag taggggagct cgactcataa atatcctacc gaggacaaga
     1501 cgtatcatgt aaaaagaagc gtattgtact ttcgtgtcta ggtttgggcg cgtttttctt
     1561 tttgaaaaat tccccaagca aaataattac ggaggtgaac acactaatga gtgaagcaat
     1621 tattgctaaa aaagcggaac tagttgacgt agtagctgaa aaaatgaaag ctgctgcatc
     1681 tatcgtcgtt gtagacgctc gtggtttgac agttgagcaa gatacagttc ttcgtcgcga
     1741 gcttcgtgga agcgaagttg agtataaagt tattaaaaac tcaatcttgc gtcgtgcagc
     1801 tgaaaaagct ggtcttgaag atcttgcatc tgtatttgtt ggaccatctg cagtagcatt
     1861 ttctaatgaa gatgttatcg caccagcgaa aatcttgaac gacttttcta aaaacgctga
     1921 agcacttgaa attaaaggtg gtgcaatcga aggcgctgtc gcatctaaag aagagattct
     1981 tgcacttgca actcttccaa accgcgaagg acttctttct atgctccttt ctgtacttca
     2041 agcgccagtg cgcaacgttg ctcttgcagt caaagcggtt gcagaaagca aagaagacgc
     2101 ggcttaatct taagctacac agcgtagcct agctacgaaa aaaactatta taaaatttaa
     2161 aacttatttg gaggaaataa caatggcatt gaacattgaa aacattattg ctgaaattaa
     2221 agaagcttca atccttgaat tgaacgacct tgtaaaagct atcgaagaag aatttggtgt
     2281 aactgcagct gctcctgtag ctgttgctgc agctgatgca gctgatgctg gtgctgctaa
     2341 agattcattc gacgttgaat tgacatctgc aggcgacaaa aaagttggcg ttatcaaagt
     2401 tgtacgtgaa atcactggtc ttggtcttaa agaagctaaa gaacttgttg acggtgcacc
     2461 agcacttgtt aaagaaggcg ttgcaactgc agaagctgaa gaaatcaaaa ctaaattgga
     2521 agaagctgga gcttcagtta ctcttaaata atagagtatc gcaatttgat tgcggaatcc
     2581 ctatttacca gtctttgaga gcgataagcg attgatagaa actgataaat tgatttggtt
     2641 tcctgccaaa aattctttgg caggattttt gttttaataa actttcgggg gtagacacta
     2701 gattgtctac cccttttttt gtgtttcgga ggtaattatg caaaaggaag gacagtcatc
     2761 acgtcaattc gtgaagagtc atctcatgac tatcatggga gttgatattg taaaagcaac
     2821 tcagttagtt gatgaaatgg aacaagtagg tttaatccga tttgatgaat ttggaaatgt
     2881 tggaatttta gtcttggagg gacaataatg aagtgtatta ccgctaatca atatcagaca
     2941 tcagagcgtt attataagct ccccaaactt ttatttgaga gtgaacggta taagaatatg
     3001 aaactggagg ttaaggtggt ttactcagtt ttaaaagatc ggttggagtt gtctttgagc
     3061 aaaggttgga ttgatgagga tggggctatt tatttgattt attccaattc aaatttgatg
     3121 gcacttttag gctgttcaaa gtcaaaatta ctctccatgt gagtttgaag tgacattttt
     3181 agatgattac cataaaaaac ataactaccc actattttac gaatcctatc ttcaaaacgt
     3241 tatggaattc cttgaaagtc aagacataaa gaatggggtt gatgcctttg tagatgatca
     3301 tcaaaatctc gtttttgttt tatatggaca aggctatcga gccgagggaa aagagggaat
     3361 acttacaacc caagtaactg taaaagctta tgatgaagac aagaaaccga ttaacttcgc
     3421 aaatttatta gattccttaa tttattagat tccttaatcg tgtcagaata tcaaatggaa
     3481 ccgaatcttt gggaggtctc ccatgattga tctctatcta agtaaaaata gacaaagaaa
     3541 tcaacttctt ttagatttct tccaaaacta tggcatagag gtatcttgtc attcagtttc
     3601 tgaaatgaca aaggacaaat taattgagat gatgagctat tcttcagatt gttttgagtt
     3661 tttatctccc aatttattac gatttaagaa ccgtgacaat ctaagattaa cggatttcgt
     3721 tgagataatt ttaaaaaatc ctgaactaac catcagactt cctcttgcgg tttcaaataa
     3781 gcgagtttat ccaagtctga atttggaaga ggctagagct ctattgccaa gagatacgaa
     3841 acaattgatt tacatggcgc aaacacatta tttatctaac taaaggagaa gcaatatggc
     3901 tgaacgattt tgggagaact tgtccattat tttggctgaa agaaatatca gctggattga
     3961 gttaaccaga aaaatgtttg cgggagagtt tcactatcca agtgaattga atcgtttgta
     4021 tcaaaagatt cgccactaga agatggaaca atgaatgcct caaagtccat gggtagaaag
     4081 gattgtgcag gtattagatt tagattatga agatttattt cggaggtaac tatgaaaaga
     4141 ataattccag tttatatatt ccaacaagta aatgtcctat tggtatctct atacttattg
     4201 aaatttcttt gtatcggtga gttaactata ctacagattc tctatggttc gtcactcatt
     4261 tcttttttat ggatgtatgg ccaacgcaaa caagcgcata aggtcaatat gaaatctagg
     4321 atgaaatggc ttggtgttga atttgttagc ctactgatta taagtctatg ttttagtctg
     4381 attcatgctc aaggaagcac gaatcaagca aacttaattg gccttcaaca tcaaattcct
     4441 tggttttcat ttttattgtt cttaatcaat gcgagtatgg ttgaagaatt tctgtatcga
     4501 gaaattttat ggaatttggt cagaaaatta gatatcagag ttgctttgac aagtgtttta
     4561 tttgccttag cacatcatac aggaaccatt ctagcttggt gtttgtatgt ttcacttggg
     4621 atgtttttag gtatggtgcg ctataaatct gacttatggg gcagtatggg actacatttg
     4681 gtgtggaacc tactagttta tagtttgctg cttttttaaa ataggtgacc tgatttttag
     4741 gtaacttcta aaactaactt ccagttttgg gagagagatg gaagttactt tgaaaagtta
     4801 cggaaacatt attttctatg tgacaacatt gtataattgc ttgcatttta ctggtggaga
     4861 gagtataatg agggtggata aagtacttaa tcccaaaaat ttaaatagga ggagctagct
     4921 atggcagaag aagtattaaa tcttcaatta gtatctgttc aagttgacga aacagatgaa
     4981 gttgatggaa tgcgatttag tacattcagt acaaatcgtt gcggtaactg gagtgctttt
     5041 agttgggaaa attgttaatt catttaaatt gtaaacttta gagattctct ggagttatgg
     5101 atgtcgttcc aatatgtgca cgttggaatg ttagtgctta tatggggaga atccaaagga
     5161 ttctcccttt ttatttaaat aagtctgtct agctatagat atattaagtt tgataaaatt
     5221 tcttggagat tttgttatgg attataattt caatttggag catcctttct ttttcactaa
     5281 taatgattat agtacagata ctagcataaa gtaccaagta agtctgcctt ttaattggca
     5341 cgaagtaatg aataatgatg agtgggttta tcaataccct attggaaaat ttgttgaaag
     5401 acaagggtgg aaaatacaca ttagttcaga gtataacagt tcacatgaat tgttacaaga
     5461 tgtagcaaaa atttgccatg aaatgcgaat tccatttaaa catcttagta cagaagacaa
     5521 atttatcatg cgaaacggga aattggttag tcgaggattt tctggtaaat ttattacatg
     5581 ttatccaaat caaaatgaat tagagtcggt tttgcaaagg ttagaaagtg ccttaaagca
     5641 atataatggg ccatatattt taagcgataa acgttgggat gaagcaccaa tatatctgag
     5701 gtatggtgtg tttaggccgt caagggatga tgaaaagaag gttgctattg atgaattaat
     5761 tgttggcgat gaagttgtta aagatgaacg tttaccagta tttaaaattc caaaaggtat
     5821 agtgccccct gactttttga ataaatggct tgacaagaaa gataaaaaac agggagactt
     5881 tccctttatt atagataatg caattagatt ttcaaacagt ggtgggatat ataatgctag
     5941 gctaaaagaa gatgggaaaa aaataatttt aaaagaggct agaccgtata caggtctagg
     6001 atttgatggt acttattctt cagagaaatt agcttcggag tgcaaagcac taaaaattct
     6061 aaatgaatgg agtgagacgc ctaaaatata ctggcacggt aagatctggg agcacacctt
     6121 cttaggaatt gaacatatga agggcgttcc actaaataga tgggttacca ataattttcc
     6181 tttatatgaa gttgttgata agaccaaaga ttatctattg agagtttcaa agatagtaga
     6241 aaaactcatc gatttaacga ataagtttca ttctgaaaat gtatatcatc aagatttaca
     6301 tttaggaaat atcttggtta aggatgaaga tgagattagt ataatagact gggaacaggc
     6361 tgtcttttca aatgatgaaa aagttgtaca taaagttgca gcccctggtt ttagagcatg
     6421 gcgagaaaca cttcccagtg agatagattg gtatggtatt agacaaatag ctcattattt
     6481 atacatgcca ctagtaacta catcggattt gacatacaac tatgtaagtc aaaccaggat
     6541 agaaggaaaa aaactatttg agtctttggg ttatacaaga gaacatatag attatgtaga
     6601 aagtttattg tcatatctag attctaaatg tccacagatt gagaatattt ccaggaaaaa
     6661 agttttaaaa cccatgcatg agattagaac tatcgagagt gagcaagata tacaagattt
     6721 tattataaaa ttattgagag ggtttacgct aacttatgga cagtggcgta aagaatttca
     6781 atcaagattc ttcccagttc attattatgg tctgaatttt aatcaaggaa ttgcgttttc
     6841 agatttagct atcctttgga gttatcaaca actagctaag aaagtaaaaa atttcaagtt
     6901 tgatgactat tatgagattc gaacacaggt tattaatgag gcagtaaata attttaagaa
     6961 atcgtccctt tctggtcttt ttgatggtaa aattggtaca atctggctca tttatgaatt
     7021 tggggagata gatcgggcag ttgaactttt tacaactcat tttatagaga tatttgagaa
     7081 ttcacaaaat aaaaatttat atagtgggca ggctggaatt ttactggttg gactgtattt
     7141 tcttagtaaa ggggaaattg ataataaact aggagaagaa atactaatta ggcttagaga
     7201 atatacttta aattatatag aaaatccaga aactttttgt aaagttggcg ctagtgatgt
     7261 tcagagtaat gatccttatg agaattttgg tggattacta tatggtcacg caggggtagc
     7321 ttggctcttc ggtgaagctt ataaattaac tggtgaaagt atctataaaa atggtctaga
     7381 attggctgta gataaagaat tagttgctta taaagtagat agtaataatt cattgcagta
     7441 cagccaaggt catagattac taccatatct agcaactgga agtgctggcc tgcttttact
     7501 tattaataga aataaagaaa tcttgtcaag caaatactta aaatatttaa cttctttaga
     7561 gagggcaact gatgtagttt tttgtgtatt accaggttta tttaacggat tttgtggtct
     7621 tgaagttgct aataatatat atagtgatat cgatgataac ttttcaggac aaaagaaatt
     7681 aattgaacaa ctttatagat atttgtgtgt aattgaagaa ggatttgtta ttgcgggaga
     7741 taatggttta aagataacaa cagatattgc ttcgggattt gcgggtgttg caattggatt
     7801 ggtatcaata atggataata aattgacgat tcttcctcaa atataatatt tagataccat
     7861 tattaagggg tcatacttgt gaatcagagt aatgaaatat ttttaaatac aatacaggaa
     7921 aaaacacact ataagaggtc tatctcttca tcatttcagg aattaaaaaa atggaattct
     7981 ttgatattta ggagagggcg atattggtac caatttgata attggagtat acccaatact
     8041 ggtgtaataa aggaatggta tgtcgaagat aatgactgga ttcctaaggt tagttcttcc
     8101 agtttagaca attcaaattc acttaaaatt gtctttgatg tggaaaaata tactttgcca
     8161 gatgatagta tcttacagga tgttaggatt tcatctgatg agagttatat agttttggtt
     8221 gtatcctcac tgcgtagcac taatttaatt ggaataaaaa aatatactat ggaagagtta
     8281 tttatcattg aagatatttc agtagaaagt tcgttctatt tgggtaaatt cggtgttatg
     8341 tatactcgct ccaaagagta cgggaggcca agtaagttat tctataaatc ttttgatagc
     8401 tttacagaag aggaactgtt tgaagaaaac gaatgctctt ttcgattaaa aatagtccac
     8461 attgatagca ataattgttt tgtaaagtca gtagactttc agaaaggcag gatttttcta
     8521 tacagtttcg accggacggg ttttgttaga cactcttaca cagaaacggt agccccaaca
     8581 cctagagata tcgctctatt tagtacagaa aaagcacagt actttcttgg gctctcttca
     8641 actgaagaaa agaaagatca actaattcta agggaaactt cttcgggaga cagagtttct
     8701 attactatac catatcaaga tagggctaga agagttcact gtataggacg ttatatcctt
     8761 ttagactgtt caaacgcagc gaattccgtc ttttatcttg ctacatttaa aaataatagt
     8821 ttgagggagt tgagtgttaa taagataaca tttgatgaaa agacaacact ttatgaaaat
     8881 tcattttctg atcgtgttct tctgttttta gagaggagaa ctttttacga aaaaatactt
     8941 agttttgatt taatagaaaa tacattaaaa actgaatttg aaagacccat cataaaatcg
     9001 aataatacta aatatttttc taaggtgatt tggactaaaa aagacagtta tgatgtaagc
     9061 ataccgattt ctttattttg gaaaagtgaa gatacggatg agctcccaag aagaaaaaaa
     9121 tgtattctaa gtgtctatgg ggcttatggt aagaatgata attctgattt agatgaaatt
     9181 atgttatcta taatagatgc aggttttatt tatgctatag ttcatgtaag aggtggaggc
     9241 tatttgggtg gtgaatggta tcgctcagga aaggcgttaa acaaatggaa ttctatcaga
     9301 gattttattg agggagtaaa ttatttaagg gaaaatgatg taattgacag taagcgatta
     9361 ggtttaataa cttctagtgc aggtggaata attgctggtg cggtgttgaa cgaggaaaaa
     9421 aatttattgc aaagcattct cttattttcg ccatttataa atccttatga tacacttcag
     9481 aatccaaatg atcctctttc taagaccgaa atagcagagt ggggagatat tagagaccct
     9541 gaagtaaagg cttatataaa gtcatattcg cctatgcaaa atattgaaaa ggcacgagac
     9601 tcaaatactg ttatagttaa tattttgggt gagaaagacc catatattaa taataacgaa
     9661 gtgatagagt ggtcaaagaa attaaattct attggagtta aaagtttgtt gtatttaaac
     9721 aaagcagctg gtcatggagg ttttactcca tcagatgttc tcttaatgat tgatacttta
     9781 aattatttct ttgaagaagt gggaaggaat aacttatgaa ttatttaaaa tttataaaaa
     9841 agactaaact tatattaatg gggattttaa tatttctatc ttcgtttaat ggtgtcttgc
     9901 tctcaggaat tattgtatat gcaggtagtt taaatcagac ttcctcattt tctgacgttc
     9961 taagatttgg tgctataagt attctgggtt ggtcagcaat ctatatatca aattactatt
    10021 tagaagtaac ggaagcatca ataacgaaag atataaatgt aaaaattaaa caaggatatt
    10081 ttagagaaca gtatctttct tctgaaatgg ttaaagatta ctcatctatt atttcagttt
    10141 tgtcaaatga tttgagatta atcgaagaaa actattttag acaaattttt gaaataattt
    10201 cttcaatatt gttgttcatc gtctctctaa gttttatgct ttatttaaac ttcctagttt
    10261 caataatatt tattgtatta tcagcattgc cgattatagt acctgtcttt atgaagaaga
    10321 tgttgtctaa ttcagctaat gagtactcta acagcaatgc agagtatact cacataataa
    10381 aagaaatttt taatggtttt aagacattaa aatcttattc tgttactaaa gaaataatta
    10441 gtttgtcgga taaaaagttg gataaactag aagattctac ttttaatttg aaacgatcag
    10501 aggttctttc aaaattggtt gcagtactaa tttcaggttt ttgctttcta gttcccttgg
    10561 ttgtaggatg ttattttgta atttatcata aaagcctttc ttttagtgaa ctgataggta
    10621 ttttcttagc aaacgataaa gttttagggc cgatacaatc aattgcctat tcattaaata
    10681 agataaatac aaccaaagat ttaaggaaac cgtttttaaa atacttaagt ggagagaaga
    10741 attttataga cgctgaacat gataataacg gactgtatac ttcatcaata gatgagatac
    10801 acatgaaaga tgttgtatat tctattacac cagaaaataa attaagtatt gacttctcat
    10861 ttaagtcacc atttagggta ttattaacag gaacttctgg tagtgggaaa acaacgattt
    10921 taaatttaat taatggttct ttaaagccac aaaaaggtta tgtaaatttg ttatcacatg
    10981 ggaaaaagag ttcagattca ataccaacag ttgatcagac accatatatt tttgacacta
    11041 ctattcgtga gaacgtaact ttatttcaaa atgaatattt ttcagatgat cagataattg
    11101 aggtgttaaa aaaggtaaat ctatatgaag aattagaaaa gatagatata ctaaattatc
    11161 aatgtggtga aaatggtagt aatttgtctg gaggtcaaaa acaaaaaata gctttagcta
    11221 gagctctgat tagaaataat aaagtgtact tatttgacga aatatcagct aatttagata
    11281 atgataattc aaattccata catgatattc tgttcaattt aggtatttca tttattgaag
    11341 tttcacatca ttatgactta aatgacaaga gatacactga tatatataaa ttggaaaatg
    11401 gaacactttt caaaattaag tgattggagg caagaatatg gataaagatt atatattaaa
    11461 agtgaaaggg ctgtatcatc aatttttact aggaaataat aaaacgttgc aagtgctgaa
    11521 aaatgtttct ctttctgctt cgagaggaga atttataagt attctaggaa ttagtggttc
    11581 tggaaagtca actttattaa aatgtatttc tagtttgctt gaaccaacaa gtggggaagt
    11641 aattttaaat ggaatcaacc cctataaaat cagaaatgca aaattgtcaa gtataagacg
    11701 taacgaagta tcttttatat ttcaagcata caatttaata ccttccctgc cggtaataga
    11761 aaatatagca cttcctttgc gattatcaca aaaaaaatta actattaaaa atgtagaaaa
    11821 cttactcaaa agaatgaagt ttaatgctgg cttaaacgat tttgttggaa ctctgtctgg
    11881 tggagaacaa cagaaggttg ctatagctag agcggttatt gctgatagtg atataatatt
    11941 tgctgatgag ccaactgggg ctttagacag cgtttctcgt gaagtaattt ttgaattatt
    12001 gagagagtta gtaggggcgg gtaagtgtgt aattatggta acgcacgata tagaattggc
    12061 ctcgaaaact gatcgtgcat taatattgaa agatggaaaa attttcaaag aacttcatag
    12121 acctagcggg gaagagttgt ataaaatctt agaggtacaa tcaactacgg aggaatagag
    12181 atgctcagat tagtttacta tcaattttta cataataaga aacaatggtt aggcgtttca
    12241 ccagtaattt ttgtttcgag tttagttatg ggattggctg ttaatggggt aattaatgtt
    12301 gagaataatt cgcaagtatt tgtcggactt ccagatccta aaccaatttt tatgtttccg
    12361 atagtattcg gaggagtaac attattcttt gtgctctcta acataataaa tatgttggtt
    12421 gaaattttta gagatgatta cgaacttctg gaggtgttgg gagcaagtct ccttcaacta
    12481 tcatttcttg tggggggaca gatttttatc atttcctcga ttattagttt tattgcatat
    12541 ctatgctcta tatttgttac gtcaaattat tattattttt tacaatactt tttcggggaa
    12601 aatatattac ctgatatcca atttcaaacg agtgctgttg gatgtatcat tacagtagtg
    12661 ttgatttcat ttttagcctt tctaagtggt tgcttttata cgttcaagaa gattagaaat
    12721 aggaagagtt ctaaaataag gcatgttctt tcaatagtaa aaagaatact gctattggct
    12781 ggttttagtg ttatctggtt gctttctttg caacaaattt tccaagatag cacaatttta
    12841 gcgaaggccc agataatatt caatattgta atcttagata ttgtgattat ttatcaatta
    12901 tctcctttta tacagtcatg ttttatcaaa ctactttcta taattatatt tagaaataat
    12961 tttatgttca ttgcttcgaa gtggaattta ctatatcgta agccttatat aaaatctatc
    13021 agtgctgcaa ttacaggagc tatattacta atttctagtt ttcaaatgat ttctcagaat
    13081 atactatctc aatttcaaga tgacagtgat ttagagctaa aagtggcatt tattgtctat
    13141 gtaggagcac caattttgat agtacttgca aatattattt caattgcatt tttgtcatcg
    13201 catcaagaaa ggattgagat tcagcaattt gaaattttag gaacttctaa ttaccagatg
    13261 gttaagatta aagttggtga ggctatattt ttgacatttg ttacttcatt aattgcattt
    13321 ttacttaaca ttaaaattat ggctttaata tactactctt tagaggatgt tttaatagat
    13381 gatatgaatc ttttggggtt aatacttcca aattttatag tgtctattat tttatttatt
    13441 ttaatattta ttactaaaag ttcctatttt atctttaaga atgcaaaaat tatttcttaa
    13501 aaatttgtaa gttttcgcta tataaaatag ttaaatctat tttgtatcat tgcttgcatt
    13561 ttactggtgg agagaatata atgagggtgg ataaagtact taatcccaaa aatttaaata
    13621 ggaggagcta gctatggcag aagaagtatt aaatcttcaa ttagtatctg ttcaagttga
    13681 cgaaacagat gaagttgatg gaatgcgatt tagtacattc agtacaaacc gttgcggtaa
    13741 ctggagtgct tttagttggg aaaattgtta attcatttaa attgtaaact ttagggattc
    13801 tctgaagtta tggatgtcgt tccaatatgt gtacgttgga atgttagtgc ttatatgggg
    13861 ggaacagaat cctctcttga ttgaagacaa gttagccatt aggctggttt gtctctttgt
    13921 caactgtagt gggttgatat aatagtatta gtgagtggga taaaagtttc atttagttta
    13981 ttcagtacaa atttaacggg tcaagattta ttgaactgca ccccaatagt tagacagaaa
    14041 aaatctaact tttggggtgt tttattatga aattgagtta tgaagataaa gttcagatct
    14101 atgaactaag aaagcaagga caaagcttca aacagctttc aaaaagattt ggtgtggatg
    14161 tttctggtct aaagtacatg gtgaaattaa ttgaccgtta tggcatagaa atcgttaaaa
    14221 aagggaagaa tcgtcactat tcttctaaat tgaaacaaga aatgatggat aaagccttac
    14281 tggaaggttg ttcacaaaga agtattagtc ttgattatgc cctcccaaac caaggaatgc
    14341 tttcattttg gccggcacaa tacaagaaaa acgggtatac tattgttgag aaaacaagag
    14401 ggagaccagc taaaatggga cgtaaacgga agaagacttg ggaagaaatg acagaactag
    14461 aacgactcca ggaggagaat gaacgcttac ggactgaggt ggcctaccta aaaaagttaa
    14521 aagagttaga ggaaagggac gaagccctag agcgagaaag gcagagacag ttagagaaat
    14581 ggtttcagga ggatttcgac tagattttct tcttgaaaca gcacgtttag ctcgctcgac
    14641 ttactattat cagttgaaac aactggatgg ggttgataaa gataaagaga ttaaaaccga
    14701 aattcagggc attgataatg aacataaagg caactatggc tatcgtcgaa tccatttaga
    14761 actaaggaat cgtggttttg tggtcaatca taagaaagtt caacggttga tgagaattct
    14821 tggtttaacg gctcgaattc gccgtaaacg gaagtattct tcctaccaag gagagattgg
    14881 caagaaagca gagaatctca ttcaacgcca gttcgaagca tcgaggccaa tggaaaagtg
    14941 ctatacagat gtgacagagt ttgccattcc aaatagcaca cagaaactct atttatcacc
    15001 agttttagat ggttttaaca gtgaaatcat tgcttatcat ctttctactt cgccaaactt
    15061 agaacaagtg aagagtatgt tagaacaggc ctttacagag aaatactatg agaatacgat
    15121 tctccatagt gaccaaggct ggcaatacca acacgattct tatcatcggt tcctagagag
    15181 taagggaatt caagcatcca tgtcacgcaa gggcaacagc ccagacaacg gcatgatgga
    15241 atctttcttt ggcattttaa aatccgaaat gttttatggc tatgagaaga actttagatc
    15301 tttagaaaac cttgaacaag ctattgtgga ctacattgat tactacaaca acaaacgaat
    15361 taaggtaaaa ctaaaaggac ttagttctgt gcagtacaga actaaatcct ttggataaat
    15421 tatttgtcta attttttggg gtcagtacag tattaaatac catgatctta tgcgttttat
    15481 aataaaaaat ctgttcttgt tttattttta gaaaatttac taaagactaa aaatattatg
    15541 aataatttaa aaaatagtca ggttatatag ttttttgaaa ttaaaattat tttatcgttg
    15601 aaattagtta aaaattttta taaaatcaag atgcaaggct atgagatgtt ctctagttta
    15661 atttttcata cttcgagaat ataaagttat ataaaaatgc attagcatat tttgttattg
    15721 agggaagtat aaaaatcatt aaagttatcc aaactagtaa ttgattctgt aatataaaga
    15781 agagtagaac tgggataatt tcaataattc taataagaac ggcaataaaa aaatgtttat
    15841 aggctaacat gattgaattg tgtagagaat tttttaaagt gttattatat ctaccgatta
    15901 aaggaattag aaatgttgtt gctattaaat gaagtatgat atatattact ccaatatgtc
    15961 gtaagataga aatgatatat ataggtaatg gtatgtaggg taggaagaac aaactgaata
    16021 ataagattaa aattggtaaa ttagatatta atgctgctcc taaatttttc caataatctt
    16081 taaaaaaact gtttgcgaag tctctatagg gataggattc ctcgtgtcgt acaattttta
    16141 ttagagttgc tattagggca ctttcacctg atccgatagc aataactgtt actactgacg
    16201 ctacatagag tagatttaac attataagat ttgaaacttt atcaataaat tttatctgca
    16261 tctttaactc ctgctgtttt tatacttata atatcacatc atttgagttt catcaacttt
    16321 gaatacatta agaaagaata taactatgag gaaaggaaaa aattattatg aataaatcca
    16381 aaaaatataa agaaagaatt cattatgaat acgataatct tactaaatca gagaaaaaat
    16441 tgctgactat attttagtta gagatagtga aatagtttat gaaacgtctt cagaaattgt
    16501 tagtaaagta aaagttggag agggaactct taatcgattt tgcaaaaaga ttggatactc
    16561 tggttttcag gaactaaaat taaaaatgac gaaagatata ttagagttag aatctcaaaa
    16621 aatgagtagt gacacattta ttgatgaaat aaaaaataat tatttatcta ttgtggaaag
    16681 tacaagaaaa ttaattgatg gtagacaaat agaattagct ataaaattaa taagagaagc
    16741 aaaccagatt ttaatgattg gtgtgggttc tagtggaaat gcggctagag aatttgagag
    16801 tagtttgtta agaattggaa taataagtaa gacggtaatt gatacccatt ttcaactcat
    16861 gcatactgcg ttattgaaag ataatgattt gataatagcg tttagtttat ctggttccac
    16921 aaaagaagtt gaggaaactt tattaaacgc aaaaagaaaa aatgttaaaa ttatttcaat
    16981 aacaaattat tcgtccagaa atatagcaaa attatctgac tgcgttcttt tgacatcaaa
    17041 aaaagaatct tatttagagg gtggtagttt aatggctaag gcttctcaac tattcataat
    17101 tgatgtaata tgcactagac tctctttaat aaattatgaa gatactatat gtaaaaaaga
    17161 agagattgct tctttgctgt caaataaagt ggaataaatc aataattttt aaattttaat
    17221 aaaaattttt taaaataaat taaaaaacga tcctaaaagg gtcgtttttt tgctaaagtt
    17281 ttaaaaataa acaataatta agattatagt gcgttgaatc tatattagga cataacaatt
    17341 cttaaatcat tgttagaaat tagtttgaat tttccaatca atttgttcga tttttacatc
    17401 attgcattat atcacgtgac tattaacctt gttttctcct aaaattgatt ttcttctttt
    17461 cttatcttgt ccactcgaaa caagtattgt aagaatttga ttatttttga aagtactttt
    17521 aatatatttg agatagttaa aaaagatttg aaactaaatt ccaaattaga aaaagacttg
    17581 aaatgctaaa aaaaaaaagt atactctaat tgaaaacggt aacaaaacta atttagagaa
    17641 tgaaatatag agtatttctc tcttaaaagt ttttggtgaa acgagatgta gaaaggagat
    17701 ttagccaaag agtctattag tgctagaata atagattaga attatagtgt attgaatcta
    17761 taacagtacg ccttaaatgc taaaatattt ctataaatta atttaacttt cctgataggg
    17821 ctgttcatat cttatttcaa ttcactatat aaataaaatt gtagtagatg ttattgaatt
    17881 agtaaaaaaa ataaaaaaac ggaggttttc tgaatggaaa ctaaaaaaat taaaaattta
    17941 aaaggtcaaa taattgtttc ctgccaagcg ttagaaggag agccacttta tactccaaat
    18001 ggaggagtga tgccgttatt agcaaaagcc gcctttcaag caggcgctaa aggtattcgt
    18061 gctaattctg tccgcgatat ttcagaaata aaagaagaag ttgacttacc aattataggt
    18121 atcataaaaa gagattacga tggctttgaa ccttttattt cagcaactat gaaagagatt
    18181 gatgaattag ttagtgaagg agtagacatt ttagctttgg attgtactaa tcgttcaaga
    18241 ccaggttatg ataatattac tgactttatt catgatatta aagtcaagta tccaaaccaa
    18301 ttattaatgg ctgctatttc tacttttgaa gaagggaaag tagctgctga atcgggagta
    18361 gattttgtgg gtacgacatt atctggttat acaccatata gccctaaaaa agataatcct
    18421 gattttgagt tagttgaaag attggtaaaa gagcttgacg taccagttat tgctgaagga
    18481 agaataagta ctccggaaca agctagaaaa atgttagatt taggtgctta cgcagtggtt
    18541 gttggaggag ctatcactcg tcctttggaa atagcgaaga agtttattga ggtagtttag
    18601 atgaatcaag aaatattaaa aaagagtaag attcaattga cagttgaaca tattcaaaaa
    18661 tattggattt tatatttaat gatgattcca gcaactgttc tactaatttt atttacgtat
    18721 ggaccaatgt acggcattat tatggccttt caagacttta ctgtcttcaa gggatatact
    18781 ggaagtccat ttgtcggttt aaaacatttt caaagattgt tctcagatcc tttgttttat
    18841 agattgttca agaatacgtt catggtaggg gttttagatt ttttattctt tttcccagct
    18901 ccgcttattt ttgcactcat attaaacgaa gtcagaaaag taagatttaa gagtgtagtt
    18961 caatctatta gttatcttcc tcattttatt cccctagtgg ttatggttgg tattattttt
    19021 gaactatttg gttcatatgg tattattaac agtttacttt catcacttgg aatggagcca
    19081 ataagtttct ttacaaaatc tgaatggttc ttgcctctct acattggttc aggagtatgg
    19141 aaaacaatag gttggggttc tatcatttat atgggagcat taaccaatat agattcaact
    19201 ttatatgaag cagcagatat ggacggggct aatagatggc acaaaatgtg gcatgtaact
    19261 ctaccaagtt taagacctac agtagttact ttgtttatac taaatgctgg tggtatcatg
    19321 caagtaggat ttgaaaaggt attcttgatg tctagtcctg caacatatga agtatctgat
    19381 gtattatcta cttatgttta tagacaaggt attttaaatt ctgatttcag ttactcagct
    19441 gcagtaggat tatttaataa catagtagct ttgttatttg ttttattagc taataagatt
    19501 gctaaaaaac ttggcgaaga aggaattgta taaggggggt aaaatgattt tttcaaaaaa
    19561 tacaaaaaag agtaatagag acaaagaaac cttcgttgat tatctcttta tattcatttt
    19621 aataataata accttactta tgttgtatcc attatggtgg gtagtgatga cgtcactttc
    19681 agaaccagtt tggctatcta aaaacgttgt taaattattt cccttaaaaa tagatattac
    19741 tgcatataag tttatttttg gggattctaa actatggcaa gcatatggta atagtgtatt
    19801 gtatgctgca ctatctacaa ttgttagtgt tgcggtatgt agtatgtatg cctatccact
    19861 tacaattcct gaaattaggg gtaaaaaatt ctggaatact cttattttga ttccaatgtt
    19921 ctttagtgga ggaatgatcc cgctttatat acaagttgca aacctcggtt tattgaatac
    19981 tgcttgggct cttgttttac ctggtgctgt ttctacatat tatataattt tgtttagaac
    20041 acagtttaaa tcaatcccaa tggagcttcg tgagtctgct agaattgatg gggcaagtga
    20101 atttagaatt ttttggaatt tagtattacc attatcaaaa gttattttca tgattatagc
    20161 actttattgc atagttggtt catggaatag ttttactcct ccattacttt atttgaatga
    20221 cgacactaag atgcctttat ctatttattt gagaaattta gtcgttacaa atacaactga
    20281 tactgctgaa ttatcacttt ctgcaggtaa tacatattac caacaaattg ctgctcaagg
    20341 tggaggtatt ggtatgcgta ttgctattaa gatgggtact attgttgtta gtgttattcc
    20401 aattatgatg atttatccat ttattcagaa acattttgtt aagggaatcc tgctaggttc
    20461 tgtgaaaggt taataaggta attattttgc aaaatttaaa aaaatatctt ttattagata
    20521 gcggtttagt agttgggtat acattagaaa atgctcaatt aaaattaaat aagctaaaaa
    20581 aagatactga aaacaatcca ctatttggtg aagagtattt tgccgaaaat cctaaattat
    20641 gggaagttcg ttttgataat tcatatccaa acgttatcta tgataaagaa ttgaaattat
    20701 atagatgttg gtatcaaaca tttgttagtg atgaagcaag cgaagagact cctttagcag
    20761 aacgtggaga gaaggaatac attgtcaagt catctagaat gacagcactt tgctatgctg
    20821 aaagtaaaga tggagtaaaa tgggaaaaac caaatctcaa tctagtaaaa tttaaaggtt
    20881 caaaagataa taatattgtt ctgatgcatg cacacggtgc aggtatcatg ctagatgaac
    20941 aggagttgga tcctaagaaa cgatataaat tagtttcaaa attagaattt tctccgaatc
    21001 ttcattacat ggttgttgtt ttttcagaag acggtattca ttttgacgaa cctattccat
    21061 ggaaaaaatg gaatcctgca gcagatagtc ataattttcc atttagagat ccaaaaactg
    21121 gtaaatacgc tgttattaca agaacctggg caaataacgt acgtctaagt gcaattactt
    21181 tcagtgatga ttttattaat tggtcagaac ctaaagaaat ccttagggga gatggatttg
    21241 aagatcaaat ttattctatg ccagtaattt catacgcgga tatctattta ggttttgctt
    21301 caatgtacca tgaaggcgac actttaaatg aaaactatga taaagtagac ttagaattga
    21361 aattctctgc taatttggaa caatgggata gtgtatgtaa gggcgactat ctcattgaaa
    21421 ggggaggtgg agtatacccg cagaatgctg attttgatgc tagttgtatt ttcacggctg
    21481 ctccaataat tgaagatgat aagatttggt tctactatat gggtggaaat ggtaatcaca
    21541 ctggcttccg agaaagttca ttagctagag gatatattaa gaaagaccaa tttgcttatt
    21601 atactaataa gagagaagga attccagcta aaatatctac agttagcttc caaacttacg
    21661 atgatgaaat ttatatctta gctgatattc ctgaaaatgg ttatattaaa gttgcggtag
    21721 gtactaaata cggtaatgct tattcagatt tcggtcagga agatatctct cttgttcaag
    21781 tttccgatgg taagtataag ttggaattta ataaaaaatc tatcttagat ttaggtaatt
    21841 ctccagttgc gttcaaattt gaaatcgaga atgcaaaatt gtatggtatt gaaggtagta
    21901 ttcagcaaca ctatctcaaa tattaaccag aataattcgt taacaaataa tctctatatt
    21961 agtggagata gatatataaa atggaggtct tattatggta aagcttaata aggtattaaa
    22021 agggagtgtt gcattcctga gtgcaagttt attgctagca gcttgtggca ataacgctaa
    22081 ttcaaagccc gctgaaaaaa cagctgatgg taaaacgaaa atttcgtttc tatctacatg
    22141 gcaaattaat gatgttcgtc cgcctaaaga tgaaacactt gttggtcaat ggttagaaga
    22201 acagctaggt attgatattg atcttgtaac tattcctggc gagggagtaa gttctaaagt
    22261 aaattctctt attactagta accagttacc gactgttttg ttgacaacag gagataagag
    22321 tgatatcgct ggtatcaaca aacttggtaa acagggtgca ttcttagatt tgtcacaaca
    22381 catggacaaa ctaccaaact ataagaagta ccttgaaaaa aataatgcat tagctcaaat
    22441 agaagatgat gaaaaacata tttatgcttt cacaaaattc tttactgatg agaatatcat
    22501 gtatactaca ccaattctga gaaaagactt acttgttggt tcagaatttg aagatctttc
    22561 aaaaattaaa actgttgatg actatacaaa agttttgaaa tatttgactg aaaaacaagg
    22621 ttctccagca tttattcaac gtaatggcta tgaaggcttc atgaagcgag ttacaccatt
    22681 gtggaattta agccatcgta catactatga ctatgaatca gattcatata aacatccagt
    22741 tgaacaacct caattgaaac aattcgttga atggttgaaa gaattacgta aagataacgt
    22801 acttcaccct gactgggcag ttatgaaaga tgaaacttgg gaaggtctat tggcttctaa
    22861 caagggttca ttcactgttg accgtatgaa tatcattgga gataataact ttgataaatc
    22921 atttgattgg cagccacttg tttatccaga aattaatgga aaacgttatt tgcaaccgaa
    22981 aacaccgtac atttctgatt caggttgggt aatcaatgcc aatgcaccaa aagaagaaat
    23041 tgataaagcg ttagaattct ttaatttctt atacgctgat gaaaatcaag aaaaacttgc
    23101 tattggattt gaaggtaaaa catttacacg tgaaaaccct aatactcaag caggtattaa
    23161 atggttgatt caaatttacg gtgaaaatgc tggaaatgat aaagcagaac tgctgtttaa
    23221 acatggtaac caagcattta ctcgcgttca aactaaatta gatattgagg cacagccagg
    23281 aacattccct aaagttatgt atgatcaagt agataaaatt aagaaagatt taggtggttt
    23341 tagaccagat actccggttc tttcctttac aactgaagaa ttagatgttt taactaaatc
    23401 tgaagcagga ttaaatactt tctttgatga aaatattatt aaattcattg aaggacaaag
    23461 agatatgagt gagtgggatt catttatcaa tgaagctaaa tctaaagact tggataaagt
    23521 tacaaaagta tataatgatg cctacaaacg tgtcaaagat agaatgaaat agactaaatg
    23581 gtagctctct ggtttttcag agagctacta ctgcctgagg gggagtaagc tttgtatgat
    23641 gtagtaatta taggtgcagg aagttcgggc gcattggctg caattgcttc ggggcgtcta
    23701 gggttaaaaa cttgtctaat agagaaggga agtagaattg gtggagttcc tattaataca
    23761 ctaatggggt catttgctaa tctatatttt gatgattctg gtagagtaaa tgcaagtaaa
    23821 attgttgggg aattaataga acgtattatc aaaaaaggtg gtactgtctt taactctatg
    23881 gaagaattga tgaatgtaaa tgatttttat cagattacaa ttccctatca accagaagtt
    23941 tatgaatcgg ttttaactga tatgttgatt gagtctaaag ttgatatttt actaaatgtt
    24001 gaagttaata atattattta tgatagtaaa aatattaaaa gtcttgaaat tttaagtaat
    24061 caggaagtta aattgattga ttctaaagtt tttattgatg ctacagggaa tgcaacaatt
    24121 gcttctgcta gtggagctga tgtttatgaa aaaaattctt cttacggttg tttaatgaga
    24181 gttggaggag ttgatatctc aaagactata gaacatattg aaaaaacaaa gcagtggaac
    24241 tatatagaag gatataatca gtggttagaa gaagtattag caaatcgaaa gtacagagcc
    24301 actggagcag ttttaaaaga tccagtttct tatgatcatg cccctatgct ttcaaaagac
    24361 gaccatttta tgaatgatga aaaatggaat tacattaaag aaagatggga aaaatttaga
    24421 tttatttaca ctttagaagt atcactattt aggaatgaat taaaaaaagc tgtagaatct
    24481 ggggatttta attttgaaat ttatcatgat gataaatctg gagtcactat gaatggcgac
    24541 ggtataagct atggttcatg gggtcaaaat gtagcattaa ttaatgttgc aaaagcattt
    24601 ggattcaatc ccaaatatat ggaagatgaa tcacatgcta atattctttc tagaaaatat
    24661 aatttaacat ttttatcttt tcttaaaaaa tatgtaccag gttttgaaaa ttcttttatc
    24721 cttgatcagg gaactagagc tactaacaga tcatgtaggc acattgataa ttcatctatg
    24781 atggacgaaa ttcttgattt tccaatgtat acatttaaga ctatgtatag ctatcaaact
    24841 cctaaagaaa taacgtacaa atcaattgta ggtggaaaat tgaataattt gtttgtaata
    24901 ggtaaaggtg cttaccaatc cgaaagtttt agatcacaaa ttagttgtat gttaatgggg
    24961 atatcatcag cagcagcggc aaaaactatt attgaagata aaagcaatac tctaaacatt
    25021 aatagagatt tgtttaaatc gaacttagat atattattta catgggagtt ttctaattgg
    25081 attactgatt aacaaataat aagggaatat taaatgaatg atactaataa aaatcaatac
    25141 tttgtttatg aatttgatac tagctttgta gaaatgtctt attctcagtt ttttgaagga
    25201 tattgtattc ttttttcaaa agaaccctat ccttctttat ctgatatgcc aatggaattt
    25261 agaaaagaat ttttaatgga aatgagtata ttaggtgatg cgatgcttga agtgttaaat
    25321 gcctatagaa ttaattatga tatcttagga aattcaacac ctgtacttca tgctcattta
    25381 tttccgagat acatgtggga agaggaagag agaagaaaaa ctgtagttca tagatatgat
    25441 tcttcagttt ttagcaatcc tgagtttgaa tttactatag aaaagcatgg accaattatt
    25501 aaaaaactga ggtctgctat tgatagacat tatagagagt atcaacaatt attagatgat
    25561 tcaaactgaa ctccacattt tcgattagat ttaatacctt gtatattaca actaggttgt
    25621 ggatgatata attttttgaa aaatatattt taggaatgac ttataaagca attatatcag
    25681 aggctattaa atcaatggcc aaagcttatg ctccttattc tgattttaag gttggagctg
    25741 cgttagtaac tgaagataaa aaattttttc tggatgtaat atagaaaatg ctgctttttc
    25801 tcctacttgc tgtgcagaac gagtatcttt ttataaagct gtatttaaag gagaacgttc
    25861 gttttcaaga acatgtattg taggtggaaa aaatggtatc ttatcatctt ttatagcacc
    25921 ttgcggagtg tgtcgccagg taatgataga atttgtaatc ctgattcatt tgaagttata
    25981 ttggctagtg atgttgatac ttataaagta tataaactta aagaactact accagttagt
    26041 tttaatcaag aaaatttata acaggaggga actatggaat tagttgaatt taaaaatgga
    26101 catgttaata cggttcatga gcatatcgca ataacgaaag taaaagagtt tctaaataat
    26161 catgatatat taaaagataa aggtggcata cataaaattt ctactgattt cttttacaat
    26221 ataattgata tggaaactac aactgaagag aatagaccgt gggaaagtca taaggaatat
    26281 tatgatgtcc attatctgtt aaatggagaa gaaacaattt tatataactt cttgtctcaa
    26341 atggaattgt ctgaatataa agtagatgat gattggcaac aaatgaatgg gacagcttta
    26401 tttagtatta aattaaagaa agatatgtta cttttgttgg aaccaaacga tgcacataga
    26461 acaggcctat tggttgaaga accacttaat attaagaaag ttgtttttaa ggtaaaaatt
    26521 taactgaaag tactttcggg gattaagaat tttaaaatat ttaagaaatt gtattctaaa
    26581 gttctaaaat tatagatatt taatttaaag cttgttaaaa tagaatagta acactcatct
    26641 gctttcaaaa agcattctat tccatctccg attaacgatg gactttatca cctccttctc
    26701 cagtccttgt atgacatctt ggagttgatt catgacatct tccaaagttc gaaaggcttt
    26761 attcttaaat ccacgtttat gaatctcttt ccacacttgt tcgatgggtt catctctggt
    26821 gtgtatggag gaataaatgc aaaaccaata ttagtcggag tctttaaggt acttgattta
    26881 tgccatatag cattgtccat aacgagtaaa agataatcat ctggataagc ttgtgaaagc
    26941 tcttctaaaa aggcgttcat ccactcagta ttacatccac cagctattaa gaaaaatgat
    27001 tcgcctgtat gggcatcaac agctccataa caatagtgaa attctcgtat atagtgacta
    27061 tggacatgtg gacctactcc tattggagac caacaagatc ccagtttact gattctaccg
    27121 aagccagcct catcttggta catcaagcga accttatgaa aacgtctact ggttttaaag
    27181 cgctttcttt tcttcagttg atttcatatc actattgtat aatgcttttt gattttagtc
    27241 tagtataaat agcgagaaat atctatccta tcttctagaa tgtcttccaa acgaggaaac
    27301 tctcgtaaac aaagaggttt tagaggccta tttaccgtgg actaaagttg cacaagaaaa
    27361 gtgcaaataa gaaatctcca gattaggaac tatccgtgag ttctctagtc tggagatttt
    27421 tcaatagact tcctgcgaaa caaaatatgg tataatagtt ctatgaatta tgaagcaagt
    27481 aaacaactaa c
//
LOCUS       DAVBEM010000029        27275 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVBEM010000029 DAVBEM010000000
VERSION     DAVBEM010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27275
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.029"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            228..1910
                     /locus_tag="VQ548_001246"
     CDS             228..1910
                     /locus_tag="VQ548_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2654096.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELVKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHRKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            1895..2725
                     /locus_tag="VQ548_001247"
     CDS             1895..2725
                     /locus_tag="VQ548_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2654097.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVASLLLSLQNQGRFYNPWK
                     "
     gene            2918..3421
                     /locus_tag="VQ548_001248"
     CDS             2918..3421
                     /locus_tag="VQ548_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HET2654098.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      3475..3709
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            3874..4437
                     /locus_tag="VQ548_001249"
     CDS             3874..4437
                     /locus_tag="VQ548_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2654099.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTVAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYILLKPTLKHYER"
     gene            4451..5077
                     /locus_tag="VQ548_001250"
     CDS             4451..5077
                     /locus_tag="VQ548_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET2654100.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRSLTRLIDIPVIITWVVIIAFVFYRKRWKIESFFMLGNLTLAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGALFIEFPFYDKLRFQWRFKGKQK"
     gene            5189..6061
                     /locus_tag="VQ548_001251"
     CDS             5189..6061
                     /locus_tag="VQ548_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000525616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2654101.1"
                     /translation="MGMLLATRLKNKRKELKLSQKELAEGICEQGQISRMEQGKYSPG
                     SELLFQLSKRLKVSMDYFFEDTEVSSLENIDKFKELSKKFLDEREYESLHYIYELEKS
                     KRARLSAKDQIYLDWIDTLVQFCYLNHQTGAVAKLEKILLSLKKSDFYYLQLGNTLAN
                     FYFDMGQEDTYQELYQLLKENLQSLSVHHLEQLELMIKFRYNYCRYLWLNERTSEAIE
                     EITETIAICKRYNSSYRLADLYCLLGSISEGFAERDRILGFYQVSYQLYKHEENQRMM
                     LEIEKEMKLLESED"
     gene            6191..6328
                     /locus_tag="VQ548_001252"
     CDS             6191..6328
                     /locus_tag="VQ548_001252"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654102.1"
                     /translation="MKRSQVVKRCILIALLLLFLLNVLSGSLSVTTRGVDPRPAYGVS
                     L"
     gene            6752..7666
                     /locus_tag="VQ548_001253"
     CDS             6752..7666
                     /locus_tag="VQ548_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HET2654103.1"
                     /translation="MKLYQINDGIQIFESSNLEKIVIRNYRNGKKITIDHQPLLKKLL
                     LFLEVPKREEEILLYLPELSNKTLRSVLTNFMSLNIIHCQDTLIIHKKINILIIGLGT
                     TGGYLADGLCRSNINSKLFLLDKDRVDETNVGRQIYLRDDIGQYKVDVFKQKFSDKEI
                     KVFKIFINSKKDLEKICKREGIDLVIQCGDSPSPRELGKIVNTVCDTLQIPYIVNTGY
                     MSNVVPLPEFYYPNNRYNFNYKHQFSDEKLLFSQVLSKADYMVAIQSSFVMLMQIKNF
                     IFNEEPIYYGYRGYYNSVTLAWEVEKID"
     gene            7659..8672
                     /locus_tag="VQ548_001254"
     CDS             7659..8672
                     /locus_tag="VQ548_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654104.1"
                     /translation="MTKYLELDYSHSYILEGFRKNDAFIENHKECLDMLSDKIWRDNK
                     YMNTEKNISSPTRTILSRYTCNILSSLFIDISKNSIEKLIVTCENSDLNWIYNYYKSV
                     YNGVFCELRQLIQQYCKVKDKYEKWLFIKAIINQGIRQNEKEVVEFFLKQLKDNNQGI
                     FDYINSFSFYLLKFYSKDKSRIFLEEQLDIDDFLGSDKEDYARSLVFKNYASLLPDTS
                     ELKRNIMEKCLSQTPQDTDLWKEWFETYASQKEIRQKATEIFKHGYSDISLLKLVKIE
                     PDDTESLIRMIILCTSDLNSNIARYLISFLSDGRLKEFLELFVENFDFLNIIEGKTSE
                     INF"
     gene            8656..10248
                     /locus_tag="VQ548_001255"
     CDS             8656..10248
                     /locus_tag="VQ548_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001236730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2654105.1"
                     /translation="MRLIFRIIRKDIILYSILTFLLSIAMVSEAFLMQFIVDSIKFGE
                     KKYVLISIFIVIFLILQTLLYYYQQFLTAVLSKKSAYEYRKLIFKNIQQTSLRLVTGE
                     KNDSILASLTTQIDQIEYNYFYSVYWGGYLLCQLVVAIVMSLYLNPLMSVLTICLSLP
                     NLFVALLFKNSLEQKQEELINETNSSIAVTQDLIEGITDWKIANREPNIFRVFESKTL
                     KLLEKQVKVEKFQYIVVSLNQLFSNVLYFGSWIVGGFLIIRGQLSLGSLIAFSQLLAR
                     ISYPVYASSDLLSKYISGKKIVEILSKEFIFSDESRNYPDEFNVISFEHYFTNIDEKD
                     MPFDKEFYKNKKYLLKGKSGSGKTTILKSILREYDDYSGIVKINGVDVRDIKESVLFD
                     NIAYVSQKPHLFSASLRDNLTLFSEDFTDNEIVEVLKFVELSKWANKDCLDMMLSNDD
                     IKLSGGEVKRVSLARALLMNKNILLLDEFSAGIDYETLLKIEKKLIDLDKMIIYVTHV
                     DIDRSGKQFDDVIDLDCLFISS"
     gene            10440..11343
                     /locus_tag="VQ548_001256"
                     /pseudo
     CDS             10440..11343
                     /locus_tag="VQ548_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091364.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            11361..11498
                     /locus_tag="VQ548_001257"
                     /pseudo
     CDS             11361..11498
                     /locus_tag="VQ548_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
     gene            11526..11867
                     /locus_tag="VQ548_001258"
     CDS             11526..11867
                     /locus_tag="VQ548_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654106.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLKNHI
                     LPLWIGMVSFF"
     gene            11840..12151
                     /locus_tag="VQ548_001259"
                     /pseudo
     CDS             11840..12151
                     /locus_tag="VQ548_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            12279..12866
                     /locus_tag="VQ548_001260"
     CDS             12279..12866
                     /locus_tag="VQ548_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HET2654107.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            13256..14863
                     /locus_tag="VQ548_001261"
     CDS             13256..14863
                     /locus_tag="VQ548_001261"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HET2654108.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(15422..17053)
                     /locus_tag="VQ548_001262"
     CDS             complement(15422..17053)
                     /locus_tag="VQ548_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HET2654109.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGITITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            17346..22325
                     /locus_tag="VQ548_001263"
     CDS             17346..22325
                     /locus_tag="VQ548_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HET2654110.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETASPASNEAATTE
                     TAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEK
                     EVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNE
                     KASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDA
                     GHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFI
                     NQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYN
                     YQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKT
                     KVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGD
                     KDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR
                     WWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVA
                     HKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFF
                     EHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADF
                     YEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTT
                     FDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSA
                     QLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEV
                     RGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMA
                     KAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQ
                     SGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLR
                     VQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEAS
                     PKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQK
                     TGRQTLTLRYQGHEVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEA
                     FLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQ
                     ELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVF
                     SDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVD
                     LSYASIVKIPIEKDKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESA
                     EKPQPAKPAPQNKVLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRV
                     IIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQ
                     NTAVKSEEASKQLPNTGTADANEALIAVLASLGLASLALTLRRKREDKD"
     gene            22415..23611
                     /locus_tag="VQ548_001264"
     CDS             22415..23611
                     /locus_tag="VQ548_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HET2654111.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            23747..24274
                     /locus_tag="VQ548_001265"
     CDS             23747..24274
                     /locus_tag="VQ548_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET2654112.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            24351..24707
                     /gene="glnR"
                     /locus_tag="VQ548_001266"
     CDS             24351..24707
                     /gene="glnR"
                     /locus_tag="VQ548_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HET2654113.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            24744..26090
                     /gene="glnA"
                     /locus_tag="VQ548_001267"
     CDS             24744..26090
                     /gene="glnA"
                     /locus_tag="VQ548_001267"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HET2654114.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(26186..26305)
                     /locus_tag="VQ548_001268"
     CDS             complement(26186..26305)
                     /locus_tag="VQ548_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HET2654115.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            26793..27275
                     /locus_tag="VQ548_001269"
                     /pseudo
     CDS             26793..27275
                     /locus_tag="VQ548_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         8594 a         4569 c         5792 g         8320 t
ORIGIN      
        1 aaccatacct acggcaaggc gaaactgacg tggtttgaag agattttcga agagtataaa
       61 atgatgggga aggctgggca actagtcttt ttcgatgttt atagattagt taggcaagta
      121 agctaggata ggaatctttt tggtgctaag attttaagag aagagactgc aagaagggct
      181 tgatttatga taaaatagaa gtctaagaag cgaatgaaga gagtaagatg aaagaagcta
      241 taattgagtg gaaggatttc tctttccggt atgaaacaca acaagaaccg accttgcaag
      301 ggatagactt gaccatttac aagggagaga aagtcttaat tgttggacca tctggatcag
      361 gtaaatctac cttgggtcag tgtttgaatg ggattattcc caatatttac aagggtcaga
      421 catatggaga atttttgata aagggtcaaa cagcctttga tatgagcatc tatgataagt
      481 ctcatctggt tagcacagtt ttgcaggata cagatgggca gtttattggc ttgtctgtgg
      541 cagaagattt ggcgtttgct ctggaaaatg atgtgacagc cctagatgag atgaaaggtc
      601 gtgtttataa atgggctgaa aagctggacc ttcttccttt actggatcag cgtcctcagg
      661 atttgtcagg tggacaaaag cagcgagtca gtctggctgg tgtcttgatt gatgaaagtc
      721 cgattctctt gtttgatgag ccactcgcca atctagatcc caagtcaggt caggatatta
      781 tcgaattgat tgaccagatt cataaggaag aggggacgac gactcttatt atcgagcacc
      841 gtttggagga tgttctgcat cgccctgtgg atcggattgt cttgataaac gatggtcgta
      901 tcctttttaa tgggagccct gaccagttgc ttgcgactga tttattgact caaaatggaa
      961 ttcgagaacc cctttatcta accactctcc gtcaattagg tgtggactta gtcaaggaag
     1021 aacagttagc gaatctggat aacatgtcta tctcaaaagg tcaggttcag ctgcagaatg
     1081 aactggtaaa agaaactcca gaattgcagt cactctttaa attagaggac gtgtctttct
     1141 cttatgatga tagaccgatt ttaaaatccc tacatttaga tattaaaaag ggtgaaaaga
     1201 ttgctattgt cggaaaaaat ggagcaggga aatcaactct agccaaggct ataagtagct
     1261 ttattcagac ggaaggacgc tatctttggg aaaaacagga tataaaaggc gattctgttg
     1321 cagagcgggc ggaacgagta ggctatgtgc tacaaaatcc taatcaaatg atttcaacca
     1381 atatgatttt tgatgaggtg gctctagggc tccgtttgcg aggtgtggat gagaaggaaa
     1441 ttgaaacgag agtctatgaa accttgaaaa tctgtggact ttatgaattc cgtaattggc
     1501 ctatttctgc cctgtcattt ggtcagaaaa aacgtgtcac cattgcttca attttggtct
     1561 taggagctga aattattctc ctagatgaac cgactgcagg tcaagatcag aagaactata
     1621 ctgagattat ggaatttctc gaagagttac atcgaaaagg gcataccatt gtcatgatta
     1681 cccatgatat gcaattgatg ctggattatt cagaccgagt ccttgtcatg gtggatggag
     1741 aattgattgc cgatactgtt ccagccagtc tgttgagcga tcctgagctg ttagtaaaag
     1801 ccaatctaaa agaaacctcc atctttaact tggctaagaa actagatgtg gatccactgg
     1861 atttaacggc attttacaaa gaaaggagag agggatgcaa gctaaattaa tcggttacca
     1921 gcatagagat actgtgattc atcgcttgtc aggagctggg aaacttctct ttttcattct
     1981 ggtatcattg gcggccatga ttagctatga taccagaatg ctcttgctga ttgccatctt
     2041 ttcagtcttt ctcctctatt tatcagaaat tcgctttaaa gatgtttcct ttgtagccgt
     2101 ttttgcgacg gtatttgccg ttttaaacgt tttgatggtc tatctctttt ctcccgagta
     2161 tggggttgga ctttatggag agagaagtgt gatttggcag ggaatcggtg tctacactct
     2221 aaccagccag gagctctttt atctgctaaa tttggccatt aagtatcttt gcaccattcc
     2281 tctggctatt atctttttga tgacaaccca tcctagtcag tttgcttcca gtttaaatca
     2341 aattggtgtg ccctataaga ttgcttattc tgtcagcctg accttgcgct atattccaga
     2401 tttgcaggaa gaattcttta ctatcaagat gtctcaggag gcgcgtggga tggaattatc
     2461 caagaaagct tctcttatgc aacgaatcaa aggcaatctg ctcattatta cgcccttgat
     2521 ttttagctcg ctagaacgca ttgataccat tgcgactgcc atggagcttc gccgctttgg
     2581 gaaagaaaaa aaacgcacat ggtatagtta tcaggccttg aaaaaaggag actatattac
     2641 cttgctcttg gcaaccttgt ttttagtagc tagtttacta cttagcttgc agaatcaggg
     2701 acgattttac aacccttgga aatagcttga aaaaattgaa aaaatcaagt cgtttctatt
     2761 gacaatgatt ctgaaagtgt tatactaaga aagtagtttc gctgatttac ttcaaacctg
     2821 ttgtgaggta agttaacgat gccttaacca cgctgtttgc tgagcttgac tccgggcagt
     2881 gtggctattt ttttgcaatg gtgaaaggaa gcaagtcatg acaaatcaca ttgtattatt
     2941 tgaacctcaa attccacaaa atacgggcaa tatcgcgcgt acttgcgctg cgaccaattc
     3001 tcccctccac atcatcaagc ctatgggctt tcctattgat gaccgcaaga tgaagcgggc
     3061 tggattggat tactgggata agctagagat ttatttttac gagagtttgg aagatttcat
     3121 atctcagatg aagggaaaac tctatctgat ttcgaaattc gcggaaaaag tctattctga
     3181 ggtggattta tcgactgacg aggaccatta ttttctcttt ggacgtgaag acaagggctt
     3241 acctgaagat tttatgcgag aacatcctga gaaggctctc cgtattccca tgaatgatga
     3301 acatgtccgc agtctcaatg tgtctaatac cgtctgcatg attgtctatg aggctcttcg
     3361 ccagcagaac tttgcaggtc ttgaactcgt ccatacctat gaagtggata aattgaaata
     3421 aaaaatgaaa atgaacaaaa tgcttgcgct tgcaagcgtt ttttgttatg ataaaagagt
     3481 cttcagggca gggtgtgatt cccgaccggc ggtgacttta actaggaaat gatcttttcc
     3541 ttttatactt tgttgacaag ctttgcctaa ccagaagtta tgcctacagc ttgtcgccta
     3601 gtctaaaaga aaaatctcta tttccttctc tttaaagaag tccgcgagcg caagctgatg
     3661 tggtgagatt ccacaaccga cagtatagtc tggatgggag aagacgaaag aatagctttg
     3721 tctgttttga tagatttata gccggattgt aaccacttgc tttgtttttc tttaatagag
     3781 taggagggaa cttttgggat ataaaaagtg agaatagata gaggaatcct ttccaacttc
     3841 ttctgatttt atagaaaatt ggaggaacct gttatgacaa acacacgtcg actttcgacc
     3901 attgcaattt tatcagccat ctcatttgtg ctgatgtact ttgactttcc gcttttacca
     3961 gcggcatctt tcctcaagat cgaatttagt atcttgccag tccttgtggg tctggtggtc
     4021 atggatttgc ctgctgctct aggagtgctc ttgcttcgct cactcttgaa attgcttctt
     4081 aacagccaag gagtgaatac ttacattggt ttgccgatga atatcgtagc tttgggagtt
     4141 tttgtcatcg tatttgcttt gatttggaaa aaggaacgga caacccttcg tttcctacta
     4201 ggctctctag ctgggactat tggtttaacc gtggctatgt tagttctcaa ctatgtttat
     4261 gctgttcctt tgtacgctaa gtttgctaac tttgatattg gaaaaatttt gggactttcc
     4321 aactacctaa tgaccatggt attacctttt aacttgattg aaggtgtaat cttttccgtt
     4381 tcattctggt tgttgtacat tctcttgaaa ccaaccttaa aacattatga aagataaaca
     4441 aacattttta atgaagggca gttttgccct tttacttttc gttattcttg gctatatggt
     4501 caaattttac cctgaaatgt tggtcaattt tgaccaatcg attcagactg ccattcgagg
     4561 agacttacca gattatttga ctattctttt tcgatccctc acacgtctga ttgatattcc
     4621 agtgattatc acttgggttg tcattatagc ttttgtcttt tatcgtaagc gatggaagat
     4681 agaaagtttc ttcatgctgg gaaatctgac tttggcaggt cttttaatcg tgacctttaa
     4741 aaatatctac cagcgcccac gaccagctat cttacatctg gtggaggaga agggattttc
     4801 cttcccaagt gggcattctc tggctgtaac gctgatggta gggactttga ttgttattct
     4861 tagtcagcgg attaaagatc aggtctggag aaaaatcgta caaatcgtcc ttggcctcta
     4921 cctagtcagt gtgctggtat caagagtcta tctgggagtt cattacccat cagatgttct
     4981 tgccagtctc tgtgtgggct tgggagccct gtttatcgag tttccctttt atgataagct
     5041 ccgcttccaa tggcgattta aaggcaaaca gaaatgatgg aaaagataaa aaattgtaca
     5101 aatacaaata gaaccatatg aaatatatac ttgaaacatg ttttggagtt tgatatattt
     5161 taataaataa agcaaggagg aagaaagtgt gggtatgtta ttagcgacac gcttaaaaaa
     5221 taaaagaaag gaattaaaat tatctcaaaa agaattagct gaggggattt gtgagcaagg
     5281 gcagattagc cgtatggagc aaggtaaata ctcacctggg tcagaattac tctttcaact
     5341 atctaagcga ttgaaggtga gcatggatta tttctttgaa gatactgagg tttctagttt
     5401 agaaaatatt gataagttta aagaattatc taagaaattt ttggatgaga gggaatatga
     5461 atctctccat tacatctatg aactggaaaa atctaaacgt gctcgtctat ctgctaaaga
     5521 ccagatttat ttggattgga ttgatacatt agttcaattc tgttatttaa atcatcaaac
     5581 aggggcagtt gcgaaactgg aaaaaatact gttatctctg aaaaaatctg atttttacta
     5641 tctacaactg ggaaatacct tggctaattt ttattttgat atggggcagg aagacacata
     5701 tcaggaactc tatcaacttt taaaagagaa cctccagtca ctatctgttc atcatttgga
     5761 acagttagaa ttgatgatta aattccgata taactattgt agatatttgt ggttgaatga
     5821 acgaacatct gaagctatag aagaaattac agaaacgata gctatttgta aaagatataa
     5881 tagtagttat cgattagcag atttgtattg tttattggga agtataagcg agggctttgc
     5941 tgaaagggat aggatactag gtttttatca agtatcttac cagctttaca agcacgaaga
     6001 gaaccagaga atgatgctag aaattgagaa ggaaatgaaa ttattggaaa gtgaagatta
     6061 agcaaaaaga tttgtattct tagataactt taatacatat tataaaaaaa ataaaaaaat
     6121 atcataaaaa ttattgacaa accaaaattg atgtgttaga atatcaccaa tagttaagga
     6181 ggtttagaag atgaaaagat ctcaagttgt caaacgatgt atattaattg ctttattgct
     6241 tctatttcta cttaatgtgt taagtggttc tttatctgta acaactagag gagttgatcc
     6301 aagaccagca tatggagttt cgctttaaag ttgtgcatag ttcttctttt atagacggag
     6361 agtttttctc aatagtaagt gattcaaatt ttgatggatg attttccatt aaattaagtg
     6421 attgcgaaaa ctttttgaaa tacattctct ttggatattg aaagtttgtt ttggattttt
     6481 ttatgaagct tatcttagct gttagattgg ggttttatgg gatttgtcct caccgggaaa
     6541 aaatcttaaa tctttgaaga aagaggtttt tatcttatgg ttagagatac atcagaagaa
     6601 attgaagtta ttgacttgtc ttctatgacc gtttcctact catctgttat gctaggaaac
     6661 tcttggatga cgtggaattg atttattaag atagattatt tggtttttac caaaaatctg
     6721 tctttttaat ttttaaagga ctaatggtga tatgaaacta tatcaaataa atgatgggat
     6781 acaaattttt gaaagtagta atcttgaaaa aatagtaatt agaaattata ggaatggtaa
     6841 gaaaataact atcgatcacc aaccattatt aaaaaaatta ctactattcc ttgaagttcc
     6901 taaacgtgaa gaagaaattc tattatatct tccagaatta tcaaataaaa cattacgaag
     6961 tgttttgacg aattttatga gtttaaatat aattcattgt caagatacat taataattca
     7021 caaaaaaata aacatattga taataggttt agggactacg ggtggatatc tggcagatgg
     7081 gttatgtcgt agtaatatta attcgaagct atttctttta gataaggatc gtgtagatga
     7141 gactaatgta ggtagacaga tttatttaag agatgatatt ggtcaatata aagttgatgt
     7201 atttaaacaa aagtttagtg ataaagaaat aaaggtattc aaaattttta ttaatagtaa
     7261 gaaagatttg gaaaagattt gcaaaaggga gggtatcgat ttggttatac aatgtggtga
     7321 ctccccttca cctcgagaat taggaaaaat tgtgaataca gtatgtgata ctctccagat
     7381 accttatata gttaacactg gctacatgag taatgtagtt cctttgccag aattttatta
     7441 tccaaataat agatacaatt ttaattataa gcatcaattt tcagatgaaa agttactgtt
     7501 ctcacaagtt ttgtctaaag ctgattatat ggtggcaatt caatcatcat ttgtaatgtt
     7561 aatgcaaata aaaaatttta tatttaatga agaacctatt tattatggtt ataggggata
     7621 ctataattct gtaacattag catgggaggt ggaaaaaatt gactaaatat ttagaattgg
     7681 attattctca ttcatatatt ttggaaggtt ttagaaaaaa tgatgcgttt attgaaaatc
     7741 acaaagaatg ccttgatatg ttatcagata agatttggcg agataataaa tatatgaata
     7801 cagaaaaaaa catatcatca ccgacacgaa caatcttatc acgctatact tgtaatattt
     7861 tatcgtcttt gtttattgat attagcaaaa atagcataga aaaattgata gtgacatgtg
     7921 aaaatagcga tcttaattgg atttataatt attataaatc ggtttacaat ggagtatttt
     7981 gtgaattgcg acaacttata caacagtact gtaaggtgaa ggataagtat gaaaagtggc
     8041 tttttataaa agctattata aatcaaggta ttcgtcaaaa tgagaaagaa gttgttgaat
     8101 tctttttaaa acaattgaag gataataatc aaggtatttt tgattacatc aatagtttta
     8161 gtttttatct attaaagttt tattcaaaag acaaatctcg cattttttta gaagagcagc
     8221 tagatataga tgattttttg ggatcagata aagaagatta tgctaggtct ttagttttta
     8281 agaattatgc ttctctattg cctgatactt ctgaattaaa aagaaatatt atggaaaaat
     8341 gtttaagtca aacacctcaa gatacagatt tatggaaaga atggtttgaa acttatgcca
     8401 gtcagaaaga gattagacaa aaagcaacgg aaatatttaa gcatggttat tcagatattt
     8461 cgttactaaa attagttaaa attgagcctg atgacactga gagtttaatc agaatgatta
     8521 tcttatgtac cagtgaccta aatagtaata ttgcaaggta tttgatttca tttttgagcg
     8581 atgggcgatt aaaagaattt ttggagttat ttgttgaaaa ttttgacttt ttgaatatta
     8641 ttgagggaaa aactagtgag attaattttt agaataatta gaaaagatat tatattatat
     8701 tctatattaa catttttgct atcaatagcg atggtaagcg aagcattttt gatgcaattt
     8761 attgttgatt caattaaatt tggtgaaaag aagtatgttt tgatttctat ttttattgta
     8821 atttttttga ttcttcagac tttattgtat tactatcaac aatttcttac agctgtatta
     8881 agtaaaaaat ctgcatatga gtaccgtaaa ttaattttta aaaatattca gcagacttct
     8941 cttaggcttg ttacaggtga aaaaaatgat agtattctag cttctttgac aacgcaaatc
     9001 gatcaaatag aatataatta tttttattct gtttattggg gtggatattt gctttgccaa
     9061 ttagtggtag ctatagttat gtcgctttat ctaaatccat tgatgtctgt attaaccatt
     9121 tgcttaagtc tccctaattt atttgtagca cttcttttta aaaactcctt ggaacaaaag
     9181 caagaagagc taattaatga gacaaattcc tcaatagcag ttactcaaga tttaattgag
     9241 ggaattactg attggaaaat tgcaaataga gaacctaata tatttagagt gtttgaaagc
     9301 aaaacattga agcttttaga gaagcaagtg aaggtagaaa aatttcaata cattgttgtt
     9361 agtttaaatc aattgttttc aaatgtttta tattttggta gttggatagt aggtggattc
     9421 ttgattatac gggggcaact ttcattaggg agtttgatag cgttctctca attattagca
     9481 agaatttctt accctgttta cgcttcttcg gatttattgt caaaatatat tagcggtaaa
     9541 aaaattgtag aaattctttc taaagaattt atattttcag acgaaagcag aaattatcca
     9601 gatgagttta atgttatttc atttgaacat tattttacaa acattgacga aaaggatatg
     9661 ccttttgata aagaatttta caaaaataaa aaatatttgt tgaaagggaa aagtggtagt
     9721 gggaaaacaa caattttaaa atcgatttta cgagagtatg atgattatag tggaattgta
     9781 aaaattaatg gggtagatgt tagggatata aaagagagtg ttctttttga caatatagct
     9841 tatgtttccc aaaaacctca cttgttcagc gcaagtctta gagacaacct gacattattt
     9901 tctgaagact tcactgataa tgagatagtt gaggttttaa aatttgttga attatctaaa
     9961 tgggctaata aagattgctt ggatatgatg ctttcaaatg atgatataaa attatcagga
    10021 ggggaggtca aaagggtttc tttagctcga gccttattga tgaataagaa tattctgtta
    10081 ttggatgagt tctctgctgg gattgattat gaaacattgt taaaaataga gaagaaactc
    10141 attgatttgg ataagatgat tatttacgtg acgcatgtgg atatagatag atccggcaaa
    10201 cagtttgatg atgtcattga tttggattgt ctttttatat cctcgtgaca tgagagttga
    10261 gtcagttgaa ttattttgtc actctgttta gttcttgttg gtagtgtcag gtaatctttg
    10321 ttaatttttc aggaagtcta ttgaaatatc ctcttggtta tatattacga ggagtaatta
    10381 atggatattc tcgagaattc aatacaacaa tttgattcta aagttaagta tgtttcttta
    10441 tttgcggaat caatctttta tcagatacca tgagctattt tgcaggtgct atgatttctc
    10501 ctttgtatgt gaggattatc ggagatgata tgacagatgc tatgggggtt agacaggcaa
    10561 ctgctggtgt agttaatatt ctcagcaacc ttataggggg agttttgatt gggggtcatc
    10621 agtcttcaga tgtttgtagg tttgaatgct ttgacctttc tttttgcact gttgggtgtg
    10681 gtgtttattc gtacttcttt gagagatatt gaggaacaga tggaggttag taaaagatta
    10741 gccgcaaaat cttttggaga gcatttcctc cattcaatga agatattgtc aagttttcca
    10801 gccatcatca aattaatatt cattgcagct atgaaccaag tgattttaag cattattatc
    10861 cctttaacga ctttgatgtt aatccatcat ccatttatct tctttgacac tgggaaatcc
    10921 attgcagcat tgtcagtggt tattttttca ggaacgattg tgggaagttt tttgagtgga
    10981 ggtatcctaa aaaatattcc cataaaaatg attgtctact ttgaagaaat tatgcatctc
    11041 tgtattctct tttcttggtt gaccaatcat ttcctccttt tattggtagt tgtcttctta
    11101 tgcgcagttg cagtaggaat gatggggcct cggattttca accttgtatt ctcgatggtt
    11161 ccagaagaag tcatgggaac catccagtca gtgcttggag tattcaatgt tgttgtacca
    11221 ggaattctta gcatgctcat cgttgcctta gcgagtgcta caaacctaaa aatcacagtg
    11281 cttccacttt ttatttttgt attgactgcc ttagcaattg tgaaagcaat gaaaatagag
    11341 taatagtagt atgaactact gtctcttttt gggtgggagt tcattaccca tcagacgtcc
    11401 ttgccagtct ctgtgtgggc ttgggagttt tgtttatcga gtttcccttc tatgacaagc
    11461 tccgcttcca atggcgattt aaaggcaaac agaagtgagt atcgaattcc cttgaggaga
    11521 aagaaatgaa agtcaatata gcagatcttc atccgactca actatattta tcagaaaaga
    11581 agttgcaaga tattcagatg ctttaccagt cggcagaaac aatccaagtc gatccaatca
    11641 gtattcttgc ctttggagat tgtttgctga ttacagatgg gcatcacagg gcttatcagg
    11701 ctttattggc aggtcgggat acgatttctg ctgagtggga tagagatggt ggtgatgaac
    11761 tatatcatct ctatgcgcaa gcttgcgagg aaagaaagat ttactctgtt tttgatttaa
    11821 aaaatcatat cttacctctt tggatcggca tggtgagctt tttttgattg aagtcaagga
    11881 gaagggagaa tggtttccaa ttggggatat tacactatct caggataatc tccccattgt
    11941 gattgggaat tccgcttacc aacatcgagg acttggaaaa aagattctaa gtgctttgat
    12001 tgaattggct cgagtaaaag gatggaaaga attgagagtc aaggaaatct acacctacaa
    12061 tcatgcttct aggaggtgtt tcaagtcgct tggatttgtg gaaaatggag caacagaaaa
    12121 aggaaggagt tttatattgg aattagtcta atcctgccac tttctccccc ttaacctttg
    12181 actattccgc aaaattatcg taaaataaag agtaaatgat aaaatgaggt cagagtctgt
    12241 tcgctctgac gatagtagta taaatgagga gaaacgcttt ggaattagaa gtatttgctg
    12301 ggcaagaaaa aagtgaacta tctatgattg aggtagcgcg tgctatatta gaacttcgtg
    12361 gtcgcgatca tgagatgcat tttagcgatc ttgtaaacga aattcaaaac taccttggaa
    12421 catcaaacag cgatatccgc gaagctttgc ctctgttcta cacagagttg aactttgacg
    12481 gtagcttcat ctcacttggg gacaacaaat ggggtcttcg ttcatggtat ggtgtggacg
    12541 aaatcgacga agaaatcatc gctcttgaag aaaatgacga cgatgaagta gcaccaaaag
    12601 ctaagaaaaa acgtgtcaat gcctttatgg atggtgattc agatgccatt gactacaatg
    12661 cagatgatcc agaagacgaa gatgcatacg aagcagatcc agctctttca tacgatgatg
    12721 aaaatccaga tgatgaaaaa aatgaagtgg aagcttatga tgcagaaatc aacgaaatcg
    12781 ctccagatga cttgggagaa gatgtggatc tcaacgaaga cgacgacgag ttttcagatg
    12841 acgacgctga aaccagcgag gaataagagt tagctattga caattatcct atttttaggt
    12901 atcatattgt ttgggcacct cttttagagg tcggggctcc ctagttctta gggagctatt
    12961 tttgtttttt caagaagtta tcttcttgta ttttatactc aatgaaaatc aaagagcaag
    13021 ctaggaaact ggccgtaggc tgctcaaaac actgttttga ggttgtagat aagactgaca
    13081 aagtcaggaa cacatatcta cggcaaggcg acgttgacgc ggtttgaaga gattttcgaa
    13141 gagtattagt tgtgaatctg gtgcagtcgt cccagattat tcttattagt agggtcttgt
    13201 tttctatatc ccctcgtagt taacaagacc ttgagcattt tagaaagagg aatctatgtc
    13261 tacgaaatat atttttgtaa ctggtggtgt ggtatcgtct attgggaaag ggattgtggc
    13321 agcgagtcta ggccgtctct tgaaaaatcg tggtctcaaa gtaaccattc aaaagtttga
    13381 cccttatatc aatattgatc cgggaaccat gagtccttac cagcacgggg aagtttttgt
    13441 gacagatgac ggagctgaga cagatttgga cttgggtcac tatgaacgtt tcatcgatat
    13501 caatctcaac aaatattcca acgtgacaac tgggaaaatt tacagtgaag ttcttcgtaa
    13561 agaacgccgt ggagaatacc ttggggcaac tgttcaagtc attcctcata tcacagatgc
    13621 tttgaaagaa aaaatcaagc gtgccgctct aacgaccgac tctgatgtca ttatcacaga
    13681 ggttggtgga acagtaggag atatcgagtc cttgccattc ctagaggctc ttcgtcagat
    13741 gaaggcagat gtgggtgcgg ataatgtcat gtatatccat acaaccttgc ttccttacct
    13801 caaggctgct ggtgaaatga aaaccaaacc aacccaacac tctgtcaaag aattgcgtgg
    13861 cttgggaatc caaccaaata tgttggttat tcgtacagaa gagccagctg gtcaaggaat
    13921 taaaaataaa ctggcccagt tctgtgatgt ggcaccagaa gccgttatcg aatcgttgga
    13981 tgttgaacac ctttaccaaa ttccactgaa cttgcaggca caagggatgg accaaattgt
    14041 ttgtgatcat ttgaaattag acgcaccagc agcggatatg acagaatggt cagccatggt
    14101 ggacaaggtc atgaacctca agaaacaagt taagatttcc cttgttggta agtatgtgga
    14161 gttgcaagat gcctatatct cagtggtcga agccttgaaa cactctggct atgtcaatga
    14221 tgtagaagtt aaaatcaatt gggtcaatgc caatgatgtg acagcagaga atgtagcaga
    14281 actcttgtct gatgcggacg ggatcatcgt accaggtggt tttggtcaac gtggtacaga
    14341 agggaaaatc caagccatcc gctatgcgcg tgaaaatgat gttccaatgt tgggagtctg
    14401 cttgggaatg cagttgacat gtatcgagtt tgctcgtcac gttttaggtc ttgaaggtgc
    14461 caattctgca gagcttgcac cagaaacaaa ataccctatc attgatatca tgcgtgatca
    14521 gattgatatt gaggatatgg gtggaaccct tcgtttggga ctttatccgt ctaagttgaa
    14581 acgtggctct aaggctgctg ctgcttatca caatcaagaa gtggtgcaac gccgtcaccg
    14641 tcaccgttat gagtttaata atgccttccg tgagcagttt gaggcagcag gttttgtctt
    14701 ttcaggagtt tctccagaca atcgtttggt agaaatcgtg gaaattcctg aaaataaatt
    14761 ctttgtagct tgtcagtatc accctgaact gtcaagccgt ccaaaccgac cagaagaact
    14821 ctacactgcc tttgttactg cagcggttga gaacagcaat tagcaaaatc agaacctttg
    14881 agaaaaatct cagaggtttt ttgcatacga tgatattgca atatatctga ggtagggggc
    14941 ctctgtatgt acctgctacc gttgaaatca atagcgactc cctcttgccc tgtgctagtg
    15001 aatggattta tcagtatatt gaaatgaaat aaaatttgaa caaattaatt cggaaagcca
    15061 aatcaatttc tagcaaagtt ttaggaactg gattgtatag tgaattgaaa taagatgtga
    15121 acatctctat cagaaaagtc aaattaattt atagaaatat tttagcagtc aagatgtact
    15181 gttatagatt caatacatta tactttttta atttaatcca ctatagtaaa atgaaataag
    15241 aacaggacaa atcgatcagg acagtcaaat cgatttctaa caatgtttta gaaatagagg
    15301 tgtactattc tagtttcaat atactatata tctgcagaat actctttcag tttcattcag
    15361 cctagtcttg cttaggaaaa agtaaaaagc catccaatta tgatggatag cttcttggtt
    15421 cttagatttg ttctgcaaaa accttttcag caaggttcat agcgtggtct gatacacgag
    15481 tgtagtgtga gatgatgtcg ataaagttga ccccagcttg tgttgaacat tcgcctttgt
    15541 tgaggcgttt gatgtgggtt tttctgagaa cacgttctat cttattgatt gcttcatgac
    15601 gttctacaag actgcgtgct ttttcaatat cattgttttc cacactatcc agagcatctt
    15661 tgataaagtc actagtttgg cggtaaactt cctctaattc tttcaaggcg gcatcagaaa
    15721 attcaacatt tttccgttga agatagtcag tcagattgag tagagcctcc gtgtggtctc
    15781 caatccgttc caaatcacgg gaggaatcaa ggatattggt aagcacttca ctttcttttt
    15841 ggctgagagc ttcgcttgaa agggcaatga gataacgtgt taattgctca tcgatggtgt
    15901 taattgcttc ttcggtttta tgcccttttt cagcaacttt ttcatccaag tcaatgatgt
    15961 acttatagga aaggtcaaag gctttagcag cgtagtttcc taagtgcaag agctctttct
    16021 tagcatttcc tagagcgata gatggggcct gtttgatgaa atgttcatca agatataagg
    16081 gttcgtattt gacaacctcg tcctctccag gaataatctt ggttacaaag taagccagag
    16141 ctccgataaa tggaaattgg acaatggtgt tggtaatatt aaaggttccg tgagcaaagg
    16201 cgatggtcat ttccggtgct agatttagcg tagcttcaaa ccaatgaatc aggacagtaa
    16261 aaggaactag aaaaataacg cagacgactg ttccgataac gttgaaggca acatgagctc
    16321 ctgctacccg tttagctgca atattagccc ctaaagaggc aatgatggct gtaatggtta
    16381 tcccgatatt gtcaccaaat agaactggca aagctccctg taggtcaatt agattgccgg
    16441 cgtagaggtt ttgtaaaatc ccaatggtag ccgaagaagc ttgaattagc aaggtcaagc
    16501 cggtaccgac aaagacaccc aaaacaggat tcttacttag ctcaatcata tagtccttaa
    16561 agacctgtaa atccttgagt ggagccattg cgccgctcat gagattgagg gcaaaaaaga
    16621 taccaccgac accaaagagg atgcgtccga tattattgac tgtccgattt tttgtaaaaa
    16681 agagacagac ggcaccgata aagagcatag gtagggcata gttacctaat ttaaaaccga
    16741 tgagaaagga tgtgacagtt gtcccaatat tagcacccat gacaatcccg atagcctgac
    16801 gtaaggttaa gagaccggca ctgaccaggc cgactgtgat aactgttaca ccagaactag
    16861 actgaattag agcagtcatc ccaataccaa ccagaactcc aaagaaagga ttactagtat
    16921 atttgtcaat gtaaaaacga aggcgatctc cagcagcttg ttgcaaaccg tctcccatgg
    16981 tcttgatgct atataagaat agccccagac cacctaaaaa gtgaaataaa atttcctgcc
    17041 aattaatgga catttctttt tcctccgaaa aataatcgcg gaatatcttc tattctattt
    17101 taaaggataa aagtaaatct aacaagtgtt aatgtcaagt ttgtaaaaga aaattataat
    17161 tgataagtgt attattttta agagttttta accttatttt agatttgtgc aaacagttat
    17221 tgttttttgt ctaaaaatgt tttaggataa aaatgtgatt atcatggttc tagagtttga
    17281 taaaaaacta cagaatataa agcgctttct tgaaaacaac aaaatcaatc ttttaggagg
    17341 agaaaatgaa gaatccattt tttgaaagac gttgtcgtta cagtattcgt aagttatcag
    17401 taggagcctg ctcgctgatg attggtgctg ttttatttgc tggtccagcc ttggctgaag
    17461 aaactgcagt tcctgaaaat agcggagcta atacagagct tgtttcagga gagagtgagc
    17521 attcgaccaa tgaagctgat aagcagaatg aaggggaaca tgctagagaa aacaagctag
    17581 aaaaggcaga aggagtagcg atagcatctg aaactgcttc gccagcaagc aatgaagctg
    17641 caactactga aactgcagaa gcagctagcg cagctaaacc agaggaaaaa gcaagtgagg
    17701 tggttgcaga aacaccatct gcagaagcaa aacctaagtc tgacaaggaa acagaagcaa
    17761 agcccgaagc aactaaccaa ggggatgagt ctaaaccagc agcagaagct aataagactg
    17821 aaaaagaagt ccagccagat gtccctaaaa atacagaaaa aacattaaaa ccaaaggaaa
    17881 tcaaatttaa ttcatgggaa gaattgttaa aatgggaacc aggtgctcgt gaagatgatg
    17941 ctattaaccg cggatctgtt gtcctcgctt cacgtcggac aggtcattta gtcaatgaaa
    18001 aagctagcaa ggaagcaaaa gttcaagcct tatcaaacac caattctaaa gcaaaagacc
    18061 atgcttctgt tggtggagaa gagttcaagg cctatgcttt tgactattgg caatatctag
    18121 attcaatggt cttctgggaa ggtctcgtac caactcctga cgttattgat gcaggtcacc
    18181 gtaacggggt tcctgtatac ggtacactct tcttcaactg gtctaatagt attgcagatc
    18241 aagaaagatt tgctgaagct ttgaagcaag acgcagatgg tagcttccca attgcccgta
    18301 aattggtaga catggccaag tattatggct atgatggcta tttcatcaac caagaaacaa
    18361 ctggagattt ggttaaacct cttggagaaa agatgcgcca gtttatgctc tatagcaagg
    18421 aatatgctgc taaggtaaac catccaatca agtattcttg gtacgatgcc atgacctata
    18481 actatggacg ttaccatcaa gatggtttgg gagaatacaa ctaccaattc atgcaaccag
    18541 aaggagataa ggttccggca gataacttct ttgctaactt taactgggat aaggctaaaa
    18601 atgattacac tattgcaact gccaactgga ttggtcgtaa tccttatgat gtatttgcag
    18661 gtttggaatt gcaacagggt ggttcctaca agacaaaggt taagtggaat gacattttag
    18721 acgaaaatgg gaaattgcgc ctttctcttg gtttatttgc cccagatacc attacaagtt
    18781 taggaaaaac tggtgaagat tatcataaaa atgaagatat cttctttaca ggttatcaag
    18841 gagaccctac tggccaaaaa ccaggtgaca aagattggta tggtattgct aacctagttg
    18901 cggaccgtac gccagcggta ggtaatactt ttactacttc ttttaataca ggtcatggta
    18961 aaaaatggtt cgtagatggt aaggtttcta aggattctga gtggaattat cgttcagtat
    19021 caggtgttct tccaacatgg cgctggtggc agacttcaac aggggaaaaa cttcgtgcag
    19081 aatatgattt tacagatgcc tataatggcg gaaattccct taaattctct ggtgatgtag
    19141 ccggtaagac agatcaggat gtgagacttt attctactaa gttagaagta actgagaaga
    19201 ccaaacttcg tgttgcccac aagggaggaa aaggttctaa agtttatatg gcattctcta
    19261 caactccaga ctacaaattc gatgatgcag atgcatggaa agagctaacc ctttctgaca
    19321 actggacaaa tgaagaattt gatctcagct cactagcagg taaaaccatc tatgcagtca
    19381 aactattttt cgagcatgaa ggtgctgtaa aagattatca gttcaacctc ggacaattaa
    19441 ctatctcgga caatcaccaa gagccacaat cgccgacaag cttttctgta gtgaaacaat
    19501 ctcttaaaaa tgcccaagaa gcggaagcag ttgtgcaatt taaaggcaac aaggatgcag
    19561 atttctatga agtttatgaa aaagatggag acagctggaa attactaact ggctcatctt
    19621 ctacaactat ttatctacca aaagttagcc gctcagcaag tgctcagggt acaactcaag
    19681 aactgaaggt tgtagcagtc ggtaaaaatg gagttcgttc agaagctgca accacaacct
    19741 ttgattgggg tatgactgta aaagatacca gcctaccaaa accactagct gaaaatatcg
    19801 ttccaggtgc aacagttatt gatagtactt tccctaagac tgaaggtgga gaaggtattg
    19861 aaggtatgtt gaacggtacc attactagct tgtcagataa atggtcttca gctcagttga
    19921 gtggtagtgt ggatattcgt ttgaccaagc cacgtaccgt tgttagatgg gtcatggatc
    19981 atgcaggagc tggtggtgag tctgttaacg atggcttgat gaacactaaa gactttgacc
    20041 tttattataa agatgcagat ggtgagtgga agctagctaa ggaagtccgt ggtaacaaag
    20101 cacacgtgac agatatcact cttgataaac caatcactgc tcaagactgg cgcttgaatg
    20161 ttgtcacttc tgacaatgga actccatgga aggctattcg tatctataac tggaaaatgt
    20221 atgaaaagct tgatactgag agtgtcaata ttccgatggc caaggctgca gcccgttctc
    20281 taggcaataa caaggtacaa gttggctttg cagatgtacc ggctggagca actattaccg
    20341 tttatgataa tccaaattct caaactccgc tcgcaacctt gaagagcgaa gttggaggag
    20401 acctagcaag tgcaccattg gatttgacaa atcaatctgg tcttctttat tatcgtaccc
    20461 agttgccagg caaggaaatt agtaatgtcc tagcagtttc cgttccaaaa gatgacagaa
    20521 gaatcaagtc agtcagccta gaaacaggac ctaagaaaac aagctacgcc gaaggggagg
    20581 atttggacct tagaggtggt gttcttcgag ttcagtatga aggaggaact gaggacgaac
    20641 tcattcgcct aactcacgca ggtgtatcag tatcaggttt tgatacgcat cataagggag
    20701 aacagaatct tactctccaa tatttgggac aaccagtaaa tgctaatttg tcagtgactg
    20761 tcactggcca agatgaagca agtccgaaaa ctattttggg aattgaagta agtcaggaac
    20821 cgaaaaaaga ttacctagtt ggtgatagct tagacttgtc tgaaggacgc tttgcagtgg
    20881 cttatagcaa tgacaccatg gaagaacatt cctttactga tgagggagtt gaaatttctg
    20941 gttacgatgc tcaaaagact ggtcgtcaaa ccttgacgct tcgttaccaa ggtcatgaag
    21001 tcaactttga tgttttggta tctccaaaag cagcattgaa cgatgagtac ctcaaacaaa
    21061 aattagcaga ggttgaagct gctaagaaca aggtggtcta taactttgct tcaccagaag
    21121 taaaagaagc tttcttgaaa gcaattgaag cggccgaaca agtgttgaaa gaccatgaaa
    21181 ctagcaccca agatcaagtc aatgaccgac ttaataaatt gacagaagct cataaagctc
    21241 tgaatggtca agagaaattt aaggaagaaa agacagagct tgatcgttta acaggtgagg
    21301 ttcaagaact cttggctgcc aaaccaaacc atccttcagg ttctgcccta gctccgcttc
    21361 ttgagaaaaa caaggccttg gttgaaaaag tagatttgag tccagaagag cttgcaacag
    21421 cgaaacagag tctaaaagat ctggttgctt tattgaaaga agacaagcca gcagtctttt
    21481 ctgatagtaa aacaggtgtt gaagtacact tctcaaataa agagaagact gtcatcaagg
    21541 gtttgaaagt agagcgtgtt caagcaagtg ctgaagagaa gaaatacttt gctggagaag
    21601 atgctcatgt ctttgaaata gaaggtttgg atgaaaaagg tcaagatgtt gatctctctt
    21661 acgcttctat tgtgaaaatc ccaattgaaa aagataagaa agttaagaaa gtatttttct
    21721 tacctgaagg caaagaggca gtagaattgg cttttgaaca aacggatagt catgttatct
    21781 ttacagcacc acactttact cattatgcct ttgtttatga atctgctgaa aaaccacaac
    21841 ctgctaaacc agcaccacaa aacaaagtcc ttccaaaacc tacttatcaa ccggcttctg
    21901 atcaacaaaa ggctcctaaa ttggaagttc aagaggaaaa ggttgccttt catcgtcaag
    21961 agcatgaaaa tgctgagatg ctagttgggg aacaacgagt catcatacag ggacgagatg
    22021 gactgttaag acatgtcttt gaagttgatg aaaacggtca gcgtcgtctt cgttcaacag
    22081 aagtcatcca agaagcgatt ccagaaattg ttgaaattgg aacaaaagta aaaacagtac
    22141 cagcagtagt agctacacag gaaaaaccag ctcaaaatac agcagttaaa tcagaagaag
    22201 caagcaaaca attgccaaat acaggaacag ctgatgctaa tgaagcccta atagcagtct
    22261 tagccagcct tggtcttgct agtttagcct tgaccttgag acggaaaaga gaagataaag
    22321 attaaatatc gaaaaatctt gtgaaatctt tccttatatt tccaaagtgt gatataatag
    22381 tttcgaataa aataaataaa ggagtttttg taacatggca aaacttactg ttaaagacgt
    22441 tgacttgaaa ggtaaaaaag tcctcgttcg tgttgacttc aacgtaccat tgaaagatgg
    22501 cgtaatcact aacgataacc gtatcacagc agctcttcca actattaagt acatcatcga
    22561 acaaggtgga cgtgcaattc ttttctctca ccttggacgt gtgaaagaag aagctgataa
    22621 agctggcaaa tcacttgctc ctgtagcagc tgacttggca gcaaaacttg gtcaagatgt
    22681 tgttttccca ggtgtcactc gtggtgctga attggaagcg gcaatcaacg ctcttgaaga
    22741 tggacaagtt ctcttggttg aaaacactcg ttacgaagat gttgacggca agaaagaatc
    22801 taaaaacgat cctgaacttg gtaaatactg ggcatcactt ggagatggta tcttcgtaaa
    22861 cgatgcattc ggtacagctc accgtgcaca cgcatctaac gttggtatct cagcaaacgt
    22921 tgaaaaagca gttgctggtt tccttcttga aaacgaaatt gcctacatcc aagaagcagt
    22981 tgaaactcca gaacgtccat tcgtggctat ccttggtggt tcaaaagttt cagacaagat
    23041 cggtgttatc gaaaacttgc ttgaaaaagc tgataaagtc cttatcggtg gtgggatgac
    23101 ttacacattc tacaaagcac aaggtatcga aatcggtaac tcacttgtag aagaagacaa
    23161 attggatgtt gcgaaagctc ttcttgaaaa agcaaatggt aaattgatct tgccagttga
    23221 ctcaaaagaa gctaacgcat ttgctggtta cactgaagtg cgtgacactg aaggtgaagc
    23281 agtttctgaa ggcttccttg gtcttgacat cggtccaaaa tctatcgcca aatttgacga
    23341 agctttgact ggtgccaaaa cagttgtatg gaacggacct atgggtgtat ttgaaaaccc
    23401 agatttccaa gctggtacaa tcggtgtgat ggacgctatc gtgaaacaac caggagttaa
    23461 atcaatcatc ggtggtggtg actcagctgc cgcagcgatt aaccttggcc gtgcagacaa
    23521 gttctcatgg attagtacgg gtggtggagc atcaatggaa cttcttgaag gtaaggttct
    23581 tccaggactt gcagccttga cagaaaaata agattttata aacaaatcaa agaagagagg
    23641 gatgaaagtt cctcttttct tttgcttaaa ataaaaacgc ttcctctcaa ctattactca
    23701 taaaaatcac cgatttatga taaaatggaa atagaaagtt gagattatga gttattttaa
    23761 aaaatataaa ttcgataaat cccagttcaa acttggtatg cgaaccttta aaacaggtat
    23821 tgctgttttt ctagttctct tgatttttgg cttttttggc tggaaaggtc ttcaaattgg
    23881 tgctttgaca gccgttttta gcctgaggga gagttttgat gagagtgttc attttgggac
    23941 ttcgcgtatt ctaggaaata gtatcggtgg actctatgcc ttggtcttct tcttattaaa
    24001 tacttttttc cacgaagcct tttgggtgac cttggtagtt gttccaatct gcaccatgtt
    24061 aaccattatg acaaatgtag ccatgaataa caaagcaggg gttattggtg gtgtagcagc
    24121 tatgttaatc attaccctat caattccaag tggtgagaca attttgtacg tgtttgtgcg
    24181 tgtattagaa acgtttatgg gagtttttgt cgcaattatc gtaaattacg atattgatcg
    24241 tattcgtctc tttttagaga aaaaagaaaa ataatgttac attttataac attatcaatt
    24301 gacgtttgtc tttttttaga ctataataga cagaaagaag gaaattgtaa atgaaggaaa
    24361 aagaatttcg ccgaaatatg gctgtttttc ctatcggcag tgttatgaag ttgaccgatt
    24421 tatcggcgcg tcagattcgt tattatgaag atcaagagtt gatcaagccc gatcgaaacg
    24481 aaggaaatcg tcgcatgtat tccttgaatg acatggatcg tctgcttgaa atcaaagatt
    24541 atatctctga aggttataat atcgctgcca ttaagaaaaa atatgctgaa cgtgaagcga
    24601 aatccaagaa agcggttagt cagactgaag tacgtcgtgc acttcacaat gaactcctcc
    24661 aacaggggcg ttttgcttca gtacagtcac cttttggtcg cggttaggca accgcaagta
    24721 gtcatagatt aaggagaaaa cttatgccaa tcacagctgc agatattcgt cgtgaagtca
    24781 aggaaaaaaa tgttaccttt attcgtctta tgttctcaga tattttggga accatgaaaa
    24841 acgtcgaaat tcctgctaca gatgaacagt tagataaggt cttgtcgaac aaggttatgt
    24901 ttgatggatc ttctattgaa ggttttgtac gtatcaatga gtcggatatg tacttgtacc
    24961 cggacttgga tacatggaca gtcttccctt ggggagatga aaatggaagt gttgcaggtc
    25021 tgatctgtga tgtctataca acagaaggtg aaccatttgc gggtgaccct cgtggtaatt
    25081 tgaaacgagc tcttcgtcac atggaagaag ttggattcaa atccttcaac cttggtccag
    25141 agccagaatt cttcctattt aagttggatg aaaatgggga cccaacactt gaagtgaatg
    25201 acaagggtgg ctactttgat ttggcaccta ctgaccttgc ggacaacaca cgtcgtgaga
    25261 ttgtgaatgt cttgaccaaa atgggatttg aagtagaagc gagtcaccac gaggttgcgg
    25321 ttggacagca tgagattgac tttaagtacg atgaagttct ccgtgcttgt gataagattc
    25381 aaatctttaa gcttgttgtt aaaaccattg ctcgcaaaca cggactttac gcaacattta
    25441 tggcgaagcc aaaatttggt attgctggat caggtatgca ctgtaatatg tccttgtttg
    25501 atgcagaagg aaataacgcc ttctttgatc caaatgatcc aaaaggaatg cagttgtcag
    25561 aaacagctta ccatttccta ggcggtttga tcaagcatgc ttacaactat actgccatca
    25621 tgaacccaac agttaactca tacaaacgtt tggttccagg ttatgaagcg cctgtttaca
    25681 ttgcttgggc tggtcgtaac cgttcgccac ttgtgcgcgt acctgcttca cgtggtatgg
    25741 gaactcgtct tgagttgcgt tcagtggatc caatggcgaa cccttacatt gctatggctg
    25801 ttcttttgga agttggtttg tatggtattg aaaataaaat cgaagcacca gctcctatcg
    25861 aagaaaatat ctacatcatg acagcagaag agcgcaagga agctggtatt acagaccttc
    25921 catcaactct tcacaacgct ttgaaagctt tgacagaaga tgaagtggtt aaagctgctc
    25981 tcggagatca catctacact agcttccttg aagccaaacg aatcgaatgg gcaagttatg
    26041 caaccttcgt ttcacaatgg gaaattgata attatttaga cctttactaa tactaatata
    26101 gaagaaagat tgcctgtggg taaacagtca cacagcagtc taagccatca aatacctata
    26161 acccttaaaa tagcgatttc ggtcgctatt tatttttcga aaaatcctct tgactctttt
    26221 gcgaattaga tttatcatca gacgtgtaga agaaaatcaa ggagtcacta tggaaaaatt
    26281 caatttcaaa aacaatatcg ggcaagaaaa caagttactt caaatcgaaa tctacaagtt
    26341 tactaacttt tgcaagcttc aaaattacac atctgtaaat attttttcga aagatatatt
    26401 tgaagccata gtaaattgag actagaatag tacactacat ctgctaaaaa tttctagaaa
    26461 ttaatttaac tttcctaatc gatttgttta catcttattt caatctacta tattatctca
    26521 ataaatgatg atggcgactg ttttgtttgt gcttgtcgat ttttgaatcc tgatcgagcg
    26581 gaagaatatt tctgccgagg ttgtcaaggg gaaaatcctg aagatattga attttatgat
    26641 gaacaattac aggcagaaaa ggtggaggct ttgaatattc gattggaagt aaaaaattga
    26701 attatctaca atctcatcaa caataaacct atttcaaccc cattatctat aggcgtattt
    26761 ttacgccttt ttatatactt gaagcacata agaaacatta tgggaagttt gctgatggaa
    26821 gtactcaaga aattgatgtt ccttatgata ttcctgatac ttgggagtgg gtgaggataa
    26881 aatcaattta ttggaatttt gggcaaaata agccagagaa atcctttagg tatatagata
    26941 cgtctagtat tgatagaaaa aagaacataa tcaactacaa aaatctacaa tatctttcac
    27001 ctgaacaagc gccttcccgt gccagaaaat tagtttcgca gaatagtgtc ttattttcaa
    27061 cagttagacc atatctaaaa aatattgctg tagttagaga acttaaagag tatttgatag
    27121 ctagtacagc atttattgtt ttggatactt tacttaacga aacatatttg aaatattatt
    27181 tattatcaga taattttatc aatcgtgtta ataataaatc tactggaaca agttatcctg
    27241 caatcaatga ttataatttt aatctattat taatt
//
LOCUS       DAVBEM010000030        25970 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVBEM010000030 DAVBEM010000000
VERSION     DAVBEM010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25970
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.030"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(240..491)
                     /locus_tag="VQ548_001270"
     CDS             complement(240..491)
                     /locus_tag="VQ548_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654116.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYIENVYLDSLSVKQKFKFIFDFGDEWRFEC"
     gene            complement(781..2661)
                     /locus_tag="VQ548_001271"
     CDS             complement(781..2661)
                     /locus_tag="VQ548_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET2654117.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(2655..3524)
                     /locus_tag="VQ548_001272"
     CDS             complement(2655..3524)
                     /locus_tag="VQ548_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2654118.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPDLENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNILCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQDVKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(3608..6253)
                     /locus_tag="VQ548_001273"
     CDS             complement(3608..6253)
                     /locus_tag="VQ548_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HET2654119.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDERFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAFRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVFRYYNMSQENVHISEHQQTILDLLE
                     RPYPVHSGPLDPQEIRTEFIKKEEI"
     gene            complement(6344..7624)
                     /locus_tag="VQ548_001274"
     CDS             complement(6344..7624)
                     /locus_tag="VQ548_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HET2654120.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSIDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            7795..9879
                     /locus_tag="VQ548_001275"
     CDS             7795..9879
                     /locus_tag="VQ548_001275"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HET2654121.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGKAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKENKWLDIHTEQNHSHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPNH"
     gene            complement(9919..11598)
                     /locus_tag="VQ548_001276"
     CDS             complement(9919..11598)
                     /locus_tag="VQ548_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HET2654122.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNLDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFDCRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIYVLAFQAGETEKRLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            12353..13582
                     /gene="arcA"
                     /locus_tag="VQ548_001277"
     CDS             12353..13582
                     /gene="arcA"
                     /locus_tag="VQ548_001277"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HET2654123.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELILSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGNLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            13640..14656
                     /gene="argF"
                     /locus_tag="VQ548_001278"
     CDS             13640..14656
                     /gene="argF"
                     /locus_tag="VQ548_001278"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HET2654124.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            14821..15768
                     /gene="arcC"
                     /locus_tag="VQ548_001279"
     CDS             14821..15768
                     /gene="arcC"
                     /locus_tag="VQ548_001279"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HET2654125.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVIVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            15977..17488
                     /locus_tag="VQ548_001280"
     CDS             15977..17488
                     /locus_tag="VQ548_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HET2654126.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNTWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            17510..18841
                     /locus_tag="VQ548_001281"
     CDS             17510..18841
                     /locus_tag="VQ548_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HET2654127.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAEDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(19247..19537)
                     /locus_tag="VQ548_001282"
     CDS             complement(19247..19537)
                     /locus_tag="VQ548_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654128.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(19525..19776)
                     /locus_tag="VQ548_001283"
     CDS             complement(19525..19776)
                     /locus_tag="VQ548_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET2654129.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGDQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            complement(20175..21059)
                     /locus_tag="VQ548_001284"
     CDS             complement(20175..21059)
                     /locus_tag="VQ548_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET2654130.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(21204..22355)
                     /locus_tag="VQ548_001285"
     CDS             complement(21204..22355)
                     /locus_tag="VQ548_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HET2654131.1"
                     /translation="MAIFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHRCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPQALTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIEHENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(22501..24267)
                     /locus_tag="VQ548_001286"
     CDS             complement(22501..24267)
                     /locus_tag="VQ548_001286"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HET2654132.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGCAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDSGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(24324..>25970)
                     /locus_tag="VQ548_001287"
     CDS             complement(24324..>25970)
                     /locus_tag="VQ548_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET2654133.1"
                     /translation="NYRTDKTAMWALSGNFDASKSWKKEELELANWISKNYSINPVDN
                     DFRTTTLTLKGHTGHKPQINISGDKNHYTYTENWDENTHVYTITVNHNGMVEMSINTE
                     GTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVDYNGDPNRAVDGNRNGNFNSGSVTHTR
                     ADNPSWWEVDLKKMDKVGLVKIYNRTDAETQRLSNFDVILYDNNRNEVAKKHVNNLSG
                     ESVSLDFKEKGARYIKVKLLTSGVPLSLAEVEVFRESDGKQSEEDIDKITEDKVVSTN
                     KVATQSSTNYEGVAALAVDGNKDGDYGHHSVTHTKADSNAWWQVDLGEEFTVSKVDIY
                     NRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDKVVDGLLSLKVPSVGAKLVKIELKSAA
                     IPLSLAEVEAYGSKRTPKKLSNIALTKETRQSSTDYNGFSRLAVDGNKNGDYGHHSVT
                     HTKGDSPSWWEIDLAQTEELEKLIIYNRTDAEIQRLSNFDIIIYDSNNHEVFKQHIDS
                     LESNNLSIDLKGLKGKKVRISLRNAGIPLSLAEVEVYTYK"
BASE COUNT         7360 a         5804 c         5067 g         7739 t
ORIGIN      
        1 atcgaaatca tcgtaaacgc ttcggattac gaatgaattt gagtgctggt attatcaatc
       61 atgaactagg attctagttt tgcaggaagt ctattgaaat actaagccta cacagactga
      121 tttcaatttt accattcttc atagtcaaaa ccatcataat ctggatattg ttctggcaac
      181 gttccaaccg aacgtacgag ataagcttct tcgtcctctg tctcgatttc tctcagcact
      241 tagcattcaa aacgccattc atcaccgaag tcgaaaataa acttaaattt ttgtttgaca
      301 cttaggctat ccagatagac attttctatg taacgttctt caacatcgtc actaacaaag
      361 ctaagaaagt aagaatctgc atgactccac tcaacattat ccatgaaaaa tgcatgagca
      421 tgatcatttg caaaatcgaa actccataaa atcacatctg ctagttccgc taacgttttt
      481 gtttttggaa tctatatatg tcggtagcaa ccttttttaa tttgacggaa atgatccaag
      541 cttctacaga tgctggcttt tcagcttcta tttcttgttt tactaatttt aactgtagca
      601 tttgaaacca gataattctt ctgtttcacg cgaaacaccc tgcgccaagc aaggtgttct
      661 tgtttttata ctcaatgaaa atcaaagagc aaactaggaa gctagctgca ggctgctcaa
      721 aacactgttt tgaggttgta gatggaagct gacgtggttt gaagagattt tcgaagagta
      781 ttaagtcgta taaatcgtcg aagctgtcgc aatggtatgc cactggttag ctgtagttgc
      841 tgcgaaatcc ttgtctgcgt agaagtcagt aaatggtagg atttcaactt ccagctcgtc
      901 gatgcggtca agctggccag ccagataaac ctcgatacgg ctttctgctc gtttgatgcg
      961 ttgcaagagt ccgcccatac ggatgtcaac tgtatccaaa ccaaagacct tgttttcttt
     1021 cagccattgg tgactaaaga gggcatggaa gtcttcaatt tggcttctaa gttctggtaa
     1081 ttcttgtctg gcgatttgtt gtaaactttc tttatcatcc gcttggtagg cctgacgaat
     1141 gcgtcgtccc acatctactt tgctacttaa aatagcattc aactgggcct gagtttcaaa
     1201 gagataagca tagtttccag ctttttcttt aatgttagca agcgtctcag cagcctgagc
     1261 gaagtgcggt ttgtcctgtt caggtgtcat gtgttgatca agaatcggac aaagaatatc
     1321 ctgataaaaa acatagcggt tgggattgat accgctgaga ttgcctggta ggtctggtaa
     1381 gaggttggca aggtcaatct gcataaaatc ctcaaccgtt agaccagtat tggtcttgaa
     1441 gtgcgcagac aaaccatcta ggtcattgcg atagctgagt tctgcccaga tttgcaagct
     1501 tggtaggata gagaactggg cagtttcacc accattgtct ccccaacccg ttacgatgac
     1561 ttctttaatc tgattggcac ggcaggcttt attagcctcg atagccacta gacggctaaa
     1621 atggttgtga ggtgtaaagc caatccactt ccaagctccc cctgcaaatg caaggtcatg
     1681 gctaatcttg tgatgattgc ggaaattacg gttgtatttt tcctcgctat cctgataata
     1741 atcccagtaa accagagtca cacggtcttt gagacggtct aggtagacac gagtttcctc
     1801 tggaatttcc acatcacggt cgtactggcc atccgctgac atgagtttga agaacatatc
     1861 actccacatc tggcagtgga aaccatattt gtcagcaata tccagcacgc gctccaagtg
     1921 ttggcacatg aggagactac gatccacaac accgttcaaa atcaggtagc gtcccaaacc
     1981 aaccaagtgg gcttcgtcca tcccgatatt gaccttgcga gtcttcagtt tagacaacgt
     2041 ggcaaacatg ccatcaatca ggtcataaac cttttcttcg ccaatgagaa gaatgtcctc
     2101 tacatcacgg agctcctgca cttccttgac accccatttg acaaaggccg acaagtgggc
     2161 caaggtctgg atgcatggta caaaggtcat gtcaaactgt tgagcatagg cttcgatttc
     2221 ctgcaactcc tctgctgaat aagctccacg gaaatagcca aagtaaggct gcccttcaat
     2281 ctggtaagtg tcttccatgt aaagttcaaa ggttgagtag cccatgagag ccaagacctc
     2341 aatcatctgc ttggcagaag ccacattcag caccgcattt cgagaacagt caaccatgta
     2401 agccaaatct tcgtaagctg cttgttcctc aatctctact ttatcagctt ctgctagaac
     2461 tgttaccaac aaggataagg cacgataaag ttggtgaggt ttgcggtagg tcaattgata
     2521 gtgaccttcc tcaccctgga tagagataga ggcttggtca gactgagtga cagccacttc
     2581 cacatctggt agagaaatat gaccttttaa aacctcaata gcttgcgttt gtttgggact
     2641 aagtcctgta aatcttacca ttgcttttcc tcctgtagcc agttgacaag agcaccgtag
     2701 agattggcat ctgcgtgata ggtgcaggcc tggataactg gtgcgaccgt gtattcttcg
     2761 taggtatcga caaagttatc aacagccttc ttgacatctt ggataaaatc tggattttga
     2821 ctgatagagc cacccagact gatgacatct ggatcgatca gatactggat attgagcaag
     2881 ccttgcgcca gattgcggtt catgcgctca atggcttctt gacaaaggat attaccagct
     2941 gcggcctctt ggtaaatctt gcgaccgtcc caatcagtat gaccagattt ttcaatcacg
     3001 tatcgtacca tattcccagt tgatgctagt tgcgaccagt tattaagttt ttcagcaggg
     3061 gcaagggttg tcatgtagcc aaattctcca cccaagccgt ggcgacctcg atgaagtcta
     3121 ccattgataa tcatggctcc gccaatccct gtcccaatca cgacacaggc tgcattttca
     3181 agatctggat gagctagtag ttcactgagt ccaacgcagt tggcatcatt ttctaaatgg
     3241 acaggtagct gataagagct aagcgcctca taccaagaaa agccatggat gtagggcacc
     3301 gcactgaagc catcaatcac acctgtctct tgattgactg cacctggaac gctcatagca
     3361 atcccactgt aatcctgttc tgacaagcgt tgatctagcc acgctagtaa atcctccaag
     3421 ttttcaggcg ttgaaatact tgtcttatcc agtattttcc catcaggagt cagactggca
     3481 aacttaatcc cagtccctcc gatatcaatc gttgcaatgg tcattgtttt taccataaaa
     3541 aggggcgaat cagcagttag ttcttacttt ttcgcccctc ctttcttttg atgtttactt
     3601 tttgaaatta aatttcttct tttttgatga attctgtacg aatctcttgt ggatccaatg
     3661 gtcctgaatg aactggatat ggtcgctcaa gtaagtcaag aatggtttgt tgatgttctg
     3721 atatgtgcac attttcttga ctcatattat agtaacggaa gacatagcct tcttcatttt
     3781 ccgccacttt aaaggctgtt ggacaaactt gcggtatgct gagaacagaa tggctcaaga
     3841 ggctaccagt cgcaaccacg cttccttcct gtctagcaag ctgaaggctg gtaaacggtg
     3901 tctgcaaggc tttggcacga cggaaagctg aaaagcgttc ttgggcttgg tggcattcaa
     3961 gtgcaaactc gacttcaaac tcacgcaagc attgtgcttc tggcgttggg aagtagcccc
     4021 agtcacctag ctcacctgat gcacgcaaaa tggtcacggc aatggtgtta tccccaagga
     4081 tttcgtattc attcaatccc ttattggata cagtcacccc tttttcatcg tcatacagac
     4141 tgacaaaagc ttgttggtgt tgaggatttt caggattttc ccatgaagca gctggtttgt
     4201 ttggtcgtgt caccacctca tagatacttt cagaatcatt gcttggacgc gtgttatgag
     4261 tcttgaccaa gagacggata cggtgatcct tggcagtgtt agtaaagcga gtcttgaagc
     4321 ggatttgtgg attgtcaaca aagacaatca actcagtttc cagaggaatg tttgtcaatt
     4381 cttctgaccg tccagcctca cgcttcataa actcgatgat accttgttgc tcttcttcta
     4441 gcttttcatc cgcactgaca ggcacggtca attcatgttt gagcaagatt ttagcatagc
     4501 gatctgtgtt ttccaagacc tcgtggccct taagctctgc aaagattggc tctgttcctt
     4561 ttggttggaa atagatatac tcgtttccga tgtccccacg gtcttcgaag cggataaagt
     4621 cttcataggc ttcgtgagtt gtcttgtcat atactgtgat attgtcatcc acactcaccg
     4681 ttacgaatgg tgtatcaatc actccgtttt ggtaaatacc ctcacggtgt tcttgttttc
     4741 cttccagcaa ttggaaggtt gtccaagaaa gcggcgctag gtgaactgga atggtcacgc
     4801 gcacttgtcg agcaatacga gcttggcgga acttgtcttt tggtaaatcg tactcaaaat
     4861 tagctccgag gtcttcgatt gtagcctcta caggacgacc atccaagtcc tccacacggt
     4921 aacttggtaa gataagagca gccatctttt tgtagccttc tgttgggtgc aattccttga
     4981 aatcacaagt cgccacatca atcactgtgc tgacagtatc gaccttatca tgcaagcctg
     5041 tgttaatgac agtaaagaga tagtcacttt gagccttatc cgtagcaatt ttacccttcc
     5101 actcgttgag caagttactt ttaacaaagt ttcctacttg gttgaccttg gcaaaacgcg
     5161 tttccatctc gcggtgaact tcgtccacgc tacagccaca gatactatca tgtggcgcat
     5221 tctgcaaaag tgttttccaa gcataggtca actggtcctt gtggttgtgt ccaccagtga
     5281 taatagtcaa gggttctacc acttgctcta ggaggttgct attttcttgg aaggcttgtt
     5341 ttaggtaaat gcgggatgaa gaagtgttgg caagtgtgta ccagccatct gtttcctgac
     5401 tggtcaactc gcctgtaaca gttgataagt gttcaggaag cgcaccttct acagcttgaa
     5461 catattcatc aaaagaacta tgaacaaaga ttacatccgg gaagagttca tttgccacac
     5521 gaatggcttc gctcagattt ttctgtacag gctggtggtc acagccgttc atcatcaacc
     5581 attggttggt cgaagcgtag gcacgcacat ctgacaattt ttgtttccag aaggtcaagg
     5641 cctcatcttt gtcaactggg atttcattcc cattactgta ccagttggca aagagaatac
     5701 ctaaaacacg actaccatcc acaccctgcc agtacatttc tgaaaactgg gatgtaaacc
     5761 gctcatcttc aaggacttgg ttgtcaaatc caatcggctt cacaccacga ccaaaggctg
     5821 ccacgtgaat acctgatttt tgaaggattt gaggagcttg tcccatattt ccaaaggtat
     5881 ctggaaagta gccaatctgg gttgatttac cccatttggc agcttcttgt tgaccaatca
     5941 aggtattgcg gacattggct tcactggaga tcaagtagtc atcctgcaag atgtaaaagg
     6001 gaccaatttt aagtttgccc tcgtcaatgt agcgttggac cttgtcgcga ttttcagggc
     6061 gaatttgtaa gtagtcatca aggacaatag tttgtccatc caagtggaaa ctcttgaact
     6121 cagggtcatt ttcaaagaga tcaaagagat tgtcaaacaa ttccaccaac tgcatacgat
     6181 ggctttcaaa aggcaagtac cactcacgat cccagtgact atgtgagata atatgtacaa
     6241 caacattttc catgaagtaa aacctcattc taaatttaaa ttttaacgtt ttaaatgtaa
     6301 acttgtgatt ctgataagaa tcggttgagc taaagcgagc cccttagcgg atatccaagt
     6361 aatccaagac caactcacag aacatcatgt tagcccagga gaaccattca cgagagtaga
     6421 gggtcggatc atctacgtgg aagctttcgt gcatgacacc tgtaccacca tcgcaggcaa
     6481 ccagctgatc cagcaagaat tttttctctg ccttatctct tgttgtcaat ccttggatag
     6541 aaagggcgat tggccagata tagcgataga aggtatgaga acttccgaga ccgctagcgt
     6601 attctccttg gtagaagtat ggattttcag agctcagaat ggtacggcga gtggcttgat
     6661 acacttcatc atcgatcgaa cagtagccca gatagggcgc agctagtaga cttggtacat
     6721 ttggatcatc catgatgctg gcatttccta ggccatctac ttcaaaagcg taaatctttt
     6781 cgcccttgct gttggtggtg taagcgtagt tttcgattcc ttcttggatt tcatcctgaa
     6841 gacgcttggc atcagcaata acactctggc tatcagctag gtttaatgct gcgaagattt
     6901 cttgcacata acccaagact actacagcaa acatatttga cggaatcaag taactatact
     6961 ggcaacagtc atcactcgga cgaaaagctg accaagtcat acctgtcact gcaaagtcag
     7021 gtccaaagcc atcatttacc aaggtgtctt ccttacggtc cgtatctcgg acaaaacgat
     7081 aaggagagtt cttgtggtct tgttcaactg tccatagatg gagaatttcc ttagtcgctg
     7141 cgacaaaagt ttcatcaaac tgactagtct cgccagtctc tttccagagg agataagcca
     7201 actgcaaagg atagcaaagc gaatccacct catacttgcg ctcccagatc cagccgttaa
     7261 ggtctgtgtg gtcagtctcg tggtgccctt tccagttctc ctcaatgttg aaggagttag
     7321 catagggatc cttgagtacc aaggtcatct gacgtttgac caaacctgca atggtctgac
     7381 gcaggagggc atctctttta gctacatgaa ggtagggtct gagttgggct gtcgaatctc
     7441 gaagccacat ggcaggaata tccccagtca agacaaaagt tgaaccatct tctaagattt
     7501 caaccgtatt gtccaaggta tcggtgtagc aacgctcaaa gacatcaacc cactctggat
     7561 ggtccttggc ccgctctgct acttcatcta gccattctct aacaatttct ttcgaataaa
     7621 tcatcgtgca attccctctt tcaaacaagt ttcatgttca gtatatagct tttgagacag
     7681 aaaatacata cacaaatgat agtcattttt ctacaaaata gttatcttta aaactccttt
     7741 tctaaaggcc ctctttttct gatataatgt agaaaaacag ctaaaggaaa gactatgaaa
     7801 ccactacttg aaaccatcga tacccgcttt ggtactgcta gcaagcatgc cttctctcgg
     7861 ggaaataccc tgccatacac aggcgtgcct tttgggatga attactttgt gccccagacc
     7921 agtgaccagg atggatcttg gttttttgat ccgcatctgc ctatctttca ggggattcga
     7981 ttaactcacc agcccagtcc ttggattggg gactactctt ggctccttct gacacctgtc
     8041 accagtcaac tggggggaga cagcctcttt caccgccagt cttcttatga tatagataaa
     8101 gcttgcttcc agcctcacta tttgaagctc ttttctctgc gttatcagat tgaaacccag
     8161 ctcacaccga cttgctatgg tgcttctatt cgtttgaatc aaaagcaagg caaagccctc
     8221 tccctctatc ttcacgcagc agatgaactg acagtagagc aagtagataa gcggactctt
     8281 gccctgcgac aagaaggtaa aactgaaact aacaaaaatt cgctaacgat gttcactgcc
     8341 ctgcaaatga acacggatat tcttgctatc agccaagaag ctggggactg gcgaattgac
     8401 ttagcaagta gtcaaaccga gatgcaacta gccacttctt tcatctctcc ttctcaagct
     8461 ctaatcaatc tacctcaaga agattttgat agctgtaaaa caagtgccca agcggattgg
     8521 gaaaatctcc tccatcgttt tgacattata gagacaggag aggctgaccg aaccttcttt
     8581 gaccactgcc tctacagact cttcctcttc ccacagactt tttatgaggt tgatgagtca
     8641 gggaaagcca tccacatgga tctggctact ggtactgtca agcctggtgt cctctttagc
     8701 aacaatggtt tctgggatac cttccgcacc accttccccc tctttgccct tatcataccg
     8761 gagcactatc aacgcttttt agaaggtttc ctcaatagct accgcgatac tggtttcctt
     8821 ccaaaatggc tggctccaga tgaacggggt atgatgccag gtacactgct agatggcatt
     8881 atcgcagata gcgcctgtaa ggacatggcc cccgacctag aaggagaact cttccaagcc
     8941 atgctcgaaa cagccagcaa agccgaccct ctcggcatca atggccgcca cggactagcc
     9001 caataccaag aactaggtta cctctctacc gaccaccacg aaagtgttag ccatactcta
     9061 gactatgcct atagtgactt ttgtatcgcc agctgtgcca aaaaactaga gaacatagaa
     9121 atcgctgaaa cctacaaggc tgcttcacaa aattaccgcc agctatttga cgctgagaca
     9181 ggttacatgc gagcacgaga caatcaagga aactttcacc ctgacttctc tccttatagt
     9241 tgggggcgag actacgctga atgctctgcc attcaagcta ctttaggcgt tctccacgac
     9301 atccctggct taatccaact gatgggtgga aaagaaacct ttagcaacta tcttttgaaa
     9361 gcctgtcaag atgctcccct ctttgaaaca acaggctatg gttacgaaat tcacgaaatg
     9421 agcgagatgg ctactgctcc ttttggacaa atagccattt ccaaccagcc tagtttccac
     9481 attccttatc tcttccgcta cagcgattac cctgactaca ctgcccttct tatcaagacg
     9541 ctccgtcaga aagcttttca cccaagttgg gaagcctatc ctggagatga agacaatggt
     9601 agtctctctg cttggtacat ctggtcagct ctcggatttt atccaacctg tccaggaaaa
     9661 ccaagctatg atctcggaat ccctctcttt gaccatctac gagtctacct agctaaagaa
     9721 aataaatggc tagatattca tactgagcaa aaccacagcc attttaactt tgtcaaagaa
     9781 tgccgactgg acaaaacact cgtatcaact attcaacacc aagacctcct aaaagctgaa
     9841 caactaactt tcaccctcag ctggctacca aatcactaat aaccaaaaga acctttgcat
     9901 cgcgcaaagg ttcttctttt atgaaacttg gacttgaagt tgatccacaa gctgaccatc
     9961 caccgttagg ttcagataga aatccaaggt tttatctcct gcgaaataca aggttggtag
    10021 cgtcagcctt ttttcagtct caccagcttg aaacgcaagg acataaatct cgtcctgata
    10081 ggcgacacca tggacacctg tccccggttg aatcgaaatc ttagcctcta aagaggagct
    10141 actttcacta cgttcaatcc taaaatgaag agtctctccc tttgccacag ctaggctttt
    10201 ttctgcaaat gctagttcct gaacaacttc tttttttgat aacccaggag ttttataaag
    10261 ggaaatcttg gtcaatacag ggatagattg tgcctcggta atcatcacgc gcaccttttg
    10321 tgcctctact agcggacctc gcaagaggcg cttatgacca actgtgaagc ccctgccaaa
    10381 ctcctgccag acaccatcca cctctacttg cacatgaaaa gcagcgattc gttgccctag
    10441 cttcaaatct tctcttaact caattacatc aaaagtttta ggagaaccta aatcgagttc
    10501 taactggatg ggcaagtctg catcgcttgc ccaagagctg gtctcaaggc cgtctgtcaa
    10561 atggcgacaa tcaaagtctg cggaaagagc tggaccagat acctcagctc ccagagccaa
    10621 atcttcttta tagagctcat tgcgataggt cgcaaattca taaagtcgtt caatatcctt
    10681 tgcatcaaag agcccagctt gattcggcgg aatattaagc aagagtggag ttcctcgccc
    10741 tactgagtga aagtagattt cgaccaactc ctcgagagac ttaggatcct gatcctcatg
    10801 gtagaaccag cctggacgga tggaaacatc tgcctctccg attgaaaaaa tcgtgcccga
    10861 gggatccccg tgctgaagat agttcagctc tgcttctgtt cctagtttat caagattcac
    10921 cttttgccac agtggatcac ctgcataccc tcgttcattg ccaatccagc ggatactggt
    10981 gccttctgtt gaaaaaatca agcaatcgcc ctgcaggtca cgaatggttt caaaccattt
    11041 ttcaaattca taattaacct tttgcgcgcc ctctcctctg gcaccatcca tccaaacctc
    11101 agcgaactta ccagcattcc catagttagg atttgataag atttccttca actgagccag
    11161 ataataggca ttgtagtccg cttctcggtc cacatgatag aggggactat gggcatccca
    11221 cggtgacagg tagaccccca tatccatatc aaactctgtg gcagcttggg atacttcaag
    11281 gagcaagtcg ccctttcctc tcctccaagg actgacctta accgaataat ctgtgtgagc
    11341 tgtcggataa aggacaaagc catcgtggtg cttgaccacc aaaatcaact ttttgaagcc
    11401 cgtttccttg agcacacgaa cccactcacg cgcatccaac tgactcgggt taaagcgctc
    11461 aggatcctcc tgtccagtcc cccattcttg gtcataaaag gtattaggac cgaagtggat
    11521 aaaagctgct agttcatctc ccagataagc tagctgagtc tgacttggta acggtccatg
    11581 cggtttgatt ttcttcatcg ttatatatct ccttcttttg caacttctct tgttcacaag
    11641 gttatccaca ggttgtggat aataaaccat gatctaacag ccagctcttt ccaactccaa
    11701 ctggtaggct caggattttt ctcctcaatg ttccctcttc aaacagctct gtcatatggt
    11761 tctgctaaca cctctcagaa tgctactctc cataattatt ctcaggcttc tttcaggtca
    11821 ttgtgtgaag accattcact ctccagactt ttccacagat tgtgaataag tgattattct
    11881 aagctatcac ctcgtcgact ataacaaaaa ataaaaagag ggtcaataag ataattatct
    11941 cttcctaaat actcagaaaa gattctataa tttgtacaat tgaacaagaa atgcttctcc
    12001 aaaatctatc ttcaaaagaa tgttgcatct ttttatcctt tcacacaaac atttctcttt
    12061 atacagatcc aagtgataac cagatgataa ttggacactt tttggtcatt tgtatatttt
    12121 ttgaaaaatt ttttaaaaaa attttatatc ctttttatag aagtttatgc atttgtatct
    12181 atgtattcta tcctatgtta tgtataataa cataaaattg tgctaaacat cataatttat
    12241 attattttcc gagaaattat agccattgac attacctagg aattgcgtta taacatacat
    12301 gtaagcggta cccaaaatgg tgccaagtca aaatttttaa ggaggaaaat acatgtcttc
    12361 tcatccaatt caggtcttct cagaaattgg gaaactgaaa aaagttatgt tgcaccgtcc
    12421 aggcaaggag ttagaaaact tgttgccgga ctatcttgaa aggcttcttt ttgatgatat
    12481 tcctttcttg gaagatgctc aaaaagaaca tgatgcattt gcccaagctc ttcgcgatga
    12541 aggaattgag gttctctacc tagaacaact cgctgctgaa tcattgacct ctccagaaat
    12601 ccgcgatcaa tttatcgagg aatacttaga cgaagccaac atccgtgatc gtcaaaccaa
    12661 ggttgctatt cgtgaattac ttcacggcat caaggacaac caagaattgg ttgaaaaaac
    12721 aatggctggg attcaaaaag ttgaattgcc agaaattcct gacgaagcta aagatctaac
    12781 tgacttagtt gaatcagatt atccatttgc aattgacccg atgccaaacc tctatttcac
    12841 tcgcgaccca tttgcaacaa ttggaaacgc cgtatcgctt aaccacatgt ttgcagatac
    12901 tcgtaaccgt gaaacactct acggtaagta tatcttcaaa taccacccaa tctatggcgg
    12961 aaaagtggat ttggtctaca accgtgaaga agatacgcgt atcgaaggtg gagacgagct
    13021 aattctttct aaagacgtcc ttgcagtagg tatctctcaa cgtacagacg cagcttctat
    13081 cgaaaaactt ttggtcaaca tcttcaagaa aaatgttggc ttcaagaaag ttttggcctt
    13141 tgaatttgct aacaaccgta aattcatgca cttggatact gtcttcacta tggtagacta
    13201 tgacaagttc actattcacc cagaaatcga aggcaacctt cacgtttact cagttactta
    13261 cgaaaacgaa aaacttaaaa ttgttgaaga gaaaggtgac ttagctgaac ttcttgctca
    13321 aaaccttggt gtagaaaaag ttcatttgat tcgttgcggt ggtggcaata tcgtagcagc
    13381 tgcgcgtgaa caatggaacg acggttctaa cactttgacc atcgcacctg gtgtggtagt
    13441 tgtttatgac cgcaataccg tgaccaataa gattttggaa gaatacgggc ttcgcttgat
    13501 taagattcgc ggaagtgaat tggttcgggg ccgtggtgga cctcgttgta tgtctatgcc
    13561 atttgaacgt gaagaagtgt aatcgctgtt cggtattcgt caatagaaaa tgtaaaaaat
    13621 agaaagagga aataataaaa tgacaaattc agtattccaa ggacgcagct tcttagcaga
    13681 aaaagacttt acccgtgcag agttagaata ccttattggt ctttcagctc acttgaaaga
    13741 tttgaaaaaa cgcaatattc aacaccacta ccttgctggc aagaatatcg ctctcctatt
    13801 tgaaaaaaca tctactcgta ctcgtgcagc ctttacaact gcggctatcg accttggtgc
    13861 tcacccagaa tacctcggag caaatgatat tcagttgggt aaaaaagaat ctactgaaga
    13921 tactgctaaa gtattgggac gtatgtttga cgggattgaa ttccgcggat tcagccaacg
    13981 tatggttgaa gaattggcag aattctcagg cgttccagta tggaacggtc taactgacga
    14041 atggcaccca actcaaatgc tcgctgacta cttgactgtt caagaaaact tcggtcgctt
    14101 ggaaggcttg acattggtat actgtggtga tggacgtaac aacgttgcca acagcttgct
    14161 cgtaacaggt gctatccttg gtgtcaatgt tcacatcttc tcaccaaaag aactcttccc
    14221 agaaaaagaa atcgttgaat tggcagaagg atttgctaaa gaaagtggcg cacatgttct
    14281 catcactgaa gatgctgatg aagcagttaa agatgcagac gttctttaca cagacgtttg
    14341 ggtatcaatg ggtgaagaag acaaattcgc agaacgtgta gctcttctta aaccttacca
    14401 agtcaatatg gacttagtta aaaaagcagg caatgaaaac ttgatcttcc tacactgctt
    14461 gccagcattc cacgatactc acactgttta tggtaaagac gttgctgaaa aatttggtgt
    14521 agaagaaatg gaagtaacag acgaagtctt ccgcagcaag tacgctcgcc acttcgatca
    14581 agcagaaaac cgtatgcaca ctatcaaagc tgttatggct gctacacttg gtaaccttta
    14641 tattcctaaa gtataatttt agataataaa ccgtctacca acagctatga gggctgcgac
    14701 taatagcttt agtccggtcc tcttttatgt aatggtaatc tattatttct tataaaatat
    14761 gtgaaaaatc attaaattga aatctaaacg cattctattg agtgtgataa aggagaattt
    14821 atggcaaatc gtaaaattgt agtagctttg ggaggaaatg cgattctttc ttctgaccca
    14881 tcagcaaagg ctcaacaaga agctttagtt gaaacagcta agcatcttgt aaaattgatt
    14941 aaaaatggag atgatttgat tatcactcac ggtaatggac ctcaagttgg gaatctcttg
    15001 ctccaacatt tggcatcaga ctctgaaaag aaccctgcct tcccactcga ctcacttgtc
    15061 gctatgacag aaggtagcat cggtttctgg ttgaaaaatg ctttgcaaaa tgctctcttg
    15121 gatgaaggca tcgaaaaaaa tgttgcctct gttgtaacgc aagttatcgt agataaaaat
    15181 gatccagctt ttgttaactt gagtaaacca atcggtcctt tctattcaga agaagaagca
    15241 aaagcagaag ccgaaaagag cggagcgact ttcaaggaag atgctggccg tggctggcgt
    15301 aaggtcgttg cctcaccaaa acctgttgac atcaaagaaa ttgaaaccat ccgtactctt
    15361 ttaaataatg gtcaagtcgt cgtagctgca ggtggtggcg gtattcccgt cgtcaaagaa
    15421 aacaatggac atttgactgg tgtcgaagcg gttattgata aagacttcgc ttcccaacgt
    15481 ttggcagaat tggttgatgc agacctcttc atcgttttga caggtgtaga ttatgtattt
    15541 gttaactaca acaagccaaa ccaggaaaaa ttggaacatg tgaatgttgc ccagctggaa
    15601 gaatatatca aacaagatca gtttgcacca ggtagcatgc ttccaaaagt agaagcagct
    15661 atcgcttttg tcaatggtcg tccagaagga aaagcagtta ttacttccct tgaaaatcta
    15721 ggcgccttga ttgaatctga aagcggaaca attattgaaa aaggataagt tgttttacta
    15781 ataagatgta ttctatttct agtatcttta tatcaaatta gaaattattc ttgaaaacat
    15841 gtacaatatt tcaaaagata ctagttttag actttaatat ggtaaaacaa atataaatag
    15901 aaagcgtttt cttgaatgtt tatttaagaa agtagttggt tttttacact ttgttagaca
    15961 tcaggaggaa aaacaaatga gtgaaaaagc taaaaaaggg tttaagatgc cttcatctta
    16021 caccgtatta ttgataatca ttgctattat ggccgtgcta acttggttta tccctgcggg
    16081 ggcctttata gaaggtattt acgaggctca gcctcaaaat ccacaaggga tttgggatgt
    16141 cctcatggca ccgattcggg ctatgctagg tactcatcca gaggaaggtt cgctcattaa
    16201 agaaacgagc gcagcgattg atgtagcctt cttcatcctt atggttggtg gtttccttgg
    16261 cattgtcaac aaaactggtg ctcttgacgt agggattgcc tctatcgtga agaagtataa
    16321 gggccgcgaa aaaatgttaa ttttggtatt gatgcctttg tttgccctcg gtggtacaac
    16381 ttatggtatg ggtgaagaaa caatggcctt ctatccactc cttgtgccag ttatgatggc
    16441 cgttggtttt gatagcctga ctggtgttgc aattattttg ctcggttctc aaatcggctg
    16501 tttggcatct actctgaatc catttgcgac aggtattgct tcagcgactg cgggagttgg
    16561 tacaggggac ggtatcgtac ttcgtctgat cttctgggtt accttgactg ctcttagtac
    16621 ttggtttgtt taccgttatg cggataagat tcaaaaagat ccgactaagt cactggttta
    16681 tagtactcgc aaagaagatt tgaaacactt taacgtagaa gaatcttcat ctgtagaatc
    16741 tacacttagc agcaaacaaa aatcagttct cttcttattt gtgttgacat tcatcttgat
    16801 ggtattgagc ttcattccat ggacagacct tggcgttacc atttttgatg actttaatac
    16861 ttggttgact ggtcttccag ttattggtaa tattgtcggt tcatctactt ctgcactagg
    16921 tacttggtac ttcccagaag gcgcaatgct ctttgccttt atgggtatcc tgattggtgt
    16981 tatttatggt cttaaagaag ataagattat ctcttccttc atgaatggtg ctgctgactt
    17041 gctcagtgtt gccttgatcg tagcgattgc tcgtggtatt caagttatca tgaacgacgg
    17101 tatgattacc gatacaatcc tcaactgggg taaagaaggc ttgagcggtc tatcttcaca
    17161 agtctttatc gttgtaactt atatcttcta tctacctatg tcattcttga tcccatcttc
    17221 atctggtctt gccagcgcaa ctatgggtat catggctcca cttggagaat ttgtaaatgt
    17281 ccgtcctagc ttgattatca ctgcttacca atctgcttca ggtgtcttga acttgattgc
    17341 accaacatct ggtattgtga tgggagctct tgcacttgga cgtatcaaca ttggtacttg
    17401 gtggaaattc atgggcaaac tcgtagtcgc tattattgta gtgaccatcg cccttcttct
    17461 ccttggaacc ttccttccat tcctataaaa tagtgagtga ggtgattcca tgaaaataga
    17521 tataacaaat caagttaaag atgaatttct tatatcatta aaaaccttga tttcctatcc
    17581 ttcagtactc aatgaaggag aaaatggaac accttttgga caagcaatcc aagatgtcct
    17641 agaaaaaact ttagagattt gtcgagacat aggtttcact acctatcttg accctaaagg
    17701 ttattacgga tatgcagaaa tcggtcaggg agcagagctt ctggccattc tctgtcattt
    17761 ggatgttgtt ccatcaggtg atgaagcaga ttggcagaca ccgccatttg aagcaactat
    17821 caaagacggc tgggtattcg gacgtggtgt ccaagatgat aaaggccctt cgctcgcagc
    17881 tctctatgca gtaaaaagct tgctggacca aggtattcag ttcaaaaagc gcgtacgctt
    17941 tatctttggt accgatgagg aaaccctctg gcgctgcatg gcacgctaca ataccatcga
    18001 agaacaggcc agtatgggct ttgcacctga ctcatctttt cctctgacct atgctgaaaa
    18061 agggcttcta caggtcaaac ttcatggccc tggatcggat caactagagc ttgaagtagg
    18121 aggcgccttt aacgttgtac cagacaaggc caactaccaa ggtcccctct atgaacaggt
    18181 ttgtaacggt ctcaaagaag ctggttatga ttaccaatcc actgaacaaa ccgtaacggt
    18241 tctcggagtg ccaaagcatg ctaaggatgc tagtcaaggt atcaatgctg tcatccgact
    18301 agctaccatt cttgctcctc tccaagaaca ccctgctctc agttttcttg caacacaagc
    18361 aggtcaagac ggcacaggaa gacaaatctt tggtgatata gcagatgaac cttctggtca
    18421 cctatccttt aatgtcgcag gtctcatgat caatcatgaa cgttctgaaa tccgtattga
    18481 cattcggact cctgtcttag ctgacaagga agaactagta gagttgctta caagatgtgc
    18541 acaaaactac caactccgct acgaagagtt tgactatcta gcgcctctat acgtcgcaga
    18601 agacagtaaa ctcgttagca cactgatgca aatctaccaa gaaaagactg gcgataacag
    18661 tcctgctatt tcatccggtg gtgccacttt tgctcgcacc atgccaaatt gtgtagcctt
    18721 cggcgcctta ttcccaggag cgaagcagac agaacatcag gcaaatgaat gtgccgttct
    18781 agaagatttg taccgtgcta tggatattta tgccgaagcc gtctatcgac ttgcaactta
    18841 atcaggcaac tgtttctacc aaaaaaaatc gaccgattaa tgaactgcac cccaaaagtt
    18901 agacagaata aatctaactt ttggggtgtt ttattatgaa attgagttat gaagataaag
    18961 ttcagatcta tgaactaaga aagcaaggac aaagcttcaa acagctttca aaaagatttg
    19021 gtgtggatgt ttctggtcta aagtcatctg aatctttgag atgagcttta taaatcgctt
    19081 ttttcagttt ttgcactggt gtttcgataa actcaaactt tttagccgtg gtattgcctg
    19141 attttatagt atattgaaac tagaatagta cacctctact tctaaaacat ttttagaaat
    19201 cgatttgact gtcctgaacg atttgtcctg ttcttatttc attttactat atttgagcca
    19261 cttcgtcttt aacggcttta ttcataagct cttgtaattt ttctttacta tcaattactt
    19321 ctgattttcc gttgtaattt attgtaatag gttttaactt acctaatttc tcgacacgct
    19381 cattaatttg atcttttttg aaggctgcat atgtttttcc taagattttt tcgaaaatat
    19441 atttatcaga tagcggtttg ccttcttctt cagcttggtt tttgtattga tttgaaacat
    19501 aaggaacaaa tccttcatag taacctaatg ctcccataag ttcaaaagct tgttttctaa
    19561 ttcaaaccat tgcaactcag atttcagctt ttcagataaa tcctgctcat ccaaataatg
    19621 acttgaaatt agtgctgaac tcgtttctgt atcctgtaca ggctgatcac ccataccagc
    19681 aaaaaataaa ctcgttccta gcaagaccga acaagctcct attgcatatt tcctcaaaga
    19741 aaaacgctgc tttctctcaa attgaaattc tttcatccca tctcccatca ttcattatta
    19801 ctgtatattt tgtatatcag aaatagtttg tattcacaaa tctttctagt tattccctta
    19861 tcattcctaa ttaagggagg taacatacaa taatttttag ttaaatgtat atctatgttt
    19921 tttgtttttc ttaataaacg caatacaaaa agagcctgtt gccaagctct ttgtactcaa
    19981 tgaaaatcaa atagcaaact aggaaactag ccacaggttg ctcaaaacac cgttttgagg
    20041 tagtagataa gactgacgaa gtcagctcaa aacactgttt tgaggttgca gatagaactg
    20101 acaaagtcag taacatctat acggcaaggc gacgctgacg tggtttgaag agattttcga
    20161 agagtattag tctattattt cttctcagcg cgaagggctg acaagatttg tgttcggata
    20221 tcatccacac catttggcgt atttggtaaa aagatggttt gatttccttt agaggcaaag
    20281 gtattcaagg tatccaaata ctggttggtc aagaggatag acatgatttg ttcttctgtc
    20341 atgccaacat tggcttcctt gagttcggtg atagactctg ccaatccatc cacaatcgcc
    20401 ttacgttgtt gggcaatccc cacaccatga aggcggtctt tttctgcttc tgcttcagct
    20461 gcagtgacaa ttttaatctt gtcagcttcc gccaattctt gtgctgcgac ccgcttacgt
    20521 tgcgccgcat tgatttcatt catggattgc ttaacttctg catccggttc gactttggta
    20581 atcaaggttt tcacgataat gtagccgtaa gtggtcattt cttctgctac ttggtgttga
    20641 acttcaaggg caatctcatc ttttttctca aacaattcat ccaaggttaa ttttggaaca
    20701 gaagagcgaa gagcatcttc gatataagat ttaatctgag attctggacg tatgagttta
    20761 tagtaagcat ctgtcacgct ctgctcgttg acacggtact gagtcgctac attcatcata
    20821 acgaacacat tgtccttggt cttagtctca accacaatat cactttgcaa caagcgcaac
    20881 tgaatccgtg ctgcaatcga gtcaatccca aaaggcaagc gaatatgaat accgctatta
    20941 gcaacctttt ggtatttccc aaagcgttca ataatcgcca ccgactgctg acgaaccaca
    21001 taaactgtac tcagtgtgac tatcaccaat aggagcacac aaacaatcag aaaaatcatg
    21061 aaaaatattg ccataatgga acctccacaa gtatttttct agtattatag cacatttaaa
    21121 gaaggctgtg ccgtttttac tgcgattttt cctgaaatgt caataattag aggtgaattg
    21181 tcctattgtc gtccaatctc ttgctaaaat aactctttat aaaaggcaat cgtttcttct
    21241 aaggttggca taaatggatt tcctggtgcg caggcatcaa tcaaggcatt cttagaaagg
    21301 tattcaaagt cgaaatcttt ttcttcaata ccaagttcag tcagtttctt aggaatacct
    21361 actgtctcag aaagcttctc aatctcaaca atcgcataat cggcacattc ttgatctgat
    21421 ttaccttcta catgaagtcc caaggctttg gcaacattgc ggaaagcttc tggtacacgt
    21481 ttagcatttt catgttctat aactggtagc aacatggcac agcaaacacc atgtggcaaa
    21541 ttatatactg caccgagttg gtgagccatt gagtgaacat aaccaagacc agcattatta
    21601 aagctcatac caccaaggaa gatggcattg accatacctt cacgcgcttc aatatcatgt
    21661 ccattttcta cagcacgagg aagatattcc ttgataagct caatagcacc aatagacagt
    21721 ttcttggtta catcataagc accaggtgtt accaaagctt caacagcgtg agtcagagca
    21781 tccataccag tagcagcagt caaggcttga ggtttggaaa gcatgagttc agggtcattg
    21841 acagaaatca aggcaaggct attcttgtca accattacca tcttaacctt gcgttcttca
    21901 tcagtaatca catagttaat agtgatttct gctgatgtac ctgccgttgt attgatagcc
    21961 acaaccggca agcctttttt agcagactta tgaagccctt cataatcctg tggttttcca
    22021 ccatttgtag ccatgataga aatacaacta gctgcatcct gtggagaacc cccgccaaga
    22081 ctgatgataa aatcacatct atgttcttgc aaagcagcta ccccatctgt gacattttta
    22141 caagtagggt ttggctctac atcgctaaag atgacatatt cgattccttc tgtatccagt
    22201 ggttttaaag tcttaggtaa aatatcactg ccttcgatgt acttatctgt caccaaaagt
    22261 gcctttttat agccaagttc cttgatataa ggacccactt catttacaac accttttcca
    22321 ataaggttga ctgccggaac ataaaatata gccatataat tttcctcctg cgcctccgcg
    22381 ctatctattt aacatcatta tattactttt tgtattcgtt ttcaattatt tgtgaattgt
    22441 ttaacaaatc tttttaaaag gataggaggg acgtaagttc acctcctata taaacaagtt
    22501 ttatttatgt agtggtccca acaactgaca tgcacgatag tctgctgatt ctagatcttc
    22561 tgttccaaat aaggaccaat ttttaggtct aaagatatct tcctcaggta cattatgcat
    22621 attgacagga attctcaaca tagaagccaa ggtaatcaag tctgctccaa tgtgtccata
    22681 tgttatggct ccgtgattag ctccccaatt attcatgacg tcatagacag acttgaaagc
    22741 accttttcct gtcaaacgtg gagcaaacca agtagttggc catcctgaat ctgtacgatt
    22801 atctaaagta tggtgaacat cttcaggaag ttcaagtgtg taaccttctg caatttgtag
    22861 cactggacca acccctttta gaagattgag acgtaccatt gttactggca tatccccctt
    22921 cgtcaagaaa cgagttgaga atcctcctcc acggaagtac tcgcggtttg ctggtgggaa
    22981 gtctgtattt tcaagcatag cctgtacttc actttcttcc aactcccaga atggtttcat
    23041 aacaggtttg ccatctcgag tagcttgacc tgtaccatcc aatgtacaag aaccagagtt
    23101 gattagatgt aagaagccag ctgcagcaca accctctaaa gtatgtcccg ttacacgttt
    23161 aacagcctct ggactccaat aagtgcgcac atcagcaaag atttgtggag tatttgttaa
    23221 tagataatta aagagcatag acacaccatt tagtgaatca ttctctgtcg caaatacaaa
    23281 tggttttcga ataccattcc agtcaaactg agtattgagg aaagtttcca taaaatctcc
    23341 atttggaaaa tggtctgtcc actgacgttg accttggaaa ccagctacta aagcatggtg
    23401 accaaccgct tcttcctcaa aaccaagttc agcaagcctt gggttaccaa ccattaagtc
    23461 acgtccaatc atgaacatct taataacaaa ttcccattgt ttttctttct cttctttaga
    23521 aagaatcaaa tcctcacgat ttcggtcaac cccttctttg atatgttctt ttacccaaac
    23581 catagcacgt tcgaactctt ctgggtcata aataccacgg tccatacggc gcgtgaactc
    23641 cgtcatatct accgattcat ttcgcattcc taagtattct tggaagaaat ctggatttac
    23701 aatagaaccg ccaatcccca tcgaaacact acccattgat aggtaagcag tgtctctcat
    23761 caagccagtt gcaagagctg cacgcgcata acgtaaaagt ttttctttga catcttctgg
    23821 aatatctgta tcattagctt cctgaacatc tctaccataa atcccaaagg ctggaatccc
    23881 tttttgagca tgtgaagcta gtacagctgc aagatagaca gctcctgggc gttctgtccc
    23941 attaaatccc caaatagcat gaggaatatc tggagacata tccatagttt cactaccata
    24001 acaccagcat ggtgtaactg taattgttgc gcaaacattt gattttttaa acaactcatg
    24061 ggaagctgca gcctctggaa cacgaccaat ggtagatgga gaaatcacac attccacagg
    24121 ttccccatct ggatatttca atgtgcttga aatcaaatct gccacacttt tagccatgtt
    24181 cattgtttgt acttcaagtg attcgcgtac accttgacga cgaccatcaa tagtcggacg
    24241 aatcccaata cgtggatgtt gaatcatact attttcctct tatttttctg tttctttcat
    24301 actaccgatg ataattttta aaattactta taagtataaa cctctacctc tgccaaactt
    24361 aaaggaattc ctgcgtttct caaagaaatt ctaacctttt ttcccttcag cccttttaag
    24421 tctatggata gattattgct ttctaaactg tcaatatgtt gtttaaaaac ttcatgatta
    24481 tttgaatcat atataataat atcaaaattt gataatctct gaatttcagc atctgttcta
    24541 ttataaataa ttaacttttc taattcttcg gtttgtgcta aatctatctc ccaccatgaa
    24601 ggagaatctc ctttggtatg agtcactgaa tgatgaccat aatctccgtt tttatttcca
    24661 tcaactgcta gacgagaaaa accattgtaa tccgttgaac tctgtcgagt ttctttggtt
    24721 aatgcaatat tagaaagttt cttcggagtt ctctttgaac cataggcttc aacttccgct
    24781 aaacttaacg gaatagctgc tgattttaat tctattttga ctagcttagc ccctacagaa
    24841 ggtactttta aagataacaa accatcaact actttatcaa aatgtcttct aaaaacttct
    24901 tctcctgatg aagatagaaa aataacatca aaattagata aacgctgagg ttcggcatct
    24961 gttctattat aaatatcaac tttagaaacc gtaaactctt ctcccagatc gacctgccac
    25021 caagcgttag aatctgcctt agtatgagtc accgaatgat gtccgtaatc tccatcttta
    25081 ttaccatcaa ctgctaaagc agctacaccc tcataattgg ttgaactttg agtagctacc
    25141 ttatttgtag agactacttt atcttctgtt attttatcta tatcctcttc agattgctta
    25201 ccatctgatt ctctaaaaac ctctacttct gctaaactca aaggcactcc actcgttagt
    25261 aatttaactt taatatacct tgctcctttt tctttgaaat ctagactaac agattcaccc
    25321 gacaaattat taacatgttt cttagcaact tcgtttctat tattgtcata tagaatcaca
    25381 tcaaaattag atagacgttg agtctcagca tctgtgcgat tataaatttt aacaagccca
    25441 actttatcca tttttttcaa atcgacttcc caccaagagg gattatctgc cctagtgtgt
    25501 gttaccgaac cagagttaaa attaccattt ctgttaccat ccacagctct attagggtct
    25561 ccattgtaat ctacagaact ttgtgttgtt ggttttgcat atgctatatt caaattacca
    25621 tcattaaatt tatctggtgt tgggaaaggg actgggcctg tcccttcagt atttatagac
    25681 atctctacca ttccattatg attaaccgta atggtataaa catgggtatt ctcatcccaa
    25741 ttttctgtat aagtataatg atttttatcg ccacttatat ttatctgagg tttatgacca
    25801 gtatgccctt ttaatgtaag tgttgttgtc ctaaagtcat tatctacagg attgatggaa
    25861 taatttttgc ttatccagtt cgctaactct aattcttctt tcttccaact ttttgatgca
    25921 tcaaaatttc ctgataatgc ccacatagct gtcttatctg tcctgtaatt
//
LOCUS       DAVBEM010000031        24327 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVBEM010000031 DAVBEM010000000
VERSION     DAVBEM010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24327
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.031"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(<1..618)
                     /locus_tag="VQ548_001288"
     CDS             complement(<1..618)
                     /locus_tag="VQ548_001288"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HET2654134.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEK"
     gene            complement(769..2079)
                     /gene="secY"
                     /locus_tag="VQ548_001289"
     CDS             complement(769..2079)
                     /gene="secY"
                     /locus_tag="VQ548_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HET2654135.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            complement(2092..2532)
                     /gene="rplO"
                     /locus_tag="VQ548_001290"
     CDS             complement(2092..2532)
                     /gene="rplO"
                     /locus_tag="VQ548_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HET2654136.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            complement(2677..2901)
                     /gene="rpmD"
                     /locus_tag="VQ548_001291"
     CDS             complement(2677..2901)
                     /gene="rpmD"
                     /locus_tag="VQ548_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HET2654137.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            complement(2873..3367)
                     /gene="rpsE"
                     /locus_tag="VQ548_001292"
     CDS             complement(2873..3367)
                     /gene="rpsE"
                     /locus_tag="VQ548_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HET2654138.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            complement(3385..3741)
                     /gene="rplR"
                     /locus_tag="VQ548_001293"
     CDS             complement(3385..3741)
                     /gene="rplR"
                     /locus_tag="VQ548_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HET2654139.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(3825..4361)
                     /gene="rplF"
                     /locus_tag="VQ548_001294"
     CDS             complement(3825..4361)
                     /gene="rplF"
                     /locus_tag="VQ548_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HET2654140.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            complement(4553..4951)
                     /gene="rpsH"
                     /locus_tag="VQ548_001295"
     CDS             complement(4553..4951)
                     /gene="rpsH"
                     /locus_tag="VQ548_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HET2654141.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(5236..5505)
                     /gene="rpsN"
                     /locus_tag="VQ548_001296"
     CDS             complement(5236..5505)
                     /gene="rpsN"
                     /locus_tag="VQ548_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HET2654142.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            complement(5523..6065)
                     /gene="rplE"
                     /locus_tag="VQ548_001297"
     CDS             complement(5523..6065)
                     /gene="rplE"
                     /locus_tag="VQ548_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HET2654143.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            complement(6089..6394)
                     /gene="rplX"
                     /locus_tag="VQ548_001298"
     CDS             complement(6089..6394)
                     /gene="rplX"
                     /locus_tag="VQ548_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HET2654144.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            complement(6472..6840)
                     /gene="rplN"
                     /locus_tag="VQ548_001299"
     CDS             complement(6472..6840)
                     /gene="rplN"
                     /locus_tag="VQ548_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HET2654145.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            complement(6866..7126)
                     /gene="rpsQ"
                     /locus_tag="VQ548_001300"
     CDS             complement(6866..7126)
                     /gene="rpsQ"
                     /locus_tag="VQ548_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HET2654146.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            complement(7151..7357)
                     /locus_tag="VQ548_001301"
     CDS             complement(7151..7357)
                     /locus_tag="VQ548_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HET2654147.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            complement(7367..7780)
                     /gene="rplP"
                     /locus_tag="VQ548_001302"
     CDS             complement(7367..7780)
                     /gene="rplP"
                     /locus_tag="VQ548_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HET2654148.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(7784..8437)
                     /gene="rpsC"
                     /locus_tag="VQ548_001303"
     CDS             complement(7784..8437)
                     /gene="rpsC"
                     /locus_tag="VQ548_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HET2654149.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(8450..8794)
                     /gene="rplV"
                     /locus_tag="VQ548_001304"
     CDS             complement(8450..8794)
                     /gene="rplV"
                     /locus_tag="VQ548_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HET2654150.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            complement(8806..9087)
                     /gene="rpsS"
                     /locus_tag="VQ548_001305"
     CDS             complement(8806..9087)
                     /gene="rpsS"
                     /locus_tag="VQ548_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HET2654151.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            complement(9191..10024)
                     /gene="rplB"
                     /locus_tag="VQ548_001306"
     CDS             complement(9191..10024)
                     /gene="rplB"
                     /locus_tag="VQ548_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HET2654152.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(10042..10338)
                     /locus_tag="VQ548_001307"
     CDS             complement(10042..10338)
                     /locus_tag="VQ548_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HET2654153.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(10338..10961)
                     /gene="rplD"
                     /locus_tag="VQ548_001308"
     CDS             complement(10338..10961)
                     /gene="rplD"
                     /locus_tag="VQ548_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HET2654154.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            complement(10986..11612)
                     /gene="rplC"
                     /locus_tag="VQ548_001309"
     CDS             complement(10986..11612)
                     /gene="rplC"
                     /locus_tag="VQ548_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HET2654155.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            complement(11828..12136)
                     /gene="rpsJ"
                     /locus_tag="VQ548_001310"
     CDS             complement(11828..12136)
                     /gene="rpsJ"
                     /locus_tag="VQ548_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HET2654156.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(12402..13019)
                     /locus_tag="VQ548_001311"
     CDS             complement(12402..13019)
                     /locus_tag="VQ548_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HET2654157.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            complement(13016..13606)
                     /gene="nrdG"
                     /locus_tag="VQ548_001312"
     CDS             complement(13016..13606)
                     /gene="nrdG"
                     /locus_tag="VQ548_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HET2654158.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKEIYEQVKRE"
     gene            complement(13599..14105)
                     /locus_tag="VQ548_001313"
     CDS             complement(13599..14105)
                     /locus_tag="VQ548_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2654159.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDVEDFSYEEWL
                     EGNRNKEMGIWLPENRVPSIQFVLFGESGCALGFLNLRLRLNEGLLNYAGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            complement(14149..14289)
                     /locus_tag="VQ548_001314"
     CDS             complement(14149..14289)
                     /locus_tag="VQ548_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654160.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            complement(14301..16508)
                     /gene="nrdD"
                     /locus_tag="VQ548_001315"
     CDS             complement(14301..16508)
                     /gene="nrdD"
                     /locus_tag="VQ548_001315"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HET2654161.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNCRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            complement(16628..18166)
                     /locus_tag="VQ548_001316"
     CDS             complement(16628..18166)
                     /locus_tag="VQ548_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET2654162.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            complement(18203..18346)
                     /locus_tag="VQ548_001317"
     CDS             complement(18203..18346)
                     /locus_tag="VQ548_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654163.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            complement(18424..19956)
                     /gene="cls"
                     /locus_tag="VQ548_001318"
     CDS             complement(18424..19956)
                     /gene="cls"
                     /locus_tag="VQ548_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HET2654164.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            complement(20102..20659)
                     /locus_tag="VQ548_001319"
     CDS             complement(20102..20659)
                     /locus_tag="VQ548_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HET2654165.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQPAQQNTNTANAGGNQNQAAPVQNQPVAQP
                     TDIDGTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKI
                     YTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            complement(20656..21906)
                     /locus_tag="VQ548_001320"
     CDS             complement(20656..21906)
                     /locus_tag="VQ548_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET2654166.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRIQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFEMLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNFSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSCREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            complement(22114..22419)
                     /locus_tag="VQ548_001321"
     CDS             complement(22114..22419)
                     /locus_tag="VQ548_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HET2654167.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            complement(22435..22854)
                     /gene="ruvX"
                     /locus_tag="VQ548_001322"
     CDS             complement(22435..22854)
                     /gene="ruvX"
                     /locus_tag="VQ548_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HET2654168.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPLDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            complement(22858..23124)
                     /locus_tag="VQ548_001323"
     CDS             complement(22858..23124)
                     /locus_tag="VQ548_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HET2654169.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            complement(23211..23780)
                     /locus_tag="VQ548_001324"
     CDS             complement(23211..23780)
                     /locus_tag="VQ548_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET2654170.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            complement(23846..24244)
                     /gene="spx"
                     /locus_tag="VQ548_001325"
     CDS             complement(23846..24244)
                     /gene="spx"
                     /locus_tag="VQ548_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HET2654171.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
BASE COUNT         6740 a         5398 c         4560 g         7629 t
ORIGIN      
        1 tttttcaata tctgagaaga catcattgat atcttgatta ccttcgatgt catgaaccaa
       61 acctttggca cggtagtgag caatgattgg ttctccttga gcaatattaa catccaaacg
      121 acgttttact gtctcaggct tatcatcttc acgttggtag taatcttctt ctttatagtc
      181 aactggtggg ttaaagacct tgtggaaagt ttctccagtt acgcggtgga tgatacggcc
      241 actcaaacgt tccaagaggc tgtcagggtt cacttcaata ttgataatac cttctagttc
      301 aatgccaagt tcagccaatg ttttgtccaa ggcatgagct tgttcaattg tacgtgggta
      361 accatccaat aagaatcctg tttctttaat atcatcttgt gaaaggcgtt cttttacgat
      421 tccatttgta acttcgtcag gaaccaattc acccttgtca atatatgact tagcaagaac
      481 acccatttca gtttgatttg ccattgcagc gcggaacata tcacctgttg agatatgtgc
      541 aacatggaat tgttctacga tttttgctgc ttgagttccc ttacctgcac caggtaagcc
      601 cataatcaaa agattcatga tttgatctcc ttattttatt tttaaataga agcaaaaagt
      661 cttttcaccc ctatttaaaa acaaaataga agaggggaga tccaactctt acaaatgtca
      721 gagtttaaac ctccactccc tcagtattta ctgattcagt aaatactttt attctgttct
      781 gtccatgaaa ccaacatact tacgtttcaa taggtaacct tccaattgct tgattccttc
      841 gatacctgta gagataatga tcaagagact tgttccacca aaggcaacaa catcagaaag
      901 accaaataca tctttagctg caatcggtaa aatggaaatc acaccaagga agagggaacc
      961 aacagttgca agacgacgaa gaagtttaga catatattct tctgtacctt taccaggacg
     1021 aactccatgg atataggcac cactcttttg taggctctct gctgcttttt caggattaat
     1081 ctgtacaaac gtatagaaga atgtaaagag aataatcaac aaagcataca tggcaatacc
     1141 agttggagaa gtagttgcca acatctcttg tgctaccctt acccaagccc aatcatgacc
     1201 tgtggcactc aaaaactgaa gaatagccgc aggcgctgca gtaatcgaac tggcaaagat
     1261 aacagggata actccagcag ggtttacctt taacggaagg taagagctag atggagcacc
     1321 ttgtgcaacc ttagtatatt ggattggaat tttgtattct gcttgttgaa cataagttgt
     1381 aaagtaaata atcaacaata cagtaataat caaaatgatt acgaaaatga tagatgaagt
     1441 gatacggcta cttgggacgt tcacaaagta gtccacatag atgccctgaa tcatctctgg
     1501 aattgaggaa acaatcccgg caaagataat catggaaaca ccgtttccgt atcccttatc
     1561 tgtaatttgc tcacccaacc aagtgacaat catactacca gctgttaaga tgataccaat
     1621 cgtcagaaaa acttgtggag ttaaagcagt tttaatcaat tgagctccag ccaaggtatt
     1681 aaaaccagct gtaatcccga tagattgcac aaaagcgaga actagagcaa tataacgagt
     1741 agcttgattc aattttcttc gacctacttc cccttgttta ccccactcta caaacttggg
     1801 taaaatatcc atttgcaaga gttggacaac aatagaagcg gtgatatagg gactaactcc
     1861 tagggcaaaa atcgaaaagt tttttagggc attccccgac accaagctca acatgtttaa
     1921 gaaggataat ccacttaaag cattcaagct attggcattc acaccaggaa ctgtaatgct
     1981 agttccgata cgaaagacca aaacgataaa aattgtaaat aaaatttttg atcgaacctg
     2041 cttgacttta agagcttctc ttaataattt aaaaaacata ggtcacctct cttagatgac
     2101 ttctactgaa ccacctttag cagtgatagc ttcttcagct gatttagaga atttagctgc
     2161 tttcacagtc aatttcttag tcaactcacc gttaccaaga attttaatac ctgacttttc
     2221 agctttaaca attcctgctt cgataagaac aactggagtt acttcagcac catcttcaaa
     2281 gacgttcaat tggtcaaggt tcacaattgc gtattcttta gcgttgatgt tagtgaatcc
     2341 acgttttgga agacgacgga acaatggagt ttgtccacct tcaaaaccaa ggcgaactcc
     2401 gccaccgcta cgagcttttt gacctttttg accacgacca gatgttttac cgttacctga
     2461 tgaagtacca cgaccaacgc ggttacgtac tttacgagaa ccttctgcag gtttcaattc
     2521 atgaagtttc atttttattt tctcctcttt tgtaaaatgc tagcgccgat aagggagaaa
     2581 aggttgtctc ccccatcaac tcgcctatac gatgtcatca tagatgacta tatctagttt
     2641 taggggatgg tacagtgcac atcccctaaa acttcattag tttacttctt caactgttac
     2701 taagtgagat actgctgtaa tcataccacg gatagcagcg ttatcttctt taataacaga
     2761 gctgttcaat ttgccaagtc caagtgctac aacagtttta cgttgtgatg gaatgcgtcc
     2821 gattggagac ttagtcaaag taattttaat ttgagccatt ttatcccctt tcttatgcca
     2881 aatcagaaac tgaaatacca cgaagggcag caatttcttc agcgcgtttc aattgtttca
     2941 aaccttcaac agttgcacga acaatgttga ttggagtgtt agaaccaagt gatttagatg
     3001 taatatctgc cacacctgcc aattccacaa cggcacgaac tgcaccacca gcggcaactc
     3061 cagaaccttc tacagcaggt ttcaacaata ctttagctcc accgaattct gaaagaactt
     3121 cgtgtgggat tgttgttcca accataggaa cttcgatcaa gtttttctta gcatcatcta
     3181 ctgctttacg gattgcttct ggaacttctt gagctttacc agtaccaaat cctacgcgac
     3241 cattgtggtc accaacaaca acaagagctg cgaaacgaag acgacgtcca cctttaacaa
     3301 cttttgtaac acggttgaca gcaactacgc gttcttctaa ttcaactgca ttgtctttaa
     3361 atgccatttt ctagtgtcct cctattagaa tttcaatccg ttttcacgag ctgcatcagc
     3421 caaagctttc acacgtccgt gatatagata tccaccgcgg tcgaacacca cttctgaaat
     3481 acctttagcg tttgcacgtt ctgcaacgag tttaccgaca gcaacggctt gttcagtttt
     3541 agttcctttt gaaacttctt tatcaagagt tgaagcactt gcgagcgtta cacccgctac
     3601 gtcatcaatc acttgagcgt agatgcctgt attagaacgg aatacgttca aacgtgggcg
     3661 atcagcagtt ccagagagtt ttccgcgaac gcgacggtgg cgtttttggc ggagtttgtt
     3721 tttatctggt tttgaaatca cagttttcac ctctttagtt ttaaatcgtg tgctatgcac
     3781 aaagttggaa aataggttgg tggttgatga tcaaccactc aacattattt acctgtttta
     3841 ccttctttac ggcgaacgaa ttcaccaacg taacggatac ctttaccttt atatggttct
     3901 ggtgaacgaa ggctacgtac gtaagcagct gtttgaccaa ctacttcttt tgaaattccg
     3961 ctaacaacga ttgttgttgg gtttggaagt tcaaaagtaa ttccttctgg agcttcaact
     4021 tcgtctggat gagatttacc aacagccaaa acaagtttag atccttgaag ctgtgcacgg
     4081 taaccaaccc cacgcatttc aagttctttc ttgaatcctt ctgatacacc aacaaccatg
     4141 ttgttcaaaa gggcacgagt agttccgtgg atagttttca tttcttttga atcgtttgga
     4201 cggtgaagag ttatttcagt accttccaca cggatttcaa tatcttttga gaactcacga
     4261 gtaagttctc ctttaggtcc ttttacagtt acaacgttgt cattgttagc gagttcaaca
     4321 ccagcaggca acacgataac tttattacca atacgtgaca tgtttatttt ctcctgttaa
     4381 attgtcaggc cagaacggcc agttttcacg gggttcagat acttatttag ttcaagagct
     4441 gaactgaaca cgctctaaga actgtgcaaa atagataagt tggcttgttt gtaaacaaac
     4501 ttctccaact tcctaatttt gctttgttct ttacgagctt tgtatcttga ttttaccaaa
     4561 cgtaagcgat aacctcacca ccaacattct tttggcgtgc ttctttatca gtaagcaaac
     4621 cttcagaagt tgaaaggatg gcaattccaa gtccgttaag aacttttgga aggtcttcac
     4681 gttttttgta gacacgaagt cctggtttag aaacacgttt caagttagtg ataactttct
     4741 caccatttgg tccgtattta agaaatacac ggatgacgcc ttgtttgtca tcttcaatga
     4801 tttcaacgtt ttttacaaaa ccttcgcgtt taaggatttc agcaatccct tttttgatgt
     4861 ttgatgcagg tacttcaagt acttcgtgtt tagcttggtt agcattacga atacgagtta
     4921 ggaagtctgc gattgggtca gtcataacca ttttgttttt ctcctcttac tagtagtttg
     4981 caagttgcac ttgctagtta atacatgata caaagagcgt aacagcacga gcaaaaatag
     5041 acaatttaat gcagaagcaa tgctccaaag caaattggtc ttttttgcca aagctgtagc
     5101 tcgtgttcaa attggcaagc ccaattgaac ccgggctaaa ctctgtgtga aaaagataaa
     5161 ctttcctaga aactttagtt tcttcgtcaa gtttcctatt tttacttgga gttttgacgc
     5221 tcttgatatc ttaaattacc aagatgcttt tgttacacca ggaatttgac ctttatgcgc
     5281 aagttcgcga aaagcgatac gactcagacc aaatttgcgg taaactgaat gtgggcgccc
     5341 cgtaactcta caacgattat gtaaacgagt cggtgaggcg ttgcgaggta atttagataa
     5401 accttcgtag tcccctgccg cctttaatgc agcacgtttt tcagcataac ggtcaacaat
     5461 tttttggcgt ttagcctctc tagctaccat tgatttttta gccattagat ttacctccta
     5521 tattattttg caaaaggcat tccaaggcct gtaagcaatg cacgtgactc ttcgtcagtg
     5581 ttagcagttg ttacgataac gatgtcaaga ccacgagttt tgtcaacgtc atcgaagttg
     5641 atttctggga agattaattg ttctttcaca ccaagtgtgt agttcccgcg tccatcaaat
     5701 gattttgttg gaacaccgtg gaagtcacgt acacgtggaa gtgaaactga taccaattta
     5761 tccaagaatt cgtacatacg ttcaccacga agggtaactt ttgcaccgat cgcaacacct
     5821 tcacgaagac ggaagccggc gattgatttt ttagctttag tgataagtgg tttttgacct
     5881 gagataagtg ccaattcttc agcagctttt tcaaggcttt tagcgtttga tacagcttca
     5941 ccaacaccca tgttcaaaac aatcttatct actttaggca cagccatcac tgatgagtag
     6001 ttgaattgtt ctgtcaaagc aggaactact tcattaagat atttttcttt taaacgattt
     6061 gccattatac ttctcctttc cttcgtgatt aatcaagcac ttcgcctgat tttttgttgt
     6121 agcgaacttt tttaccgtct acaaatttgt aaccaacacg accagctaca ccatttttgt
     6181 ccaaaacttg aacgtttgat acgtggatag ctgcttcttt ctcgatgata ccaccttgag
     6241 gaagctcgtt agttggacgt tggtgtttct taacaatgtt aacaccttca acgataactt
     6301 tgtttacttt tggaagggca gtaaggacaa cagcttctgt tcccttatct ttaccagcga
     6361 ttacgcgaac tttgtcgcct ttttttacaa acattaggtt tctccttgat ttttcttacg
     6421 cccataaggg caccctagct tgaagctagg ggactagttt gttcctaaaa attaaagtac
     6481 ttctggagca agtgacacga tcttcatgaa gccaccttca cgcaattcac gtgcaactgg
     6541 gccaaagata cgtgttccgc gaggagtttt gtcttcacgg atgataactg ctgcgttttc
     6601 gtcaaatttg atgtatgaac catcagcacg acgagcacct gatttagtac gaacgataac
     6661 tgctttaaca acgtcacctt ttttaaccgc accaccagga gtagcttgtt ttacagatgc
     6721 cacgataaca tcaccgatgt ttgcaaattt acgtcctgaa ccaccaagaa ctttgatagt
     6781 caagatttcg cgagcaccgc tgttgtctgc gactttcaaa cgagtttctg tttgaatcat
     6841 ttcagttttc tcctttcagg tttgattaga tgatgaccgc ttcttcaaca acttctacaa
     6901 gacggaaacg ttttgtagct gaaagcgggc gagtttccat gatacgtacg atatcgcctt
     6961 ctttggcaac attgttttca tcatgagctt tgtatttttt agagtagtta atacgtttac
     7021 catagactgg gtggttacgt tttgtttcaa ctacaactgt gattgtcttg tccattttgt
     7081 cagatacaac acgtccaaca agaactttac gattattgcg ttccattgaa atttctcctt
     7141 ccctagtcta ttatttcgct tcagattgaa ctgttttgat acgagcgatt tgttttttaa
     7201 cttctttcaa gcgagctgtt tgttccaatt gaccagtagc agcttggaaa cgaagttcaa
     7261 acaattcttt tttcaattcg ttttcgcgct tcgcgagttc ttcttgagaa agaccacgaa
     7321 gttctttaac aaattctttt acttcattaa gtttcatgcc ttctccttat tctgcttcac
     7381 gttttacgaa tttacattta actggcaatt tgtggctagc aagtcgaagc gcttcacgtg
     7441 caatctcttc agatacacca gcgatttcga acatcacttt accacgttta actggtgcta
     7501 cccaaccttc aggtgcccct ttaccagatc ccatacgcac accgatagct ttagcagtgt
     7561 atgatttgtg tgggaagatt ttaatccaaa ctttaccacc acgtttcatg taacgagtca
     7621 tggcgatacg agcagcttcg atttggcggt tagtgatcca gtggctagtt gtagcttgaa
     7681 gaccgtattc accgaatgct acttcttttc caccttttgc ttcaccgcgc atttttccac
     7741 ggaactcacg acggtgttta acacgtttag gtactaacat tggttattta cctcctttag
     7801 tgtttttacg agctggaaga acttcaccac ggtagatcca tactttaaca ccaagtttac
     7861 cgtatgtagt atctgcttct tcccaagcgt aatcgatatc tgcacgaagt gtgtgaagcg
     7921 gaacagttcc ttcagagtat ccttcagcac gggcgatatc tgcaccgttc aaacgacctg
     7981 atacttgagt tttgattcct ttagctccag cacgcattgc acgttggatt gcttgttttt
     8041 gtgcacgacg gaaagcaaca cgttgctcca attgacgagc aattccttca cctacaaggt
     8101 gagcatccaa atcaggttgt ttgatttcga tgatgttgat gtgtacttgt tttccagtca
     8161 atttgttaag ttttgcacgg agtgcatcaa cgttagcacc acctttaccg ataaccatac
     8221 ctggtttagc agtgtgaagt gaaacgttaa ctttgtttac tgcgcgttcg atttcaatag
     8281 ttgaaactgc tgcgtcagca agttcttttt gaacgaattt acggattgca agatcttcat
     8341 gaaggtaatc cgcgtattct ttttcagcat accatttggc atcccaatca cggatgatgc
     8401 cgacacgcat accaattgga tgtacttttt gacccacgat tttacctcct tatttttctg
     8461 caacagctac agtgatgtga gctgtacgtt tgttgattgg tgaagctgaa cctttcgcac
     8521 gtggacggaa acgtttcata gttggtcctt cgtttgcgaa tgcttcagat actaccaaat
     8581 tagctttatc caaaccaaag ttgttttcag cgttagctac agctgagttc aaaactttca
     8641 agatgatttc agcagctttg tttggagtga atgtcaagat tgcgattgca tcggctacgc
     8701 ttttaccacg gatgttatca agaacaagac gtgatttacg aggtgaaaca cgtactgtac
     8761 gagccattgc tttagctgaa gtaatttctg ccatttatgt tctccttatt ttctacgtgt
     8821 tttcttgtcg tctgcagcgt gacctttgta agtacgagtt ggtgcaaatt caccaagttt
     8881 gtggcctacc atgtcttctt ggatgtaaac aggtacgtgt ttacgtccgt cataaactgc
     8941 aatagtgtaa ccaatgaaac ttgggaagat cgttgaacga cgtgaccaag ttttaataac
     9001 ttttttcttt tcgtcgttag cttgagcttc aacttttttc atcaaatgct catcgacgaa
     9061 aggtcctttt ttaagactgc gtcccatttt tatattttct cctttaaatg ttgtaccaca
     9121 gcggcttgca ctcctatgga gcgctaccga gctggcggat ttactagttg cttaagcgac
     9181 tagtttaata ttatttctcg ttgcgacgac gaacgataag tttgtcagat ttcgctttct
     9241 tgttacgagt tttaagacca agagcaggtt tgccccatgg agtagatggt gctttacgac
     9301 caactggtgc tttaccttca ccaccaccgt gtgggtgatc gttagggttc attacagaac
     9361 cacgaactgt tgggcggata cctttccaac ggctacgtcc tgctttacca aggtttacaa
     9421 gtccatgttg ttcgtttccg acaacaccaa ctgtagcacg gcaagttcca agaatcatac
     9481 gaacttcacc tgattgaaga cgaacaagaa catatttacc ttcagaaccc aatacttgag
     9541 cagatgcacc agcagcacgt accaattcac caccacgacc tggtttcaac tcgatgttgt
     9601 gaatcaaagt accaactggg atgttagcaa gtggaagagc gtttccgact ttgatatctg
     9661 cttctggacc tgaaacgata cgttgaccta cttcaagacc ttttggagcg atgatgtatg
     9721 ctttcacacc gtcagtgtag tgtacaagag cgatgtttgc agaacggttt ggatcgtact
     9781 cgattgtttt aacaactgct tcaacgttgt ctttattacg tttgaagtca accaaacggt
     9841 aaaaacgttt gtgtccacca ccttggtgac gaactgtgat acgaccgttg ttgttacgac
     9901 cagccttgct cttcaatgca acaagcaatg atttttcagg agtgcttgtt gtgatttcag
     9961 cgaaatccaa agaagtcata ttacggcgac cgtttgttgt tggtttataa acacgaattc
    10021 ccacgatatt tcctccttag attattcagc ttcagcagca aacaactcga ttgctttaga
    10081 atcagctgta agtgtgatga tagctttttt agttttgtta gtaaaaccag tgtaacgtcc
    10141 aacacgttta gcttttggtt ttacgttgat tgtgttaaca ttggcaactt taacaccttc
    10201 gaaagcagct tcaacagctt gcttgatcaa aagtttgtgt gcacgagtgt caacttcaaa
    10261 tacatatttt cctgcttcaa gttgagccat tgagctttca gtgatgacag gttttttgat
    10321 aacatcatac aaattcatta tgcaagaacc tcctcgattt tagagatagc tgcttgtgtg
    10381 acaagaagtt tgtcgctatt tgcgatgtca agaacacttg cagttgtagc agttgcaact
    10441 ttcacgtttg gaaggttacg agctgaaaga gctgcgaatt catttccttc ttcaaggata
    10501 acaagaactt tagaatcgat gctcaatgct gcaagaactt ttgcaaattc agcagttttt
    10561 ggagctgtaa atgaaagagc gtctacagct acgaatttgt tttcagcaac tttttcagag
    10621 taaactgatt taagagctag gcgacgaact ttttgtggaa gtttgtagcc gtatgaacgt
    10681 ggagttggtc cgaagacaac accaccacca cgccattgtg gtgagcggat agaaccttga
    10741 cgagcacgtc cagttccttt ttgacgccat ggtttgcgtc caccacctga tactgcagag
    10801 cggtttttaa cagcgtgtgt tccttgacga aggcttgcgc gttggctgat gattacatca
    10861 aacacaactg attcatttgg ttcgatacca aatactgcat cgctaagaac aacttggcca
    10921 gcttctttac cagtttggtc aaataatgtt acgtttgcca ttgtgactga tttccccttt
    10981 ctttattatt taccagcttt aactgctgat ttgatagtga taagagattt cttagcacct
    11041 ggtacgttac ctttgataag gataacgttc ttttctggaa caacttgtac aacttcaagg
    11101 ttttgaattg ttacgcggtc gccacccata cgccctgcaa ggtttttacc tttgaatacg
    11161 cggttaggtg caacaggtcc catagaacct ggacgacggt ggtaacgaga accgtgagcc
    11221 attggtccac gtgattgtcc gtggcgtttg ataacacctt ggaaaccttt acctttagaa
    11281 gtaccagtta cgtcaacaac gtctccagct gcgaatgttt caactgtaat ttcagcacca
    11341 acttccaagc cttcaacgtt tttgaattca cgaatgaagc gcttaggagc cgtgttagct
    11401 ttcgctacat gtcctttagc aggtttgttg ctcaatactt cgcgtttgtc atcgaaacca
    11461 acttggatag cgttgtatcc gtctgtttca acagttttaa cttgaagaac aacgtttgga
    11521 gttgcttcaa taactgttac agggatcaat tcgccagctt cagtgaagat ttgagtcatt
    11581 cccacttttt tccctaagat tccttttgtc atgagaaaat agttcctttt ctatattttt
    11641 attcaaaaag tttttaacga gcgtttttta tgctcaagtc taagatacaa agggcgtcaa
    11701 actcaacgtg aaaataggaa actgacacag tgtctagcag acgcgaggaa gtttatcttt
    11761 ttcacaccga gtttagcccg tgttcaatta gattgaaaca ccagcctctg ctcttttata
    11821 ttttagatta aagtttgatt tctacgttta caccacttgg aagatccaat ttcatcaagg
    11881 catcaactgt tttttgagtt gggttaacga tatcgatcaa acgtttgtgt gtacgcattt
    11941 caaattgttc gcgagagtct ttgtatttgt gagtcgcacg aatgattgtg tagaggctac
    12001 gttcagttgg aagtgggatt ggacccgcaa cttgtgcacc tgtacgagta gctgattcta
    12061 cgatttttgc agccgctgtg tcaagcgtac ggtgttcgta agctttcaaa cggatacgga
    12121 tttttttgtt tgccatcttt ttctcctttt cgtctattta agataatagg ctagctccac
    12181 aagaaaaccg acgcggtgtt gcgtggcaat gcaaccgagc gtgtcgcaac ctcttgcatc
    12241 aaaactaagg ctgtaattta cagcaccata atagaataac acaaatcccc tgcgattgca
    12301 agggatttgt taggtttttt cgttttttgg ggatgaaact gttttcctac tttttctttc
    12361 taaaattagg gattttcttc tatatttctt ctatacataa gttaagtcct cttgacatca
    12421 aatttatctt ctgattggtc cactaagata tccgccttag actcagtttc tttatagtat
    12481 cgcagatact gctcccgtct catctgatgg ctagccaata taaaggatgc atcgcgattt
    12541 ctcacagtcg tatctctagc aaggcgtcgc tttaattcgg tctcctcatc cgtgtagaaa
    12601 cagatggttt tttcaaagag ttccttgggt agaaagccaa cagacatccc ttcgacaatc
    12661 aaaattggtt tggctccaga caagacctca ctagccttcc aaggttcttc aattgtcaag
    12721 acatccatac ccgcctgcaa ggcaaggata tctctctgca aactctccag ttcatgcgcc
    12781 actggcagac tggctgtcac cttttgattc ggcgcgtcct tgggtactac caaatagcgt
    12841 ccggaggtga tatagggatc tgtttctagc aaatttactg tagtagaatc taaagcttgg
    12901 tacaattcct gtgcaaaggt tgatttacct gaagctccat gaccgtatat tcccagtgtc
    12961 ctgactttcc ccgtctcgat ctctgagact agttggtcta ctaagtcttt tttcttcatt
    13021 ctctcttcac ctgttcatag atttcttttc cgtcattgag cttgtcccaa atcactactt
    13081 gcccactttt gagcgatttt tgcacatcga taattcgttg gttagacgaa cctcgaaact
    13141 ggagcataag atttctctta gttcgatcat atcttccatc gacaagaatg tcaatcagtg
    13201 acaagagttc cagtttatct ggagtttcca acatcatttc ttcccaagtg tagcccgtcc
    13261 aggaccagat gtccttgtct ggcaattcct tccgaatccg cttaacaagt ggcaagagaa
    13321 tcccagtatt aagaaaaggc tcccctccta gtaaggttaa cccctgaaca taaggctggg
    13381 caagatctgc cataatctgt tcttccaact cagctgtata gggaatgcct gcattgaagg
    13441 accaggtcgc tacattataa cacccctcgc agtgaaacat acagcctgct acatagagag
    13501 agttacgcac gccttcgcca tcaacaaagt taaaggcctt gtagtcaatg atacgacctt
    13561 gactaagttc ctcgcttttc cattcttgtg gttttggatt attcattcgc tacctctatc
    13621 caataacgct cgactccatt gcgagcatcc tcaaatattc caccatttgc tagaatgact
    13681 gctctgctag caggattatt cacgctacag gtcaccagag ctttcttgat gttcttttcc
    13741 ttagcaactt gcaagccctg acggagagtc tcttttgcat aacccttgcc tctttcagat
    13801 ggacggatgg agtagccaat gtggccagca taattcagta acccctcatt cagtctcaat
    13861 cgcagattca aaaatcctag agcacaacct gattcaccaa acaatacgaa ctgtatcgat
    13921 ggaacgcgat tttcaggtag ccatattccc atttctttat tacggttacc ttctagccac
    13981 tcctcgtaag aaaaatcctc aacatcccaa aatcctccat catgggctga ttggctcttt
    14041 tcaaactctg tcatcatatc taaaacagct ttcttatccg ctaatcttgg tctgcgtaat
    14101 tccatcctta cctcccacta tgagaaaagc gagagctggc tctcactttt attttttctt
    14161 gttcttgttt aaaaattgtt ctctgaagct aagcaagcgt tctttcttac cagctccacc
    14221 tttagagtgt ttctcgtgat aacgggtcac ttgtgcgcgc cccttatcgt ctagttgata
    14281 ttttcccatt tcatttcttt ctaatttgtt acttgatgcc cagctatttt aatcgttgaa
    14341 ccattcatat gtttgacacg cgcagcgatt tccttgtgac gcccgttgac catcggtctt
    14401 gcttgaggat tacctaggta gccacaagtt cgcttcacca catctactgt tttagggtcg
    14461 ctattgccac agtttggaca agcaaaccct ctctcagttg gttcaaaatc cccttcaaag
    14521 tcacacttgt agcaacggtc aatcggagta ttggtgccta gatagcctac acggtcataa
    14581 gcataatccc agacagcttc caaggccttt ggattttgct gaaggactgg atactcacaa
    14641 taatggatga aaccacctga cgcacctgct tctggataga ctttctcaaa gtccaatttt
    14701 tcaaacggtg ttggattttt acgaacatcg tagtggaaag agttggtgta gtattccttg
    14761 tctgtgatat caggaataga gccaaacttg tctatatcta gtcggcagaa acggtctgtc
    14821 agactttcgg atggtgttga gtagatagag aaatggtagc catattggtc tgaccactct
    14881 tctacacggc gtttcatatc gtgaatgatg tctagcgtga attccttagc atctggatta
    14941 ctttcccagc tgttaccaaa gaaaactgtc gctacttcat acaagccgat atagcccagc
    15001 gaaacggtcg cacgacaatt cttaaagagc tggtcaacac tttcttcttt acctagacga
    15061 tggccaaaag caccgtactg ataaaggata ggagcattcg ctggtgtcgc ctctttagtg
    15121 cgttcgacac ggtaaacaag agcatcttct gcgatattca ttcgctcgtt gaagatttcc
    15181 cagaacttat tcatatcacc ttcagactca agagcaatac gaggcagatt aaccgtcaca
    15241 acacccagat tcatgcgacc tgaattgact tctacaccat tttcatcctt ccatccttgg
    15301 aggaaagaac ggcaacccat aggcaccttg aaggatcctg tcaagtcaac aatcttatcg
    15361 taagataaaa catctggata catccgtttg gttgcacact caagagccaa ctgcttgatg
    15421 tcgtagttgg gagttccttc ctctaaatta aggcctcttt tcagagtgaa aataagttta
    15481 ggaaagatag ccgtacggtg ttctgaacca agacccttga tgcgaatgtt taaaatagct
    15541 ttttgaattt ctcgttcaaa acgactggtt cccagaccaa aacctagcga agtaaaaggt
    15601 gtttgtccat ttgaagtgaa gagagtattg atttcatact caagagattg catggcatcg
    15661 tagatgtcct tttgcgtttt cttccaagcg taatcttccc gtttttcagg caatacccac
    15721 tcttctgcat ctttgagatg tttttgatag ttcttctctg cataaggcgc caaaatttca
    15781 tcgatacggt cagctgaaca gccaccgtac tggctagaag caacgttggc aatgatttga
    15841 gaaatctgtg ctgtcgcagt ctggatagac ttgggactct ctacctctgc atttccaatc
    15901 ttaaaaccat tttccaacat acccttaaaa tcaatcaaac agcagttggt cataggggta
    15961 tagggactgt agtccaaatc gtgatagtgg atatccccct tttggtgggc attggctacg
    16021 tgcttaggaa gcatttgcag tccgattgat ttcccaacaa tccctgctgt caaatcacgc
    16081 tgagtgttaa agacatcact gtctttatta gcattttcat tgacaactgt ctggtctttg
    16141 ttgagaagtt tatgaatact aaagttgata tccgtcgctt ttgagcgctc aaaatccctc
    16201 tgtgtccgat aagtaatata ctcctcagcc agcgcatatt ctttggcttc aaggagttca
    16261 tgttctacga tattttgaat ttcgtaaatc ttaattccct gtggaaagcg actatgaatt
    16321 tctgtaataa ttctctcagt cagatcattg aggcgttttt caaccagggg tgtcacatcc
    16381 ataaccttgt cagctgcctt gtggagagcc ttgtcaatct tgtccacatc aaatacaaca
    16441 cgtctcccat ctcgtttctc gacgaagaga gttggcaaaa ttgtaatttt ttcttctagt
    16501 gcaatcatat gcatgctctt ttctaaaatg ttctttctaa aaagtattat accactctaa
    16561 aaagaaaaat caatatcttg tgttaaaaat cctaaaattt ttaaaaatac acaagatatt
    16621 gatttggtta tttaatttta tagactttaa actctgagta atcagtcttt acttgttggt
    16681 aattttcttt taaaagtgtt tccacttcag accagactac caccttgtca tttaccacaa
    16741 tcaccttagg ttgtttttct ttcaagtcat taagtaactt attacgattt tcctcagttg
    16801 ctgtatagtg caacggggac aaaatcgccg atggcgacaa gcgctcactc ttacgataaa
    16861 gagtcgcagt atcatcccat gcatagatag catcttccgt atttgtctcc tcttttacca
    16921 aatcagcaag acgattacgt tcttgataag gtactggata aaggacaaac ttcatcaaaa
    16981 aaggaacaga caaaagatag acaaacccaa aaactagcag atatagattt cctttgaaga
    17041 aacgactcca taggctaact ggcgtttctc ttcggcttct tctagcacta cgccccctct
    17101 gttgactctt gatattggtt accaataaaa gtaggaaaac agggaagacg accatcaaat
    17161 aagaagcgtg cagaggctct tgtgaaaaga aaagtaaaat caaacctaaa attaccacaa
    17221 gacttgcagg aaccgaaatg acgtatagtt taaagggttt ggattgaaag agacctaaaa
    17281 agatacaaac cacaaatccc aaaccaaggg acaacaagcc ataaaaaaac atattctcta
    17341 aaattttaga agtaaaatca aagcgaatac tgtcaatagg ataacgaata ccactaatcg
    17401 catccccaaa acttcctgtt gcagcactat agtaggcagt tggataaaag acaagtgaaa
    17461 aacctaaagc cactgcaaga aactgataaa acccatgcgc aaagcgtcta tgcccaaggt
    17521 taaagaccaa caagcctaaa ctcactacag caataaacag gagtgatgat aagggagcaa
    17581 agaaaaatcc gcctgccaaa gctaacccaa tccgtacaaa tcccttatca tggcttggat
    17641 tgcttaggta agccgcaact aaactaaagg ctgcgaataa gaaaggaagc gctaaaagag
    17701 tcgcatagcc tccaccaaaa gcaagacctg taactagcat gtaaaaaata gtcaccagat
    17761 gtccagcttg gtctccttgc tctgtcaagg tgtccgctga tctaaaaagg aaaaatcctc
    17821 ctgctaccaa ggctaaccac tcaaagatgg caaagaaaaa tccgccctga ctcacgtaag
    17881 tcagcaaata ataaagcaaa ccttgacttc cataatagtc gctgtaaatc ttccctgtct
    17941 gatgaagcgc ccaacctgca taaaaatcct gcacttcttg tgcactcatt aagtcgagta
    18001 atagcggtac tcctagagtt atccccgtta caagcgtact ccatagtaaa attttcacca
    18061 aaggaagacg acttgattca cgatgatgcg attcttgctc gatttggtat tctagaggtt
    18121 cacgattctc cttatgaact tcttctactc taccatacac actcatatcg tttctcctgt
    18181 tcaatttatc tgtcttagta tatcaaaaag tcctaggatt gtcagcttgc gatggctgtt
    18241 tgagtgattt tttgcatagt ttcacaaagg tttcaatttc ccgaaagcgg tgtaaatgtg
    18301 tctgtttgaa ctcaatcata tcattcactt cttccttagt tagcatgaat tcccctcctc
    18361 tttctttcta ttcgtaaaag acaagaaaaa taggtcgggt ttgtatccta agttctagat
    18421 ttcttataag ataggggcga atagctgggc gatttctttt acaagctttt gataccagct
    18481 cgttttgata gaatgaggat agacttcctg agaatctgca aatatatttc gaaaatctcg
    18541 ggcgatttcc cttatagaag gagttttata gagtaagact gcattttcat aatggtgtac
    18601 caagctccgg tagtcgagat tgattgtccc caccaccgca aaatcttcgt ctaccaacat
    18661 ctgcttacta tgaataaaac ctggactata ctcataaatc cgaacaccag cagaaagaag
    18721 gtcgggataa gctcctctcg tgactaactg aatgaacttc ttatctggta tgtaaggggt
    18781 gataattcga acatcgaccc ctctcatagc tgcatttttg attgtctctg ttaaatcata
    18841 atctataatc aaataaggtg tcgtaatata gaccgattcc gttgcttgat tgattaaact
    18901 ctgataaact tttttcccta cctgcgctcg aaaaattggc ttgggtccac ttccgtatgg
    18961 aatggttaaa ccgtcactcg ggatagaatg attttctaaa tgatattgat caaaatcact
    19021 aatttctcct cgattaatgt accaagtggt caaaaataag cgtgtcaggg cttttactgc
    19081 tagtccgtct aagcgaattc cactatcctt ccaataacca aatctctcga cgtggttaat
    19141 gtactcatct gccagattga ccccaccagt ataggctatc tgaccatcaa caatcaatat
    19201 ttttctatga tctctgttat tataagccac tgtcaaacga ggaataactt tattgaattt
    19261 atgggcctcg atgcccagct gacgaagtcg atgtgcataa tctcctgtta aagtagccat
    19321 acagccgata tcatcataga gcatcttaac ctctacaccc tgagctacct tttgctctag
    19381 tatatctagt atgcgattcc acatcaaacc ttcttctata atgtaatatt ccaagaaaat
    19441 aaatttctca gcctttttaa gatcttctac catctttttc cacatagctt ctccgttagg
    19501 aaaaaatgta gaggcagttt gatcatagat gtcagcattg gtatccatac tcaataagga
    19561 cttgatgact ccataagctg ccttgtcact ttcttttaat ttctctttta gtagctggct
    19621 atttgcttct tggaaatgca tagagcctag cttcttcagt tgtttgattt cttttttgga
    19681 caatcgcctt tcaccaaaca tcagatagag taagggacca aatactggca caaaggctac
    19741 taacaaccag gttaccttat tctcaggagt cgtattacgg ttgactatcg aaatgattgt
    19801 gatgatactc agtagaatga ggacagtaat ccataaaatg ggagccatgc gtcctaaata
    19861 aagaaagaga ccaaaaacaa gacaaagttc aagtagcata atcgaaagac taaagccata
    19921 cttggacatc aataattgaa atttcctata tttcatatcc cctccttgat agtttgaatg
    19981 ctaaaaacaa gtaattgata ctagtataac gcaggtattc ggtagaaggc aagtatttat
    20041 gattattttc taggtaaaag taaaaaggct gaaaaatcca gccctttcta cttgcatagt
    20101 cttatttagt taaaacgatt tggtccgatg ggtctctatc catatcatct acgacgattt
    20161 gattaccgtt tacagtgtaa attttgacat catcgccaat aatcatgcgt tgatttgctg
    20221 aatcaaatgt aacctgtttg actttctgat ccccgtcaga ttcgagctca gtccatgtac
    20281 cagtcgttcc agttaccact aaagtgatac ggtctccgtc atcctgacca gtataagtcc
    20341 catcaatatc ggtcggttga gcaacaggtt ggttttgtac tggagccgct tgattttggt
    20401 tacctcctgc atttgcagta ttggtattct gttgagcagg ttgttgagca ggctgttgga
    20461 cctgctgctg agcaacaggc tgttgaacct gttgagctct ttgtgaacaa gctactaaga
    20521 gactaaaact tgctagagaa gcaagagaaa gtgtgaatct ttttaatttc atgatgaatt
    20581 tcctttctgc taccaattta gagaaatttt ctctaaccag caattcccct agtataacaa
    20641 gttcaaacaa gggggtcaat ttatctgctc acggtccagc aggtagcccc gtacttctga
    20701 gataaaatag agagaccctg taacgaacag caagtcttga gcgtctgccc tttcttcgaa
    20761 actgctgata aattctcggc aagaagaaac tatatcgtaa cctgtcacat ccctttcgtc
    20821 caaagccccc tgatagtcaa agccggtcac cttgagttcc acctgaggca atttttcagt
    20881 caggtaacct aacatccctt gataatcctt ccgtttcaag gctccaaaaa ggatttgagg
    20941 tcgatagcct tcctgctctt tttctttgat aaactcaacc aagcgagtca aggcagggag
    21001 gttatgagca ccatccaagt aaatctgtgg gcgaatacgc tccaagcgac cagcccaatg
    21061 ggtctgttcc aaggcctttc ttacagcctg ttcatcaaca gcttcctttc cttctcccat
    21121 aaaaagaaga aaagtttgca acgccaaggc tgcattctcc tgctgataga ctccttctaa
    21181 gcctatgttc agctgtgaaa aatttagtaa agagcttgaa aaatcaccat tcagcattaa
    21241 aaaatcttga cctgcctgat aaaggttaac agctaaagat tcggcttttt tctgacagac
    21301 aagcctagct tctggaggca atttcgcaat cactgccttc ttaccagcct tgaaaatacc
    21361 agctttctgc tctgcaattg cttctagact atcacccaag gtttcttgat ggtcaagccc
    21421 aatggaggtg atgacagcaa gctctccagt taccacattg gtcgtgtcaa gtaagccacc
    21481 aattcccact tctaataaaa ccaaatccac ctcttgctcc ctaaaataaa gaaaagcaac
    21541 caaggtcagc atttcaaaaa aggacaactg gtcaggagtt tgcagaagcg ttttctccat
    21601 ctccttgacc tgatcagcca aacggataaa gtctgcgtct gctataggtt gcccattaat
    21661 gcagattcgg tcattgatag agacgatatg aggggaggta aaggtcgcaa cttttttgcc
    21721 atgccccata aataattccc tcataaaagc aatggtagat cctttcccat tagtccctgt
    21781 tacgtggata atagggtaag actgctcagg atttcctaac aaatccaccg cttgctgtat
    21841 tcggcccaaa cctgatcgaa aattcaaacc aatccgacta tgaagccatt cttctacttc
    21901 aaacatacac atctccttga caaaagtcca atcaattatc gcattaaagt atggttacta
    21961 ataaaaacaa ggccaggatt ttcgtcccga cctcttacct ggttagctaa taactagcca
    22021 ctatgaatgt gaatatgggc taaaaacatc cactagatgt tccaactctt ccccatttct
    22081 gggagttggg ctgatacagt ctcccagact gtatcactcc tccataaagc tgttgaagac
    22141 ttcttcaatc atgttccatt cgtcttctga gtcttctggg attggttgca attcgccttc
    22201 tgttccatct tcattttcaa tgaatgagta agcttggatt tcaacttgtc cgtcttcgtc
    22261 ttcttctgcg ttaactggta ctagaagaac atagttttta ccaaattctt cttttccatc
    22321 aattgtcaaa aggatttcaa acaaggtttc atttccttgc tcatctacta gtgtgattag
    22381 ttcacgttct tcgtggtcgt ggttatgatc gtgtgacata gcctctcctt tatattaaaa
    22441 ttttctatct aaataatttt gtaaaatcag ctgagctgct aacttatcaa tgactttctt
    22501 gcgcttattg cgactgatat ctgcttgttc aatcaacatg cgctcagcag ccactgttgt
    22561 caagcgttca tcctgatagt ctaatggtaa accaaaaaac tcttctagct ttgctccgta
    22621 ggcttgacta gcttctacgc gcggtccact tgtattgttc atgtttttag gcaagcccac
    22681 tacaaatcgt tccaccttgt aagtatcaac caattcctta acgcggtcaa aaccaaattg
    22741 gccttgttct tcatttatct ggatgatttc aagcccttga gctgtaaaac caagcggatc
    22801 gctaatcgcc acccctaccg tttttgaacc gacgtccaat cccataattc tcataggtta
    22861 tagatcgact ccttgtcctt tgaggtagta gcgaaccaat tcctcaacga tttcatcacg
    22921 ctcatactta cggatttgat ttcgtgcatt attataacga ggaacgtagg cagggtctcc
    22981 actcaatacg taacctacga tttggttaat tgggttgtaa cccttatcgt tcaacgaagc
    23041 ataaacatct gtcaaagttt cgctaatttc ttttttattg gaatcgtcca atttaaaacg
    23101 tactgtttct tcagtaaatc ccattctaac accctctttc cttagaatag taccattata
    23161 gcataattcc ttaccttcta caattcaggc agtctattta tttggatttt ctattgttct
    23221 gtcgcgccat ttgccaatct atctgaaata tatttgcttg gttcattttt caaaagattt
    23281 tccaaaccaa tattcttcag atgttccaac tgggaagcct tcttgacatc cagaacttga
    23341 aaatcaaaac tagtcgttgt ttgaagttcc gttgcgctca atagttttgt ttcaagtttg
    23401 aaacctgcca atttacgagc ttcaatgata gacttatcct tctcctccgc ttcaagaaga
    23461 gctttttgag tttcctccac tccatgttgg tcaatataag tcttcaactc atcagagact
    23521 ggacgttttt gttggatagt tagactcaaa aaagtcttgt ccttgtatgt aatggtttgt
    23581 gtctgctggc taccatcatc tgacttgggc aagaccaaag tcttagttac aactgtattc
    23641 ttctcagcat tttcaataac tggcaatgcc gactgaagcg tatctttttc tgtttttgta
    23701 gctggtccag tttctttttt ctgtccgcaa ccaaccagga caaaaaggaa agctagacta
    23761 acaagaacta tttttttcat ttctttcttc tttctttttg aaattaaaat agaataagac
    23821 tgggaagtgc tcccagcctt gatgtttata gagctgcacg caaacgtgct tctgcatttt
    23881 ctacattacg gacagagcgt ggtaggaagg cacgaatatc gtcttccttg tagccaactt
    23941 gcaggcgttt ttcatctaca aggattgggc tctttaaaat tctcggtgtt tccataatca
    24001 gattgagaac ttcattgaca ctcaaatctt caatatccac tccaagggct ttggcatagc
    24061 gatttttaga cgaaacgatg ctggctattc cgttatctgt tttggttaga atatccagta
    24121 attcttctct cgtaattcct tctttaccaa ggttttgttc tttataactt aactggtggg
    24181 cattgagcca ggtttttgct tttttacagc tagtacaact tgagactgta taaattttaa
    24241 tcatgtacct acccctttcg ctacatgtta ctatcagttt agtctattat accataaaaa
    24301 acatccgact tgcgacctat ttttaat
//
LOCUS       DAVBEM010000032        23965 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVBEM010000032 DAVBEM010000000
VERSION     DAVBEM010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23965
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.032"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(255..2513)
                     /locus_tag="VQ548_001326"
     CDS             complement(255..2513)
                     /locus_tag="VQ548_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2654172.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2742..2972)
                     /locus_tag="VQ548_001327"
     CDS             complement(2742..2972)
                     /locus_tag="VQ548_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HET2654173.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3162..3845
                     /locus_tag="VQ548_001328"
     CDS             3162..3845
                     /locus_tag="VQ548_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2654174.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSEIVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3845..4579
                     /locus_tag="VQ548_001329"
     CDS             3845..4579
                     /locus_tag="VQ548_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2654175.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDIAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4733..5590
                     /locus_tag="VQ548_001330"
     CDS             4733..5590
                     /locus_tag="VQ548_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HET2654176.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGYRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5732..6604
                     /locus_tag="VQ548_001331"
     CDS             5732..6604
                     /locus_tag="VQ548_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HET2654177.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLMTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVILLGPGL
                     GDNAFGEDLVKQVFAGLKQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            6886..7569
                     /gene="rpiA"
                     /locus_tag="VQ548_001332"
     CDS             6886..7569
                     /gene="rpiA"
                     /locus_tag="VQ548_001332"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HET2654178.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7583..8794
                     /locus_tag="VQ548_001333"
     CDS             7583..8794
                     /locus_tag="VQ548_001333"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HET2654179.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8796..9338
                     /locus_tag="VQ548_001334"
     CDS             8796..9338
                     /locus_tag="VQ548_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HET2654180.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9354..10163
                     /locus_tag="VQ548_001335"
     CDS             9354..10163
                     /locus_tag="VQ548_001335"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET2654181.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10639..11619
                     /locus_tag="VQ548_001336"
                     /pseudo
     CDS             10639..11619
                     /locus_tag="VQ548_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855254.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            11644..12156
                     /locus_tag="VQ548_001337"
     CDS             11644..12156
                     /locus_tag="VQ548_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HET2654182.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPISAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            12803..13513
                     /gene="deoD"
                     /locus_tag="VQ548_001338"
     CDS             12803..13513
                     /gene="deoD"
                     /locus_tag="VQ548_001338"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET2654183.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13536..14060)
                     /locus_tag="VQ548_001339"
     CDS             complement(13536..14060)
                     /locus_tag="VQ548_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HET2654184.1"
                     /translation="MKIAIIGYSGSGKSTIAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(14113..14349)
                     /locus_tag="VQ548_001340"
     CDS             complement(14113..14349)
                     /locus_tag="VQ548_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HET2654185.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14417..15337)
                     /locus_tag="VQ548_001341"
     CDS             complement(14417..15337)
                     /locus_tag="VQ548_001341"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HET2654186.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15527..15931
                     /locus_tag="VQ548_001342"
     CDS             15527..15931
                     /locus_tag="VQ548_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654187.1"
                     /translation="MKILKRYILELCFILSFALPFIKGTNADNGRCFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            16147..16728
                     /locus_tag="VQ548_001343"
     CDS             16147..16728
                     /locus_tag="VQ548_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2654188.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGQKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            16725..18002
                     /locus_tag="VQ548_001344"
     CDS             16725..18002
                     /locus_tag="VQ548_001344"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HET2654189.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVHQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            18020..18682
                     /gene="deoC"
                     /locus_tag="VQ548_001345"
     CDS             18020..18682
                     /gene="deoC"
                     /locus_tag="VQ548_001345"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HET2654190.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18669..19058
                     /locus_tag="VQ548_001346"
     CDS             18669..19058
                     /locus_tag="VQ548_001346"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET2654191.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19148..20200
                     /locus_tag="VQ548_001347"
     CDS             19148..20200
                     /locus_tag="VQ548_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HET2654192.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALNNAVKDAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20344..21879
                     /locus_tag="VQ548_001348"
     CDS             20344..21879
                     /locus_tag="VQ548_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2654193.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            21872..22930
                     /locus_tag="VQ548_001349"
     CDS             21872..22930
                     /locus_tag="VQ548_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2654194.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            22933..23889
                     /locus_tag="VQ548_001350"
     CDS             22933..23889
                     /locus_tag="VQ548_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2654195.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         6956 a         4329 c         5459 g         7221 t
ORIGIN      
        1 tgcaatacct tttacgaggc tcttttgtcc tgctcttgtt tcaattgact atagcagatt
       61 gaaataagat gagaacaaat cgattgggaa agtaaaatta atttctataa atgttttagc
      121 aattgtttcg tactatttca gattcagtct actatatatc ataatggaca aagggcaagc
      181 tgtcaagaaa ttacagttat tttagtaaaa aaagaagcag aaaaatttaa ttttctactc
      241 cttttctata ggatttattt ttctttttca gaacttttaa cttcagcttt tttggcagat
      301 ttaatctgaa tgtttccctt gctagtcata actgctttga gatctttttc gcttggattt
      361 tcaaggtagt agtcagtgat tgtgtcctca atatagtctt gaatagtccg acgaagtggg
      421 cgtgctccca tttttggatc ataacctagg tcaaccaact tttccttgac cttgtcagtt
      481 acatccaaac gaatgttgtt gctagagagg cgcttgttaa catctgctag catgagctcg
      541 acaatctgaa ggaggttatc cttgctgaga gccttaaatt cgataatgcc atcaaaacgg
      601 ttcataaact ctgggctaaa gaagttaccg agttcaccga ggacagaatt ggtacgtcct
      661 tctctagcag caccaaatcc aacgctagct tcggtctttc ctgtacctgc atttgaggtc
      721 atgataatga tggcatcctt gaagctaacg gtgcgtcctt gcccgtctgt caaacgacca
      781 tcgtccaaga cttgaagaaa catgtgcata acatctgggt gagctttttc cacttcatcg
      841 agaaggatga gagaatatgg attgtggcga actttttcag ttaattgacc agcctcatca
      901 tagccaacat aacctggagg agcgccgacc aacttagcca cactatgttt ttccatgtat
      961 tcactcatat caaagcgaat catactatca gcagaaccaa aaagttcgat agccagttgt
     1021 ttggaaagtt ctgtcttacc gacaccagtt ggcccaacga agaggaagct tccgattggg
     1081 cggttagggg taccaagtcc gacacgatta cggcgaatag ccttggcaat cttatcgact
     1141 gcatcatctt ggccaataac atgagacttg agatcttcgg ctagatggat gagttgagat
     1201 tgttctttct ctttcaaatc accaacaggg atattggttt tctgctcgat aatgtgctca
     1261 atagttttct cgctgatgat aggagtatcc tggtctgtga tctttttctt ttgcatttcc
     1321 ttatacttgg caatctggtc gcggaagtag gccgccttct caaaatcttc ttctcgtgta
     1381 gcttgagact tgagattttc agcctcaatc aagcgctgat caattacttt aggatccaca
     1441 aaattcaagg tcaagttcat cttagaacca gcttcatcta ggaggtcaat ggccttgtca
     1501 ggcaagaagc gatcttggat gtagcgattg gaaagagttg cagctgcttc aatcgcagca
     1561 tctgtatatt gaacgtggtg gtaatcttcg tatttctttt gaatcccttt gagaatagtg
     1621 attgtttcgt ccaccgttgg ttcatcgact ttaacaggct gcatacgacg ctcgagggca
     1681 gcatcctttt caatgatacg gtattcattg agggtagtag caccgactag ttgcagttct
     1741 ccacgagcaa gggctggctt gaggatattt cctgcgtcca tattaccatc actcgcagaa
     1801 ccagcaccaa caatttcatg gatttcatcg ataaagagga tgatgtcttc acgtttgcga
     1861 atttcttcca tgagtttttg catgcgttct tcaaattgtc ctcgaatccc cgttccttga
     1921 actaagctaa ccacatccag acggatgact tgtttacctt ggagtttatg tggcacatcg
     1981 ccatcgacaa ttttctgagc tagaccttcg acaacggccg tttttccgac accaggttca
     2041 ccgataagga caggattatt cttggttcta cgattgagaa tctcgatgac acggataatc
     2101 tcatcgtcgc gcccaataac ggggtcaatg tctccacgac gggcaatttc agttacatta
     2161 ataccaaatt cttccagcag gcctttttct tggctaggtg gcggagtttg agcagatcca
     2221 cgattttggg aaccataacc gccgtttcca ccgtaacctc cacctgattg ggttggggga
     2281 ataggaggag tattgctaga aggtctgaaa ttgtttagat cattgaagaa atcaccaaag
     2341 ggatcgaagt cacgattgtt cagatccgtc atacctttga agaggctatt gttaggatct
     2401 gttttgataa tcttatagca gttttgacag aggtcaattt gtttttgttt tccattgaga
     2461 ttggtgtaaa gatgaattgt tgagtcgtta attttacagt tttgacaaag catacatcta
     2521 cctcatttct ttctttagcc tgacttgttt aaaggtcaaa aatagtcaaa ttctatactc
     2581 tcattataac aggattgggg tgtaaagcaa gtaaaaagat tgaagctttg agaagttgtt
     2641 acaatgaaaa tttttgtgaa tttggactat aaaaaaatcc tatttgtgag acaaaaagga
     2701 ttttacttag acatgcaggg acaatcccag cttgttttag attagtagag aagttcgtaa
     2761 atttccattg cgattaagtc aatgctatca aacgtatacg tttcgcgatc ttctacgtca
     2821 cgaagggtaa agattgggcc gttttcttcg tcgtggctgt acgcaacttc tgcaacaaca
     2881 actccttcgc gttcaaaatt acgttttaaa tttccgccat cgtttgccat tgcttcaagg
     2941 cggttgatga ttctaaccaa atgtgattcc attttgattc tccttcattt cttatcgtta
     3001 ctattttacc ataaaggagg ccaacttgac tagaaaaaac taagatttct cgctaattct
     3061 gctagtttaa agatttttaa ataaattgga taaaaaattt aaattttaat tcaaaacatg
     3121 ttataatcat acagtattct attttagaaa gcagtgtgac tatgaatttt tcttttttac
     3181 ctaagtattt accttatttt aactatgggg ctgttgtgac gattcttatt tctatctgtg
     3241 ttatcttttt gggaactatt ttgggtgttg tcttggcttt tgggcaacgt tcaaagttta
     3301 aaccgcttgt ttggttggcc aacttgtacg tttggatttt ccgtgggaca ccgatgatgg
     3361 ttcaaattat gattgccttt gctcttatgc atatcaatgc tccgactatt cagattggaa
     3421 ttttaggtgt tgatttttcg cgtctgattc cagggatttt gattatctct atgaatagtg
     3481 gtgcttatgt ttcggagatt gttcgtgccg gaatcaatgc ggttccaaaa ggtcagctag
     3541 aggcggctta ttcgctaggg attcgtccta aaaatgcgat gcgttatgtg attttgccac
     3601 aagcagtcaa aaatatcttg ccagcattgg ggaacgaatt tatcaccatt atcaaggaca
     3661 gctccctctt atcagctatt ggggtcatgg agttgtggaa tggggctaca acagtttcta
     3721 caacaaccta tctaccttta acaccacttt tatttgcagc attttactac ttgattatga
     3781 cctctattct gacagtagcc ttgaaagctt ttgaaaaaca tatgggacaa ggagataaga
     3841 aataatgaca gaaaccttga taaaaattga aaatttacat aaatcttttg gaaagaatga
     3901 agtattgaag ggcatcaacc tcgagattaa aagaggagaa gttgtcgtta tcatcggtcc
     3961 ttcagggagt gggaaatcta ccttgcttcg ctctatgaat ttgttggagg aagcaaccaa
     4021 ggggaaggtt atctttgagg gagtcgatat tacggacaag aagaatgacc tgtttgccat
     4081 gcgtgagaag atgggcatgg ttttccaaca atttaacctc tttcctaata tgactgtgat
     4141 ggaaaatatt accttgtcac ctatcaagac taaaggtgaa agcagggaag ttgctgagaa
     4201 gagagcccaa gagcttttgg aaaaagttgg tttgccagat aaggcagacg cttatccaca
     4261 gagtctgtcg ggtgggcaac aacaacggat tgccatcgcg cgtgggttgg ctatggaacc
     4321 agatgttttg ctctttgacg aaccaacttc agccttggat cctgaaatgg taggtgaggt
     4381 attggctgtt atgcaagaca ttgccaagtc agggatgact atggttatcg taacacatga
     4441 gatgggattt gcccgtgagg tggcagatcg tgttatcttt atggcagacg gtgtggttgt
     4501 tgaagatggg acacctgagc agatttttga acaaacccaa gaacaacgga ctaaagattt
     4561 cttgagtaag gttttataat ctattttaaa atttcaagac aagattagtg aaaagttcaa
     4621 ccagagcttt ttcttatagt ttgaaactat aggataacct aggaaagaag tgttagaggg
     4681 cactagcagt ttttggtata atggaagata tttgaaagaa aagagaagtg atatgacaca
     4741 gattattgat gggaaagctt tagcggccaa attgcagggg cagttggctg aaaagactgc
     4801 aaaattaaag gaggaaacag ctctagtgcc tggtttggta gtgattttgg ttggggataa
     4861 tccagccagc caagtctacg ttcgcaacaa ggagaggtca gctcttgcgg ctggttaccg
     4921 tagcgaagta gtgcgagttc cagagaccat tactcaagag gaattgttag acctgattgc
     4981 taaatataat caggatccag cttggcatgg gattttggtc cagttgccat taccaaaaca
     5041 tatcgatgaa gaggcggttt tattagccat tgacccagaa aaggatgtgg atggtttcca
     5101 tcccctaaac atgggacgtc tttggtctgg acatccagtc atgattccct cgacacctgc
     5161 aggaattatg gaaatgtttc atgaatatgg gattgacttg gaaggtaaaa atgcggtcgt
     5221 aatcggtcgt tcaaatatcg ttggaaaacc tatggctcag cttcttttgg ctaaaaatgc
     5281 gacagtaacc ttgacccact cacgaactca taatcttgcc aaggtggctg ctaaagcaga
     5341 tattcttgta gtcgcaatcg gccgcgccaa gtttgtgact gctgactttg tcaaaccagg
     5401 tgcggttgtc attgacgttg ggatgaatcg agatgaaaat gggaagctct gtggagatgt
     5461 tgattatgag gcagttgcac cacttgctag ccatatcacg ccagtccctg gaggtgtcgg
     5521 tcctatgacc attaccatgc tgatggagca aacttatcaa gcagcacttc ggacattgga
     5581 tagaaaataa gagaagcatt cgattaatag agtgtatttt ctatagctat atctaaaatg
     5641 gcagaaatga atattaaatt ttagatataa gattacaaaa ggaggtctgc gtctcctttt
     5701 tattgtataa taaaagtgag aggaaaaaag gatgaaagtg attaatcaaa ccttattaga
     5761 aaaagttatt attgaacgtt ctcgttcaag tcataaagga gattatggtc gtctgctgct
     5821 gcttggtggt acttatcctt atggaggtgc catcatcatg gctgctttag cagctgtaaa
     5881 aagcggtgca ggattgatga ccgttggaac ggacagggaa aatatcccgg ctctgcacag
     5941 ccatttacct gagcctatgg ccttttctct tcaagaccag caattgttaa aagagcaatt
     6001 ggagaaggca gaagttatct tgctggggcc tggtttagga gacaatgctt ttggagaaga
     6061 tttagttaaa caggtctttg ctggcttaaa acagaatcag attttgattg tagacggagg
     6121 tgccttgacc attcttgcta ggacaagttt gtcatttccc tcaagccagc ttatcctaac
     6181 tcctcaccaa aaagaatggg aaaaattatc tggaattacg attgaaaagc aaaaggaaga
     6241 tgcaacggct agtgttctga cttccttccc tcaaggaaca attttggtgg agaaaggccc
     6301 agctactcgt atttgggaag ttggccaatc tgattattac cagttacagg ttggtggtcc
     6361 ttatcaggcg actgggggaa tgggagatac tctggctggg atgatcgcag gatttgtagg
     6421 ccaattccga caggccagtc tctacgagcg tgtggcagta gcgacccatc ttcattcagc
     6481 catagcccaa gaactatctc aagaaaatta tgtggtctta ccgacggaaa tcagcaggta
     6541 tcttcccaaa ataatgaaaa ttatttgtca acaagagagg gtaagcaaag ataaacttgt
     6601 ttaaaataga cagataaatc tacttccttc tcttaattta tgattcttga aatgcgcctg
     6661 ctttaaggct aaactagacg tatcaaagtt aagagtttgt ttttgtaact ggaaagagat
     6721 gaacaaatca aatacataaa agataaactc atttttattc gttttgtaaa aataaaatgc
     6781 atatttttaa agaaagattg atgaaaaatg tagatttgat gtttttactt gaataaaaag
     6841 cggtttcata gtaaaataag aactgagaat gatggaggta aatcggtgga aaatctgaag
     6901 aaaatggcag gtatcaaggc tgctgagttc gtgagcgatg gaatggtcgt tggacttgga
     6961 acaggctcga ctgcctatta ttttgtcgaa gaaatcggtc gtcgtatcaa ggaagaagga
     7021 ttgcagatta cagctgtaac aacttctagt gtgaccacta aacaggcaga aggccttaat
     7081 atcccgctca agtctattga ccaagtagac tttgtcgatg tgacggttga tggcgcggat
     7141 gaagtggata gtcagtttaa tggaatcaaa ggcggtggtg gtgcccttct catggaaaag
     7201 gtggtcgcaa caccatcaaa agaatacatt tgggtggtgg atgaaagcaa gctggtcgaa
     7261 aaactaggtg cttttaaatt gccagtagaa gtggttcagt atggtgcaga gcaggtcttt
     7321 cgtcattttg aacgagctgg ctacaaacca agtttccgtg aaaaagacgg tcaacgtttt
     7381 gtgacggata tgcagaattt tatcattgac ctcgccttgg atgtcattga aaatccaatt
     7441 gcttttggac aagaattgga ccatgtcgtt ggtgttgtgg agcatggttt attcaaccaa
     7501 atggtggata aggtaatcgt tgctggacga gatggagttc agatttcaac ttcaaaaaaa
     7561 ggaaaataga agggggcata agatgtctaa atttaatcgt attcatttgg tggtactgga
     7621 ttctgtagga atcggtgcag caccagatgc taataacttt gtcaatgcag gggttccaga
     7681 tggagcttct gacacactgg gacacatttc aaaaacagtt ggtttgaatg tcccaaacat
     7741 ggctaaaata ggtcttggaa atattcctcg tgaaactcct cttaagactg tagcagctga
     7801 aagcaatcca actggatatg caacaaaatt agaggaagta tctcttggta aggatactat
     7861 gactggacac tgggaaatca tgggactcaa cattactgag cctttcgata ctttctggaa
     7921 cggattccca gaagaaatcc tgacaaaaat cgaagaattc tcaggacgca aggttattcg
     7981 tgaagccaac aaaccttatt caggaacggc tgttatcgat gattttggac cacgtcagat
     8041 ggaaactgga gagttgatta tctatacttc agctgaccct gttttgcaga ttgctgccca
     8101 cgaagacatt attcctttgg atgaattgta ccgtatctgt gaatacgctc gttcgattac
     8161 ccttgagcgt cctgcccttc ttggtcgcat cattgctcgc ccttatgtag gtgaaccagg
     8221 taacttcact cgtacggcaa accgtcgtga cttggctgta tctccatttt ccccaactgt
     8281 tttggataaa ttgaatgagg ctggtatcga tacttatgct gtgggtaaaa tcaacgatat
     8341 ctttaacggt gctggtatca accatgacat gggtcacaac aagtcaaata gtcatggaat
     8401 tgatacacta ttgaagacta tgggacttgc tgagtttgaa aaaggattct cattcacaaa
     8461 cctagttgac tttgatgccc tttacggcca tcgtcgtaat gctcacggtt accgtgattg
     8521 cttgcatgag tttgatgaac gcttacctga aattatcgca gctatgagag agaatgacct
     8581 tctcttgatt actgcggacc atggaaatga cccaacgtat gcaggaacgg atcacactcg
     8641 ggaatatatt ccattgttgg cctatagccc tgcctttaaa ggaaatggtc tcattccagt
     8701 aggacatttt gcagatattt cagcgactgt tgccgataac tttggtgtgg aaactgctat
     8761 gattggggaa agtttcttag ataaattggt ataagatgac gcgctatgct ttgctggtga
     8821 gaggtatcaa tgttggtggt aagaataagg tcgtcatggc ggagcttcgt caagaattga
     8881 caaacttggg actggaaaag gttgagagct acatcaatag tggcaatatt ttctttactt
     8941 cgatagattc caaagcccaa ttggttgaaa agctagagac tttctttgca gtccattatc
     9001 catttattca gagcttttct ttactgagtc tagaggactt tgaggcggaa cttgaaaatc
     9061 taccagcttg gtggagcaga gacttggcac gaaaagattt tctcttttac actgagggtt
     9121 tggatgtgga ccaagtcatc gcgacagttg aaagtttaga gctgaaagat gaagtgcttt
     9181 attttggaaa acttgggatt ttctggggga aattttctga agaatcctat tctaagactg
     9241 cctatcataa gtacttgctg aaggtgcctt tctaccgcca cattactatt cgtaatgcta
     9301 aaacctttga caaaattggt caaatgctaa aaaaataata aaggagacac acaatgacat
     9361 ttttaaacaa aatccatgaa actgctactt tcctgaaaga aaagggaatt gcagcccctg
     9421 agttcggtct aatccttgga tcaggacttg gagaattggc agaagaaatc gaaaatccag
     9481 ttgtagtaga ctatgctgag attccaaact ggggccgttc aacagtagtc ggtcatgctg
     9541 gtaaattggt atatggtgaa ctggcaggtc gcaaggtctt ggctcttcaa gggcgtttcc
     9601 atttctatga agggaatcct ctggaagtgg tgactttccc agttcgtgtg atgaaagttc
     9661 ttggatgtga aggtgttatt gtaaccaatg cagctggcgg tatcggattt ggtcctggta
     9721 ccttgatggc tatctcagac catatcaaca tgacggggca aaatccattg atgggtgaaa
     9781 acttggatga ctttggccca cgtttcccag atatgtctag ggcctacaca ccagaatacc
     9841 gtgccactgc ccatgaagtg gctaaaaaac ttaatatcaa gcttgatgaa ggtgtctata
     9901 tcggagttac tggtccgact tatgaaacac cagcagaaat tcgttcctat aagacactgg
     9961 gagcagatgc agttggtatg tctacggttc ctgaagttat cgtggcagcc cactctggct
    10021 tgaaagttct gggaatttca tgtatcacta actttgcggc cggtttccaa gaagaactca
    10081 atcacgaaga agttgtagaa gtgactgaac gtgttaaagg tgatttcaaa ggcttgctta
    10141 aagcgattct tgctgaattg taagaaaaaa gatttaaaag ggggagtgcc tctgtttttt
    10201 caggattgac tgcctatccg gattaaagaa gaaacagagg aatactatga gcttcttcct
    10261 gctcttataa ctgaaagaag cggaagaata ggtatgtctg atctgatagc cagcattgtg
    10321 aaagacaaga ttctaggata ctagcattag cttcctagcc aagcagacta gtatgataag
    10381 gagagatgag aatgaattga ctttctgaat ttctcagtct tatcatatat agcacaatga
    10441 gatttcgctt gagtctgctt gtaaataaac gaaaagaaag ataagaaata atgaaaattg
    10501 gtcaacgaat tatgcgcttt ggcataaaaa attaagtatc ggagttgtat ctgttgtagt
    10561 cggctttgat ttctagctcc agctggaatt tcagccaatg aagtaaagca agatgtaaca
    10621 tctgaagtgg taataggtgt gctagattct aaggaggaat tgaaagagtc agaaaatgat
    10681 gctccaaaac tagaaactcc tcttagagag gagccaagac tagctcctca aacgcttccg
    10741 gaagcaagtg aagttcttga aaacaaaagg gaagagtcaa aagtagagat aacataacca
    10801 gctcaagcgg atgatatccg caaggttgtt ggggaattag ccaaggatat aagtattact
    10861 aagttgtata tgacaggtca ttctcttgga tgttacctag ctcagattgc agcggttgaa
    10921 gcttaccaaa aatatcctga tttttataac catgtattga ggaaagtgac aactttcagt
    10981 gctcctaaag tgattacttc cagaactgtt tggaatgcta agaatggttt ctgggatgtt
    11041 ggtttggaaa gtcgtaaatt agctgttagt ggaaaaatta agcattatgt ggttgataat
    11101 gacaatgttg tgactccctt gattcataat aatcgtgata ttgttacatt tacaggtaat
    11161 tcacgcttta aacaccgttc tcgtggctat tttgaaagtc caatgaatga tattcctaac
    11221 tttaatattg gtaaacaagc taccttggat aaacatggtt atcgtgatcc gaaattggat
    11281 aaagtgcgat tctttaagaa acaggctctg cctcgatctt ctagtcaacc aagcgctgaa
    11341 ccaatggaaa atattgcctt aggaaaacag gttactcaaa gttcgacagc tttcggagga
    11401 gatgctagaa gagctgtgga tggcaaagtc gatggtaact atggtcacaa ttctgtcact
    11461 catacaaact tccaatctaa gccttggtgg caagtagatt tggctaaaga agaaaccatt
    11521 cgccaaatca atatttacaa ccgaacagac actgcccagg atagattggc aaactttgat
    11581 gtcattcttt tagacagttc tggtaaagaa attgagtgaa aacgtataat atctcctaaa
    11641 gatgtgtcag cacaaattac gattaaccat aaaaaagcgc gctatgttcg gattgagcta
    11701 gaaggctata atgccctcag tcttgcagaa gttgaagttt tccgctttat agctacgaat
    11761 gctgaaacgg cgacacaagt ttctaagcca gttcaaccaa tcagtcagac tcctgtgaaa
    11821 gataaaacat tgacaattca acacagtgga gcttacattg cccgctactc cataacttgg
    11881 gaagaagttc cagtagataa agatggaaac caagttgttc gtagtcattc ttgggaagga
    11941 aacggtcgca accagactgc gggttttgtc ctcaacctcc caatcaaaga aaatatgaga
    12001 aatctgcgag ttaagattga gaaaaagacg ggcctactat ggaatagatg gcaaacaatc
    12061 tatgaaaaca gaccaatttc agctcaaccc caccgtaaaa ttacccattg gggtacgaca
    12121 ttgaattcca aggtgagtga cgatgatgtc ttgtaatctg atggtacaat gacagttagt
    12181 ttgtctagtt tataagaaag tactacctga gcttgaatag aactcaggta gctctctgtg
    12241 aaagaacaaa attaatactc aatgaaaatc aaagagcaaa ctaggaaact agccgcaggt
    12301 tgctcaaagc actgctttga ggttgtagat aagactgacg aagtcagtca catatataat
    12361 ccaaggcgac gttgacgtgg tttgaagaga ttttcgaaga gtataaacag aaaggtagag
    12421 cgcgtgttct aatttgaaca cgagtagaaa acttttctaa aaacaaaaac gaaaggatgg
    12481 gtaaactgta ttcgctgaac tgaatacggg cgactctcct ctaaatcaaa attaagaaag
    12541 gaattgaccc caccctaaaa gtagtgggaa aaagatagtt ggtctagcga gcatcgctca
    12601 ctgcgcccaa ctcctatttt cccttcgctt tttgatgggt ttggtatctt tctcaatata
    12661 aaataaagaa aggtagagcg tgtgttttga tttgaacacg agcggaaaac tcggaaaata
    12721 gataatctga ctgaaaaatc aggatttctc gtcaggttcc taattttcag tcgttttctt
    12781 ctcgctcttt gtatcataaa ttatgtctat ccatattgct gctcagcagg gtgaaattgc
    12841 tgataaaatt cttcttcctg gggatcctct tcgtgctaag tttattgcgg agaatttcct
    12901 tgatgatgct gtttgtttta acgaagtgcg taacatgttt ggttacactg gtacttacaa
    12961 gggtcactgt gtatctgtca tgggaactgg gatgggaatg ccatctattt cgatttatgc
    13021 gcgtgagtta atcgtagact acggtgtgaa gaaattgatt cgtgtgggaa ctgcaggttc
    13081 tttgaatgaa gaggttcatg ttcgtgaatt agttttggcg caggcggctg caaccaactc
    13141 aaacatcgtt cgtaatgact ggccacagta cgattttcca caaattgcta gctttgattt
    13201 gcttgataaa gcctaccata tcgccaaaaa acttggtatg actactcacg ttgggaacgt
    13261 tttgtcatct gatgtctttt actcaaatta ctttgaaaag aatatcgagc ttggtaaatg
    13321 gggagtcaag gctgtggaaa tggaagcagc agctctttac tatcttgctg cccaatacca
    13381 tgttgatgcg ctagctatca tgaccatctc tgatagcttg gtcaatccag acgaagacac
    13441 aactgcagaa gaacgtcaaa ataccttcac tgatatgatg aaggttggtt tggaaacctt
    13501 gattgcagaa taattatagc caaaaaggaa gccctttatg aattgtagga cttccttttc
    13561 ttatccagaa attgatctag ctctctctga tttcgaagaa tagtgacttt atgtgaatat
    13621 tcttggcaaa gtttttggta attttctttt tgagttttgc tacgcccatc ccaaagaatc
    13681 catctgataa actcccactc aaagcgttca gggcaatctg ccgccatact ttctctgact
    13741 tttccacggt atttaagata acgcttaaag gctctaaaga gacaggtcaa tggcgaaaaa
    13801 ttgagaaaga tgatttggtc agcttcttgc attcgttctt ggtagtagca ccaagaataa
    13861 ttaccatcga tgacccaagc tttatgcttg gtgagaaagt tttttatctc ggttaacatc
    13921 cattcgcagt cactgtcttg ccaaccaggt tgaaattgga gtgtgtccat gtgcagtttt
    13981 ggaatggagt agtagttaga taacttttct gctatagttg acttaccaga accagaatat
    14041 ccgataattg cgattttcat tttctacttt ttcctatttg gagacaaaaa aacagcctct
    14101 atggactgtt tcttatttag caagtttagc tgaaagacga gctttatcgc ggcttgcttt
    14161 gtttttgtga atcaaacctt tagtttctgc tttatcgata gctgagctag cagcacggaa
    14221 aagttcttca gatgggtttg cttcgaaagc ttttatagca gtacgcatag ctgatttttg
    14281 agctgagttc ttttcgtttt gtttaacgtt caattcagcg cgtttgatag ctgatttaat
    14341 gtttgccaat gttcttacct ccatatttac taactatacc attatatatg aaaacttacg
    14401 ttttgacaag ggaaaattac ttttttaagt aaatttcatc gatttcatgg ttcttgcttt
    14461 tatgaagaat cacttctgca cgatttctgg ttggttcaat ataattttgc agatttgtga
    14521 gattgatact gatccagacc tgatgggcaa aggactccac ttccccaatc ggcatctgag
    14581 taaaacgata atagtagcta tcagggtcgt tttgggctag gctcagcatt ttcaagaaac
    14641 ggtccagata ccaactttca atatcatcca ctccagcatc tacatagatg gaaaagtcaa
    14701 agaagtcagt gatatagaga cgatcgtttt gtggattttg aaagacatta attccctcaa
    14761 caattacaaa atcagcagct ttgacacttt gtttcttttc gggtacgatg tcgtaaactt
    14821 catgagaata gacaggaata tctacatctt gtccattttt gatgcggtcc aagaagttga
    14881 gaagagcttc catatcatag ctttcaggaa atcctttacg atttaaaatc ccctgctcaa
    14941 tcaaggtttg attgggatag agaaaaccat cagttgtaac caactcaacc gtagcatctg
    15001 taaacgtacg ggacagtagg atttgaagta ggcgactggt tgtggatttt ccaacggcaa
    15061 cactcccaga aaccccaata ataaaaggtt gagatttact ttcacgttgg aggaaaattc
    15121 cttttgaaaa ggctaaatct tccttagttc gcttgtaaat ctgaatcaga tgagccaagg
    15181 ggagatagat atctgtaacg tcttggagac tgatttggtc attaaaactc ttgatagatt
    15241 ccaattcttc ttctgtcaaa ggaggtgttg tctttcgatg taaagattgc caagtctggc
    15301 ggctgatttt ttcaaaatgt aaaaattcgt tggtcatttg ttttccccta gatattttgt
    15361 ctatcatacc ataaaaagct aaaaaaataa agcggtttct tgaatgtggt aagtcaatgg
    15421 tatatagtat aagtgatcaa tttattgatg aaataggaga tagattctac tgatttataa
    15481 gcttataaag ggggcttttt agttcacaac ttataggagg tgtactatga aaatcttaaa
    15541 acgttacata ttggaactct gttttatttt aagttttgct ttacctttta taaaaggaac
    15601 caatgcagat aatggtagat gctttgtgga aacctattac ggttttactt ttttgatgga
    15661 acatgctatt gtaacagctg tctttatcta ttcgttttta attgctttct tactaaaaaa
    15721 acgatgggcg aaatggattg ctgctggtag ttattgcttt ttagtcctat ggattgcgac
    15781 agagggttat ttcttccgca tgtcactaga agatttgata cgactttgga caagtttgga
    15841 aatcctgaca caaacgtatc agttgggctt ttatctaaac attttgttag gaattttgtt
    15901 gataataaag tattttaagg ttaagcaata gaaataataa tctgcctgat tatagatgat
    15961 aaactttttg tttttatctg gactgtgata tttatagttc taaatggttt attatttata
    16021 agtgttgaaa gagattgaag aaaatggctt cgtgacttgc tttcttcggt ctttttcgtt
    16081 ttattatcaa tttgtaaacg atttacaatt tgagtcaaat tatggtaaaa tagtgtcatg
    16141 agtaaaatgt attatgcaga aaatcctgac gctgctcacg acattcatga gttgagagtg
    16201 gacttgttgg gacaaaaaat gacttttttg acagatgcgg gtgtttttag caagaaaatg
    16261 gttgactttg gaagtcaact cttgctcaag tgtctggatg tcaaccaagg agagacagtc
    16321 ctagatgtag gctgtggtta tggtccatta ggtttgtcct tggtcaaggt ttacggagtt
    16381 caggcgacca tggttgatat taacactcgt gccttggatt tagctcggag aaatgctgaa
    16441 aaaaataatg caaaagcgac gattttccag tccaacatct atgaacaagt tgaaggacat
    16501 tttgatcatg tcatttccaa tcctcctatc cgtgcgggca agcaagtcgt tcatgaaatc
    16561 attgagaaaa gtaaagattt cttggaaact ggtggggatt tgacaatcgt catccagaaa
    16621 aaacaagggg ctccaagtgc taagtccaag atggaggatg tgtttggtaa ttgtgaaatc
    16681 cttaaaaaag acaaaggata ctatatcctt agaagtgtga aagaatgaga gcagttgatt
    16741 taatacaaaa aaaacgagac ggtcaagaac tgacttcaag tgaaattgaa tggctggtag
    16801 aaggctatgt gtcaggaact gttcctgatt atcagatgtc tgcctttgct atggctgttt
    16861 attttaaagg aatgacgact cgtgaaattt ctgatttaac gatgaatatg gttaagactg
    16921 ggcaagagtt tgacctgtca gccattgatg gtgtgaaagt tgacaagcat tctactggtg
    16981 gtgtcggcga taaggtaacc ttgattttag ctcctcttgt tgctagcttc ggtgtgcctg
    17041 tagcaaaaat gagtggtcgt ggtcttggcc atacaggcgg aacaattgat aaattggagt
    17101 ccattagggg ctatcaagta gaacgtagtc aagaggattt tattcgtcag gttcaggata
    17161 ttggagtatc tgtcattggg caatcagacc agctggtcaa agcagataag cttctctatg
    17221 cccttcgtga tgtgaccgca actgtcgaca cgattccttt gattgcgagt tcggtgatga
    17281 gcaagaaaat tgcggcaggg gcggatgcta ttttgctaga cgtgactgtc ggtgagggtg
    17341 ccttcatgaa gacggttgat gaggcgcgtg agttggctca aactatggta gatcttggta
    17401 aggttgttgg acggaagaca gtagcagtga ttacggatat gagccagcct ttgggacgag
    17461 cgattggaaa tcgtctggaa atacttgaag cattggagat tttgcaaggt caaggacgtc
    17521 aggatattac ccactttatt tgtgaattgg ctcaaattat gcttggtttg gcaaatgtta
    17581 acaagactgt tgaagaagtt caccaacatc ttgagaatgg tcaagcactg gctaagtttg
    17641 aggaaatggt gcaagcccaa ggtggagact tggaagacct ctatcgtcct gtaaatgtag
    17701 ctcatgtggt ggaaatccct gctcaggaaa cgggtgtcat ttcagctctt ccagctatgg
    17761 actttggtct ttatgccatg aggctggggg ctggtcgtgc agttaagtct gatgccttgg
    17821 actatgaaac aggaattgtt tttgaaaaga agattggaga ctccgttcaa aagggtgaaa
    17881 ttgttgcaaa agtatacaca aatgaaaaaa ttccacctca actagttaca gatttccaaa
    17941 aatgtgttaa aataagtgat gaagtgaaaa aaatccgtga aattgtagaa atcatctcct
    18001 aaatggaggg aaaaccgaaa tgaaattaaa taaatatata gatcatacgc ttttaaaaca
    18061 agatgcaaag aaaaaacaaa ttgatagttt gttgtctgag gctagagagt atgactttgc
    18121 cagtgtttgc gttaatccga cctgggttga acatgctaaa aaaggacttg aaggcacaga
    18181 tgttaaggtt tgcacggtag taggtttccc tttgggagca acaacttcag ccgtgaaagc
    18241 atttgagaca aaagaagcta tccaaaatgg tgcagatgag attgatatgg tgatcaatgt
    18301 tggagctctc aaatcaggta atttagcctt ggttgagtca gatattcgcg cagtagtgga
    18361 agcaagtggt gataagttag tgaaagtcat tattgaagct tgccttctga cagaccaaga
    18421 aaaaattgtt gtttgccaat tggcccaaaa agctggggct gactttgtta aaacatctac
    18481 tggtttttca actggtggtg ctacgatagc agatgttaca ttaatgcgtg aaacagttgg
    18541 atctgatatg ggagtcaagg ctgctggtgg agctcgttct tatgcagatg ctcttgcctt
    18601 tgtcgaagca ggtgcgaccc gtatcggaac gtcagctggg gtagctattt taaaaggaga
    18661 attggcagat ggcgactact gagttgattg aactggcaat tgaaaccagc aaacatgcct
    18721 atgtccccta ttctcacttt cctatcggag cagttttagt agccaaagac ggaagtgttt
    18781 acacgggagt gaatatcgaa aatgctagct atcctttgac caattgcggt gagagaacag
    18841 ctatttttaa ggctatatct gaaggccaaa gagaattttc agaattgatt gtctatggtc
    18901 aaactgaaaa accgatctcg ccatgtggtg cttgtcgcca agtgatggct gaattttttg
    18961 aacaagatct aaaagtgacc ttagtcgcaa aagataaatc gacggtcgag atgacggtcg
    19021 gggaattact tccatactct tttacagact taaactagtc tgagtcgctc tctgagtggc
    19081 acggtccttg tggccaacca atccatactt gcaacatcgt tgcacatctt atttaggagg
    19141 ttcagtaatg aacaagaaac aatggctagg tcttggccta gttgcagtgg cagcagttgg
    19201 acttgctgca tgtggtaacc gctcttctcg taacgcagct tcatcttctg atgtgaagac
    19261 aaaagcagca atcgtcactg atactggtgg tgttgatgac aaatcattca accaatcagc
    19321 ttgggaaggt ttgcaggctt ggggtaaaga acacaatctt tcaaaagata acggtttcac
    19381 ttacttccaa tcaacaagtg aagctgacta cgctaacaac ttgcaacaag cggctggaag
    19441 ttacaaccta atcttcggtg ttggttttgc ccttaataat gcagttaaag atgcagcaaa
    19501 agaacacact gacttgaact atgtcttgat tgatgatgtg attaaagacc aaaagaatgt
    19561 tgcgagcgta actttcgctg ataatgagtc aggttacctt gcaggtgtgg ctgcagcaaa
    19621 aacaactaag acaaaacaag ttggttttgt aggtggtatc gaatctgaag ttatctctcg
    19681 ttttgaagca ggattcaagg ctggtgttgc gtcagtagac ccatctatca aagtccaagt
    19741 tgactacgct ggttcatttg gtgatgcggc taaaggtaaa acaattgcag ccgcacaata
    19801 cgcagccggt gcagatattg tttaccaagt agctggtggt acaggtgcag gtgtctttgc
    19861 agaggcaaaa tctctcaacg aaagccgtcc tgaaaatgaa aaagtttggg ttatcggtgt
    19921 tgatcgtgac caagaagcag aaggtaaata cacttctaaa gatggcaaag aatcaaactt
    19981 tgttcttgta tctactttga aacaagttgg tacaactgta aaagatattt ctaacaaggc
    20041 agaaaaagga gaattccctg gcggtcaagt gatcgtttac tcattgaagg ataaaggggt
    20101 tgacttggca gtaacaaacc tttcagaaga aggtaaaaaa gctgtcgaag atgcaaaagc
    20161 taaaatcctt gatggaagcg taaaagttcc tgaaaaataa tggatggaag tcatttctta
    20221 ggaagcggcc aagggccgct tttttaagag ttgagacaaa gtcattttgt ctcagtaaag
    20281 cttgctacta gacaaactag caagttttat tgaaataaaa taagactctg aaaggaagag
    20341 cacatggcac acgaaaatgt cattgagatg cgtgatatta ccaaggtgtt tggtggattt
    20401 gttgccaacg acaaaatcaa cttgcaccta cgaaaaggtg aaattcatgc acttttagga
    20461 gaaaatgggg ctggtaagtc cacgctaatg aacatgttag caggccttct tgaaccaact
    20521 agtggtgaaa tcgcggtcaa cggtcaagtt gtcaatctcg actccccatc taaagcagct
    20581 agcttgggaa tcgggatggt tcaccagcac tttatgttgg ttgaagcctt cacagtggct
    20641 gaaaacatca ttttaggtag tgaattgact aaaaatggtg tgctagatat cgctggagct
    20701 agcaaagaaa tcaaggctct ttctgaacgt tatggcttag ctgttgaccc ttctgccaag
    20761 gtagcagata tctcagttgg agcccaacaa cgtgtagaaa ttttaaaaac actttatcgg
    20821 ggggctgata tccttatctt tgacgaacca acggctgttt tgactccatc agaaattgat
    20881 gagttgatgg ctattatgaa aaatcttgtc aaagaaggaa aatcaattat cttgattacc
    20941 cacaaattgg atgaaattcg cgcagtttct gaccgtgtta cagttatccg tcgtgggaaa
    21001 tcaattgaaa ccgttgaaat tgcaggggct accaatgctg atttggcgga aatgatggta
    21061 ggacgttctg tttcctttaa aacagagaag caagcctcta aaccaaaaga agtggttttg
    21121 tctatcaaag atttggtggt caatgaaaac cgtggtgttc cagctgttaa aaatctgtcc
    21181 ttggatgttc gtgctggaga gattgttggt attgcgggga ttgatggaaa tggtcagtct
    21241 gaactgattc aagccattac aggtcttcgt aaggttgaat ctggtagcat tgagctaaaa
    21301 ggagattcaa ttgtaggctt gcacccacgt cagattacag aactaagtgt tgggcacgtt
    21361 ccagaagacc gtcaccgtga tggcttgatt ttggaaatga tgatatctga aaatattgcc
    21421 cttcaaacct actataaaga accacatagt aaaaatggaa ttttgaatta ttcaaatatt
    21481 acttcttatg ctaaaaagct gatggaagag tttgatgttc gcgctgccag tgaattagtt
    21541 cctgcagctg cactctcagg aggaaatcaa caaaaagcaa ttattgctcg tgaaattgat
    21601 cgagatcctg atctccttat cgttagccag ccaactcgtg ggttggatgt cggtgccatt
    21661 gagtatatcc acaaacgctt gattgaagag cgtgataatg gcaaggctgt ccttgttgtc
    21721 agctttgaat tggatgagat tttaaacgtc tcagaccgta ttgccgttat ccacgatggt
    21781 aagattcaag gtattgtatc accagaaaca accaataaac aagaacttgg tgtcttgatg
    21841 gctggtggaa acttgggaaa ggagaagagt gatgtctaaa aaattacaac aaatttcggt
    21901 tcccttgatt tctgtatttc taggaatttt actcggagcc attgtcatgt ggatcttcgg
    21961 ttatgatgct atttggggct acgaagaatt gttctataca gcctttggca gtctgcgtgg
    22021 gattggagaa atcttccgtg ctatgggtcc tctggtcttg attggtcttg gttttgcggt
    22081 tgccagtcga gctggtttct ttaacgtcgg acttcctggt caggctttgg caggttggat
    22141 tctcagtggt tggtttgcgc tgtcgcatcc agatatgccc cgtcccttga tgattctagc
    22201 aaccatcgtg attgccttga ttgctggtgg gattgtcgga gcgattccag gtattcttag
    22261 ggcctatcta gggacgtcag aggttattgt aaccatcatg atgaactaca ttgtcttgta
    22321 tgtagggaat gcctttatcc atgctttccc taaagacttc atgcaaagta cagattcgac
    22381 cattcgtgtt ggggctaatg caacctatca gacaccttgg ttggctgagt tgactggtaa
    22441 ctcacggatg aatattggta ttttctttgc catcattgcc gttgcagtta tttggttcat
    22501 gctcaagaaa acaactcttg gttttgaaat ccgtgcagtt ggtcttaatc cacatgcttc
    22561 agaatatgct ggtatttctg ccaagcggac tattatccta tctatgatta tttcaggtgc
    22621 cttggcaggt cttggtggag ctgttgaagg tttgggaacc ttccagaacg tctatgttca
    22681 aggttcgtca ttagctatcg gatttaacgg aatggcggtt agtttgcttg cggccaactc
    22741 accaattggt atactctttg cagccttcct atttggcgtt ctccaagttg gggctcctgg
    22801 tatgaatgcg gcgcaggtac catctgagct tgtcagcatt gtaacagcgt ctattatctt
    22861 ctttgtcagt gttcattacc ttatcgaacg ctttgtcaaa ccgaaaaaac aagttaaagg
    22921 aggtaagtaa agatgtctat tataaccttg ctccccctct tggtgtcttc tatgctgatt
    22981 tactcagcac ctctcatctt tacaagtatc ggtggtgttt tctctgaacg tggtggtgtg
    23041 gtaaacgttg gccttgaagg aattatggtt atgggtgcct tttctggagt tgtctttaac
    23101 cttgaatttg cagaacaatt tggagcagca actccatggc tatccttgct tgtagcagga
    23161 ttggttggta gtgttttctc tatcatccac gcagcagcga cggttcattt ccgtgcagac
    23221 catgttgtca gcggtacggt attgaacttg atggcgcctg ccttggctgt tttcttagtt
    23281 aaagttcttt ataacaaagg acaaaccgac aacctaagtc aaacttttgg acgctttgat
    23341 ttcccagtct tggcaaatat cccagtgatt ggtgatatct tcttcaagtc aactagtcta
    23401 cttggttatc tggcgattgc cttctcattc cttgcttggt ttattctctt taagactcaa
    23461 tttggtcttc gtctccgctc tgtcggtgaa catcctcaag cagcggatac cttgggaatc
    23521 aacgtctaca agatgagata tttagggatt attatttcag gttttctagg tggaattggc
    23581 ggagcgattt atgcgcaatc aatctcagtt aacttctcag tgacaactat tgttggacct
    23641 ggatttatcg cccttgctgc gatgatcttt gggaaatgga atccaatcgg tgctatgctt
    23701 tctagtctct tctttggact ttcacaaagt ttggctgtta tcggttctca attgccgttc
    23761 ctacaaggag tgccagcggt ttatcttcaa attgcacctt atgttttgac aattcttgtc
    23821 ttagcagcct tctttggaaa agcagtcgca ccaaaagcag atggtatcaa ctacatcaaa
    23881 tcaaaataag catacaaaaa aacgtcagtc caatgactga actgcccccc aaaagttaga
    23941 cagaaaaaat ctaacttttg gggtg
//
LOCUS       DAVBEM010000033        22296 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVBEM010000033 DAVBEM010000000
VERSION     DAVBEM010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22296
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.033"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(160..2118)
                     /gene="ftsH"
                     /locus_tag="VQ548_001351"
     CDS             complement(160..2118)
                     /gene="ftsH"
                     /locus_tag="VQ548_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HET2654196.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEETGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNREIHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(2134..2676)
                     /gene="hpt"
                     /locus_tag="VQ548_001352"
     CDS             complement(2134..2676)
                     /gene="hpt"
                     /locus_tag="VQ548_001352"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HET2654197.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2680..3957)
                     /gene="tilS"
                     /locus_tag="VQ548_001353"
     CDS             complement(2680..3957)
                     /gene="tilS"
                     /locus_tag="VQ548_001353"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HET2654198.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3954..5222)
                     /locus_tag="VQ548_001354"
     CDS             complement(3954..5222)
                     /locus_tag="VQ548_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HET2654199.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5342..5710)
                     /locus_tag="VQ548_001355"
     CDS             complement(5342..5710)
                     /locus_tag="VQ548_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HET2654200.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5703..5969)
                     /locus_tag="VQ548_001356"
     CDS             complement(5703..5969)
                     /locus_tag="VQ548_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HET2654201.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(6027..9536)
                     /gene="mfd"
                     /locus_tag="VQ548_001357"
     CDS             complement(6027..9536)
                     /gene="mfd"
                     /locus_tag="VQ548_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HET2654202.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYAQHAFIHQLKENG
                     YQKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPIQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            complement(9537..10106)
                     /locus_tag="VQ548_001358"
     CDS             complement(9537..10106)
                     /locus_tag="VQ548_001358"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HET2654203.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVKYYLQEKNFEKTMQRYNG"
     gene            complement(10177..11292)
                     /gene="ychF"
                     /locus_tag="VQ548_001359"
     CDS             complement(10177..11292)
                     /gene="ychF"
                     /locus_tag="VQ548_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HET2654204.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIIEFRFNV"
     gene            complement(11376..11570)
                     /locus_tag="VQ548_001360"
     CDS             complement(11376..11570)
                     /locus_tag="VQ548_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HET2654205.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11635..12771)
                     /gene="dnaN"
                     /locus_tag="VQ548_001361"
     CDS             complement(11635..12771)
                     /gene="dnaN"
                     /locus_tag="VQ548_001361"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HET2654206.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12930..14291)
                     /gene="dnaA"
                     /locus_tag="VQ548_001362"
     CDS             complement(12930..14291)
                     /gene="dnaA"
                     /locus_tag="VQ548_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HET2654207.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14504..15262)
                     /locus_tag="VQ548_001363"
     CDS             complement(14504..15262)
                     /locus_tag="VQ548_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HET2654208.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15320..16501)
                     /locus_tag="VQ548_001364"
     CDS             complement(15320..16501)
                     /locus_tag="VQ548_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET2654209.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16684..17163
                     /gene="rlmH"
                     /locus_tag="VQ548_001365"
     CDS             16684..17163
                     /gene="rlmH"
                     /locus_tag="VQ548_001365"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HET2654210.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17207..17280
                     /locus_tag="VQ548_001366"
     tRNA            17207..17280
                     /locus_tag="VQ548_001366"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17241..17243,aa:Arg,seq:tct)
     gene            17445..17570
                     /gene="comC"
                     /locus_tag="VQ548_001367"
     CDS             17445..17570
                     /gene="comC"
                     /locus_tag="VQ548_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HET2654211.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17591..18916
                     /locus_tag="VQ548_001368"
     CDS             17591..18916
                     /locus_tag="VQ548_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2654212.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18913..19665
                     /locus_tag="VQ548_001369"
     CDS             18913..19665
                     /locus_tag="VQ548_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2654213.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19717..19788
                     /locus_tag="VQ548_001370"
     tRNA            19717..19788
                     /locus_tag="VQ548_001370"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19750..19752,aa:Glu,seq:ttc)
     gene            19794..19867
                     /locus_tag="VQ548_001371"
     tRNA            19794..19867
                     /locus_tag="VQ548_001371"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19828..19830,aa:Asn,seq:gtt)
     gene            complement(19908..20450)
                     /locus_tag="VQ548_001372"
     CDS             complement(19908..20450)
                     /locus_tag="VQ548_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HET2654214.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20629..21396
                     /locus_tag="VQ548_001373"
     CDS             20629..21396
                     /locus_tag="VQ548_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HET2654215.1"
                     /translation="MIGISLIPDLYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            21481..22161
                     /locus_tag="VQ548_001374"
     CDS             21481..22161
                     /locus_tag="VQ548_001374"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HET2654216.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFVAAISTNMIFAKLPSGRH
                     PESRWAWLKSRAEINGIIAVLAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMV
                     TTLTTWNSRIGAFFLLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQT
                     ISINKSFS"
BASE COUNT         6894 a         4110 c         3641 g         7651 t
ORIGIN      
        1 acagtccctt ggacttcttc atacaattct ttaatcataa ttttcccctt tctagataca
       61 gtctaacaga ttagaaaaca catttgttcc attttctcca ttctgttccc tttagctcct
      121 aaactgcaca aaaaagagag gctccagcct ctctcagggt tatttttcgt cattcatttt
      181 tgactttact tcatcatagg atagtgcatg agattcctct tctactgctt caggcatctt
      241 tcctgtttcg taaagagctt taatttgtgt actatccaat gtttcgtatt tcaataatgc
      301 ttctgcaatt aacttgtgaa tttcacgatt tgactgaata atttcagcag ctttatttcg
      361 tgcctcattt aataatgaac gaacctcttc atcaatttca taagctgttt gttctgaaat
      421 tgatttttga ggactctgtg caccaaacat agcatggttt ccttcatatt gtactgggcc
      481 aagtttttca ctcataccgt actctgtaac cattgcacgc gccatttgtg tcgcttgttc
      541 aaagtcgttt gaagctcctg tagtttggac attaaagata atttcttcag ctacacgtcc
      601 acccattaag ccagccaatt gctctttcat atcttcttta gatagaagca tttgatcctc
      661 tttaggaagt gcaatcatgt atccgcctgc acggccgcgt ggtacaattg taaccttatg
      721 gacaacgcga gcattcgaca agactagacc aacaatggta tgtcctgcct catggtaagc
      781 aaccaattct cgttcttttt gtgaaactgt cttatctttc ttagaaggtc cagcaataac
      841 tctatcttct gcttcatcaa tatctgaagc atcaattatc gatttattgc gacgagcagc
      901 aactaaagct gcttcattca agacattctc taaatcagca ccaacaaagc ctggagtttg
      961 ttgagccact aatttcaaat caacatcttc tgctaaaggc ttgttcttag cgtgaacttt
     1021 caagattgct tcacgacctt taacatcagg acgaccaacc aatacttttc tatcaaaacg
     1081 tcctggacgc aaaagggcag gatcaagtac atctgaacgg tttgtcgcag cgatgacgat
     1141 aatcccttca tttccctcaa aaccatccat ctcaatcaaa agttggttca aggtttgttc
     1201 acgttcgtca ttacctccgc cgagaccgac tccacgttga cgtccaacag catcaatttc
     1261 atcgataaag atgatagctg gtgctgcttt tttggcatcc tcaaaaagag agcgaacacg
     1321 actagctcca actccgacaa acatttctac aaagtcagaa cctgagatac taaagaatgg
     1381 aacacctgct tctccagcga ctgccttagc aagcaaagtt ttacctgtcc ccggaggtcc
     1441 ctccaaaaga acacctgctg gaatacgggc tccaagtttt gtgaatcgtt ttggatcttt
     1501 taagaactca acaacttcaa ctagttcttg tttttcttcc tcagctccag caacatctga
     1561 aaatcttact ttaatatctt ctttatttgc tgctttagcc ttactacgtc caaaactcat
     1621 tggattacgg ccattgcctc ctcccatatt tcccatcata gagaatagga agaagaatag
     1681 aattccaaat ggcacaatgg atacgagtag attaatccat ataccacttg aactttcatg
     1741 cttaacagtt acttctgctt tatggtcagt agcaagtttt tgcaattctg atacggtagt
     1801 atctgcagga agaatagtgc tggtaaattt ctctacctta gtaacagatg gcgtgaaaaa
     1861 ctgaatacct gtttcttctt tacttgtttt aggattttta tagacaccag aaacttcgat
     1921 aacactacca tttggttggt aagttaattc ttttacatta ccatcggtaa tttcttgtac
     1981 caactcagta tagttgattt gctgacttcc tcctgagtta ttcccagaat agaaatactg
     2041 gaatcctgtc acaaggaaaa agataaataa taaccataga aaaggatttt taattaaacc
     2101 attattttgt tttttcatta aagattattc tttctaattt gaatacactt cctctttcaa
     2161 tactccaata taaggaagat tacgataatt ttctttgtag tctaaaccat aacctactac
     2221 aaactcattt gggatagtaa agcaggtata gtctgcctca atttctacaa cacgtccttc
     2281 tggtttatcc aacaaggttg caattttaac agaagctgct tctcttgctt taaacatatc
     2341 tcgcaaattc ttcaaagttt gacctgtatc aatgatatct tctacaaata gaacatgtct
     2401 tcctttgata tcttgagtca catcttgttt aatattgata acaccactac ttgctgttcc
     2461 accatggtag ctagaaacca tcatgaagtc catttcaata tgtgtatcaa tatgtttgac
     2521 caattcagcc ataaaaggaa tagatccttt taaaatccca actaagattg gattttttcc
     2581 tgcatagtct ttagttaatt gagcacctag ttttttagct gcttctgtaa tttcatcgtg
     2641 tgaaacgagg acttttttaa tatcgttttc taacattttt tacctatcta ttttttctat
     2701 ataaagtaca gtgttcatta tatcattttt cgttttttta ctcaaattat tggtcgcaat
     2761 tcccaaaatt gagacaattt caccaaattg ctcaataata agagcagagt ttctcttttc
     2821 catagggatt ttcaaatcaa taaataaacg tctgagtttt tttctatgcc cattttgaat
     2881 caaaacatct cctgtttttc gatgacgaat gtgtatggat gtttcacgtg aaacaggtat
     2941 ttgttgaatt gattcacctt ctaatggaag tccaaaggaa aataaatatc cttgataagc
     3001 tacctgattt tgatagtgta acacaagttc atcttcctct tcatcagcct gcggactgat
     3061 tttacaaatc tgaaactgtt ggtactcttt tatcaattca tagccatttt taatcggatg
     3121 acgatactgg cttttagatt ttaaaatctg ctgaacttca gcaaactgag cttttgtaag
     3181 attcaaatct ggaaaacgat tcagataagt ttgaagtaaa actctttgtg tagactcaga
     3241 gtaagaaaat aactgctgta aatcttccac attaatattg ttagataatt cagctattgc
     3301 caaatcataa tctaaaattt cattgccaat gcctaagatt gcatccctaa atcgaggatt
     3361 ttctttttcc aattctggta agtaagagtt tcgaatacga tttcgaaaat aatgattctc
     3421 ctgatttgat gtatcttcaa agtgaaaaat tgatggaaag tcttttttct gaaaatgcaa
     3481 gaagggacga atgatttcta tctctccgac tacttgcttc tccttaattc ctgatagata
     3541 gcgcaagcga gttcctcgaa tcaagcgcat caaaatcgtt tccacctgat catcagcatg
     3601 gtgggcagtg actaaagctg tcgcacctgt ctttttcatg acctcttgaa aaaaatcata
     3661 acgaaaattt cgtgcacgcg cttctgaaaa ttctcctgaa aaattgctga tataaatagg
     3721 aagctctgct tcagcagcca acttccttaa ttccttttct tcccaatctg attcaattct
     3781 ctgcttatga ttcacatgag ctagaatcaa ttcaatctct aactcttttt gataagtaga
     3841 caatacctta aatagaaaca tggaatctaa tccaccagaa agagctagaa ccgccttagc
     3901 atgctttttg aaatatccct tcttgagaaa atgatttaaa aaatctggtt ccctcatttt
     3961 agaacctcat aaacatcctt ggctatctta gaaatcgtat cataatcaga attcttagtg
     4021 aaaatagaaa gaataaatgg agaatctgca tagacaacac ccgtatcatg cttaaattca
     4081 tccgcatctc caattttatg agctacttta acagaaacac ctttggcaat tcgctgacta
     4141 tcaaaatctg ttttagtcaa agactctaac acaaatccat tttgattata aatagcttcc
     4201 ataaacttcc cggccatctt agaagaaatc aatttttctt ttggatccca atcatctccc
     4261 ataatggcag acatcttgga tttgaatgtg gcatcagatt ggtttgaaat gtaatatccc
     4321 aatagattat gagctacatt atcagattct tttgatactt tcgtaattaa atcctttaaa
     4381 gaatattctt tattatcttc ttttttagga agactaccac ttccctctgg tttataagaa
     4441 cctggaaaat cattgactgc agatacgtat tttacagtcg tatctaactg ataaagaccc
     4501 tcatttattt tttcttgcgt ataatagaga taagagagtt tcaaaacgct ggctgcatac
     4561 atcttttcat cttgattgat accagcttct tttccagtag tcagttgctt aacataaata
     4621 gagaaagaat ctttctgata tttttcagat aacatttctt gaactttact catccgatta
     4681 tcttcttcag aagttgattc tttagctacc catccagcct gatcaatatg tagaaattct
     4741 cttccttcta caaacatggt cttgtcgatt gatacttgcg aataagctga taaggatgat
     4801 ttcacttctt ttaaatcata aggactattg tacagtttaa agtcagattc taaccatgct
     4861 ttttttattg ttggagttac ctctgattga tcatataaaa atcgtttgtc cgcagctata
     4921 aattgatgat ttgatagctt aaatactgga attccttgtt tatttaagcg ccactcggtt
     4981 atttgaaaac ttgttttggg agtcaatttc ccagattcca ctactaaatc ttcattcgca
     5041 taaacaggaa cctctccata aaccatggga gaacttaatt tttctctaaa ataaatacca
     5101 aagtcagatt gtgaaaggta ataaatttct ttcgaagtat agacgacttc tttttctgtg
     5161 ctaacgactt ttgaaatggt caaaaaactt ggtagcaaca aaataattaa gaatttacgc
     5221 attcttcctt tccttttctt cttgtaaacg caataattga tttttatcag ccaattcttc
     5281 cagcttttca tctgacaaac tcaaaaattg ctctattacg tctaataaat tttccatttt
     5341 atcacctttg aagcaagtca ggaatcgtat aaactttttc cctcgactta gaataatagt
     5401 acttcgctcg tgtatatttg gcagcataat cttcatcttt caacttggta gcaaatgctg
     5461 tctccttatc cttttcatca ctcaaagttt gatactgagt ttgcaagtct gctaattgct
     5521 gacgtctttg gagtaattgc tgataactct gcgctaaatt aaaagttggc aagataaata
     5581 atagcataat caaaatcaat acccctccca taaaacgatt ccgtttttgt cgttctttca
     5641 tcaggtagcg acgacgttgg tattcatttt gaataaaaga attattcaat tgtacaatat
     5701 ttttagacat tttcttctac ccgtgtttca ctgataattt catacattcc tgctgcatct
     5761 tctttttttg tactatcttt catctctagt acttttacaa gcagcaactt attgccaaag
     5821 cgaatttcaa cttggtcatt aactttcaag tccgttgaac ttttggccaa gattccatta
     5881 accttgattc tacctttatc tgctacttcc tttgcgactg tacgacgctt gataattcgc
     5941 gatactttta aatatttatc taatctcatc cttattacct caatttatta ttgtaccatt
     6001 tttatctatt ttatagaaga aaaatatcaa atggaatttt cttccttaaa ctcttttatc
     6061 tctaataaac tttctccaaa aatcagcaga ccttctaaaa tttcataatc tttcttattt
     6121 tggacatcaa atacaagctc cattaatccc ttattctcag cgatgcctgc ttttaagttc
     6181 gttacggata aagctttaaa ataatcttga gctaaaaaca atcgttgagt gactttttca
     6241 aattgaattg taattttatt atcttttctt tccacacgtt gaacaaagac cttgtccaag
     6301 tatgatttaa ccaaaccaat ctctaaaaga taggctacta catctgggta ttctccaaaa
     6361 cggtctatca actcctcttg taactcttca taattgacac ggttgtcaat ttgacgaatt
     6421 ttcttgtaaa tttcaatctt atgtcgttga tcagaaatat aagtatcagg aagataggca
     6481 tcaatttgca aaatcaactc agcattccct ttggttcttg tgttagcgtt agcattaccg
     6541 tttcgtttag caatagcttc ctctaataac tgcgaataca attcaaaacc aacagaatca
     6601 atgaaaccag actgggattt tcctaaaaga tttcctgctc cacgaatcga aagatctcgc
     6661 attgcaatct taaagccaga gcccaattct gtaaatcctt taatcgcttc taatctcttt
     6721 tcagagactt cactgattga tttttctgga cgatacatga gataagcata agcaatacga
     6781 ttactacgac cgactcttcc tcttaactga tataaggttg acaagcccat atggtccgca
     6841 ttttcaataa ataaagtatt agcatttgga atgtccaccc ctgtctcaat aatagtagtc
     6901 gtcaccaaga tatcgtattg tccctcaata aagtctaata gagtattttc caactggact
     6961 tcactcattc gaccatgaac atatccaatc gaagcctccg gaatcaactc ctgtaattct
     7021 gaaaccttct gaacaattgt gtcaactttg ttgtaaagat aataaacttg acctccacgc
     7081 tccatttcac gcaagacagc atcacgaatg acactatcat tcttttccaa aacataggtc
     7141 tgaacaggat agcgattagt cggcggagtt tcaataacag ataaatctct gattcccagc
     7201 atagacatat ggagggtacg agggattggc gtagcggtca aggttaggac atccacttgt
     7261 ttcttcagtt ctttcaaagt ttccttatgc ttgacaccaa atcgctgttc ctcatcaata
     7321 atcatcaagc ccaaatcagc aaacacaaca tcttttgaca aaacacgatg tgttccaatc
     7381 aaaatatcga cttgaccgtt tttcaatttt tcaagtgttg cagtctgctc ttttttactt
     7441 ctaaagcgac tcaacacatc aatattaact gcaaaatttt ggaatcgttc cttaaaattc
     7501 gtatagtgct gttgcgctaa aaccgtcgtc ggaactagaa tgacaacctg tttgtgatca
     7561 ttgactgctt taaaggctgc acgcatagca acttcagtct ttccaaaacc aacatcccca
     7621 actaaaagtc gatccattgg ctgagaagcc tgcatatccc tcttgatttc ctcaatacta
     7681 cgaagttgat catccgtttc aacataaggg aaagcatcat caaaggcatc ttgatcatca
     7741 tcatcagctg agaaagcaaa acccttcaac tgactacgtt cagagtagag tttgattaaa
     7801 tcatcagcta tatcctctac ctggttctta accttttgct tggccttttt aaaatgaccg
     7861 tcatttaatt tattgagttt tggagcttta ccatcacttg aaatatattt ggacagtaga
     7921 tgaatctgtt ccacggggat agaaatttga tcaccatttt ggtattggac actgacataa
     7981 tcgcgatgaa ttcccttgat ttcaatggtt tcaattccta gatattgacc aatcccatgg
     8041 atatgatgga caacatagtc ccctttttca agttcattgt aatcttttaa tctctctgca
     8101 tttgaaacat gttgtcttcg aaaacgacgc tttaatttct tttgaaaaat ctcatgttca
     8161 gttatcaata aaatcttttc atctacaaaa tgaaaaccat gtctgagatt accctctatt
     8221 aaatttacag attctttaca gatacttgtc ttatctctag aatccaattt aatctgatat
     8281 tcctctaaca tatcctccaa tgttttactt cccattgaat tgctagactg cagaataatg
     8341 gtgtaatcca tttttttata tcgttcaatt tcttctttta gaaaagaaaa ctgattgaaa
     8401 aattcctgta taggatattg attgaattga taaattttgt caaatttgag atttcctaaa
     8461 cccttttgaa gattagagaa aaaggtcact ggactttgtt ttttatagat ttgttcaata
     8521 tcagaaaaat actgcatatc agaaaatgct ttactattct gtaattcttc tgtaaagtac
     8581 tgcgctaatt ctctttcaaa gacttcatac tgattcatca atttttgata atcatcaaag
     8641 aatattggag tatctttttc aatataatca aagacagtcc atgtcttatc atagcacaaa
     8701 gataaaaact tccgagaatc tgcatgactt tgtttttggt gaaaacttga aagaatttct
     8761 tctaggtatg atttcaaaat aggtgataaa gtttttgaaa tttgtttttc taaagctgac
     8821 tgtcctcgtt gataatcctt ttctctcaaa agcatatcac tagctggaaa gatagtgagt
     8881 tctgtcttat tttctttcga taattgtgtt tctacttcaa atgacctgat accatcaatt
     8941 tcatcaccaa aaaactcaat tcgacaaggt tctaactggg atatttcaaa aatatctaaa
     9001 atatctcctc gaagactaaa ttcgccctga gtttgtactt gagtaacttt ttgatagcca
     9061 ttttccttta actgatggat aaacgcgtgt tgagcatatt cttcaccaac tgagattttt
     9121 acaatactat ctttgaatgc attgggagac ggtaaaatca atcgacttgc tgcgatatta
     9181 caaactaaaa tccctttctt agatgaatca gtcaaaaaac gcaaggcttc aacccgtgaa
     9241 ataatttttt cctgtgaaga catcaaaaac tccaccatag gagcatcatc taccaaaaat
     9301 ggatagacga gttcctcacc caagatagaa ataagatcac taacaagtcc ttctgcttct
     9361 ccataagttg acgtcaataa cacaatccta tcttcttttt ctaaactgct tgcaattgca
     9421 agagccttag tagatgttga taaaccaagt attagttgtc ttttcttatc tgttaaattt
     9481 tgatgccatt ttttaatctg atcattttct gagaataaat ctaataaggt caccatttat
     9541 ccgttatacc tctgcattgt tttctcaaaa tttttctctt gtaaatagta ttttacagaa
     9601 tcgtcaactt tgtcaacaga ctgtaaaata ccgatataat catccctgtc aaacttactc
     9661 aaaacatgat gaacaactga cataccattt ttaggtcttc caattccaat cttaacacgg
     9721 ttaaagacct gagttcctat atgttgaata atagacttga taccattatg accacctgct
     9781 gagccttttg ctcttaaacg aattttccca acttccatgt caagatcatc gtaaatgata
     9841 agtaaatcgt caatatccaa accatagtaa gttaataaag catgaactgc ttttccactt
     9901 tcattcataa aggtcgttgg tttaaccaga taaatttttt ctccatttag gaaaaaggat
     9961 gctaggtcag cttgaaatat cttatcgtgt gtaaaagtga cattctgttt cttcgctagt
    10021 tgatcaatca acataaaacc aacattgtgt tttgtttcaa aatatttatc ccctggattt
    10081 cccaaaccta caagtaattt ggtcatttat ttttcctttc aaaagccaaa agggttggaa
    10141 tttttttcca acctaattga caccatttat taatttttag acattaaagc ggaattctat
    10201 gatgtcgcca tcttgaacga tatattcttt tccttcttca cgcaagcgtc cagcttcttt
    10261 tacggccttt tcagatccgt atttcactag atcttcatat gacatggtta ctgcacgaat
    10321 aaagcctttt tcaaagtctg agtggataat accagctgct tgaggagcct tcataccacg
    10381 tttgaaagtc caagcgcgaa cttctttttc accagctgtg aagtaagttc ccaatccaag
    10441 caagtggtaa gctgcacgcg tcaacttatc tacacctgat tctgtcaaac caatggcttc
    10501 aagaaactct tttttatctt catcatccaa ttcagaaatt tcttcctcag cacgcgcaga
    10561 aataacgact acttcagcat tttctgtcgc tgcaaattca cgaatttgtt tgacatagtc
    10621 gatagagtca ggttctgaaa ccacatcctc gtccacatta gctacataaa gaactggttt
    10681 agtcgtcaaa aggaaaagac ctttgacaac cttttgttcc tcatctgtaa attcaatggt
    10741 acgagctgat ttcccgtctt ctaggactgg tttaatcttt tgaagaacat tgaattctgc
    10801 tactgattct ttatcttttt gcgtacgtgc catcttttct acacgcgcat atcgtttgtt
    10861 cactgattct aagtcagcaa gaattaattc cagattaatt gtatcaatat ctgcaagtgg
    10921 atctacaaag gcgtcttcac gtccttgctc gcgcatcaca ttttcatcat caaaagcacg
    10981 aactacgtga acaatcgcat ctacttcacg aatattggcc aagaatttat tccctagccc
    11041 ttctcctttt gaagctcctt ttacaatccc tgcaatatcc gtaaattcaa atgttgtggg
    11101 aactgtcttt ttaggagtta tcatttcagt tagtttttgt aggcgttcat ctggaacttc
    11161 caccattcca acatttggat caatcgtcgc aaatgggtag tttgctgcct ctgctcctgc
    11221 ttttgtaatt gcattaaata gtgttgattt accaacgttt ggcaaaccaa cgatacctgc
    11281 tgtcaaagcc atatttctca ttctccgttt tcatttcaat ccctaatatt ataacacaaa
    11341 aagggataaa gtgctaaccc tctaactaag ggttctcagt caataatttt attcattttt
    11401 cgctcaaaat catatcgccc catcatgaca acatgctcac aattactgca ttttattttg
    11461 atatctgctc ctacacgtgt aatttcccaa cgattagcct ttttaccagt cgacttgatt
    11521 gtacaagcgt gtgatttttt catctcaaca aaatttccaa cttgatacat actactctcc
    11581 ttttcttttt cgattatatc ataaaagagg cgagccaggc tcaacctctt tcacttaatt
    11641 tgtacgaact ggtgtaatga gctgcatgaa gtcttcgtca gtatctgctg gcacaagagt
    11701 aaatggacga acagctgaga taaagctaat ggtcaccttt tcgctattta aagctttaag
    11761 agaatcaatc aagtaagttg ggttgaaact aatggtcaaa tcttcaccag taacctgatc
    11821 agtatcgatt tcttcgttta ctttaccaac ttctggagag tgaacatggg cgctaacaac
    11881 cccatcctta atttcaagtt tcacagtacc attttgagtc gcacttgata aaagacgggc
    11941 acgctccatt gactggcgta agtttaccac attaaaagta atagtagtgt taaagtctgt
    12001 tggaatcaag cgatctgtat caggatagtt tccttctagg agacgagtat agaagctaat
    12061 attttcgctt ctaaagagga tttggttatt ggcaaagaaa atctctacag tttcgatatc
    12121 atctgtaaat accgctgaaa attcgcgtag agaacggcta ggaattacga catcaaaatc
    12181 atcactattt ttttcaagag tcaatttttt ctggcttagg cgatgagagt ctgttgcaac
    12241 tgtttttaac tctttgtgtt gactcaatac gaagtggaca cctgttaaaa tcggacgact
    12301 ctcttgtgta cttgcagcaa aggctgtttc attaataatt ttcttgagta attttgtttc
    12361 aagtattaaa ggagtgcttg ctgaaatttc ttggattcgt ggatattgtt cgctatcttt
    12421 tccttttagg gtaatttctg atttgccact ggttaaaaca atttgatttt gttcaatttc
    12481 tttaaaatca agagttacat caggtaaact agatactaca ttgataaaga aagaagcttc
    12541 aagaaggatc gaacctaaag aagtaattaa caaaccagca tcttcatttt tttgagaaat
    12601 aaaattttca attgaaattt gaccatttga accaattaaa gtaatacctt cattggtcac
    12661 gtcaattttt actgttgata aaataggaat ggcattttta gaactaatag ctctcttagt
    12721 agtatttaat gcttgtagaa ataaattttt attaattgaa aaatgaatca tggattctcc
    12781 tttatttatt tttagtatta gaaagataat agtaataata gagtctgtga aatctgtgga
    12841 aaacagcctt taaacaagtc atatcaagtt ttttagcttg tttaaaaaat gtggataaaa
    12901 aagataaaaa actaaaagtt atccacaaat tatttgattt tctttttgat tgattcaatt
    12961 tctaaacgta aattatcgtc ttgatcaatc aaagatttta ttttggcatg ggcatgaatg
    13021 actgtggtat gatcttttcc cccaaattcc ttcccaattt ttggaagact attatctgtt
    13081 agttctctag ataaatacat ggctacttga cgggccaaaa caatattttg aaggcgtcta
    13141 cttcccttca tttctttgat actaacacca taaaagttac caacttcagt ttggatttta
    13201 tcaattggga tgacgagcat ttggctaaca tcttgtttgc gggctctaat ggcttctgca
    13261 gcaatatcaa tagtgatatc cttgattttt tttactctgg caattaaagt gatgtcgttg
    13321 atggctccct caagatctcg aacatttgaa tcaaattgcc cagctaggta ttctagagta
    13381 tcactttgga aattgtagcc taaatgttcc gttttacttt gtaaaatggc aatacgtgtt
    13441 tcaaagtcag ggggtgtgat agtttgtgtc aatccccaac taaaacgcgt gacaagcctc
    13501 tcctcgagcc cttctagatg ttttggacta cgatcactcg ttaggacaat ctgtttttgc
    13561 ttgtcatgaa gggcgttaaa ggtattgaaa aattcttcct gagttgcgac tttttttccg
    13621 ctgagtgact ggatatcatc gattaacaaa agatcaagac tacgataggt ctttttaaac
    13681 ttttccattt ccccaagtct taggtgatca agaaagtcat taataaagct ttcggcaggg
    13741 atatatttaa cacgcgcatt aggaatattt tttagaattt catttccaat agcgtttaat
    13801 aagtgagtct taccaaggcc tggtcctcca tagataaaaa gagggttata ggtcagagcc
    13861 aaatcttcag agacagctaa agcggctgac acagcccaaa catttccatc cccttgaata
    13921 aagttatcaa aggtatactt ttcttttaat cccgtatctg aataaggaat agatactaac
    13981 tttggactat agttataaag agttaaattt gtagcttctt caacttgtga gctagtcgta
    14041 tcttgaggtt tggtgaaaat atagtgggga gttatttcag cgtcataaat ttcaaaacca
    14101 gctactacaa taatatcttt tagttgtttt tcccagacca tttccatttc agagcgaggt
    14161 agaaatatag tggcaacatt ttcctctacc ttgatgagtt cagcttgaat agcatagaaa
    14221 tcatacatgg atcgagtcag tctttcttgt gcaaattcta atatacgatt ccaaaattgt
    14281 ttttctttca atcctttctc ctcctttact atttaaaagt ttaatactag agatatttta
    14341 ccatagatag caagaatttt ccacaagctg tgaaaaataa tccacaatgt taccaaactt
    14401 tatccacagg ttggggataa aagaagaaat tattgattta ttaagctttt tattgaaaaa
    14461 catagtggat aaccttgtga gataaaaaaa taaaagaaca gccttatttc aggctgttga
    14521 taattctact atattcttct tgatttgaaa aagaaataat gatttttcca ctgtcttttt
    14581 tagatagttt aatttctaca tctaatccga gtagttttct taactgtttt tcttcatttt
    14641 gtatgaaatg attagttttt tgctgtttct tttgtttttt ctctgtcaga agagcttcta
    14701 atttccttac agaaatatct tcttctataa tccgttgaaa gaaatagtct tgttgttcct
    14761 tatttaaccc aactagggaa cgcgcatggg cttgtgatag tttgccattt tctacttctg
    14821 aaagaatctg ttctggcaag gaaagtaaac gaatggagtt gctgatatat ggacgagact
    14881 tgcccatctt atctgcaatt tcagcatggg tgaatccttt ctctacgaga gattcatagg
    14941 cgcgtgcttc ttctattggg tttaaatttt ctctctgtaa attttcaata atggactgga
    15001 ccatcatctc ttggtctgaa atctgtttaa caacagctgg gatagaccgt agaccagcta
    15061 aaagtgaagc ccgatagcgt ctctctcctg caaggatttc ataaccaata acaggagatt
    15121 gacgaacaat aatcggttga atgaccccat tttctttgat agactgtgct agttcatcta
    15181 gtttttctct atcaaattct tttcggggtt gatagggatt tttttgtata tctgtgatag
    15241 aaatcatttc aaatttttcc atgattctac actaacacat cttttctctt atgtaaagct
    15301 ttctttacat agatgtcaat taagattcta aatcacctga actcttgtta agtttgatag
    15361 aggtagtttc ttctttcccg ttacgatagt aggttatctt aatggtgtct ccgatagaat
    15421 ggttgtaaag agcactttgt aagtctgttg atgaagcaat ctctttgtca tctacttttg
    15481 taattacatc gtatttttca aggtgaccat tggcaggcat attactttgt accgaacgaa
    15541 caactacacc agatgtaaca ttacttggaa tattgagtct tctgatgtcg cttgtactca
    15601 cattagataa attaaccatc tggattccca aagctggacg cgtcactttt ccgttttttt
    15661 ctaactgttc aataatattg atagcatcat ttgcaggaat tgcgaaacca agaccttcta
    15721 cagatgttcc tccatttgta gcaattttac ttgaggtaat tccgataacc tgcccttgaa
    15781 tattgatcag tgggccgcca gagttacctg ggttaatagc agtatcagtt tggatggctt
    15841 ttgtagaaat agcttgtcca tcttccgatt ttaaggatac atttctattg agactggata
    15901 cgataccttg agtgacagta tttgcatatt cagaacctaa cgggctaccg atggcaatag
    15961 cagtttctcc tacagttaac ttactagaat caccaaactc agctactgtt gtcacttttt
    16021 ctgaagagat ttttacgaca gcaatatcag agaaagtgtc agctccgaca atttctccag
    16081 gtactttagt cccatctgac aatcgaatat ctactttgct ggcgccattt ataacgtgat
    16141 tgttggtgac gatgtaagct tctttatcat tctttttata aataactcca gatccttcac
    16201 tagagattcg ctgagaatct gtgtcagtat catcattgcc aaatacgcta ttttgtctgt
    16261 ttgccgaata agtaataaca gaaacaacag catcttttac tttgttaaca gcctgtgttg
    16321 ttgaattttc gttcttatag gcagtttgtg taatagtact attgttgtta gagttgttta
    16381 cactactttt ttgagttagt tgagttattg aaaaactacc caaggctcca ctaaaaaagc
    16441 taatgacgat aacgactaat aattgaaacc attttttgta aaatgttttt agatgtttca
    16501 tatttgcctc catatgtttg aattactgaa agtataaact gactagctta attataactt
    16561 aaacacaaaa gttttacaca aactgtggat aactcttttg aaactgtgat tttcttaatt
    16621 gaaatctatt ttttattttg tgaataagat gtgaaaaaat agagaatatg ttagaataga
    16681 gtcatgaaaa ttaaagttgt aacagttggg aaactgaaag aaaagtattt aaaagatggt
    16741 atcgcagagt attcaaaacg aatttctaga tttgctaagt ttgaaatgat tgagttatca
    16801 gatgaaaaaa caccagataa ggccagtgaa tcagaaaatc aaaagatttt agaaatagaa
    16861 ggtcagagaa ttttatcaaa aattgctgac cgtgatttcg ttattgtgtt agccattgaa
    16921 gggaaaactt tcttctcaga agaatttagt aagcagttag aagaaacttc tataaaagga
    16981 ttttctactc ttacttttat tattggggga agtttaggat tgtcatcatc tgtaaaaaat
    17041 agagccaatc tttctgtcag ttttggtcgc ctaaccttac cccatcagtt aatgagacta
    17101 gttcttgttg aacaaatcta tcgcgctttt acgattcagc agggattccc ctaccataaa
    17161 tagaaaattg acttttaatt gaatttttgg tagaataatt gtattaggtc tcatagctca
    17221 gctggataga gcattcgcct tctaagcgaa cggtcgcagg ttcgaatcct gctgggatca
    17281 atataatagc aaagctggga attttcccgg cttttttctt aaaaaagtac actttgggag
    17341 aaaaaaatga cagttgagag aattttatct aaaacgaaat tccattttgt ataatggttt
    17401 ttgtaagtta gcttacaaga aaaaacattt taggagattt tattatgaaa aacacagtta
    17461 aattggaaca gtttgtagct ttgaaggaaa aagacttaca aaagattaaa ggtggggaga
    17521 tgaggttgtc aaaattcttc cgtgatttta ttttacaaag aaaaaagtaa tgaaataagg
    17581 ggaaagagta atggatttat ttggatttgg gacggttatt gttcattttt taattattag
    17641 tcacagttac cattttattt gtaaaggtca aataaataga aaagaattat tcgtttttgg
    17701 tgcttataca ttactaacag aaatagtatt tgattttccc ttatatattc tatatttaga
    17761 tgggttaggg attgaaagat ttttatttcc tttgggatta tattcctatt ttcgatggat
    17821 gaaacagtat gagagggata gaggactatt cctaagttta ctactatctc ttttatatga
    17881 gagcactcat aactttctgt ccgtaacttt ctcctctata acaggagata attttgtttt
    17941 acaatatcat ttcccattct ttttcgttgt gacggtgtta acctattttg ttacattaaa
    18001 aatcatttac tatttccatt tggaactagc ctattttgac gaggactacc tttatccttt
    18061 cttgaaaaaa gtattttttg ctttactatt gctacatatt gtatctttcg tttcagatat
    18121 ggtaagtacg attaaacatt tgaatagttt tggaagtatt ttgtcatcta ttgtctttat
    18181 ctctctcctt ttgaccttct ttgcaatgaa ttctcataaa gttcaaatgg agaaagagat
    18241 tgctttgaag cagaagaaat ttgaacagaa acatttacag aattacacag atgaaattgt
    18301 tggtctgtat aatgaaatcc gtggttttcg acatgattat gctggaatgc ttgtcagcat
    18361 gcagatggca attgacagtg gtaatttaca ggaaattgac agaatttaca atgaagtttt
    18421 agtcaaagca aatcataaat tgcgttcaga taagtacact tactttgatt tgaacaacat
    18481 agaagactca gctttacgaa gtttggttgc tcagtcaatt gtctatgctc gaaataatgg
    18541 tgtagagttt acactggaag taaaagatac gattaccaag cttccaattg aactattgga
    18601 tttggttcgt atcatgagcg ttttattgaa taatgctgtc gaaggatcgg ctgatagcta
    18661 taaaaagcag atggaagtag cagttattaa gatggaaact gaaacagtta ttgtgattca
    18721 gaattcatgt aaaatgacga tgactccttc aggagatcta tttgccttag gattctccac
    18781 taagggaaga aatcgcggag tcggattaaa taatgtgaaa gaactactag ataagtacaa
    18841 caatattatt ttagaaacag agatggaagg cagtacattt agacaaatca ttagatttaa
    18901 gagggaattt gaatgaaagt tttaatttta gaagatgtta ttgaacatca agtgagacta
    18961 gagagaatat tggatgaaat ttcgaaagaa tcgaatattc caatatcata caagacaacg
    19021 ggaaaagtcc gtgaatttga agaatacatt gaaaatgatg aagtaaatca gctttatttc
    19081 ctagatatcg atattcatgg aattgagaaa aagggatttg aagtggctca gctcattcgt
    19141 cattacaatc cttacgctat tatcgtcttt atcactagtc gatcagagtt tgcgactcta
    19201 acctataaat accaggtatc agccctagat tttgttgata aggatatcaa tgatgagatg
    19261 tttaagaaga gaattgagca aaatatcttc tacacgaaga gtatgttact tgaaaatgaa
    19321 gatgttgtag attatttcga ctacaattac aagggaaatg atttaaaaat tccttaccat
    19381 gatattttgt atattgaaac aacaggggtc tctcataaat tgcgcattat tggtaagaat
    19441 tttgcaaaag agttttatgg taccatgaca gatattcagg aaaaggacaa acatactcag
    19501 cgattttatt ctcctcacaa gtcatttttg gtaaatatag gcaatatcag agaaattgat
    19561 cgaaaaaact tagaaattgt tttctatgaa gaccatcgtt gtcctatttc aagattaaaa
    19621 attagaaaat taaaagatat tttagagaaa aaatctcaaa agtgattgac aattagcaag
    19681 aaattgatat aatggttata tctgctacag atagaaggtc cgttggtcaa ggggttaaga
    19741 caccgccttt tcacggcggt aacacgggtt cgaatcccgt acggactatt ttatccgcca
    19801 tagctcagtt ggtagtagcg catgactgtt aatcatgatg tcgtaggttc gagtcctact
    19861 ggcggagtat agataaaagg gaacacagct gtgttcctct ttttgtatca atttgtatca
    19921 ccaagcattt tcataaggaa gtctgttatt tcttgagaac tttctttttt tccatgtgca
    19981 atccaagttt ggcagacacc aaaaagtgca tgagttagat agatgctact atattctaat
    20041 tcggtggtat ttagattcag ttgcataaat cgcttttgta aatctgtact aagcatgata
    20101 tgaagtttat ttcgtaagaa attttggatt tctttagtcc cattttcaga aagaagggca
    20161 gccagaagtg gttctgactc tagatattca aaaacttcta aaatagcgtc tcttttgtga
    20221 tgagcatgtt tttgaaaaat atattcaaat gtatggaata gcttgctttg atagtgctca
    20281 atcatatcat acttatcctt atagtgagta tagaagctgg aacgactaat tccggctttt
    20341 tctactaatt tgacagtaga aattttatca aatggctgtt ccatcagtaa ttgtaccata
    20401 gcattttcaa tagttcgctt tgtttttaag cgtttgttac tttcttgcat atttcctcct
    20461 tgtaaacaaa ttagactata tgtttaaaaa tagatttttt atcttgtaat ttagattttt
    20521 taatgtataa tctattatat caaaatttta gacaatatgt ttaaaaaagg agaaactaag
    20581 tttaaagaat ggaaagcaat ttaaaaaaaa ccaaccttta ttattgtcat gatcgggatt
    20641 tctcttattc cagatctgta caatatcata tttttgtcat caatgtggga tccatatggg
    20701 caattgtctg acttacctgt ggcagttgta aataatgata aagaggcttc ctataatggt
    20761 aatactatgg caataggaaa agacatggtg tccaatttaa aagaaaataa aaccttggat
    20821 tttcattttg tagatgaaga ggaaggaaag aagggattgg aagatggcga ttactatatg
    20881 gtagtgactt taccaagtga tttatctgaa aaaacaacta cattatccaa tattcaatcg
    20941 acagcagctt atcaatcatt gacaagtgag caacaaactg agataagtga ttctgtatct
    21001 caaaattcaa ctgatagtat tcaatcggct cagtcaattg tagctttagt acaagattta
    21061 cagggaagtt tagaaaactt acaaaatcaa tcttctaatc tttcgacttt aaaaaatcaa
    21121 tctaatcaag tatcacctat tacttctact tctttgatag gattgtcaag tggattaaca
    21181 gagatacaag gagatgttac tagcaaatta gttcctgcca gtcagtcgat tgcatcaggt
    21241 gtaaacgcat atactacagg tgttgataaa gtttctcagg gcgcaagtca actaagtgaa
    21301 aaaaatgcca ccttgacagg tagtttggat aaactagttt caggctcaaa caccttgaca
    21361 caaaaatctt ctagattgac agcaggagtt ggttaattac aatcaggatc tgggcaatta
    21421 gcagacaaat ccagtcagtt actttcaggt gcttctccat tagagaatag agctaataaa
    21481 ttggcagatg gatctgggaa actagcagaa ggtggaacaa agttaacttc tggattggaa
    21541 gatttacaga caggacttgc ttctttagga caaggactag gtaatgctag tgatcaactc
    21601 aaatcagtat caacagaatc taaaaatgca gagattttgt caaatccact caatctttca
    21661 aaaacagaca atgatcaagt tcctgtaaat ggaatcgcaa tagctcctta tatgatatca
    21721 gttgctcttt ttgttgcagc aatatcaaca aatatgatat ttgcgaaatt gccttcagga
    21781 cgtcatccag agagccgttg ggcttggttg aaatctcgag ctgaaataaa tggtattata
    21841 gctgttttgg caggaatttt ggtatatgga ggagttcagc ttattggttt aactgctaat
    21901 catgagatga gaatatttat tctcatcatc ctaacaagtt tagtattcat gtctatggtg
    21961 accactttaa caacgtggaa tagccgtata ggagcttttt tcttacttat tttgctttta
    22021 ctacagttag catcaagtgc aggtacttat ccacttgctt tgacaaatga tttctttaga
    22081 tctattaatc cctggttacc aatgagctat tcagtttcgg gattacgaca aacaatctct
    22141 atcaacaagt cattttccta gctgtcatac tagctctatt tactggttta ggtatgctag
    22201 cctatcaaca taagaaaatg gaagaagatt aaaaaaatcg accgattaat gaactgcacc
    22261 ccaaaagtta gacagaaaaa atctaacttt tgaggt
//
LOCUS       DAVBEM010000034        22104 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVBEM010000034 DAVBEM010000000
VERSION     DAVBEM010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22104
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.034"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(<1..389)
                     /locus_tag="VQ548_001375"
     CDS             complement(<1..389)
                     /locus_tag="VQ548_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET2654217.1"
                     /translation="MKTFFAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQIIAYIGAVLCLIIMLLLMWGL"
     gene            complement(386..550)
                     /locus_tag="VQ548_001376"
     CDS             complement(386..550)
                     /locus_tag="VQ548_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654218.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            complement(849..968)
                     /locus_tag="VQ548_001377"
     CDS             complement(849..968)
                     /locus_tag="VQ548_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET2654219.1"
                     /translation="MDFKSFIIGLVVGIFGPYMYNLIRKIFSKFPKKDTDSTP"
     gene            complement(971..1201)
                     /gene="blpU"
                     /locus_tag="VQ548_001378"
     CDS             complement(971..1201)
                     /gene="blpU"
                     /locus_tag="VQ548_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET2654220.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            complement(1270..1539)
                     /gene="blpJ"
                     /locus_tag="VQ548_001379"
     CDS             complement(1270..1539)
                     /gene="blpJ"
                     /locus_tag="VQ548_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HET2654221.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            complement(2006..2203)
                     /gene="blpI"
                     /locus_tag="VQ548_001380"
     CDS             complement(2006..2203)
                     /gene="blpI"
                     /locus_tag="VQ548_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HET2654222.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            2485..3072
                     /locus_tag="VQ548_001381"
     CDS             2485..3072
                     /locus_tag="VQ548_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HET2654223.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            3065..4654
                     /locus_tag="VQ548_001382"
                     /pseudo
     CDS             3065..4654
                     /locus_tag="VQ548_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864064.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
     gene            4665..6026
                     /locus_tag="VQ548_001383"
     CDS             4665..6026
                     /locus_tag="VQ548_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HET2654224.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMDESQKTAL
                     ETQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LIASQGQTQGTAEEPFLSQINQSIASLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLLLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     SIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            6083..6238
                     /gene="blpC"
                     /locus_tag="VQ548_001384"
     CDS             6083..6238
                     /gene="blpC"
                     /locus_tag="VQ548_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HET2654225.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FHQPIQL"
     gene            complement(6282..7622)
                     /locus_tag="VQ548_001385"
     CDS             complement(6282..7622)
                     /locus_tag="VQ548_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2654226.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGISLTFERIFKAFLFKILL
                     AVVFGMLGYMVGNTYLSYFMEPLYGIGLSFLLLRELPKKLLLFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDDYSFIWLCIIIFNFFISLAFLKWLDYDFTSLRKGILDKDFQK
                     SLTQINWIMGAYYLVIQNLSYFEYEQGIQSTTVRHLILVFYLLFFMGIIKKLDTYLKD
                     KLHERLNQEQDLRYREMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLKDSSEKLQDNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTVVSILCDNAIEASVEACQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(7636..8373)
                     /locus_tag="VQ548_001386"
     CDS             complement(7636..8373)
                     /locus_tag="VQ548_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2654227.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(8378..8716)
                     /locus_tag="VQ548_001387"
     CDS             complement(8378..8716)
                     /locus_tag="VQ548_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2654228.1"
                     /translation="MKHMIIQTQKTVYKVNVDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQYGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            8993..9322
                     /locus_tag="VQ548_001388"
     CDS             8993..9322
                     /locus_tag="VQ548_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET2654229.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(9490..10539)
                     /locus_tag="VQ548_001389"
     CDS             complement(9490..10539)
                     /locus_tag="VQ548_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2654230.1"
                     /translation="MKDLFLKRKQAFRKECLCYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEAIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(10536..11267)
                     /locus_tag="VQ548_001390"
     CDS             complement(10536..11267)
                     /locus_tag="VQ548_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2654231.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            11335..11745
                     /locus_tag="VQ548_001391"
     CDS             11335..11745
                     /locus_tag="VQ548_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET2654232.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMNATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            11755..12042
                     /locus_tag="VQ548_001392"
     CDS             11755..12042
                     /locus_tag="VQ548_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654233.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            12204..12443
                     /locus_tag="VQ548_001393"
     CDS             12204..12443
                     /locus_tag="VQ548_001393"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654234.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(12793..13929)
                     /gene="dnaJ"
                     /locus_tag="VQ548_001394"
     CDS             complement(12793..13929)
                     /gene="dnaJ"
                     /locus_tag="VQ548_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HET2654235.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(14134..14487)
                     /locus_tag="VQ548_001395"
     CDS             complement(14134..14487)
                     /locus_tag="VQ548_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654236.1"
                     /translation="MSVNKNNLSDIADYHEKIKFFEELFNLDYNPTEMLVTVERNGNV
                     IYKEFTEVAVGKSKYDHTSVFKDVMIYFSDHICQELHLYKTQDPHYNKFEFDLAKRSL
                     KITTRDNTTIFISNE"
     gene            complement(14500..16323)
                     /gene="dnaK"
                     /locus_tag="VQ548_001396"
     CDS             complement(14500..16323)
                     /gene="dnaK"
                     /locus_tag="VQ548_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HET2654237.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(16803..17327)
                     /gene="grpE"
                     /locus_tag="VQ548_001397"
     CDS             complement(16803..17327)
                     /gene="grpE"
                     /locus_tag="VQ548_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HET2654238.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(17354..18388)
                     /gene="hrcA"
                     /locus_tag="VQ548_001398"
     CDS             complement(17354..18388)
                     /gene="hrcA"
                     /locus_tag="VQ548_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HET2654239.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTGLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(18552..19061)
                     /locus_tag="VQ548_001399"
     CDS             complement(18552..19061)
                     /locus_tag="VQ548_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HET2654240.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTTTFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            19669..21606
                     /locus_tag="VQ548_001400"
                     /pseudo
     CDS             19669..21606
                     /locus_tag="VQ548_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            21604..22104
                     /locus_tag="VQ548_001401"
                     /pseudo
     CDS             21604..22104
                     /locus_tag="VQ548_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819352.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         6993 a         4580 c         3952 g         6579 t
ORIGIN      
        1 ttcaagcccc acatgagcag aagcatgatg attaagcaga gaacagcgcc aatataagcg
       61 attatttgtt ggtaggattc tcctgctgtg atacctctat acaaacaaat aatagacata
      121 aaacctgtca agccgatgaa cataagttga ttggttctag gactaaccaa atcatcatct
      181 tcaaactctc ttatcctcat ttccctagtg agataaacag taaccaaaat agaagccaag
      241 ttaataacta ctaaaagaaa ttggaaaact acggaaaaat ttaaaaactg acgagataga
      301 aatagataag tagaaacaag caagggcaac tgacctaaga acaatctcgc aaggaagatg
      361 ttccgttttt tagcaaaaaa agttttcatt tcttttctcc tttcttttta ttgatagcaa
      421 aatagatcat aactgcaatc acataggcta tggtataaaa tagctgatac caagcactct
      481 ccctaagcgg atatagaaag atggacatga ttagatacag aacgaaaata atcagtattt
      541 ttttcttcat aagatttcct cctaaatgtg cgatttatct tagttgagca agaacattta
      601 cactgctagt atagcactta ttttgacctt ggatcactca aatcataaat ggtcatcgaa
      661 acatcttgaa ttgttaaaaa atttaaaaag taagcattaa aaacatactt tcctctttat
      721 attgtattga taccaacttg tttgtagact tttcatcctg ctatcacata tcattttgac
      781 aggcgaaaca aaattaaaga aactcccctg taaattaagc tagcaaatac aggggagaaa
      841 tttatttttt agggggtact atctgtatcc tttttgggaa attttgaaaa tatttttcta
      901 attaaattat acatataagg accaaatata ccaactacta aaccaataat aaaactttta
      961 aaatccataa ttaccaccaa catgttgctg cataggctac acctccaagt atagctccac
     1021 ccgcagcacc agttgctgca ccttgccatg ttcctgtttt aatgcctagt tgaagacctc
     1081 ttgctgctgc tcctccaaca cctgctttgg caaaatctcc ccaattgcat ccgccacctt
     1141 caacgcaagc aagcatttca gtatccataa cagaaaattg tgacatcatt tttgtatcca
     1201 tgacaaatac tcctttttta aaaaactaaa ataaatcaga atagaatcct cataatttta
     1261 ctataagtct taccaactta gtcccaattt atcaccaacc atacctccta agcatgttaa
     1321 tccaccccca attgcaccaa tgtgtgctcc aacaaatgca ccagcaagtc cagctactcc
     1381 taaagtggcc aaacctgctc cagttccacc agttataatt cccgtagtga ctcctgtaat
     1441 cagtgcattt tgacaatcag tggagctata ccccccttca actttcgcaa gcatttcagt
     1501 atccataacc tctaactgtg acaacatttt tgtattcatg atgaatacct cctttttatt
     1561 ttcaatttgt taccaaagtc ttaaattcaa taaacaaata gattttttat agtatctttt
     1621 tgattttctt aaaaaagtat atacgtctac tatcttctta aaggtagcag tacctatttt
     1681 ttagtctaag atttcaataa tcttgagtat ctaaaatatc ttaatttcgt tattctcctt
     1741 gcaataaaaa gttttactat actatttatt aacttgcaga aagcaaaaaa tattagtaaa
     1801 taatagttta tagttaagtt ttttattcct accaatccat caactaagta aagcatcaac
     1861 gattacataa acgattgata atataattaa aattttgcta actatcttat tctcatcatt
     1921 cttagataac tttgatattt tgtaagtaag taaataagac agtaaattaa tagcgataat
     1981 aatactatat ttaagaatca taatcttaca aagaggacat aattcctgaa cctacacaaa
     2041 taagtgttgc tgctccccca gttatcggac cagtcgcagc agctaatagt actgctccaa
     2101 tacaaccacc gattgcagat cctaaattgc ctcttcctcc actaactatt tcgagttctt
     2161 cattatccat aacagaaaat tgttccatca tttttgtatt catgacaaat actccttttt
     2221 tcttttttta tttttgtctt gttgtaactt tgataagttt agtatatcat cgttttttaa
     2281 aatttttcat ccagatcttg aattgtcatc gaaacgtctt gaattagctt ttttatttca
     2341 agccacctct aaatgtttaa aaaaaataat ttctaatcac ttttttacca ttcaggaagt
     2401 tttaatgact attcaagatt tcataaaata tgaacttagt tttatgacat aatagaccta
     2461 tccactatat gaaaagaatt gccaatgact tcttataaac gtacatttgt tcctcaaata
     2521 gatgcgagag actgtggtgt cgctgcctta gcctcgattg ctaaattcta tggttcagat
     2581 ttttctctag ctcacttgag agaacttgca aagaccaata aagaagggac gactgctctt
     2641 ggcattgtaa aagccgctga tgaaatgggc tttgaaacaa gacctgttca agcagataaa
     2701 acgctctttg acatgagtga tgtcccctat ccatttatcg ttcacgttaa caaagaagga
     2761 aaactccaac attactatgt tgtctatcaa acaaagaaag actatctgat tattggtgat
     2821 cctgaccctt ctgtaaaaat cactaaaatg tcaaaagaac gctttttcta tgaatggact
     2881 ggagtagcta tttttctagc taccaaaccc agctatcaac cccataaaga taaaaagaat
     2941 ggtctactaa gcaagcttcc ttcctctgat tttcaaacaa aaatctctca ttgcttacat
     3001 tgttctctca agcttattgg tcactattat caatataggt ggttcttact atctccaagg
     3061 aatcttggat gaatacattc caaatcagat gaaatcaact ttaggaatca tctcagttgg
     3121 tctggttatc acctaggtta tcacctatat cctccaacaa gtcatgagct tctccagaga
     3181 ttatctccta accgttctga gccagagatt aagcattgat gtgattttat cctatattcg
     3241 ccatattttt gaacttccca tgtctttctt tgcgacacgt cgtacaggag aaatcatttc
     3301 acggttcaca gatgctaact ctattataga tgccttggct tctaccattc tttctctttt
     3361 tctggatgtt tctattctga ttcttgtagg gggagtcttg ctggcacaaa accctaatct
     3421 cttcctcctt tctcttcttt ccattcctat atacatgttc atcatctttt cttttatgaa
     3481 accttttgaa aaaatgaacc atgatgtcat gcaaagtaat tctatggtta gctctgccat
     3541 tatcgaagat atcaacggga ttgaaactat aaagtcgctc acgagtgaag aaaatcgcta
     3601 tcaaaatata gacagcgaat ttgtagatta tttggaaaaa tcctttaagc tcagtaaata
     3661 ttctatttta caaacgagtt taaagcaggg aacaaaatta gttctgaata tccttatcct
     3721 atggtttggc gctcaattag tcatgtcgag taaaatttct atcggtcagc tgattacctt
     3781 taacacactt ttttcttact ttacaactcc tatggaaaat attatcaacc tccaaaccaa
     3841 actcccatct gcgaaggtcg ctaataaccg tttgaacgaa gtctatctag tcgaatctga
     3901 atttcaagtt caagaaaacc ctgtccattc acattttttg atgggcgata ttgaatttga
     3961 tgacctttct tataagtatg gttttggacg agatacctta acagatatta atctcacgat
     4021 taaacaagga gataaggtta gcctagttgg agttagtggt tctggtaaaa caactttagc
     4081 caaaatgatt gtcaatttct ttgaacccta caaagggcat atttccatca atcatcagga
     4141 tattaaaaac attgataaaa aagtcttgcg ccgtcatatt aattacctac cccaacaagc
     4201 ctatatcttt aatggctcta tcttggaaaa tttaaccttg ggcggtaatc atatgattag
     4261 ccaagaagat attctaagag cttgtgaatt agctgaaatc cgtcaagaca ttgaaagaat
     4321 gcctatgggc tatcaaactc agctctctga tggagctggt ctatcaggag gacagaagca
     4381 acgaatagcc ctcgctcgtg ctcttttaac taaatctcct gttttaatac tagacgaagc
     4441 tactagcggt cttgatgtct tgactgagaa aaaagttata gataatctta tgtccctaac
     4501 tgataaaacc attctctttg tagcccatcg tctcagtata gccgaacgaa ctaaccgtgt
     4561 cattgttctt gaccagggga aaatcattga agttggtagt caccaagagt taatgcaggc
     4621 gcaaggcttc taccatcatc tgttcaataa ataaggagaa tgtcatgaat cctaatcttt
     4681 ttagaagcgt cgagttttat cagagacgtt accataacta tgcgacagtg ttaattatac
     4741 ctctttcatt actgtttact ttcatcttga ttttctccct tgttgccaca aaagaaatta
     4801 ctgttacttc ccaaggagaa atcgccccta caagtgtcat tgcatccatt cagtcaacca
     4861 gtgataatcc tatccttgct aatcatttag tggcaaatca agtagttgaa aaaggtgact
     4921 tactcatcaa atactctgaa acaatggatg agagtcagaa aactgcctta gaaactcaat
     4981 tacaaagact tgagaagcaa aaagaaggac ttggaatttt gaaacaaagt ttagaaaaag
     5041 cgactgatct tttttctggc gaggatgagt ttggctacca taataccttt atgaatttta
     5101 ctaaacaatc ccatgatatt gaactgggta tcacaaagac taacaccgaa gtttcaaatc
     5161 aagctaatct tgccaatagc agttcatcag ccatcgaaca agaaattaca aaagttcaac
     5221 aacaaattgg agaatatcaa gagttgagag atgctatcat aaataacaga gcacgcttac
     5281 caactggcaa tccgcaccag tcaattttaa atcgttatct tatagcctct caaggacaaa
     5341 cacaaggaac ggcagaggag ccatttttat ctcaaattaa tcaaagtatt gcaagtcttg
     5401 aatcatctat cgcaagcctc aaaattcagc aagctggtat cggaagtgta gcaacttatg
     5461 ataatagttt agcaaccaaa attgaagtac tccgcactca gtttttacaa acagcctcac
     5521 agcaacaact aaccgtggag aatcaattaa cagaattaaa agtacaacta gatcaagcga
     5581 cacagcgctt agaaaataat accttaaccg ctccaagtaa aggtatcgtt catctgaaca
     5641 gcgaatttga aggtaaaaat agaattccaa ctggtacaga aattgctcaa atattccctg
     5701 tcatcacaga tacaagagaa gtactaatca cttactacgt atcatctgac tatctcctct
     5761 tactagataa aggacaaact gtaagattaa aactggagaa gattggaaat cacggcacca
     5821 ccatcatcgg ccaacttcag agtattgatc aaactcctac cagaacagag caaggcaatc
     5881 tctttaaatt aaccgctctt gcaaaactat ctaacgagga tagtaaactc atccaatatg
     5941 gcttacaagg tcgcgtcact agtgtaacta caaagaaaac atattttgat tatttcaaag
     6001 ataaaatttt aacacattct gattaatttt cagataacac tctataacta tttattatct
     6061 tatcaaaaag gagaatcata acatggataa gaaacaaaac ctaacttcat ttcaagaact
     6121 aacaactacc gaactcaacc aaattatagg tggaggatgg tgggaagatt tcttatatag
     6181 atttaatata attgaacaaa aaaatacaaa aggatttcat cagccaatac aactataaaa
     6241 aaacaagacc aagagaacgc actctcggtc ttattttttc ttcattctat atgtattaca
     6301 gtaagtacct gacgaaaaac gtgatcttgg caggtggtat tgagactggt attgggatga
     6361 ctttccacaa ttttcataac ggtatagaga ccaactcctc tctcctcccc tttagaactt
     6421 gctccaaagg agaagatttc agaaatatcg attccctctt ctttgatgga attttcaatg
     6481 ataaaggtct cctgtgctcc attttttaaa aaggcaattg aaacatgagg ttgacaggct
     6541 tctacactag cttcaatagc gttgtcacaa aggatagaca caacggttag aaaatcaagt
     6601 agactcatcc cctctacctg aatctcctct ggaacttcga cattaaagac aatgttctta
     6661 tctctagctt ttagaaattt ccctgctagg agacttttga gggctttatc acgaatattc
     6721 accaatcgac caaggtcata tttattgtcc tgcaattttt cactagaatc ctttaagacc
     6781 gagtcgtaga tctcttttat ctgctccata tcctcctctt caatgcccag acgtaagcta
     6841 gtcaagaggt tggtgtagtc atggcgaaaa ctccgtactt ccttataaag ctcctctata
     6901 tgccgactat accgctccat ctctctgtag cgcaagtcct gctcttggtt cagtctctca
     6961 tggagtttgt ccttcaaata ggtatccaat ttcttgataa tccccataaa aaagagcagg
     7021 taaaagacta ggatgagatg gcgaacagtc gttgattgaa tcccctgttc atattcaaag
     7081 taagacagat tttgtatcac caaatagtaa gcccccatta tccagttaat ctgagtcagg
     7141 gacttttgaa aatctttatc gagaatcccc tttctcaagc tagtgaaatc atagtccaac
     7201 catttcaaaa aagctagaga aatgaagaaa ttgaaaatta ttatacataa ccaaataaat
     7261 gagtagtcat catatacttg cccttgtccc aaaaatggaa gcacaaaata ggaaacacct
     7321 ctataaaaga gattcactaa tatcattgga aagagaccat aaaagagaag gagtttttta
     7381 ggaagttctc ttaacaataa gaaagataag cctatgccgt acaagggttc cataaaataa
     7441 gatagataag tatttcctac catatagcca agcattccaa aaacaacggc caacagtatc
     7501 ttaaaaagaa aggccttaaa aatcctctca aaagtgagac taattccatc taccttaaag
     7561 aatatgacaa tttttaatcc gtgagtaaca agtgtataca acaatatcca agcaacattc
     7621 ataaactctc ctagctcagt gtaagttatt aatagcctca gacacttccc tgaccttata
     7681 acgcgcgatt agacaacttc caccattggg aaagaaaagc agtttttctt tcttatctaa
     7741 atgcaccaca ttggcaggat tgatgagaaa agagcgatgg cactgcaaga gacgaggctc
     7801 ctgcttgaga acctcctcta gactcgctgt aaattccagc ctgtctgtct tggtatagag
     7861 aataacacga tggggtcttg tggacgtttc gagatagtaa acctctttaa aaggatactg
     7921 gaattgagca aattttgatt taaagtaaaa gcaatcttcc gctagacttt tactgtcttg
     7981 accattggca tagaggaggg ctgtctcgat acgagattca aactcctctg ccgaaagggc
     8041 cttatcaata tagtccagag cagacacttg gtagcgaaag gacaggggca taaactccga
     8101 gtgagtcgtc acaaagacaa tcagggcata cggatcccga tcccgaatct ttctagccac
     8161 ttccagaccc ttcatctcct catttcgaat ctcaatatcc aaaaagaata gctgatgggc
     8221 ccccttctca tgcacctctg ccagcagttg gtctggcttg ccaaatacct caaaagagct
     8281 gggagtgata tgatgttcct tcaagagttt ctcaatcgtc gtttcaatcc tagtctgttg
     8341 ggaaaaatca tcctctaaaa caaatattct catcttctta ctctccctct ttcaaccatt
     8401 tttgacgaat ttctctatag cgacgtctgg catacttgac agcgtattga ccttcttctc
     8461 cgagaaaaag gattctttct tgaaaatcaa tcgattttaa tttatcaaga ttaaccaaac
     8521 aatttcgatg acatctcatc aaggtttccc catattggtt ctcaagatta cttaaatttt
     8581 gaagcatatt aaaactagct tcttctgtaa caatctgtac ggtatgggct ttagttggat
     8641 gtgtttggat atagtagata tcgtcgacgt ttactttata gactgttttc tgcgtctgaa
     8701 taatcatatg tttcattgga ttctcctcct aagaaaagaa taacagaaaa gttctagccc
     8761 aagcccaccc aatcctaaac agtctttgaa agctcctaaa aggattattt ttctacaaca
     8821 tcatgatgag cttacaacta ttttatcata aaattcactc agcgcaattc aagacatttc
     8881 aatgacaatt aaagatttga ataaaaaaaa agaattaaaa atgataaact aacagtatca
     8941 aaacacagtt gccagaagta agactggcac ccagattaaa ggaggcattc ccatgacaga
     9001 tacagacccc atcaaaagag ctcatacttt gattactgac ttaaacaaag cctaccaagc
     9061 atgcaaacag gcaagcgctg acgacgtccg ctttcaggag caattaaact ctattcttgg
     9121 ttttttagcc aaggctgaaa cagtggataa tcgattcttg attgaactag aaaaatttta
     9181 ccagacttcc agtcttctca tgggactcag cgctcttgat ccagatgctc caactcgcgc
     9241 cgcttggcgg gcctatgacc gcttccactt tgaccaagtc aagaccaagt taatactcaa
     9301 tgaaaatcaa agagcaaact aggaagctag ccgcaagctg tacttgagta cggtaaggcg
     9361 acgctgacgt ggtttgaaga gattttcgaa gagtataagt ctctacggac caaccattat
     9421 cctgtagtaa caaaaaagaa gctgagacag actgaactca acttcttttt tagtgtcgta
     9481 tcagcaatgt tagtcctgca tctgacgttt tacctgataa ggcaaataca agactagtaa
     9541 aaccaaacca gctcctagta aggctagaag ggccagtttt tcttggaagg taatcaaccc
     9601 aacaactaat tccacaagta aaacaaaact ggtcaatcct cgaactacct cctgtaagcc
     9661 tttttccttt tgccccttgt ccagcggaaa gagttgggtc aaatactggt agtcaaaggc
     9721 atgatagagg gccagcaact ggaagagcaa gaggtagtta aagagaacta ccactgctgt
     9781 cgcaatccaa gcttgctcga taaaaacctg cgccagtacg gaaagtaata gaagacgaag
     9841 actgagagca aagaggtcgc catttcgcag ataagaacgc agatagagat tttgccaaat
     9901 cttcccaggc accttctgaa cagcctttaa gataaagtcc agataggcac gacgcttaac
     9961 gctgtttgaa attcccttga cctgcgtaaa gagggcaaag aaacgaagca agacttgctt
    10021 acgcttgctt tcttgagaaa taacatagtc ccagtccagt ccagtttcag taaaaaattt
    10081 gctggccttt tgacgaaagt ggaaatattt tcctaccccc aataaaagca catatagcag
    10141 aaaaactggc aagccataac ccattgctaa aaataaaggc gcaaataaca gcaagaaaag
    10201 ggtctgtaca aagagccaaa agactaggga aatgccagtt tgacgcttga gatggagctt
    10261 gattgcctct tctccaacta agagaaagag cttgtctgga gcctccatat aggtggcaat
    10321 tcctccccaa agtaagagta aaacagacgt aattcctaca aacaaaagga taggccaatg
    10381 attttcagga aaatgttgta agagttgact gtactggtag gctagaaagc ccaacaggac
    10441 aagcaggaac aagacaaagt ggtcattgag cacatagcgc agataacaaa gacactcctt
    10501 acgaaaggcc tgctttctct ttaaaaacaa gtctttcata gatcctcctc tttggtcaga
    10561 gccaagtaaa tatcattcaa actagcctca ggcatatcaa aggcttcacg tagttgcagg
    10621 agattgcctt tggcacgcac ctctcccttg tgaagaatga caaaggcatc acacatcttt
    10681 tccgccgaat ccagcacgtg ggtactcatg agaatagact tgcccttttg cttctccact
    10741 tccaaaagct gaatcaaatc agaaatagcc agcggatcaa gaccaaggaa aggctcatcc
    10801 acgatgaaaa gacttggatc caccacaaaa gcacagataa tcatgacctt ctgcttcatc
    10861 ccttttgaaa aatgaacagg gaaccagtct aatttctgtt ccaaacggaa catttttaac
    10921 aagggctcta ctcgttcgaa agccactttt tgctcaatac cgtaagccat agcaaccgtt
    10981 tcgatatgct ctctgagggt caattcctca tacagactag gcgtctcagg aatgtagcca
    11041 atctgcttgc ggtagctagt cgcatctcct tgcagagtca ggccattgat attgatggag
    11101 ccactataag gtgccaacag accgataatc tcattgatcg tcgttgattt cccagcacca
    11161 ttgagaccaa tcaaaccgac caactgccca ctttcaacag taaaggacac atctttcaaa
    11221 acaggaacat gaacatagcc acctgtcagg tttttaattt ctaacatatt ttctccaaat
    11281 ctggtataat gtagctatat tatatcaaaa ttcagtacag tagaggtaga ttttatgtca
    11341 gattgcattt tttgtaaaat catcgcaggg gaaattcctg cttcaaaagt atatgaagat
    11401 gagcaggtcc ttgcctttct tgatatctct caagtaacac taggacacac cttggtcgtg
    11461 ccaaaagaac actatcgcaa tcttttggag atgaatgcta cgagcgccag ccaactcttt
    11521 gcccaagtac caaaagtagc tcaaaaagtc atgaaagtca ctaaggctgc tggtatgaat
    11581 atcatttcca actgtgaaga agtcgctggt caaacagttt ttcatactca cgttcacctt
    11641 gtgcctcgct acagtgctga cgatgacctc aagattgatt ttatcgccca cgaaccagac
    11701 tttgacaaac ttgctcaagt cgctgaaacc atcaaaaacg cttaaggagt tgctatgaaa
    11761 ttatccaacc tactgctatt tgcaggagct gcagccggaa gttatctggt tacaaaaaat
    11821 cgccaaacca tcacagatga agtcttgaat accactgacc gcgttcaagc tatcaaagac
    11881 gatgtggata ttatccaaaa tagcctgcaa atcatcgacc agcaaaaaga acttatcaag
    11941 gaataccaag aagacttgac ttacaagttt aaggtcttgg aaaaggatat ccagactaga
    12001 ctagctgtga taaaagaaat gcagggaact gaagataagt aaaaagagcc ccccggctct
    12061 tttttaaaac gtaaacaagt tatagtgaat tgaatttaga atagcacatc atagtttcta
    12121 aagcattgtt agagattact ttaaaatcct cttatcaatt tgttcatatt ctatttcaat
    12181 ctactatata tatcccatca actatgcatc ataatttagg taactcatac tcaataaaaa
    12241 tcaaaaagca aactagaaag ctaggcacag actgctcaaa acaccgtttt aaggttgtgg
    12301 atagaactga cgaagtcagc tcaaaacact gttttgaggt tgtggataga actgacgaag
    12361 tcagtaacca tacccatgac aagccgacgc tgacgtggtt tgaagaaatt tttgaagagt
    12421 atcattcacc atttcacaac taaatcgaag actttctgcc gtaatgaaaa cacctgaaac
    12481 agcttggttt cagctgtccg gaaactttaa gacttaggtt caaagtttag gtatggaact
    12541 tcgaaggagg tcgctaccgt ccgtcattac ttaggaaagt cttaaaaaat ctataaagta
    12601 aaaagagccc gacagctctt tttgtttata ctcaatgaaa atcaaaaagc aaactaggaa
    12661 actagccacg ggctgctcaa aacactgttt tgaggttgta gatacgactc acatatatac
    12721 ggcaagccga cgctgacgtg gtttgaagag attttcgacg ctgacgtggt ttgaagagat
    12781 tttcaaagag tattattctc catcaaaggc atctttaata tggtcaaaga agcctttttt
    12841 ctttggattt actttcaagt caccagcagc cgcgaattct ttcaaggcta ctttttggcg
    12901 gtcgttcaag cctgtcggtg ttacgacatt aacagtaacg tattggtcac caactgcacc
    12961 gccacgaagg ctcggtgccc ccttactacg taggcggaat ttcttaccag tctgagttcc
    13021 ctctggaata accaattcaa catcaccgtg aacagttgga atatctactg tatcaccaag
    13081 agccgcttgg acaaagttga ggttgagatt gtagaagata gtcgttcctt cacgttcaaa
    13141 cttgtcgcta gcttctacag aaactactac atacaagtcc ccataaggtc caccgttaaa
    13201 gcctgcttcg ccttgaccag cgaggcgaat ttgttgacct gtttccacac cagcagggat
    13261 tttcacatgt acgctatgag cttgtttctc atgacctgtt ccatgacagg ttgtacatgg
    13321 atatttgatt tcttttcctc gaccgtgaca gacatcacag gttacttggc gacgcatcat
    13381 accaagagga gtctgcgtat cgacgttaat gacaccagcg ccatgacagc gtccacaagt
    13441 gactggactt gtccctggct tagcaccaga gccattacat gtacgacagc cagcttcacg
    13501 atgatactta acttccttct cagttccgaa gatagcttct tcaaaggtca aattgacacg
    13561 atactggaga tcatctcctt ggcgaggagc gtttggattg cgcgaagaac cgcctccgcc
    13621 gaagaaactt gaaaaaatat cctcaaaacc accgaagcca cctgccccat tgaaaccacc
    13681 gaaaccacca gctccaccaa aaccaccatt ggcgcctgca gcaccatact ggtcataggc
    13741 agcacgtttt tggtcgtcac tcaaagtctc ataggcttct tgaacttcct tgtacttgtc
    13801 ctcagcacca ggctccttgt tgatatctgg gtgatatttt ttggaaagct tacgataagc
    13861 ctttttgatc tcgtctgccg aagcgttttt tgacaccccc agacgatcat aaaattcagt
    13921 attgttcata caagatacca agaccgtaaa attcgactga aaaataggaa atctgacgct
    13981 ggagcgacgc tcctagacag atttctcttt tttccgagaa tttaggtcgg gttcaattcc
    14041 tttcttttat attgatgaga taatactcca gccactcggc cctatccctt tttaccgaaa
    14101 aacagaggct gagttgcaac ctctgtggtt agattattca tttgaaataa aaatggttgt
    14161 attatctcta gtagtaatct tcaaagacct tttagctaaa tcaaactcaa atttattata
    14221 gtgtgggtct tgtgttttat ataggtgtaa ctcctgacat atatgatccg aaaagtaaat
    14281 cataacatct ttaaacacag aagtgtggtc atatttactc ttaccaacag ctacttctgt
    14341 aaattcttta taaatgacat ttccatttct ttccacagtc accagcattt ctgttggatt
    14401 ataatccaaa ttaaataatt cttcaaaaaa ctttatcttt tcatgataat ctgcaatgtc
    14461 agaaagatta tttttattaa cactcataac actagcccct tatttttcag taaactctcc
    14521 gtctacgacg tcatcgcctg cgtttcctgt tgcttgtgcg ccttctgctc cttcttgagc
    14581 ttgttgcgct gctgcagctt gttcgtagag tttaacagca agtccttgag ctttttcgtt
    14641 caatgcttca agttttgctt tcatgtcgtc caagttgttg tcttcttgag ctttcttaag
    14701 gtcatcaagg gcagcttggg cagcgtcacg ttctgcgtcg aagcctttac cttcagtttc
    14761 cttgattgtc ttttcagtcg caaagattgc ttggtctact tcattacgaa ggtctacttc
    14821 ttctttacgt ttcttatcgg cttcagcgtt tgcttctgca tctttcatca tgcggtcgat
    14881 ttcttcgtca gtcaaacctg agttcgattg gatgacaata gtttgttctt tttgagttcc
    14941 aaggtctttg gccttaacag acacgatacc gttcttgtcg atgtcaaatg ttacttcgat
    15001 ttgaggaatt ccacgaggtg cagctgggat atcagtcaat tggaagcgtc caagagtctt
    15061 gttatctgct gccattgggc gttcaccttg aagaacgtgg atatcaacgg ctggttggtt
    15121 gtctgctgct gttgagaaga cttgtgattt agatgttggg attgtagtgt tgcgatcgat
    15181 aagttttgta aatactccac ccattgtttc gataccaagt gacaatggcg ttacatcaag
    15241 aaggacaacg tccttgacat caccagtaat cacaccacct tggatagccg cacccatagc
    15301 aactacttca tcagggttta ctgatttgtt tggttcttta ccagtttcag ctttaacagc
    15361 ttcaacaacg gcagggatac gagttgaacc accaacaagg ataacttcgt cgatttctga
    15421 caagctcaaa cctgcatctg aaagggcttg acgaactgga acttttgtac gttcaacaag
    15481 gtcacgagtc aaatcgtcaa atttcgcacg agtcaaagtc atttccaagt gaagaggtcc
    15541 agcctcacct gcagtgataa atggcaagct gatttgtgtt gaagttacac cagaaaggtc
    15601 tttcttcgct ttttcagccg catctttcaa acgttgcatt gccatcttgt cagtagacaa
    15661 gtcgataccg ttttctttct tgaattctgc taccaagtgg tcaatgattt tttggtcaaa
    15721 gtcgtcacca ccaagtttgt tgtcccctgc agttgacaat acgtcgaaga caccgtcacc
    15781 caattcaagg atagagacgt cgaatgtacc accaccaagg tcaaatacca agattttttc
    15841 ttctttgtca gtcttgtcca aaccataagc aagagctgct gcagttggtt cgttaacaat
    15901 acgttctact tcaagaccag caattttacc agcgtctttt gttgcttgac gttgagcgtc
    15961 gttgaagtaa gccggaactg tgataacagc tttggttact ttctcaccaa ggtagtcttc
    16021 agcgtagcct ttcaagtatt gaaggatcat agctgagatt tcttgtggag tgtattcttt
    16081 tccatttgca gaaacttttt cagaagttcc catcttagat ttgatagaga taactgtatc
    16141 tgggtttgta actgcttgac gttttgcagc atcaccaacg atgatttctc cgtttttgaa
    16201 tgagactaca gatggagttg tgcggtttcc ttctgggttt gcgatgattt tgctttcagt
    16261 tccttcaaga actgcaactg ctgagtttgt tgtacctaag tcaataccga taattttaga
    16321 catgtgtttt tctccttgtt agttaatttt ctatttttct ttttgatact cttcttaagt
    16381 ggcgacgccg tcagagcttg acttcgtcaa tctctttgac taaactttga gcctaaggtc
    16441 tcaaaatttg cgcaaatagc accacggcga agagtatcgt ctttggttcg cttcgctcac
    16501 tattacaaag ccaaacatat tttatctttc ttcatagttt attgtcgttt cggacaagtt
    16561 ttctattatg taaattgcga cacgaggagt cgaaatcgat tttatttcga cgacgagtta
    16621 gtaaggaagc taggcaaacg tcatagcgat tgccgttttc tgacgagttg ctttagctac
    16681 cgtcagaatt gccgaatcga acacgcccta agctctgagt aaaaaagata gattttcttg
    16741 tgttcatcga acacttcgtc aatctcctat ttttactgcg agctttttac gagctttgta
    16801 tcttagttat acaccactac cattgctggg cgtaggatgc ggtcatggag tttgtagcct
    16861 ttttgaaaga cttgggcgat ggtatctact gggtgttcat cgtctgctgg gagagtttgg
    16921 atggccatat ggtagttatg gtcaaattcg ccatctgctg cgatttcttc aattccttct
    16981 tctttcaaag cgtgaatcaa gctttcttgc accatcccca agcccttctt cacatcatct
    17041 gtcaaacctt caactgcaag tgcacgctca aggttgtcaa gagatggtaa gattgctttt
    17101 gccaagtcct ggctacgata acgttgcaag ttttgacgtt cttcattggc acggcgttgg
    17161 atattttgca tttctgcatg agcgcgaaga tatttgtttt cgaactcatc tgcacgttca
    17221 tttgccaagt ccaactcaga cttttcagga gttgtttctt cagctgtttc cacaacttcc
    17281 tcttcttgaa cttcttctac ttcttcattt tttatatctt gggccatgtt cgcctccttt
    17341 aatgatttca atcttaatgt acttcgtaat gattactgct gaggtagcgg taaaaatctg
    17401 tcaacttcat ggtcaaaaca cggttgacca cattgacttg attgattagc tgttggtaat
    17461 ccagattaac tggaccgata atggctagaa ttccaactcc ccgataagga atgaggaact
    17521 tactactaat caccgctagg tcagctaaac aggactcttg accgtctgca acacgaacat
    17581 tttgcatctg atcctcacgc aacccctcac gaatctccaa ggccaccttt tgcggttggt
    17641 caaagaactg ataggcttct agattggcaa aattcaagag attgaccttg cccgccatca
    17701 caatgttttc gttgaacatt tccttaaaga tgtgttcaaa gagatcgatg acattatccg
    17761 ttgttgtaaa gtaacgctgg ataatctgcg gaatctccgt ccgaatcttg tagtgaatat
    17821 ctaaaacggt gtgaccgagg aaacgttcct gaatgatgct cttcagtttc agcaaatcct
    17881 cctgcaagaa gttccttgga atcagaaact gactagtaac cgttcgcgac tcgtctaggg
    17941 taaataccgc caaggctgta tgttgcccca aaacaacgat atcaaaggct gtcaaacgtt
    18001 gcctgctcgg ctcaacatcc agtgccacta ccgtacagcc actcaggcct gttagcaagt
    18061 tagcagcctc ttgcagaata tcctccaatt tgaagaattc ctgatcaaag gctttgacaa
    18121 tctcatatac ctcattttca gccagccggt gaaaatccag tgagtgtttc acatagtact
    18181 gaaaaccagc aacacttggc atccgaccgc ttgaagtatg agccttctca agcaaccctt
    18241 gtttttctag ttccgccatg tcattacgaa tggttgcact gctagagtta atagactctt
    18301 gcaaggcttt tgatccgaca ggttcgtgcg ttttggtaaa gatgtcaata atcagattta
    18361 aaatatcctg ctgacgctct gtaaccatct catcactcct ctctgtctga tcaattagca
    18421 ctcaatgcat ccaagtgcta acttatgatt ctattataca cccttaaaag agaatgtcaa
    18481 gacaaaaact caaaaaatta gcactctttt atcaagagtg ctaaaaatca atctgaagac
    18541 ctagaacctt gctattcatc tactcggtat ttccttttta gtctgaaata accatgaatt
    18601 agataagaaa tcagaaaagc atataaaaca aaaataagaa agaaagacat agaaagatcc
    18661 tctctaaaca aactcgtaca aacaacaaga ccacctaaga aagtagttgt acaggaacga
    18721 agtctagatc gcataacttc ccatttgagc cccttactca tatagacttg atcctctgga
    18781 agtaaatcag aagacgattt acgaagaatc gaacaagaac ctgctcctat caattcccaa
    18841 cctctatctc taaaatcttg cagttcatgc ttatattttt taagaaatct agaatcatag
    18901 atacggtaga tgacatcgtc tggttgacat tggtcaaaat agaacaaacc aaaacgactc
    18961 gttctatacc tccaaccttt caaatgcatc tcatgtaaat attcttcttc cttgtccaaa
    19021 tcaacaatgg tgaaaatccg aaattctact ctgctattca ttgtcttacc ccaaaattag
    19081 aaaacatgcc tggcgttatt tattagataa ttctttccac ttttgactca atctccaaaa
    19141 aatataagaa atctgaatcg caaaaactat caataaaacc caatctatta tgaaaatcaa
    19201 aaacactttc caactgaaag aactacctcc agtgacaaac tttgagcaaa acggtagtag
    19261 agctaaaaag agaagtaaaa taggaagcat ccgcattgtt aaaatccgtt tggcataaaa
    19321 aaatctttat ttaaactaaa atattatagc aaaatttacg ccagtttttg aacggctgat
    19381 gtagatattt tatactttca aaatgtttaa atgtgattat ttatttttga aaaatagctc
    19441 accagcccga ctgaaagtgc ttatagaatg ataataagtc gcctgccgaa aacagcggaa
    19501 aatagcggtg ttatgcggag ataatctgac gcgatgcgaa agtatattgc atacttattt
    19561 tcaacaattt agcagagtat ttttataagt gtgatataat agaagtataa tttgttctga
    19621 tagtttattt tatggagaag tagattttta gaatgcggag ggttcaatat ggttgagttt
    19681 ataaagtcta agaaagaaat gagtgaggag gatattaaag caaatttcat cactcctgct
    19741 attgtatcca aaggatggaa aaatggtgag catatcgctt acgaagaata cttcactgat
    19801 ggtcgaattg aggttagagg agataaggct cgtcgtaaag aaggaaaaaa atcagactat
    19861 tcactgtatt accaatttgg aactcgaatt gcaattgttg aggcaaagga taataaacac
    19921 agcgttcgag caggattaca acaagctatt gaatatggag agattttaga tgttccattt
    19981 gtttattctt cgaatggtga tggctttatt gaacacgacc gtatcacgag agaagaacgt
    20041 gagctggagt tagacgaatt ccctactcgt gaagaattat tttctcgtat gacgaaggaa
    20101 aaaggattga cgtacgaaat tacagaagct atctcaactc catactatac agacgccttc
    20161 tcaatgaaaa cgccacgcta ttatcagcaa atagctatca accgtactat tgaaacagtt
    20221 gccagaggac aaaaacgagt aatgtttgtg atggcaacag gaacagggaa aacgttcatg
    20281 gcttttcaaa ttattcatcg ccttcgaaaa gctggtttgg ctaaacgagt tttattctta
    20341 gcagatagaa acatcttagt agaccaaacg atggctgaag actttaagcc attcgaaaag
    20401 gtaatgacga aaattacacc aaaacttttg actgctcctg aaaaattaaa ttctttcgaa
    20461 atttatctag ggctttatca gcaactaact ggtgaagatg gaactgaaac acattatcaa
    20521 aaatttgaca aagacttctt tgatttaatc gtaattgatg aagcgcaccg tggttcagct
    20581 aaggaaaaca gtaactggcg taaggtaatt gattatttca gttctgcgac acagattggg
    20641 atgaccgcta ctcctaaaga aaccaagaat gcttccaata cggaatactt tggtaagcca
    20701 atctatactt atagtttaaa acagggaatc gaggatggtt ttttggctcc atatcgtgtt
    20761 atgagggtta atttagatgt ggatgtggat ggttatcgtc cagaaactgg aaaagttgat
    20821 gctaacggac aattaataga agataggtac tacggcagga aagattttga taaaaccatt
    20881 gtcattgatg atagaacgca aagagttgcc aagtttgttt ctgattatat gaagcaaaac
    20941 aatgcacgat ttgataaaac aattgttttt tgtgttgata ttgaccatgc cgagcgaatg
    21001 cgtgctgcac ttgtaaaaga gaatctagac ttagtccaag aagactatcg ttatgtcatg
    21061 caagtaactg gtgacaacgc tgaaggaaaa gctcaactgg ataactttat ggatgtcaat
    21121 tctaattttc ccgctattgt aacaacgtct aaattattaa cgacaggagt taatgctaaa
    21181 acatgtcgtt tgattgtttt agactctaat atccaatcca tgactgaatt taaacaaatt
    21241 attggtcgtg gcacacgtct ttatcctcaa aaggggaaag aattttttac gattattgat
    21301 tttcgaaatg ttaccaattt gtttgctgac cctgattttg atggtgagcc agtgaaggtg
    21361 ctggaaacag gtgcgaaaac agtcagtggt tctacgcctg gtttcgtagg tgaggaaggt
    21421 gacccagtag aaaaatatat cgttacagac aagcaggtta ccattcttaa ttctactgtt
    21481 caagtattgg atgaaaacgg gaaactgatt accgaaagcc tgaccgacta cactcgaaag
    21541 aatatcttag gtagctacgc cactttgaac gattttatca cagtttggca tacggcagat
    21601 aagaaacatt atgggaagtt tgctgatgga agcactcaag aaattgatgt tccttatgat
    21661 attcctgata cttgggagtg ggtgaggttt tctacattgg ttgaaattgt cagaggtggc
    21721 tctccacgac caatcaaaga ttatcttact tctgaagtag atggaataaa ttggataaaa
    21781 ataggtgata ctgaaaaggg tgaaaagtat ataaataatg ttaaagaaaa aatcaaaaaa
    21841 tcagggctta acaaaactag atttgtaaaa aaaggtacat ttttgttaac taattctatg
    21901 agttttggta gaccttatat tttgaatgtt gatggtgcaa tacacgatgg atggttggct
    21961 atttcgaact atgaaaactc attaaataaa gattacctat tctatattct ttcatcaaat
    22021 gtagtttatt ctcaatttct atctctaatt agtggagctg ttgtgaaaaa cttgaatagt
    22081 gataaagttg cttctattct tatc
//
LOCUS       DAVBEM010000035        22019 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVBEM010000035 DAVBEM010000000
VERSION     DAVBEM010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22019
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.035"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            53..235
                     /locus_tag="VQ548_001402"
     CDS             53..235
                     /locus_tag="VQ548_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET2654241.1"
                     /translation="MKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTIL
                     RLESASIVSELVAGLR"
     gene            535..1374
                     /locus_tag="VQ548_001403"
     CDS             535..1374
                     /locus_tag="VQ548_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET2654242.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            1392..3230
                     /locus_tag="VQ548_001404"
     CDS             1392..3230
                     /locus_tag="VQ548_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2654243.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPDVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTPAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     NLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            3243..4658
                     /locus_tag="VQ548_001405"
     CDS             3243..4658
                     /locus_tag="VQ548_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET2654244.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSAIPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            5250..6296
                     /gene="pheS"
                     /locus_tag="VQ548_001406"
     CDS             5250..6296
                     /gene="pheS"
                     /locus_tag="VQ548_001406"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HET2654245.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            6296..6805
                     /locus_tag="VQ548_001407"
     CDS             6296..6805
                     /locus_tag="VQ548_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2654246.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            6882..9287
                     /locus_tag="VQ548_001408"
     CDS             6882..9287
                     /locus_tag="VQ548_001408"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HET2654247.1"
                     /translation="MLVSYKWLKELVGIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEILSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKKFADGIQILPENAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMRGVAHEVAAIYDKAVNFKEFTLTETNEAATDALSVGIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SHVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYVLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLEVTYTATAEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSVIEAALQPAAPFVEITKFPAVSRDVALLLKAAVTHQEVIDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEKKVNA
                     EVR"
     gene            complement(9460..10461)
                     /locus_tag="VQ548_001409"
     CDS             complement(9460..10461)
                     /locus_tag="VQ548_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET2654248.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIADDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            10617..11105
                     /locus_tag="VQ548_001410"
                     /pseudo
     CDS             10617..11105
                     /locus_tag="VQ548_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            11189..11455
                     /locus_tag="VQ548_001411"
     CDS             11189..11455
                     /locus_tag="VQ548_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2654249.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGVSQPVIARMETGESSLQLDTVLKVLTSLGKTLAVVPLEQGKS"
     gene            11716..13965
                     /gene="metE"
                     /locus_tag="VQ548_001412"
     CDS             11716..13965
                     /gene="metE"
                     /locus_tag="VQ548_001412"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HET2654250.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVASDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            14029..14895
                     /gene="metF"
                     /locus_tag="VQ548_001413"
     CDS             14029..14895
                     /gene="metF"
                     /locus_tag="VQ548_001413"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HET2654251.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            15580..17793
                     /gene="pnp"
                     /locus_tag="VQ548_001414"
     CDS             15580..17793
                     /gene="pnp"
                     /locus_tag="VQ548_001414"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HET2654252.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDDQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRLELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            17809..18426
                     /gene="cysE"
                     /locus_tag="VQ548_001415"
     CDS             17809..18426
                     /gene="cysE"
                     /locus_tag="VQ548_001415"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HET2654253.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFIW
                     KHGFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            18438..19322
                     /locus_tag="VQ548_001416"
     CDS             18438..19322
                     /locus_tag="VQ548_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2654254.1"
                     /translation="MIQVRNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHIEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            19404..20747
                     /locus_tag="VQ548_001417"
     CDS             19404..20747
                     /locus_tag="VQ548_001417"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HET2654255.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYEVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEGLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            20740..21126
                     /locus_tag="VQ548_001418"
     CDS             20740..21126
                     /locus_tag="VQ548_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HET2654256.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLISLMLEEQILTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            21130..22014
                     /locus_tag="VQ548_001419"
     CDS             21130..22014
                     /locus_tag="VQ548_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HET2654257.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDMIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
BASE COUNT         6765 a         3966 c         4861 g         6427 t
ORIGIN      
        1 acaccccaaa agttagattt tttctgtcta acttttgggg tgtagttcac agttgaagag
       61 ccagaaaatt aaagtgtctt ttactcaatc aaaaatagta acgcctattc ttttggtgaa
      121 taagactatt gtttggtatg gtgcaatgcc attattaggg aaggtagatg agatgaccat
      181 attacgtttg gaatcagcta gtatagtttc tgaactagtg gcaggtttac gatagagaaa
      241 atttttaaaa atttctatgt atgattttca tttctttagt gagactgttg ccattatcac
      301 attcgaatca cacaaaataa aaaaatttct acaagtactt gacaaataga ttgaaatatc
      361 ataaaatgaa aatggttaca gagttattaa ttatttaagc ttcatgtcac cattaaaaat
      421 tgaaataaaa ggatgttatc actaatacaa gtgagcagga acctatttaa tcacatcgga
      481 agaagtttct tgatgttttt aagtaggttc cttttatttt aaaagggaaa ttttatgatc
      541 ataaaacgaa tactaaacca caatgccgta attgcgcaaa gtaaaaaaga tatcgatatt
      601 cttctttttg gaaggggcat agcttttgga agaaaaactg gagataaagt aaatccaatt
      661 gatattgaga aaagtttttt tctcaaaaat agagataata tgacccgttt tacagagatg
      721 tttattaacg ttcctttgga gttggtgtac atcaccgaaa aaataattaa cctaggtaaa
      781 ataacattgg gtaataattt tgatgaaatt atctatatta atttaacgga tcatatttct
      841 tcgagcatag aacgttataa agaagggatt attatttcga atcccctacg ctgggaaata
      901 tcgaaatatt ataaagaaga atttgaactt gggaaaaggg ctttacaaat aataaaaaaa
      961 gagttaggta ttgaacttcc aattgacgaa gctgcattca tagcgctaca ttttgttaat
     1021 gctaatttag aaaataattt tcaagagtcg tataaaatca ctgaaataat tatgggaatt
     1081 gagaaaatca ttcaagattt ctattgtact gagtttaacc aagattctat tgattattat
     1141 agattcataa ctcatataaa attatttgct catcgcttgg ttgaaaatac aacttattgt
     1201 gacgatgatg atgaagactt gttagcatta atgaaaaata aatatcctag agaatatgaa
     1261 tgtggtgaac aggtggcaat gtttatacaa actgagtaca attatttgct gacttctagt
     1321 gaattagttt atttgatggc tcatattcgt cgcttaacaa aaaatttaga ttaatagaat
     1381 aggagaatac catgagttat aaagatacgg tacaaaaaat cctcgatgta attggaggtg
     1441 aaaaaaatgt caatagagtt acccattgtg taacacgttt aagattagaa ttaaaagatg
     1501 aaaatttagt caatgatgat gatgtgaaga agataccaga tgtaataggt attatgaaaa
     1561 agaatggaca atatcaaatt atacttggta atgatgtagc taattattat aaagaattcg
     1621 ttaaacttgg caattttgaa tccgattcag ttgttcaagg gcacaaaggg aatattttag
     1681 aaagaatcat tgagtatatc gctggttcca tgactccaat cattccagca atgttagggg
     1741 gaggtatgtt gaaagtcttg gtaatcattt taccaatgct tggtatattg caatcagatt
     1801 ctcagactat tgcttttttg acattttttg gggatgctcc atattatttc ttaccgctgt
     1861 tattagctta ttctgcatca caaaaattaa aagtaacatc tacattagct atgtctgtag
     1921 caggtgtact tctccatcca aattttgttc aaatggtgca atcagggaat cctcttagtt
     1981 tatttggtgc acctgtgaca ccagctagtt atggttcatc agtcgttcca attcttatta
     2041 tggtttggtt gatgaaatat attgaaaaaa taattgctaa attaacacca gctattacta
     2101 agagtttttt gcaacctacg ctagtattat tagtatcaag ctgtattgcc ttagttgtag
     2161 tcggacctat tggagtaatt gttggtgaag gattatcaaa tctagttggg caaatgtatg
     2221 gtgtagctgg atggcttaca ttagctattc ttggtgctat tatgccattt attgttatga
     2281 ctggaatgca ttgggctttt gcacctattt ttttggcggc atctattgct actccagacg
     2341 tattaattct tccagcaatg ttagggtcaa acttagctca aggggctgct tcgatggctg
     2401 ttgcattaaa gagtaaaaat aataatacaa aacaaattgc ttttgcagca ggtttctcag
     2461 ccttacttgc agggattacc gaacctgcat tatatggtgt gactttaaaa tataaaaaac
     2521 cgctttatgc agctatgatt ggtggtggat tagcgggatt atttgcaggt cttactagtg
     2581 ttaaagcata tctatttgct gtcccatctt tgatagcgtt gcctcaattt atttattctg
     2641 atgtgccatc aaatattgta aatgctttaa ttgtggcggt catttcggtt gttattacct
     2701 ttgtattagc ttatatattt ggaatcgatg aagaagagag ttctagcaat ttagaagtta
     2761 aagctggagt ttcaaataaa aaaatgatat tttctcctat atcaggagaa atcattccgt
     2821 taagcgatgt ccaggataaa acattttcag ataaattaat tggagacgga gtagcgatta
     2881 tcccaagtga aggtaaggtt tatgcaccat ttgatgggaa aattacaaat atttttccga
     2941 ctaagcacgc aattggattg aagagtgatg agggtgttga gttactaatt catattggat
     3001 tagatactgt tgagctaaaa ggtcaaggtt ttattagtca tgtagaagaa ggagacagag
     3061 ttttcaaaaa tcagttgatt tttgaaatga acttgaattt aatcaagact aaaggctacg
     3121 aaacagttac accagtaatt gtaacgaata ccaatgattt tctagatgta ttagtattac
     3181 ctaataatca gacaatcgag cattctaagg aattactggt aatattataa tggaggaaag
     3241 ttatgaccat ttttccagat gattttcttt ggggtggagc ggttgcagct aatcaagtag
     3301 agggagcata taatgaagat ggtaagggct tatcagttca ggatgtgtta cccaaaggtg
     3361 gattaggaga agcaacagaa aatcctacag aagataactt aaaattgata ggtattgatt
     3421 tttatcataa atataaggaa gatatatcct tgttttctga aatgggcttt aatgtttttc
     3481 gtacttctat tgcatggagt agaatttttc caaaaggaga tgaggaagaa cctaacgaag
     3541 ctggtttgaa atattatgat gaattatttg atgaactaca tgctcacggg atagaaccac
     3601 ttgtaactct ttcacactat gagactccat tatatttagc aagaaaatat catggatgga
     3661 ttgataggag aatgattcat ttttatgaaa aatttgctcg aacagtttta gaaaggtata
     3721 aagataaagt taaatattgg cttacattta acgaagtaaa ctctgttttg gaattaccgt
     3781 ttactagtgg aggaatagat atacctaagg agaatctttc gaaacaagaa ttatatcaag
     3841 ctatacatca tgaattagtc gcctcgagtt tggttacaaa aattgctcgt gagattaatt
     3901 cagagtttaa ggtggggtgt atggtattag ctatgccagc ttatccaatg actccaaatc
     3961 caaaagatgt atgggcgact catgagtatg agaatctaaa ttatctattt tcagatgtgc
     4021 atgttagagg ttattatccg aattatgcaa aaagatattt taaggaaaat gacattaaca
     4081 tagagtttgc agctgaagat gcagagttat taaaaaatta tactgtagat tttttatcct
     4141 ttagctatta catgagtgtg actcaatctg ctattccaac acagtataat tcaggagaag
     4201 ggaatattat tggtggttta gtaaatcctt atttagagtc ttcagagtgg ggatggcaaa
     4261 ttgatccaat tggactacgt ataattttaa atagatatta tgaccgttat caaatcccat
     4321 tatttatagt agaaaatgga ttaggtgcta aagatcaact aataaaagat gaacttaata
     4381 acttaaccgt ccaagatgat tatagaattc agtatatgaa agaacattta ttgcaagttg
     4441 ctgaagctct acaggatggt gttgaaatta tgggctatac gtcttgggga tgtattgact
     4501 gtgtttctat gtccactgca caactttcta aaaggtacgg tctcatttat gttgatcgaa
     4561 atgatgatgg aaatggcaca ttcaatcgat ataagaaaat gtcctttact tggtataaag
     4621 gagtgattga atcaaatgga gaatccttat tcaaatagtt tgtttattga tgattagata
     4681 ttatcacggt taaggcaaca tctcattaaa tataaaataa agaggtttgg aagacatcaa
     4741 attctaaacc tctttatttt atagggggat taattaattt aattttgtta cagagagccg
     4801 attataaata gttaacttag gatagattgg ttatatatag tagactgaat ctaaaatagt
     4861 acgaaacaat tgctaaaaca tttatagaaa ttaattttac tttcccaatc gatttgtttt
     4921 catcttattt caatccgcta taaagttaga taagaataag ctaacaagca gaagtaagat
     4981 aggtcttgca agaatggtaa aaatctgata aactaagtag taattgaata ggaatctgaa
     5041 agactagtag cccaagggaa gtatatcagg gaggagagcc gtgactgcaa gctctctata
     5101 tgaaagctgg gtgaattcac ttgcgcatgg atttagaaat gaaggtctga cttgtcagat
     5161 gaaaacggat ggtaccgcgt gtcaacgctc cgagtggagt ttttggcatg tggttttctt
     5221 tttatctacg agagactgat ggaggaaata tgtcaactat tgaagaacaa ttaaaagcgc
     5281 ttcgcgaaga aacgctggct agcttgaagc agattactgc tggaaatgaa aaagagatgc
     5341 aagatttgcg tgtctctgtc cttggtaaaa agggttcgct cactgaaatc ctcaaaggga
     5401 tgaaagatgt ttctgctgag atgcgtccaa tcatcgggaa acacgtcaat gaagctcgtg
     5461 atgtcttgac tgctgctttt gaagaaacag ctaagctctt ggaagaaaag aaagtcgcgg
     5521 ctcaactggc tagcgagagt atcgatgtga cgcttccagg tcgtccagtt gcgactggtc
     5581 accgtcacgt tttgacacaa accagtgaag aaatcgaaga tatcttcatc ggtatgggtt
     5641 atcaagtcgt ggatggtttt gaagtggagc aagactacta taactttgaa cgtatgaacc
     5701 ttccaaaaga ccacccagct cgtgatatgc aggatacttt ctatatcact gaagaaatct
     5761 tgctccgtac ccacacgtct ccagttcagg cgcgtgctat ggatgcccat gatttttcta
     5821 aaggtccttt gaagatgatc tcgccagggc gtgtcttccg tcgcgatacg gacgatgcga
     5881 cccacagtca ccaattccac caaatcgaag gcttggtagt tgggaaaaat atctctatgg
     5941 ctgatcttca aggaacgctt cagttgattg tccaaaaaat gtttggtgaa gagcgtcaaa
     6001 ttcgtttgcg tccatcttac ttcccattca cagagccatc tgttgaggtg gatgtttctt
     6061 gcttcaagtg tggtggagaa ggctgtaatg tatgtaagaa aacaggttgg atcgaaatta
     6121 tgggggccgg tatggttcac ccacgtgtcc ttgaaatgag tggtatcgat gcgactgtat
     6181 actctggctt tgcctttggt cttggacaag agcgtgtagc tatgctccgt tatggaatca
     6241 acgatatccg tggattctac caaggagatg tccgcttctc agaacagttt aaataatgat
     6301 tagaaaagta gaaatggcag atgttgaggt gttggctaaa attgccaaac aagcctttcg
     6361 tgaaaccttt gcgtatgata atacggaaga gcagttacag gaatactttg aagaggctta
     6421 tagtctgaaa actttgtcaa ctgagttggg aaatcctgac tctgaaacct atttcattat
     6481 gcatgaggag gagatagctg gttttctcaa agtcaactgg ggaagtgctc aaactgagag
     6541 agaattagag gacgcttttg aaattcaacg cctctatgtg ctacaaaaat tccaaggatt
     6601 tggactaggt aagcaactgt ttgaattcgc acttgaactt gctacaaaaa atagtttttc
     6661 ttgggcttgg ctaggtgttt gggagcataa tacaaaagct caagcgtttt ataaccgata
     6721 tggttttgaa aaatttagcc aacatcattt tatggttggt caaaaagtag atacggattg
     6781 gttactgaga aagaaattaa ggtaagaaga gaattcttct attgaaatga taggaaagga
     6841 aaagaaccag tgtggcaatg gtcattctgg agaactaaat tatgcttgta tcttataaat
     6901 ggttaaaaga attggtgggc attgatgtgc catcacagga gttggctgaa aaaatgtcaa
     6961 ccacagggat cgaggtcgaa ggtgtcgaat caccagctgc cggtctttca aaaattgtcg
     7021 tcggtgagat cttgtcttgc gaagatgtgc cagaaactca ccttcatgtt tgtcaggtta
     7081 acgttggcga agaagaagag cgtcagatcg tttgtggtgc cccaaatgtg cgtgcaggca
     7141 tcaaggttat ggtggctctt ccgggagctc gtatcgctga caattacaaa atcaaaaaag
     7201 gaaaaatccg tggcttagag tcacttggaa tgatctgttc acttggtgaa ttgggtattt
     7261 ctgactcagt tgtacctaag aaattcgcag atggtattca aattttgcca gaaaatgccg
     7321 ttccaggtga ggaagtcttt tcatatctag acttggatga tgaaatcatc gaactttcta
     7381 tcacaccaaa ccgtgcagat gccctttcta tgcgtggagt ggctcacgaa gtggcagcca
     7441 tatatgacaa ggcagtcaac tttaaagaat ttactttgac agaaacaaat gaagctgcga
     7501 cagatgccct ttctgtgggc attgagacag acaaggcgcc ttactatgca gctcgtatct
     7561 tggacaatgt gactatcgca ccaagtccac aatggttgca aaaccttctc atgaacgaag
     7621 gcatccgtcc catcaataac gttgtagacg tgacaaacta catcctgctc tactttggtc
     7681 aacctatgca tgcttttgac ttggacacat ttgaagggac tgacatccgt gtgcgtgaag
     7741 cgcgtgctgg tgaaaaattg gtgaccttgg acggtgaaga acgtgacttg gacgtgaatg
     7801 acctagtcat cactgttgca gacaagccag tagcccttgc aggtgtcatg ggtggtcaag
     7861 caacagaaat ctctgaaaaa tctagtcatg ttgtccttga agctgctgtt ttcaatggca
     7921 aatctatccg taagacaagt ggtcgcctga accttcgttc tgagtcatct tctcgctttg
     7981 aaaaaggaat taatgtggca acagttaatg aagcccttga tgcggcagct agcctgattg
     8041 cggaacttgc aggtgcgacg gtgcgtaagg gtatcgtttc agcgggtgag cttgatactt
     8101 cagatgtaga agtttcttca actcttgctg atgttaaccg tgtcctcgga actgagctgt
     8161 cttatgctga tgtcgaagac gtcttccgtc gtcttggctt tggtctttct ggaaatgcag
     8221 acagctttac agtcagcgta ccacgtcgtc gttgggatat cacaatcgaa gctgatctct
     8281 ttgaagaaat cgctcgtatc tatggatatg accgcttgcc aaccagcctt ccaaaagacg
     8341 atggtacagc tggtgaattg actgtgacac aaaaactccg ccgtcaagtt cgtaccattg
     8401 ctgaaggagc aggtttgaca gaaatcatca cctatgttct aacaactcct gaaaaagcag
     8461 ttgagtttac ggctcaacca agtaacctta cggaactcat gtggccaatg actgtggatc
     8521 gttcagtcct ccgtcaaaat atgatttcag gtatccttga taccgttgcc tacaacgtgg
     8581 ctcgtaagaa taaaaacttg gccctttacg agattggaaa agtctttgaa caaacaggta
     8641 atccaaaaga agaacttcca aatgaaatca acagttttgc ctttgccttg acaggcttgg
     8701 ttgctgaaaa agatttccaa acagcagcag ttccagttga tttcttctat gctaaaggaa
     8761 tcctagaagc gctctttact cgcttgggac tagaagtgac ctatacagca acagctgaga
     8821 ttgccagcct tcacccagga cgtacagcag tcatttcact cggtgaccaa gttcttggtt
     8881 ttcttggcca agtgcatcca gtcactgcta aggcttacga tattccagaa acgtatgtgg
     8941 ctgagctcaa cctttcagtc atcgaagctg cccttcaacc tgctgctcca tttgtggaaa
     9001 tcacgaaatt cccagcagtc agccgtgacg ttgcccttct cctcaaggca gcagtaactc
     9061 accaagaagt tatagatgct atccaagctg ccggcgtgaa acgtttgaca gatatcaaac
     9121 tctttgacgt tttctcaggt gagaaattgg gacttggtat gaagtcaatg gcttatagct
     9181 tgaccttcca aaatccagaa gacagcttaa cggacgaaga agtcgcacgc tacatggaaa
     9241 aaatccaagc atcgcttgaa aaaaaagtga acgcagaagt gcgttaaacg atagtaggat
     9301 acaaattccc cctctagttt atgaacacta gaggggtgat tttatataat actcaatgaa
     9361 aatcaaaaag caaactagga agctagccgt aagctgtact tgagtactgt aaggcgaggc
     9421 tgacgtggtt tgaagagatt gtcgaagagt ataaaataat taaaatgtga tttctgtaaa
     9481 aatacatcta tgatcagagt tttgaaaact tacaatgtct aaatctttaa catagtagtg
     9541 gtttttaggc aataaaatat gatctattgt tgcattaaaa agttttggac tttggctatt
     9601 ccaagttcct ctttcaaaag gtggtagtac atttaatgcg tccctatgag agcttatttt
     9661 tgcaagtgct ccatgacgca tagttgcatt aaaatcatct gcaataatag cctttggata
     9721 ttttgaagcc aattgattat gaatgatgtt taagtcttgc ttccagattt ccattaaacc
     9781 tggcagagga ggagcagtat gcaaggcaat gatatctggt atattttgtt ttctcgaatg
     9841 taatacaatt gtcccgaacc gtgttgtatg aaaagtttta gcttctgtat agaaaccata
     9901 acttttcttg acaatcacag tcacaggagc tattccacta ttggtaggtg gagaagtgaa
     9961 aatatcatag ttggccatag aaagtccaac ttgatgaaac aatagtttga ttctctggtt
    10021 ttcttgctca cctctgatat tggtagctag ttcagggaat atagccatat cggcgtcaaa
    10081 atggctaaaa attcgctcaa tatgttgtgc ttctatttga ttagcgacgt tccaagttac
    10141 taattttaag gttttagtct tatttgatgc agaagaaagg gttttatctg ttccgaataa
    10201 tagtaatatg agcgatagta agagcaaaat gccagagtaa aaccgtattt gtttattttt
    10261 cttgtaaaaa gatagggaaa aaaatacgaa acttaaaata gcagccatag ttgcagtagc
    10321 taaggggaag gcataaatct gtgccaagat aggtctggta gatagccaaa tattaagatt
    10381 agaagatgga aaaaaagaat aagttatgat agggataaca aagagaatga ccgaaagggc
    10441 agagagaaat gttttaatca ttgtgtgagt acctcaattt gcaatggttg ctcggagcta
    10501 atgtgacttt gtgactttac ttgattgata ttctttttct tgtcttcctc atagattaag
    10561 tacaacccaa gtaaaaaaag tccaatttaa gattgaaatg attaaaaggc acagaaatgc
    10621 aagacaatta tactacaaaa ggcaaacatt tgacaatcga tagccgtcgc ttaatcgaaa
    10681 gatggaaaaa agaagggaaa tcaaatagag aaattgcctc tctgcttgga aaagttcctc
    10741 aaactatcca cactgaaatc aagcgtggga cagtccgaca atgtcttgga aaagggcgct
    10801 tcaaagaggt ttattctgcc gactatgctc aacagtctta tgaaaacaat cgcaagcgct
    10861 cggtcaagaa atcaagcttg accaaggaac taaaggaaaa gattctccac tatcataacc
    10921 aaaaattttc gcttgaaatg atggtgatgg ctaaaggggt taacgtggga atttcaacca
    10981 tttactattg gattcatcgt ggaaaattgg ggttaagcaa gcaggatctg ctttacccta
    11041 gaaaaggaaa agcgcttaag aaacaggcta gcaccaactt taaacctgct ggtcaatcta
    11101 tcgaatcata attcgctcat tcttttaaaa atacatagac gtaaaagaaa gagggttaag
    11161 tgatgaagaa tagtgctatt gggagtaatt ggaaggatgt ccatctgagc tctttagcaa
    11221 ggaggaaatc cttgaaagtg atatgcgagt ggctatcatg agcgagttga ttgaggctag
    11281 gtatgaacaa ggaatcagtc agaaaaagct ggaagaagtc agtggagtga gtcaacctgt
    11341 catagctagg atggaaacag gagagagcag tcttcagttg gatacggtct taaaagttct
    11401 aaccagtcta ggaaagacac tagcagtcgt tccacttgaa caggggaaaa gttgactaga
    11461 atcagttata gtcttttcta ataacaggtc atagtcactt ataagaatta ctaataacat
    11521 gttttagtat tctaattgga atatagctgt aaagtaagaa ttacaaagga tttgagacgt
    11581 ttgcttcaag tctttttctt ttgtccgaaa cagatatata gtttcaaact atatcaaacc
    11641 ctaatttttt acaattatac agacgctttc ttttctgtta agatagtttc aacaacaaat
    11701 tttggaggac acatcatgtc aactacaatc atcggtttcc ctcgtttggg cgaattccgt
    11761 gaattaaaat ttacaactga aaaatacttt agaaaagaaa tctcagaaga agaactttta
    11821 gcagcagcaa aagacttgcg tgctaaacac tggaacattg tcaaagaaaa aggcatcact
    11881 gaaattccat caaatgactt ttctcactat gataacttcc tagatgcggc tttccttttc
    11941 aacgtggtgc ctgcatccgt tcaaaacttg gacttgtctg accttgagcg ctacttcgct
    12001 ttgggacgtg gttaccaggg agaaaaaggg gacgttcgcg cccttccaat gaagaaatgg
    12061 ttcaacacta actaccacta catcgttcct aaatttgaaa aagacactca agtaaaattg
    12121 gctggtcaca agattttcga tgagttccaa gaagccaaag aacttggatt gaacactcgt
    12181 cctgttcttg taggtccctt cactttcctt caattgtcag actttgaaga aggcgtgaaa
    12241 gcagacgact tcgtagatag cttagtggct gcttaccaag aagtttttgc taaattggct
    12301 gaacttggtg cgactcgcat ccaattggat gaagcggctc ttgtaaaaga cttgacagct
    12361 gaagaaaaag ctctcttctt gaacctttac aacaaactct tggctgacaa aaaaggtctt
    12421 gaagtcttgc ttcaaactta tttcggtgat gttcgtgacg tatacgctga ccttgtaaac
    12481 ttaccagtag atgctatcgg tcttgacttt gttgaaggta agaaaactct tgaactcgtt
    12541 aaaggtggct tcccagctga caagactctc tatgtaggta ttgtcaatgg taaaaacatc
    12601 tggcgcaaca actacgaaaa gagcttggct gttcttgagc aaattccagc tgaaaacatc
    12661 gttttgacaa gctcttgctc acttcttcat gtgccattta caactgctaa tgaagaattt
    12721 gaaccagcac tcttgaacca ctttgccttt gcagttgaaa aattggatga aatccgtgac
    12781 ttggatgcta tccgcaatgg tcaaggttca gaagctcttg cagccaacaa agaactcttt
    12841 gcgactgagc gtgttggtga aaatgctgaa cttcgtgcgc gtatcgctgg cttgacagac
    12901 gcagactaca ctcgtttgcc agcctttgca gaacgtgaag ctatccaaga agaagctttc
    12961 aaacttccag ctcttccaac aacaacgatt ggttcattcc ctcaaacaaa agaagttcgt
    13021 gccaaacgtt tggcttaccg taaaggtgaa ttgtctcaaa aagagtacga tgctttcctt
    13081 gctgaaacga ttgacgaatg gatcaagtgg caagaagata ttgactttga tgtccttgtt
    13141 cacggtgaat ttgagcgtaa tgacatggtt gagtacttcg gtcaaaactt gtcaggatac
    13201 ctcttctcta aaaatggatg ggtacaatca tacggtatgc gtggggtaaa accaccaatc
    13261 atctggggtg atgtcactcg tcttaaccct atcactgtta aatggtctag ctatgcacaa
    13321 agtcgtacaa acaaacctgt taaaggtatg ttgactggac ctgttaccat ccttaactgg
    13381 tcattcccac gtgaagacat ctctatcaag gattctactc ttcaaatcgc ccttgctatc
    13441 aaggatgaag tgcttgacct tgaagctgct ggtgtgaaaa tcatccaaat tgatgaggct
    13501 gctcttcgtg aaaaattgcc actccgtcgt agtgactggt acgaagatta ccttgactgg
    13561 gcaattcctg ccttccgctt ggtacactca acagtagcgt cagacacaca aatccacact
    13621 cacatgtgtt actcagaatt tacagatatc atcccagcta tcgataacat ggatgcagac
    13681 gttatttcct ttgaagccag ccgttcaaac cttgaaatct tggacgaact caaagcgaaa
    13741 aacttccaaa cagaagtggg acctggggtt tacgatatcc actcacctcg tgtaccaaat
    13801 gaaggcgaaa tcgacaacac aatcgaagcc atccttgcta aagtgccaag caagaaagtt
    13861 tggatcaacc ctgactgtgg tttgaaaaca cgtggtatcc cagaaacaaa agaaagcttg
    13921 atccgccttg ttgaagcagc taaagctgcg cgtgagaaat tgtaagattg gatttctctc
    13981 catacagtgg ttgttcaaaa agaaatcaac tagaaaaggt tattacatat gtcacgccaa
    14041 acaccgtcac tctcatttga agtgttccct ccaaacccag ccgtgggtaa tggtaacatt
    14101 atttcagcct tgcaggatat gcaggagttg gctccccatt ttatcagtgt aactgccagc
    14161 aataataaat ttaatatcaa ggaaacgacg gttcgtttgg ctgactttat ccaaaatgac
    14221 ttggcgattc cgaccattgc ccacttgcca gctatttatc taactaagga caaggttgct
    14281 gaaactattg ctgacttgga caaagttggg gttcagaaaa tcttggctct tcgtggggat
    14341 attattccag acgtagaacc acaaaaggat ttccgctatg caaccgactt gattgagttt
    14401 atcaaggaac aagcccctca ctttgatatt attggagctt gctatccaga agggcatcca
    14461 gattcgccaa atcagatttc agatattcaa aatcttaaga agaaagtgga tgcaggctgt
    14521 tcgagcctcg taactcagct cttctttgac aatgagcgct tctatgattt tcaggacaag
    14581 tgtatcttgg ctgggattga tgttcctatt catgcaggaa ttatgccaat tctgaatcga
    14641 aatcaggctc tccgactctt gaagacttgt gagaatatcc atcttccacg caaatttaaa
    14701 gccatcttag acaagtatga gcatgaccct gagtcgctca gagcagcagg acttgcctat
    14761 gcagtggacc aaatcgtgga cttggtaact caggatgttg ccggtgtgca tctctatacg
    14821 atgaataatg ctgatacagc aaaatacatc catcaagcaa cccatgcctt gtttaatcac
    14881 cagtctctag gataataaaa gcaaaccatt cttctcaggt gaggggaatg gttccttttt
    14941 aatggtaaag acctcacttt ttaagaaaaa tatgataaaa tagattctgt acgtacttga
    15001 tacaaagatg aaggtattaa ataatacaat gcatttaaac tgtaagattt aacgacacga
    15061 gtgagtcaaa tcgatgttat ttgacgaaag agttagtaaa gcatttagct aatcgcccga
    15121 tagcgattag cgtgaaaggt ttagatactt taatattaaa cctttctaat gatgtatctt
    15181 gaaaactgaa cacgcctaca actctgtgga aaaagataaa tctgcctagg agcagtcgct
    15241 ccgtcgttcg atttcctatc ttcctttgag ttgcttgacg gcttggtatc ttgatgactt
    15301 gaattttggt ctcatttctt aggaaaaaag ataagcttcc tagcactcgt cgagtgcgac
    15361 gtcaccttcc tatttttcta cagaaatgtt cggcaagccg aaccgtccaa aatatcttgt
    15421 gtaattgaac acggccgaaa agctgtgtaa aaaagataaa ctgtcttgtc ttcatcgaag
    15481 acttcgtcag tttcctattt ttactttgct tttgacgtcc ttggtatctt gatctttgta
    15541 ggcaaggcgt ataatttcat caatccaaag gggattaaaa tggcaaaaca agtgtttcaa
    15601 acgacttttg cgggtcgtga gttaattgta gagactggtc aggttgctaa gcaagcaaat
    15661 ggctctgttg tcgtacgtta cggtgagtca actgtcttga ctgctgccgt tatgtctaag
    15721 aaaatggcaa ctggggattt tttcccactc caagtcaact acgaagaaaa aatgtatgcg
    15781 gctgggaagt ttcctggtgg ctttatgaaa cgtgaaggac gtccttcaac agatgcgacc
    15841 ttgacagcgc gtttgattga ccgtccgatt cgtcctatgt ttgcggaagg tttccgtaat
    15901 gaagtccaag tcatcaatac agtgctttct tatgatgaaa atgcatctgc accaatggct
    15961 gctatgtttg gttcatcttt ggcactgtct atttcagata ttccatttga cggaccaatt
    16021 gctggggtac aagtgggata tgtagatgac caaatcatca tcaacccaag tcaagaacaa
    16081 gcagagcaat ctcttcttga attgacagta gctggaacta agcacgctat caacatggta
    16141 gagtctggtg ccaaagaatt gtcagaagaa atcatgttgg aagcgcttct taaagggcac
    16201 gaagctgtca aagaattgat tgccttccaa gaagaaatcg ttgctgctgt cggtaaagaa
    16261 aaagcagaag tggaattgct tcacgtggat gctgaattgc aagctgaaat cattgcagcc
    16321 tacaacagtg acctccaaaa ggcagttcaa gtagaagaga aattggcccg tgaagctgca
    16381 actcaagcag tgaaagacca agtgactgcc gtttacgaag aaaaatatgc ggaccacgaa
    16441 gaatttgacc gtattatgcg tgatgtggct gaaatcttgg aacaaatgga acacgcagaa
    16501 gtgcgacgtt taattacaga agacaaggtg cgtcctgatg gtcgtaaggt cgatgaaatc
    16561 cgtcctttgg atgcggttgt tgacttcctt cctcgtgtac atggttcagg tctctttact
    16621 cgtgggcaaa ctcaagctct ttcagtcttg accttggctc cgatgggaga aactcaaatc
    16681 attgatggtt tggatccaga gtacaagaaa cgctttatgc accactataa cttccctcaa
    16741 tattctgtag gggaaacagg tcgttacggt gcgccaggtc gtcgtgaaat cggtcacggt
    16801 gcccttggtg agcgtgctct tgctcaagtc ttgccaagct tggaagaatt cccatacgct
    16861 atccgtctag tagcagaagt tttggaatca aacggttctt catctcaagc ttctatctgt
    16921 gcgggaactc ttgcccttat ggctggtggt gtgccaatca aggcgccagt agctggtatt
    16981 gctatgggac ttatctcaga tggaaataac tacacagtat tgacagatat ccaaggtttg
    17041 gaagatcact ttggagatat ggacttcaag gttgcaggta ctcgtgatgg gattacagcc
    17101 cttcaaatgg atatcaagat tcaagggatt actgcagaaa tcttgacgga ggctcttgct
    17161 caagccaaga aagcgcgttt tgaaatcctt gatgtcattg aagcaaccat tccagaagtt
    17221 cgtctagaat tggctccaac tgctccgaaa attgatacga tcaagattga tgtggacaag
    17281 attaagattg tcatcggtaa gggtggagaa accatcgaca agattatcgc tgaaacaggt
    17341 gttaagattg atatagacga agaaggaaat gtgtctatct actctagtga ccaagatgct
    17401 attaaccgtg ccaaagaaat tattgctggt ttggttcgtg aagccaaagt ggatgaagtt
    17461 taccgtgcta aagtcgttcg tatcgagaaa tttggtgcct ttgttaacct ctttgataag
    17521 acagatgccc ttgttcatat ctctgagatg gcttggactc gtaccaatcg tgtagaggat
    17581 ttggtagaaa tcggggatga agttgatgtt aaggttatca agattgatga aaaaggccgt
    17641 atcgatgcct ctatgaaggc tcttctacct cgtccgccaa aacctgagca tgatgaaaaa
    17701 ggtgaaaagt ctgagcgtcc tcaccgccca cgtcatcaca aggatcacaa acctaagaaa
    17761 gaatttacag aaacaccaaa agattcagaa taagaaaagg agaaatgtat ggggtggtgg
    17821 cgcgaaacca ttgatatcgt aaaagaaaat gatccagcgg cccgcaccac tttggaggtt
    17881 ttgctgactt atccaggtgt caaggccttg gcggcccacc gtctctcgca ttttatctgg
    17941 aagcacggct tcaaactctt agctcgtatg cacagtcagt tttggcgctt ttggactcag
    18001 attgagattc atccaggagc ccagattgat tcaggtgtct ttattgacca tggttctggt
    18061 ctggtgattg gagagacagc gattgttgaa aaaggcgttc ttctctatca cggagtgact
    18121 cttgggggaa cagggaaaga ctgtggcaaa cgccatccga ctgtacgaaa gggagccctc
    18181 atatcagccc atgcccaagt tatcggacct gtggaaattg gtgaaaatgc caaggtcggt
    18241 gctgcagcag ttgtcgtagc agatgtacct agtgatgtga cggttgtcgg tattccggcc
    18301 aagattgtcc gtcttcatgg taagaaagat gagcctgtca ttcacgaagt cgaagaaaaa
    18361 cgagagtatt atgtcaataa actcgagcag gctaaagatg ccagtcacag atcgtctggt
    18421 ttgtagagga tacctatatg attcaagtaa gaaacaagtt aagccaagag gagctatctg
    18481 aggcgaaaaa agtaattaac tgttgccaaa actatgacgg tacctatcgc gatccctatc
    18541 tctctaacat gcttaatttt gacccaaaca tgcccgcctt tttcctttat tatgaaaaag
    18601 gcgaacttgt tggtttatta actgtctatg cagatgacca agatgtagaa gtgacgatac
    18661 tggttcatcc aggtcatcgc cgtcagggga ttgcgcgtgc attgtttact agttttgaga
    18721 gagaaacagc ttctttcccc attcgatcag tcacttttca gacagaacgt atttttttag
    18781 agaatcatcc tgactttgcc agtaactggg gactaatcga ggatgaagag acagaaactt
    18841 ggttaggtaa ggatagaaga ccttatccgt tagcaaatgt ttcccatatt gaagttttgt
    18901 tagcagatag ttcgtatcag gatcaaatta gtcaattaaa atttcaggca ttttcagagg
    18961 aacatgaatc gagagaagtt gtggatagat atgtcgctga agctctgaag gatccagaaa
    19021 gccgactata tattttgtta aaagacggtc aggttattgg gacttgcacg gtagatttat
    19081 cgactaatac gaattacttc tacggtttag caatatcgga acctgaacgt gggaaaggct
    19141 atggaagcta cttagcaaaa tccctcgtca accaactaat tgagcaaaat gacaaggaat
    19201 ttcagattgc agtggaagat agcaatgtag gtgccaaacg tttgtatgaa aaaattggct
    19261 ttgtcaaaca gactcaggtg gtttatctga atgagaaagg agcaagggat tccgaagtgt
    19321 agagatattc ggactgaaat ttacttgaac ttttagtgat gaaactaatt gttcttggat
    19381 ttcagctttc ttgattatga tttatgatta aaatctatga caccatgtct cgtgatttgc
    19441 gagaatttgt cccgattgag gacggcaaga tcaagatgta tgtttgtggg ccaacggtgt
    19501 acaactatat tcatgtaggg aatgctcgtt caacggtagc ttttgatacc attcgtcgct
    19561 attttgagta tcgtgggtac gaggttgcct atatttccaa ttttacggat gtggatgata
    19621 agattatcaa ccgtgccagg gaagaaggca tcacgcctca ggaggttgcg gataagtaca
    19681 tcgctgcctt tcgtgaggat gtgacggcct tgggcgtgaa acctgcgact cgccatccgc
    19741 gtgtagtgga gtttatggca gacatcatcc gttttgtgga aggcttgatc gagaaaggct
    19801 ttgcctatga gagtcaaggg gatgtctatt tccgtgtaga aaaatcccac aactatgcta
    19861 aattggctaa taaaaccttg gaagatttgg agctaggtgc ttcaggtcgt accgatgaag
    19921 aaacggctcg taaggaaaat cctgtagact ttgctctatg gaaatcttcc aaaccaggtg
    19981 agatttcttg ggatagtcct tggggacctg gacgtccggg ttggcatatt gagtgttcag
    20041 tcatgtcgac agagatttta ggtgatacca ttgatattca cggtggtgga gctgacctag
    20101 agtttccaca ccacaccaat gaaattgccc aatctgaagc taaaacaggc aaggcttttg
    20161 ctaactactg gatgcacaat ggctttgtca atatcgacaa tgtcaaaatg tctaagtcct
    20221 tgggtaactt cattacggta cacgatgccc ttaaaactct tgatgggcaa gtacttcgtt
    20281 tcttctttgc gacccagcac taccgtaagc ctatcaactt cacggaaaag gcagttcgcg
    20341 atgccgagac caatctcaag tatctgaaga atacttacga acaaccattt acaggaaacg
    20401 tggatgccca agagttacaa aactttaaag ataagtttgt agcagctatg gatgaagatt
    20461 ttaatgctgc caacggtatc acagttgtct ttgaaatggc caaatggatc aactcaggga
    20521 actatgatgc aagtgtcaag caagctcttg cagatatgtt agaaattttt ggaattgtct
    20581 ttgttgagga agttttggat gcagagattg aagacttgat tcaaaaacgc caagaggcgc
    20641 gtgccaatcg tgactttgcg acagcagacc aaatccgtga ccaattggtt actcaaggaa
    20701 ttaagctcct tgataccaag gatggagtga ggtggacacg tgattgatgt caatctcatt
    20761 aacgggattg cgctagcctt tgagggagat gcggtgtatt ctatgtatat tcgccgccac
    20821 ctcatcctca aaggtatgac caagcccaat aaactccacc aagaggcgac caagtacgtg
    20881 tcagccaagg ctcaagctcg cctgatttct ctcatgttgg aggagcagat cctaacggaa
    20941 aaagaagaag aaatctacaa acgtggccgc aataccaata gtcacacaaa ggctaaaaat
    21001 gcagatgtcg tgacttatcg tatgtccacg ggatttgaag cagttatggg ctatctccat
    21061 atgactgaga atctggaacg tcttgagagt ttggtttcat ggtgcatcca aaaagtggag
    21121 ggctagaaca tgagggcaaa agaactacaa gactggtttc ctgaggctcg gatttcagac
    21181 caaccagtag agaaagaggg ctatctcacg cttcctttag cttctcagca gtggattttg
    21241 ctggaggaag ctgggctcag cgagcgtgaa aagcagttgg ttgccctttt gacccagcag
    21301 gagcaggctc gttcgctaaa cccttggtat tcctatctgg ttgaaggcaa gggacaggca
    21361 ccgcaagttt ttaaaaagat tcagttggtt tattgccatc tttcttattt tcagcaggaa
    21421 aatctggctt cttggctaga tatgatgcgg actctttttc cgaattgtca gacagtgtta
    21481 caggtcggag ctcaggatta tgttttcgtg cttcaacaag acaaatacac ttctgtaaga
    21541 gatattttaa gtgatatgat tgaagcagtt gagtatgact ttggacttcg tctttctatc
    21601 atgttgggtc aggtttggtc tcagacagga catcaagccc tatcagactt aatcaaagct
    21661 gagcgggatt tgttcaagac atggtggcgt cagggtcacc aaggtgttca tactttttct
    21721 cagctctatc tttggagtat gggagaaaga ctcgtggact tgaagccaat taaagaatgt
    21781 ctacaccaga tgattttgga tcaagatcag attcaggaaa tcattctctc tctttgggaa
    21841 aatagtgctg ttctcactaa aacagcccag caactctatc tgcaccgcaa ttctctccaa
    21901 tacaagattg ataaatggga agagttgaca gggcttcagt tgaaagagtt gaccgacctg
    21961 accttgtgtt atcaattgat tttaggttct ttgtcaacta tagttggttt gtaaagaag
//
LOCUS       DAVBEM010000036        21881 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVBEM010000036 DAVBEM010000000
VERSION     DAVBEM010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21881
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.036"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            244..1110
                     /locus_tag="VQ548_001420"
     CDS             244..1110
                     /locus_tag="VQ548_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2654258.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLHALAKKLKVSMDYFFDEQVVEKVEELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKIYMEWIKSLIDFYFYGQKEDAIVRLEGVLSQLSVSDLNYLQVSNTLFN
                     FYYDIGDLGRFNKIREKLEYQVNHLNLSTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKAYRTNYLLADLYLLMGNVSENFSSKSSVKEYFETAYFLYKLEENMSMT
                     LKVEHYIADITE"
     gene            1447..2004
                     /locus_tag="VQ548_001421"
     CDS             1447..2004
                     /locus_tag="VQ548_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase family
                     flavoprotein"
                     /protein_id="HET2654259.1"
                     /translation="MDKKNLLVLVTGSVGASNVDTYLYYIKKFYNVKVILSENSKKFI
                     SKELISYFCDKVYDEIFVEEVVPHVFLPYESDLLLILPATANVIGKIANGIADDLVTA
                     TVLNFNKKIIFCPNMNSTMWDNHIVQRNVSILKELGHIFLFESKKTYEVGLRKAIDST
                     CSMLQPQSLVKELIKLENIVLEEGH"
     gene            2225..3331
                     /locus_tag="VQ548_001422"
     CDS             2225..3331
                     /locus_tag="VQ548_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HET2654260.1"
                     /translation="MINKKIQQVVLESLQNFLNGNFISPCVVYDFGLLETVLDEFKNQ
                     IPVTFNYQLFYAVKANSNEKILEFLVDKIDGVDVASLSELDVAKKFFPPTQISVNGPA
                     FSYETLYNLIKKQYKVDINFLEHLQQFSPKESVGIRVTEPDELNNRMSRFGINICSDN
                     WTSNLQNPLITRLHFHFGEKDDKFIVKLDKILFKLQEINKLREVREINLGGGFMKLFM
                     ENRLKEFFLSLMEIYKKYDIDSTVTTIIEPGSAITSFSAYMITSPVNVSEVNEQQVIT
                     LDTSIYTNTLWFVPHIITTLNSSSKERYSTILYGNTCYEHDKYKMKVSLPRLTQNSSI
                     VFFPVGAYIKSNHSNLHRNDFMREVYLWTKNLTY"
     gene            3307..4698
                     /locus_tag="VQ548_001423"
     CDS             3307..4698
                     /locus_tag="VQ548_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654261.1"
                     /translation="MDKKLDILDKVKEYLGNKTTQILDNQYKEFLKLNDIRRAFGISE
                     KVLNNSFNFTSKEFNDLINNENYLFEYACRIREEWRKKCFNHSYRFLCSPIITDDFLN
                     TKTLRSSQIEYKYERYLSKSSIGDRAVDGFVSFNTLTANGMSAIKLCLEILNSIFFKK
                     KIDLLYSTGYYETRFLLNNLAKSGISCYEVSNCELDKDKFYNVFMMEPNRADLTLQKT
                     DFKIVEYFVKYKNNSIKVVILDISYQGSNFKLVEFLEKFKFANVIIFVVRSLIKLDQM
                     GLELTNGGIIEVFIPNHLRKLKNFIEEEFNKFRNSHGANLSLYEYCLLDNSLTLKNDW
                     NYSDLVMKFTSNFYADIKDLFMENSDIEIIHEEGVPFVFLDLIGEGKKEYEMFFQWLN
                     FFYKQLGITLYARNSFGFRNLTVEYFGIIGTERYIFKICPGVYKGLSYYLMKFLLKSF
                     SNEYLKTTDEVNR"
     gene            4695..5873
                     /locus_tag="VQ548_001424"
     CDS             4695..5873
                     /locus_tag="VQ548_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2654262.1"
                     /translation="MKNLIKLLIIRLIVNLADSVFYIVALWHVSNNYSSSMFLGIFIA
                     VNYLPDLLLIFFGPVIDRVNPQKILIISILVQLAVAVIFLLLLNQISFWVIMSLVFIS
                     VMASSISYVIEDVLIPQVVEYDKIVFANSLFSISYKVLDSIFNSFASFLQVAVGFILL
                     VKIDIGIFLLALFILLLLKFRTSNANIENFSFKYYKREVLQGTKFILNNKLLFKTSIS
                     LTLINFFYSFQTVVVPIFSIRYFDGPIFYGIFLTIAGLGGILGNMLAPIVIKYLKSNQ
                     IVGVFLFLNGSSWLVAIVIKDYTLSLILFFVCFMSKGVFNIIFNSLYQQIPPHQLLGR
                     VNTTIDSIISFGMPIGSLVAGTLIDLNIELVLIAISIPYFLFSYIFYTDNGLKEFSIY
                     "
     gene            6298..6531
                     /locus_tag="VQ548_001425"
     CDS             6298..6531
                     /locus_tag="VQ548_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2654263.1"
                     /translation="MISIDLGGTNIKITVLSNDGEIETLWSITTDTSEKGSQIISDII
                     SSIKNKLTERNIPDSDLLGIGMGSCSSYFPCKS"
     gene            6814..8763
                     /gene="mutL"
                     /locus_tag="VQ548_001426"
     CDS             6814..8763
                     /gene="mutL"
                     /locus_tag="VQ548_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HET2654264.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKIQITDNGYGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(9088..9555)
                     /locus_tag="VQ548_001427"
     CDS             complement(9088..9555)
                     /locus_tag="VQ548_001427"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HET2654265.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(9556..10761)
                     /locus_tag="VQ548_001428"
     CDS             complement(9556..10761)
                     /locus_tag="VQ548_001428"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HET2654266.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(10781..11416)
                     /gene="ribE"
                     /locus_tag="VQ548_001429"
     CDS             complement(10781..11416)
                     /gene="ribE"
                     /locus_tag="VQ548_001429"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HET2654267.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(11401..12501)
                     /gene="ribD"
                     /locus_tag="VQ548_001430"
     CDS             complement(11401..12501)
                     /gene="ribD"
                     /locus_tag="VQ548_001430"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HET2654268.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(12636..12750)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            12907..13500
                     /gene="ruvA"
                     /locus_tag="VQ548_001431"
     CDS             12907..13500
                     /gene="ruvA"
                     /locus_tag="VQ548_001431"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HET2654269.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            13510..14073
                     /locus_tag="VQ548_001432"
     CDS             13510..14073
                     /locus_tag="VQ548_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HET2654270.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRDFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            14070..14747
                     /locus_tag="VQ548_001433"
     CDS             14070..14747
                     /locus_tag="VQ548_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2654271.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     VGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(14888..15919)
                     /locus_tag="VQ548_001434"
     CDS             complement(14888..15919)
                     /locus_tag="VQ548_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HET2654272.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGRALFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNAGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(16174..16857)
                     /locus_tag="VQ548_001435"
     CDS             complement(16174..16857)
                     /locus_tag="VQ548_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HET2654273.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASVFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(16869..17813)
                     /locus_tag="VQ548_001436"
     CDS             complement(16869..17813)
                     /locus_tag="VQ548_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET2654274.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            17945..20776
                     /gene="uvrA"
                     /locus_tag="VQ548_001437"
     CDS             17945..20776
                     /gene="uvrA"
                     /locus_tag="VQ548_001437"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HET2654275.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAIKASSVEQIVDKVLELPERQRLQILSPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDNSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPNASKTLHEGALAPWNPISSNYYPNMLEQAMTAFGVAMDKP
                     FEDLSEEDKNLILYGSDGKKFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCHGYRLNDQALSVRVGGEQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            20769..21830
                     /locus_tag="VQ548_001438"
     CDS             20769..21830
                     /locus_tag="VQ548_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET2654276.1"
                     /translation="MNKRVQAFLAKMQEKELDGVIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
BASE COUNT         6639 a         3842 c         4442 g         6958 t
ORIGIN      
        1 gaaaggggct gaaagaacta ggggaacagt tgtaattaga aggtgatagg tatgaaaagt
       61 ggcgttgaag ctggataagt ttataaagag tttgaatgaa gaaatgaaaa gtaaataagt
      121 tgatgatgaa ttgcaaaaat agattttata tacaatttgt atctttcaaa tcattgattt
      181 gaattttaga tttaatcatg ttacaattaa aaatgaaatc aaatagaaga ggaagatgca
      241 aacgtgggca cactattagc aacaagatta aaaaatagac gaaaagaatt aaaaatgtct
      301 cagcgagaac tagctgaagg tatctgtaaa caggggcaaa tcagtcgatt agagagcgga
      361 gagtttactc ctggagcaga tttcttgcat gcccttgcta agaagttaaa agtcagtatg
      421 gattattttt ttgatgagca ggttgtagag aaagttgagg agttatcaga atttaagaaa
      481 ttagcacaga catttattac aaatcgcaat tatgagtctt tgaaatatat atatgaattg
      541 gagaatgtaa aagctcaccg cctatcttta gcagataaaa tctacatgga atggataaaa
      601 tctctgatag atttttattt ttacggacag aaagaagatg cgattgtacg attagagggg
      661 gtattatcac agttaagtgt atctgatttg aactatctcc aagtttcaaa caccctattc
      721 aatttttatt atgatattgg agatttaggt cgtttcaata aaattcgtga aaaactagag
      781 tatcaagtaa atcacctcaa tttgagtaca atcgaagagt tagaactatc tattaagttt
      841 aactacaacg tttgtcgtta tctatggtta cagaaaaata ttgaagaagc tattactaaa
      901 attacagcta ctataaaaca atgtaaggct tacagaacga attatctttt ggctgatttg
      961 tacttattga tgggaaatgt aagtgaaaat ttttcttcta aaagttcggt gaaagaatat
     1021 tttgagacgg catattttct atacaaactt gaggagaaca tgtcaatgac tctgaaagtt
     1081 gagcattaca ttgcagatat aacagaataa tgaatacggt gttcaagtga gcatcgtttt
     1141 tcaaacctag ttcagataca aaaaagtatc aaataaaaaa aaataaaaaa acattataaa
     1201 aacaattgac aagctaattt tgaagtgata aaataaatgc aagaaaacaa aaggagaggt
     1261 atatgagaag tttgtttaag aaaatagttg ctgtattagt tattggctta attctgttag
     1321 gaattgcgag aacacctcaa gttcataaga tggctagagg gattgatcct ggtcctgcga
     1381 attttattta gaaatcaatt tctactaatt gagtactaat tgagtattaa tgggtaaaaa
     1441 gattgtatgg ataagaaaaa tttacttgta ttggttactg gttcggtagg tgccagtaat
     1501 gtagatacat acttatatta tataaaaaaa ttctataatg ttaaagtgat actttctgaa
     1561 aattctaaaa aatttataag taaggaatta attagttatt tttgtgataa agtttatgat
     1621 gaaatatttg ttgaagaggt agttccgcac gtttttctgc catatgaatc tgacttactt
     1681 cttattttac cagctacggc aaatgtgatt ggcaaaattg ctaatggtat tgctgatgat
     1741 ttagttacag caactgtttt aaactttaat aaaaaaataa ttttttgtcc caatatgaac
     1801 tctactatgt gggacaatca catagttcaa agaaatgtat caattctaaa ggagttggga
     1861 catatatttt tatttgagtc taaaaaaaca tatgaggtag gattgcgtaa agcaatagat
     1921 tcaacatgtt caatgttaca accacagtcg ttagtaaaag aacttatcaa attagaaaat
     1981 attgtccttg aagagggaca ttaaaaacta ctgagaatat taaggagggg aaaaaatgga
     2041 aaattcatca atcgatgtag atatgctgtt ggaagaattg acacaagaag caatggtcgt
     2101 tgttgctgtt gataaggact gttaatttaa acttatggca atatatgaaa ggttactgga
     2161 tgttttaaat tatgcaggca gtagcctttt attatataca aatggataaa gtaaggataa
     2221 tacaatgatt aataaaaaaa tacaacaagt tgttttggaa tcattacaga attttttgaa
     2281 tgggaacttc atttcgcctt gtgtagtcta tgattttggc ttgctggaaa ctgtacttga
     2341 tgaatttaaa aatcaaattc ctgtaacatt caattaccaa cttttttatg ccgttaaagc
     2401 aaattcaaat gagaagatac ttgaattctt agtagataaa attgatggag ttgatgtggc
     2461 gtcattatct gaattagatg tggctaaaaa atttttccca ccaactcaaa tttctgttaa
     2521 tggtcccgca ttttcttatg aaactttata taatctgatt aaaaaacaat ataaagttga
     2581 tattaacttt ttggaacatc ttcaacaatt ttccccaaaa gaatctgttg gaataagagt
     2641 aacggagcca gatgaactta ataatcgtat gagtcgattt ggaataaata tttgcagtga
     2701 taattggact agtaatttac aaaatccttt aattacacga ctgcattttc attttggaga
     2761 aaaagatgat aaatttattg ttaagttaga taaaatatta tttaagttac aagaaattaa
     2821 taaacttaga gaggttagag aaataaatct tggaggcggt tttatgaaat tatttatgga
     2881 aaatcgtttg aaagaatttt ttctatcact tatggaaatc tataaaaagt acgatattga
     2941 tagtactgtg actacaataa tagaaccagg tagtgcaatt acttcatttt ctgcctatat
     3001 gattactagc ccagttaatg ttagtgaggt gaatgagcag caggttatca cgttagacac
     3061 atcaatatac accaatacat tatggtttgt tccgcatatt attacaacgt taaattcaag
     3121 tagtaaagag cgttatagta ctattctcta tggtaatacc tgttatgaac atgacaagta
     3181 taaaatgaaa gtttcgcttc caaggttaac tcaaaatagc agtatagtgt tttttcctgt
     3241 aggagcttat ataaaaagca atcattcaaa tttacatcgt aatgatttta tgcgggaggt
     3301 atatttgtgg acaaaaaact tgacatatta gataaagtta aggaatattt aggaaataaa
     3361 actactcaaa ttctggataa tcaatataaa gaatttttga aacttaatga tataaggcga
     3421 gcgtttggta tttcagaaaa agtattaaac aattctttta attttacgag taaagaattt
     3481 aatgatttaa ttaataacga aaattattta ttcgaatatg catgtagaat tagagaggaa
     3541 tggagaaaaa aatgctttaa tcattcttat cgttttctat gctcacctat aattacagat
     3601 gattttctta acacgaagac attgagaagt agccaaattg aatataaata tgagcgatat
     3661 ttatcgaaaa gttcgatagg cgatagagcg gttgatggct ttgtttcctt caatacttta
     3721 acagctaatg gtatgtctgc tattaaacta tgtcttgaga tattaaactc tattttcttc
     3781 aagaagaaga ttgatttatt atattcaacc ggatattatg aaacaagatt tttattaaat
     3841 aatcttgcta aatcaggtat tagttgctat gaggtaagta attgtgaatt ggataaagat
     3901 aaattttata atgtattcat gatggaaccc aatcgagccg atttaacatt acaaaaaact
     3961 gatttcaaga tagtagaata ttttgttaag tataaaaata attcaataaa agtcgttatt
     4021 ttagatattt catatcaagg ttctaatttt aaattagtag aatttttaga gaaatttaaa
     4081 tttgcgaatg taattatttt tgtggtacga tctttgataa aattagatca aatgggatta
     4141 gaattgacaa atgggggaat aatagaagtg tttattccta atcatttgag aaagttgaaa
     4201 aattttattg aagaggaatt caataaattt agaaattctc acggagctaa tctaagcctc
     4261 tatgaatact gtttgcttga taattcttta accttaaaaa atgattggaa ctattctgat
     4321 ttagttatga aatttacgag taatttttat gctgatataa aagacttgtt catggaaaat
     4381 tctgatattg aaatcatcca tgaagaggga gtaccttttg tatttttaga tttaataggt
     4441 gaaggtaaaa aagaatatga aatgtttttt caatggttaa acttctttta caaacagctt
     4501 ggaatcacat tgtatgctag aaatagtttt gggtttcgga atctaacagt agagtatttt
     4561 ggaattattg ggacagaaag atatatattt aagatttgtc caggtgttta taaagggtta
     4621 agttattatt tgatgaaatt tttattaaaa tctttttcaa atgaatattt aaaaactact
     4681 gatgaggtta atagatgaaa aatttgataa agttgctaat aattagattg attgttaact
     4741 tagcagacag tgtattttat atagtagcat tgtggcacgt tagcaataat tattcttcga
     4801 gcatgttctt aggaatattt attgcagtaa attatctacc ggatttgtta ctaatctttt
     4861 ttggaccagt tattgacaga gtaaatccgc aaaaaattct tataatatca attttggttc
     4921 aattagcagt ggctgtaata tttttattat tattaaacca aatatcattt tgggtgataa
     4981 tgagtctagt gtttatttca gtaatggcta gctccataag ttacgtgata gaagatgtgt
     5041 tgattcctca agtggtagaa tatgataaga ttgtatttgc aaattctctt tttagtattt
     5101 cgtataaagt attagattct atttttaatt cattcgcatc atttttacag gtggcagtag
     5161 gatttatttt attggttaag atagatatag gcatattttt acttgctcta tttatattgt
     5221 tgttgttaaa atttagaact agcaatgcga atatagaaaa cttctctttc aaatattaca
     5281 agagagaagt gttgcaaggt acaaagttta ttttaaataa taaattatta tttaaaacca
     5341 gtatttcttt aacgcttata aacttttttt attcatttca gacagtagtt gtaccgattt
     5401 tttctattcg atattttgat ggtccgattt tttatggtat ttttttaact attgctggtt
     5461 tgggtggtat attgggaaat atgctagcgc caatcgtaat aaaatattta aaatcgaatc
     5521 aaattgttgg tgtatttctt tttttgaacg gctcaagttg gttagtagca attgttataa
     5581 aagactatac tttatcactt attttatttt tcgtttgttt tatgtctaaa ggagtcttca
     5641 atattatttt taattcgttg taccaacaaa tacctccaca tcaacttctt ggtagggtaa
     5701 atactaccat tgattctatt atttcttttg gaatgccaat tggtagttta gttgcaggaa
     5761 cgcttattga tttgaatatt gaattagtgt taattgctat tagcatacct tattttttgt
     5821 tttcttatat tttttatacg gataatggat tgaaagaatt tagtatatat tagaaatgtt
     5881 tatgttcatt caaaagcata atgactataa ctgaaaaaga aaagtgatat ctttaaggtt
     5941 gttcttcttg gtggtgagat tcgtgagaca acccaagctt ttgtcggaaa gattaccaat
     6001 gctttgatgg ataggatgta ctttagcaag atgtttttag tggtaacggt atcgtggatg
     6061 gacgtgtaat aacctcttct ttcgaggagt attttactaa aaaactagcc ttggagcgtt
     6121 ccccagaaac ggacttactc attgactctt caaagatttg gggagaagat tttgcttcat
     6181 ctgttccttg aaaaaagtca cagcagtcat cacagacgat agtactgaac aaaactatga
     6241 agagttagaa atttatacgc aggtgattgt ataaaggatc tggaaataga taagaagttg
     6301 attagtattg acctaggtgg tacaaatatt aagattactg ttctttcaaa tgacggtgag
     6361 attgaaactt tgtggagtat tacaacagat acaagtgaga aaggttctca aattatatcg
     6421 gacatcatca gttctattaa aaataaattg accgaacgga atattcctga tagcgacctt
     6481 cttggaatcg gtatgggaag ttgctcatca tactttcctt gtaaatcata ggggctataa
     6541 actctccgtc tacttgtcct gcaacaattg aagtctgctc aaaacgccgt ccgctaatct
     6601 tttcatagac tttctccctt ttaggagcct agctttctag tttgttcttt gatttttatt
     6661 gagtatacca ctattttact ccctctggca agggactttg tctatgtgga gggattgggc
     6721 tcctatgtgg tggagctttt ctgttctttc tgaaatatgg tataatagca ctaatcaatt
     6781 tctaggaaaa tagatacgga aaggggctga aagatgtctc atattattga attgccagag
     6841 atgctggcaa accaaatcgc agctggagag gtcattgaac gtcctgccag cgtggtcaaa
     6901 gaattggtag aaaatgccat tgacgcgggc tctagtcaga ttatcattga gattgaggaa
     6961 gctggtctca agaaaatcca aatcacagat aacggttatg gaattgccca cgatgaggtg
     7021 gagttggccc tgcgtcgcca tgcgaccagt aagataaaaa atcaagcaga tctctttcgg
     7081 attcggacgc ttggttttcg tggtgaagcc ttgccttcta ttgcgtctgt tagtgtcttg
     7141 actctgttaa cggcggtgga tggtgctagt catggaacca agttagtcgc gcgtgggggt
     7201 gaagttgagg aagtcatccc agcgactagt cctgtgggaa ccaaggtttg tgtggaggat
     7261 ctctttttca acacgcctgc ccgtctcaag tatatgaaga gccagcaagc ggagttgtct
     7321 catatcattg atattgtcaa ccgtctgggc ttggcccatc ctgagatttc ttttagcttg
     7381 attagtgatg gcaaggaaat gacgcggaca gcagggactg gtcaattgcg ccaagcaatc
     7441 gcagggattt acggtttggt cagtgccaag aagatgattg aaattgagaa ctctgaccta
     7501 gatttcgaaa tttcaggttt tgtgtccttg cctgagttga ctcgggctaa ccgcaattat
     7561 atcagcctct tcatcaatgg tcgttatatc aagaacttcc tgctcaatcg tgctattttg
     7621 gatggtttcg gaagcaagct tatggttgga cgttttccac tggctgtcat tcacatccat
     7681 atcgaccctt atctagcgga tgtcaatgtg catccaacta agcaagaggt gcggatttcc
     7741 aaggaaaaag aactgatgac cctggtttca gaagctattg caaatagtct caaggaacaa
     7801 accttgattc cagatgcctt ggaaaatctt gccaaatcga ctgtgcgcaa tcgtgagaag
     7861 gtggagcaaa ctattctccc actcaaagaa aatacgctct actatgagaa aactgagccg
     7921 tcaagaccta gtcaaactga agtagctgat tatcaggtag aattgactga tgaagggcag
     7981 gatttgaccc tgtttgccaa ggaaaccttg gaccgattga ccaagccagc aaaactgcat
     8041 tttgcagaga gaaagcctgc taactacgac cagctagacc atccagagtt agatcttgct
     8101 agcatcgata aggcttatga caaactggag cgagaagaag catccagctt cccagagttg
     8161 gagtttttcg gacaaatgca cgggacttat ctctttgccc aagggcgaga tggactttac
     8221 atcatagatc agcacgctgc tcaggaacgg gtcaagtacg aggagtaccg tgaaagcatt
     8281 ggcaatgttg accagagcca gcagcaactc ctagtgccct atatctttga atttcctgcg
     8341 gatgatgccc tgcgtctcaa ggaaagaatg cctctcttag aggaagtggg cgtctttcta
     8401 gcagagtacg gagaaaatca atttattcta cgtgaacatc ctatttggat ggcagaagaa
     8461 gagattgaat caggcatcta tgagatgtgc gacatgctcc ttttgaccaa ggaagtttct
     8521 atcaagaaat accgagcaga gctggctatc atgatgtctt gcaagcgatc tatcaaggcc
     8581 aatcatcgta ttgatgatca ttcagctaga caactcctct atcagctttc tcaatgtgac
     8641 aatccctata actgtcctca cggacgtcct gttttggtgc attttaccaa gtcggatatg
     8701 gaaaagatgt tccgacgtat tcaggaaaat cacaccagtc tccgtgagtt ggggaaatat
     8761 taaaagtata aaaaagtctg ggaaaaattt tcaaaatcag aaaaacgcat aaaatcaggt
     8821 gttcaaaaac cttgatttta tgcgttttat catggaaata gttacttcat gttttcctaa
     8881 ttcttttcga aactcttttt aaaccacgtc agttttatca gtaatctcaa aacagtgttt
     8941 tgagctaatt ttgccagttt tatctgtaac atcgaagttg tgtttgacca ctctgcgact
     9001 ggtttcctag tttgctctat gattttcaca gagtattaaa ttgcgatttt gccaagtttc
     9061 tttattcgtc taaaagtaga gtctgttcta tgcgtctaat gtacgaatta ggttgaccat
     9121 ttcaatagct ccttgtgcac actcagaacc cttatttcct gctttggtac cagctcgttc
     9181 tatggcttgt tcaattgtat ctgtcgttag cacaccaaac ataacaggaa tttcgctatt
     9241 taaactgatt tgggcgattc ccttagatac ctcgctacat acataatcat aatgacttgt
     9301 attccctcta atgacagctc ccaagcagat aattgcatca tattttttac tttttgccat
     9361 ttttgatgca atcagtggta tttcaaaagc tcctggaacc caggctacct ctatatcttt
     9421 ctcgtttaca ttctctcttt tgagattatc tagtgctcca gataataatt ttgaagttat
     9481 aaattcatta aatctcgcta caacaatacc tattttaata ttgtttgcta ctaaattacc
     9541 ttcataagtg ttcatttatt tttcctccat atttaaaatg tgacccattc gatttttctt
     9601 tgtttctaaa taaaaactat cgtaaggatt ggcttctatt tcgattgata ttctactgga
     9661 aatggtaatt ccatattttt ctaactgttc aaccttgtca ggattatttg tcagtaaatg
     9721 aagtgactga agtcccagat ctttaagcat ttgtgctcca atatgatatt ctcttaaatc
     9781 accttcaaag cctaatgcaa gattggcatc aagcgtatcc atgccttgat cttgtaaatg
     9841 ataggctttt aatttattga taagtccaat tcctcgtccc tcctgtcgca agtaaagtaa
     9901 gacacccgaa ccattctcaa caatcatttt catagcttta tcgaattgct gtccacaatc
     9961 gcaacgtaaa gagcctaaaa catctcctgt taaacattcg gagtggaccc gacataatac
    10021 attggcttca tcctctatat ttcccataat aagagcaaga tgatgttccc catttagttt
    10081 atctatatag ctaattgctt tgaaattacc gtatctagta ggcatattga cagttgaaac
    10141 tcgttctacc agctgatcat atacttttct atattcttgt aattctttga tggtaattag
    10201 tggaatgttg tgtttcttcg agaactgaat taaatcatct gttctcatca ttttgccatc
    10261 atgattcatt atttcacaac ataggccaca ctcttttagt ccagctaatt ttaataaatc
    10321 aacagttgct tctgtgtgtc catttctttc tagaacacca cctttttttg caattaaagg
    10381 aaacatgtgt cctggcctgc gaaaatcaga gggtgttata tcttcagcta cacacatacg
    10441 tgcggtcagt cctctctcct cggcagaaat acctgtggtc gtttctttat aatcaattga
    10501 aactgtaaaa gcagtcttat gattatctgt attgttttca accataggtg aaagcattaa
    10561 ttgattagct aaactttcgc tcataggcat acaaattaat cctttggcat aagtagccat
    10621 aaaattaaca ttttctgttg tagctgcttg tgcagaacaa attaagtctc cttcattttc
    10681 tctatccttg tcgtctataa caagaacaag tcgtcccttc tgcaatgctt ctaatgcttc
    10741 ttgtattttt cgatattcca ttgactgatt atcctttctg ctaaaatcca ttttgatata
    10801 atagttcctt agatatttct gattttggag agttatccat cagtttttgc acatatttac
    10861 ctaagatatc attttcaaga tttactgtac tcccgacttg tttactctta agaatggttt
    10921 gttccaaggt atgagggata acagatactg aaaagtttac tttggagact ttagcgacag
    10981 tcagactaat gccgtcaatt gtaatagatc ctttttcaac tattaaatct aaaatttctt
    11041 tttgtgtgtt gatttgatac catacagcat tatcatcttt ttttattgac gagatttttc
    11101 ctgtaccatc aatgtgtcct gtaacgacgt gacccccaag tcgaccgttg acagataagg
    11161 ctctttctag attcacctca cttccatgtt ttaatagagt aagagctgtt cgactccatg
    11221 tttcattcat tacatcaact gtaaaggatt gatgattgaa atgagtaact gtaagacaga
    11281 taccatttac tgctatacta tcgcctaaat ggatatccgt taatattttt gaggctttaa
    11341 ttgatagttt acaattacga gagtctttct gtattctttc aacttttccg atttcttcaa
    11401 ttattcctgt gaacatggat aaatcacttc actttctatg agatagtcat ttcctatttg
    11461 agaaaaagca taaggtttca atctaatagc gtcatttggc aaagaaatgc cttcacctcc
    11521 gacaggaaac ttggcactgc ctccaaaaat ttttggtgca atatatattt tcagctcatc
    11581 aacaatttgt tgttccaaag cactccaatt cattagactg cccccttcta gaactaggct
    11641 atcaatctgc atgtttccta gatgttgcat taaactcgat aagtctatat gattgccttt
    11701 tttctttatg gaaagtattt cacagccatg attttgatat agcttcattt tatttttgtc
    11761 ttcagaggaa gtggcaatgt aagttttaat atcatttgct gtttttacga ttttagaggt
    11821 aagaggagtt cgtaaatgtg tatcgcatat gatacggata ggatttttcc cttcctccaa
    11881 tctacatgtc agcaaaggat cgtcttgaat aacagtattg actcccacca taattgcact
    11941 aacatggtgt cgtaactgat gcacatgctt tcttgcttct tcttcagtaa tccatttgga
    12001 ttgatttgtt ttagtggcta tttttccatc cattgacatt gcatatttca taaaaacata
    12061 gggtacatgc tgggtaatat actttctaaa actttttatt aagttaagac actcattttc
    12121 taaaattcca acagtaactt gaagattatt ttcctcaagt atctttactc cttttccaga
    12181 tacaatagga ttacagtcta ggcttccaat gactactctt gtaataccac tatcgattat
    12241 agcatctata cagggaggtg ttttcccgaa gtgacaacag ggttcaagtg ttacataaag
    12301 cgtcgctccg acaggggatt ctctacagtt tttaagagca tttctctcag catgtgggcc
    12361 accaaaaaac tcatgataac cttgtccgat gatgtgatta tcttttacaa taactgcgcc
    12421 gaccatagga ttgggattga cgtaaccagc ccctttttgt gccagtttta ttgctaattt
    12481 catatatttt gaatcgctca tctcactacc tccaaaaaaa atataccttg aataggggac
    12541 tactcaaggc atacaaaaga aaacttatgc gattaacaaa aatactctga aatgacaagt
    12601 aatcatttca gagcacgcaa aaagcacaaa tatactttta tcttctttca tccagactat
    12661 actgtcggct ttggaatttc accaaatcat gcctttcggc tcgtgggcta taccaccggt
    12721 agggaattac accctgccct gaagatagtt attcaattac agatgattat agtacttaat
    12781 tttgaatatg tcaacagata aataccgatt gtttttgata tactgtattt gtgataatcg
    12841 attctcgctc ctcggataaa gaaaatatga tatactagat aaacgaaata agagagaagg
    12901 aatactatgt acgcatattt aaaaggaatc attaccaaaa ttactgccaa atacattgtt
    12961 cttgaaacca atggtattgg ttatatcctg catgtggcca atccttatgc ctattcaggt
    13021 caggttaatc aggaggctca gatttatgtg catcaggttg tgcgtgagga cgcccatttg
    13081 ctttatggat ttcgctcaga ggatgagaaa aagctctttc ttagtctgat ttcggtctct
    13141 gggattggtc ctgtatcagc tcttgctatt atcgctgctg atgacaatgc tggcttggtt
    13201 caagccattg aaaccaagaa catcacctac ttgaccaagt tccctaaaat tggcaagaaa
    13261 acagcccagc agatggtgct ggacttggaa ggcaaggtag tagttgcagg agatggcctt
    13321 cctgccaagg tcgcagtgca agcaagtgct gaaaaccaag aattggaaga agctatggaa
    13381 gccatgttgg ctctgggcta caaggcaaca gagctcaaga aaatcaagaa attctttgaa
    13441 ggaacgacag atacagctga gaactatatc aagtcggccc ttaaaatgtt ggtcaaatag
    13501 gagcagagaa tgacaaaacg ttgttcgtgg gtcaagatga ccaacccact ctacatcgcc
    13561 tatcatgatg aggagtgggg ccagcccctc catgatgacc aagcgttgtt tgagttattg
    13621 tgtatggaaa cctatcaggc aggcctgtct tgggaaacgg tactcaacaa acgccaagct
    13681 ttccgagaag cctttcatag ctatcaaatt cactcagtcg cagagatgac tgacactgaa
    13741 ttggaagcca tgctggagaa tccagctatc attcgaaata gagccaagat ttttgctaca
    13801 cgcgctaacg cccaagcttt tctacagtta caggcagagt acggctcttt tgatgcctat
    13861 ctttggtctt ttgttgaggg gaaaactgtc gttaacgatg ttcctgatta tcgccaagcc
    13921 ccagctaaaa cacccttatc tgagaaatta gccaaagatc tcaaaaaacg agacttcaag
    13981 ttcacaggcc cagtcgccgt attgtctttt ctacaggctg cagggctagt tgatgaccac
    14041 gagaatgatt gtgagtggaa aggtcttaaa tgatgtctaa caaaaataag ggaattctga
    14101 tttttgcgat tctctataca gtcctctttg tgtttgatgg cgttaaattg ctggcttctt
    14161 taatgccatc tgccattgca aattatcttg tttatgtagt tttagctcta tatggctcct
    14221 tcttattcaa ggatagattg atccaacaat ggaaggagat tagaaagact aaaagaaaat
    14281 tcttctttgg cgtcttaaca ggatggctct ttctcattct gatgactgtt gtctttgaat
    14341 ttgtatcaga gatgttgaag cagtttgtgg ggctagtcgg acaaggtcta aatcagtcta
    14401 atattcaaag cacttttcaa gagcaaccac tactgatagc tgtttttgct tgtgtcattg
    14461 gacctctggt agaagaatta tttttccgtc aggtcttatt gcattacttg caggaacggt
    14521 tgccaggttt actaagcatt attctggtag gacttgtttt tgctctgact catatgcaca
    14581 gtttggctct atcagagtgg attggtgcag ttggttactt aggtggaggc cttgcctttt
    14641 ctattattta tgtgaaagaa aaagagaata tctactatcc actacttgtt cacatgttaa
    14701 gcaacagcct ctccttaatc attttagcta tcagtatagt aaaatgaaat aagaacagga
    14761 cagtcaaatc gatttctaac aatgttttag aagtagatgt gtactattct agtttcaatt
    14821 tgctgtaata tgtgatgaaa atgccagtaa tgataccgag aaaaaagctg agaaactttt
    14881 cccagcttta tttgttatag tcaaagcgaa tgacttgttc ctgtgcatct acatgagcat
    14941 ggaccccaaa gggtacaatt gctcttggag ttgcgtggcc ggcattcaga ttatagacaa
    15001 tcgggatatt gctgtcaatg atatccaata gtgcctcttt atagtcgtca tggaaagttt
    15061 catccatagg ttttccgacc aagagtccat tgatgaccgc gaatatgcca gtgtccttta
    15121 aagttagcaa catctttttg aagtcttctg gcttaggctt ttcttcgctt gtttcgagca
    15181 agaggatttt cccttcccag tctgacaagt cagggaaaag tttgtatttt tggcagagct
    15241 ccgtgctatc tgcgtatcga gagttgtcaa agatatcgta gagggattcg aggcaaccac
    15301 cgaggatttt cccctcgaat agtgcccttc cttgcaacaa gtcaaaacct gtatttgtat
    15361 gactgacacg aggtgttccc agggccgtgg gactaaaatc agttcgttcc tcataccaaa
    15421 cgtcactagg gcggatttct gaaattcttc ccgtctcaat caattcttta aagtagtgaa
    15481 ggctataggc tagcatttct ttgtctaatt cacaaatgtc tgctaaaaag gattgaccat
    15541 aaaaagtctt gattcctaat ttatgcaaca tgaggtggtt catggttgta tccgagaagc
    15601 caagaaaaat tttttgcttg ataacctttt ggagttggtc attttcaaaa agataaggta
    15661 gcaagcgata ggtatcgtct ccaccgatgg cacataggat catgtcgatg ctatcatcag
    15721 aaaaggcatg aatcaaatcc tctgcacgag cttcaggatg gtccttgata aagtctaatc
    15781 cttttaacga atggggcaaa aagatgggat tgagtcccag atccttgaga cgttggatac
    15841 ccaagtccac ttcgtgtttg acaaaatcct ctccgataat gccactagat aaactaacaa
    15901 taccaatagt agaaaccata tctcatcctc ctagaaatag attgagccta ttttatcaca
    15961 aaatataaga gaaagctatg tgggatttca gaagaatact tttaatactc ttcgaaaatc
    16021 tcttcaaacc acgtcagttt tatctgcaac ctcaaagctg tgctttgagc aacctgcagc
    16081 tagcttccta gtttgctctt tgattttcat tgagtataac tcaaaaaagt aagtgaaaaa
    16141 gcaaccgcac ctgcagttgc ttttatcgtt ttcttattct tgatagcgtg ttggtcctgc
    16201 acttgcacta cggatattca agcgtttctt gagatagaag cgaagggcta ggagggctgc
    16261 tccaataata gctagtggca atggatccag tactgggtta aggctagctg gtaggaagct
    16321 tgttgcaaag aagacaagca accaaaggaa cacagaagct aggataacta gtacagattt
    16381 ccagaaaggt ggacgttgac tgcgatccat atctggtcca tagtattggt aaacaaagta
    16441 gtacatcaag tagaaggcaa atccaccaac cagtccaact aatagaagag taatcaatcc
    16501 atagccgaaa gcttgatctg ccgcaaagaa ggttgtgagg gcgctgacaa gggcaaagag
    16561 gctagtgatg aaaagagctg agtccataat catcagtttt gggtcatcat tttcttttgg
    16621 atgctctttt tcgtactgct ctttgacagt gaagctatga gcccaatgag ttggtgcgcc
    16681 gtatagggaa cgggcagttg tacctttaga ttgctcctca aggatttggg gaatgacttc
    16741 ctcaaaaata gtctggattt cagcgtctgt tttcccatct ttgatgaatt gttgggtagc
    16801 aatgtggaca aactcttggt ttttcttagt taatttttgt agatcaattt gagacatagg
    16861 aactcctttt agaaccattt tttatggatg agatagagag tgagcgagac actcatagca
    16921 aaggcgataa agacgattaa ccagaaggca tttggctctc cgtttagggg aatttcatta
    16981 tccttaaagt tcatcccgta ggcagaaaag accatggttg ggatggacat gacgatggtc
    17041 acaagggcca aggttttcat gatgttgttc tggttgttag aaatgataga ggcaaaggtc
    17101 tctgtcatag aatgcaagac gtttccataa atatctgcca tctcgatggc ctgttgggtt
    17161 tcaatcaggg tgtcttcaag caggtcttcg tcctcaaggt atttcttgat attgctggtt
    17221 gaactggtca atttcttaat cacgcgctca tttgttttga gggaggcctt gaaatagacg
    17281 atagtttttt ccaattccat gagctcaatc aattcttcat tacgagttga ttgatgcagt
    17341 tgactttcga tttgttcact cttgcggtcg attgaacgaa gggctgttag gtaaagctct
    17401 gcattgcgat aaagaatttg aaagataaaa cgtgaacgca tgaaggtata gaaattacgc
    17461 aatcgacggt tgataaagac atcaaggaca ggtagtggtt ccaaacacgt agtgataatg
    17521 gtttcctcag tgatgataat accaagcggg atggttacgt agtaggtgcg gttatttctt
    17581 tcctccgtga ccggcacgtc tacgataatc agggtatact cgtcttcaat ggtaatacga
    17641 gacatttctt ccgcatcgag cggtgctcga aggtcggcaa tatcaatatc gaaggtgttg
    17701 gcgatttcga gtgattcatt ttgagtcgga ttgacgagat tgatccaagt acccggttca
    17761 agcgtatcga tctctttaaa ttcagttgtt gtagagagaa aaacttgttt catatccctt
    17821 atcctttctc atttttcaga ttttttcaca ctgtactatt atactacaaa atcggccttt
    17881 tgggtaatag aatctcactt tttttggtat aatggtaagc aataatggac tagaaagaac
    17941 aaagatgcaa gataaaattg tcattcatgg ggcgcgtgcc cataatttaa aaaatattga
    18001 tgtggagatt ccgcgagaca agttggttgt cgtgactggc ttgtcaggtt cagggaagtc
    18061 cagtttggct tttgataccc tctatgcgga gggacaacgt cgctatgtag agagtttgtc
    18121 cgcctacgct cgtcagttct tgggaaatat ggaaaaacca gatgtagatg ccattgatgg
    18181 tctcagccca gctatttcta tcgaccagaa aacgactagc aaaaaccctc gctcgacggt
    18241 gggaacaacg actgaaatca atgactatct gcgtctcctc tacgcgcgtg tggggacgcc
    18301 ttactgtatc aacgggcatg gggctatcaa ggcttcttct gtggagcaaa tcgttgataa
    18361 ggttttggag ttacctgaac gccagcgctt gcagatcttg tctcctgtca tccgcaagaa
    18421 aaaaggccaa cataagagtg ttatcgagaa ggttcagaaa gacgggtatg ttcgtgtccg
    18481 tgtggatggg gaagtctatg atgtgaccga agtgccagag ttgtctaaga gcaagcaaca
    18541 caatatcgat gtcgtggttg accgtattgt tatcaaggag ggcattcgta gtcgtctctt
    18601 tgattccatt gaggctgccc ttcgtattgc agaaggttat gtcattatcg acaccatgga
    18661 caactctgag ttgttgttct ctgagcatta tgcctgtcca gtttgtggtt ttactgtccc
    18721 agagttagag cctcgtctct tttctttcaa tgctcctttt ggctcttgta gtgagtgtga
    18781 cggcttgggc atcaagctgg aggtggatac tgatttggta gtgccaaatg ccagcaaaac
    18841 cttacatgag ggagcgctgg caccttggaa tcctatctca tccaactact atccaaacat
    18901 gctagagcag gccatgacgg cttttggagt ggctatggat aagccttttg aggacttgtc
    18961 agaagaagac aagaacttga ttctctacgg ctcagatggt aagaaattcc atttccacta
    19021 tgagaatgaa tttggtggcg tgcgcgatat cgacattccg tttgagggag ttatcaataa
    19081 tatcaaacgt cgttaccatg aaaccaatag cgattacact cgcactcaga tgcgcctcta
    19141 catgaatgag ctgacttgcg gaacctgtca cggttatcgt ctcaatgacc aggccttgtc
    19201 tgtccgtgtg ggtggtgagc aagggccaca tatcggagaa atttcagacc tgtctatcgc
    19261 agatcacttg gacttggtga gccagttaac tttgtctgaa aatgaagcca tcattgctcg
    19321 tcccattctc aaggaaatca aggatcgttt gaccttcctt aataatgtgg gtcttaacta
    19381 tctaaccctg tcacgttcag caggaaccct ttcaggtggg gaaagtcagc gcattcgttt
    19441 ggcaacccag attggttcca acctatcagg cgtcctctat atcctagacg agccgtcaat
    19501 cggtcttcac cagagagaca atgaccgcct gattgccagt ctgaaaaaga tgcgtgactt
    19561 gggcaatact cttatcgtgg tggaacacga cgaagatacc atgcgtgaag ctgattatct
    19621 gattgacgtt ggtcctggtg ccggtgtttt tggtggtgag attgttgcag caggtacacc
    19681 taagcaagtg gctcgcaaca gcaagtctat cacaggtcag tacttgtcag gcaaacgtgt
    19741 catcccagta ccagaagagc gccgtgtcgg aaatggtcgt tttattgaag tgataggagc
    19801 gcgtgagaac aacttgcaaa atgtcacggc tcgctttcca ctaggaaaat ttatcgcagt
    19861 gacaggtgtg tcgggttcag ggaaatcgac tctaatcaac agcattctca aaaaagccat
    19921 tgcccagaag ctcaaccgta attcagacaa acctggtaag tttaagacta ttacagggat
    19981 tgagcatgtc gaccgtttga ttgatattga ccagagccct atcggacgga cgccgaggtc
    20041 taacccagct acctatacag gagtttttga cgatatacgt gacctttttg ctcagacaaa
    20101 tgaagccaag attcgaggct acaagaaggg acgcttcagt ttcaacgtca agggaggtcg
    20161 ctgtgaagct tgctcaggtg acgggattat caagattgag atgcacttct tgccagatgt
    20221 ttatgtggct tgtgaagttt gccacggaac ccgctataac agtgaaaccc tagaagttca
    20281 ctacaaggaa aagaatattt cgcaggtctt ggatatgacg gtcaacgatg cggtagaatt
    20341 tttccaacac attccgaaaa ttcaacgcaa actccagacc atcaaggatg tagggctagg
    20401 ctatgtgacc ttgggacagc cagctaccac cctttctggg ggagaagccc aacgtatgaa
    20461 gttagctagc gaactccaca aacgctcgac aggaaaatct ttctacattc tggatgaacc
    20521 gacgacaggg cttcatacag aggacattgc tcgcctgctc aaggttttag ctcgctttgt
    20581 agacgatggc aatacagtcc tcgtcatcga gcacaatctg gatgttatca agacggcaga
    20641 ccatatcatt gacttgggac ctgagggcgg tgtcggtggt ggaaccatca tcgtaacagg
    20701 aactccagaa gaagtagctg ccaacgaagc cagctataca ggacactatt tgaaaggaaa
    20761 gttacatcat gaataaacgc gtacaagcat ttctagctaa aatgcaagaa aaagaactag
    20821 atggtgtcat catcaacaat cttaaaaacg tctattattt gactggtttt tggggctcaa
    20881 acggaacagt ctttatcagc cgtgaccgtc aggtattagt gacagactct cgctatatca
    20941 tcgcagctaa gcaagaaacc agtggttttg agattgtggc tgatcgtgat gaattggctg
    21001 tcattgcagg aattgttaag gacatgggct tgactcgtat cggttttgaa gatgagattt
    21061 cagtgtctta ttaccaccgt atgcaggcag cttttgcagg tttgaacttg cttccacaaa
    21121 ctcagtttgt ggaaggtctt cgtatgatta aggatgaggc agagattgca gcgattcgca
    21181 aggcttgttc tatctcagac caagctttcc gcgatgcgct tgactttatc aaaccaggaa
    21241 aaactgaaat tgagattgcc aacttccttg atttccgcat gcgtgagttg ggagcatctg
    21301 gcttatcttt tgatacgatc ctagctagcg gtatcaattc ttctaaaccc catgcccatc
    21361 caatgcacaa accagtggag ttgggagaag ccattaccat ggacttcggc tgtctctatg
    21421 accactatgt cagtgatatg acccggacta tctatctagg gcatgttagc gatgagcagg
    21481 cagagattta caatacggtt ctaaaagcta accaagcctt gattgaccaa gctaaggcag
    21541 gcttaggttt ccgtgacttt gacaaaatcc ctcgtgatat tatcattgag gcaggttatg
    21601 gtgactactt tactcacggc attggccacg gtattggtct ggatatccat gaggaaccct
    21661 actttagtca gacttctaca gaaactatta agacaggtat ggccttgacc gatgaaccag
    21721 gtatctatat cgaaggcaaa tatggcgttc gtatcgagga tgatatcctg attacagaga
    21781 caggttgtga attattgacc ctagctccaa aagagttgat agtcatttag ttgtttgtca
    21841 agaaaaaagt acgaaaatga cgaaaaaagt caaaaaaaat t
//
LOCUS       DAVBEM010000037        21460 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVBEM010000037 DAVBEM010000000
VERSION     DAVBEM010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21460
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.037"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            66..287
                     /locus_tag="VQ548_001439"
     CDS             66..287
                     /locus_tag="VQ548_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2654277.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLELTDFPDKIRFRK"
     gene            804..1043
                     /locus_tag="VQ548_001440"
                     /pseudo
     CDS             804..1043
                     /locus_tag="VQ548_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            1187..2416
                     /locus_tag="VQ548_001441"
     CDS             1187..2416
                     /locus_tag="VQ548_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET2654278.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            2436..5132
                     /gene="ppc"
                     /locus_tag="VQ548_001442"
     CDS             2436..5132
                     /gene="ppc"
                     /locus_tag="VQ548_001442"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HET2654279.1"
                     /translation="MSLQKLENSSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATNLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYEIILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    5215..5432
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5545..6549
                     /locus_tag="VQ548_001443"
     CDS             5545..6549
                     /locus_tag="VQ548_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2654280.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     IELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTIKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            6618..7484
                     /locus_tag="VQ548_001444"
     CDS             6618..7484
                     /locus_tag="VQ548_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2654281.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            7481..8239
                     /locus_tag="VQ548_001445"
     CDS             7481..8239
                     /locus_tag="VQ548_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2654282.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            8329..10089
                     /gene="dnaG"
                     /locus_tag="VQ548_001446"
     CDS             8329..10089
                     /gene="dnaG"
                     /locus_tag="VQ548_001446"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HET2654283.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            10092..11201
                     /gene="rpoD"
                     /locus_tag="VQ548_001447"
     CDS             10092..11201
                     /gene="rpoD"
                     /locus_tag="VQ548_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HET2654284.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            11215..11544
                     /locus_tag="VQ548_001448"
     CDS             11215..11544
                     /locus_tag="VQ548_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET2654285.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            11659..12702
                     /gene="cpoA"
                     /locus_tag="VQ548_001449"
     CDS             11659..12702
                     /gene="cpoA"
                     /locus_tag="VQ548_001449"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HET2654286.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            12718..14043
                     /locus_tag="VQ548_001450"
     CDS             12718..14043
                     /locus_tag="VQ548_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2654287.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGILIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGALYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFRTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            14074..14250
                     /locus_tag="VQ548_001451"
     CDS             14074..14250
                     /locus_tag="VQ548_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET2654288.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            14309..14443
                     /locus_tag="VQ548_001452"
     CDS             14309..14443
                     /locus_tag="VQ548_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HET2654289.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            14507..15817
                     /gene="obgE"
                     /locus_tag="VQ548_001453"
     CDS             14507..15817
                     /gene="obgE"
                     /locus_tag="VQ548_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HET2654290.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            15827..15985
                     /locus_tag="VQ548_001454"
     CDS             15827..15985
                     /locus_tag="VQ548_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654291.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            17035..18294
                     /locus_tag="VQ548_001455"
     CDS             17035..18294
                     /locus_tag="VQ548_001455"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET2654292.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            18310..18861
                     /locus_tag="VQ548_001456"
     CDS             18310..18861
                     /locus_tag="VQ548_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2654293.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            18854..20131
                     /locus_tag="VQ548_001457"
     CDS             18854..20131
                     /locus_tag="VQ548_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2654294.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIDRLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            20147..21007
                     /locus_tag="VQ548_001458"
     CDS             20147..21007
                     /locus_tag="VQ548_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HET2654295.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            21230..21340
                     /locus_tag="VQ548_001459"
                     /pseudo
     CDS             21230..21340
                     /locus_tag="VQ548_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818216.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase"
BASE COUNT         6560 a         3686 c         4816 g         6398 t
ORIGIN      
        1 ccagttagga cactttgaat gatttcttag ttttatatat tatacttttc tcaggagaaa
       61 gctagatgta cagacgtttg agagatttga gggaagatca cgatttgacc caaaaacaaa
      121 tagctaaaat actttcgttt acaaactcag cttatgctaa aattgaacgg ggtgagcata
      181 cgttaacagc agatgtattg gtaactctct caaactttta cgatgtcagt acagactacc
      241 tattggaatt gacagatttt cctgataaaa ttcgctttag aaaataatct cctcaatttc
      301 atagagtgtg aaaatgagga gattttttat ttgttctttg aaaattaaat agtccaaaat
      361 ggtactttcc tcatttgtgg agcaaatttg aatggctcgc catgataaga gcgattttaa
      421 agccatcaat aaaatagagc gatactttat atgccatgat acaaatgata tacaatgata
      481 cttctgaccg ttcaggctgc catcgtaaaa gagcagcaag tgaaattctt atgatgactt
      541 catcagtcat gccacgttga atgtgtgagt ttgttagaga aacgcaatta atcctcaaaa
      601 ggttccccga accttttgag ttccacagac gcatcacgtg gagtgtgtaa gcttgttgct
      661 aaaagcgtaa aaaccttgga acgaaaggaa taatagactt cctgcgaaac aaaaatacaa
      721 tacaataaaa ctatggatga tgaagcaagt aaacaattaa gcgatagccg tttcaagagc
      781 cttgtaggtg ttcagcgcac gagatgttag ctgtgttaaa aacagcttat caacgcaacg
      841 taaacgcgca aaaggtggac gaaaaaccaa attaagccta gacgatctcc tcatggtaac
      901 tattcaatac atgcgagaat agcgcactta tgaacaaatt gcggctgatt ttggcattca
      961 cgaaagcaac ataattagtc ggaggtcaat ggattgaagc aactcttatt caaaatggtt
     1021 ttacgatttc aaattctgcc ttaattctgt aaaaacagta aaattcgaag gattgtaagg
     1081 taagagtttt tttctttctg aaaaaatggt ataatagcaa tcaaaactag aaaataaaac
     1141 ggaatttgga acagatttgt ctgtatccta gtagagtggt gatactatga agattagtaa
     1201 gaggcactta ttaaattatt ccatcttgat tccctacttg cttttatcta ttttgggctt
     1261 gattgtggtc tattcgacca ccagtgctat tttaattgaa gaaggcaaga gcgccttgca
     1321 gttggttcga aaccaaggaa tcttttggat tgttagtttg atactgattg ccttaattta
     1381 taaattgaga ctagattttt tgagaaatga gcgactaatc attttagtta tattaataga
     1441 aatgctttta ttgttcttgg ctcgttttat tggtatttca gtaaacgggg catacggttg
     1501 gatttcggtt gcaggagtaa ctattcagcc agctgagtac ttaaaaatca ttattatttg
     1561 gtatttagct caccgattct ccaaacagca agaagaaata gctacttatg attttcaagt
     1621 tttgactcaa aatcaatggc ttccccgtgc ttttaatgat tggcgattcg ttctcctagt
     1681 tctgattgga agtttgggaa ttttccctga tttaggaaat gcgactattt tagtcttggt
     1741 ttccttgatt atgtatacag ttagtggaat cgcttatcgc tggttttcaa ccattctggc
     1801 gctcgtatct gccgcttctg tctttgtctt gaccactatc agcctaatcg gtgttgagac
     1861 cttttcaaaa attccagtat ttggctatgt agccaaacgc tttagtgcct tttttaatcc
     1921 ttttgccgat cgtgctgatg caggtcacca gttagctaat tcttattttg ccatggtcaa
     1981 tggtggttgg tttggtctag gtcttggaaa ctcgattgaa aaacgaggtt atttgccaga
     2041 agctcataca gactttgtct tttctatcgt gattgaagaa tttggctttg ttggtgccag
     2101 tcttatttta gctctcttgt ttttcatgat tttgcggatt atcttggtcg gtattcgagc
     2161 ggagaatcct ttcaatgcca tggttgcact cggtgtcgga gggatgatgt tggttcaggt
     2221 atttgtcaat atcggaggga tttcgggctt gattccatct acaggagtaa ccttcccctt
     2281 cttatcccag ggtggaaata gtcttctagt cttatcagtg gcagtagcct ttgtcttaaa
     2341 tattgatgcc agtgaaaaac gcgctaagtt gtaccgagaa ttggaaaatc aaccaatgaa
     2401 ccttctgttg aagtaggata aagaaaggat agtttatgtc tcttcaaaaa ttagaaaatt
     2461 ctagtaataa aagtgttgtg caagaagaag tcttgattct aacagaatta ctggaagata
     2521 ttactaaaaa tatgcttgcc ccagagacct ttgaaaaaat aatacagttg aaagaattat
     2581 caacgcagga agattatcaa ggtctaaacc gtctagtgac tagcttatca aatgatgaaa
     2641 tggtctatat ttcacgctat ttctctatct tgcctctttt gattaatatt tcagaggatg
     2701 tggatttagc ttatgaaatc aatcatcaaa ataatattga tcaggactat ttaggtaaat
     2761 tatctacaac gattaaattg gtagcagaaa aggaaaatgc cgttgagatc ctagaacact
     2821 tgaatgttgt tccggttttg acagcccatc caacacaagt gcaacgcaaa agtatgttgg
     2881 atttaacaaa tcatattcat agtcttttgc gtaaataccg tgatgttaag ttggggttga
     2941 tcaataaaga taaatggtac aatgatttgc gtcgttacat cgaaattatc atgcagacag
     3001 acatgattcg tgagaaaaaa ttaaaagtga ctaacgaaat cacgaatgct atggaatatt
     3061 ataacagctc ctttttgaaa gctgtacctc atttgacgac ggagtataag cgcttagcgc
     3121 aagcgcatgg tctgaattta aaacaggcta aaccaatcac catgggtatg tggataggtg
     3181 gtgaccgtga tggaaatcca tttgttacag caaagacctt gaagcagtct gcactcactc
     3241 aatgtgaagt catcatgaac tactatgata aaaagattta ccaactttat cgtgaatttt
     3301 ctctttcaac tagcattgtc aacgtcagca agcaagtcag agaaatggct cgtcaatcca
     3361 aggataactc gatttaccgc gaaaaagagc tttaccgtcg tgccttgttt gatattcaat
     3421 caaaaattca ggcaactaaa acctatctga ttgaggatga agaagttggg actcgttatg
     3481 aaaccgccaa tgatttctac aaggatttga ttgccattcg agattctcta ctagagaata
     3541 agggcgagtc cttgatttca ggtgattttg tggaattatt gcaggcagta gagatatttg
     3601 gtttttacct agcatcaatt gatatgcgac aagactctag cgtctatgaa gcctgtgtgg
     3661 cagaactctt gaaatcagca ggaattcatt ctcgttatag cgagttgagc gaagaagaaa
     3721 agtgtgacct tcttttgaaa gaattagaag aagatccccg aattctttct gcgactcacg
     3781 cagaaaaatc agaattatta gcaaaagaac tagctatttt taagacggct cgtgttttga
     3841 aagataagtt gggagatgat gtcatccgtc agaccatcat ttcacatgca accaaccttt
     3901 ctgatatgct agaattagct attctgttaa aagaagtagg actggtggat acggaaaggg
     3961 cgcgtgttca gattgttccc ctttttgaaa caattgaaga cttggatcat tcagaggaaa
     4021 caatgagaaa atatctttct cttagccttg ccaaaaaatg gattgactca cgaaataact
     4081 accaagaaat catgcttggc tactctgaca gtaataaaga tggcggttac ttgtcatcat
     4141 gttggaccct ctacaaggct caacaacaat tgactgctat tggagatgaa tttggcgtta
     4201 aggttacctt cttccatggt cgtggtggta ctgtcggtcg tggtggtggg ccaacctatg
     4261 aagccattac atctcaaccg ctcaagtcta tcaaggatcg tatccgtttg acggagcagg
     4321 gtgaagtaat tgggaataaa tacggtaaca aagacgccgc ttactataac cttgaaatgc
     4381 tagtatcggc agctattaac cgtatgatta ctcagaagaa gagcgatacc aataccccaa
     4441 atcgttatga agccattatg gatcaagtag tggaccgtag ttacgatatc taccgtgatt
     4501 tggtctttgg taatgagcat ttctatgatt atttcttcga gtcaagtcca atcaaggcta
     4561 tttcaagttt taatattggt tctcgtccag ccgctcgtaa gactattact gaaatcggtg
     4621 gtttgcgtgc catcccttgg gtattctcat ggtcacagag tcgtgttatg ttccctggat
     4681 ggtacggggt tggttcaagc ttcaaggaat ttatcaataa aaatccagag aatattgcta
     4741 tcttacgaga tatgtaccaa aattggcctt tcttccaatc gcttctttca aatgttgata
     4801 tggttttgtc aaaatcaaat atgaatattg cttttgaata tgctaaactt tgtgaagacg
     4861 agcaagttaa ggccatctat gagattattt taaatgaatg gcaagttact aagaacgtta
     4921 tcttggctat tgaaggacat gacgaactct tagctgacaa tccatatcta aaagctagtc
     4981 tggattaccg tatgccttac tttaatattc tcaactatat tcagttagag ttgattaaac
     5041 gccaacgtcg tggagaattg tccagtgatc aagaacgatt gattcatatc accatcaacg
     5101 gaattgcgac aggattgcgt aattcaggtt gataattttc aagagtgaat gctaaaagtg
     5161 aatatcaaaa aaattctaat agactattga caagtagttt aaaaatgata taatttaacc
     5221 attcagaaaa gtaatcatac aaacttttta gagagtctgt ggtagctgaa aacagataag
     5281 tggcgatgat gaaaattggg ctgaatgcta tttagaattt gaaattataa aaattcggta
     5341 agcacacctt acagtgcatc tcgttattgc gagactgagc gatagggaaa ttccctataa
     5401 ttgaggtggt accgcgcatc gacgtcctca cacaagtttt ttgtgtgagg atttttttga
     5461 tggaggttag tatggaaaga aaacgatggc gtcgcttgtt tagataagtg aaatatgtta
     5521 aaggaaataa aaaggagaaa cagaatgaaa aataaacgtt taattggaat tattgctgca
     5581 ttagcagtct tagtagcagg aagcttgatt tattcttcaa tgaataaatc agaagctcag
     5641 aataataagg atgagaagaa aataaccaag attggtgtgc ttcaatttgt gagccatcca
     5701 tcccttgatt tgatttataa agggatccaa gatggacttg cagaagaagg atataaagat
     5761 gatcaagtta aaattgattt tatgaactca gaaggtgatc aaagtaaggt tgcgacaatg
     5821 agtaaacaat tggttgcaaa tgggaatgac cttgtggttg gtattgcaac accagcagcc
     5881 caagggttgg ctagtgcaac aaaagaccta ccagttatca tggccgctat tacagaccca
     5941 attggtgcta acttggttaa agatttgaaa aaaccaggtg gtaacgttac aggggtatct
     6001 gaccacaatc cagctcaaca acaaattgaa ctcatcaagg ctctgacacc gaatgtgaaa
     6061 acaatcggag ctctttactc aagtagcgaa gacaattcaa aaacacaggt tgaagaattt
     6121 aaggcttatg ctgaaaaagc aggtctgaca gtggaaacat ttgcagttcc ttcaacaaat
     6181 gaaattgcct caactgtcac tgttatgact atcaaggtag atgctatttg ggttccaatt
     6241 gataacacca ttgcatcagg atttccaacg gttgtctcta gcaatcaaag ttctaagaaa
     6301 ccaatttatc ccagtgcgac agctatggta gaagtaggtg gtttggcatc agttgtaatt
     6361 gaccaacatg accttggtgt ggcaacaggt aaaatgattg tgcaagtctt gaaaggtgca
     6421 aaaccagccg ataccccagt caatgtcttt tcaactggta agtcagtcat caataaaaaa
     6481 atagcacaag aactaggtat tactattcct gagtctgttc tcaaagaagc aggacaagtc
     6541 atcgaataaa taaggtaggg aggaggagac tcttcccatt ttttaaaaag atgaatatag
     6601 aaaggattaa ataaaatatg attgtttcca ttatttctca aggatttgtc tgggctattc
     6661 taggtctggg aatctttatg acatttagga ttttaaactt tccagatatg acgacagaag
     6721 gttccttccc tcttggggga gctgttgctg tcactttgat aaccaaaggc gtgaacccat
     6781 ttttagcgac acttgttgct gtaggagcag gttgtttggc tggaatggca gcaggccttc
     6841 tttatacaaa agggaagatc ccaaccttgc tctcagggat tttggtgatg acttcttgtc
     6901 actcaatcat gctcttgatt atgggacgtg cgaatttagg cctgcttgga accaagcaaa
     6961 ttcaggatgt tttgcctttt gattcggatt tgaatcaact cttgacaggt ctcatctttg
     7021 tgagcattgt tattgctctc atgctctttt tcttggacac taaactcgga caagcctata
     7081 ttgctacagg ggataatcct gatatggcta gaagtttcgg gattcatact ggacgcatgg
     7141 agctcatggg cttggtctta tcaaatggtg tgattgccct tgcaggtgcc ctcattgctc
     7201 agcaagaagg ctatgccgat gtgtctcgag ggatcggggt tatcgttgtg gggcttgcaa
     7261 gtttgattat tggagaagtt attttcaaga gtttgagctt ggcagagcgt ttggttacta
     7321 tcgttgtagg ttctatcgct tatcaatttt tagtgtgggc agttatcgca cttggcttta
     7381 atacaagtta ccttcgttta tacagtgcct tgattttagc agtctgcctc atgattccaa
     7441 catttaagca aacaatcttg aaaggagcca agttaagcaa atgacagcaa ttgtagaatt
     7501 aaaaaatgca accaaaattg ttaaaaatgg ctttgatgaa gaaaagatta ttttaaatga
     7561 tgtttcctta gaaatttttg aacgggactt tatcacgatt ttgggcggaa atggtgctgg
     7621 aaaatcaacc ctctttaaca ctatagcagg gaccttatca ctaactagtg gaactatccg
     7681 tattttaggt gaagatctca ctaagttttc acccgagaag cgtgccaagt acctgtctcg
     7741 tgtcttccaa gatccaaaga tggggacagc tccccgtatg acggtcgctg aaaatctttt
     7801 aatcgccaag tttcgtggtg agaagcgtgg attgttacca cgacgcttga ctagctataa
     7861 ggatgaattt caggcaacca ttgaaaaagt aggaaatggt cttgagaaac acttgaatac
     7921 accgattgag ttcttatcag gtggacaaag acaggctttg agtctcttga tggcaacctt
     7981 gaagcgacct gaattactcc tgttagatga gcatactgct gccctggatc caaagactag
     8041 tgttgctttg atggaattga cagatgaatt tgttaagaaa gatcagctaa cagcccttat
     8101 gattactcat catatggaag atgctctcaa atacggcaat cgcttgattg tcatgaaaga
     8161 aggacggatt atccaagatt taaaccaaga agaaaaagca aaaatgaaaa tctctgatta
     8221 ttatcaactc tttgaataaa gtagggaaaa tgagtgaaat ggtttacttt ttttctgaaa
     8281 taaagtatac tatataaagt aaactatgat aacatggagg tattgtgtat ggttgacaaa
     8341 caagtcattg aagaaatcaa aaacaatgcc aacattgtgg aagtcatagg agatgtgatt
     8401 tctttacaaa aggcaggacg gaactatcta gggctctgtc cttttcatgg tgaaaaaaca
     8461 ccttctttca acgttgtaga ggacaagcag ttttaccact gttttggttg tggtcgctca
     8521 ggtgatgtct ttaaattcat cgaggagtac caaggggtta cctttatgga ggctgtccaa
     8581 atcttaggtc agcgtgtcgg gattgaggtt gaaaaaccgc tttatagtga acagaagcca
     8641 gcctcgcctc accaagctct ttatgatatg cacgaagatg cggctaaatt ttaccatgct
     8701 attctcatga caacgactat gggcgaagag gccagaaatt acctttatca gcggggtttg
     8761 acagatgaag tgcttaaaca tttttggatt ggtttagcac ctccagaacg aaactatctc
     8821 tatcaacgtt tgtctgatca gtatcgtgaa gaggatttac tggattcagg cctgttttat
     8881 ctctcggatg ccaatcaatt tgtagacacc tttcacaatc gcattatgtt tcccctgaca
     8941 aatgaccaag gaaaggtcat tgccttctca ggtcgtatct ggcaaaaaac ggattcacaa
     9001 acttctaagt ataaaaacag ccgatcgact gcaattttta acaaaagtta cgaattatat
     9061 catatggata gggcaaaaaa atcttctgga aaaactagtg agatttacct gatggaagga
     9121 ttcatggatg ttattgcagc ctatcgggct ggaatcgaaa atgctgtggc gtcgatggga
     9181 acggccttga gtcgagagca tgttgagcat ctgaaaaggt taaccaagaa attggttctt
     9241 gtttacgatg gagataaggc tgggcaagcc gcgatattga aagcattgga tgaaattggt
     9301 gatatgcctg tgcaaatcgt tagcatgcct gataacttgg atcctgatga gtatctacaa
     9361 aaaaatggtc cagaagactt ggcctatcta ttaacaaaaa ctcgtattag tccgattgag
     9421 ttctacattc atcagtacaa acctgaaaac agtgaaaatc tgcaggctca gattgagttt
     9481 attgaaaaaa tagctccctt gattgttcaa gaaaagtcca ttgctgctca aaacagctat
     9541 attcatattt tagctgacag tctggcgtcc tttgattata cccagattga gcagattgtt
     9601 aatgagagtc gtcaggtgca aaggcagaat cgcatggaaa gaatttccag accgacgcca
     9661 atcaccatgc ctgtcaccaa gcagttatcg gctattatga gggcagaagc ccatctactc
     9721 tatcggatga tggaatcccc tcttgttttg aacgattacc gtttgcgaga agactttgca
     9781 tttgctacac ctgaatttca ggtcttatat gacttgcttg gccagtatgg aaatcttcct
     9841 ccagaagttt tagcagagca gacagaggaa gttgaaagag cttggtacca agttttagct
     9901 caggatttgc ctgctgagat atcgccgcag gaacttagtg aagtagagat gactcgaaac
     9961 aaggctctct tgaatcagga caatatgaga atcaaaaaga aggtgcagga agctagccat
    10021 gtaggagata cagatacagc cctagaagaa ttggaacgtt taatttccca aaagagaaga
    10081 atggagtaat aatggcaaca aaacaaaaag aagtaacaac atttgacgta caggtagcag
    10141 aatttatccg taatcataag caaaaaggga cagcaacaga tgatgaaatc aatgcaagtc
    10201 tggttattcc ttttaccttg gacgctgatg ggattgaaga tctcttgcaa cggattcagg
    10261 atgcagggat ttctatcaca gataacgaag gaaatccaag tgcgcgtgtt cttagcaatg
    10321 aagaagaacc agaactcagc gatgaggact tgattggatc aacttctgct aaggtcaatg
    10381 accctgtccg tatgtacttg aaagaaatag gggtcgttcc tctcttgacc aatgaagagg
    10441 agaaagagtt ggcactggct gttgaagctg gcgatatcga agccaaacaa cgtcttgcgg
    10501 aagccaatct tcgtttggtt gtttccattg ccaaacgcta tgtcggtcgt ggcatgcagt
    10561 tccttgactt gattcaagaa ggaaatatgg gcttgatgaa ggcggttgac aagtttgact
    10621 attctaaagg gttcaagttt tcaacttatg caacttggtg gattcgtcag gctatcactc
    10681 gtgctattgc ggaccaagct cgtaccatcc gtatcccagt tcacatggtt gaaactatca
    10741 ataaattggt tcgtgaacag cggaatctcc ttcaagaatt ggggcaagat ccgacaccag
    10801 aacagattgc tgaacgaatg gatatgacac ctgataaggt tcgtgaaatc ttgaagattg
    10861 cccaagaacc agtatctctt gaaactccta tcggtgaaga ggacgatagc caccttggag
    10921 actttatcga agatgaagtg attgaaaatc cagtggatta tacgactcgt atcgtcttgc
    10981 gtgagcaatt ggatgaaatc ttagatactc ttacagaccg tgaagaaaat gttctgcgtc
    11041 tacgttttgg actagatgat ggaaaaatgc gcacacttga agatgtgggg aaagtcttta
    11101 acgtaactcg tgagcgtatc cgtcagattg aagcaaaggc tttgagaaaa ctacgccaac
    11161 caagtcgcag caaaccgctt cgtgatttta ttgaagacta agagtgagga aaatatggct
    11221 tatacagaag agcaaattga aaacatcaaa acacggattt taacagcctt ggaagaagtc
    11281 atcgaccctg agttgggaat cgatattgtc aatcttggtt tgatctatga gattcgtttt
    11341 gacggtgaca cagggcaaac agagattgac atgactttga caactatggg ttgtccctta
    11401 gcagaccttt tgacagacca gatttatgat gctatgatag aggttccaga agtaacggat
    11461 actgaggtta aattagtctg gtatccagcc tggacagttg aaaaaatgag tcgctatgcc
    11521 cgcattgccc taggcattaa gtaaacatat aaaagcatgt gagagactag aggaaaagcg
    11581 aggaaatttc ccctcttttc ctctagtctc tcctttcttt tgctgatttt attcaaagaa
    11641 aatgatataa tagtagttat ggagaaaaag aaattacgca tcaatatgtt gagttcaagt
    11701 gagaaagtag caggacaggg agtttcaggt gcttaccgtg aattagttcg tcttcttcac
    11761 cgtgctgcca aggaccaatt gattgttaca gaaaatcttc caatcgaggc agatgtgact
    11821 cactttcata cgattgattt tccctattat ttatcaacct tccaaaagaa acgctcaggg
    11881 agaaagattg gctatgtgca tttcttgcca gctacacttg aaggaagttt gaaaattcca
    11941 tttttcttaa agggaattgt gaaacgctat gtattttctt tttacaaccg gatggagcac
    12001 ttggttgtgg tcaatcctat gtttattgag gatttggtag cagctggtat tccacgtgaa
    12061 aaagtgacct atattcctaa ctttgtcaac aaggaaaaat ggcatcctct accacaagaa
    12121 gaggtagtca gactgcgcac agatcttggt cttagtgaca atcagtttat cgtagtaggt
    12181 gctgggcaag ttcagaaacg taaagggatt gatgacttta tccgtctggc tgaggaattg
    12241 cctcagatta cctttatctg ggctggtggc ttctcttttg gtggtatgac agatggttat
    12301 gaacactata agaaaattat ggaaaatccc cctaaaaatt tgatttttcc aggcattgta
    12361 tcgccagagc ggatgcgcga attgtatgct ctagcggatc ttttcttgtt gcctagttac
    12421 aatgagctct ttcctatgac tattttagaa gctgcgagtt gtgaggctcc tattatgttg
    12481 cgtgatttag atctctataa ggtgattttg gagggaaatt atcgggcgac agcgggtaga
    12541 gaagagatga aagaggctat tttggaatat caagcaaatc ctgctgtctt aaaagatctc
    12601 aaagaaaagg ctaagaatat ttccagagag tattctgaag agcatctgtt acaaatctgg
    12661 ttggactttt atgagaaaca agccgcttta gggagaaagt aaaaagtgag gtaatctatg
    12721 cgaattggtt tatttacaga tacctatttt cctcaggttt ctggtgttgc gaccagtatt
    12781 cgaaccttga aaacagaact tgaaaagcag ggacatgctg tttttatctt tacgacgaca
    12841 gataaggatg tcaatcgcta cgaagattgg caaattatcc gcattccaag tgttcctttc
    12901 tttgctttta aggatcgtcg ctttgcctac cgaggtttta gcaaggcact tgaaattgct
    12961 aaacagtatc agctagatat tatccatact cagacagaat tttctcttgg cctgttgggg
    13021 atttggattg cgcgtgaatt gaaaattcca gtcatccata cctatcacac ccagtatgaa
    13081 gactatgtcc attatattgc taaggggata ttgatccggc cgagtatggt caagtatctg
    13141 gttagaggtt tcctgcatga tgtggatggg gttatttgcc ctagtgagat tgtccgtgac
    13201 ttgctatctg attataaggt caaggttgaa aaacgggtca ttcctactgg gattgaatta
    13261 gccaagtttg agcgtccgga aatcaagcag gaaaatttga aagaactgcg tagtaaacta
    13321 gggattcaag atggtgaaaa gacgttgctt agtctttcga gaatctccta tgaaaaaaat
    13381 attcaagcag ttttagcagc ctttgctgat gttctgaaag aggaagacaa ggttaaactg
    13441 gtagtagctg gggatggccc ttatctgaat gacctcaaag agcaagccca gaacctagag
    13501 attcaagact cagtcatctt tacagggatg attgctccta gtgagacggc tctttactat
    13561 aaagcggcgg atttcttcat ttcggcatcg acaagcgaaa cgcaaggttt gacctacttg
    13621 gaaagcttag ccagtggaac acctgtcatt gctcacggaa atccttattt gaacaacctc
    13681 atcagtgata aaatgtttgg agccttgtac tatggagaac atgatttggc tggtgctatt
    13741 ttggaagccc tgattgcaac accagacatg aatgagcata ccttatcaga gaaattgtat
    13801 gagatttcag ctgagaactt tgggaaacga gtgcatgagt tttatctgga tgccattatt
    13861 tcaaataact tccagaaaga tttggctaaa gatgatacgg tcagtcagcg tatctttagg
    13921 acagttttgt atcttccgca acaggtggtt gctgtacctg taaaaggatc tagacgcatg
    13981 ttgaaggctt caaaaacaca gttgatcagt atgagagact attggaaaga ccatgaagaa
    14041 tagaaagagg aacagctatg aaaaaaacaa ttaatgagaa gcggtcgtga taaaaagatt
    14101 gcgggtgttt gtgctggggt ggcccattat ctggatatgg atccgactat cgttcaagtc
    14161 atttggggtg ttcttacttg ctgttacgga gctggaattg tagcttacat tattttatgg
    14221 attatcgcac cagtagcaac tgactattga aaactagctc aattcatgct aagataatag
    14281 aaaatagaat gtaacgaagg agagaaaaat ggcatttgga gataatggaa atcgtaaaaa
    14341 aactatgttt gagaaaataa ccttgtttat cgtgattatc atgctagtag caagtttatt
    14401 gggaattttt gcaactgcaa ttggtgccct cagtaatcta taaaatagat tcaagaaaat
    14461 ttagtgactg ggatttccca gccctttttt aaagtgagaa gaaataatga gtatgttttt
    14521 agatacagct aagattaagg tcaaggctgg taatggtggc gatggtatgg ttgcctttcg
    14581 tcgtgaaaaa tatgtcccta atggaggccc ttggggtggt gatggtggtc gtggaggcaa
    14641 tgtggtcttc gttgtagacg aaggactacg taccttgatg gatttccgct acaatcgtca
    14701 tttcaaggct gattctggtg aaaaagggat gaccaaaggg atgcatggtc gtggtgctga
    14761 ggaccttaga gttcgagtac cacaaggtac gactgttcgt gatgcggaga ctggcaaggt
    14821 tttaacagat ttgattgaac atgggcaaga atttatcgtt gcccacggtg gtcgtggtgg
    14881 acgtggaaat attcgtttcg cgacaccaaa aaatcctgca ccggaaatct ctgaaaatgg
    14941 agaaccaggt caggaacgtg agttacaatt ggaactaaaa atcttggcag atgtcggttt
    15001 agtaggattc ccatctgtag ggaagtcaac acttttaagt gttattacct cagctaagcc
    15061 taaaattggt gcctaccact ttaccactat tgtaccaaat ttaggtatgg ttcgcaccca
    15121 atcaggtgaa tcctttgcag tagccgactt gccaggtttg attgaagggg ctagtcaagg
    15181 tgttggtttg ggaactcagt ttctccgtca catcgagcgt acacgtgtta tccttcacat
    15241 cattgatatg tcagctagcg aaggccgtga tccatatgag gattacctag ctatcaataa
    15301 agagctggag tcttacaatc ttcgcctcat ggagcgtcca cagattattg tagctaataa
    15361 gatggacatg cctgagagtc aggaaaatct tgaagaattt aagaaaaaat tgtctgaaaa
    15421 ttatgatgaa tttgaagagt taccagctat cttcccaatt tctggattga ccaagcaagg
    15481 tctggcaaca cttttagatg ctacagctga attgttagac aagacaccag aatttttgct
    15541 ctacgacgag tccgatatgg aagaagaagc ttactatgga tttgacgaag aagaaaaagc
    15601 ctttgaaatt agtcgtgatg acgatgcgac atgggtactt tctggtgaaa aactcatgaa
    15661 actctttaat atgaccaact ttgatcgtga tgaatctgtc atgaaatttg cccgtcagct
    15721 tcgtggtatg ggggttgatg aagcccttcg tgcgcgtgga gctaaagatg gggatttggt
    15781 ccgcattggt aaatttgagt ttgaatttgt agactaggag actggtatgg gagataaacc
    15841 gatatctttc cgagatgcgg atggtaattt tgtttccgcc gcagacgttt ggaatgaaaa
    15901 gaaattggaa gaactattta atcgtctcaa tccaaatcgt gccttgagat tggcacgaac
    15961 taaaaaggaa aatccatctc agtaaagaag ctaaaaaatc ccgtgcctca tcagacacgg
    16021 gattttgtgg tacgacaggc atgtatagca aactgaatct ggaatagcac agcatatctt
    16081 ctaaaatatt gttataaatt gatttgaatt tcaaaattaa attgtttgat tcttatctca
    16141 atttgttata gtatatctga tgtcaaagtt ctcggcgagt caaatagcga ttcccaagcc
    16201 tgactatcgt gaggtagcgg attaaaatgg tctggggata gaccgtttta agtctgacgc
    16261 tggaaataag aattgtcaga agaagggata gcgaaatcgt ggctctacga acaggaacgt
    16321 gataataagg cgtatatagc ggataagagg gcctcaaact ctaaagtcca aaaaggtagt
    16381 cgtaacctat atgcgtaaat cacgagagta attgaattcg tactaagatt ttctattttc
    16441 actgtaacct tttaacgtcc ttatatcttg tatacacgag gaaagatgta cgacttatcc
    16501 cgtgaggtct atcactataa agagaaaacg acagatagaa gtgatcctga gtcacggtta
    16561 tctttaaaat agattgtctg ataggacggt atgtataaaa cgcttctgtg aactgagaga
    16621 agggggagaa gttcttgcta aaatttagtt gaacagccgt attccgatac ttagataaga
    16681 gatctagtct tagctcctac tcagttttag gggataaaaa aggggaaata gcgattcgag
    16741 aaagattata ctcttcgaaa atctcttcaa atcacgtcaa tatcgccttg ccgtatgtgt
    16801 aggatactga ctacgtcagt tccatctaca acctcaaaac agtgttttga gcaacctgcg
    16861 gctagtttcc tagtttgatc tttgattttc attgagtatt agtaattcag ttactaactc
    16921 gtcaactctg atttatccaa taaaattgaa aaggatggaa aaaaggataa atttatgata
    16981 tactttattt tgaagacctt attagaaatc ttgaaagagt attgaaaact tagaatgaga
    17041 aaaattgtta tcaatggtgg attaccactg caaggtgaaa tcactattag tggtgctaaa
    17101 aatagtgtcg ttgccttaat tccagctatt atcttggctg atgatgtggt gactttggat
    17161 tgcgttccag atatttcgga tgtagccagt cttgtcgaaa tcatggaatt gatgggagct
    17221 actgttaagc gttatgacga tgtattggag attgacccaa gaggtgttca aaatattcca
    17281 atgccttatg gtaaaattaa cagtcttcgt gcatcttact atttttatgg gagcctctta
    17341 ggccgttttg gtgaagcgac agttggtcta ccgggaggat gtgatcttgg tcctcgtccg
    17401 attgacttac accttaaggc gtttgaagct atgggtgcca ctgctagcta cgagggagat
    17461 aacatgaagt tatctgctaa agatacagga cttcatggtg caagtattta catggatacg
    17521 gttagtgtgg gagcaacgat taatacgatg attgctgcgg ttaaagcaaa tggtcgtact
    17581 attattgaaa atgcagcccg tgaacctgag attattgatg tagctactct cttgaataat
    17641 atgggtgccc atatccgtgg ggcaggaact aatatcatca ttattgatgg tgttgaaaga
    17701 ttacatggga cacgtcatca ggtgattcca gaccgtattg aagctggaac atatatatct
    17761 ttagctgctg cagttggtaa aggaattcgt ataaataatg ttctttacga acacctggaa
    17821 gggtttattg ctaagttgga agaaatggga gtgagaatga ctgtatctga ggacagcatt
    17881 tttgtcgagg aacagtctaa tttgaaagca atcaatatta agacagctcc ttacccaggc
    17941 tttgcaactg atttgcaaca accgcttacc cctcttttac taagagcgaa tggtcgtggt
    18001 acaattgtcg atacgattta cgaaaaacgt gtaaatcatg tttttgaact agcaaagatg
    18061 gatgcggata tttcgacaac aaatggtcat attttgtaca cgggtggacg tgatttacgt
    18121 ggggccagtg ttaaagcgac cgacttaaga gctggggctg cactagtcat tgctgggctt
    18181 atggctgaag gtaaaactga aattaccaat atcgagttta tcttacgtgg ttattctgat
    18241 attatcgaaa aattacgtaa tttaggagcg gatattagac ttgttgagga ttaaaccgta
    18301 gaggtgttta tgaatatttg gaccaaatta gcaatgtttt ctttttttga aacggatcgc
    18361 ttgtatttgc gtcctttctt ttttagtgat agtcaggact tccgcgagat agcttcaaat
    18421 ccagaaaatc ttcaatttat tttcccaacg caggcaagtc tggaagaaag tcaatatgca
    18481 ctggccaatt actttatgaa gtcccctttg ggagtgtggg caatttgtga ccagaaaaat
    18541 caacaaatga ttggttctat taaatttgag aagttagatg aaatcaaaaa agaagctgag
    18601 cttggctatt ttttgagaaa agatgcttgg tcgcaaggat ttatgacaga ggttgttaga
    18661 aaaatttgtc agctttcttt tgaggaattt ggcttaaaac aattatttat cattacccac
    18721 cttgaaaatg aagctagcca aagagttgct cttaagtctg gatttagttt gttccgtcag
    18781 tttaagggaa gtgatcgtta cacaagaaaa atgcgggatt atcttgaatt tcggtatgta
    18841 aaaggagagt tcaatgagta agcatcagga aattctaagc tatttggagg aattaccagt
    18901 aggtaaaagg gtcagtgttc gtagcatttc gaatcatcta ggagttagtg atggaacagc
    18961 ctatcgagct attaaagaag ctgaaaaccg tggaattgtg gagacccgtc ctagaagtgg
    19021 aacaattcgt gttaaatccc agaaagttgc tatagataga ttaacgtttg ctgaaattgc
    19081 agaagtgact tcttctgagg ttctggctgg gcaagaaggt ttagagagag aatttagtaa
    19141 gttttcaatt ggtgccatga ctgaacaaaa tatcttgtct taccttcatg atggggggct
    19201 cttgattgtc ggagaccgaa cccgtattca gttgctagcc ttggaaaatg aaaatgcagt
    19261 tctggttaca gggggatttc aggttcatga tgatgtgctt aaactggcca atcaaaaagg
    19321 gattcctgtt ctaagaagta agcatgatac ctttaccgtc gctaccatga tcaataaagc
    19381 cttgtcaaat gtccaaatca agactgatat tctgacagtt gagaaacttt atcgccctag
    19441 tcatgagtat ggttttctga gagagacaga tacagttaaa gattatttgg acttggttcg
    19501 taagaatcgt agcagccgtt tccctgttat caatcaacat caggtcgttg ttggcgttgt
    19561 aaccatgaga gacgctggtg ataaatcacc aagcacgaca attgataagg ttatgtctcg
    19621 tagtctattt ttggttggat tatcgacaaa tattgccaat gtgagtcaac ggatgatcgc
    19681 agaagacttt gaaatggtac cagttgttcg aagcaatcaa actttgcttg gcgttgtgac
    19741 gcgacgagat gtcatggaga agatgagccg ttcccaagtt tcggctctac caactttttc
    19801 tgagcagatt ggacaaaagc tctcttatca ccatgatgaa gtagtcatta cagtggaacc
    19861 ctttatgcta gaaaaaaatg gagttttggc taatggtgta ttggcagaaa ttctgaccca
    19921 catgacccaa gatttagttg ttaatagtgg tcgcaatctc attatcgagc agatgctgat
    19981 ctactttttg caggccgttc agatagatga tatattgcgc attcaggcac ggattattca
    20041 tcatacgaga cggtcagcta taattgatta cgatatttat catggtcacc agattgtttc
    20101 aaaagcaaat gtgactgtta aaattaatta gaaactagga gaaaagatga taacattaaa
    20161 atcagctcgt gaaatcgaag ctatggacaa ggctggtgat tttctagcaa gtattcatat
    20221 aggcttacgt gatttgatta agccaggcgt agatatgtgg gaagttgaag aatatgtccg
    20281 ccgtcgttgt aaagaagaaa atttccttcc acttcagatt ggggttgacg gtgccatgat
    20341 ggactatcct tatgctacct gttgctctct taacgatgaa gtggctcacg ctttccctcg
    20401 tcattatatc ttgaaagatg gtgatttgct caaagttgat atggttttgg gaggtcccat
    20461 tgctaaatct gacctaaatg tctcaaaatt aaacttcaac aatgttgaac aaatgaaaaa
    20521 atacactcag agttattctg gtggtttagc agactcatgt tgggcttatg ctgttggtac
    20581 accgtccgaa gaagtcaaaa acttgatgga tgtaaccaaa gaagctatgt acaagggtat
    20641 tgagcaagct gttgttggaa atcgtatcgg tgatatcggt gcggctattc aagaatacgc
    20701 tgaaagtcgt ggttacggtg tagtgcgtga tttggttggt catggtgttg gcccaactat
    20761 gcacgaagaa ccaatggttc ctaactatgg tattgcaggt cgtggactcc gtcttcgtga
    20821 aggaatggtc ttaaccattg aaccaatgat caatacaggc gattgggaaa ttgatacaga
    20881 tatgaaaact ggttgggcgc ataagaccat tgacggtgga ttgtcatgtc agtatgaaca
    20941 ccaatttgtc attacgaaag atggacctgt tatcttgact agccaaggtg aagaaggaac
    21001 ttattaataa aaagtgaaaa gactactgga agtttattat gaaaaaatcc agtagatctt
    21061 ttcataataa aacgcattgt atcaagtgtt aggggctgat atcatgcgtt tttctgcttt
    21121 taagattttt tccaactctg tttgtaagcg catcataaca aagggtctag gattcagggc
    21181 tctcctccta tatactatta gtaaagtaaa actaagggag gatattttag tgtcgcagtc
    21241 tattgttcct gtagagattc cacaatattg tcgttttgat tctaaaaaga gaaatggaat
    21301 tctgtttaat gttcgtattg ccaatcttaa atttaccttt tttagattag acttcctgcg
    21361 aaacaaaaca tggtatagta gttctatgaa tgatgaagca agtaaacaac taactgatgc
    21421 acgatttaag cgtcttgttg gtgttcaacg cacgactttt
//
LOCUS       DAVBEM010000038        21102 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVBEM010000038 DAVBEM010000000
VERSION     DAVBEM010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21102
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.038"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            <1..266
                     /locus_tag="VQ548_001460"
     CDS             <1..266
                     /locus_tag="VQ548_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET2654296.1"
                     /translation="SIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGW
                     GDHYQLVAQKSVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            720..1413
                     /locus_tag="VQ548_001461"
                     /pseudo
     CDS             720..1413
                     /locus_tag="VQ548_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809626.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            1469..1741
                     /locus_tag="VQ548_001462"
     CDS             1469..1741
                     /locus_tag="VQ548_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase"
                     /protein_id="HET2654297.1"
                     /translation="MFLLFSALVGMLSQLKEVPESVFLQETVEENHLVNVYSVLEVIS
                     TLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK"
     gene            2055..2186
                     /locus_tag="VQ548_001463"
     CDS             2055..2186
                     /locus_tag="VQ548_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HET2654298.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            2207..3757
                     /gene="dltA"
                     /locus_tag="VQ548_001464"
     CDS             2207..3757
                     /gene="dltA"
                     /locus_tag="VQ548_001464"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HET2654299.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFVQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMIMDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGVTHFYFDG
                     EELTVKTAQKLRKRFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            3754..4998
                     /gene="dltB"
                     /locus_tag="VQ548_001465"
     CDS             3754..4998
                     /gene="dltB"
                     /locus_tag="VQ548_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HET2654300.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            5012..5251
                     /gene="dltC"
                     /locus_tag="VQ548_001466"
     CDS             5012..5251
                     /gene="dltC"
                     /locus_tag="VQ548_001466"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HET2654301.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            5244..6512
                     /gene="dltD"
                     /locus_tag="VQ548_001467"
     CDS             5244..6512
                     /gene="dltD"
                     /locus_tag="VQ548_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HET2654302.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            6667..7107
                     /gene="adcR"
                     /locus_tag="VQ548_001468"
     CDS             6667..7107
                     /gene="adcR"
                     /locus_tag="VQ548_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HET2654303.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            7107..7811
                     /locus_tag="VQ548_001469"
     CDS             7107..7811
                     /locus_tag="VQ548_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET2654304.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNTHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            7804..8610
                     /locus_tag="VQ548_001470"
     CDS             7804..8610
                     /locus_tag="VQ548_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET2654305.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGRSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            8620..10125
                     /gene="adcA"
                     /locus_tag="VQ548_001471"
     CDS             8620..10125
                     /gene="adcA"
                     /locus_tag="VQ548_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HET2654306.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKVTFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(11245..12018)
                     /locus_tag="VQ548_001472"
     CDS             complement(11245..12018)
                     /locus_tag="VQ548_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2654307.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPDQKLLDAVELFDGEWVSDIQ"
     gene            12194..13597
                     /locus_tag="VQ548_001473"
     CDS             12194..13597
                     /locus_tag="VQ548_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HET2654308.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            13712..14350
                     /locus_tag="VQ548_001474"
     CDS             13712..14350
                     /locus_tag="VQ548_001474"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HET2654309.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            14362..14802
                     /locus_tag="VQ548_001475"
     CDS             14362..14802
                     /locus_tag="VQ548_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HET2654310.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            14795..15226
                     /locus_tag="VQ548_001476"
     CDS             14795..15226
                     /locus_tag="VQ548_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2654311.1"
                     /translation="MFNRGILVASHGDFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISNYDSKINLEEIVHNAQNSLFNVKQQLNVEEEENLCL"
     gene            15217..15687
                     /locus_tag="VQ548_001477"
     CDS             15217..15687
                     /locus_tag="VQ548_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2654312.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            15712..16485
                     /locus_tag="VQ548_001478"
     CDS             15712..16485
                     /locus_tag="VQ548_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2654313.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            16482..17282
                     /locus_tag="VQ548_001479"
     CDS             16482..17282
                     /locus_tag="VQ548_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2654314.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            17341..19635
                     /locus_tag="VQ548_001480"
     CDS             17341..19635
                     /locus_tag="VQ548_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET2654315.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPVNLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            19645..>21102
                     /locus_tag="VQ548_001481"
     CDS             19645..>21102
                     /locus_tag="VQ548_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654316.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLH"
BASE COUNT         6542 a         3447 c         4467 g         6646 t
ORIGIN      
        1 ccagcataga tgagcgcttg cgtactcgcc tacgagtgat tatctggaag caatggaaga
       61 agaaatcgag acgattatgg ggattgctta agttaggagt tcctaaatgg atagcagata
      121 aggtatctgg ctggggcgac cattatcaat tagtagctca gaagtcggta cttaaacgtg
      181 ctatatcaaa accagtcctg gaaaaacgtg gactggtttc gtgtttggat tattaccttg
      241 aacgacatgc gttaaaagtt agttgaaccg ccgtatgccg aacggcacgt acggtggtgt
      301 gagaggggct agagattatc ctctactcga ttaactcccc tgaaatttgt tttaattatg
      361 caaatttcac gtatttttga tgctgagacg acgatcctgg gaacttttca gatatttttt
      421 tgactatcta aaatctatca ttagaaaagc ttagagcgcc aaaggatttg agcgtttttc
      481 tgatttttaa gactttttcc cagtctcttt ttcgattgaa gatgtaatta ttctactaac
      541 taacttctta gtactagcca acaacgataa tcataattcc tcctaaaatt aggaataata
      601 aaggcaatag tttttgtttt ttcatgtaaa aaacctcact tttgttttct gctattttat
      661 gctaaaatat taaaaatcaa atttaattcc aaagtttgta actaaagggg gagcgctaca
      721 tgtctaattc atttgtcaag ttgttagtct ctcaattatt tgcaaattta gcagatattt
      781 tctttagagt aacaatcatt gctaacatat acattatttc aaaatcagta attgccacat
      841 cactagttcc tatcttaata ggaatatcct cttttgttgc gagtctttta gttccgttgg
      901 ttactaaaag gttagcgcta aatagggttt tatctttatc tcaatttgga aagactatat
      961 tattggcgat actggtagga atgtttaccg taatgcaatc cgtagcgcct ttggtgacct
     1021 atctatttgt tgttgcaatt tccatactag atggttttgc agcacccgtt tcctatgcta
     1081 ttgtgccacg ctatgcgacc gatttgggta aggctaattc agccttatca atgactggtg
     1141 aagctgttca attgataggt tggggattag gtggactctt gtttgcaaca attggtctgt
     1201 tacctaccac gtttatcatt ttagtcttgt atatcatttc tagctttctg atgttatttc
     1261 ttcctaacgc tgaagtggag gtgttagagt cagaaactaa tcttgaaatt ttgctcaaag
     1321 gttggaagtt agttgctaga aatcctagat taagactttt tgtatcagca aatttattgg
     1381 aaattttttc aaatacgatt tgggtttctt ccattttgta gctatggcaa tagtgacact
     1441 gactattcta tattttccaa acgcacagat gtttttatta ttttcagctt tagttggtat
     1501 gttatcgcaa ctaaaagaag ttcctgaaag tgtatttctt caggaaacag tagaggaaaa
     1561 tcatttagtt aatgtctatt ccgttcttga agtgatttct acattagcat tttcagtatt
     1621 tgttttgcta atgagctata ttactgagag ttttggtatt agcatcagtt tttggctatc
     1681 agccatttgt ctgatgatag aagctatttt aatttatatc agacgagatt attttaaatg
     1741 agagagtggt taaaaagtct ttaaaaatca gaaaagcgca tagtatcagg tgttgaaaaa
     1801 acttgatatt gtgtgtttta ttatgggaag atttacttca ttgtctcctg aaatggagtt
     1861 ttgaagcagg atcactctat ttgaaaatat acatagaaaa actgtataat ccttaaaata
     1921 agctgaaatc tattggaaac atacggtaaa caattgaaaa ggtactatat aaagtggtac
     1981 aatggtagaa aaataagcta gtaagaatca ctcttatttt agcgaaaaat tacagaaatg
     2041 aatggttttt cttgatgaaa cagagaaaag aattgtacct ctttcttggt cggacagcct
     2101 tgtattttct tatctttcta gggctgcttt acttctttag ctatcttggt cagggtcaag
     2161 gaagctttat ctataatgaa ttttaacttg aaggagaatc cctattgtgt caaataaacc
     2221 aatagcagat atgattgaaa ccattgagca ttttgctcag acacagccta gctatcctgt
     2281 ctataatgtt ttggggcagg aacacactta tggcgattta aaggctgatt cggatagttt
     2341 ggctgcagtc attgaccaac taggcttgcc tgagaagtct cctgtggttg tttttggtgg
     2401 ccaagaatat gaaatgttgg caacctttgt agcgctgact aagtcaggtc atgcctacat
     2461 tccaattgat agccattcgg ccttggagcg agtttcagct attttagaag tagcagagcc
     2521 aagcttgatt attgccattt cagcctttcc cttggagcag gtttctacac caatgataaa
     2581 tctagctcag gttcaagaag cctttgttca agggaataac tatgaaatca cgcatccagt
     2641 caagggagat gataattact acattatctt tacttctggt acgactggta agcctaaggg
     2701 agtgcagatt tcacatgata atctcctcag ctttacaaac tggatgatta tggataagga
     2761 atttgcgaca ccgagtcgtc cgcaaatgct ggcacagcca ccttattctt ttgacttgtc
     2821 tgtcatgtat tgggcaccga ccttggcact tggtggtacg cttttcactc ttccttcagt
     2881 catcactcag gactttaagc aactctttgc ggctatcttt tcattgccaa tcgctatctg
     2941 gacatcaaca ccatcctttg cagatatggc catgttgtct gaatacttca acagtgagaa
     3001 aatgcctgga gtcacgcatt tctactttga tggtgaagaa ttgacggtca aaacagctca
     3061 aaaactgcgc aagcgtttcc caaatgcccg tatcatcaat gcttacggcc caacagaagc
     3121 gacagtagct ctgtcagcag ttgccgtgac agacgagatg ttagcgactc tcaaacgcct
     3181 accaatcggc tataccaagg ctgattctcc aacctttatc attgacgagg aaggaaataa
     3241 actgccaaat ggcgaacagg gagaaatcat tgtttctggg ccagctgttt caaaaggtta
     3301 tatgaacaat cctgaaaaaa cagcagaagc cttctttgag tttgaaggtc tgccagccta
     3361 tcacacaggc gatgtgggaa ccatgacaga tgagggcttg cttctctacg gcggacgcat
     3421 ggacttccag attaagttta acggttaccg cattgagtta gaagatgtct ctcaaaacct
     3481 caacaagtct cgctttatcg aatctgctgt cgcagtaccg cgctataaca aggaccacaa
     3541 ggtacaaaat ctattggctt atgtcatctt aaaagacggt gttcgtgagc agtttgagcg
     3601 agatatcgat attaccaagg ccatcaagga agacctgaca gacatcatga tgtcctatat
     3661 gatgccatct aaattccttt accgagacag tttgccactg actccaaatg gaaagattga
     3721 catcaaagga ttgattaacg aggtgaataa gagatgatgg agttttttca acagcttcct
     3781 catttagagc catatggcaa tcctcagtat tttgtttatg tgattgctgc aaccttgccc
     3841 atctttatag gtctcttttt caagaaacgc tttgcctggt atgaagtgtt ggtaagtctc
     3901 ttctttattg tcaccatgtt ggtgggtgga aagaccaatc aactagctgc cttgggtatt
     3961 tacctttgct gggaaatatt gctcctgctt ttctacaagc attatcgaaa aagcaaggat
     4021 ggcaagtggg tcttctactt agttagtttt ctgtccctac ttccgattat ctttgtcaag
     4081 gtgcaaccag ctatcaatgg aacgcagtct ttgcttgggt tcttgggaat ttcttatctt
     4141 acctttcgtt cggttgggat tatcatcgag ctgagagatg gagtgattaa ggattttacc
     4201 ctctgggaat tcctccgttt ccttctcttc atgccaactt tctcgagtgg tccaatcgat
     4261 cgctttaagc gatttaatga aaattatcag gctattcctg agcgagatga gttgatggat
     4321 atgctggatg aatctgtccg ctatatcatg tggggctttt tgtataagtt tatcctagct
     4381 catgttttag gagagacctt actacctcct ctgaagaatt tagccttgca gtcaggtggc
     4441 ttctttaatc tctatgcctt ggcagttatg tatacttttg gtctggagct cttctttgac
     4501 tttgcaggtt attctatgtt tgctttggcc atctcaaact tgatgggaat ccgtagccct
     4561 atcaacttta acaagccctt tttatcaagg gatttaaagg agttttggaa tcgctggcat
     4621 atgagtctgt ccttctggtt ccgtgacttt gtctttatgc gaatggtgat ggtgttaacc
     4681 agaaagaaag tctttaaaaa tcgtaatgta acctcaagca tggcctacat tgtaaatatg
     4741 ctgattatgg gattttggca tggtgtgacc tggtactata tcgcctatgg actctttcat
     4801 ggactaggct tggtcatcaa tgatgcctgg gttcgcaaga aaaaaacact caataaggaa
     4861 cggaaaaaag cagggaaggc tgccctacct gagaatcgct ggattcagtt gcttggcatg
     4921 gttgtcactt tccatgttgt catgttgtca ttcttaatct tttctggatt cttgaataat
     4981 ctatggttta aaaaataaaa ggaaataaaa tatggatatc aaatcagaag ttatcgaaat
     5041 tattgatgag ttgtttatgg aagatgtttc tgacatgatg gatgaagatc tttttgatgc
     5101 aggtgtcttg gatagtatgg gaacggttga gttgattgtg gagattgaga accgttttga
     5161 cattcgtgtc cctgtaacag agtttggtcg tgacgactgg aatacagcta ataaaatcat
     5221 agctggtatt gtggagctac aaaatgctta aacgcttatg gatgatcttc ggaccggtct
     5281 tgatcgctgg tttgttggtt tttctgctca ttttctttta tcctactgag atgcatcata
     5341 atctaggagc tgaaaagcgt tcagcagtgg ctactactat cgatagtttt aaggagcgaa
     5401 gtcaaaaagt cagagcacta tctgatccaa atgtgcgttt tgttcccttc tttggctcta
     5461 gtgaatggct tcgttttgac ggtgctcatc ctgcggtatt agctgagaaa tacaatcgtt
     5521 cctaccgtcc ttatctttta ggacaggggg gagctgcatc gcttaaccaa tattttggaa
     5581 tgcaacagat gttaccacag ctggagaata aacaagttgt gtatgttatc tcacctcagt
     5641 ggttcagtaa aaatggctat gatccagcag ccttccagca gtattttaat ggagaccagt
     5701 tgactagttt tctgaaacat caatctgggg atcaggctag tcaatatgca gcgactcgct
     5761 tactgcaaca gttcccaaac gtagctatga aggacctggt tcagaagttg gcaagtaaag
     5821 aagaattgtc gacagcagac aatgaaatga ttgaattatt ggctcgtttt aatgaacgcc
     5881 aagcttcctt ttttggtcag ttttcggtta gaggctatgt taactacgat aagcatgtag
     5941 ctaagtattt aaaaatcttg ccagaccagt tttcttatca ggcaatagaa gatgttgtca
     6001 aagcagatgc tgaaaaaaat acttccaata atgagatggg aatggaaaat tatttctata
     6061 atgagcagat caagaaggat ttgaagaaat taaaggattc tcagaaaagc tttacctatc
     6121 tcaagtcgcc agagtataat gacttgcagt tggttttaac acagttttct aaatctaagg
     6181 taaacccgat ttttatcatt ccacctgtta ataaaaaatg gatggactat gctggtctac
     6241 gagaggatat gtaccaacaa acggtgcaga agattcgcta ccagttagaa agtcaaggtt
     6301 ttaccaatat agcagatttt tctaaggacg gcggggagcc tttctttatg aaggacacca
     6361 ttcaccttgg ttggttgggt tggttggctt ttgacaaggc agttgatcct ttcctatcca
     6421 atcccacacc agctccgact taccatctga atgagcgctt tttcagcaaa gattgggcga
     6481 cttatgatgg agatgtcaaa gaatttcaat agataatata atatagaaga gttcaagaat
     6541 gaaactagtt ttcacgtttt ttcttgactc tttttttgct tgtgatataa ttaactggta
     6601 aacaaaatgt caaagaatag tatttttctc ttaaaaaaga gaagtctaaa aggaaaggag
     6661 tcagatatga gacagctagc aaaggatatc aatgcttttt tgaatgaggt gattttgcag
     6721 gcggaaaatc agcatgaaat cctaataggt cattgcacta gcgaggtggc cctgaccaat
     6781 actcaggagc atatccttat gctcttgtca gaggaatctt taacaaattc agaattggcc
     6841 cgtcgtctca atgtcagtca ggcggcagtt accaaggcca ttaagtcttt ggtcaaggaa
     6901 gggatgttgg aaacatctaa agattctaaa gatgcgcgtg tgatttttta tcagttgact
     6961 gacttggctc gtccaatcgc tgaggagcac caccatcacc atgagcatac acttttaacc
     7021 tatgaacaag tggcgactca gtttactcca aatgaacaaa aagtgattca gcggtttttg
     7081 actgctttag taggagaaat caaataatga gatatattac ggtagaggat ttgtccttct
     7141 attatgataa ggaacctgtt cttgaacata tcaattattg tgttgatagt ggggaatttg
     7201 ttaccttgac tggggaaaat ggagcggcta agacgacgct catcaaggcc agtcttggaa
     7261 ttctgcaacc acgcattgga aaggtggcta tttcaaagac aaatacgcaa ggtaagaaat
     7321 tgagaatagc ctatcttcct caacaaattg ccagttttaa tgctggtttt ccaagtacgg
     7381 tctatgaatt tgtcaagtcg ggtcgctatc cgagaaaagg ctggttccgt cgtttgaata
     7441 ctcatgatga ggagcatatc aaggctagtc tggactcagt tggcatgtgg gaacatcgag
     7501 acaaacgctt ggggtctcta tctgggggac aaaagcagcg agcggtaatt gcgcgtatgt
     7561 ttgcttctga ccctgatgtg tttatcctag acgagccgac aacggggatg gatgcaggaa
     7621 gtaaaaatga attttacgaa ctcatgcacc acagcgccca tcatcatggc aaggctgttt
     7681 tgatgattac ccatgaccct gaagaagtta aggattatgc ggatcgcaat attcatctag
     7741 tccgtaacca agactcgcca tggcgttgtt tcaacgttca tgagaatggg caggaggtgg
     7801 gccatgctta gtttattatc ttacgacttt atacaacgcg cctttttggc ggttattgct
     7861 atgagtcttt tctcaccggt attgggaacc ttcctcatct tgcgtcgtca gagtttgatg
     7921 agtgataccc ttagccacgt ctcactttca ggtgtagcct ttggtctggt tttggggatt
     7981 tctccaactg tttctactat tgccattgtc ttgattgcgg cggtctttct ggagtatctc
     8041 cgtacggttt acaagagctt tatggaaatc gggacagcta tcctcatgtc aacaggtttg
     8101 gctgtttctc tgattgtcat gagcaagggt agaagctcga gttcaatgag tttggaccaa
     8161 tatctctttg gttcgatcgt gactatcagt gaagaacagg tcatttccct ctttgtcatt
     8221 gcggcggttg ttttgatttt gacctttctc tttcttcgtc ctatgtatat cttaactttt
     8281 gacgaagata cggcctttgt ggatggcttg ccagttcgta ccatgtccat tctttttaac
     8341 atggtgacag gggtggctat tgcccttatg attcctgcag caggagctct tctggtatcg
     8401 accattatgg tcttgccagc tagtattgcc ctgcgtctgg ggaaaaactt taaatcggtt
     8461 atgctgcttg ccagtgcgat tggctttttg ggaatggtag caggacttta catttcctac
     8521 tatgcagaaa cacctgcaag tgcaagtatt accattattt ttgtaactgt ctttatacta
     8581 atcagtttag taagacgttt tatcaaatag gagacgaacg tgaaaaaaat tagcttatta
     8641 ctagccagtc tatgtgcctt gtttttagtg gcttgttcca atcaaaaaca ggcagatggt
     8701 aaactcaata tcgtgacaac cttttaccct gtctatgaat ttaccaagca agtcgcagga
     8761 gatacggcta atgtagaact cctaatcggt gctgggacag aacctcatga atacgaacca
     8821 tctgccaagg cagttgccaa aatccaagat gcagatacct tcgtttatga aaatgaaaac
     8881 atggaaacat gggtacctaa attgctagat accttggata agaaaaaagt gaaaaccatc
     8941 aaggcgacag gcgatatgtt gctcttgcca ggtggcgagg aagaagaggg agaccatgac
     9001 catggagaag aaggtcatca ccatgagttt gacccccatg tttggttatc accagttcgt
     9061 gccattaaac tagtagagca catccgcgac agcttgtcag cagattatcc tgataaaaaa
     9121 gtgacctttg agaagaatgc agctgcctat atcgaaaaat tgcaagcctt ggataaggct
     9181 tacgcagaag gcttgtctca agcaaaacaa aagagctttg tgactcaaca cgcagccttt
     9241 aactatcttg ccttggacta tggactcaaa caagtcgcaa tctcaggact ttctccagat
     9301 gcagagccat cagctgctcg cttggcagaa ttgacagagt atgtcaagaa aaataaaatc
     9361 gcctatatct attttgaaga aaatgcctca caagcccttg ctaacacact ttcaaaagaa
     9421 gcaggtgtca aaactgatgt cctcaatcct ttagaaagtc tgacagaaga ggacaccaag
     9481 gctggagaaa actacatttc cgtgatggag aaaaacctca aggctttgaa acaaacaaca
     9541 gaccaagaag gcccagcaat cgaacctgaa aaggcagagg ataccaagac agtccaaaat
     9601 ggttacttcg aggatgcagc tgtcaaggac cgcaccttga gtgactatgc aggtaactgg
     9661 caatcagttt atcctttcct tgaagacggc acgtttgacc aagtctttga ctacaaggct
     9721 aagttgactg gtaagatgac ccaggctgag tacaaggctt actatacaaa aggctatcag
     9781 acagatgtga ctaagattaa cattactgat aatactatgg aatttgttca aggtggacaa
     9841 agcaagaaat acacttacaa gtatgtcggt aagaaaattt tgacttacaa gaaaggcaat
     9901 cgtggcgtgc gtttcctctt tgaagccaca gatgctgacg ctggacaatt caagtatgtt
     9961 cagtttagtg atcacaatgt tgccccagtt aaggcagaac atttccatat cttctttgga
    10021 ggcacaagcc aagaagccct ctttgaagaa atggacaact ggccaaccta ctacccagat
    10081 aacctatctg gccaagaaat cgcccaagaa atgttggcgc attgatgaga aatcgactag
    10141 ttcataagag ctagtcggtt ttttgatact agatggctaa cttcattata gacctttcag
    10201 aactttaaac aataaataaa actcttgaaa tatctgggct tatatgctag aatgtagtta
    10261 gtgtataagg ttcattagaa caccaaagcc cctaactagt gccatagtta agggcttttt
    10321 tgacgtatct tagcgattta acgggtgttt ataggctagt cagtcggtct acttcttacc
    10381 atctagccat ttgcagacga aatacaagat aattccagct ataacatctg ctataatagt
    10441 aagagcaagc tctggtataa ggctcattag tttcacctcc tctcacgaac ccataggaac
    10501 gtaatcggta accgatgaca aaaatagtat accacactaa atttagatca tcaacctcac
    10561 ttaatgcttg aactattgta gattatatgc taaaatgtag ttaattgata aggttcatta
    10621 gaacaccaaa gcccctaact atggccgtag ttaagggctt ttttgacgta tcttagcgat
    10681 ttaacgggtg tttataggct agtcactcgg tctactcctt actatctagc catctgcaga
    10741 cgaaatacaa gataattcca gctataacat ccgctataat agtaagagcg agctctatga
    10801 taaggctcat tagtttcacc tcctctcacg aacccatagg aacgtaatcg gtaaccgatg
    10861 acaaaaatag tataccacaa tatatttaga tcatcaaggt cacttaattc ttgaaatata
    10921 gggtctaggc gacaaagtct ttaaaatcag aaaaacgcat aatatcaggt gtgcaaaaac
    10981 ttgatactat gcgttttatt gtgggaaggt ttactccatt ttctcctgaa attgagtttt
    11041 tgtccagcct ctgtttttag aattgctaag aaaataatgt catgtggtga atatttgtaa
    11101 atcagtcagc agacagaacg aatactcttc gaaaatctct tcacatcatg tcagcttcgt
    11161 cttgccgtgt ccatggggga cttgacttga tcagttttca aatctgtact ttgagcaagc
    11221 tgagactagc ttcctatttg attttcattg aatatcagaa acccattctc catcaaataa
    11281 ttcgactgcg tctaataatt tttggtctgg caaggtgtca gaaataaagg ttgtgtattt
    11341 ggagagggga ttaattttaa aaaatccagt cttgtaaaat ttagaactat caatcagtaa
    11401 gatggtttca tgggctttgt caataatatt cttttttgaa atagcttggc tgagagaagc
    11461 ttcataaaca tattggtcat caatacctct tgctgaacaa aatgctaaat cgatattaaa
    11521 atgatctaat aaagaatttt ccttatcata gttgaccacg gaacaggatt gatgtttgac
    11581 ctcgccagat gtgataaaga ttttggagct atctttaaca gtttcagata gggtttgtgc
    11641 agtatgtaaa ccatttgtaa aaataatcaa attatcaagt tcagaaagat agggacaaag
    11701 ttcgtagaca gtagtactag aatctagata gatacacata ccagaccgaa taaagtcttt
    11761 agcgagacta gcgattagtc ttttttgcct agtactttct ccttcccgta tttgatgaga
    11821 aagttcaatt gtgttcatag aggacagggt cacgtatccg tgctttcttt tgataagacc
    11881 ttgattttct aagaaaatta aatcacgacg taaggtactt gtgctggaga aagtgatttc
    11941 tgccagctct tttacggcaa ttcttttttt ctttttaata atttcaatca attcaagtac
    12001 acgttcatct tttatcataa gctcctccta atttatcatt tcaactatat tatagcacaa
    12061 attggaggaa tttgaattat ttttatgaat attgggttaa catttgaaca ttattcaagt
    12121 aagcgttcac atattgaaaa aataaaacgt ggggattata ataaagttaa tcaaggacga
    12181 agagagaaga aaaatggaag cggttttagc aatagattta ggtgcgactt ctggaagagc
    12241 aatcgttggt tacctttctg aaaataaact agtaatggaa gaaataaatc gcttttctaa
    12301 tctacctatt agagtaaaag ggcatttatc ttgggatatt gactttctac tagctaaaat
    12361 tcttgaaagt atccgcttgg ctaatactag ttacaagatt ttatctatcg gtattgacac
    12421 atggggagtt gattttggac tgattgataa tgaaggtaag ctgttatcac aacctgttca
    12481 ttatcgtgat gaaagaacaa agggagtgtt aaaggaaata tctgaaatga ctgaattaga
    12541 aaaactgtat tcagagacag gaaatcagat tatggagata aataccttgt ttcaactctt
    12601 taaggcacgt caagaatctc ctgactcttt ctataagacc aataagattc ttttaatgcc
    12661 agatttgttt aattatctct tgacaggtaa gtttgctaca gaaaaaagca ttgcttcaac
    12721 aactcaatta tttgatccta ggagtcaaaa ttggaatcag aatatcttaa aactatttga
    12781 attggattca tctttacttc ctgaaattgt ttcagaggga aatgttcttg gaaggataaa
    12841 aaaggagtat ggtttaggcg atattcctgt tgtgaatgtt tgtagtcatg atacagcaag
    12901 tgcgattgtc tcagtaccta agacagaagg tagtttattt atttcatcag gtacttggtc
    12961 tttggttgga gtggaactta cttcaccgat tcttactacc gaatccttca gttatggatt
    13021 tacaaatgaa gtcggtaaag atggagtgat tacatttctg aagaattgta cagggttgtg
    13081 gatcatagag gaactaagac gttcatttga acgaagaggg aaagcctatt cttttgatga
    13141 tattaggaca atggtggaga aagaaaaaga aaatcttcct ctgattgata ctgaatcaac
    13201 tgaatttgca acagaatctg atatgcacaa gactttgaca gaatatctag cttatcatca
    13261 tgaaactaga gagtggacag atggacaact atttaagatt gtttatgaaa gcctagctga
    13321 aacgtatagg aaagcgatag agttattaga agaactaact cataaggttt ataagaggat
    13381 atatgtgatt ggaggaggtg ctagagccag ttattttaac caaatgattg ctgatagaac
    13441 tggtaaagag gttcttacag gtttgactga ggctacagct gtggggaata ttgttgtgca
    13501 gctcatagct atgggacaat taaaagggat ggaagaggct caccatgtta ttgaggagtt
    13561 tctacaatta gagagttatt actcccaaaa gaattaaaaa gattgagagt ttgtaaattt
    13621 gcctccctcc cccttcttag cttttgtgca ggaagggggg ataattggtg aattgaaaaa
    13681 tatttagtgt tttgatatga ggaggacaag gatgtcagat gtaaaacaag aattaattaa
    13741 atatggtaag aagctagtag aaacagattt gacgaaagga acaggtggga atctcagcgt
    13801 tttcgatcgt gaaaaacaat tgatggcaat taccccgtcg ggtattgatt tctttgaaat
    13861 caaagaatcc gatattgtag tgatggatat taatggaaat gttgtagagg gagaacgctt
    13921 gccatctagc gaatggtata tgcatttgat tcaatatcaa actcgtgatg atatcgatgc
    13981 aattatccat gctcatacaa cttatgcaac agtattagct tgtctcagag aaccacttcc
    14041 agcgagtcat tatatgattg cagtggcagg gaaagatgtt cgggtagctg agtatgcaac
    14101 atatggcacg aaagaattgg ctgtgaatgc agctaaagca atggaaggtc gtagagcagt
    14161 tttactagcg aatcatggaa ttttagcagg tgcacaaaat ttattgaatg catttaatat
    14221 tgttgaagaa gttgaatatt gtgcaaaaat ttattgttta gctaagaatt ttggagagcc
    14281 agtagttctt cctgatgagg agatggaatt gatggcagaa aaatttaaaa catacggtca
    14341 gagaaaatag ggaggatatt aatgttaaaa catataccga aaaatatttc tccagattta
    14401 ttgaagactt taatggaaat gggacatgga gatgaaatag tattagctga cgcgaattat
    14461 ccttctgcct catgtgcaaa taagctaatt cgttgtgatg gcgtaaatat tccagaatta
    14521 ttagattcca ttctgtattt aatgccatta gatagttacg tcgatagttc aattcagttt
    14581 atgaacgttg tttcgggtga tgatattcct aagatatggg gtacctatag acagatgatt
    14641 gaaggtcatg gtacagatct taaaacgatt acttatctta gaagagaaga cttttatgaa
    14701 cgtagtaaga aagcttatgc tattgttgct acaggagaaa cttcacttta tgctaatatt
    14761 atccttaaga aaggagtagt tgttgaaaga gaaaatgttt aatagaggaa ttttagttgc
    14821 cagtcatggt gattttgcta gcggagctct catgaccgca gaaatgtttg ttggtgagac
    14881 aacaaatgat agagttagga cattaggttt gatgcctgga gagaatattg tagagtttga
    14941 gcattatttt aaaaatcaag tggatgaact gttagactca aatcaagagg ttatcgtttt
    15001 gactgacttg attggaggaa gtcctaataa tgtggctttg tcacggtttt taaatttgga
    15061 ttcagttgat attgtaacag ggtttaatat tcctctccta gtggaattaa tatcaaatta
    15121 tgattcaaaa atcaatttag aagaaattgt tcacaatgct caaaatagtt tgtttaatgt
    15181 taaacaacaa cttaacgtag aggaggaaga aaatttatgt ctatagagtt tgttcgtatt
    15241 gatgaccgtc tggtacatgg tcaagttgtc actacgtggc taaaaaagta tgatattgag
    15301 caagttatca ttgttaatga tcgcatctca gaagataaaa cacgacaatc tattttaaag
    15361 atttctgcac cagtaggttt aaaaattgtt ttctttagtg taaaacggtt tgtggaagtt
    15421 ttaaactctg tgccaataaa aaagagaaca atgctgatat atacaaatcc aaaagatgtg
    15481 tatgattcta ttgaaggaaa tttaaaattg gagtacctca atgtaggaca gatgagtaaa
    15541 acggaggaaa atgaaaaggt aacgggaggt gtagctctag gtgaagaaga caaatattat
    15601 tttaagaaaa tagttgataa gggaacgaga gttgaaattc aaatggttcc taatgataaa
    15661 gttacaatgt tggaaaaatt tttataaaaa taatttaagg aggtacagta tatgctattc
    15721 acacaagcat tactggtgac attagttggg attattgcca ctattgacta taatggaccg
    15781 ttatttatga ttcaccgtcc gttagttaca agtgcaatgg ttggcttagt cttaggagat
    15841 ttcacccaag gtgttcttat tggttcagct cttgaattaa cttggctcgg tgtaacaggt
    15901 attggaggtt acactccacc agatactatt tcaggtgcga ttattggtac tgcatttggt
    15961 attttatctg gtcaaggaga aactgctggt atcgctatag cagttccaat tgcagttgct
    16021 acccaacagt tggatgttct tgcaaaaact ttagatgttt attttgtgaa aaaagctgat
    16081 aatgatgcta aaaacggaga ttattcaaag atcggttttt atcattattc aagtttggtt
    16141 ttaatcacgt tatttaaaat tgtaccaatt ttcctagcta ttatgcttgg aggggaatat
    16201 gtggcagact tgtttgctaa ggttccacca atcgttatgc agggacttaa ctctgcaggt
    16261 gctttactac cttcaattgg ttttggtatg cttttaaata tgatgctcaa gaaaaatatg
    16321 tgggtattct tgttgattgg attcatttgt tctgtgtatg gaggaatgtc aaccattggg
    16381 atctcactag ttggtattgc ggtagcatac ttctacgata tgattggaag taaaccacaa
    16441 gaaacaactt caagtagtga tgttgaggag gatcttgatc tatgatgaat aataaagtaa
    16501 ctaaagttga acttaaaaaa gttttcaaac gaagttttat gtatggttct tcatggaact
    16561 atgagagaat gcagaaccta ggttttctat atacaattct tccagtattg aaaaaactat
    16621 acccagacaa agattcagct tctcctgcaa tgaaacgtca ccttgagttt ttcaatactc
    16681 atcaaacagc ggcaccattt attcttggag ttacttccgc tatggaagaa caagaaggaa
    16741 atgaaggtgc agcttcaatt actggtatta aagttggctt gatggggcca ctggctggtc
    16801 taggagatag tttgttctgg ctgacactag ttcctatctg ttttagtatt ggtgcgtctt
    16861 attctaaaga cggcggtgct ttaggtatct ttatcgcctt aatattgttt aatattatta
    16921 atattcctgt taaatatttc ggtttgaaat atgggtatac taagggttct agtcttatcc
    16981 aagaaaataa tacaaaagga acattgaatc gcgttacgag tatggcgaca gcattagggc
    17041 tagtactagt gggtggtttg attccatcaa tggttggtat taattttgga ttagaattta
    17101 agcaggggga acttgttatt tctgttcaag aaatgattac aaaattaatt ccaggattta
    17161 tccctatggc tttgacttta ttaatgtgta aattaattag aaaaggaaag aatccggttg
    17221 tactaatctt tagtgttatg gctattggag ttatcctagt tgttttagga attttgaagt
    17281 agtagaaagt gtggaggtgg tatttgggat atcacctcca ttttggaaga gaggtaaaga
    17341 gtgaaattat ggtataagaa agctgcctca aattggaatg aagccttgcc gattgggaac
    17401 ggtcatttag gtggtatgat ttatggttca gctacaaaag aatgtattca actaaacgat
    17461 gagactattt ggtatagagg aaagtcagat agaaataatc cagactcact attgcatctt
    17521 aaaaaaattc gggaatatct tttagatgga gaaattcaga aagccgaaga attgataaag
    17581 ttaacaatgt ttgctacccc aagagatcaa agccactatg aattacttgg ggaactttac
    17641 attgagcata tagatattca gtcttgtgct ctttcattgt atgaaagaga gctagattta
    17701 gatacagcta tttctaatgt tgtgtttgag cctaatagtt gtaatttaca aataaaaaga
    17761 gaatatttta cgagttttaa taagaatatt ttatgttgcc gtatagtgtc atcagttcaa
    17821 aacacattaa atttaaacat taatttgggt agaaataaac ggtttaatga cgaagtatct
    17881 aaactggatt caagtacaat tttaatgtcg gcctctgctg gaggtagaaa aggtgttcag
    17941 tttaaagtag tatgtcattc taaagttacg gatggtgaag taagtgtatt gggagagaca
    18001 atagttattc ggaatgctac agaggtattt ctttatctca aatcaatgac ggattattgg
    18061 ggaaatatag atatttcttc tcttcaggga gaatttagta gtattgatta ctttacagaa
    18121 aaagatgaac atgtaaaaaa atatcaggag caatttaata gagttgattt taaactagac
    18181 tatagtaaag attgtcttag cattccaacg aatctacttc ttgaaaacac taaaaagtat
    18241 agtaactact tgactaactt gttatttcat tatggaagat atctgttaat atcgtctagt
    18301 caaccgaatg gtttacctgt caatcttcaa ggaatatggt gtgatgaatt aaatccaatt
    18361 tggggttcta aatatacgat taatattaat actcaaatga attattggat ggtaggtcca
    18421 tgtgatttac cagaagtaga atatccatta tttgatatgc tcgaaagaat gagagaaccg
    18481 ggaagactaa ccgctaagaa aatgtatgga gctagaggtt ttacagcaca tcataatacg
    18541 gatggttttg gcgatacggc tccccaatct catgccatgg gggctgcaat ttgggtatta
    18601 actattccat ggttatgtac tcatatttgg gaacactatt tatatttcca agatgagcgt
    18661 attcttacgg aacattttga aatgataaaa gaagcatttc ttttctttga agattattta
    18721 tttgaggtgg atggctactt gatgacaggt ccaagtgtct caccggaaaa taaatatcgc
    18781 ttaaaaaatg gtattgaagg aaatgcttgt ctatcatcta caattgataa tcaaattcta
    18841 agatattttt gtgattcatg cattggcatt gcaaaacaat taggagacaa ttcggatttt
    18901 attagtcgtg tgaaggagtt aaaaaagaaa ctacctaaaa caaaaatagg tagtaatggg
    18961 caaatccaag aatggttaga agattatgaa gaagtagagc ctgggcatag acacatttca
    19021 cctctatttg ggctttatcc ttataatgag attgatattc ataaaactcc ggaattagca
    19081 gaagcagcta aaatcactat caataggaga ttatcaaacg ctaacttttt atcttcacag
    19141 gagagggagc aagcgattaa taattggtta gtaagtggtt tgcatgctag tacacaaaca
    19201 ggttggagtg ctgcatggct gattcatttt tttgcgagac tatatcaagg tgaacctgct
    19261 tataaccaga ttaatggttt gttaaataat gcgactcttg gcaatttatt tcttgatcat
    19321 ccaccatttc aaattgatgg taatttaggt ttggtgagtg gaatttgtga attattagta
    19381 cagagccatc ataattggtt atcactaatt ccagctttac cttctgcttg gtcagaagga
    19441 gaagtgaaag gtttcagagt aagaggagga tataaggtat cgtttgcttg gaaaaatggg
    19501 gatataacat tcctaaaatt ggaaggagga aacaaagatc aaaaagtaag agtaagaata
    19561 tatggcaaaa atactgatgt acaaaatatt gaattggtat ttaattcaga aaaaattatt
    19621 gagttaaatt tttaggtata agtcatgaat aaagaaaaaa taaaaagaaa attaatcaca
    19681 atactgtttg tatgtattgg gatgttatgt tttggattgt tagcaggagt taaggctgat
    19741 aatcgtgttc aaatgagaac gacgattaat aatgaatcgc cattgttgct ttctccgttg
    19801 tatggcaatg ataatggtaa cggattatgg tgggggaaca cattgaaggg agcatgggaa
    19861 gctattcctg aagatgtaaa accatatgca gcgattgaac ttcatcctgc aaaagtctgt
    19921 aaaccaacaa gttgtattcc acgagatacg aaagaattga gagaatggta tgtcaagatg
    19981 ttggaggaag ctcaaagtct aaacattcca gttttcttgg ttattatgtc ggctggagag
    20041 cgtaatacag ttcctccaga gtggttagat gaacaattcc aaaagtatag tgtgttaaaa
    20101 ggtgttttaa atattgagaa ttattggatt tacaataacc agttagctcc gcatagtgct
    20161 aaatatttgg aagtttgtgc caaatatgga gcgcatttta tctggcatga tcatgaaaaa
    20221 tggttctggg aaactattat gaatgatccg acattctttg aagcgagtca aaaatatcat
    20281 aaaaatttgg tgttggcaac taaaaatacg ccaataagag atgatgcggg tacagattct
    20341 atcgttagtg gattttggtt gagtggctta tgtgataact ggggctcatc aacagataca
    20401 tggaaatggt gggaaaaaca ttatacaaac acatttgaaa ctggaagagc tagggatatg
    20461 agatcctatg catcggaacc agaatcaatg attgctatgg aaatgatgaa tgtatatact
    20521 gggggaggca cagtttataa ttttgaatgt gccgcgtata catttatgac aaatgatgta
    20581 ccaactccag catttactaa aggtattatt cctttcttta gacatgctat acaaaatcca
    20641 gctccaagta aggaagaagt tgtaaataga acaaaagctg tattttggaa tggagaaggt
    20701 aggattagtt cattaaacgg attttatcaa ggactttatt cgaatgatga aacaatgcct
    20761 ttatataata atgggagata tcatattctt cctgtaatac atgagaaaat tgataaggaa
    20821 aagatttcat ctatattccc taatgcaaaa attttgacta aaaatagtga ggaattgtct
    20881 agtaaagtca actatttaaa ctcgctttat ccaaaacttt atgaaggaga tgggtatgct
    20941 cagcgtgtag gtaattcctg gtatatttat aatagtaatg ctaatatcaa taaaaatcag
    21001 caagtaatgt tgcctatgta tactaataat acaaagtcgt tatcgttaga tttgacgcca
    21061 catacttacg ctgttgttaa agaaaatcca aataatttac at
//
LOCUS       DAVBEM010000039        20838 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVBEM010000039 DAVBEM010000000
VERSION     DAVBEM010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20838
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.039"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            182..658
                     /locus_tag="VQ548_001482"
     CDS             182..658
                     /locus_tag="VQ548_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2654317.1"
                     /translation="MKLSLYSEVEHYHFLSSYSLNDITYTDTPKNIIEKSKKDKYRYP
                     IVILNKDHKVIGFFCLHLNTGPKEYGYYQNDYALIRGFSIHDNFRNQGYGSNALNEIF
                     EFIDSTLKLEINHIILAVNEKNILAQKAYRNSGFSVVKKDLEGKRGKLIIMEKSRN"
     gene            complement(1332..1724)
                     /locus_tag="VQ548_001483"
     CDS             complement(1332..1724)
                     /locus_tag="VQ548_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET2654318.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLTRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTDKSQYEFLFPSVK
                     IKEEKTDKKEEVATDSSEKAEKKIRREA"
     gene            complement(1702..2163)
                     /locus_tag="VQ548_001484"
     CDS             complement(1702..2163)
                     /locus_tag="VQ548_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET2654319.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVGQLEAELDRSQFEKVEGNRLYMKQDDKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            complement(2126..2386)
                     /locus_tag="VQ548_001485"
     CDS             complement(2126..2386)
                     /locus_tag="VQ548_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654320.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            complement(2391..2819)
                     /locus_tag="VQ548_001486"
     CDS             complement(2391..2819)
                     /locus_tag="VQ548_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HET2654321.1"
                     /translation="MEGQIVKSMIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVE
                     EQIFFMEFEELYRETQKRSVASQQKTSLNLDGQMISNGSQKLTVPKGIQAPSGQSITF
                     DRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            complement(2788..3114)
                     /locus_tag="VQ548_001487"
     CDS             complement(2788..3114)
                     /locus_tag="VQ548_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HET2654322.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQGDGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            complement(3116..4132)
                     /locus_tag="VQ548_001488"
     CDS             complement(3116..4132)
                     /locus_tag="VQ548_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HET2654323.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLDFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            complement(4080..5021)
                     /locus_tag="VQ548_001489"
     CDS             complement(4080..5021)
                     /locus_tag="VQ548_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HET2654324.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            complement(5097..5462)
                     /locus_tag="VQ548_001490"
     CDS             complement(5097..5462)
                     /locus_tag="VQ548_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HET2654325.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            complement(5613..6671)
                     /locus_tag="VQ548_001491"
     CDS             complement(5613..6671)
                     /locus_tag="VQ548_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HET2654326.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPKKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            complement(6834..7985)
                     /gene="nagA"
                     /locus_tag="VQ548_001492"
     CDS             complement(6834..7985)
                     /gene="nagA"
                     /locus_tag="VQ548_001492"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HET2654327.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            complement(8138..9955)
                     /locus_tag="VQ548_001493"
     CDS             complement(8138..9955)
                     /locus_tag="VQ548_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HET2654328.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMIFLLSATAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            complement(10056..11198)
                     /gene="tgt"
                     /locus_tag="VQ548_001494"
     CDS             complement(10056..11198)
                     /gene="tgt"
                     /locus_tag="VQ548_001494"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HET2654329.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMLLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAECGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            11328..12185
                     /locus_tag="VQ548_001495"
     CDS             11328..12185
                     /locus_tag="VQ548_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HET2654330.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            complement(12213..12857)
                     /gene="pcp"
                     /locus_tag="VQ548_001496"
     CDS             complement(12213..12857)
                     /gene="pcp"
                     /locus_tag="VQ548_001496"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET2654331.1"
                     /translation="MKVLVTGFEPFGGEKGNPTLEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSVTPERVAINQDDARISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVK
                     AGFMHIPYMMEQVVNRPTTPTMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(12964..13332)
                     /locus_tag="VQ548_001497"
     CDS             complement(12964..13332)
                     /locus_tag="VQ548_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HET2654332.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATRSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLWYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            complement(13343..13768)
                     /locus_tag="VQ548_001498"
     CDS             complement(13343..13768)
                     /locus_tag="VQ548_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET2654333.1"
                     /translation="MIEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIKVKEEMESILTEFERTELSRLLNKLVLGIENIEI"
     gene            complement(14193..15335)
                     /locus_tag="VQ548_001499"
     CDS             complement(14193..15335)
                     /locus_tag="VQ548_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET2654334.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETSSAVAEEAPQGTTPAEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            complement(15501..16121)
                     /locus_tag="VQ548_001500"
     CDS             complement(15501..16121)
                     /locus_tag="VQ548_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2654335.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNTFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            complement(16125..17405)
                     /locus_tag="VQ548_001501"
     CDS             complement(16125..17405)
                     /locus_tag="VQ548_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET2654336.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKLTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            complement(17466..18950)
                     /locus_tag="VQ548_001502"
     CDS             complement(17466..18950)
                     /locus_tag="VQ548_001502"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HET2654337.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVYESDS
                     YIEDPHTAVASAVYRKYQAVTGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            complement(19026..20303)
                     /locus_tag="VQ548_001503"
     CDS             complement(19026..20303)
                     /locus_tag="VQ548_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HET2654338.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            complement(20410..20493)
                     /locus_tag="VQ548_001504"
     tRNA            complement(20410..20493)
                     /locus_tag="VQ548_001504"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20457..20459),aa:Leu,seq:caa)
     gene            complement(20503..20574)
                     /locus_tag="VQ548_001505"
     tRNA            complement(20503..20574)
                     /locus_tag="VQ548_001505"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20540..20542),aa:Gln,seq:ttg)
     gene            complement(20588..20660)
                     /locus_tag="VQ548_001506"
     tRNA            complement(20588..20660)
                     /locus_tag="VQ548_001506"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20625..20627),aa:His,seq:gtg)
     gene            complement(20675..20745)
                     /locus_tag="VQ548_001507"
     tRNA            complement(20675..20745)
                     /locus_tag="VQ548_001507"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20711..20713),aa:Trp,seq:cca)
     gene            complement(20750..20830)
                     /locus_tag="VQ548_001508"
     tRNA            complement(20750..20830)
                     /locus_tag="VQ548_001508"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20794..20796),aa:Tyr,seq:gta)
BASE COUNT         6236 a         4735 c         3669 g         6198 t
ORIGIN      
        1 tggtattatc aatcatgaac taggattcta gttttgcagg aagtctaata atgaaaataa
       61 aggactaaag caataactct aaatacatct gatttttata ggatatttca taaaaaaaat
      121 ctacatacct agagtcctat ttagttatgt atcttacata aagagaaagg aattaattat
      181 catgaaatta tctttgtata gtgaagttga acattaccat tttttaagtt cttattcttt
      241 aaatgatatt acatatactg ataccccaaa aaatattatt gaaaagtcta aaaaagataa
      301 gtatagatac ccaatagtaa tacttaataa agaccataaa gtaattggat ttttttgcct
      361 acacctaaac actggtccta aagagtatgg ctattatcaa aatgattatg cgcttattag
      421 aggattttct attcatgata atttcagaaa tcaaggatat ggttctaatg ctctgaatga
      481 aatatttgaa ttcatagact caactttaaa attagaaatt aaccatatta tattggctgt
      541 aaatgaaaaa aatatattgg ctcaaaaagc atatagaaat tccggttttt ctgttgtgaa
      601 aaaagattta gaaggaaaaa gggggaaatt aattattatg gagaaaagca gaaactagta
      661 atgatactag tttctgcttt tctctaagtc tgctataaat ttataacatg ttgaaataag
      721 atgtgaataa attgattgca gaattcaaac caatttctaa caatgtttta gaaaactcgg
      781 cggactattc cagattcaat ccactatatt ctatcttatt tgcatatttt gagagaaata
      841 atctatatac taaactttta tgtttataat tcattccttt cgtttcactc aaggcacaag
      901 acagaatgaa aaagtggtgt gctctttatt ttgttttata ataatagtga gaaaacctat
      961 cactactaca aatcacgggg aggtgaataa gtgagtggta tagccactac ctcgcatttt
     1021 tataggtgtc attctttcca tcaagcacaa gaactgtgac taggagcacg taaacttata
     1081 attgaataag cgactcgttt gtgaaaggaa agaatagtca agggataggc agactcaaat
     1141 ttggtgaagg gaaacccctc atgttaaaag ccaaacttca attttaaaaa ttttaaaatt
     1201 tgtttcgtat tcactactcc ttgcctttat attggattga ttaagagaac ctttcgcgtt
     1261 tctagaaact acagtggact attctggatt caacgcatta tagttgaatt gactaggaat
     1321 tctctttctt ttcaggcttc tcttctgatt tttttctccg ctttttcgct tgaatcagtc
     1381 gctacctctt cctttttatc cgttttctct tctttgattt tgactgaagg aaacagaaac
     1441 tcatattgac tcttatccgt acgaacagtc gtcaccaagc ttgttttctt gttttgatag
     1501 ctcacctgac ctagattaaa aacctgttcc ccactttctt gctcggcttt atccttggtt
     1561 cgtttagcca tggcaaaagc aaccaatttt tctttattta aagcatagtc ttgatagtgg
     1621 gcgatttgtc gggtcaaata aaattgcaac aaaagactaa agatggctgc tatggtgact
     1681 gcgtagagga gaacacctgc cttaactttc ttctttttcc acacgataga tgaactccct
     1741 ttctaagcct ttttgaaact ggaaacgaaa atgaaccagt tgattgtcct ctgtaatctg
     1801 agctgatttg aggccataaa ccataggctg atacccccgt ccactagcat cggttttacg
     1861 aaaatcgtct gactttgact taccgatggc gatgtccttg tcatcttgct tcatgtatag
     1921 gcgattgcct tctacttttt cgaactgcga acggtctaat tctgcctcaa gttggcccac
     1981 aaacaagagc cactcctttt gctcgctttg ttgctggtag cgaacttctg aaatgaggag
     2041 ctgactcata gcttgaaaaa ggagtaatcc cccactgatg acaatgaggg caagcaggga
     2101 ttctaacaag gtaaaagcct tgaccttatg gctctttgat tgccaacaac tgttctgaac
     2161 catggtagac ctccaatccc ttttcactag aaaatacctg aatctcaact ccgttgatgc
     2221 ttacctgatt ttgccccgtc tgcaaggcca tcttagctac cctcaagact tcttcctttt
     2281 gcaagatttt tgcttcctct tgcctatttt tttgaatttg tcccaaaagg agggtcgcaa
     2341 tgctggcaaa gatagctaga gcgactactg cttccagtaa aatcactgcc ctaatttttt
     2401 gtttccttaa tgcgtttaat ttttccattt cctagatata attgatagcg aatcgctcct
     2461 ttactggtct gaaattcaac cttagccagg gacgaattgc ccccagctcg gtcaaatgta
     2521 atactttggc ctgatggtgc ctgaattcct ttaggaactg tcaacttttg actgccattg
     2581 ctaatcatct gcccatccaa gttcagacta gtcttttgtt gactagctac actgcgtttt
     2641 tgggtttccc gatagagttc ttcaaactcc ataaagaaaa tctgttcctc taccgctgca
     2701 aaagtggact ggacagagcc ggacaagccc aaggcaagga tactcacaag tcccaaaacc
     2761 aagagacttt ccagcatggt aaaggcctta atcattgact ttacgatttg cccctccatt
     2821 tttagtatag tattcattat aagctttaac ctgttcttcc gtgatgcgcc catctccttg
     2881 taacttgctc agagtagcat cttcattttt atccaagcta taaagttctg cctggctttc
     2941 caccacctta acaacagctg cttttccttt gtcattgact gcttcttttt gcttggtcag
     3001 attaggtaca aagagcaaga aaagcacgct gataatcagc aagaccacca acatctccac
     3061 caatgtaaaa gctttaacct tagctttttt caagaatgtc atcatttttt tcattttaaa
     3121 aatttacctc catattttga tacatgggca tgagcattgc cgcataaagt aaaacgataa
     3181 tcagtgccac aaagataaaa accagtggct gcaccaaatt catggtgcgg ttgactcggg
     3241 taaaaaaggc ttcccaagtt ttttcagcat agatttccaa ctcactaccc agcttggact
     3301 taacttcccc atactctatg atgagactca attccttcct aaagaaagga taggttccta
     3361 tcgtctgaga aaattcacgg ccatttttca gggtttgagc cagatcttga ccgatttctt
     3421 taaagagctg ggaaccttgt tcctgcatca tttgaaaaat ctgcgtcagc tccattccct
     3481 gtgaaatcat attcccccat tcacgtgcat aataggctgt caagtaggtc tgcacaaaga
     3541 ttccaataaa gggaaggcgt gctaagatag aaaagacact catcttagaa cttcttttat
     3601 aaaaagttag tgctaaaagg gcaagcacgg aaacaagccc taccatgcct agaaaaattt
     3661 gtggcagatt accgataatt cgggtggcaa tattgctact atccagttgt gggagcaggt
     3721 aattccgtag ccccagcata attaagagaa gaaaatccag caaaatcaaa ggataggtcg
     3781 ctacttcaat taactttttc ttgaccttgg ccagattgtc tagatattct tctatctttc
     3841 ccaaactcag gtgaagattg ccatgaactt cagctagaga taactgagtg acaatggtac
     3901 ttgaacatcc caaactttcc atcatttctg agaatgattt cccctgagac aagcctgtac
     3961 gcatctgggt cacacactgc ttgtccaaca aggaactcct atctaaaaag gagatagtct
     4021 ccaccagatg aaaaccgcta gaaaagagat tgttaaatag ggtgatgata tttttttgct
     4081 tagctgtagc taattttttc cgtctcagcc tgaagacttg tgatatgtcc atctttaaga
     4141 agttggtcaa tttgctcatt ccacttggct gcttggtgtt cttgataatc tctgtttgca
     4201 aagtcaacga ttcctcctcc cccgattaat ctctggtagc agactccttg cagaacaact
     4261 gccaattctt cttcactcac acccaactcc agcagacgct cataaacacc tcggatactc
     4321 ttggcgtgaa tggttgaaaa gactgtcgca cctgtcaaac tagctctgac cactgcacgc
     4381 gccgtctcgc tgtcacgaat ttctccgata atcaagagat ctggtcgatg acgcaaggaa
     4441 agtttgatta gattttcata ggttaggccg attgcttcgt tcaactgcaa ctgaagcatg
     4501 tcgtcctgct tgatttcgac aggatcttcg atggacataa cttgctgtcc tttaaagagt
     4561 gacttggaca attcatgcat caaggtcgtc ttaccactcc caaccgggcc agcaaaaaga
     4621 tagagtcccc gttgcctgta ctgcttgcct aattcttcaa tatcctgaaa ccaaaaatgc
     4681 aagtcctgct cctcatcgtg caacaaacgg ataaccaaac tctcatgccc ccgataatcg
     4741 cctacagtag ataaacgtag agacgccatc ttctggtcat aggcataatc acaggaaccc
     4801 agttgactac gtcttttttc tcccacattc atacccgcca caaacttaaa gtgactgata
     4861 acggctgcaa acttttcaaa atcatagcta ccaattttac agcgctcgtc tcctaccctc
     4921 atatgaagct cataggcgtc taacttaggg acaaaataaa tatcctgcgt cccttttttc
     4981 cgagctgaac gaatgatttc ttgtgcaatt tcttgaacca tacttacctc ctcacctata
     5041 ctattcgcaa agcgttagaa aaataaaaaa agcaactcca aaaaagttac ttttctctat
     5101 tttaatttca tacggcaaga acgattcctt tcctgactgg tttgtttttc atagcctgag
     5161 cgtagttttt cgtctgggat aacctgctca tcctgcaaaa gagccaaaga atggtattgt
     5221 tgtaaatact catcacattc atcacaccag cgttggtctt ccgggtccca aaaaatggtc
     5281 atcaagtcgc ttctactttt ataaagaggg gattcttgtt ccaatctaaa ccagcaagtt
     5341 ttgtagtatt tgagagcatc ataatactgg tcaaattttc tacttgctac aatatcttct
     5401 tcccaacctt ctaagaacca ccacggttca aaatctccgt acatttctat aacacgatac
     5461 atattcattc attcctttgt accgtatatt ataaccaatt ccgccagaca aggaaagaaa
     5521 tatgctcatt tcttaatttt ttgataaaaa atccagccat ctgatggatg actgaatttc
     5581 tatttgctta tgtacaaaaa tatttttact acttaggctt ctgagatatc gttttcgata
     5641 atgaccttaa tggcatggtg gtctgctgcc ttactgaaga cttcgtaggc tttttcaatt
     5701 tcactgagtt tgaaatagtg agttaccaat ttttccggtt caatcttatg actttcaagt
     5761 gctttcaaca attgtggagt cgtatttgta gataccaaac cagttgttac attgatgttg
     5821 cgaatccaaa gtttatctaa atcgaattca actggtttac catgcacacc acagttggca
     5881 accgttccgt ctacaccgat aatcttttga cagaaatcaa atgtttcagg aatccctaca
     5941 gcttcgatag cgacatccac accacgacca tctgtcaaat cataaatttc tttaatggct
     6001 tttttagggt ctgaagaatt aaccttatga gtcgcaccga atgatagggc agtttccaag
     6061 cggttatcgt ctaggtctac cataatcaat ttagctggtg aatagaattg ggctgttaaa
     6121 agagcagcca atccaactgg acctgaacca ataatggcta cgctgcaacc aggttctact
     6181 ttccctttta agacaccaat ttcatatcca gtaggcagaa tgtctgacag cataaccaaa
     6241 gcttcatctg acaagtcttc tggagtatgg taaagagtat tatctgcatg agggacacgt
     6301 agatattcag cctgcatacc atcaatcaag tgaccgaaaa tccagccccc ttcgtcttca
     6361 cagtgggcat aaattccttt tttacagtag tagcatttac cacaggcaca gacgcaagaa
     6421 atcaagacct tgtcaccttt tttgaagttg gaaactcctt ccccaacttc ttcaacaatc
     6481 ccaatccctt cgtggccaag aatggtacca ctttggcaag taggaacatc ccctttgata
     6541 atatggaggt ctgttccaca aatagtggtt tttacaatac gcacaatagc gtctgttggc
     6601 ttgcgaataa ctggtttgtc tacatcaaca aaagaagcaa gtcctggttt aacataagta
     6661 taggctttca taaagcactc ctccgttttt ttatttgtaa tatttatagt tcaattgtaa
     6721 gcctttttct ttgtttcttc aagctttttt tgtgattttt ttaacttttt atttaccagt
     6781 aaagtaccct gtataaaaaa gcagaagcta gtctctaact tctgccttct ctcttatgct
     6841 tgataacgtt tcacaccatc taggtaggtt gctaccaatt ccaaatcttt atctaatacg
     6901 atgaagtcag cgtcgtagcc ttcacggatt tggccacaga cgtcatcgat gtgaacggat
     6961 ttagctgggt tgaagctggc catcatgact gcttcatgcg gattcgcaat tccccattcg
     7021 accacattct tcaaaccatc tttgagtttg aggatagaac ctgccaagtt acctgtcgat
     7081 ttgaggcgtg cagttccatt tgcaacgaca actgggaatt ctcccaacat ataatctccg
     7141 tcttccaatc ccccagctgt catacagtct gtgataagag cgatgttttc tgttcctttt
     7201 tgtttgataa gaatttcgca agcctttgga tctacgtggt gaccatcaca gatcaactct
     7261 gcataggtat gtggcaattg gtacatggct ccaaccatac ccaattcacg gtgagtcaac
     7321 ccacgcattc cattgtaggc atgcacccaa acactcgctc cagcatcgac tgcttttttg
     7381 gcttcatcaa aagtcgcgtt tgaatgtcca agagcaaccg tcacaccttc gcccgtaact
     7441 gtacgaacaa agtcttccac cccatcacgt tctggtgcaa gggcaatttt attaagcaag
     7501 ccatttgccg ctttttgcca agaatgaaac tcctcaacac ccgggtctct catataagtt
     7561 ggattttgtg cccccttaaa agtttctgtg aaatatggac cttcataata aatcccacga
     7621 atcttagcac ctgttgcttc tttataatgg tttccaagat tttcagtgac tgcaagcaat
     7681 tgctcataag tggctgttaa agttgtgggt aagaaactgg taacaccggt actaagaagt
     7741 ccttcactca tagtatgcaa tgtaccttca atgttgttgt ccatcacatc tacacctgca
     7801 tatccatgaa tatgagtatc cacaagtcct ggggcaatgc tataacctgt atagtcaatc
     7861 acctcagccc cttcaggaat ctgctctaca tgtttcccaa acttgccgtc cacaagttcc
     7921 aagtaaccac ctcgacgaac tccgtgtggg tagaaaaact gatccgcttt aatatagtta
     7981 ggcataatgt taacctcctt aaaagattga ttctacaatt tattatgtca attacattat
     8041 aaacctttct tttttatttg taaatggtat agacctattt tttggagata ttttaaaaga
     8101 gctggatttc tccaactctt ctctttttta atacaagtta ttttgattta accggcttgt
     8161 cttgagctgt ctgcaaagct gtggcaatcg tatctgcata caattttgct cctgcttcga
     8221 tagtgctact ctcactcccg aaatgaacct ggtctgttcc agcccaaatt tctggatgct
     8281 ctttcgcaac ttgattccaa tctgctatcg taatgtaagg tgtcttctct gccaattctc
     8341 tcatataggc agcagccttc tcaacgatgg cataggtctc ttttgtctta tctccctcat
     8401 aaggagtcac caaaatcata tggtgtccct taggaagatt tttcacgata ctgtcccagt
     8461 catccttgta attctcagga ttatttaccc cagtcgcaat gaccaccgtc ttaggtaaaa
     8521 atttattctg gctattattt agcatgattt catttgcggt cttggttgtt acgctgacct
     8581 gcgcgttaat ctgtgctcca ggaagagctg tctgtagtgc tgtatttgcc cttaaagcca
     8641 ctgagtcacc aattaacata gtgccatcag caattcccaa actgtttgca tctgcccgtt
     8701 ctgccatcac cttggtctgg ccaatatttg ttgcagcttg cttcaagcca ttgacagtca
     8761 agtctgtctc aaacgctccc acttgtggtg ccaacaaggt caccatgcag acaatgaagg
     8821 tcaagattcc tgtacctgct gcaagaattg cgtgaatata aggcagggga cgaagagttt
     8881 gtaaaatagg tgtgttcttg cctgcaatcc aaggttccaa tacataaaat gacagactgg
     8941 caaagccata agaacaaatc agagtcagta atacagcaag aagatttgat gtcaactgtg
     9001 agaaaatgat atagaaaggc caatggaaaa gataaaccgc atagctagta tccgctaaaa
     9061 agctgataat cttcggctcc tgtatatgat gtgtcttttc atgtaagaca cgcgccgcca
     9121 gaatcatggc aagagctgca agactggcaa gcaagaagcc gataagatag gcaaaaagat
     9181 aagtgaattt gacaaagaaa gtcaaaagaa ctaggaaacc aaagcctcct ccaaaaacta
     9241 ctaaagtctt tcgtaaatcc cagattttat ccaactgctt gacgagggaa gtcgtctgac
     9301 gaacgcctac aatagttgct aacatacttc ccaaaaagaa tggatagaca tgagttaaac
     9361 tggagaaata aacagaggaa taagaggtca ctagaaaact accaataaac atggagaaga
     9421 aactgatcaa gaaggcagta gcagataaga gaaagatcat ccccttcaac tgaccatttg
     9481 atttagcttg tttggataag aaccaaactg ccaatcccca aagaatatag tagtgaacct
     9541 caactgccaa actccaatta tgaacaaaca aatgaggaat gaactgagat tcataactcc
     9601 cacctgttaa gagttcatag aagttggtca taaagcctaa gacgcccgca atctggccac
     9661 caattccagc aacatagtct tggcgaacca agaaagtaaa aggcatggtc accaagacca
     9721 tcaaaaccac aggtggcaca atccgataaa agcgtcttct aaaaaatcct atcaaatcaa
     9781 tctcattgtt cttagaaaat tcttcaatga gtagagctgt aatcaggaaa cctgaaaatg
     9841 tgaaaaagac atctaccccg aaaaatcctc caggaaagat cgtctgaaag aagtgataca
     9901 agagtaccaa aagtaaacct ataatcctaa tcaaggaaaa ccatttaatg cgcatacgag
     9961 tttattcttc ctttcattgt acactttatt ctatcaaaaa aagaagaaaa atcctaagag
    10021 aaaacttagg atttttagct tatatcaatt ccattttaga aattacgtcc tgacttatta
    10081 tagccatatt tttccacaaa atacttacgg aattccaaga gattgtcatc catgatggct
    10141 tgtcgcactt gcttcatcag gttaagcaag aagtaaagat tgtggtagct agtcaagcgg
    10201 ataccaaagg tttcatcagc cttgagcagg tgacgaaggt aagcgcgtgt atagttatta
    10261 catgtgtagc aatcacactc aggatccagt ggcgtaaagt cctcagcaaa ctgggcattt
    10321 ttcacaacca aacgtccttg actggtcata caagtcccgt tacgagcaat tcgagtcggt
    10381 aagacacagt caaacatatc caccccacga atgaccccat cgatcaagct atctggcgct
    10441 cccacaccca tcagataacg aggtttattt tcaggcagca gttgagttgt aaagtccaag
    10501 accgcattca tctcttcatg ggtttctccc actgccaaac caccgataga gtagcctgag
    10561 aaatccatgc tgacaagatc gtgagctgat tggcggcgaa ggtcttcaaa tcctgcacct
    10621 tgcacaattc caaacaaacc ttggtcatgt ggacgacggt gagccttcaa accacactca
    10681 gcccaacggc tggtacgctc gatcgatttc ttaacgtagt cataaggttg ataaaactga
    10741 ggacattcat caaaggacat catgatgtct gaacccagat tattctgaat agagatggct
    10801 ttttctgggg ataggagcat cttagaacca tttagatgat ttttaaaggt tactccttct
    10861 tctgtgatat tacggctatc tgctaaagaa taaacctgaa aaccaccact atctgtcaag
    10921 ataggctggt cccaattcat gaacttgtgg agaccaccag cgcgtgcaat gagttcatct
    10981 ccagggcgaa gccagagatg ataggtgttt gataggataa ttcccgaacc catctccttc
    11041 aattcttcag gtgactgagt tttgacagtg gcttgtgtcc caactggcat aaacataggt
    11101 gtcggaaagg taccgtgggg agtgatgatt tctcctagac gagctcctgt gtgtttttct
    11161 ttcttaatca aacgatattt gattggtgaa tctgacattt tttacctccg aagctgggaa
    11221 agacagtccc agttcataca gtgtgcccaa ggacacactg tatgatttta tcaaaaaaag
    11281 taggaactgt cacgaactat gtataagaac tatggtataa taagagaatg aactatccaa
    11341 aaattgattt aaaaacaatt cgtcaggagt caaaacattt tcaggctgac accccccgtc
    11401 tctttctcct ctatatcctt cccagtatgc tggtcatctt atctggtttt cttaatccct
    11461 tatctcggat ccacgggact gttttagaac agccattttt cagcatactt ggccaaatac
    11521 ttcaaaccta cctctttcct ctactagtct cctttatcgg gactattctt ttgaccagtt
    11581 ccgtctatgc aacactgaca ctcatgaaag attctaaaac ggagccatct gtaaaaaaca
    11641 gcctagctct ctttgatgag gagcgctttt ctcaaacctt tttgacccta cttctcaaac
    11701 gtttctatct ctttttatgg agtatcccta atttacttgg gatttacctc ctcttttata
    11761 gtagcttttt agccaaaaaa ttcgtcaccc tacatcctga gtttccaaat ctagatctct
    11821 catcagttga aaccgagcgt ttcctcatgg tctttggact ctactttctt gcaagtctca
    11881 tcttgatcat tgtaggaaat atcctctata ttccacagta ttatgcctat tcacaggtgg
    11941 aatttcttct ctgttatagt ctagacctag gacaggtccc accaagacga atcctaaaaa
    12001 ctagccgttc ctttatgaag ggctacaagt tccagcactt tgtcctagat ttacagcttc
    12061 ttccttggta cttcctcaat tggattacct ttggcattgc tagtttttca ctcctacctt
    12121 atatccaatg cactaaaatt atgttttacc gagcagtatt ggctcgaaaa cgtccaaaag
    12181 cttgaaggtt tttcccctca agcttttttc tatcaatgag tttctccgcc taccaacttg
    12241 agttcctgat ctccatgttc tatcatagcg ccgattgctg cttctatccc tcgccgaata
    12301 tccactaaac tcatagttgg agtagtcggt ctgttcacca cctgttccat catataagga
    12361 atatgcataa aacctgcctt aacatatgga aatttctttt ctaccaaata gagagcctga
    12421 tacatcaaat ggctgcagac aaaagtccct gccgtattgg aaacagaggc cggtaagccc
    12481 tcttttttta tagcttgaac catcgcttta atcggcaaac tactaaagta ggccgaagca
    12541 ccatctgggc gaatgggacg gtcaatcggt tgattatctt cgttatcaga aatgcgtgca
    12601 tcgtcttgat taatggccac tcgttcaggt gtcacactag ttcttccacc agcttgccca
    12661 atacaaagga caaagtcagg ttgataacga ttcatctctt cttccaatac ttgagcagat
    12721 ttgtgaaaaa ctgtcggcac ctctagccaa cggacctcag caccatggat ttcagctggt
    12781 aaacctttaa tggcctccaa agttggattg cccttttccc ctccaaaggg ctcaaaacct
    12841 gtcactaata ctttcatttc taactcctca aaaccaattc aatgagactt ttttcttaaa
    12901 aacaagtata acatatttcc cttattctgg attaaaaagg attagcgaga ttaaaatcga
    12961 ccttcaagtg tatttaaaga gtaaaatact aatcaaggcc aaaatagctg atccaccttg
    13021 cttcaaaata atttttttat ccgctgttaa agagccgtaa gtcgcagcac caatcacaaa
    13081 taagacaaaa atagtcacaa tttctaaatt ctgtgagaaa taaatgccat accagagaaa
    13141 gactcctagc agagccttat aaatcccttg atttttgaac aatgaactta ctgacggatg
    13201 agccaattct tccttttcca tattaaatac acgactagtc gcatctgatc gcgtagcaat
    13261 actttccaaa taaaaaatgt aaaaatgctc caaagcaacg atcgttgtta aaataattgt
    13321 aataattgac atctatttct ccttaaattt ctatattttc aatacccaaa accaatttat
    13381 ttaataaacg gctgagttct gttctctcaa actctgttaa gatactttcc atctcttcct
    13441 taaccttgat atgttgcaga gggggattca ccactaactg ctccttggca tacttcgcag
    13501 cctctaccaa cacttcccgc tgattttcag gattacgatg acgctccacc aaaccttccg
    13561 tttccaaaat cttgaaatgc cgtgtcaaag cagcctgatc aattttcaaa cgctcctgaa
    13621 ccgccatttg gttacaagga gaatgctcca gcaaaaacag taaaatctga taccgtgtca
    13681 aactaatccc aagccttttt tcaaacaatt gcgtactcgc ttgctcagac aagcggagtt
    13741 gatacagtaa atcttgaatc tctatcattt cttcctccta tccattgact tatcaatagt
    13801 tgaccaatca attataatat aaagtatagt gaaatgaaat aagagcagga caaatcgatc
    13861 aggacagtca aatcgatttc taacaatgtt ttagaagcag ttgtgtacta ttctagtttc
    13921 aatctactat aaaatagatt gcaagaatgt tgcttagatt attacaagat gataactttc
    13981 cattttccat tcaaattgat actcaatgaa aatcaaaaag caaactagga agctagtcgc
    14041 aggttgctca aagcacagct ttgaggtttc agataaaact gacgtggttt gaagagattt
    14101 tcgaagagta tgacaaagaa aaaacgaacg agaatcgctt cccatcacga aagctagatc
    14161 tcattcgtca aaatgatgtt accaagtcgg gtttatccat tcattgaaac gtgaacgtga
    14221 tcatagtgat tttctgtcac actaccacgg tctggcattg ggttccaagt gttagctggc
    14281 ccatatttgc tatcgaatgg agcatagaaa cgttgtttcc agatgatgta actaatgcca
    14341 cggctggcca tgttttgaat agcatattcc gcaatcttat cccctaattc tgaacgttct
    14401 ggtaccataa agtcgatagc caaacctttt ccgtgatctc cactgtctcc tggacgataa
    14461 ccgctaaagg atgtaatgcc aaacaagtta gcaatttctt ctttaaaggc agctgtttgt
    14521 ggttgaagac ctgcattttc agattttgct actgcaagtc cagcataatc gggcgcagct
    14581 ggagcctcgt aagttgttga aattattttc gtctcttctg gttgataagt agaaactgct
    14641 gctgtagctc catttgatga tgctacttct tttgcttctg aacttgttgt agttgcttcc
    14701 actgctgatg cagcttgagg gcttgcttgt gtttcctgct tctcagctgg agtcgttccc
    14761 tgaggagctt cttctgcaac tgcactgctt gtttcggccg tttgctcctc tgggacagaa
    14821 gtgcccgtag atggtgccac ttcttcagaa gcaatcactg tctttgtaac ttctgaactt
    14881 gatgctactt cttttggagc ttctgcaatt ggttgagaaa ggtctgcaac ctgaacagtt
    14941 tgatcatcaa cggtcacttg attagtggtc aaatctgctg tcgcagttgt cacttcttca
    15001 ctagagtctg cttgaggtgt ttggatttca acttctgtta cttcttctgc ttcattgaca
    15061 gtcgttgtca aaacagtttc tgggaaaatc aagtccatat tagtgatttt gttcagattc
    15121 gcaagcactg tgacatctac acccaaggct tctgcaatgg tgctcaaagt atcaccatac
    15181 tgtacggtat aacttgtttt gttgtccgtt ttagtcaaat cgttttggat ttgctcaaca
    15241 ctacgtgcag tccaaagaac ttcttctgct tgagttgcca atactggggc aaatgacaag
    15301 gctactgttg acgctaataa cattcttttc ttcattcttt caaattcctt tcaaatgagt
    15361 acctgtctat cataacacaa aaaatgtaga aaaaaagccc tctcgggcct atttaacaga
    15421 actgtctatt ccttgtaaca aactagatta cttgaaatag tttgttaggt ctctgtcaca
    15481 aaactgacac aatcttttta tcacttagtc tcaaaaatac gggaaatatc tgctaacgct
    15541 tgaatcctgt gattcccttc ataagtagac tctaaaaagt tgatactttg aatcccacta
    15601 ttctgggcaa attccacatc cagagtccga tcccctatat aataagtatt atcagaattc
    15661 aactgatact tatctagcag ataggtagcc gcttctggac ttggcttccg cacaaagcca
    15721 ctctgactgg tcaaaatctc tgtaaaatag gattccaccc ccaagtcctt gagaatggta
    15781 aaagtgttgt tccccttatg agtatatata aactgctgaa ttcctgattc gtctgcccaa
    15841 gctagcacct cacgcgcacc tggcatcaaa actacctgag cattcttctc agccagactc
    15901 tgggcacgca cctgatttag cacctcaaca tccagatttc tatcttctgc cacccgcaca
    15961 agcaaatttt gcaccgaata cttgaagata aactctctca ccttctcctt atcataagga
    16021 atagaaaact gagcaaaagt ctcctcaatc cctgataaaa tcgcttcgta agagtccaat
    16081 aaagtcccgt ctaaatccca aataaaagct gttttttgca tttcctatcc tttcaagctc
    16141 atatagcgct ggtaacgata gcgtagaaat aaccagcgaa aaccattatc caagagagac
    16201 cctgcccaaa taccaggcaa gccccaacca agcacaatac ccatcagata tcctgtccca
    16261 atgcggatac accacatgcc tatacttgtc gcataaaaag ggaggcgtgc atttcctaat
    16321 ccctgccaga ctgccgtata gatgactgtt cctgtcgtca taggggtacc aagtagtgaa
    16381 aacagtgtca ctagaacact agcctccacc gctagagaat cagtcgtata gagatgagtt
    16441 aatggtacac ccaagacata tatactaaag gacaggggca acatgaggaa cagagaaagc
    16501 caaaaggttt gtttactcaa actagcaact cttttccaat catcctctcc aactgctcgg
    16561 gccaacagca tgaccgttgc cgtagcgaca ccaaaggcag gcatatagtt aaactgggtc
    16621 aagacttctc cgattgcatt cccagcaact gcctccgtcc caaaagaaac gaccaaggca
    16681 atgatcacta catctccagc cctcatcata agtcgctctc cagctgctgg taaagccaag
    16741 gtcaacagtt ccttatctaa accaaaagtt agcttcccat aaggcagttt taattgtgac
    16801 cacaaaatca caagaccaac caaacgagac agaattgtcc cccaagcaac accagctatc
    16861 cccatatcca gaacaaaaat agctagactt gaaaaaagaa tattcaaggc attggataaa
    16921 aaactaacat agagaggcag acgtggatta tgcgttgcac gaatcaaggc tcccaaacta
    16981 gtcattaaac ctaagagaac aatcgatccg cctaccaaag atagatacag tccaccactc
    17041 tcagctacat ccctctccgt ccccaaaagt cctatcatct ctttcccagc gaagatggac
    17101 aaaaatccta aaaggaaact taatagtaag gtaatcttca acgcctcagt cacatgatag
    17161 gccaacttcg actggtcttt ctgccctatg ctttttgaaa taacactgga aatagcagct
    17221 cccagagcga tgaaaatcgc ctgataaatg gtgataatat taccagctac tgaaacccct
    17281 gaaatagcta tcaatcctaa atgagcaacc aaataactgt ccaccattcc cattagcatc
    17341 tgcaaaaagt tttcacccat agctggcaat gcaatattaa gaatgtcttt atttttctta
    17401 aacaatctct cctcctgatg aaaagaaact cagttggttt cccaaccgag tttgctccct
    17461 ctgtcttaaa gtcctaaata agcctcaacc gctgcttgca tgtcagcagc tgccactgtt
    17521 gtcttgtgac gaattggagc tatttcaagc ccatcaactg ctggtggcac tgcaacgcct
    17581 gagatttcat gtaattgagc caaggcttca aagtctgtca aacctgcttt tccagttaca
    17641 gcttctactg caactactgg gaacttgtat ggactagctg ttgaagcaat cactgtctta
    17701 gttacatctc cagtaaccgc ttggtatttt ctataaactg ctgaggcaac cgccgtatgt
    17761 ggatcctcaa tataagaatc tgactcataa acacgcttga tttctgccgc tgtttcttcc
    17821 tcagtcgcat attcagctgc aaagaggtcc aaaatctctg catcaaagtc tgtcaactta
    17881 tattgtcctt gcgtgttcaa ggcattcata agttcagctg tcttttcagc attatttccc
    17941 aaaagatgga aaatcaagcg ctccaagttt gaagatacca agatatccat agatgggctg
    18001 gttgttacct taaactcacg ttttttgtca tagacacgtg ttttaaagaa gtctgtcaag
    18061 acattattgt catttgaagc acagattagc ttgccaactg gtaggccgat ttgtttggca
    18121 taaaaggcag ccaagatatt tccaaagttt cctgttggta ctgtgaagtt aaccttttca
    18181 ccagctacaa tttcaccagt cttaaccaat tgagcgtaag cataaacata ataaacaatt
    18241 tgtggcacca gacgaccaat gttcatagag ttagctgatg aaaattgcaa cttgttggta
    18301 gtcaattttt cacgaagagc cacgtcgtta aacatgtgct tcacatttgt ttgcgcatcg
    18361 tcaaaattac catcaatagc aataacatga gtattgtcac cattctgagt ggtcatttgc
    18421 aactcttgta ccttgctgac accacccttt ggataaaaga cgataatctc agtaccaggc
    18481 acatccgcaa accccgccat agcagctttc cccgtgtcac cagatgtcgc tgtcaagata
    18541 acaatcttgt tctccaaacc atgtttctta gcagcagtcg tcataaagta tggcaaaata
    18601 gacaaggcca tatccttaaa ggcaatcgtt gaaccatgga aaagttccaa attgtattgc
    18661 ccatctaatt tcactaatgg tgcaatagct ggagtatcaa atttgctatc gtaggcattg
    18721 ttgatacagt agtccaactc ctcagctgta aagtcatcta aaaatgctga caaaactagc
    18781 ttagcaactt cctggtaaga agcatctttc aatttgtcaa agtccaaatc tacctttgga
    18841 taagtaaccg gtgtaaacaa accgccgtcc gtcgccaaac cttgcaaaat tgcttggctg
    18901 gcagttactg tattgttggc atcacgcgtt gattgataaa ctaatgtcat tactctctat
    18961 cctttatcta tagtctcgtc cattatatca tgatttttca gaaaattctc cctttataag
    19021 agaaattata ggctcaattc ttctctcaaa ggctgtaaat aggtcatttc ttccttattt
    19081 ctcaccacta gtccctcctc agctagtagg agtaagtctt tggaaaattc aataatcgta
    19141 gtttcttcct catctgtaag atttttctta gaaaattgtc tccttaaaga cttgtaatca
    19201 taaccaaata ctttaaagaa aggtgctgtt tctaagtaag cttctaactt gtctaaatta
    19261 accaataatc ccaagtgaaa agctgcagaa gcaaaagtcc tatcaagtgg ctgtgtacac
    19321 acactacgaa actcaactgt tcctcgagtc gttaaatctt ggtactggta actacgatga
    19381 gtttcaaaat ccttctcttg ggggtaaata ataacctcat ccccattcag agcaaatgct
    19441 tggatttcgg acgtagccaa atagtcccca gcctgaatag gataaaaata ataggtctgc
    19501 ccatcacgtt ccgcagtaaa aatcgcagaa tgatttagat agtcaaaaaa atcagcttca
    19561 tcattaagga gtctagcatt gaccccaaca ttctctggat agataccatg catagattct
    19621 tcccagaaaa tatcccttga aattttcgta tcccaatccg cacccgaaaa ttcagagttt
    19681 gcaaataaat aagccttagc cgcttcaatt tgagtaaaag cattaatcac ccgtaagtag
    19741 ttggtttttg aaatatccag ctgaacctgg ctcccacaga taaaagtacc atattcaggg
    19801 aaatgatgta aatctgattt aataatattt ctactcaaat tcaaataatc catcaacatc
    19861 tgatagcgtg gataagccac tggacaattc tcatttttat cccagttggg atggatacca
    19921 cagccaacaa tagcatgatt tgattcagct aactttctct gaattacatt catataatta
    19981 ttgaaacgat tttcgacctc ttgaatcgtt tcagccttac caaatgcaaa ctcaatcgtt
    20041 gtataggaaa cttcaaataa aatagcatcc tgacttatcg gatctactaa ctggatcaga
    20101 ttgccaaaat catctacctt tgctacggtg agatccaaag tagaaactaa ataatgaaat
    20161 agatccttta taacttcaac atctgtagca tccccttcta aacttgcaac aggatactcc
    20221 aactcaattc cgacaaacaa ttcaggattt tctttaatat ttttcaaata ccgatgtttt
    20281 aataaatcga tagaacaaga catactaccc tacactttct taatctaaat aaaatttgaa
    20341 taactataat tataccaaaa ataatataaa aaaggaacga agaataacaa cgttcctaac
    20401 actatactat accggcggcc ggggtcgaac cggcacgtcc ttgcggacac tggattttga
    20461 gtccagcgcg tctgccaatt ccgccacgcc ggcaaatagt aactggggta gctggattcg
    20521 aaccaacgca tgagggagtc aaagtccctt gccttaccgc ttggctatac cccaataata
    20581 taaaataggc gagtgatggg gatcgaaccc acgcatgcca gagccacaat ctggtgtgtt
    20641 aaccacttca ccacacccgc cataattcta ttaacacggg cagtaggaat tgaacccaca
    20701 ctgaaggttt tggagacctt agttctacct ttaaactatg cccgtaaaat ggaaggggag
    20761 ggattcgaac ccccgaaccc gaaggagcgg atttacagtc cgccgcgttt agcctcttcg
    20821 ctacccttcc aaaatata
//
LOCUS       DAVBEM010000040        20674 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVBEM010000040 DAVBEM010000000
VERSION     DAVBEM010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20674
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.040"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(<1..189)
                     /locus_tag="VQ548_001509"
     CDS             complement(<1..189)
                     /locus_tag="VQ548_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2654339.1"
                     /translation="MLYVGIDIAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALENTGHYA"
     gene            444..1289
                     /locus_tag="VQ548_001510"
     CDS             444..1289
                     /locus_tag="VQ548_001510"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HET2654340.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(1436..2497)
                     /gene="dinB"
                     /locus_tag="VQ548_001511"
     CDS             complement(1436..2497)
                     /gene="dinB"
                     /locus_tag="VQ548_001511"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HET2654341.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            2845..5169
                     /gene="pflB"
                     /locus_tag="VQ548_001512"
     CDS             2845..5169
                     /gene="pflB"
                     /locus_tag="VQ548_001512"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HET2654342.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            complement(5536..5754)
                     /locus_tag="VQ548_001513"
     CDS             complement(5536..5754)
                     /locus_tag="VQ548_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654343.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(5850..6088)
                     /locus_tag="VQ548_001514"
                     /pseudo
     CDS             complement(5850..6088)
                     /locus_tag="VQ548_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6081..6365)
                     /locus_tag="VQ548_001515"
     CDS             complement(6081..6365)
                     /locus_tag="VQ548_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654344.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            complement(6977..7147)
                     /locus_tag="VQ548_001516"
     CDS             complement(6977..7147)
                     /locus_tag="VQ548_001516"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2654345.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEETG"
     gene            complement(7797..9020)
                     /locus_tag="VQ548_001517"
     CDS             complement(7797..9020)
                     /locus_tag="VQ548_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET2654346.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            9188..10510
                     /locus_tag="VQ548_001518"
     CDS             9188..10510
                     /locus_tag="VQ548_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2654347.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            10512..12398
                     /locus_tag="VQ548_001519"
     CDS             10512..12398
                     /locus_tag="VQ548_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HET2654348.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKELSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            12566..12910
                     /locus_tag="VQ548_001520"
     CDS             12566..12910
                     /locus_tag="VQ548_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2654349.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            12920..14332
                     /gene="lacG"
                     /locus_tag="VQ548_001521"
     CDS             12920..14332
                     /gene="lacG"
                     /locus_tag="VQ548_001521"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET2654350.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDITLAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGEIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            14402..16081
                     /locus_tag="VQ548_001522"
     CDS             14402..16081
                     /locus_tag="VQ548_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2654351.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMIAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QLISFVFLSLMLVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLDIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV"
     gene            complement(16207..17646)
                     /locus_tag="VQ548_001523"
     CDS             complement(16207..17646)
                     /locus_tag="VQ548_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET2654352.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(17650..18999)
                     /gene="trkA"
                     /locus_tag="VQ548_001524"
     CDS             complement(17650..18999)
                     /gene="trkA"
                     /locus_tag="VQ548_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HET2654353.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            19187..20035
                     /locus_tag="VQ548_001525"
     CDS             19187..20035
                     /locus_tag="VQ548_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HET2654354.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            20050..20598
                     /locus_tag="VQ548_001526"
     CDS             20050..20598
                     /locus_tag="VQ548_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HET2654355.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
BASE COUNT         6263 a         3513 c         4234 g         6664 t
ORIGIN      
        1 ggcataatgt ccggtatttt caagagcgat gagacagtct tggttgagct gtcgaagaga
       61 cagatctaag agttcaaaac cagctttatt atttgaaaaa gtgagtggtt taagaacagt
      121 ttttcctgga acattcaagg ctgtaacatc gtgtttattt ttagcgatat caatgcccac
      181 ataaagcatg ggagtacctc cagatatagt atttcaagtc tacttggtta tccacgaatt
      241 ttttgccttg ttaccttaga cgagatcaaa cgtctatgcg ttatcaaact cattaccaat
      301 tgaaacaaaa gctgtggtta gagcctttcg gaaatcgtca agcgattgga ggaaatgaac
      361 taatccacag tggcttattc caagtatacc acttgggctt tggcagtagc taactgcgct
      421 aattataata tagggagtaa tctatgtatc ttattgaaat tttaaaatct atcttcttcg
      481 ggattgttga aggaattacg gaatggttgc cgatttccag tacaggtcac ttgattttag
      541 cagaggaatt catccaatac caaaatcaaa atgaagcctt tatgtccatg tttaatgtcg
      601 tgattcagct tggtgctatt ttagcagtta tggtgattta ttttaacaag ctcaatcctt
      661 ttaaaccgac taaggacaaa caggaagttc gtaagacttg gagactatgg ttgaaggtct
      721 tgattgctac tttaccttta cttggtgtct ttaaatttga tgattggttt gatacccact
      781 tccataacat ggtttcagtt gctctcatgt tgattatcta cggggttgcc ttcatctatt
      841 tggaaaagcg caataaagcg cgtgctatcg agccaagtgt aacagagttg gacaagcttc
      901 cttatacgac cgctttctat atcggactct tccaagttct tgctctttta ccagggacta
      961 gccgttcagg tgcaacgatt gtcggtggtt tgttaaatgg aaccagtcgt tcagttgtga
     1021 cagaatttac cttctatctt gggattcctg ttatgtttgg agctagtgcc ttaaagattt
     1081 tcaaatttgt gaaagccgga gaactcttga gctttgggca attgtttttg ctcttggtcg
     1141 cgatgggagt agcttttgcg gtcagcatgg tggctattcg cttcttgacc agctatgtga
     1201 aaaaacacga cttcaccctt tttggtaaat accgtatcgt gcttggtagt gttttgctac
     1261 tttacagttt tgtccgttta tttgtataag aaaaaccttg aaggggcaac tcttcaaggt
     1321 tttatactct tcgaaaatct cttcaaaccg cgtcagcttt atctgcaacc tcaaaacagt
     1381 gttttgagca gcctgcggct agcctcctag tttgctcttt gattttcatt gagctttaaa
     1441 atccagtcat ggtaatcccc aataggcgga cacctctttc tttcttgctt aattcttcat
     1501 agagttgcag ggctatttgg cttatctgac tagcatcttg tgttttttga gcaagacttt
     1561 ttcgtttggt aagagttgaa aagtcctcgt agcggatttt caaaatgaca atttttccag
     1621 ctttttcttg ttgatgtaga ttgagagcga ctttttctga tagaagagtc agctcttttt
     1681 tgatatcttc ctcagcaagg agaatcttcc cgtaggtttt ctccttgccg attgatttac
     1741 ggatgcgatt ggatttgact ggagagttgt gaatgccacg agcctttcga tacagatcat
     1801 agcctagtct accaaaacgg tctattaggg ttacctcagg aacttcaagt aaatcagcac
     1861 cagtaaaaac gcccatttga tgaagacgtt ctactgtctt ttttcctact ccatgaaatt
     1921 tggaaatatc catttgtttg agaaaatcct cagcctgttc aggtagaatc actgtcaaac
     1981 catgtggttt ttgataatca ctcgccattt tagctaagaa tttgttgtaa gaaacgcctg
     2041 cggaagcagt tagatggagt tcttgccaga tatctttttg aatgaggcga gcaattttga
     2101 ccgctgactt gataccgagt ttattttctg tcacatccaa ataggcttcg tcaatgctca
     2161 tgggttcaat caaatctgta tagcgcttaa aaatagctcg aatctggagt cccacagact
     2221 tgtatttctc ataattccct gagataaaga cagcctgggg acaacgttca taagcttcct
     2281 tggaactcat ggcagaatgg acaccaaaag ctcttgcctc ataactacag gtagaaacga
     2341 ctccccgtcc acctgtttgc cgagggtcgc ttccaataat gacaggtttt cctctgagtt
     2401 taggattatc cctgatttcc actgcagcaa aaaaggcatc catgtcaata tggatgattt
     2461 ttcttgacaa atcatttaac aaaggaaaaa tcaacatgcc tagcaccttt ttatactctt
     2521 cgaaaatctc ttcaaaccac gtcagctcta tctgcaacct caaaacagtg ttttgagcaa
     2581 tctgcggcta gcttcctagt ttgcttttcg atttccattg agtgttactg cttattttct
     2641 tttattatac ccttttttct gaaaaaaaga aaaaaggact ttattttttc aaaaatataa
     2701 tacagtttga aataaaatat agactgtttt agaaaagaaa gtgtaaaaat agggaatttt
     2761 cacttgttga aatcggttac tatatggtat acttgtctta tgaatgtaac agatgactgt
     2821 tactagaaaa aagaggacat taatatggtt gttaagacag ttgttgaagc acaagatatt
     2881 tttgacaaag cttgggaagg cttcaaaggc gtagattgga aagaaaaagc aagtgtatca
     2941 cgatttgtac aagctaacta cacaccttat gatggagacg aaagcttcct tgcaggacca
     3001 acagagcgtt cacttcacat caagaaaatt gtagaagaaa ctaaagcaca ctacgaagaa
     3061 actcgtttcc caatggacac tcgtccaaca tctatcgctg atatccctgc tggatttatc
     3121 gacaaagaaa atgaagttat cttcggtatc caaaacgatg aactcttcaa attgaacttc
     3181 atgccaaaag gtggtatccg tatggctgaa actactttga aagaaaatgg atacgaacca
     3241 gacccagctg ttcacgaaat cttcactaaa tatgtaacaa cagttaacga cggtattttc
     3301 cgtgcctaca cttcaaatat tcgtcgcgct cgtcacgcac acactgtaac tggtcttcca
     3361 gatgcatact cacgcggacg tatcatcggt gtttacgcac gtcttgctct ttacggtgca
     3421 gactacttga tgcaagaaaa agtaaatgac tggaatgcaa tcaaagaaat cgatgaagaa
     3481 acaatccgtc ttcgtgaaga agtaaacctt caataccaag cattgcaaca agttgttcgc
     3541 ctgggtgacc tttacggggt tgatgttcgc aaaccagcga tgaacgtgaa agaagcaatc
     3601 caatgggtta acattgcttt catggctgtc tgccgtgtga ttaacggtgc tgctacatct
     3661 ctaggtcgtg taccaatcgt attggacatc tttgcagaac gtgaccttgc tcgtggtaca
     3721 tttactgaat cagaaatcca agaattcgtt gatgatttcg ttatgaaact tcgtacagtt
     3781 aaatttgctc gtacaaaagc ttatgaccaa ttgtactcag gtgacccaac ctttatcaca
     3841 acttctatgg ctggtatggg taacgacggt cgtcaccgtg ttactaagat ggactaccgt
     3901 ttcttgaaca ctcttgacaa catcggtaac tcaccagaac caaacttgac agttctttgg
     3961 actgacaaat tgccatacaa cttccgtcgc tactgtatgc acatgagcca caaacactct
     4021 tctatccaat acgaaggtgt aacaacaatg gctaaagacg gatatggtga aatgagctgt
     4081 atctcatgct gtgtgtctcc acttgatcca gaaaatgaag aacaacgcca caacatccag
     4141 tacttcggtg ctcgtgtaaa cgttcttaaa gcccttctta ctggtttgaa tggtggttac
     4201 gacgatgttc acaaagacta caaagtattt gatatcgaac caatccgtga cgaagttctt
     4261 gaatttgaat cagttaaagc gaactttgaa aaatctcttg actggttgac tgacacttac
     4321 gtagatgcct tgaacatcat ccactacatg actgataggt acaactacga agctgttcaa
     4381 atggccttct tgccaactaa acaacgtgcc aacatgggat tcggtatctg tggatttgct
     4441 aacactgttg atacattgtc agctatcaaa tacgctacag ttaaaccaat ccgtgacgaa
     4501 gatggctaca tctacgatta cgaaacaatc ggtgactacc cacgctgggg tgaagatgac
     4561 ccacgttcaa acgaattggc agaatggttg atcgaagctt acacaactcg tctacgtagc
     4621 cacaaactat acaaagacgc agaagctaca gtatcacttt tgacaatcac atctaacgtt
     4681 gcttactcta aacaaactgg taactcacca gttcacaaag gtgtatacct caacgaagat
     4741 ggttctgtga acttgtctaa acttgaattc ttctcaccag gtgctaaccc atctaacaaa
     4801 gctaaaggtg gttggttgca aaacttgaac tcactttcta gccttgactt tagttatgca
     4861 gctgacggta tctcattgac tacacaagta tcacctcgcg ctcttggtaa gactcgtgat
     4921 gaacaagttg ataacttggt aacaatcctt gatggttact tcgaaaacgg tggacaacac
     4981 gttaacttga acgttatgga cttgaacgat gtttacgaaa aaatcatgtc aggcgaagac
     5041 gttatcgtac gtatctctgg atactgtgta aacactaaat acctcactcc agaacaaaaa
     5101 actgaattga cacaacgtgt cttccacgaa gttctttcaa tggatgacgc cttggatgca
     5161 ttgagctaat caagttcttg aataataaaa aggaaccctc ggtcaaacga ctgagggttt
     5221 tgtgcttggg atagtatgag caattccttc ggcgcaatat gcaatgtttt tgggaaggaa
     5281 tagtggaccg aatctgaaat ataatagatt gaaactagaa tagtacacct ttacttctaa
     5341 aacattctta gaaatcgatt tgactgtcct gatcgatttg tcctattctt atttcatttt
     5401 actatagtcc gctgaaacgg ctcaaacagt gctagaaatt gactggaatt ctctaagtga
     5461 tttgttccga ttttatttca tttcatcata aaaataagat gactggctaa ttgacaatca
     5521 tcttgtttga tactgttaat aaaattcgcg aagtttatct tgattttctt taaaaaattt
     5581 ttctaaccaa tccataccat aagcataact aaaaccttct aatagaacag agaggtcaat
     5641 agtatcaaat cccatgtctt ttaaatattt aaaggtatcg aatggtgaat gaaagttttt
     5701 gtatttaata attgcaccaa tatcttgcaa atcctgctct ctgatactca tcatcttcat
     5761 tcctaacaca tactcaatag ggactactaa aacggtcaga ttctcaaatg agtacaagga
     5821 ttcgcataaa cttaagggag gttgtttgtt catatttgct ttgcaacatg attgttgagc
     5881 cataactctt cgtggatgtt aagattaaac tgttttccta cacgagcaat aatttcattg
     5941 attttctgat tttggtcata aaaagcatca acatcttgtg tggcacgtaa accatgatat
     6001 tctaagacat aaccataatt gttaaagtca gattttcctg aattaatttc ttatttaggg
     6061 cttggaagac cggtttcatt ttatccatgt ttgtatttct ccatcaattt ttgaacattg
     6121 gttaacttag caggtttatt taatgaaatc acatatttat gagttggagt atgctcttga
     6181 aaggcatact tcaagctaat tttttgaaaa cgggttagtt ctttggagtc tagcaacttt
     6241 tctacatctt ggtttgttaa ataagaatag tcttcaaaaa taacttttcg caaatagcga
     6301 aaccaatggc ttgcgttgaa ttgtgattgt ttggatgcct gtatcatata atcgtaccaa
     6361 tccattgtct tcctcctata aaatttagtt tatattattg tagtttatat tcaaaaatgt
     6421 agtttttctt aattagctcg tatctatagg atgatactga aaatcttctt gttgctttaa
     6481 atcacaatcg aaaaattctg tttttcatct tagaaaagaa tgtttagaaa tgtaaaatga
     6541 accttttttc ttatccgaaa accttactaa agtatataat ttaggcagtc aattctgtat
     6601 gataatgttt gtactatcgt cgagtttttg cttgattgcc taacgagata aattttagaa
     6661 gagttttcgg tgtgatttga caagtttctg actggaagga tagttacact agtattgttt
     6721 attaaaatga gcagatagag aaaatttgga atctatttgc ttattatcaa tcgttttttt
     6781 agcttatttg tcttagattg gtatagaact gagctatgga ttaatcttct tctatcttat
     6841 cctgttccta aatatgttgg tagaaaaatg aagcagttgt tacgagtgtc tgtattggga
     6901 aaaattttgt ctatagaatt ctttaaatga tatgaaggct aggaatgcca aaacactgac
     6961 atatttcgtt taaagtctat ccagtctctt caattgtatt tgtagaaatg ctatcagtaa
     7021 tatattcgcg aacactatga tttacaacag tgtggtcgta catctttgta actttattat
     7081 acaacaacca tttacaggtg taaagttgag cagtgtcttt agtaaattta gggacttgtt
     7141 ttgtcatagt tttgatacct gtattcgttg tttcatgagc atttgacgtt tcttttcatg
     7201 taggcatttc aacaattaga atgatatttt tccgaggatg aacttatata ttgtgacttt
     7261 ttagagttat gatgcctctt gatttgacta ccgctatcaa tttcatccac ttttacagtt
     7321 tcatggtttt atgaaccgaa acatctaggt acaggtttta gcatcaattg attgtttttg
     7381 agccatatga agttgaaacg tggagatgct tttcttgtga taacgcccta ttcaaagagg
     7441 aataaccgtt tttggagaga gttcagtact atgtggcgct aaatactata tgtaaaacat
     7501 atattaaaca agatttaact aaggagaatt gtaaaaacaa aaatgagaat ttcatataaa
     7561 gtttattcta ggagtatgta tcttgaataa aaatcgttat ttaagttcag ggttatgatg
     7621 aatgttttta taataataaa atgcagctag aagaaaagtt attttaatat aaatcactca
     7681 acatagagag aaggcggttt cctatatgga agtcgtcttg ttttcatatt gtctaaatac
     7741 gagatatcta ctacaggtta tagttgattt aaacaggtct atagatttct aatatattaa
     7801 ggtgaaataa tatcttgtaa tacattgcta tgttctatga aaaaagcgac gatagctaat
     7861 gcacaagctc ctatacttcc acgatgtttg ttgtaaggta aaatttcaat ttctatatta
     7921 cgagtaaagg gaacgaagtg gagctggtct tggattttat ccctgacttc atgagtgaaa
     7981 ggttgataat taagcaattg actgttgata tagattttat cagcaggatt gatgaggagg
     8041 agatttgcaa tagaagtggc taataaattg actcctttat caatttgttg acgtaaagcg
     8101 gagtcgccta aattataagc cgttaaaagg gtgtctaaat gaatgtcttt ttcagtcttt
     8161 acaaggcttt ttagtacagt tagttgggaa tttttaaata ataattgggc gtgtttgatt
     8221 aaccaagcat ccgaaatata tgtttgtaaa caaccttttt ttccgcattc acaatattgc
     8281 ccattcaatt cgacaatggt gtgtccaatt tctccgatat aaggattttt agaggctcct
     8341 attttttctt ttgtgaaaaa ggaagtgtaa atacctaatc cagcgtgtag gaaaataaag
     8401 ttatcggggg tattgtgtgg attaaaaagg tattgtccta tagccataca atcgatatta
     8461 ttttttacaa taaaaggaaa attgaatctt ttaattacat ttaataaatt aaaagattcc
     8521 catatggggt tgtttgtaat gatacttccg gagtctttgt tataatgtcc aggtattgat
     8581 aagccaaatc caagtaattt tgtttccaaa gggacgtact ctatagctgt ttttatcata
     8641 ttggtaatgg tggaattgat ttctgaaata ggataatctt cattcaaaat ttctgtctcg
     8701 aaaagagttt tcccttgtaa gtcacataga ctgagaaaga tacctaggac gtttatttca
     8761 atacctccaa caacatacgg aatattatct gtgatagaaa tagtttttct acgtcttcca
     8821 gatccggaaa actcgctaaa ttcatcacca gtttcgtata tgagggactg ttcgcttagc
     8881 tcttttatga tgttagtcgt tgttgctgga gtaagtcctg tttcattaac aatatctgta
     8941 cgggatgttg ctggatttcg atatagaaac tccagtatag tggctctatt ttgtaaaaag
     9001 gctgattgtt ttgtaatcat ttgtttcctc ctttggttta ttttatatta aacataagaa
     9061 aaaatcaatt aaaattatta ttttatacaa agaaaaaaat attgtaaaaa caacaaaaaa
     9121 tatattgaca acgctttctg ttagtggtat atttaattta taaaaaataa aaaaaggagt
     9181 tccggtgatg aacaatattt tagcgttttt agaaacaaaa gtcgctccgt ttggtgaaaa
     9241 agttggcaac caacggcatt tgaaagctat tcgtgaagga tttatgatgg caatgccttt
     9301 gattttagtc ggatctttat ttcttattct aatcagttgg cctcaagagg attttacaaa
     9361 ttggctgaat agtgttggat tgctaagtat cttgacaact atgaatcagt caacagtagc
     9421 gattatctcc ttggtcgctt gtttcggtat tgcctacagg ttgtcggaag gatatggtac
     9481 agatggtccg tcggcaggga tcatagcctt atccagtttt gtattgatgg cacctcgttt
     9541 ttcgagtatg gtttatgata aaaatgggga gcaggtcaag cagttatttg gcggcgcaat
     9601 accattttct agcctgaatg catcttcttt gtttatggcg attactattg gattggttac
     9661 agcagagatt tatcgtatgt ttatccagcg cggaattacg ataaaaatgc caagtggtgt
     9721 cccagatgtg gtaagtaaat cattttcagc tcttttacct ggctttacta cttttgtttt
     9781 gtgggctctg gtcttaaaag gtcttgaagc ggcaggagtt gcaggaggtc tcaacggact
     9841 cctaggtgca attgttggaa caccgcttaa gttaattgca ggaacgcttc caggtatgat
     9901 tctatgtgtt attgtaaact cattcttttg gttctgtgga gttaatgggg gacaagtttt
     9961 aaatgctttt gtagatccag tttggttaca atttactaca gaaaaccaag aagctgtggc
    10021 tgcaggacaa acactccaac acattattac attaccgttt aaagatttat ttgtatttat
    10081 tggtggcggt ggagcgacta ttggtcttgc gatttgtctc ttcctattta gtaagagtcg
    10141 tgcgaataaa acattaggta agctagctat tataccgtct atttttaata tcaatacagc
    10201 tattctattt acgtttccaa cagttttaaa tccgattatg ctgattccgt ttattgctac
    10261 tcctacaatc aatgccttaa ttacctatgt atcaatggct gtaggattag taccctacac
    10321 aacaggtgta atccttccgt ggacaatgcc accgatcata ggaggcttcc ttgcgacagg
    10381 agctagttgg cgaggagctc tattacaagt tgttttgatt ttggtttctg tagcaattta
    10441 ttatccattc ttcaaaattg cagataaacg caatcttgaa aaagaaaaag ctactgttgg
    10501 agggaaataa gatggttatc agagtatttg atcagcagaa aaatacttat tctagctttg
    10561 ccttagagga attaagttac tatataaatc gggtctttaa gactgacata gaacttgtcg
    10621 aggagaagga agcggatatt tttgtaggat tagtcaataa agaggataga aaagaccatg
    10681 ttcttatctc attagacaag ggtaagggga gaattgagtc taatacaatt gtaggtttgc
    10741 ttattggaat ttaccgaatg tttcatgaat ttggggttgt gtatactaga ccagggcgcg
    10801 gacatgactt tgttccagag ttacgatttg aagatttttt agataaagag ctatctatag
    10861 atgaaacagc cagttactat cataggggag tatgtataga gggagcagat tcatttgaaa
    10921 atatactaga tttcattgat tggctaccta agattgggat gaacagtttt ttcattcagt
    10981 ttgaaaatcc ctattctttt ttgaaacgtt ggtatgaaca tgagtttaat ccatacctaa
    11041 ataaagaaaa attctcaaat gaattagtac aagaattgag tgataggttg gataaagaat
    11101 tgcaaaaaag aggtcttatt catcatcgtg ttggtcatgg atggacaggt gaggttttag
    11161 gttactcttc aaaatttggc tgggaatcag gtcttagtat ttcagaggag aagaaaccct
    11221 atgtcgctga aataaacggg aaacgagaat tatttaatac ggctccgatt ttaaccagtc
    11281 tggatttttc aaatccagat gtggcggata agatggtaga aattatcaag gattatgcca
    11341 agaaaagacc tgatgttaac tacttacatg tatggttgtc ggatgctcgt aataatattt
    11401 gtgaatgcga aaactgtaga caagaattgg tttcggatca gtatattcgt attctcaatc
    11461 aattggatag ggctttaacg agtgagggat tagatacaaa gatttgtttt ctgctttacc
    11521 atgagttgtt atgggcgcct cagaaagaaa aattagataa tcctgaacgc tttaccatga
    11581 tgtttgcacc gattacaaga acatttgaaa tgagttatgc agatgtagat tttgacaatt
    11641 ccatacctac gcctaaacct tatctgcgta ataaaattat acttccgaat tctcttgagg
    11701 aaaatttatc ttatcttttt gagtggcaaa aaacatttaa aggagatagt ttcgtatatg
    11761 actatccttt agggcgtgct cattatggcg atttaggcta tatgaaaatt agtcaaacca
    11821 tttacagaga tgtatcttat ctttctaacc tacatttgaa cggttacatt tcgtgtcaag
    11881 aattacgtgc cggattccct cataattttc ctaattatgt tatgggggaa atgctctgga
    11941 agaagacaag aagttatgaa gaattgattg aagaatactt ttctgctttg tatgggtcaa
    12001 attggcagtc tgttgttgaa tatttagaaa aattatccag ttattcctca tgtgattatt
    12061 ttaatgcaat tggcagtcgt caaaatgatg ttttagcgaa tcattattat atagcttaca
    12121 atctagctga taattttttg ccaattattg aggaaaatat ttctaagtta ttaaatagtc
    12181 aaaaggatga atggaaacag ctcagttatc atcgtgaata tgttgttaag atggcgaagg
    12241 ctttatatct tcaagcaacc ggaaaaacaa ggcaagctca agatgaatgg agaaatgtgt
    12301 tgaattatat ccgtgggcac gaattgctat ttcaatctaa tttggatgtt tatcgtgtaa
    12361 ttgaagtagc aaaaaattac gctggtttcc acttataaat cataagtata gaaaatgaac
    12421 caaggtattc agagaagatt gatcctaaat attatgaaat ttaaggattt ttaagatatt
    12481 tagggtcgac tttctattta tatcgtagcg aagtcatttt aataatgatg tgtaaaagat
    12541 ggatcaagat tgaggaggaa gaaagatgaa atcaaaagaa gaaataaata tgcttggttt
    12601 tacaattgtc gcttacgcag gagatgcaag gtcagatttg atggatgctt tggcgtttgc
    12661 gagagatgga tattttgaac aggcaagaga attggttgag tctgcaaacg actcaatagt
    12721 gtctgcccat cgagaacaga ctaatttatt agcggaggag gcatctggag ataattttga
    12781 agtgagtttt atcatgattc atggtcaaga taccttgatg acaacgatgc tattgtatga
    12841 tcaggtcaag ttttttattg atgaatatga acgaattcga aagattgaag aacatattgg
    12901 tttgcaatga ggattagtca tggaaaattt acaggttaaa gccttaccga aggagttttt
    12961 attaggagct gctaccgctg cttatcaagt agagggtgca actagggtag atggcaaagg
    13021 aacaaatatg tgggatgttt atttgcaaga aaacagtccg ttcttaccag atccagctag
    13081 tgatttttat tatcgttacg aagaggatat aactttggcg gcagaacatg gtttgcaggc
    13141 tttgcgttta tctatttctt gggttcgtat atttcctgat atagatgggg agcctaatat
    13201 attagctgtt cgttattacc atagagtctt tcagtcttgc ttaaaacata atgtgattcc
    13261 gtttgtttct ttacatcatt ttgattcgcc tcagaaaatg ttagaaacag gggattggtt
    13321 gaatagagag aatattgatc gtttcatacg atatgctcgc ttttgtttcc aagaatttac
    13381 agaagtcaag cattggttta caatcaatga actgatgtct cttgctgcag gtcaatatat
    13441 aggaggtcag tttcctccaa atcatcattt tcaattatct gaagcaattc aagcgaatca
    13501 taatatgttg ttggcgcatg ctcttgcagt cctcgaattt catcaattag gaattgaggg
    13561 agagataggt tgtattcatg ctttaaagcc aggctatcct attgatgggc aaaaagaaaa
    13621 tattttggca gctaaacggt atgatgttta taataataaa tttctattag atggaacttt
    13681 tttgggctac tacagtgagg acacgctttt tcacttgaat caaatattgg aagctaataa
    13741 ttctagcttt attattgaag atggtgattt agaaattatg aagagagctg cagctcttaa
    13801 tacgatgttt gggatgaatt attatcgttc agaatttatt cgtgaataca aaggtgaaaa
    13861 tagacaagaa tttaattcaa caggaataaa aggacagtct tcttttaaat taaatgctct
    13921 aggtgaattt gtaaaaaaac ctggtattcc gacaacagat tgggattgga atatttatcc
    13981 tcaagggtta tttgatatgt tgcttcgtat caaagaagaa tatcctcaac atccggtcat
    14041 ttatttaact gaaaatggta cagcccttaa agaagttaag ccagagggcg agaatgatat
    14101 tattgatgac agtaagagaa tccgttatat tgagcaacat ttacacaaag ttttagaggc
    14161 tcgagataga ggagtcaata ttcaaggcta ttttatatgg tctttgcaag atcaattttc
    14221 ttgggcgaat ggctacaata agcgatatgg tcttttcttt gttgattatg aaacacagaa
    14281 gagatatatt aagaaaagtg ctctttgggt aaaagggcta aaacggaatt aaggttagcg
    14341 atttgactga tgtttaatat attttaacta tgagcttaaa ttttttacag gaggagtttt
    14401 tatggataag ttagtcgctg ccattgaaaa gcaacaaggg aaatttgaaa aaatttctac
    14461 taataattat atgatagcta ttaaagatgg atttattgct actatgcctt taattatgtt
    14521 ttcaagcttt ttgatgatta ttattatgat tcctaaaaat ttcggagtag agttaccgag
    14581 tccagctatt gcctggatga ggaaagtgta tatgctaacc atgggagttt tgggtattat
    14641 tgtttcaggg acagttgcaa agtcattggc tggaaatgtt aatagaaaaa tgcctcctgg
    14701 aaaggtaata aatgatactt ctgcaatgtt ggcggccata tgtggctatc ttgtattaac
    14761 tgtaacgctt gtagttgatg agaaaacggg atctacaagt ttgtcgacaa actatttagg
    14821 atctcaagga ttgataactt cgtttgtcag tgcctttatt actgtaaatg tttaccgatt
    14881 ctgtattaag cgagacatta ctattcattt acctaaggaa gttcctgggg ctatatcaca
    14941 agcttttaga gatatttttc ctttttcttt tgttttactt attagtggtt tgttagatat
    15001 tgtatctcgg tttagtttag atgttccttt tgcccaagta tttcaacaac tattgactcc
    15061 tatttttaag ggggcagaat catatcctgc tatgatgttg atttggttta tgtgtgcttt
    15121 gctttggttt gttggaattc atggaccatc tattgtctta cctgctgtta cagctttaca
    15181 actgagcaat atggaagaga atgctcaact tcttgcaaat gggcagttcc cttatcattc
    15241 tttaacacct aatttcggga attatatcgc tgctattgga ggaacggggg ctacctttgt
    15301 tgtaccattt attttgattt tctttatgcg gtctaaacaa ttaaaatcgg taggtaaagc
    15361 tacaattact cctgttttat ttgcggtaaa tgaacctctt ctatttggta tgcctgttat
    15421 tttgaatccc tatctttttg tccctttttt gatgactcca ccagtgaatg tatttctagg
    15481 aaaggtattt attgatttct ttggaatgaa tggattttat atccagttac cttgggcctt
    15541 tcctggtccc ttgggattgt taattggaac gaattttcaa cttatctcct ttgtattttt
    15601 atctttgatg ttagttgtcg acatattgat ttatttgcca ttctgtagag cgtatgatag
    15661 acagttactg gtgaaagaag atattgcaag ctcaaatgat attattttag aggaggatac
    15721 aagtgaaata atgcctggtg agatagatgt aataaaaagt aaggagttga aagtactggt
    15781 tctttgtgca gggtctggaa caagtgcgca attagccaat gcaattaacg agggcgctca
    15841 attagcagaa gttagagtga ttgcgaattc aggagcgtac ggagctcatt atgatattat
    15901 gggtgtttat gatttaatta ttctggcccc acaagttcgg agttattata gagagatgaa
    15961 ggtggatgca gaaagattag atattcagat agttgctacc agaggaatgg aatatattca
    16021 tttaacaaag agtccaagta aagccttaca atttgtattg gagcattacc aagctgtgta
    16081 gtaagttttt ccatctttta tttgagtaaa gattttgctt acagataggc ttggatttaa
    16141 aaacgttccc ccttttttaa tataagaatc cctctttcac aattgtaaaa agagggattt
    16201 tgtattttat ctcttagacc aagttctctt cataaagaga aggaggattg ggtaaatctc
    16261 caagcgccct gcaatcattg caaaggatag gagaattttt gagatgggac taaagattga
    16321 gaaactagaa gtggttccta gaataggccc gatattattg aaacagctaa agacagcgct
    16381 ggtcacgacc agaaaatcat tgctatctag gctgacaata aagataagcg ctagcaaaat
    16441 catagcatag atgacaaagt acttgagaat cttatgctgg gtatctttgt caatcaccgt
    16501 tttattaaca tggagggtca aaacacggtg gggcgatagg attgacaaaa tttggttttt
    16561 ggcaattttt gaaaggatga ggcctcgaat aatcttgagt ccacctgcag ttgatccagc
    16621 agagccaccg attgccatga ggaaaaggag gataaactgg gagaagaggg gccagttggt
    16681 aatatctcca tatccaaaac cagttgttgt aatgatgttg gaaacctgga agaaggtcat
    16741 ttcaaagctc tttgaaaacc ctgggtagag gtagagggtg ttgaggctaa tcaagcctgt
    16801 agaaaccagt acaatgacca agtaagccct aagctcttca tctccaaaga aggccttgat
    16861 gcgacggagc atgaggtagt agtagaggtt gaaatttact ccaaaaacca gaactccgat
    16921 actgaccaga taggtaatca gtgagctgcc atagtgggca attccgtcgt tatagacggt
    16981 aaagcctcca gttcccgctg tccccatagc aatgacaaaa ctatcgtaga gaggcatacc
    17041 agctagataa tagatgatga caaagaggga gaagagagct agataaagga gatagagaat
    17101 ctgggcagtg ttttttagtt tggatacaac cttgccaaaa acaggacctg gaacctcagc
    17161 cttcatcacc tctaggtggc tatttttggc attgtccata atagcaagtg caaaaacaag
    17221 cactcccatc cctccaatca agtgggtaaa acttcgccag aagaggaggg aacgactgag
    17281 aactgaaacg tcgttcaaaa tacttgctcc agtagtcgta aagccggaac taatctcaaa
    17341 aaaggcatca ataaggctgg ggatttgccc agaaaagaca aaggggagac caccaaagaa
    17401 agaccaaagg atccaacaga gggcaacgat caagactccc tccttggcat aaatccgttg
    17461 attttttggc ttctgtaaac tccctgaacc gcctaacaat acgagaatcc ctatggtcga
    17521 aaagagggct gtaaagactt ggctcgattc acggtaatag acagcgatag ccacaggaac
    17581 caagaggaga acagcttcaa tcaaaagtaa ctttgaaagg aggtaacgaa tcatactttt
    17641 attcatttct tacctcgcaa tcaagtcata aatcttggtg atgtttggca acaaggttgt
    17701 tactaggagc ttgtctccaa cttccaacat atcctcccca gttgggaaaa tagtcttgcc
    17761 ctttcgaata atggctgcaa taagaacccc ttttttcaat ttcagttgag aaagaggttt
    17821 ggcagtcatt ttattggctt ccttgatatg gaattgcagg gtttcgattt ggccattggc
    17881 tagatggtgc atggcttgaa ggtctgaata ctgggcatta actcgaccac gaataaagtg
    17941 cataatcgta tctacagcga tgcttttagg tgtgatgata cttgaaaaat caggcgcatt
    18001 gataatctcg aggagactgg tacgattgac cttagtaata tttttctgta cacctaccct
    18061 gtcaaggaac atagatgtaa tcagattttc ctcatcgact cctgttagag tcgcaacggc
    18121 atcatagtgt tgagcacttt cttccagcag gatatctttt gcggttccat ctccttgaac
    18181 gatgtagaga tttgggaatt tctcgctaaa gaagctggcg atttcaggat tgatttcaat
    18241 gacttttgta tcgatacgac tatctttgag aataccaagt agataatagg caattctacc
    18301 tgccccaacg atgagaaggc tcttcacggc gcgtgattta aaataattat ggaagagtat
    18361 catatcgaca cggttaccag tgacaaagat tctatcttta tcctgtacag tcatgtcacc
    18421 gcttggaatg ataatttgat gatccctctc tatcgcacag acaatgacat taccaaattt
    18481 tttacgaaaa tcagaaatgg gcatttggca aagaccgctg gtggacttga cgacaaattc
    18541 catgaggcta acgcgtccac cagcaaagcg ttcgacagac agggcgttgg ggaagtcaat
    18601 gatattcgcg atagcacggg cagccaagag ctcaggatta acgataagag aaaaaccgag
    18661 aatattcttt tccttgaaat aagagttaga atattcaggg ttccgcaccc gaacgatagt
    18721 ttctttagct cccattttct tggctagaac tgctgcaatc atgttgactt catcgtgctc
    18781 agtcagggcg ataaagatat cacaatcttg gacgctggct tgctcaagaa tggcaaaatc
    18841 ggccccgtta ccaaggatac caatgatatc aaagcgactg acaatatgat tgagaacagc
    18901 ttcgtcttgc tcaatcagca aaacatcatg cttttctgca accaaggagc gacagagggc
    18961 aaaaccaact tttccccctc cgacaaggat aattttcata ataaaaccta ctttttcatg
    19021 atgtaactat catacccttt ttcaagaaaa aatgcaccta ctagctaata acaagagctt
    19081 ttagtgaaaa ttcgctataa gataaaacta taccctaacc aattgaaata gctattagcg
    19141 actttctctg aaatatggta tgataaagga tatacaagga gataaaatga ataataattt
    19201 actggtatta caatcagact ttggtctggt tgatggtgcg gtatcggcta tgattggagt
    19261 ggctttagaa gagtctccaa ccttaaaaat ccatcacttg acgcacgata tcacgcctta
    19321 taatattttt gaggggagct atcgtctctt tcagacggtg gattactggc ctgagggaac
    19381 gacgtttgta tcggttgtcg atccaggtgt cggttcgaaa cgtaagagtg tagttgccaa
    19441 gactgcaaaa aatcaataca ttgtcacgcc agataatggg acgctttcct ttatcaagaa
    19501 acacgttggc attgtagcca ttcgtgagat ttctgaggtg gccaataggc gtcaaaacac
    19561 agagcattct tataccttcc acggtcgtga tgtctatgcc tatactggtg ctaaactggc
    19621 cagtggtcac attacttttg aggaagtagg gccagagctc agtgtggaac agattgtaga
    19681 gcttccagtc gtagcgacca tcatagaaga tcatctggtg aagggagcca ttgatattct
    19741 ggatgtgcgt ttcggttcgc tttggacctc tatcacacgg gaagaatttt acaagttgga
    19801 accagaattt ggtgatcgtt ttgaagtgac catctatcat gctgatatgc tggtctatca
    19861 aaatcaggtt gtctatggca aatcatttgc agatgtgaga attgggcaac ccatccttta
    19921 catcaactct ctctatcgtt taggtttggc tatcaaccaa ggttcctttg ccaaggccta
    19981 taatgtaggt gtcggttcat cttggaccat tgaaataaag aaaatagaag gataaaatag
    20041 gagaatagta tggaaatcaa atttacaatt aaacaagttg ttgctgtcgg aattggcgct
    20101 gccctctttg tcgtcatcgg gatgatcaac attccaaccc ctgttccaaa tacaagcatc
    20161 cagcttcagt atgcggtaca agcgctactt tctattattt ttggaccgat tatcggtttg
    20221 cttgttgggt tgattggtca tgcaatcaag gactctcttg ttggttatgg tctatggtgg
    20281 acttggatta tcgctagcgg actctttggt ttagttgtgg gactttttag aaagtacgtt
    20341 cgcgtgatca atggtgtttt tgactggaaa gatattctta tttttaacct cattcaacta
    20401 cttgcaaatg cccttgtttg gggtgtcttg gcaccacttg gagatgttgt gatttatcaa
    20461 gaagcggcag aaaaagtatt tgcacaagga attgttgcgg gaattgccaa tggtgtatct
    20521 gtagctattg caggaactct tctcttactt gcctatgcag gaacccaaac tcgtgcagga
    20581 agtttgaaaa aggactaata ctcaatgaaa atcaaagagc aaactaggaa gttagccgca
    20641 ggttgctcaa aacagtgttt tgaaattgtg gata
//
LOCUS       DAVBEM010000041        20158 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVBEM010000041 DAVBEM010000000
VERSION     DAVBEM010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20158
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.041"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            63..527
                     /locus_tag="VQ548_001527"
     CDS             63..527
                     /locus_tag="VQ548_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HET2654356.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            685..1110
                     /gene="lacA"
                     /locus_tag="VQ548_001528"
     CDS             685..1110
                     /gene="lacA"
                     /locus_tag="VQ548_001528"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HET2654357.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1141..1656
                     /gene="lacB"
                     /locus_tag="VQ548_001529"
     CDS             1141..1656
                     /gene="lacB"
                     /locus_tag="VQ548_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HET2654358.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1667..2596
                     /locus_tag="VQ548_001530"
     CDS             1667..2596
                     /locus_tag="VQ548_001530"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HET2654359.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDDQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKLVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLEELKEVLQESLFTGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAGLLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2598..3578
                     /gene="lacD"
                     /locus_tag="VQ548_001531"
     CDS             2598..3578
                     /gene="lacD"
                     /locus_tag="VQ548_001531"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HET2654360.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKILVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            3812..4648
                     /locus_tag="VQ548_001532"
     CDS             3812..4648
                     /locus_tag="VQ548_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET2654361.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENH
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALIQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4684..5001
                     /locus_tag="VQ548_001533"
     CDS             4684..5001
                     /locus_tag="VQ548_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2654362.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5003..6697
                     /locus_tag="VQ548_001534"
     CDS             5003..6697
                     /locus_tag="VQ548_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2654363.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERSGKSNDELKEKVAANFNTAKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            6906..8312
                     /gene="lacG"
                     /locus_tag="VQ548_001535"
     CDS             6906..8312
                     /gene="lacG"
                     /locus_tag="VQ548_001535"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET2654364.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPLDPKNPSDVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8355..8537
                     /locus_tag="VQ548_001536"
     CDS             8355..8537
                     /locus_tag="VQ548_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HET2654365.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLFLNFINPEE
                     WDTISFDSDFMPFQQS"
     gene            complement(8815..9576)
                     /locus_tag="VQ548_001537"
     CDS             complement(8815..9576)
                     /locus_tag="VQ548_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2654366.1"
                     /translation="MLKQEKLAKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(9758..10720)
                     /gene="nrdF"
                     /locus_tag="VQ548_001538"
     CDS             complement(9758..10720)
                     /gene="nrdF"
                     /locus_tag="VQ548_001538"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HET2654367.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(10908..13067)
                     /gene="nrdE"
                     /locus_tag="VQ548_001539"
     CDS             complement(10908..13067)
                     /gene="nrdE"
                     /locus_tag="VQ548_001539"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HET2654368.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(13148..13366)
                     /gene="nrdH"
                     /locus_tag="VQ548_001540"
     CDS             complement(13148..13366)
                     /gene="nrdH"
                     /locus_tag="VQ548_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HET2654369.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            13717..13980
                     /locus_tag="VQ548_001541"
     CDS             13717..13980
                     /locus_tag="VQ548_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HET2654370.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            13986..15719
                     /gene="ptsP"
                     /locus_tag="VQ548_001542"
     CDS             13986..15719
                     /gene="ptsP"
                     /locus_tag="VQ548_001542"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HET2654371.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            15974..18424
                     /gene="phtA"
                     /locus_tag="VQ548_001543"
     CDS             15974..18424
                     /gene="phtA"
                     /locus_tag="VQ548_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET2654372.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYHF
                     IPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSN
                     SSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKE
                     NVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDL
                     LAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYV
                     TPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVK
                     GEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLF
                     ATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVP
                     QVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKL
                     LALLKGSNPSSVSKEKIN"
     gene            18582..>20158
                     /locus_tag="VQ548_001544"
     CDS             18582..>20158
                     /locus_tag="VQ548_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2654373.1"
                     /translation="MKINKKYLAGSVATLVLSVCAYELGLHQAQTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSTNDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWLPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEKRIARIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPS
                     NPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLG
                     AKKTDLPSSDREFYNKTYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKL
                     VDDILAFLAPIRHPERLG"
BASE COUNT         6438 a         3612 c         4158 g         5950 t
ORIGIN      
        1 aactagaatt ctagttttgc aggaagtcta ataaagaaac tagcaaggtc aggccttact
       61 ttattggtgg acatccagga tttaattgtc ttctacttga tgatgaagtc tatgaagatt
      121 attatctaga gtttgagaaa gaagagattt gctctgttcc acgtcctttc ccagaaacag
      181 gtatgttgga tttccaagat agaagtccat ggctagaggg acaaaaagaa atagatctta
      241 gttatgatct tttcagcaca gatgcagtga ctttggatga attgcaatct cgaacaattg
      301 cccttcgttc tcttaaacat gataagggat tgaaagtgca ttttgcagaa tttccaaacc
      361 tcatcatctg gtcaactttg aacaagggac ctttcattac ctttgaacca tggtctggct
      421 tgtcaacatt ccttgaagaa ggagatcatt tagaagataa gaagaatgtt tgtctcttag
      481 aagccaatca ggttgaagaa ttagggtttg agatagaagt tttataaaaa aagtaaaaaa
      541 taaataacaa aaacaaacac aaactgttga cttcttcaaa caatagtagt atattatgtt
      601 tgtgaggact aattgactgt tttttaaaga cagccaatac actgctggaa tccagcatag
      661 aaaaaataaa aaggagtata caatatgtct attgttatcg gtgcagatgc tgcaggtttg
      721 agattgaaag aagttgtgaa agacttctta gaaaaagaaa acttccacct tgtggatgtt
      781 acagctgaag gtcaagactt tgttgatgtg actctcgctg ttgctgcaga agtaaacaaa
      841 gaagaacaaa accttggtat cgtgattgat gcttatggag ctggtccatt tatggttgca
      901 actaagatca aaggaatggt tgctgcagaa gtatctgacg aacgttcagc ttatatgact
      961 cgtggccaca acaactcacg tatgatcact atgggggcac aacttgttgg tgatgaattg
     1021 gctaaaaaca tcgctaaagg atttgttaat ggtaaatacg acggtggacg tcatcaaatc
     1081 cgggttgaca tgttgaacaa aatgggctaa ttagattaca gtaagaaagg taagttaaaa
     1141 atgagaattg caattggatg cgaccacatc gtaacagatg aaaaaatggc ggtttcagaa
     1201 tttttgaaat caaaaggata tgaagtcatt gactttggta catatgacca tacacggact
     1261 cactacccaa tctttggtaa aaaagtaggg gaagctgtaa ctagcggcca agctgatctt
     1321 ggggtatgta tctgtggtac tggtgttggt atcaacaacg ctgtaaataa agttccaggt
     1381 gttcgttctg ccttggttcg tgatatgaca acagcccttt atgctaaaga acaattgaac
     1441 gctaacgtta tcggctttgg tggtaagatt actggtgaat tgcttatgtg tgatatcatc
     1501 gaagctttca ttcatgctga atacaaacca tctgaagaaa acaagaaatt gattgcgaaa
     1561 attgaacacc ttgaaagtca caatgctcaa caaacagacg caaacttctt tacagaattc
     1621 cttgaaaaat gggatcgcgg agaataccac gactaagagg tgacctatga ttttaacagt
     1681 cacaatgaac ccatccattg atatttccta tcccttggat gagttgaaga ttgatactgt
     1741 caatcgtgtg gtggatgtaa ccaaaacggc tggtggtaag ggacttaatg ttacccgagt
     1801 actttcagaa tttggtgatt ctgttcttgc tactggttta gtgggtggca aacttggtga
     1861 gtttttggtt gaacatatcg atgatcaagt aaagaaagat ttcttttcta ttcagggaga
     1921 aactcgtaac tgtatcgcta ttctccacgg tgacaaccaa acagaagttc ttgaaaaagg
     1981 tcctgaagta ttggaacagg aaggtcaaga ctttttggaa catttcaaaa aactcttgga
     2041 gtcagttgaa gtagtagcca tctcaggtag tctgccagct ggccttccag ttgattacta
     2101 tgcgagcttg gtagagcttg ctaatcaagc tggcaagcta gtagtcttgg actgctctgg
     2161 tgcagcactt caggcggttc ttgaatcacc ccataaaccg acagtaatca aacccaataa
     2221 tgaggaattg tctcagcttc taggaagaga agtttctgag gatttggagg aattaaaaga
     2281 agtccttcaa gaatctttgt ttacagggat tgaatggatt atcgtttcac ttggtgccaa
     2341 cggtactttt gccaaacatg gtgacacttt ctacaaggta gatattccta gaattcaggt
     2401 ggtaaatcct gttggatctg gagactctac tgtggcagga atttcttcag gacttcttca
     2461 caaagaatcg gatgcaggat tactcatcaa ggcaaatgtc cttggtatgc tcaatgctca
     2521 agaaaaaatg actggtcatg tcaacatggc caactatcaa gctctatatg atcaattaat
     2581 agtaaaagag gtataaaatg gctttaacag aacaaaaacg tgtacgctta gaaaaacttt
     2641 ctgatgaaaa tggtatcatc tcagctcttg catttgacca acgtggtgct ttgaaacgcc
     2701 tcatggctca acaccaaaca gaagaaccaa ctgtggccca aatggaagaa cttaaaatct
     2761 tggtagcaga tgaattgact aaatacgctt catctatgct tcttgaccct gagtatggac
     2821 ttccagcaac taaggctctt gatgaaaaag ctggtcttct ccttgcttat gaaaaaacag
     2881 gttatgacac aacaagcaca aaacgcttgc cagactgctt ggatgtttgg tctgcaaaac
     2941 gtattaaaga agaaggtgca gatgcagtta aattcttgct ttactatgat gtagatagct
     3001 cagacgaact caatcaagaa aaacaagcct acatcgaacg catcggttct gagtgtgtgg
     3061 ctgaagatat cccattcttc cttgaaatcc ttgcttacga tgaaaaaatt gcggacgcag
     3121 gttctgtaga atacgctaaa gtaaaaccac acaaagttat cggtgctatg aaagtctttt
     3181 cagacccacg ttttaacatt gatgtcttga aagttgaagt tcctgttaac attaaatatg
     3241 ttgaaggctt cgctgagggt gaagtggttt acacacgtga agaagcagca gccttcttca
     3301 aagcgcaaga tgaagcaacg aacttgccat acatctactt gagtgctggt gtatcagcta
     3361 aactcttcca agatactctt gtatttgctc atgaatcagg tgcaaacttt aacggagttc
     3421 tttgtggtcg tgctacatgg gcagggtcag ttgaagctta catcaaagat ggtgaagcag
     3481 cagctcgcga atggcttcgc acaactggat ttgaaaacat tgatgagctc aataaagttc
     3541 ttcaaacaac agcgacttca tggaaagaac gtgtgtaaga aagtcctcct agtttaggaa
     3601 catgaatcta aaaaaattta aaaaaagttg tatgtaaagg tttacaaaat aacttacttg
     3661 tgctatactt aaatcacaag ttaatacaag gtgagtgtta ctaagtaata ttaggcatga
     3721 tcacaggtga attagaaatc agctgatttt ctagttcatt tgtggtcatt ttttgtactc
     3781 atataccttt aagatataaa aggaggttga catgtatcga attctaaatc caatgaatca
     3841 caatgtctcg cttgtcagaa atgataaggg agaagaggtg attgtaattg gtaaggggat
     3901 tgcattcgga aagaagaagg gggatttgat tgctgaaaat catgttgaga aaatctttcg
     3961 gatgaagacc gaagagtcca gagaaaactt tatggctctt ctcaaagatg ttccgcttga
     4021 ttttatcaca gtgacctatg aaatcattga taagctatca aagaaatatc attatccgat
     4081 tcaagagtat ctctatgtaa ccttgacaga tcatatttac tgttcttatc aagctctaat
     4141 tcaaggaagg tacaaggata gtaatctgcc agatatttct gctaagtatc ctgtcgcttt
     4201 tcaaatcgca aatgaagctt ttgaaattta ccgtcagaag ctagcagatc attttcctga
     4261 ggacgaaatt attcggattg cttatcattt cattaatgct gaaggtgaaa atgaagtgga
     4321 acttgtggag tcgattgata agaggaaaga aattctcagg aatgttgaag aagttttaac
     4381 ggactatgca attcaacgaa ctaaaaagaa taaccatttc tatgatcgct ttatgatcca
     4441 tttgaattat ttcttggatt atttagacag atctagagat gataaccaat cacttctgga
     4501 tatggaagat catattaaac aatcctatcc aaaagccttc gagattggtt ccaagatcta
     4561 tgatgtgatt acgcaacata cgggtcttga tttgtataaa agtgaacgag tttatctagt
     4621 tctacatatc caacgtttat tgtcataaaa atttatttaa aactatataa ggagaattct
     4681 atcatgaata gagaagaagt aacattgtta ggttttgaaa tcgtagccta tgctggcgat
     4741 gctcgttcaa aactattgga agccttgaag gctgctgaag ctggtgattt tgaaaaagcg
     4801 gacgctctgg tagaggaagc tggtagctgt attgcagagg ctcaccacgc gcaaacaagt
     4861 ctattgacta aggaagcttc tggtgaggac ttagcgtata gtgtgaccat gatgcatggt
     4921 caagatcact tgatgacaac tatcttgtta aaagacctaa tgcaccattt aattgaactt
     4981 tacaagagag gagttaaata aaatggataa gttaataatt tttattgaga aaggaaagcc
     5041 tttctttgag aaattatcga gaaatatata cttaagagcg ataaaagatg gttttatttc
     5101 cagtatgcca gcagtattat tctcaagtat ttttatacta atagctgctg tgcccaatat
     5161 ttttgggttt aaatggtctg atgaacagtt agcttttatt ttgaaacctt acaactactc
     5221 aatggggatt ttagctctct tagtagctgg gacaactgca aaatcgttaa cagattcagt
     5281 taatacacgt agtatggaga aaaccaacca aatcaactac atgtcaactt ttttagcagc
     5341 tgttgttgga ttgttaatac tggcagctga tccaattgaa ggtggatttg ctaatggtct
     5401 tttaggtact agaggattac ttactgcatt tttggcagct tttattacag taaatatcta
     5461 taaagtatgt attaaaaata atgtaaccat tagacttcct gaagaggttc caccaaatat
     5521 tgcacaagtt tttaaagatg ttattccgtt tgccttatct gttctttcaa tatatggatt
     5581 ggatttaatt gttagaaata tttttggtac aaatgtagca gaatctgttg gtaaaatatt
     5641 agcccctcta ttttcagcta ctgatggtta tatcggttta gctattgtat ttggtgctta
     5701 tgctttcttt tggtttgttg gaattcatgg gccatctgtt gtagaacctt taattgtagc
     5761 tatcagttat gcaaatatag aagctaatgt tcagcttgtg caagctggta tgcacgcaga
     5821 taaaatttta aatccagtta ctcaaacttt tgttgtaaca atgggtggta ctggtgcaac
     5881 actagtagtt ccatttatgt ttatgtggtt atgtaaatca aaaagaaata gaattgtcgg
     5941 acgtgcgtct gtagttccta ctttctttgg cgtaaatgaa ccaatcctat ttggtgctcc
     6001 aattgtttta aatcctatct tctttattcc gtttgttact gctcctatta tcaatgtttg
     6061 gattatgaaa ttttttgtag atgttctaca aatgaatagt ttcagtatta ttttaccttg
     6121 gacaacacct gctccaattg gtattgttat gggaacggcg ctggctccat tgtcattcgt
     6181 cttggctata actttaatca ttatcgacac tttaatctat tatccatttg ttaaagttta
     6241 tgaccatcaa attttagaag aagaacgttc aggtaagtct aatgatgaat tgaaagaaaa
     6301 agttgctgca aacttcaaca ctgcaaaagc ggatgctatt cttgaaaaag cgggtgtcga
     6361 tgcagcacaa aataccatca ctgaagaaac aaatgtcctc gttctctgtg caggtggagg
     6421 aacaagtggt ctccttgcaa atgctttgaa taaggcagca gcagaataca atgtccctgt
     6481 gaaagcagca gcaggcggct atggtgctca ccgtgaaatg ttaccagagt ttgatcttgt
     6541 tatccttgcc cctcaagttg cttcaaactt tgaagatatg aaagcagaaa cagataagct
     6601 cggtattaaa ctagcgaaaa cagaaggcgc tcaatacatc aaattaactc gtgatggaaa
     6661 aggtgctctt gcattcgtac aagcgcaatt cgattaaggc tagagactct gaaatagtct
     6721 cctatcgtta cggaaatcgc tatggcgaat ttcctattat taattcgtcg gtaaaaagat
     6781 atcgttttta cctcctcatg tcacaattcg gtgacttggt acaagaagtg agatggagaa
     6841 ggatggctca ctgactcctc tcctctcact tttactttat ttaaatcaag aaataggtga
     6901 aaaaaatgac aaaaacactt ccaaaagact ttatttttgg tggcgcaaca gctgcctatc
     6961 aagcagaagg tgctacacat actgatggta aaggaccagt agcgtgggat aaatatcttg
     7021 aagataacta ctggtacact gcagaaccag ccagtgattt ttacaatcga tatccagttg
     7081 acctcaagct agcagaagag tatggtgtca atggtattcg aatttctatt gcttggtcac
     7141 gtattttccc gactggttac ggccaagtaa atgctaaagg tgttgagttt tatcataatt
     7201 tatttgcaga gtgtcacaaa cgtcatgttg agccctttgt aactcttcat cactttgaca
     7261 cgccagaagc tctccactca aatggagact tcttaaaccg tgaaaatatc gaacattttg
     7321 tagactacgc tgccttctgt tttgaagaat ttccagaagt aaactattgg acaaccttta
     7381 atgaaattgg gccaattggt gatggtcaat acttggttgg gaaattccct ccaggtattc
     7441 agtacgacct tgccaaagtc ttccaatcgc accacaatat gatggtgtct catgcgcgtg
     7501 cagttaagct atataaagat aaaggctata aaggcgaaat tggtgttgtt cacgctctgc
     7561 caactaagta tcctttagat cctaaaaatc cgtcagatgt tcgtgcagct gagttggaag
     7621 atattattca caataaattt atcttggatg caacttatct aggtcgctat tcagctgaaa
     7681 cgatggaagg tgtcaaccat atcttatcag tcaatggtgg tagcttggat cttcgtgaag
     7741 aagattttac agcattagaa gcagcaaaag acttgaatga tttccttgga atcaactact
     7801 atatgagtga ctggatggaa gcctttgatg gagaaactga aattatccat aatggtaagg
     7861 gtgagaaagg aagttctaaa taccaaatca aaggtgttgg tcgtcgtgta gctcctgatt
     7921 atgtaccacg tacggattgg gattggatta tctaccctca aggtttatat gaccaaatta
     7981 tgcgtgtgaa gaaagattat cctaactaca agaagattta catcactgaa aatggtctcg
     8041 gctataaaga tgagttcgtc gataacactg tttatgatga tggacgtatt gattatgtga
     8101 aacaacactt ggaggtcttg tctgatgcga ttgcagatgg agcgaatgta aaaggttact
     8161 tcatttggtc attgatggac gtcttttcat ggtcaaatgg ttatgaaaaa cgttacggtc
     8221 tcttctatgt agactttgaa actcaagaac gttatccgaa gaaatcagct cactggtaca
     8281 agaaagtagc ggaaactcag attatagact agtagaatta gtcattagat atagaatttt
     8341 agtgagtcaa aaagatgttc aaagatttta tccaatctat ttatgaaaaa gtttatatta
     8401 taaatttcga aaaatgctct caaataccgt gtttgacgag tgaagaattg aaaagtctat
     8461 ttttaaattt tatcaatcct gaagaatggg atactatctc ctttgattca gattttatgc
     8521 catttcaaca atcgtaacca atttctcaaa aaagttaaat cttatattta gtactctgca
     8581 aaactcttat ctaatcacgt tgcttatact caatgaaaat caaagagcaa ctttaaacta
     8641 ggaagcgagt cgcagatttc tcaatgcata gctttgagga attgggcaaa aagtctttga
     8701 tatagaaaaa gcatagtatc aggtgtttca acacctgata ctatgctttt tattgtggga
     8761 agatttactt tttttcttct gaaattgagt tgttacccag gctctttcag tttattaagg
     8821 cttgatgact ttaatgtgtt tagatagctt aaaaaggatt gaatcactta gtttagaatc
     8881 tgaaacaata gtatcaagat ttgatacatt ataaaaagta taaaaatcaa acttattgaa
     8941 cttactatga tctgcgagta aatatttttt attagaatta tttaaagcga tgcgttgagc
     9001 ctctccctct tcctcgctaa aagtagctag agctccgttt tgaataccat tacagctaac
     9061 gaaagcttta gaaaattgga gattagagag attttgtagg gtcaatgtgc caacaaaagc
     9121 acctgtaata tcgcgataat ttccacctat caaaatcaaa tctgttaatt ttcgttcgct
     9181 taaaatcaga aaaacaggta gactgttggt tacgacgcgg atattgtcaa taggcaactc
     9241 acgcgcaaaa aactctaatg ttgttcctgg tccaatgaaa atagtttctc tttcttctac
     9301 tagactgcct gcaaaatggg ctatttcttg tttttctgcc gtttggaggg cttgtttttc
     9361 aatatttgat cgctcattag tcaaaaggga gttggttcga agtttttcag ctccaccatg
     9421 cacacgaatc agcaaatctt tatcagctaa ttcctgtaaa tagcgccttg cagtcatatc
     9481 tgaaacggct atttcgtcca taatctgttt aactgttatg gttcctttac tatttactat
     9541 ctctaaaatt ttggctaatt tttcttgttt gagcatatta tcacctcgtt tcctactact
     9601 atcttaccat aaacaaactc atcattcaaa tacaaaaaca acaaaatgaa acaaaaacaa
     9661 aaatatcgaa gtttgttttc aaaactttcg atatttttgt tgggttataa ctttgatgtt
     9721 tctagtttac tttttgatga ttgagagtga tggagaatta gtctaaaccg tagttatagt
     9781 catcgtcttg catggcttca acttcgccaa gaaggtaacc atttccgact tgagagaaga
     9841 agtcatggtt ggaagttcct gttgaaatac cgttcataac gattgggttg acatcttcag
     9901 ctgaatctgg gaaaagtgga tcttgtccca tgttcatgag agctttattg gcattgtagc
     9961 gaaggaaggt tttaacctct tcagtccaac caacaccgtc ataaagactc tctgtgtagc
    10021 cttcttcatt ttcataaaga gtatagagta ggtcgtacat ccattctttg agtttttctt
    10081 gctcttcttc aggcaattca ttgaaaccaa gttggaattt gtaaccaatg taggttccgt
    10141 gaacagactc gtcacgaata atcaatttaa tgatttctgc aacgttggct agtttgttgt
    10201 taccgagata gtagagggga gtgaagaaac cagagtagaa gaggaaggtt tcgaggaaga
    10261 cgctggcaac tttcttttca agtgggctgc cgtttaggta gatttcgttg acaatctcag
    10321 ccttcttttg taggtaagga ttggtattgg tccattcgaa aatttcttca atctcagcct
    10381 tagtattcaa ggtagaaaag attgatgagt aagatttagc gtggacagat tccataaatt
    10441 ggatgttatt gaaaacagct tcctcatgtg gtgtacggat gtctgcgcga agggcttgaa
    10501 ccccagtttc agattgcata gtgtcaagaa gggttaaacc accaaaaact tttccgacca
    10561 agtctttctc tttgttagat agctttctcc agtcatccaa gtcgtttgat aagggaatac
    10621 gtgtatcgag ccaaaattgc tccgtcagtt tttcccaagt tgatttgtcg atgacatctt
    10681 cgatggcatt ccagttaatg gctttgtagt aagtttccat ttaaaatctc tttctgtgtt
    10741 tagtattgcg aactcacaat tatttctact ttaccataat tctataggag tatcgcacaa
    10801 aaagtcggaa gcccgacttt taaaatgtta cataaattat gttatgacat agtagatttg
    10861 attttatcag tgctgcttag ggaaaaataa tgtttctatg ctagaaacta aatcacacag
    10921 ctttcacatt ggttggcgcc gacttctcca ccgtcatctg taaaggtacg gacgtagtag
    10981 atagacttga ttcccttgtt aaaggcatag ttacgaagga tggacaagtc acgtgtcgtt
    11041 tgtttatttt ccctcttcca ttcgtaaagg ccttttggaa tgtcactacg catgaagagg
    11101 gtgagtgaaa gtccttgatc cacgtgttca gtcgcagcag cgtaaacatc gatgacttta
    11161 cgcatatcca tatcgtaggc agaagtgtag taaggaatgg tttctgtaga caagccagca
    11221 gcagggtagt agattttacc aattttcttc tcttggcgtt cttcgatacg ttgcgtaatc
    11281 gggtggatag aagcagaaac gtcgttgata tagctgatag aaccatttgg cgctacagca
    11341 aggcgatttt ggtggtaaag accatcttct tgaaccttgt cgcgaagttc agcccaatca
    11401 gcaacaccag ggataaagac atttttgaag agttctttaa cacggtctga tgttggaaca
    11461 aattcaccag ttacatactt gtcaaagtaa cttccgttag catagtctga tttttcaaag
    11521 ttgtggaagg taataccacg ttcacgcgca atattgtttg actctaccaa ggtccagtag
    11581 ttcataagca taaagtagat gcttgtaaat tcaacagact caggtgaacc atattcaatg
    11641 agttgttggg caaggtagct gtgcagtccc atggcaccga gaccaaaggt gtgggcttgg
    11701 ctatttccat ggtcaatcgt tggtacagct acgatatgtg aactatctgt aacgaaagta
    11761 agggcacgaa ccatagcacg gatagaacga ccaaaatcag gtgaagtcat catgttaacc
    11821 acgttggttg aacccaggtt acatgaaaca tctgttccca tttgaaggaa ttcttgagca
    11881 tcgttgatca agcttggttc ttgaacttga agaatctcag aacacaagtt actcatgata
    11941 atctttccat caacaggatt tgcacggtta gccgtatcga tgttgactac ataaggatag
    12001 ccagactctt gttgcaattt agagatttca gtttccaaat cccgcgcctt gatttttgtc
    12061 ttgcgaatat ttggatttgc gaccaattca tcgtattttt cagtaatgtc gatgtaattg
    12121 aatggcacac cgtattcttt ttctacagag taagggctga agaggtacat ttcttcattt
    12181 ttacgagcca attcgtagaa tttatcaggt actacaacac caagtgatag agtcttgaca
    12241 cgtacttttt catcagcgtt ttctttctta gttgaaagga aagcgatgat atctgggtga
    12301 aagacgttga ggtagacaac accggcacct tgacgttgcc ccaattggtt ggagtaagag
    12361 aagctgtctt caaaaagctt cataacagga acgacacctg aagcagctcc ttcatagcct
    12421 ttgataggtg caccagcttc acgaaggttg ctgagggtaa ttcccacacc accaccaata
    12481 cgtgaaagtt gaagagctga gttgatagaa cgtccgatag agttcatatc atccgtcact
    12541 tggattagga aacaagatac caactctcca cggcgagcac gtccagcatt caagaaggaa
    12601 ggagtagcag gttggtagcg ttggtggatg atttcattgg caatatcgat tgcaacagct
    12661 tcattcccat cagcgaaata aagggcgttg aagaagacac ggtcttccat attttcaaga
    12721 tagtattcac cgtcattagt ctttaaggca tattgattgt aaaatttata agctgccatg
    12781 aatgacttga attggaagtt ttggtctttg ataaattgag ctaattcttc caagaactct
    12841 ggacggtatt tcttgataaa ggctgtttcg atgtagttgt gttcaatgag gtaattgatt
    12901 ttgtctttga ttgaatcaaa aaccatagtg tttggaacta cattttcttt aaagaaagca
    12961 tccaaggctt ccttgtcttt atgaagcatg atttgtccat taacaggacg gttaatttcg
    13021 ttattaagac ggaagtaagt cacgtcttca agatgtttta atcccataaa atttccctta
    13081 tctaattaca aaagaaaggc ttctaagtta gccctaaaag cagtttcttc tggatgatgt
    13141 actaagatta tgctaattgt ttcagttttc ctggttggaa acctgaaaag acttcagttg
    13201 gtgtttggat aacaggagct gcgctaaaac cgagctcttt aacttgatcg acgtactcag
    13261 gttgctcatc aagattgatt tcacgataag agacattatt actgtccaag aaacgcttgg
    13321 tcattttaca ttggacacaa ttgtttttag aataaacggt taccattgtg taactcctct
    13381 tcaaaattta atactatctt agtatatcag aaaataaaat tttgtcaatg atttgaacta
    13441 aatatagtgg tgttcttttg ttgtttttat atataaacac aatatatagt gtttgtattg
    13501 tgaaatagca atgattatcc tataaattgt ttttaaagaa actatatcct gtgttttgtt
    13561 atctaggata gaagattttc agcaagttat ctgaaaggaa attgaaggaa aatccagaaa
    13621 atgcttgaaa aaaatcctag aagatggtat aatactaaat tgtaagggtt atcacatata
    13681 actcaaaaaa agaaagaaca aaaggagagt caaactatgg cttctaaaga tttccacgta
    13741 gtggcagaaa caggtattca cgcacgtcca gcaacattgt tggtacaaac tgctagcaaa
    13801 tttgcttcag atatcactct tgagtacaaa ggtaaatcag ttaaccttaa atcaattatg
    13861 ggtgttatga gtcttggtgt tggccaaggt gctgacgtaa ctatctcagc tgaaggtgca
    13921 gatgcagatg acgctatcgc tgcaatctca gaaacaatgg aaaaagaagg attggcataa
    13981 gggaaatgac agaaatgctt aaaggaatcg cagcatctga cggtgttgca gttgcaaaag
    14041 catatctact cgttcagccg gatttgtcat ttgagactat tacagtcgaa gatacaaacg
    14101 cagaagaagc tcgccttgat gccgctctac aggcatcaca agacgagctt tctgttattc
    14161 gcgagaaagc agtaggtacg ctcggtgaag aagcagctca agtttttgat gctcacttaa
    14221 tggttcttgc tgacccagaa atgatcagcc aaatcaagga aactatccgt gcgaagaaag
    14281 tgaatgcaga agcaggtctg aaagaagtta cagatatgtt tatcactatc tttgaaggca
    14341 tggaagacaa cccatacatg caagaacgcg cagcggatat ccgcgacgtg acaaaacgtg
    14401 tattggcaaa ccttcttggt aaaaaattgc caaacccagc ttctattaat gaagaagtga
    14461 ttgtgattgc gcatgacttg acaccatctg atacagctca attggacaaa aactttgtaa
    14521 aagcttttgt aaccaacatt ggtggacgta caagccactc agctatcatg gcacgtacac
    14581 ttgaaattgc tgctgtatta ggtacaaata acatcactga aatcgttaaa gacggtgaca
    14641 tccttgctgt taacgggatc actggagaag tgattatcaa cccaacagat gaacaagcgg
    14701 cagaatttaa agcagctggt gaagcctatg cgaaacaaaa agctgaatgg gcacttttga
    14761 aagatgctca aacagtgact gctgacggta aacacttcga gttggctgcc aatattggta
    14821 ctccaaaaga cgttgaaggt gttaacaaca acggtgcaga agctgttgga ctttaccgta
    14881 cagagttctt gtacatggat tctcaagact tcccaactga agatgagcag tatgaagcat
    14941 acaaggctgt tcttgaagga atgaacggta aacctgttgt cgttcgtaca atggatatcg
    15001 gtggagataa ggaacttcct tacttcgata tgcctcacga aatgaaccca ttccttggat
    15061 tccgtgctct tcgtatctct atctctgaga ctggagatgc tatgttccgc acacaaatcc
    15121 gtgctcttct tcgtgcgtct gttcacggtc aattgcgtat catgttccca atggttgcgc
    15181 tcttgaaaga attccgtgca gcgaaagcag tctttgatga agaaaaagca aaccttcttg
    15241 ctgaaggtgt tgcagttgcg gataacatcc aagttggtat catgatcgag attcctgcag
    15301 cggctatgct tgcagaccaa tttgctaaag aagttgactt cttctcaatt ggtacaaacg
    15361 acttgatcca atatacaatg gcagcagacc gtatgaacga acaagtttca tacctttacc
    15421 aaccatacaa cccatcaatc ctacgcttga ttaacaatgt gatcaaagca gctcacgctg
    15481 aaggtaaatg ggctggtatg tgtggtgaga tggctggtga ccaacaagct gttccacttc
    15541 ttgtcggaat gggcttggat gagttctcta tgtcagcaac atctgtactt cgtacacgca
    15601 gcttgatgaa gaaactcgac acagctaaga tggaagagta cgcaaaccgt gcccttacag
    15661 aatgctcaac aatggaagaa gttcttgaac ttcaaaaaga atacgttaat tttgattaat
    15721 cgaaaagtcc ctgcaactca gttacaggga ctttttttga tattttaaaa agaattttca
    15781 agaaaatctt tcttataaaa agtccaacct tgaaaaagta gtggtcagaa caaaaaatac
    15841 ttaaatggtt cataaaattc ttgacaagtt ggagatttag gagtaaacta ttaaccagtt
    15901 aagtaataga gaggagtttc tgcaatttag aaatgaattg caactagaaa tatcaaatag
    15961 aaagagagtt tcgatgaaaa ttaataagaa ataccttgtt ggttctgcgg cagctttgat
    16021 tttaagtgtt tgttcttacg agttgggact gtatcaagct agaacggtta aggaaaataa
    16081 tcgtgtttcc tatatagatg gaaaacaagc gacgcaaaaa acggagaatt tgactcctga
    16141 tgaggttagc aagcgtgaag gaatcaatgc tgagcaaatc gtcatcaaga taacagacca
    16201 aggctatgtc acttcacatg gcgaccacta tcattattac aatggtaagg ttccttatga
    16261 tgcgattttc agtgaagaat tactcatgaa agatccaaac tataagctaa aagatgagga
    16321 tattgttaat gaggtcaagg gtggatatgt tatcaaggta gatggaaaat actatgttta
    16381 ccttaaggat gctgcccacg cggataacgt ccgtacaaaa gaggaaatca atcgacaaaa
    16441 acaagaacat agtcaacatc gtgaaggtgg gactccaaga aacgatggtg ctgttgcctt
    16501 ggcacgttcg caaggacgct atactacaga tgatggttat atctttaatg cttctgatat
    16561 catagaggat actggtgatg cttatatcgt tcctcatgga gatcattacc attacattcc
    16621 taagaatgag ttatcagcta gcgagttggc tgctgcagaa gccttcctat ctggtcgggg
    16681 aaatctgtca aattcaagaa cctatcgccg acaaaatagc gataacactt caagaacaaa
    16741 ctgggtacct tctgtaagca atccaggaac tacaaatact aacacaagca acaacagcaa
    16801 cactaacagt caagcaagtc aaagtaatga cattgatagt ctcttgaaac agctctacaa
    16861 actgcctttg agtcaacgac atgtagaatc tgatggcctt gttttcgacc cagcgcaaat
    16921 cacaagtcga acagctagag gtgttgcagt gccacacgga gatcattacc acttcatccc
    16981 ttactctcaa atgtctgaat tggaagaacg aatcgctcgt attattcccc ttcgttatcg
    17041 ttcaaaccat tgggtaccag attcaaggcc agaacaacca agtccacaac cgactccgga
    17101 acctagtcca ggcccgcaac ctgcaccaaa tcttaaaata gactcaaatt cttctttggt
    17161 tagtcagctg gtacgaaaag ttggggaagg atatgtattc gaagaaaagg gcatctctcg
    17221 ttatgtcttt gcgaaagatt taccatctga aactgttaaa aatcttgaaa gtaagttatc
    17281 aaaacaagag agtgtttcac acactttaac tgctaaaaaa gaaaatgttg ctcctcgtga
    17341 ccaagaattt tatgataaag catataatct gttaactgag gctcataaag ccttgtttga
    17401 aaataagggt cgtaattctg atttccaagc cttagacaaa ttattagaac gcttgaatga
    17461 tgaatcgact aataaagaaa aattggtaga tgatttattg gcattcctag caccaattac
    17521 ccatccagag cgacttggca agccaaattc tcaaattgag tatactgaag acgaagttcg
    17581 tattgctcaa ttagctgata agtatacaac gtcagatggt tacatttttg atgaacatga
    17641 tataatcagt gatgaaggag atgcatatgt aacgcctcat atgggccata gtcactggat
    17701 tggaaaagat agcctttctg ataaggaaaa agttgcagct caagcctata ctaaagaaaa
    17761 aggtatccta cctccatctc cagacgcaga tgttaaagca aatccaactg gagatagtgc
    17821 agcagctatt tacaatcgtg tgaaagggga aaaacgaatt ccactcgttc gacttccata
    17881 tatggttgag catacagttg aggttaaaaa cggtaatttg attattcctc ataaggatca
    17941 ttaccataat attaaatttg cttggtttga tgatcacaca tacaaagctc caaatggcta
    18001 taccttggaa gatttgtttg cgacgattaa gtactacgta gaacaccctg acgaacgtcc
    18061 acattctaat gatggatggg gcaatgccag tgagcatgtg ttaggcaaga aagaccacag
    18121 tgaagatcca aataagaact tcaaagcgga tgaagagcca gtagaggaaa cacctgctga
    18181 gccagaagtc cctcaagtag agactgaaaa agtagaagcc caactcaaag aagcagaagt
    18241 tttgcttgcg aaagtaacgg attctagtct gaaagccaat gcaacagaaa ctctagctgg
    18301 tttacgaaat aatttgactc ttcaaattat ggataacaat agtatcatgg cagaagcaga
    18361 aaaattactt gcgttgttaa aaggaagtaa tccttcatct gtaagtaagg aaaaaataaa
    18421 ctaatgaaaa atgaaagtct cgataaagag gctttcattt ttattatgta tatatgtaaa
    18481 attcttgaca agcaatatta aaaagagtaa actattaact agttaattaa ccggtttatt
    18541 actttatagt gaatcaaata tacttaagaa aagaggaaag aatgaaaatc aataaaaaat
    18601 atctagctgg gtcagtagct acacttgttt taagtgtctg tgcttatgaa ctaggtttgc
    18661 atcaagctca aactgtaaaa gaaaataatc gtgtttccta tatagatgga aaacaagcga
    18721 cgcaaaaaac ggagaatttg actcctgatg aggttagcaa gcgtgaagga atcaatgccg
    18781 aacaaatcgt catcaagata acagaccaag gctatgtcac ttcacatggg gaccactatc
    18841 attattacaa tggtaaggtt ccttatgacg ctatcatcag tgaagaattg ctgatgaagg
    18901 atccaaacta ccagctaaag gacgaggata ttatcagtga aatcaagggt ggttatgtga
    18961 ttaaggtaga tggaaaatac tatgtttacc ttaaggatgc agctcatgcg gataatgtcc
    19021 gtacaaaaga agaaatcaat cggcaaaaac aagaacatag tcagcatcgt gaaggaggga
    19081 cttcaacaaa cgatggtgcg gtagcctttg cacgttcaca aggacgctat actacagatg
    19141 atggttatat ctttaatgct tctgatatca ttgaggacac gggtgatgct tatatcgttc
    19201 ctcacggcga ccattaccat tacattccta agaatgagtt atcagctagc gagttagctg
    19261 ctgcagaagc cttcctatct ggtcggggaa atctgtcaaa ttcaagaacc tatcgccgac
    19321 aaaatagcga taacacttca agaacaaact ggctaccttc tgtaagcaat ccaggaacta
    19381 caaatactaa cacaagcaac aacagcaaca ctaacagtca agcaagtcaa agtaatgaca
    19441 ttgatagtct cttgaaacag ctctacaaac tgcctttgag tcaacgccat gtagaatctg
    19501 atggccttgt tttcgaccca gcgcaaatca caagtcgaac cgccagaggt gtagctgtcc
    19561 ctcatggtaa ccattaccac tttatccctt atgaacaaat gtctgaattg gaaaaacgaa
    19621 ttgctcgtat tattcccctt cgttatcgtt caaaccattg ggtaccagat tcaagaccag
    19681 aacaaccaag tccacaatcg actccggaac ctagtccaag tctgcaacct gcaccaaatc
    19741 ctcaaccagc tccaagcaat ccaattgatg agaaattggt caaagaagct gttcgaaaag
    19801 taggcgatgg ttatgtcttt gaggagaatg gagtttctcg ttatatccca gccaaggatc
    19861 tttcagcaga aacagcagca ggcattgata gcaaactggc caagcaggaa agtttatcgc
    19921 ataagctagg agctaagaaa actgacctcc catctagtga tagagaattt tacaataaga
    19981 cttatgactt actagcaaga attcaccaag atttacttga taataaaggt cgacaagttg
    20041 attttgaggc tttggataac ctgttggaac gactcaagga tgtctcaagt gataaagtca
    20101 agttagtgga tgatattctt gccttcttag ctccgattcg tcatccagaa cgtttagg
//
LOCUS       DAVBEM010000042        19766 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVBEM010000042 DAVBEM010000000
VERSION     DAVBEM010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19766
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.042"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(481..1206)
                     /locus_tag="VQ548_001545"
     CDS             complement(481..1206)
                     /locus_tag="VQ548_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654374.1"
                     /translation="MKLLKNELIKSKIFLFIIVDICIQILVILAIKTYILDISAPYSE
                     LDYNKYWYVLHALIYMPMIFPIQILYQNLREALIEDNNNGWNIMVINTNNLVKIIYIK
                     VTINIVRCFICYFVYTIFSLIQLGGMGTDMLLTNIIFPNIIFPNIMSFLLFLPIAIFM
                     QICCIRFDSILAKALPNILLILIVLITFQSDWNIFIPATYYYTEIQSTTNLGIKLLVC
                     IWIMGFEFSLLPKLIKLKEQNLV"
     gene            complement(1219..1956)
                     /locus_tag="VQ548_001546"
     CDS             complement(1219..1956)
                     /locus_tag="VQ548_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2654375.1"
                     /translation="MIKLEFLKQKKSILWFVLIFPIILNALLYIDLTFRYRGYLLVHQ
                     NELALSNWQLIFKEQTIFYFSELFYLVLSLIIYEVFAVEFKNDAWLTVISLPFRNKYT
                     INSKLLITVVYTFTFWLSDYISLYVIGKAIDNSLEIGLIFFLKTFTIQLISSLMIMLL
                     YFLTLVLIRKISGIIPIGIIMMILTISIYYNDYNFKIYLPFTYLSHAFRVTESQFYMI
                     LLSNIIIIVLFYILIRKLNERSFEMKL"
     gene            complement(1949..2677)
                     /locus_tag="VQ548_001547"
     CDS             complement(1949..2677)
                     /locus_tag="VQ548_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2654376.1"
                     /translation="MAIVEIINLTKSFKDIEVIHNTSFYLNKGKVYGFVGPNGAGKTT
                     IIKMILGILKPDSGKITIFNQTVEQNSKNILSRIGLVLGPSFYGHLDAYKNLKLIANM
                     KGLSLDTERLNEYLSMVGLKDVKKKKVKNFSMGMKQRLSIAASLLGSPEILIWDEPIN
                     GLDPQGVIEIRSLIRFLQEKKGITFLISSHILSELDKVISDIIIINYGKVEFFGSCHY
                     LLQKYNCRNLEEAYLACLAGGEYD"
     gene            complement(2711..2881)
                     /locus_tag="VQ548_001548"
     CDS             complement(2711..2881)
                     /locus_tag="VQ548_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654377.1"
                     /translation="MKKVNEYVISTAASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2924..5017)
                     /locus_tag="VQ548_001549"
                     /pseudo
     CDS             complement(2924..5017)
                     /locus_tag="VQ548_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397758.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
     gene            complement(5010..5558)
                     /locus_tag="VQ548_001550"
                     /pseudo
     CDS             complement(5010..5558)
                     /locus_tag="VQ548_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000059560.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5639..5701)
                     /locus_tag="VQ548_001551"
     CDS             complement(5639..5701)
                     /locus_tag="VQ548_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HET2654378.1"
                     /translation="MKKISKFLPILVLVMDIIII"
     gene            complement(5870..6858)
                     /locus_tag="VQ548_001552"
                     /pseudo
     CDS             complement(5870..6858)
                     /locus_tag="VQ548_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050775.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(6807..7934)
                     /locus_tag="VQ548_001553"
                     /pseudo
     CDS             complement(6807..7934)
                     /locus_tag="VQ548_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423473.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
     gene            complement(8097..8981)
                     /locus_tag="VQ548_001554"
     CDS             complement(8097..8981)
                     /locus_tag="VQ548_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HET2654379.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(9093..9947)
                     /locus_tag="VQ548_001555"
     CDS             complement(9093..9947)
                     /locus_tag="VQ548_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HET2654380.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNLTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCNIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(10005..10763)
                     /locus_tag="VQ548_001556"
     CDS             complement(10005..10763)
                     /locus_tag="VQ548_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET2654381.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYALS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            complement(10825..11013)
                     /locus_tag="VQ548_001557"
     CDS             complement(10825..11013)
                     /locus_tag="VQ548_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HET2654382.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(11335..11901)
                     /locus_tag="VQ548_001558"
     CDS             complement(11335..11901)
                     /locus_tag="VQ548_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654383.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKTYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(12169..13848)
                     /locus_tag="VQ548_001559"
     CDS             complement(12169..13848)
                     /locus_tag="VQ548_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HET2654384.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCNHRQMIRGHKCTFSKQIGEELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKVDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            complement(13940..14101)
                     /locus_tag="VQ548_001560"
     CDS             complement(13940..14101)
                     /locus_tag="VQ548_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654385.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(14785..15099)
                     /locus_tag="VQ548_001561"
     CDS             complement(14785..15099)
                     /locus_tag="VQ548_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654386.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            complement(15065..15454)
                     /locus_tag="VQ548_001562"
     CDS             complement(15065..15454)
                     /locus_tag="VQ548_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2654387.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            complement(15842..16636)
                     /locus_tag="VQ548_001563"
     CDS             complement(15842..16636)
                     /locus_tag="VQ548_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2654388.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            complement(16636..17643)
                     /locus_tag="VQ548_001564"
     CDS             complement(16636..17643)
                     /locus_tag="VQ548_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2654389.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(17643..18650)
                     /locus_tag="VQ548_001565"
     CDS             complement(17643..18650)
                     /locus_tag="VQ548_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2654390.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLATFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(18640..19665)
                     /locus_tag="VQ548_001566"
     CDS             complement(18640..19665)
                     /locus_tag="VQ548_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HET2654391.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
BASE COUNT         6376 a         3632 c         2619 g         7139 t
ORIGIN      
        1 tggacatttt gaactaaaat taatttatta aacatatctc ataagcatat ctattatagg
       61 tgagacaata ttaagaaaga cggttaaaaa acaacctgac tccactggaa ttcaggaatc
      121 aggtcgctta agattttata ttattttact gtctacttga cagggagctg ttcaccaatg
      181 ggaatctata gctttttttg tgactgagaa ctattttatc tcagacttct tcaacacacc
      241 ttattattgg gcacttacgg aaggttaatg aattatttaa aataaaagta aagagaagca
      301 aacagacact ctatagctgt tagacgcttt ttagagtaat aacaatttga taaagtgaat
      361 acaacttgct taattaagcg taagaaacca gaatcataaa atcaattact ttgaagtcat
      421 gactcacgtt gtattgtttc attgttaatc gtattcaatt atttaatttt cgagcaacat
      481 ttaaactaga ttttgttctt tcaattttat tagttttgga agaagggaaa attcaaatcc
      541 cataatccag atacaaacta ataatttaat acctaagttt gtagttgact gaatttctgt
      601 ataataataa gttgcaggta taaatatatt ccaatcactc tgaaacgtga ttaaaacaat
      661 aagtatcagc aaaatattag gtaaggcctt tgctaaaatg gaatcaaatc ttatacagca
      721 aatttgcata aagatagcta taggtaaaaa taacagaaat gacattatat tgggaaatat
      781 tatattggga aatattatat tggttaataa catatcagtt cccataccac ctaattgaat
      841 taaagaaaaa attgtataaa caaaataaca aataaaacat ctcacgatat ttatcgttac
      901 ttttatatag atgattttca cgagattatt agtgttaatc accatgatat tccaaccatt
      961 attattatct tcaatcaatg cctctcttag attttgatac aaaatttgta taggaaaaat
     1021 cattggcata tatattaaag cgtgtaaaac ataccaatac ttattataat caagctctga
     1081 gtatggtgcc gaaatatcta aaatatatgt ttttatagct agaatgacta gaatctgaat
     1141 acagatgtca acaataataa ataaaaatat tttactctta atcaattcat ttttaagtaa
     1201 cttcattttt attacctatt aaagtttcat ctcaaaactt ctttcgttca atttacgaat
     1261 taatatataa aaaagtacga tgattattat attagatagt aaaatcatat aaaattgact
     1321 ttcagtcact ctaaaagcat gagaaagata agtaaatggt aagtaaatct taaaattata
     1381 atcgttgtag tatatgctaa ttgttaaaat catcattata ataccaattg gtattattcc
     1441 agaaattttc cttataagta ctaaagttag aaaatataat aacattatca tcaacgagga
     1501 aattaattga atggtaaatg tttttaaaaa gaaaatcaaa ccaatctcta aactgttatc
     1561 aatagccttc ccaataacgt ataagctaat ataatcagac aaccaaaaag taaatgtgta
     1621 aaccactgta atgagtaatt tagaatttat tgtgtacttg tttctaaatg gcaatgaaat
     1681 tacggttaac catgcatcat ttttaaattc tactgcaaac acttcgtaaa ttattaaaga
     1741 tagaactaaa taaaatagtt cagaaaaata aaatattgtt tgttctttaa aaattaactg
     1801 ccaattagat aaagcaagtt cattttgatg caccaataaa taacctcgat acctaaaagt
     1861 taagtctata tataacaaag cattcagaat tattggaaaa ataagaacaa accataagat
     1921 gctttttttc tgctttagaa actctaattt aatcatattc acctccagct aaacaagcta
     1981 agtaggcttc ttccagattt cgacaattat acttttgtaa aaggtagtgg caagaaccaa
     2041 aaaattcaac tttcccataa tttataatta taatatcaga tatcacttta tccagttcac
     2101 taagaatatg acttgatatt aaaaatgtaa tacctttttt ctcctgtaga aaacggatta
     2161 aacttctaat ttcaattaca ccctgtggat caagtccatt gattggttca tcccaaatta
     2221 atatttctgg actacctaac aatgatgcag ctatacttag acgttgtttc atgcccattg
     2281 aaaaattttt cacttttttc tttttaacat cttttaatcc taccattgat agatattcat
     2341 taagtctttc agtatctaaa ctaagccctt tcatatttgc tattaacttc aaatttttat
     2401 aagcatcaag atgaccataa aatgaaggtc ccaaaactaa tcctatccta gataatatat
     2461 ttttggaatt ctgttctacg gtttgattaa aaatagttat tttcccagaa tctggtttta
     2521 aaatccctag aatcattttg ataattgtag tttttccagc cccatttggt ccaacaaaac
     2581 catatacttt tcccttattt aaataaaatg aagtgttatg aataacttca atatctttaa
     2641 agctttttgt tagatttata atttcaacta tagccatctc tactccttag tttacagcaa
     2701 aaaattatgc ttaattctta ttgtttttgt aaacaatcag cgaacccaat actattccat
     2761 tcaacaaacc taaagaaata ccatattcaa ctggaaaatc taaaaaaatt gcaaatacta
     2821 ttccaatcat cacccctagt gaggctgctg ttgaaattac atattcattt actttcttca
     2881 ttttctttac acctcatttc ctttttgtat ataagctgta gtactatcca ccaagatcca
     2941 ttaagtactt atgatttcct gactcaacaa tcttaccacc tttcattaca aaaataatat
     3001 ccgcatcctt aatcgttgac aatctatgag ctataattat ttgagtacaa tcctgacttt
     3061 gtatatactt tgttattctt tcctcattaa tagtgtctaa tgcactagtt gcttcatcta
     3121 aaattacaat actaggatta tttattaatg cacgtgccag tgctatccgt tgcctttgcc
     3181 cacctgaaat atttgacccc atctctgaga tgatagtatt aaatttcatc ggcatagcca
     3241 tgatttcatc atagatttga actgctttac aaacttcctc tatcttttgt gaagtaactt
     3301 cgttctttaa agttatatta tcaagaatac ttcggttcaa taaaaatgaa tcctgtggaa
     3361 ctactcctaa attttgactt aatatttttt tatctatttg attaatattt acaccatcaa
     3421 ataaaatttt tcctgtatca atcttatata atcctgatag tatttttgat aacgtacttt
     3481 ttcctgaccc cgattgaccg actagtgcaa ttctctgtcc tggctcaata gtcaaattta
     3541 aattttctat tacaggagct gagtctttgg aataagagaa agataggtcc ttaatatcta
     3601 ttctaccttc taaagaacac tttttaagac cattttcaac attctcttca ttttcaagcc
     3661 agatatcatt tactctattt aagtatcctg ctgccaaaat atactacgta taagcattaa
     3721 atattgagat ttctgaacta aataaaattg atgccatcgt ttgaaatgcg acaacctcac
     3781 ccaataaaat ttttccattt aaaacattat caagtccaaa aatcaatata attataggag
     3841 cgaacaattg aaatacatta gtagctgaat tgtataaaat atgcacaata cttcgttttt
     3901 tatactttgt caatacgttt tttaaatact tagaccagtt ttcatatatt tcatcttcta
     3961 atcccgatat ttttattgaa gaaatagtat ttaatgcttc tgtttctact gagtaaatca
     4021 atgattgttc ttgtaattct ctattaaccg tatcatacat tatttttcta gtactaaaca
     4081 gaaacaaaaa attgattaaa ctcaatataa gagctataat tgataatgtt tttgaactaa
     4141 gaaacatata tattacaaca cttagaatag tcccgatatc tactactccc ccaacaactt
     4201 ggttagtaaa tagctcccta aaaccactaa gactagaaat tctgtataaa atatctcctt
     4261 ttgccctgag ttcaaaaaaa ctatatggta gtttaagcaa atgcttaaat gtaaaacttt
     4321 caatatctct actaaaaaat atattagaaa atagaattcc catactccta gccaagatag
     4381 aaataaggta caaacaaagt agagaaaata aaattaaaaa cgaggtttga aaagaaaatg
     4441 tattccctaa tgcagaatta ataaactttg aagtcattac tggtacggaa agtattatta
     4501 agtaacttat tattgaaaat agtaacgtca aaatcaatcg accttttacc tttgaaaaac
     4561 tagagaatac tcttatccat ggagaaggaa actgcgactt caaagattga taattttcgt
     4621 taggaaatga tagcagtact atattactaa aatgttttga aaactcctta aactcataat
     4681 ttatatatcc tttagaagga tccattatat agaccttatt cttttttact ttgtaaataa
     4741 ctacataatg ttgattatcc cagaatgcta ttaatggtaa cggaagttca ctaattttat
     4801 ttacatcttt aacttgatat gagccagtat caaaatttcg tttattcaat aactgtttca
     4861 agtcacctat actataacca tctctccctt tttctatatc acgtcttaaa tctagtaatg
     4921 tctctttgct tttatagaaa tgtagtatgg acaagcagca acataaacca cattctattt
     4981 gagacatttg ctcaatatta ggtacttttc tagtcatcat gtcctcttaa ctccagtaat
     5041 aaaacattaa gtaatctatc atcttgtttt cgagatattt catagacaac tccagatact
     5101 cctagcataa aagaaaatgt attcatagta ttcaaatccg tacttaattc tggtttgata
     5161 acctgagaaa cgacattatc aaaataaaaa tctatagatt cttttattaa taggttttct
     5221 tcatctttca atattgcatc aagacaactg atagtaccta cagaaccgtg acataaattc
     5281 aattctctta ttttttctac attagttaat acattttcaa ttattgataa atcattattc
     5341 ccaatattag ttttatcgaa aatttctttt ctagctaata aaatgcccgg agctccataa
     5401 caccaaaaat taggaaagga atcattatga tttcttcata tgtctttcca attttttaat
     5461 atattattga aacatttatc ttctttatat agtaattcct ctatacattt taatatatct
     5521 gtactaggat taatttcata ataatatgat aattacattg ctactccaga ataatcgtgt
     5581 gctaaacctg ttactgttat attatctaat tgtgaaatac aataattaat acactttttt
     5641 aaatgatgat aatatccatc accaaaacca aaatcggtaa aaattttgaa attttcttca
     5701 tacttggact tcctttccgt ttttatttat tgtacaataa ataaaaacgg atttaatttt
     5761 tgttgggaaa atgggaaatt atgaaatcaa aacttggcat cacacttaga aaagttcgta
     5821 aaggaaaaca aattagtcta tgctctgtag cagatgaaca tctttcaaaa tcacaaatat
     5881 ctcgttttga acgtggggag tcagagatat cttgtattcg actaatcaat attttagaca
     5941 aattacatat tactttgtag gggagttttt ggctatcgtt gctcaattgt ctgattaagg
     6001 tcctaccctt gatgaaacaa ttattatcca tgttttcttt attatagaca aagtaagaag
     6061 acgtttctcg aatgtagact ttatattttt tatgattttc ttcttccata atatccaatt
     6121 gatagttggg aatgaaaata agaccgctct gtttgacacc gaaagacacc ttgatataga
     6181 cgcccttatc aactagcttc tctatttggt tctctgcaag ttccacttca aattcacgaa
     6241 cggtatctca tttttcctta aatgtcttaa aggcttcctc aatctcttca gtggatactt
     6301 tatccttatc tcgttcttct tggaaagcat ggtactgttc ctgtaaattc tctaatcctt
     6361 ctgaagcaac gacttcctta tttttaaaat aatcttgaaa aaatttgaca tcatataatt
     6421 tcttatcact tattttttga tgacccaaac ttatcttttg attattttct tccaggataa
     6481 aagttacatt ttttgtttta agtcaatggt tagattcaat tcttttgctt ttgttattaa
     6541 atcttctaaa gaattgacac ggtttaacaa aaattctaaa cgactttcaa tctcttgctt
     6601 agcaaaatgc gttctaaaaa attcttcatc atatagatct cgtttgctga gttggcgccc
     6661 tcgaattggt tttatcatcg ttctatctgt catcaaaaaa cggctatgct tttgactaaa
     6721 atcaatctga acatgcaact gctttgcttt ctctaaaaaa tcatcaaacg atttagattg
     6781 ctgaagcaaa aaataaagac gttgtttcaa ttcaaattta tgactagatt ccttatattt
     6841 tttataatct cgaaaagatc aggattttta gctaaaactg ccttacgaaa atccttccag
     6901 aactgatggt caatctcatt agccacatcc aaacgccaag catcgatatt aaactcttca
     6961 atccaataag tcgcaacctt taaaagataa ttcttgacct ctggattggc tgtatttagc
     7021 ttaggcatat agtcctcgaa accaaaaaca tgatagggta agtctctctt attaactagc
     7081 ttttcagttg tcaatgggaa ttgttgaata tggaaccaat ccttataagc agactgttca
     7141 ccatttttga cgacattttt tcattgaaga gattgcgaac caatatgatt aaataccgca
     7201 tccagcatga ctttcatgcc acgatgatgc gcttgatcca ccagttcccg aaaggtctcc
     7261 ttgtctccaa aataacggtc aatttcaaag taatctgtcg tattgtactt gtgattactt
     7321 gtagattcaa agatgggaca aagatatagt ccagtaatac ccaagtcttg caagtaattc
     7381 atatgatcaa taatcccctg taaatcacca ccaaagaaat catcgctctt aggtgtgaca
     7441 gatgaatccc agtctaaagt cccttctggg tttaatagag cattgccatt ggcaaatctt
     7501 tcaggaaata tctgatacca taccgtattt gaaacccagt caggaacctt gcaggcatca
     7561 atctcatgaa gataaggcaa cttaaatcca ttcccaattg catgaagatt ttctagagaa
     7621 ttttccacac accctttatc gccatacaaa atattttgac cttctgtatc tctgagctca
     7681 aagagatact ggatacgtgc aaagtcaact gacacttcaa cctgccaatg gtcaaataag
     7741 gtaccagaag ttatcttgac catttctttt gtatcctgat aaaactcttc cataaagata
     7801 aaagggtccc catagtgcaa gttgatgctt tcaatgtccc ctttcttagt tcgaattcga
     7861 atatggagtt tcttatcctt ataaagatag gcatactccg actcaggcct atggtaaata
     7921 gcactcaatt ccatcaattt gtctcctaaa gtattcattc aaattttacg caaacgtttt
     7981 caaactcaat aaatccagta tactattttt gtaaactatt tgcaaggaat gtccgttgtt
     8041 aaaggaacta tcttttaaag tatacaaaaa gccttaaaaa aggctttctc tatatactaa
     8101 tcctctttcg gttttgaaaa tacttctact cgctgagcta ggactttgat ttctacaggt
     8161 aggttatctg atttatctcc gtcaacatct gactccaatt cactatctga agagatttta
     8221 atattacgcg ctttgatata ctcgatatta tcatttgcga caacatcccc ttttaataaa
     8281 tcaggaatga cggataattt ggagaatata gaggcatctt tcagaatcaa aatgttggca
     8341 tagccgtcct tgttttcttc aaagattttc ttatcagcga agtaatttgt caaaaggacc
     8401 aaaacatggc tagcttcacc aacataattt ccattttctg tctcaacctt aatgttaaag
     8461 acctgatctg tcatgacaga cttcatggta tttacagcat aggttaaaat accgaatttt
     8521 gttttgtcct ctatttcaac attgtgaatc gcctcaggca gagaaccgat actaaagata
     8581 taaccaaaat agttgtcatt tgctttaccg atatcaatct tattggttaa atcaaaatcc
     8641 agttcgtcaa ttgcgccatc gatgtcttga ttgatttcca aaagttttgt aatgaggtta
     8701 cccgtaccgc ctgggataat ccctaactta ggaatgtagt ctctctcatc aatacctgaa
     8761 atgacttcat tgacagttcc atctccacca aacacaacca ctgcatcata ctgctcacga
     8821 gaagcttctt cagcaaaatg tgttgcatcc agcgcttttt cggtaatttt ggtttcaaca
     8881 tattcaaagt attcttttgc tttattctcc agcttttctt tgtaatccaa agccttctcg
     8941 ccaccagaag tagggttgat aattaccatt gcttttttca ttgattttat ccttaatttt
     9001 aaacagaaat gtttacattt cgtcgtatgc aagtaaatgt aatcctatta tacaatgaaa
     9061 atacagaaaa gagaaatctg acgtactgga gattaatacg cttttattct attttcccat
     9121 cgcctaacta catcctttaa gggttcatcc aagtaagaat aggccttatc cttgatccaa
     9181 tcaggaatac cgtaagctgc ctctgctatg ttacaagtga ttgctgcgag agtatcactg
     9241 tcgccaccaa gtgagatggc atttcttatc gcatcttcga agtctctact ttcaagaaag
     9301 gcgataatgg cttgagggac agtttcctga catgtttcgt taaaacgata gttaggacgg
     9361 atttcatcta aagtttgaga tagattgtaa tcgtattctt tttctatata atccttaatt
     9421 cgtcttttac actctgtaag attgtcgtta attgattgct cgtactctct acaataacca
     9481 ccaaagtaaa aacgacatag aaagatagca tcagctgtag ccatagcgcc tttgacacct
     9541 tctggatgat tatgagttac ctctgcagaa agactcgtaa gtcctctaga tgatggccat
     9601 ataccagttt tcgcataaaa accacagtcc atgatccaag cacatggaga aatacgcata
     9661 gctgatccat tcccaaagct attataaggc tcacggttat cgctgtttag ccatgcatta
     9721 aaccgagcac cgtaatcagc attcggatac attctgccat atttcttcat cgcgtcaatg
     9781 aaatcgtctt tttgtccacc attcataatt gcttctgcaa cagcacaggt cataaccgtg
     9841 tcatctgtaa aaaagcagtc cttccgaaat aaaggaaagt cctttgtttt gatattgttc
     9901 cattcgtaaa cagaaccgac aatatctcca ataattgctc caagcatcag attcctcctt
     9961 gttcattttg atgcttttta tattggttat ataccatatt tattttagaa aacaacatcc
    10021 tgttggattt taaaaatttc atttttttca aaatagggtt ttaccatttc tttccaccta
    10081 gctctatgaa aattgattga ttttaaagga gatagggcat aatttcccaa tgcataacca
    10141 tcatttactt caacaacaag tgttctgcca tcgcgagtaa caccgatatc tagtccataa
    10201 gctattggcg catctttcca acatgatatc gcttcatcaa ttacacttgc atcaaattgt
    10261 gcatgataat cacctgtata gggtcgaaca tctaatacgc gaccatctaa cacaaaacaa
    10321 cgccattcag ctatgaattc tacaacctca ctaatccata taggatagtc gaaaggtaga
    10381 ccaataccta ttaaatcatg ggttccatta acaactcttc cagtaaagac ttttgaacca
    10441 gctttaggct taataaattt tccccaatta tcaggtatat tcacaatctc tcctaaaata
    10501 ccagcataaa tctttcgacc ataaaactct ttaagctcaa taggatagtc ataaaccgga
    10561 acgtttaagc ccatcatttt tagtaatgct ctagtctcca ttatataatc tacaactata
    10621 tcttcacttg ttaactcttt tatttcagaa aaagattgat ataaaataac ttcttctcct
    10681 tgtaagtagg cacctacttg agcattgtat ttattaattg aaacctcact tggtaattta
    10741 ctttgtctaa tataaacaac catttcatca ctcctatatc actagtgtta cactgatttg
    10801 taaaaaataa tagcaatttt gctcttattt ttttgagtaa atagctccca taatatcatc
    10861 gaaataatca acggtattta ggagtaattc aataacctgg gactttgtta gtcgcattcc
    10921 ccttctatct ctagcatctt ctactaaatt ttcaagtttc tctagatttt tatcatccaa
    10981 gctaatcatt attctatttt tatcggttgc cattttcatc acctcaagtt aattctatca
    11041 caggtgtaac acttgtgtca actggctttt ataatacatt agtttaaaag tggagaggat
    11101 ttttaacaca gtaactttaa atctttggta ttaaaaaatt ttcacaatat ttatagaaat
    11161 aaaatctgtc tcaaatcagt tatcaaatct agtataaatt atgagcggct actctaatac
    11221 tttccctcta aacaagaaaa agacttacac tcaaggattt tcttcccccc cttcgttata
    11281 acgttttgac tcttttacta gcaaaggtat atactcacaa ggaactttgg ttgactattg
    11341 aatctctcca acttcttctt taacatatcc ttctacatct tcaatctcta caaacattgg
    11401 gtctaagtga cacaagaaat gccaaacttc gatccctttt tttctgtaaa gaatcgcttc
    11461 accgtcttca cttccgaaaa agcttctgtc gatttcatat ccgcggcttt ctaagaagtc
    11521 ttttgcttta cgatagttcg tttctcttgt ttcgacatag gttttaactt catggttgtt
    11581 aacgacatat gcatcaattt ttgaatatcc ttcgatcact ctatcatttt tgagggataa
    11641 atttgaaatc tctttccaaa taatgtttac attttcctca ggatcgaaca taaatttaga
    11701 taaaggaaca atatttccgt taaaaataat ttccatataa tccggtatgt ttttaggatt
    11761 aaaatactcc acttcaaaac catcttctgt ttccagagtg tatcccggga tttgagctac
    11821 aaaggctttc ccatcttcta tggaatcaaa tgctactaaa tctttagaat aatcattttg
    11881 gtacaattcc aatataacca tcgataatct ctccattttc attatcaggc taatgtaaat
    11941 aagcacgtca cctgaccaat tcaggctctc tgtatcatct catcatattt cctacttact
    12001 ttacgagtcc tatacccaga acacacctta tcgaccttcg gtctcacctc gttgcattgg
    12061 ctgaacatct acttttactt cgctgatgct tcaactcgta caagcagtga taccgcctca
    12121 gcgtgatgcg tcagtgggac tcaaaaggtt cggggaacct tttgaggatt aactacgttt
    12181 ctctaataaa cttacacatt caacttgttc atcattgtcc aaacctatgt tgagattttc
    12241 ttctataatt ggtagcttaa aagtaatgga ttttagccat tgtccgttag attgtttttc
    12301 ttcataaact tgaatttcag aaatcaaagc tgaaattaac tgcctacgct ctacatcatt
    12361 catgacttta tagagcttat caaaatagat cagaacctta tatatgttat ctcctgtaag
    12421 cttttcagct tcaatagtct gtttctttgc tttcgcatca attagtgatg attctaattc
    12481 atctactttg tcatacatac gatatagtct atcatctaaa tcctgtttcc ttctcttata
    12541 atgcttatct tcaacatcta aattatctat ttcctcaatt agcttaaact ttgtagaatg
    12601 actctttctc aattcctttt ggtaattatc tatttctttt tctatttcag aggtatccac
    12661 cttcatgttg attttttctt gcatcataga agcaaatttc ggattactta ctatcttgac
    12721 aatcacctct gcaacagcat catctaacaa ttcttctcca atttgcttac tgaatgtaca
    12781 cttatgacct cttatcatct gcctatggtt acaaccatag taataaaaat ctttatactt
    12841 tgtgccatct ttctttttct tgatacactt gttcccaaac attcccactc cacatatcgg
    12901 gcattttaca attccagaaa gcaagtgtgt gcgtgtatct tttcctttat tcacatgctc
    12961 atatttcttt gcttgagatt ttagcttaac ctgagcagct tgccaaactt catcggaaac
    13021 tatagcttca tgtatccctt cagatattag atattcatct tgttcaacct gcttatattc
    13081 atttcttgta ccatgaactt tttctaaagt tcttcttcca aatgctattt tcccattata
    13141 tacaggattc tttaatatct ttcttataag acctgcatca aacaaaggat tcttaccatt
    13201 ctgtcttggg atttttctaa ttccatgatt ctctaagtat ttagatatcc cattggctcc
    13261 tatcgtagta tttacatact ggtcgaaaat cgttcttatt gcaactgcct cttcctcatt
    13321 tataaacagc ttgccgtctt caagtttata tccatacgga gcaaagccac cattccattt
    13381 tccttccctt gctttttgaa tgcgaccttc cattgtttga atacggatgt tttctctttc
    13441 tatttcagcc acagctgata aaacagaaat cattagtttc ccagcatctt tagatgaatc
    13501 aatgccatct tcaacgcaga taagattaac tccataatcc tgcattatct gaagtgtaga
    13561 aagaacatca gcggcatttc ttgcaaatct tgataactta aacacaagaa caaaagatac
    13621 tccatctttt ccagatttta tatcttccat cattcgattg aactgtattc taccttcaat
    13681 agacttgcca gacttcccgg catcttcata ctctccaaca atttcataat cgttgtaaat
    13741 agcaaaagct ttcattcgtg atttttgtgc ctctaacgaa tacccctcta tctgtattga
    13801 cgtagatact cgtgtataga ggtatacttt tattttttct tttgacatag tattaatctc
    13861 aatataattt ttctatatca tatataattt ttttaattta agtttggact atcatttcaa
    13921 gtatattata acacttttat tagtccgtct caatttgtgt ttttgccatg tcaaaactat
    13981 ttttcatctc ttgatttttt gctggcgttg gatcgggtag attatctaaa tctaaagcac
    14041 cagcatattt tgcaatcaga tttgctatta aatcagccaa tccattccag tcattgtcca
    14101 atatatacct cctctaaagt tttatatcta ataattattt gtttaattaa gttttttgac
    14161 attgacaagt gctttggatt agcaacatag gaatctcacc tccgcctcta ttccggatga
    14221 gccggcttca accttagaag tatcattatc ctcattttct tcatagcgga tagggtatcc
    14281 ctccctatat tcaaactctt acttatcgct cactttcttt ttacttagca gaactttttt
    14341 tgccgaatta ttcagccgaa agatcttgac ggataggtta ttacgctcca aaaataatta
    14401 acgtcttgtc ttggtctatt caattgttaa ggttcaaaat ttatcgagag ttattaatct
    14461 ttttaaaatt tgaccatcag aaaatattta tcttaatgta acaaaattct ataaattacc
    14521 ctcttatact taacagtgaa aagaagtctt tcttggtaac caattttgaa atagaatttg
    14581 cttatataaa aaggtcaaat tcccactgca taagtagcag tgaaaattag accctcttgg
    14641 taactgtcat ctaaaagtct tctagcattt ctttaatttt ctaatcgcct ttaaagtgtc
    14701 atatttatat ttttttatct ctggcatact ttgatacctt tttagactta aagtctttaa
    14761 tagtgccttt ccacctcttt ttatctataa agattctcct acatcataat tcattttttt
    14821 atttaaacct ttctgtctta gtttgtcttt atcttcttca taccatttta agattgtcac
    14881 atagtggttt tgataggtct taccactgct ttccatgtat ctggatagtt tatttatcat
    14941 tatatctgtg tgtgagttta atttttcttt tagattttta tattcttctt tgcttaacct
    15001 tacatttttg aattctccat aaaaaatggg ggtggacttt ttatctatct ctccctctct
    15061 ctctttatct atctctatat ctttccatgt aattccaatc tggagtacct ctactgtcta
    15121 tcggtaattt aattttgata tctggcaata ctgtgctaga tatttgatct ttatattcag
    15181 tattttttaa agcttgccta ataattgaag ttaaatagaa tgctacttct ttattcaatt
    15241 ctttattttt taattttaaa caatgaattt tcatatctag gcttgcttta tatttatgat
    15301 aaaagactgc tcctaaaaat gaaacagata taaaattttc aaaaactcta taatttttat
    15361 catctatatc ttcgtagtaa cctaagatac cattgtcaat atttgtagca ctaattctag
    15421 gagtttttcc atcgagtaaa tatctttttg gaatagatga gcctgttggt acttgactcg
    15481 atttcccctt tttttcggta ataaatattt ctttttattt tgttgtctga tatttttcct
    15541 acctgtcctt tgtaggatga gtattttcta gattttcttg aataactttt tacttgaagt
    15601 tttagctttt gaactagtcg ttgtactttc tttttgttta ttatcagtcc tgatcttttt
    15661 aatattgctg ttattctcta tatcctattt ttcattcatg atattctttt actaatttta
    15721 tcttaaattc tgtgctgtat ttgccattaa aaaactgacc tcctttagtt agttttttgg
    15781 cctaactttt gagggtcagt tcaaaatttg cgacttttaa atgaattcca atattcaatt
    15841 attaagagct aacatggtgc ttgccaatag gaatcattag aggcgaattg gaaatagggt
    15901 cacgtataat ttttgcttca agattaaaga tatctttaac tagtttatca tttagtatat
    15961 cttcaggctt tccctctgca acaagtttac cttctttaat tgcaaatagg taatcagcgt
    16021 atcttgctgt tagatttata tcgtgcaaaa tcatgcaaat ggttgtctta tatttttggt
    16081 ttagatcagt caagaggtct aatagttcta tttgatatga gatatccaag taagtagttg
    16141 gctcatctaa aagtaggata cttgtatctt gggctagggc tagagctatc catactcttt
    16201 gcctttgacc cccagaaagt tcttcaacta ggttatttgc tagatcttca acattggcct
    16261 taaccattga tctgtttatt atttcaaggt catcttttcc aagactctta aaaggctttc
    16321 tgtaggggaa acgaccacgg cttacaagat cagctactgt tattgattca gggattattg
    16381 gagattgagg taatatagct atgtgttttg ctaaatcttt ttctttataa gaattaattg
    16441 atttattatc aagcaatact tctccctcta atggctttat aagtcgagac aaggttttaa
    16501 tgagtgttga tttcccacaa ccatttgacc caataataac tgatattttt tcttcaggta
    16561 tttttatatt tatattttcc aagattattt tttcatcata accgcaggta agattatttg
    16621 accacagacc tttcattata tattcctcct gttcattttt attagtaagt atattaagta
    16681 tggtgaacct aacaagccag ttacaacacc tactggatat ctagctggta aaatattttg
    16741 agagaatatg tctgataaca aaactagtaa aattccaacc aatccagcta atattgggct
    16801 tcttttcttg ccaatattta aggctatggg accagctaaa aaagatatac aagctattgg
    16861 tcctgtaatt gaagtagaaa aagcagttaa agatacagcg caaaaaatta aaacaagcct
    16921 tgaaagctcg ggatttgctc caagtccgat tgctatttct tcaccaagtt caataatttc
    16981 tagtctttta ttaaaaaata aaactaatat agtagcaata atacttacta ttagaacaag
    17041 aggtatgtca tctaactttg taaaagataa agagccactg agccatctca taacttcttg
    17101 taattcatat cttgctactt tcaacaataa aaatgaggtg cctgctcttg tgacagcttg
    17161 aaaaccaata cctaatatta tcagtcttgc tgctgaaaaa ccatcttttt tagctagtaa
    17221 aaataatatt aaagatgatg ttagtccaca agttattgaa ataattccag tagttaaact
    17281 atttgttttt aataccaata tgcaaaagac cgctgcaata gatgaagaac ttgtgacacc
    17341 gattatatca ggacttgcaa gaggatttct taacatagtt tgaaagataa atcctgccaa
    17401 tccaaaagac cagccagcta taattcctgc taataatttt ggtaatctaa tttccataat
    17461 cgaaaaacta gctccaggaa cagtttcact atttaagact ttaatcaaag ttgaaaaaga
    17521 ataactttca tctccgataa gtaaaatgaa aaatgataga ctgattatta ttaataaaaa
    17581 tagtgaggaa aatagtgtta ttctattttt tcttttttga atacctataa ttaaattttg
    17641 cattagttat taacccctct atttttcata gttacataaa taagtactgg acccccgatt
    17701 attgcagtaa ttatccctac ttcaatttca cctggtttac ctaacatacg gccgattata
    17761 tcacatataa gcaagagctc tgcacctata aaagatgaag aaatggtcat tgtgcgtata
    17821 tctttgctta taaataagcc acaaaagtga ggaactataa gacctacgaa gccaataggt
    17881 ccaccaattg cagtaatact tgaacataaa agcacacttg caattattgc aagtgatctt
    17941 atcctattaa cattaactcc aagaccaaca gccatttcat cacccatagc taaagcgttt
    18001 aaatctgatg aaataaatat agctatcaag tgacctaaaa ttataaaagg tagtagtgta
    18061 gatatagaag ataatgtagc tgctccaagg ctacctattt gccaaaatct aaatttgtct
    18121 aagacgttat tattcggtaa aattaaaaaa cttacaaaac tgcttaaagc catactaaca
    18181 caagttcctg ataaggctag ttttataggg gtaaggcctg cttttccgct tacagcaatc
    18241 gcgtatacaa aaattgcact tactaagcca ccaatgattg caaaacttat atggcttatg
    18301 cttgatgaaa ttcctaaaaa agaaagacca attactacac taagacttgc tcctgtgttt
    18361 ataccgagta tacctggatc agctattggg tttctagtaa ctgattgcat caatacaccg
    18421 cttatggcaa gactagaacc tgctaaaatt gcaaaaatag ttctaggtat tcttttatat
    18481 ataattgatt taataaaatc atcatttgta ttgcccattc caaaagttgc taaaaaatct
    18541 ctgatattaa tttcttttgt tccaagcttt aatgacaaaa atattgtaat aagaagacct
    18601 aggcagatta caaaaattat gcctaggttt atttgttttt tatttcgcat ttttgcatgc
    18661 atttcctaaa agatttaggt attcttcaat agtatagttt attgaaagtg gtgttggagt
    18721 gcatgaggct gctaacggtg tattatctgg aattacagca acggcaccat ttttaattgc
    18781 atttatttta cctaaaagag gatctttttg taaagcttca agagttttat catcaccata
    18841 agttatgatt acatcagcat catttatctt atttgcttct tctgcagaaa tttcctttgc
    18901 aaaactatct tcactctcaa attcttttaa tgattcaggg aaaactagac ctaaatctgt
    18961 taaataattt gctcttggat ctttgctagt ataaatccag aattttgatg tatctgcagc
    19021 attaatcata gtaaataata ctttttttcc tttgattttt cctttgattt ctggatgttt
    19081 ttctaattct ttggatatac gagcttcagt atttttgatt aactcatcac cttctttttc
    19141 catacctaag gcttttgaat caattttaat catatctctc cataaagttt gccaaggttt
    19201 agatttgtat gctgctacag gagcaatttt tgatagagtg tcataatctt ctttagttat
    19261 accagaataa cctgctaaga taacatctgg tttagaattt gatattgctt caaagttaag
    19321 tccatccaaa tcgtcaaata ggttagcttt accatttagt tctttgattt tttcttctgt
    19381 ccatggtaaa actcctttat cagcacttac accgtaattt gcttttgaaa atccaacagg
    19441 aactattcct aaagctaatg ctacatcatg atttccccaa gcaatagttg caactctttc
    19501 aggtttttta tctaatatag tttgaccgaa agcatgatct aaaactattt tatcaggcgc
    19561 atgctcttta gaagtatttt cttcattttt aacagaatta gaagaacaag cgctaaaaac
    19621 tatacacata gctaaaatag ctattagaaa aaatttgttt ttcataaaaa ctccttaaac
    19681 atatttcaag tctattgtat cgataataat tatcattgtc aatagataca gttacaaatt
    19741 taataatata attttttcaa aaaagg
//
LOCUS       DAVBEM010000043        18957 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVBEM010000043 DAVBEM010000000
VERSION     DAVBEM010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18957
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.043"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(21..1376)
                     /gene="rlmD"
                     /locus_tag="VQ548_001567"
     CDS             complement(21..1376)
                     /gene="rlmD"
                     /locus_tag="VQ548_001567"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET2654392.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            1414..2190
                     /gene="recX"
                     /locus_tag="VQ548_001568"
     CDS             1414..2190
                     /gene="recX"
                     /locus_tag="VQ548_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HET2654393.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINANQLSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYFDAKIAFDELDSQVDEETTQELIFKELDK
                     QYTKYARKYEGYKLKQRLTQVLARKGYDFSDIASALREYL"
     gene            2279..2812
                     /locus_tag="VQ548_001569"
     CDS             2279..2812
                     /locus_tag="VQ548_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HET2654394.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(3252..4008)
                     /locus_tag="VQ548_001570"
                     /pseudo
     CDS             complement(3252..4008)
                     /locus_tag="VQ548_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(4146..5768)
                     /gene="groL"
                     /locus_tag="VQ548_001571"
     CDS             complement(4146..5768)
                     /gene="groL"
                     /locus_tag="VQ548_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HET2654395.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(5784..6068)
                     /gene="groES"
                     /locus_tag="VQ548_001572"
     CDS             complement(5784..6068)
                     /gene="groES"
                     /locus_tag="VQ548_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HET2654396.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(6338..6733)
                     /locus_tag="VQ548_001573"
     CDS             complement(6338..6733)
                     /locus_tag="VQ548_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HET2654397.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(6811..7572)
                     /locus_tag="VQ548_001574"
     CDS             complement(6811..7572)
                     /locus_tag="VQ548_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET2654398.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(7605..8231)
                     /locus_tag="VQ548_001575"
     CDS             complement(7605..8231)
                     /locus_tag="VQ548_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HET2654399.1"
                     /translation="MIFTYNKEHVSDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(8247..8564)
                     /locus_tag="VQ548_001576"
     CDS             complement(8247..8564)
                     /locus_tag="VQ548_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HET2654400.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(8561..8860)
                     /locus_tag="VQ548_001577"
     CDS             complement(8561..8860)
                     /locus_tag="VQ548_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HET2654401.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(9145..9336)
                     /locus_tag="VQ548_001578"
     CDS             complement(9145..9336)
                     /locus_tag="VQ548_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HET2654402.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(9497..10171)
                     /locus_tag="VQ548_001579"
     CDS             complement(9497..10171)
                     /locus_tag="VQ548_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654403.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(10177..10623)
                     /locus_tag="VQ548_001580"
     CDS             complement(10177..10623)
                     /locus_tag="VQ548_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2654404.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(10725..11240)
                     /locus_tag="VQ548_001581"
     CDS             complement(10725..11240)
                     /locus_tag="VQ548_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET2654405.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVCVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLFLHVS"
     gene            complement(11237..11599)
                     /locus_tag="VQ548_001582"
     CDS             complement(11237..11599)
                     /locus_tag="VQ548_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HET2654406.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICSVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(11665..13524)
                     /locus_tag="VQ548_001583"
                     /pseudo
     CDS             complement(11665..13524)
                     /locus_tag="VQ548_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(13541..14011)
                     /locus_tag="VQ548_001584"
     CDS             complement(13541..14011)
                     /locus_tag="VQ548_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET2654407.1"
                     /translation="MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQANIKGIGGENKEISQKN"
     gene            complement(14135..14851)
                     /locus_tag="VQ548_001585"
     CDS             complement(14135..14851)
                     /locus_tag="VQ548_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2654408.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(15732..17141)
                     /gene="ply"
                     /locus_tag="VQ548_001586"
     CDS             complement(15732..17141)
                     /gene="ply"
                     /locus_tag="VQ548_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HET2654409.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQHEKITAHSMEQ
                     LKVKFGSDFEKIGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLRQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFESLIKGVAPQTEW
                     KQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTSFL
                     RDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVLTP
                     KAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRKRT
                     ISIWGTTLYPQVEDKVEND"
     gene            complement(17152..17484)
                     /locus_tag="VQ548_001587"
     CDS             complement(17152..17484)
                     /locus_tag="VQ548_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654410.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDYLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(17555..18163)
                     /locus_tag="VQ548_001588"
     CDS             complement(17555..18163)
                     /locus_tag="VQ548_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654411.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(18176..18634)
                     /locus_tag="VQ548_001589"
     CDS             complement(18176..18634)
                     /locus_tag="VQ548_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HET2654412.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            18759..18869
                     /locus_tag="VQ548_001590"
                     /pseudo
     CDS             18759..18869
                     /locus_tag="VQ548_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            18868..18957
                     /locus_tag="VQ548_001591"
                     /pseudo
     CDS             18868..18957
                     /locus_tag="VQ548_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT         5581 a         4205 c         3452 g         5719 t
ORIGIN      
        1 atgttttgtc aacacctttt ttaaactttt tttattaatt ttacaacagc ttcagttcga
       61 gctgtatgtg ggaacatatc gaccgactgg atataatgaa gatcatagac ttctactaag
      121 cgtaccaaat cacgagccaa ggtcgaaaca ttacaagaaa tataaaccat tttttctggt
      181 acataagtaa gaatagtatc taataactta tcatccagac ctgtacgtgg tgggtcaaca
      241 atcaaagcat ctgctcggta gccttccttg taccaacgag gaataatctc ttctgccgtt
      301 ccagcttcat aatgagtatt gtcaaatccc attcttttag catttcgctt ggcatcttca
      361 atagcttctg gaataatatc catacctctg agtgttttta ctttctttgc aaaggcaaat
      421 ccaatcgttc caactccaca ataagcgtca atcaaatggt cttctttatc aacatccagc
      481 gcttttactg cttcgctata gaggacttct gtttgctcag gatttagttg ataaaaagct
      541 cgaggggata gtgaaaattc ataattgagt acaccttctt gaatactctc ttgcccccag
      601 ataatctctg tcttttcacc atatatctca ctggttttag ctgtatttgt attaacagct
      661 actgtcacaa cttctgggaa atctttaacc aactctttta ccaattgagt taaattaagc
      721 tggcggtttg taacaataat aatctgaacc tgtccggtct ttctcgcgcg tcggaccata
      781 atagtacgga cacctagaac ttttctctca tccgtgattg gaatctggtg ataagtaagt
      841 aattctgcta agcgattagc aatcacttgg gtttccttat cttgtaccag gcagtctttc
      901 aactctacta aatagtgaga gttttgtgca tataagcccg ccttgacctg atttttaaat
      961 tttcgagtct gaaattgtaa cttagctctg taatattttg gttcctgcat tccaatagtt
     1021 ggacgaattt cataattttc atatcctgca ggagcaaatt ttttcagcgc ttgatgaagt
     1081 aagtccgtct tgaactccag ctgcttatca taatgcaggt gcatgatttg gcagcctccg
     1141 cattcattat aaatagtaca agatggcaca attcgaaatt tagacttctt gttgaccttc
     1201 agtaattttg cttcaacaaa gttgcgtcta atagaagtaa tctgacaata gatatcttcg
     1261 cctttgagag ctcctggtac aaagactaat gttttttggt aaaagccgat tccctcaccg
     1321 ttaattccca tgcgcttgat ttttaatggt attttttgtt tcactttcag attcataccc
     1381 ctatcttatc acattttgag ttataataga gctatgaaaa tcacaaaact tgaaaagaaa
     1441 aaaagactct atctgatgga gcttgataat ggcgacaaat gctatatcac cgaagataca
     1501 attgttcgtt ttatgttatc gagagataag gtgataagcg aagaggaatt gaaagagatt
     1561 caagactttg ctcaattttc ttatggtaag aatctggccc tctaccactt atcctttaaa
     1621 gcacgcactg aaaaagaagt cagagaatat ctgaaaaaat acgatattga taaaaacatc
     1681 gtttctcaag ttattgctaa tcttaaagaa gataagtgga ttaatgatgg tcagtacgct
     1741 tatgctatca tcaatgccaa tcaactttca ggagacaagg gaccttatgt actgactcag
     1801 aaattagcac aaaaaggaat ttcaaaatct actatagaag aaatcttgaa tgattttgat
     1861 ttttcggaag ttgctcaacg tgtagccaat aaactattga aaaaatatga gggaaaactt
     1921 ccagctcgtg ccctgcaaga taagattatc cagaacttga ctaacaaggg cttctcttat
     1981 tttgatgcta aaattgcctt tgacgaattg gatagtcaag ttgatgaaga aacgactcag
     2041 gaactcatct tcaaggaact tgataagcaa tatactaagt atgcccgaaa gtatgaagga
     2101 tacaaactga agcagcgttt aactcaagtt ttagcacgaa agggctacga tttttcggat
     2161 atagcaagcg ctcttagaga atatctttaa tatttccaag tgaaattcac agattttagg
     2221 taattttatg gtacaatagt aaatgataaa cttataaatt gtagaaagtt ggttagttat
     2281 gaagcttcca aaagaaggcg actttattac aattcaaagt tataagcatg atgggagtct
     2341 ccaccgaact tggcgggaca ccatggtact aaaaacaaca gaaaacgcca ttattggtgt
     2401 caacgatcat acacttgtta ccgaaagtga tggtcgtcgt tgggtcactc gagaaccggc
     2461 tattgtttac tttcacaaga aatattggtt taatatcatt gccatgattc gtgataatgg
     2521 aacttcttac tattgcaata tggctagccc ctactatctg gatgaagaag cactgaagta
     2581 tattgattac gatttggatg ttaaaatttt tacagatggg gaaaaacgtc tcttggacgt
     2641 tgaagagtac gagcgtcaca aacgcaaaat gaattattct gatgacttgg actatatttt
     2701 aaaagaacat gtcaaaattc ttgttgattg gattaacaat ggacgtggtc ctttctcaga
     2761 agcctatgta aacatttggt acaagcgcta tgtagaacta aagaatcggt aaagttgtca
     2821 aaggtcagga acaaaatcct gaccttgttt ttttggtagt ataaaataaa ttgtgtaaac
     2881 acaaaaagga ataaatccat tatagcagag ttacaacaca tttctataaa gaaatttatt
     2941 cctacgactc agtttggcat gcttaacttc ctaactcaaa aacaaagcat cgattaattt
     3001 atccgttctt cttttgaaac agatttgaac tgataattgc tcgttttaat ttaagaagct
     3061 cttttgagca aaacttcatt tttttaagag tccaacaatt tctgtctatc gcttttctac
     3121 tagcaaaaaa cctcccttga ggcaagtttt catttatata tctaatttcg taacagtata
     3181 gtaaaatgaa ataaggacag tcaaatcgat ttctaacaat gttttagaag tagaggtgta
     3241 ctattctagt ttcaatctac tataaatttg atatgagaat agtctttctc aacatcctta
     3301 tccaacaagc atgctgtggc gtccttctta acttgaacca ggtcaatatt ctgggcttgg
     3361 gctgccatag acgcagccac aataacattg acgatagata tcatactcct cacacatctc
     3421 tactgaacgt ttgtagcctt gatttttctt gaaatcgttg ggaagatagt gggtcgtgta
     3481 aattttttgc acatcgattc cgatgctatt gatggtttga gaattcttat gaggactgat
     3541 ggtcaaggct gaaccaaagt agtcaaagcc caagtccata gccacttgcg ctgttttatc
     3601 cagtcggtag tcaaaacaaa ccttgcaacg gtcgccacct tcgggctcct cctctagtcc
     3661 cctaactagt tttcggtatt aattgggttc gtagggagct tctaggtact gaaccgtatt
     3721 tcctgtccga tcattaaaat cactaacaaa tttcttgatg acatagaccc gcttatggta
     3781 ttctactttg ggatggatat tagaattggc aaaatagatg gtcacatctg catacttggt
     3841 caaatattct agtgtatagg tactacaagg ggcacagcaa acatgcacga gaatggttgg
     3901 ccgctgctca tttttctccc atgcttgtac cattttctgc atgacacggt cataattaat
     3961 cttctgattg gggggcatct tgcacagaat ttcttctaca tcgatcatgt tcttctcctt
     4021 tttctagtct tattttatca tataagttag aagagctcaa atcaatttag aagtgaatat
     4081 tataaaaaga agggttagtc attccctcct tttgtgtttt ttataagttg ttttctatag
     4141 aaagcttaca tcatcccgcc catcatactt ggatccattg ctggagctgg ggctactggt
     4201 tctggtttat tggctacgac tgcttctgtt gtcaaaatca agctggctac agatgctgca
     4261 ttttgtaggg ctgaacgact cactttaact ggatcaatga taccttgatc aatcatgtta
     4321 acccactcgc cagttgctgc gttgaatcct ataccaagct cagcattttt caaacgatcg
     4381 ataacgatag atccttcaaa tcctgcattg tgagcaattt gacgaacggg ttcttccaaa
     4441 gcacggagaa caatattacg tcctgttgct tcatctcctg tcaattccaa ggtagcaaca
     4501 gctggaatca cattggcaag agctgttcca ccacctgcaa caataccttc ttcaacagct
     4561 gcacgagtag cgttgagggc atcttcaatg cggagtttca tttctttcaa ctcagtttca
     4621 gttgcggctc cgaccttaat aaccgctaca ccacctgaca atttggccaa gcgttcttgc
     4681 aatttttcac ggtcaaattc agaagttgta gtttcgattt gagacttgat aaccgcaaca
     4741 cggtgagaaa tcgcttcagg atttcctgca ccttctacaa taaccgtgct atctttgtcc
     4801 acggtcactc tcgctgcttg accaagagct tcaattgtcg catctttcaa ctcaagacca
     4861 aggtcttctg tgataactgt tccgcctgtt aagatggcga tatcttcaag catggctttg
     4921 cgacggtcac caaaaccagg tgccttgact gctactacgt tgaaggttcc acgaatcttg
     4981 ttcaaaacaa gagttggaag agcctcgcca tccacatcat ccgcaataat caagagtgga
     5041 cgattgcttt ggagaatgct ttccaaaagt ggcaagattt cttggatatt ggaaattttc
     5101 ttgtctgtaa tcaaaatgta cggattttca aggtcagcca ccattttttc gctatcagtc
     5161 accatgtact gtgaaaggta accacggtca aactgcattc cttctacgac ttcaagctct
     5221 gtttccatac cacgtgactc ttcgatggtg atgacaccgt ctttgccaac tttttccatt
     5281 gcttcagaga tgtactcacc aactttttca gaacgagaag atacggctgc aacttgagcg
     5341 atagcttctt tattggcaac agggatggcg ttgtttttca aagcttcaac tgctgcggca
     5401 actgctgttt caatcccacg acgaataccg attggatttg cacctgctgt gacgtttttg
     5461 attccttcac ggacgattgc ttgggtcaaa acagttgcag ttgtagttcc atcacctgcg
     5521 atatcattgg tttttgaagc cacttctgat accaatttgg cacccatatt ttcaaaatgg
     5581 tcttctaatt caatttcttt ggcaatagtc acaccgtcat tggtaatcaa tggtgagcca
     5641 aatgattttt caagaacgac attgcgacct tttggtccca aggttacttt aacagtgtct
     5701 gcaaggatat cgacaccacg gaccatagct gaacgggcat ctgatgaaaa tttaatttct
     5761 tttgacatac ttactttctc cttctattct tcaatgattg ccaagatgtt agcttcgcct
     5821 acgatgatgt acttttcatc gccatctttg acatcaagac ctgcgtgggc ttcaactaag
     5881 acacggtctc cagttttaac acttggagca accaagtcac cgttcaaggt acgaacacct
     5941 tgtccagtag ccacaacttg ggctgttttg gttttttctt gggctgaacc tgcgagaaca
     6001 aagcccccaa cggtttgttc tttttcttct atttttaaga ccacacggtc ccctaatggt
     6061 ttcaacatct gatttcctcc ataatgagat agatattatt agcgctcttt atacctgagt
     6121 gctaattcat agttctattg tatcacttag tcagaaataa tcaagaaaaa agtctgactt
     6181 tctcaagata aaaagcccga gaccaactca gactttttaa tgtttatact caatgaaaat
     6241 caaagagcaa actaggaagc tagccgcaag ctgctcaaag cattgctttg atgttgtgga
     6301 taaagctaac gtggtttgaa gagattttcg aagagtatta aaatggcaat tcttcctctt
     6361 ccaagactaa atctgccaaa tcttggcctg cattattttc acgcatggca cgttgagcac
     6421 gactttccaa gagttggaat cctgttacaa gtacttcggt cacgtagttc atttggccat
     6481 ttttctcaaa gcgacgggta cgcaattctc catcaacgga aatgagacta cctttggttg
     6541 cgtagcttgc caaagtttct gctagtctgc cccataggac catattgaca aaatcagctt
     6601 cacgttcacc gttttggtct ttgtaacgac ggttcacagc gatagttgct cgcgctaccg
     6661 acttgtcatt gttggttttg tgcaattctg gtgtagacgt taaacgccca atcatgataa
     6721 ctttattata catattttct tcctcctact tatctattcg taggaaatca aaaaaagtta
     6781 cagaaatttg taacttttcg aggaaatttc ttatttttta tgaatcatga aacctgtcgc
     6841 ctgttgattg gccataatgg tcatatctgt aatctgaaca cggcgaggct gactggtcac
     6901 atagactact gtgtctgcaa tatcctgagc ttgcaaggct tctattcctt ggtaaacgga
     6961 cgcagctcgc tctttatcac catgaaaacg aacagttgag aaatctgttt cgacaatccc
     7021 aggctgaatg gttgtcacct tgatatccgt tgcgatggta tcaattcgca gtccatccga
     7081 aaaggtctta accgcagcct tggtagctga gtaaacagcg gcaccagcat aggcgtagat
     7141 tcctgcggtt gaccccatat tgataatatg accttgattg acttttatca ttgctggcaa
     7201 gaaacagcga gtaaccgcca tcagaccttt aacattggta tccaacatgg tcaacatatc
     7261 caactcctca tagtcttgat agggagccaa gtcaagagcc agtccggcgt tgttgaccaa
     7321 gatatcaatc ctccctatcg tttctagaat atcagagcaa acagtcttca ccatgaccat
     7381 atccgtcaca tctagtggaa aagtccagac ggtttgattt ggaaagctta ctgcaaactc
     7441 cgacttgagg atttctaatc tgtctatccg tcgtcctgtt agaacgacat cctcaccctg
     7501 ctccagataa gcacgcgcaa tcgcttcacc gattcctgag gttgctcccg taatcactac
     7561 attttttgcc atcttatttc cttctatcag atgctgacaa gttcctaggc agtccagtgt
     7621 ttcgctgggt cgaacggtgt tccgacaact tggtcttctg ataattcaag caccccacgt
     7681 ttttgcggag catttggcaa atgcaattca cgaggactac acatcatccc aaaactcttt
     7741 tcaccacgaa gttcgcctgg gaaaatgaaa ttcccttttg gcatcatggc accaggaaga
     7801 gccacaatgg ttttcaaccc aacacgcgca ttaggtgctc ctgcaacgat ttgcactatc
     7861 ttgtcacttg cgactgcaac ttggcagatg ttgaggtggt cactgtctgg atgagctacc
     7921 atctcgacaa tttcaccaac aacaaactta ggttccttat cattaacaat ttcttctgta
     7981 aaaccttccg cctgtaattc ttggttcaaa cgagcgactt gctcatctga taaaaagact
     8041 tgaccgcgct ctgcaatttc aaacaagctc gaaacctcaa aaatgttcca agccactgtt
     8101 tccccatttt ctttgaggaa aacacgggct accttgcctt tgcgttccac attcagtttg
     8161 gcatctccgc tatttttcac gatgaccata aggacatcac tgacatgttc tttgttatac
     8221 gtaaaaatca ttgtttcctt tttctcctat ttcaatcctg ctaaaaaatc gttaatttgc
     8281 tccttacttt tacggtcgcg attgacaaaa cgaccgattt ccttgtcctt ttctagaaca
     8341 acaaggctag gaattccgta aacatcccag agtttggcca aatccatata ctgatctcgg
     8401 tccattcgaa taaaggtgaa ctctggattg gtctcttcaa tctctggtaa ggcaggataa
     8461 atataacgac aatcgccaca ccagtctgcc acaaaaagga agaccttctt gcccgctttt
     8521 tccactaaag atgctaattc ttctaaactt gctggctgta tcataagact tcctcctcat
     8581 agactaggtc ttcattttca tagacaaagg tataatgacg gccatcctca aaaatgacgc
     8641 caccaaccaa gctctccaga ctgctttcgt aaacttgaac ataaagggtc gcaatttccc
     8701 ccatgtcgga aaaatggtct cgcacaatct ctgtcaactc ttcctgagtc ttcatgagct
     8761 tacggtcatc tgcaactttt ttcgtagcaa gagcaaggct tccgatacct agcagagcca
     8821 agcctgccat ccacattttt ttagctttca taccattcat tttaacacaa aaaaggcttc
     8881 aggacaaatg aggaagcagc agaaaagcaa gtaaaaagcc tcttccttta aggaaaaaga
     8941 cttcttatac taagagcaaa ctaggaagct agccgcaggc tgctcaaaac acggttttga
     9001 ggttgtagat aaggcgacgt tgacgtggtt tgaagagatt ttcaaagagt attattctta
     9061 ttgccaggca cctaagttgc caacgtagta actatcaggt gtgtaggtat tgcgaagcat
     9121 cttacctgat gaagccagat aatactactt gccattgtct ttgacccaat cattcgcaat
     9181 catggaacca gaagaactta cataatacca ttctcccttg tcataaaccc aagtactgac
     9241 tttcatggtt cctgagcaat taaaggcaaa aaaactgtcc aatatcattc gttttttaaa
     9301 agcatttgac actacatcat ctacgctgta gtacatagat acatcaaacg taaaagccaa
     9361 aatatcgaaa aatatacaac ttttaaaggc agcatttcat tttttaaagt ctaacaacca
     9421 tagaactgaa atcagagcaa ggcatcaatt tcctactctt agtacgtcta ttttgatggt
     9481 tgaagtgaag atttttttat ttaacgtaga caatttccaa cttcccaaaa gccacatctc
     9541 cacggatagt caaggttttg ctggttgggg ctacaggagc gtcagcctta gctgcaccaa
     9601 aggaggtttc tactttcaaa tctacacgcc agtgttgtgg aacatagacg gttgcattcc
     9661 cgaaggccac ttcaatattt aaagttgcaa aatcacctag catctctgca ttatcatagt
     9721 agattttagc atccccaaaa gcgacttcca cttggtcatc tacgagatct tgatcttgct
     9781 tatagaaggt cccgctacca aaagcgactt ccttatccgt gacgactgtt tttttcccat
     9841 tgtaccacca ttttttttca ttccagaact tacttgaatg cgtcagataa ccaacaccaa
     9901 gtaccaccaa gatgctagcc caaataagag aatgattggt aactggtaac aagtcataag
     9961 cgtaatttgc aatgatgagc gccagtaaac ctgtaaaaac tgccgaagtg agatgacgtc
    10021 taaggatgga ctcaatggac ttataagcaa aaaaaacaat acctagtaaa ggccatattt
    10081 taccatccaa agaaggaatt ccaaaattcc cttgcagcaa gatccaagct gctaaaacca
    10141 acaaaacaat accaaatgct ttctttttca tgttttttac ctcatgtttc ttagattttc
    10201 ttttaggagg gattggtaat gccgtgagac atgaacctcc ttgtgcgtct gataaaagga
    10261 aatggtgccc gttcctgaaa aggacttgtc cactgagtaa atctgacgga tgtttgcgat
    10321 cgttgacttg gaaactcgat taaaatagcg aggcaagata gactccaact catagagctt
    10381 gaggcgaacc tcataagctt ccttctggtt atgagcgtag atcttgctcc cttctgtttc
    10441 aaagaagaga atttctgaca ggtctagata atattcacct gtccccttgt aaaaagtcaa
    10501 cctcggagcc tttgactctt gcaagagccg ttgcaagtct gcaatttcat ctgtcaaagt
    10561 gggggtcttg atgacaattt cagtctcctc taaattgccg tcaatctcaa ttcgtaactt
    10621 catcacatct cctttctgac tctactatat caaagctaag ttaggaatac aagggcaaaa
    10681 aagcaagtgg tcaatttgaa gcagtaagtg gttgtaggac tagcttaact tacatgtaag
    10741 aataggaaga aaaggaatcc ccacaccaaa ccacaagcat agccaaccaa gacatccttg
    10801 ggataatgaa caccccctaa aaccctcacc aaccccagca aagctgaaaa gatcaagcat
    10861 actaagccaa taggtagact agcatgcaga caggccatgg agatgatagt tgccgaaaag
    10921 acatggcgac tgggcatcga ccgtcccgaa ctatccttat caagaagggg acagatatcc
    10981 caagtttcat aaggtctcgg gtgattgatt ttcttacgaa acagggacaa ggccacaaaa
    11041 cctgatgcag gaataagcac acaaacccca acttgctgac caagtcctag ttgcaggtaa
    11101 gtggtgacta gcaagatcag atagaccagg ggcatggcga ctgtcatcaa acgattgaaa
    11161 ctgcgtaata ggaataaaag aattggacga ctagttagtc tggagctgat atttcgatac
    11221 cattcttgat aatttttcat ttatgcttct catacttttc tagaacttgt tgagatgttt
    11281 tccccttggc aagccaatcc actagcttgt ccaagcgacg tatttcctgc atcagaggat
    11341 catcaatttc ctcaatacgg acactgcaaa tcttccctgt aattgcaatt cgttcaggga
    11401 cataatatgg tgcttgtcta aaaaaatctc cgtaagtaac atccctatcc agacaagcaa
    11461 gaacatcact cacttcatac cctgtcaacc aactggtcac ttggtgaact gactctgcct
    11521 ttccaccctt tcgctcaact tttgcaatca aggctaagta gacagcagca aatttcatat
    11581 tgtataattt ctgactcata cttctctctt tctatgtgta ctagtataaa taagaaaaag
    11641 aaggccgtca agccttcttt tgatttattc ttctgcttca tcttctgtaa attgactatt
    11701 gtacaagtca gcgtagaagc caccttgcgc catcagttcc tcatagttgc cttgctcgat
    11761 gatatttcca tctttcatga ccaagatcaa gtctgcattt cggatggttg acaagcggtg
    11821 ggcaatgaca aaggatgtgc gtccttccat caaacggtcc atggcttttt ggatcaattc
    11881 ctctgtccgt gtgtcaacag aagaagtcgc ctcatccaaa atcaaaagcg gtgcatcctt
    11941 aagaagggca cgagcaatag tcaatagttg tttttgtcct acagacaagg tcacggtgtc
    12001 atccaagatg gtatcatagc catctggcaa ggtcataata aagtggtgaa ttcccacagc
    12061 cttactagct tccatcattc gttcatcact aatccctatt tgattataga tgagattgtc
    12121 tcgaatagtt ccttcaaaga gccaggtatc ctgcaagacc attgaaaagg catcatgcac
    12181 ttctgaacgc gtcatagcct tggtatccac accatcaatg tgaatacttc ccttatcaat
    12241 ctcatagaat ttcatcaaaa gattgacaat ggttgtctta ccagtcccag tcggcccaac
    12301 aatggcaacc ttttgaccag catgaactgt cgcagagaag tcatagtctt gaacattgac
    12361 accgtccacc agaatttctc ctgctgacac gtcgtagaaa cgtggaatca gattgaccag
    12421 agttgattta ccagaacctg ttgacccaat aaaggccact gtttgaccag tttctgcttt
    12481 aaagctaaca tgttcaataa ctgcctccga atttgccgca tagcggaagg tcacatcctt
    12541 aaactcgacc tgacctttga agttttcatc agtcagctgc acttgaacag ggttttggat
    12601 agaagaatgc aaatctaaaa cttgattaat ccgcttagca gagaccatag tttggggaag
    12661 aacgatgaag agtgctccca tgagaaggaa gtccatgaca acctacatgg cataagacat
    12721 gaaaacaatc atgtcactaa agagaggcag acgcgctatc ggagcagcgt cgttaatcac
    12781 ataggcccca atccagtaaa tcgccacact caaaccactt gaaatcccca tcatgatagg
    12841 attcaaaata gccataagac ggttgacaaa caaatttaaa cgggtcaatt catcatttac
    12901 tgctgcaaat ttttcatttt gataatcctc tgcattgtag gcacgaacga cacgaatacc
    12961 tgttaaactc tcacgagtga tactgttcag tttatctgtc agcccctgaa tcaaggactg
    13021 ttttggaaag gctagcgtca tcaaaacggt cgtcatcagg acgttgacaa tcactgccac
    13081 aagtacggcc cagagccagt attctgaatg acctaaaatc ttcccaatag cccagatagc
    13141 cataattgga ccacacgtta ccacttgcaa gtccatagta atcaacattt gaacttgagt
    13201 aatgtcattg gtagtacgca tcaagaggct aggaattgaa aatttcttaa tctctgtctg
    13261 cgagtaatcc aaaactcggt taaaaatatc acttctcagc ctactagtat aagaagccgc
    13321 cactcgggat gcaaaaaatc caactgcaac tacggacaag aaggcaagaa agggcattcc
    13381 catcatcatg cttgccggct gccacaactc atctaaatta gttccttgac tacctagcaa
    13441 atccgtaatt ttcgagatat aggtcggcac ttccaactct agatagaccg aaaagcaagt
    13501 aaagagaatg gctagtaaaa tcatccccca ttcttttcta ctaattcttt tgactaattt
    13561 ctttattctc tcctcctatt cccttgatat ttgcctgtag ttgaccgaga actttctcaa
    13621 aaatcagtaa ttcatcttca tcaatgtctt ccatcaactg cttgtctatg cgttcaaaaa
    13681 aagccttaac ctgttgcatc tgagaacgtg ctttgtccgt cagacgaaca aacttagccc
    13741 gcttatcaac aggactcgcc tccaattcca ccaaaccatt ttgcactata cgcttaacca
    13801 gattactagc aacagacttg gtaatattga gttcctgctc gatatcttta atcaagacca
    13861 agtcttggtt tttctcgcga ttatccaaaa aatgcacaac ctgaccttgc ggcccaccca
    13921 taaattcaat gccgcaacgt ttggcttcct tttgcaccat caggtgaatt tgatgaccaa
    13981 aacgcttaaa gactaacatc ggtttatcca taatctcccc cttctaaata aaaatagttc
    14041 tctggagaat aattaaattt ctatgagaac tattttcttg attaaaaaaa tcccaagtga
    14101 ttttctcact taggatcatg ttctataggt taaattaaaa cccatctacg ttcgtataaa
    14161 tcttttggac gtcttcgtcg tcttcaagaa cgctgtaaag tttttcaaag gtttcaaggt
    14221 cttcgcctga caattccact tctgactgag gaatcatttc caattcagtc acttggaatt
    14281 cttcaatacc agactcacgg agggcaacga tagccttgtg aaggtcagtt ggcgctgtgt
    14341 aaactgtgat tgtaccttct tgtgcttcta cgtcatccac atccacatcc gcttcgagca
    14401 attgctcaaa gactgcgtcc gcatcttcac ctccaaatac aataacacct ttgttgtcaa
    14461 agaggtaaga aacagaacct gaagcgccca tgtttccgcc gtttttacca aaggctgcac
    14521 ggacattggc tgctgtacgg ttgacgttag aagtcaaagt atccacaatt agcatagagc
    14581 catttggccc aaaaccttcg taacgtcctt ctgtaaaggt ttcgtctgtg tttcctttgg
    14641 ctttatcaat cgctttatcg ataatgtgtt ttggcacttg ggcttgttta gcacggtcga
    14701 taacgaattt caaagctgag tttgattctg gatctggatc acctttttta gctgctacat
    14761 agatttctac accaaatttt gcatatactt tagagttggc tccatcttta gccgttttct
    14821 tggctacgat attggcccat ttacgtccca ttaggaatct ccttttttca cattttaatc
    14881 tttcttatta taacacaagt ttttttgatt ttcactagag gaaatggatt ttattagcaa
    14941 atcaagctag gatagcactt tacctgctaa gatggtcttg cctttctatc tttatcaaca
    15001 gacactcatc cacattcaaa aaacaaacta gaccattatc tgcaaataga aagtttcagc
    15061 caagtttgac aaagtcagct caaattactg tttgaagttt gtagatataa gcgacaaaaa
    15121 caatcatact gcaccttttg ttgacagtct actccagaca tatcatagtt caagtaaata
    15181 ctttgaaatc caacagttct tataggcgct attgtattct aagaaatcaa tagaagagtt
    15241 tctaagcaaa cctctaatac tcaataaaaa tcaaagagca aactagaaag ctagccgcag
    15301 gttgctcaaa acactgtttt gaggttgcgg atagggctga catggtttga agagattttc
    15361 gaagagtata atttacgtgt tcctaagatg gagaagttag actagtacac tggcacttct
    15421 aaaccattgc tagcaattga tttgttcata tttaatttca ttttttccat aaatgggtat
    15481 tagatataaa cagcaaaata tttccgatac gtgtcattct tgaatttcca atcatctaaa
    15541 acaagtaaag gataatcaat cccctgtata tcaaggaatt ggctaccctt tttacttttt
    15601 tacacatcct gtttgataga ctcattttaa catcacgagc atactccaat ggaaatcgct
    15661 aggcaagaga taaactttca gatattcgca gagagctcat cgcctctttt tgtcgcaaac
    15721 attcttctct cctaatcatt ttctacctta tcctctacct gaggatagag agttgttccc
    15781 caaatagaaa tcgtccgctt acgcactagt ggcaaatcgg ttttttcata aaccgtacgc
    15841 caccattccc aggcaagccc ggtacactct ctaattttga cagagagatt gcgaacattc
    15901 ccttttaaag gaatactagt ggtaaagtga gccgtcaaat cctgcccatt tctgtcccaa
    15961 gccttaggag tcaagacttc cttgccttga tgatcatagg ataattcatc ccaagtaata
    16021 taatattggg caacataggc accactatga tccagcagta aatctccgtt tctgtaagct
    16081 gtaaccttag tctcaacata gtctgtactg ttttgaaagg tcgcaactac attgtcacgt
    16141 aaaaaagaag ttgtatagga aatcggcaag cctggatgat cggctgtaaa gcgactgcct
    16201 tcttgaatca agtcctctac catatccacc ttgcctgtta caactcgggc acccgaactt
    16261 gggtcgcccc ctaaaataac cgccttcact tctgtattgt ccaaaatctg cttccactct
    16321 gtctgaggag ctactccttt tatcaaagat tcaaaagcag cctctacttc atcactctta
    16381 ctcgtggttt ccaacttgag atagacttgg cgcccataag caacactcga aatatagacc
    16441 aaaggacgct ctgcagaaat tcctctctgc cttaaatcct ctaccgttac agtatcttga
    16501 aacacatctc ctggattttt aacagcatct acgctgactg tataataaat ctgcttaaaa
    16561 ttaacaatct gaatctgctt ttcgcctgaa tggacagagt taaaatcaat atcaagagaa
    16621 ttccctatct tttcaaagtc agaaccaaac ttgaccttga gttgttccat gctgtgagcc
    16681 gtgatttttt catgctgcat tctagctggg acattattga cctgaccata atcttgatgc
    16741 cacttagcca acaaatcgtt taccgctccg cgaacacttg aattgctggg gtcttccact
    16801 tggagaaagc tatcgctact tgccaaacca ggcaaatcaa tactataagt catcggagca
    16861 cgatcgaccg caagaagagt gggattattc tctaacaagg tctcatccac tacgagaagt
    16921 gctccaggat agaggcgact gtcgttggta gctgttacag aaatatcact tgtatttgtc
    16981 gacaagctcc gcttctttct ttcgataaca acaaactcat cgggtagctg attaccctct
    17041 ttgatgaaac gattttcaat actttctccc tgatgggtca agagtttctt tttatcgtaa
    17101 ttcatagcta gtataaagtc atttactgct ttatttgcca tcttctacct cctaataagt
    17161 tcctggattg agttgcataa actcagactt gttcagcgaa atcagccgtg gttggactaa
    17221 gtaatccaaa atttcctcgt acaattcttc tgagacattg cgtcgccgtc tggctaaata
    17281 agaagtcgga atgaccgtat tatccaacat aaatacctta tctaagtcaa tcaaggttgg
    17341 tcttgtaaaa ggattacgag ctagatccgg ctcttctatc ataaagttct tgaccaaacg
    17401 tctggtcaag agagctggtt tgaaggtctg atttttaacc aactctttgt ttttagtcat
    17461 gctgttgtca atacagatat acatatgatt cttcacagcc aaatcgctac taatagtcgg
    17521 aaaaggcaaa taaagagcta caacatctcc tctcttaatc aagcaagagc accccctttt
    17581 ctcctaatgt aacatagaca ggattgacca agtcttctga ttgactcaga atttccaaag
    17641 tttgagtttg gcgcgctgtc aatttagtag catcttgtct cttcaataca aaatgcttgt
    17701 cgccaataac cttgacaata taatccttct ccaaagctga ctggtaaatc cacatcagat
    17761 gttgtctgtc ctgagaactc aagagagaag gattttcaag cctcccgata gtctgataaa
    17821 aatcaaaaac aggagctaac tcctgccaat ctgattggct agttgtcaag gctagaaaaa
    17881 gggctttgcg agctgatact tcttggttag ccttgagagt tactttcccc tccaagtttt
    17941 ttagaaatcg ggaaactcca gaaagcaaat ttttctctaa ctgcgagaaa taaaaacctt
    18001 tcgttcccag acataagtct ttcatgtcgc tttctctagc aaataagagc tcaaacattt
    18061 gatagtaaaa gaaaaatatc tggcactggg tcgcgctcat cttttcctta tcggcttctt
    18121 tttttaacca gagcaagggc gacaggtagc tggattgaga catttcctct acctcctact
    18181 cttttttaac tggagcatct gcactagctg ccacttcttt tgactggata ctttcccact
    18241 ggttaatctc ctctgagata agaccttcgc atgtcttgac aaatagggca aaagccttgg
    18301 tctttcctgc atatttctcc gtttggcatt gatagaggaa tttttctttc tccaggagtt
    18361 gcgcagtttt ttggtaagaa atccaatttt cctttgcatt atacaaattg ataatcccct
    18421 cacacagcaa gccgagactg gataaggcaa ccgaaatcaa acggtagcga tcacctggca
    18481 taggaatagc acaaaagaca gctatgagga aacctgccac gatttctgtt atttttaata
    18541 ccttatagcg cctacgatgt tgaacgcttt tctttaaaaa atgagctatc tgtacgtcta
    18601 atcgctctgt caggtacatt tcttctggcg tcatattcgt aactcctttc atttactttg
    18661 ataaccatag tataacatat ttgaatatca aagtatagta aaaactggac tataacttat
    18721 tagactccct gcgaaacaaa atatggtata gtagttctat gaattatgaa gcaagtaaac
    18781 aattaactga tacacgattt aagcgtcttg ttggtgttca gcgtaccact tttgaagaga
    18841 tgttagctgt attaaaaaca gcttatcaaa aaagtcggac aagctggtaa aatcttggct
    18901 gacagtggtt atcaagggct catgaagata tatcctcaag cacaaactcc acgtaaa
//
LOCUS       DAVBEM010000044        18810 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVBEM010000044 DAVBEM010000000
VERSION     DAVBEM010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18810
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.044"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            2..391
                     /locus_tag="VQ548_001592"
     CDS             2..391
                     /locus_tag="VQ548_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET2654413.1"
                     /translation="MPFTRLFCLVLVSIDYINCLSETADKNWHKSDRIFVTNTGKTVH
                     SSILSKSLQRANERLKKPIPKHLSPHIFIHITISILSENKIPLKTITDRVGHPDSEVT
                     NSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(883..1293)
                     /locus_tag="VQ548_001593"
     CDS             complement(883..1293)
                     /locus_tag="VQ548_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001124848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654414.1"
                     /translation="MPKKKIERISVIHREKILWLKWYFMRDKEKPKYSVLECKMFDAA
                     KNKDMLAYKKYATIKQITDIRVQTSEDDILTAIKEVYVYNHMNVIGACQRILFVSQSP
                     AYNKLNKWFETYSDLYFSIIPLPNMGAYHELVDS"
     gene            complement(1311..1688)
                     /locus_tag="VQ548_001594"
     CDS             complement(1311..1688)
                     /locus_tag="VQ548_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654415.1"
                     /translation="MRKYLKEIKELQELKELLSSRNTPEVIIVEGNDDLGEFFQVDGE
                     LFSDIELLENLKKWREWEVQVIVDDWCNRGLNEYETGILYFPKHEDKMDYIRFNKGLE
                     PLYHALDEPYTTISKSEWLKLLD"
     gene            complement(1630..2058)
                     /locus_tag="VQ548_001595"
     CDS             complement(1630..2058)
                     /locus_tag="VQ548_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HET2654416.1"
                     /translation="MAGNENDGLTSKQIKFIDAMLTEPTIDKACQKAGVSRATGHKYL
                     KVAAVKKTLRLKQDEMMDKTTQMLYLASSNAVSVLNDIMMDAKINPFIRTQAAKTILE
                     QSYKTHEIFGVVRQIEELRLEIEEVSKGDQRVTRTQGIIK"
     gene            complement(2102..2707)
                     /locus_tag="VQ548_001596"
     CDS             complement(2102..2707)
                     /locus_tag="VQ548_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654417.1"
                     /translation="MTFTTIKDDIKAFGKKKHGYMTGYIAKQEELHKQLQNGMIGEKY
                     AKDQLEAYKLEGDTYSRDTYNKIHAEIEKQHDLELEALKEKELSVTADDVAELTLLAS
                     MKMTKDELLGYFEKYKNKPLAIKKLWSIAEQYPEIAINLELFNAEQALESLILFFKRQ
                     LSYCHYSLLINGDKIQAVTTEMVVNSDAPELDRRLDEYLNK"
     gene            complement(2797..2970)
                     /locus_tag="VQ548_001597"
     CDS             complement(2797..2970)
                     /locus_tag="VQ548_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654418.1"
                     /translation="MTENKDNKLLEMMEKGFVLYSKNGIIKYIEIPDHGSIKLKAQDG
                     QLVYKEVTTGEQC"
     gene            complement(3569..4465)
                     /locus_tag="VQ548_001598"
     CDS             complement(3569..4465)
                     /locus_tag="VQ548_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET2654419.1"
                     /translation="MKSLQSSLGNIETFKLDELCPKHEIQLTQIKGERHVVVGWNENG
                     EVIKEVRCIPPYCEQCQEEQKKQDEEDAIADNLNAKLYLQTYNVLMSNKSYVADEFKT
                     KTFDDFNAVTSEEKRFLEFAKGQVQKYLDGMRGNTLITGGTGIGKTLLSVAIAKGINE
                     GYKTKGEPKSVLFVSLTEMIKQIKEGWNYGKGATLTEFEATELMKSVDYLIIDDLGAK
                     NAVIKPKSDWEQDLLFDVLNNRENTIFNTNLDSDELKIVYNERNYSRILKGLEGNTFK
                     AFTIKDKRYSINQLKNKVKQLK"
     gene            complement(4477..5286)
                     /locus_tag="VQ548_001599"
     CDS             complement(4477..5286)
                     /locus_tag="VQ548_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HET2654420.1"
                     /translation="MAKTKVYFWLKIDKKFFDNIFIKRLKTVPGGYTMTVIYIRLMLE
                     SLESDCILYYEGYFNNLKEELALKLDVSEDDIDMTMAYFTKCGLIQIDEDKNAELPQA
                     KAMVMSETNWASYKREQRKKGKLEEVQPSLTFSNSCPTEIEKELEIEVDKEQSPTPST
                     INQDFVNLYKSFEAETGKALSPLQIQELQYMLEDFSPELIHEALKEAVSQGKANFAYI
                     KAILNRWKQDNLLTVELVRNSRAAREAKKQQTNQLEPTSYEDWIPTQEKPF"
     gene            complement(5361..5576)
                     /locus_tag="VQ548_001600"
     CDS             complement(5361..5576)
                     /locus_tag="VQ548_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654421.1"
                     /translation="MNELDISNTQAVFVTVILIGLLLYLNHRDRKKSAQLERENQQTI
                     ETPSEDLNPDYGRYIQLAGVDVWGRIE"
     gene            complement(5578..5778)
                     /locus_tag="VQ548_001601"
     CDS             complement(5578..5778)
                     /locus_tag="VQ548_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654422.1"
                     /translation="MTLDLDNMTQAEFDEAMAEIQLQSPNIFQLISDFVNKKVTSVEI
                     DDLLNMKRAEQVAYIKNYKARA"
     gene            complement(5775..5966)
                     /locus_tag="VQ548_001602"
                     /pseudo
     CDS             complement(5775..5966)
                     /locus_tag="VQ548_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841301.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5955..6245)
                     /locus_tag="VQ548_001603"
                     /pseudo
     CDS             complement(5955..6245)
                     /locus_tag="VQ548_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424675.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
     gene            complement(6415..6567)
                     /locus_tag="VQ548_001604"
     CDS             complement(6415..6567)
                     /locus_tag="VQ548_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654423.1"
                     /translation="MKIVTFKPTKQIDGGFYLPGIDILFVSDKADAKSTEDVILFISR
                     NGLNKS"
     gene            complement(6578..6844)
                     /locus_tag="VQ548_001605"
     CDS             complement(6578..6844)
                     /locus_tag="VQ548_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654424.1"
                     /translation="MEILSKEIQLQGLQLLKQTLETLVELEKQRSSKLDLISRKELMD
                     LLGISATTLDNWEDLALKRYQTPMDGAKKVFYRLSDVYLFLAIK"
     gene            complement(7055..7237)
                     /locus_tag="VQ548_001606"
     CDS             complement(7055..7237)
                     /locus_tag="VQ548_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET2654425.1"
                     /translation="MLITLSLAEKVRIKRARLQLTKKAVSEQLGIKSQTLTKVENGNY
                     DASKRIYESVMTWLVE"
     gene            7299..7802
                     /locus_tag="VQ548_001607"
     CDS             7299..7802
                     /locus_tag="VQ548_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2654426.1"
                     /translation="MYKMNRIKQLRKENNLTQRELANETKIPYRTIQRWENGETDIKS
                     DAAQVLADYFGVSIPHLLGYSDLIADTDSDIKAMAYSHLLTFVDEKQIKEFEKEFIRA
                     NDNSDTFGDLGSGEKALEKYYQALCYLVPPFRDILARYSFLSLDEKKSVYNIIVGLSN
                     NLSKENK"
     gene            7876..9039
                     /locus_tag="VQ548_001608"
     CDS             7876..9039
                     /locus_tag="VQ548_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET2654427.1"
                     /translation="MNIIEKIKKNGQRVYYASVYLGVDQLTGKKARTTVTATTKKGVK
                     VKARDAINTFAANGYTVKDKPTITTYNELVKVWWDSYKNTVKPNTRQSMDGLVRVHLL
                     PVFGDYKLSKLTTPILQQQVNKWADKANKGEKGAFANYSLLHNMNKRILKYGVAIQVI
                     QYNPANDVIVPRKQQKEKAAVKYLDNKELKQFLDYLDTLNQSNYENLFDVVLYKTLLA
                     TGCRISEALALEWSDIDLESGVISINKTLNRYQEINSPKSSAGYRDIPIDKATLLLLK
                     QYKNRQQIQSWKLGRSETVVFSVFTEKYAYACNLRKRLNKHFDAAGVTNVSFHGFRHT
                     HTTMMLYAQASPKDVQYRLGHSNLMITENTYWHTNQENAKKAVSNYETAISNL"
     gene            complement(9193..10497)
                     /gene="eno"
                     /locus_tag="VQ548_001609"
     CDS             complement(9193..10497)
                     /gene="eno"
                     /locus_tag="VQ548_001609"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HET2654428.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            10661..11107
                     /locus_tag="VQ548_001610"
     CDS             10661..11107
                     /locus_tag="VQ548_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HET2654429.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(11104..12219)
                     /locus_tag="VQ548_001611"
     CDS             complement(11104..12219)
                     /locus_tag="VQ548_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HET2654430.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIDVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGRHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(12228..12557)
                     /locus_tag="VQ548_001612"
     CDS             complement(12228..12557)
                     /locus_tag="VQ548_001612"
                     /inference="COORDINATES: protein motif:HMM:NF019887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HET2654431.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGGNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(12511..12873)
                     /locus_tag="VQ548_001613"
     CDS             complement(12511..12873)
                     /locus_tag="VQ548_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HET2654432.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHC"
     gene            complement(12932..14365)
                     /gene="glgA"
                     /locus_tag="VQ548_001614"
     CDS             complement(12932..14365)
                     /gene="glgA"
                     /locus_tag="VQ548_001614"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HET2654433.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(14362..15501)
                     /gene="glgD"
                     /locus_tag="VQ548_001615"
     CDS             complement(14362..15501)
                     /gene="glgD"
                     /locus_tag="VQ548_001615"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HET2654434.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTFLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVRTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(15491..16633)
                     /locus_tag="VQ548_001616"
     CDS             complement(15491..16633)
                     /locus_tag="VQ548_001616"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HET2654435.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(16623..18551)
                     /gene="glgB"
                     /locus_tag="VQ548_001617"
     CDS             complement(16623..18551)
                     /gene="glgB"
                     /locus_tag="VQ548_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HET2654436.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEYGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFAERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDIYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEVIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         5583 a         3938 c         3166 g         6123 t
ORIGIN      
        1 aatacctttt acgaggctct tttgtcttgt tcttgtttca attgactata taaattgtct
       61 aagcgaaaca gccgataaga attggcacaa aagcgaccgt atttttgtta ccaatacagg
      121 aaaaacagtt catagttcta tcttgagcaa gtctctccag cgagcaaacg aacgccttaa
      181 aaaaccaatt cccaaacatc tgtcccctca catcttcata cacatcacta ttagcatctt
      241 atcagaaaat aaaattcctt taaaaacaat cacggacagg gttggtcatc ccgactctga
      301 agtcactaat tccatctaca cccacgtcac aaagaacatg aaagatgaag caatcaatgt
      361 actggataaa gttatgaaaa agatttttta aaaagttttg tccctttttt gccctctaaa
      421 tacaaaaata gcccttcgga taaaatccga ggggctagaa acgttgttaa atcaacggcc
      481 gaacttttga atttcatggt tcgggataaa atagttcact gaactatttt attttttaag
      541 gttatcataa tatcaaatag ttcaattaaa tacgctaaat tactaatata ctttttacct
      601 ttttcattct aaaatgtaaa gtacaaacaa ttacaatata ctagaggggg agtaaaaaag
      661 gtaataaaat tgacgagttc agcaggcaag ggaaatagca cttttcatgg tgttattttt
      721 ttaattcagc aatggagtag ccgcttaatt gatagaaaca aaaagcacct agtttcctag
      781 atgctagcac aatagcccgg attcgaaccg gaatctcctc aattaaggtg caatccctat
      841 atactactca ttgtgctttg gttcattata tcatacaatc aactagctat ctaccaactc
      901 atgatacgct cccatattcg gtaatggaat aatactaaaa tacaaatctg agtaagtttc
      961 aaaccattta ttcagcttgt tataggctgg cgactgacta acaaataata tccgttgaca
     1021 agctccgata acattcatgt gattatacac atagacctct ttaatggccg ttaaaatatc
     1081 gtcttcactt gtctgtaccc taatatctgt tatctgctta atcgtagcgt attttttata
     1141 agctagcata tctttatttt tagcagcatc aaacatttta cactcaagaa cactatactt
     1201 aggtttttct ttatctctca tgaaatacca cttgagccat aaaatttttt ctctgtgaat
     1261 tactgaaata cgttcgattt ttttctttgg catgattacc tcctaaatta ttaatctaat
     1321 agctttaacc actcactttt tgagattgtt gtataaggtt catctagcgc gtgatataaa
     1381 ggttctaaac ctttgttaaa tcggatatag tccattttat cctcatgctt tggaaaatat
     1441 aagattcctg tttcatattc atttagacca cggttacacc aatcatcaac gataacctgc
     1501 acttcccatt cacgccactt tttaaggttt tctaaaagtt caatatcact aaataactca
     1561 ccatcaactt ggaaaaattc tcccagatca tcgttaccct cgacgatgat aacttcaggc
     1621 gtatttctac tacttaataa ttccttgagt tcttgtaact ctttgatctc ctttagatac
     1681 ttcctcaatt tctaacctca attcttcaat ttgtcttact actccaaaaa tttcatgagt
     1741 tttatatgat tgttcaagta tagtttttgc tgcttgagtt cttataaaag ggttaatttt
     1801 ggcatccatc ataatatcat tgagtacaga aacagcattg gatgaggcta gatatagcat
     1861 ctgtgtagtt ttatccatca tctcatcttg ttttagtctc aatgtctttt taacagctgc
     1921 aacttttaga tacttatgcc ctgttgccct tgacacccct gctttttggc acgctttatc
     1981 tatcgttggc tcagtaagca tggcatctat gaattttatt tgtttagatg taaggccatc
     2041 attttcattt cctgccatct attacctcct cgttatcaaa ataaaggggt tgctagcccc
     2101 tctatttgtt taaatactca tccaaacgac ggtcaagctc aggggcatct gaatttacta
     2161 ccatttcagt tgttacagct tggattttat cgccgttgat aagcaaactg taatgacaat
     2221 atgaaagttg ccgcttaaag aataagatta gactttctag cgcctgctct gcattgaata
     2281 attccaagtt gatagcaatt tctggatatt gttcagcaat tgaccaaagt tttttaatag
     2341 caagaggttt gttcttgtat ttttcaaaat aacctagcaa ttcatccttt gtcatcttca
     2401 tactagctaa caaggtcagc tctgccacgt catcagctgt tacgctgagt tctttttctt
     2461 ttaatgcctc tagctctaga tcatgctgtt tttcaatttc tgcatgaatt ttattatagg
     2521 tgtccctaga ataagtgtcc ccctctaact tataagcctc tagctggtct ttagcgtatt
     2581 tttcgcctat cataccattt tgtaactgtt tatgtaattc ctcttgttta gcaatgtagc
     2641 cagtcatgta cccatgcttt ttcttgccaa aagccttaat atcatccttg attgttgtaa
     2701 atgtcatgtt atcctcctta cgaaaaaata aaagaggtat gacaaaagag cgttaaactc
     2761 aattatcata cctctggttt ttccagtcag tatttattaa cattgttctc cagtggtcac
     2821 ttccttataa actaactgcc catcttgagc ttttagctta atgctaccat gatctggaat
     2881 ttcaatgtac tttattatac cattttttga gtataaaaca aagcctttct ccatcatttc
     2941 taataattta ttatccttgt tttcagtcat gaatttctcc tttatttcaa gtgtcccaac
     3001 gggtacggtt gtaagctgag acattttagg gctatctttg agcgacaaaa atgtcgaaaa
     3061 gtcttcagtt cctgtataac cgttattagt tttgtttgct actcattttt gagtcacaaa
     3121 tctgttaagc aaaaatgagt aatagctcgt aagataagta aatctaatac ttgtattcct
     3181 aaagcgttga tataactgat attttcaact atccaacgct ctttactacc ctttttagtg
     3241 tgctttagct catttttgag cttttttgag cttttttgag ttccattttg ggaatgcaaa
     3301 gcaggcgcgc accgtgcatg cttttttctt gctcatagcc tcaccctcag aagtttgccg
     3361 accgagagcg tggggctttt tatttttgta taattaaaaa cagctgcaca atttttgtac
     3421 agctacgacc gaggcagggg cgacctgccg tactttacac tagataatat catctaggta
     3481 gtccaactgt attttatcat attaaaggct acattacaat ttctcaccct gtgaagagtg
     3541 tctatttttg tttaggtttg taagtcgatt acttcaactg ctttacctta ttttttaact
     3601 gattaattga gtatcgctta tctttgattg tgaaagcctt aaaagtgtta ccctcaagac
     3661 cttttagaat acggctataa ttccgctcgt tgtatactat cttgagttca tcgctatcaa
     3721 gatttgtatt aaatatagta ttttctcgat tattcagtac atcaaaaagt aaatcctgct
     3781 cccaatcgct cttaggttta ataacagcat tttttgcacc taaatcatca ataattaagt
     3841 aatcaacaga cttcatgagt tcagtagctt caaactctgt aagtgttgca cctttaccat
     3901 aattccaccc ctctttaatt tgtttgatca tttcggttag gcttacaaaa agcacactct
     3961 taggttctcc ttttgtctta tacccctcat ttataccttt ggcaatagca actgataaaa
     4021 gtgtttttcc aatccctgta cctcctgtga taagcgtatt tcccctcatg ccatcaagat
     4081 atttttgtac ctgacctttt gcaaattcta aaaatcgctt ttcttctgat gttacagcat
     4141 taaaatcatc aaaagtttta gttttaaact catctgctac atagctctta ttgctcatca
     4201 acacattata agtttgcaga tatagtttag cattcaaatt atcagcaatc gcatcttctt
     4261 catcttgctt tttctgttct tcttggcatt gttcacaata gggtgggata cagcgaactt
     4321 cttttattac ctctccgttc tcattccacc ccactactac atgtctttct cctttgattt
     4381 gtgttagctg tatttcatgc ttaggacaca attcgtctag tttaaatgtc tcaatatttc
     4441 ctaaactaga ttgtaatgat ttcattttct gacctcctaa aatggttttt cttgtgttgg
     4501 tatccaatct tcatagctgg taggctctag ttgattggtt tgctgttttt tagcctcacg
     4561 cgctgccctg ctatttctaa caagttccac cgtcaataaa ttgtcctgtt tccaacggtt
     4621 aaggattgcc ttgatgtatg caaagtttgc tttaccctga ctgacagcct cttttaacgc
     4681 ctcatggata agctctgggc taaaatcttc tagcatatac tgcaattctt gaatctgtaa
     4741 cggtgacaat gctttacctg tctcagcttc aaaagattta tagagattta caaaatcttg
     4801 attgatggta gagggagtgg gtgattgttc tttatctact tctatctcta attctttctc
     4861 tatctctgtt ggacatgagt tggaaaatgt caaagatggt tggacttctt ccaattttcc
     4921 tttttttcgt tgttcacgtt tataactcgc ccagtttgtt tcactcataa ccatagcttt
     4981 tgcctgtggt agttctgcgt ttttatcttc gtcaatctgt attaaaccgc attttgtaaa
     5041 gtatgccatg gtcatatcta tatcatcttc tgatacatct aattttaggg ctaactcttc
     5101 cttgagattg ttaaagtagc cctcatagta taaaatacag tcactttcca agctctctaa
     5161 catgagccta atataaataa ctgtcatagt gtacccacca ggtaccgtct ttagtctctt
     5221 gataaaaata ttatcaaaaa atttcttatc aatttttagc caaaaataga cttttgtttt
     5281 tgccatcgtc ctctcccttg ctcatttata attctctacc ttgattagtc ttaatactcg
     5341 cttgtcattc attgttagac tcattcaatt cttccccata cgtctacccc tgcaagctgg
     5401 atatatcgcc cataatcagg gtttaaatcc tcgctaggtg tttctatcgt ctgttggttt
     5461 tctcgctcca gttgggcgct ttttttgcgg tctcggtggt ttaaataaag cagtaagcca
     5521 atcaaaatca cggtaacaaa aaccgcctgt gtattgctta tatctagttc attcatgtta
     5581 tgccctcgct ttgtaattct tgatgtatgc cacttgttca gctcgcttca tattcaacaa
     5641 gtcgtctatt tccacactgg ttactttttt atttacaaaa tcagaaatca gttgaaaaat
     5701 gtttggactt tgtagctgga tttcagccat tgcctcatca aattctgctt gtgtcatgtt
     5761 gtctaaatct agtgtcattg cattgcctcc tcaaacttct ctataagaca acttttattt
     5821 gctttctgag ttccattttt agagttaaaa agaatatatt ttaaggttac agtagcctct
     5881 aaatactcct tttcagcatg ctctatatac gcctgttgct ctgcttcgtt ctcaaaaaag
     5941 tgcttagctt agcgtttaaa gaatgctttg actaggttta gtttgaattg ccgtactgct
     6001 tcggtattct ttagataagt gatcagcaaa gtagcctgtt gctcgttcag aatataggat
     6061 tttttaggtt gtcctctagt gtctaattta tggattttaa atccaagtat tcccaactct
     6121 tcaaagtcaa ccttattttc tcttattaag cgtgtgatag tgtggtgttg tacgtcagca
     6181 cattcagcga tgatctcgct tgtggtatac ggctctttct tgccgtccat gtagactagt
     6241 tccattatgg ttctacctcc tgtataaatt tagctagctt actttttaat tgtctcctct
     6301 agcccttttt agcctctaca acggttttgg ctaacgtgtt agaggctttt ataacggcct
     6361 gtatagctgt ctctatttcc tccgtggaat agtagctttg ttttctaata tcatttaaga
     6421 cttgtttaac ccatttcttg aaataaataa aattacatct tctgtactct tggcatctgc
     6481 tttatctgag acaaatagaa tgtcaatgcc tggtagataa aacccaccgt ctatttgttt
     6541 agttggtttg aaagtaacta ttttcatttc ataactccta ttttattgct aaaaataaat
     6601 acacatctga cagacgatag aatactttct tagctccatc catcggggtc tgatatcgtt
     6661 taagagcaag atcctcccag ttatcaaggg ttgtagcact tatacctagc agatccatta
     6721 attctttacg agaaattaaa tctaacttac tagatcgttg tttttctagc tcaactaaag
     6781 tttcaagagt ctgtttaaga agctgtaaac cctgtaactg tatttcttta gacagaattt
     6841 ccatttatat cctccatttt cctttttata aattaagttg tctttttcct ctaattttga
     6901 taaaataaga agagattatt tagcaaaggg ggttgtccct ttgctaaata cctaacaaaa
     6961 ccacgcgcct tgcctttgct tgagttttgt tatttttcct tagccgtgta cgttggtttg
     7021 gtcgcctgta catggctttt tacttgcgtt aaatttattc tactagccaa gtcatcacgc
     7081 tctcatagat acgcttagag gcatcatagt ttccattctc aacttttgtt agtgtttgag
     7141 atttaatacc caactgctcc gatactgctt ttttggttag ctgtaatctt gcacgcttga
     7201 tacgtacttt ttcagcaagt gatagtgtaa tcaacattgg tttcacctcc cttttttctc
     7261 catttttggc attttgtgtt ataatctctt tagaaaggat gtataagatg aatagaatta
     7321 agcaattacg aaaagaaaat aatcttactc aaagagaact tgctaatgag actaaaatcc
     7381 cttatagaac catacaacgt tgggagaatg gggaaactga tataaaatcc gatgctgctc
     7441 aggtacttgc tgactatttt ggagtatcaa ttcctcactt actaggttat agcgatttga
     7501 tagcagatac agatagtgat attaaagcaa tggcatactc acatctacta acttttgtag
     7561 atgaaaaaca aatcaaagaa tttgaaaaag agttcattcg tgcaaacgat aatagtgata
     7621 cttttggtga tttaggaagt ggtgaaaagg cgttagaaaa atactatcaa gcattatgct
     7681 atttagttcc tccttttagg gatatattgg ctaggtatag ctttttgtca ctagatgaaa
     7741 aaaaatcagt ctataatatt attgttggtt taagtaacaa cttatcaaaa gaaaataaat
     7801 aactttaaac atcatgtata aatacctaac aaaaccacgc gccttgcctg ctgatggaaa
     7861 gaaaggtaca aatacatgaa tatcatagag aaaattaaaa agaatggcca aagagtttat
     7921 tatgctagtg tttatctagg cgttgaccaa ctaacgggca aaaaagcccg tacaactgtt
     7981 acagcaacca ctaaaaaggg cgttaaagta aaagcgcgtg atgcgatcaa tacttttgct
     8041 gctaatggct atacagttaa agataagccg acaattacaa catacaatga gcttgtaaaa
     8101 gtttggtggg atagttacaa gaatacagtt aagccaaata ctcgccaatc catggatgga
     8161 ttggttagag tgcatttatt gcctgtattt ggcgattaca agctatctaa acttactacg
     8221 cctattcttc aacagcaagt aaacaaatgg gctgacaagg caaataaagg cgaaaaaggg
     8281 gcatttgcta actactcctt gctccataac atgaataagc gtattttgaa atatggcgta
     8341 gctatccagg taatacaata caacccagct aatgatgtca tcgttccacg caaacagcag
     8401 aaagaaaagg ctgctgtcaa atacttagac aacaaagaat taaaacagtt tcttgattat
     8461 ttagacactc tgaatcaatc aaattatgag aacttatttg atgttgtcct gtataagact
     8521 ttattggcca ctggttgccg tattagtgag gctctagctc ttgaatggtc tgatattgac
     8581 ctagaaagcg gtgttatcag catcaataag acactaaacc gctatcagga aataaattca
     8641 cctaaatcaa gcgctggtta tcgtgatata ccaatagaca aagccacatt acttttactg
     8701 aaacaataca aaaaccgtca acaaattcag tcttggaaat taggccgatc tgaaacagtt
     8761 gtattctctg tatttacgga gaaatatgct tatgcttgta acttacgcaa acgcctaaat
     8821 aagcattttg atgctgctgg agtaactaac gtatcatttc atggtttccg ccatacacat
     8881 actactatga tgctctatgc tcaggctagc ccgaaagatg ttcagtatag attaggccac
     8941 tctaatttaa tgatcactga aaatacttac tggcatacta accaagagaa tgcaaaaaaa
     9001 gccgtctcaa attatgaaac agctatcagc aatttataaa aaataagggt gacccatttc
     9061 cgggctaccc tcttactata ccaaaaatta gtaggggtag taaaaagggt attaaattat
     9121 aaaaagcact aagggaaagc gccccaaagt gcttatttca aaggctttat agcctataat
     9181 cacataagga gattattttt taaggttgta gaatgatttc aatccacgat attcagctac
     9241 ttcaccaagt tggtcttcga tacgaagcaa ttggttgtat ttagcgatgc ggtctgtacg
     9301 tgaaagtgaa ccagtcttga tttgtcctgc gttagttgca actgcaatat cagcgattgt
     9361 tgaatcttca gtttcacctg aacggtgtga tacaacagca gtgtaaccag cttctttagc
     9421 catttcgata gcttcaaaag tttcagtaag agtaccgatt tggttaactt tgataaggat
     9481 tgagttagca gcaccttctt ggataccacg tgcaaggtag tcagtgtttg ttacgaagaa
     9541 gtcgtcacca acaagttgta ctttcttacc aagacgttca gtaagagctt tccaaccatc
     9601 ccagtcgttt tcatccatac catcttcaat agtgatgatt gggtatttgt taaccaattc
     9661 ttcaaggtag tcgatttgtt ctgcagatgt acgaacagca gcaccttcac cttcaaattt
     9721 agtgtagtcg taaactttac gttctttatc gtagaattct gatgaagcac agtcaaatcc
     9781 gataaatacg tctttacctg gtacatatcc agcagcttca atcgcagcaa ggatagtttc
     9841 aacaccatct tcagttcctt cgaaacgagg agcgaatcca ccttcgtcac ctacggcagt
     9901 ttccaaacca cgtgatttaa ggattttctt aagagcgtgg aagatttcag caccgtaacg
     9961 aagggcttct ttaaatgttg gcgcaccaac tggcaagatc atgaactctt ggaaagcgat
    10021 tggagcgtca gagtgagaac caccgttgat gatgttcatc attggagttg gaagaacttt
    10081 agtgttgaat ccaccaaggt agctgtaaag tgggatttca aggtagtcag cagcagcacg
    10141 agctacagcg atagacacac cgaggattgc attcgcaccc aatttacctt tgttaggagt
    10201 accgtcaagt gcgatcatag cacggtcaat agcttgttga tcacgtacat cgtagccaat
    10261 gatagcttca gcaatgatgt tgtttacgtt gtcaacagct ttttgtgtac caagaccacc
    10321 gtaacgagat ttgtcaccgt cgcgaagttc aactgcttcg tgttcaccag tagaagctcc
    10381 tgatggaacc ataccacgtc cgaaagcacc tgattcagtg taaacttcta cttcaagtgt
    10441 tgggttaccg cgtgagtcta ggacttcgcg agcgtaaaca tcagtaataa ttgacatttt
    10501 ttactctcct tatgagttaa attttttaca cctctataat accttaaaac ccctcctttt
    10561 tcaagaaaaa acgttatctt tgtgcaactt ttccttaact ttataaagta atcgctttct
    10621 tttgtctgtt ttattctaac ttttatgata tactgttttc atgacagatt tatcaaaaca
    10681 attacttgaa aaagctcatg gtgggttaaa aataaatccg gatgagcaaa gacgctatct
    10741 tggtactttt gaggaaagag ttcttggata tgtagatatt gacacagcaa atagccctca
    10801 gttagaaaaa ggctttttat ttattttaga aaaccttcag gaaaaagcag agccactatt
    10861 tgtgaagatt tcaccaacta tcgaatttga taagcaagtt ttctacttaa aagaagcaaa
    10921 agaaactgat agtcaagcca ccatagtatc tgaagagcat attacttctc cttttggcct
    10981 ggttattcat agcaatgcac cagttcaagt agaagaaaaa gaccttcgac ttgcttttcc
    11041 aaaactttgg gaagttaaaa aggaagaacc agccaaaaca tccttatgga agaaatggtt
    11101 tagctaaatc ttgcacatat ttaataagtg cccaatattg gcagccgtgc gctccagata
    11161 gagactggca tttttcaaac tatcttctaa aggttcactt ttctccaaaa tagaaaagac
    11221 agcttggata ttttcaaatg gtaggggagg taaatcttca gcaagactac cgcaaatagc
    11281 aataacagga actccaacag gggttctttt tgcaacacct ataggcgctt tcccagcaaa
    11341 gctttgacta tcaagtcttc cttctccaac aacaaccaag tcagcatctg aaactttctt
    11401 atcaaagttg attaagtcca agcaggtatc aattccagac acgatacttg cctgagcaaa
    11461 agcacacaaa ccaccagcaa ggcctccacc tgctcctgct cctttaattt ctaatgttgc
    11521 aggtgagaat ttttcataaa aatcttggat cgcctgatct acgactgcaa acatagtcgg
    11581 atgtcgacct ttttgattgc caaaagtata agtcgcacct tgatgaccac ataagggact
    11641 tacgacatct gctaaaatat gaatttgaac accttcagga attttatagc aattttctgt
    11701 tgaaacagaa gctaagttta ataaggattg accggaagca ggcaagacat ttccatccct
    11761 atcataaaat tgataaccta aaccagcagc aatccccagt cctccatcat tactggccgt
    11821 gccaccaaca tcgatataaa tatctttaat ccctttagaa atgagatgga gaatcaactc
    11881 tccaatacca caagtttgga tttgaagtgg atttcgtttc tctagcggaa tttttccaag
    11941 accaaccaag tcagctactt caaatagtgc cagttcccct ttttgaaaat agcgcatggc
    12001 ttctttttgt ccaaaagggt ctgtcacttg gatccatttt tcttttaggt caagagaatg
    12061 tcggatagca tctacagtac cttctccccc atcaccaaca gggcagagga gacattctac
    12121 atctgctatc gattgttgga agcctctttt tattgcttca gctacctgtt gagctgtcaa
    12181 gctttcctta aacgaatccg gtgcaattac aatcttcata ttttccctca ttctaaacag
    12241 tcaatcaaag gaagaacttc taaaaaatcc ctcttgtcaa catgatgtgg tatttctttt
    12301 ttgagcattt ctttggaaca aaaggcgatt cctaactccg ccgacttcaa cattaataga
    12361 ttattgcccc catcaccgat tgccaccgtt ctttctttag aaagttttag tttctttctc
    12421 catttttcca gagtttcttt tttgacctgg ggacttataa tttgtccaac taattttcct
    12481 gttaaaagac cttctttgac ttcaagctgg ttagcagtga aataggcaat accaagggat
    12541 tttgctaatc tctccaacta ttggtgtaaa tccaccagac accagaccaa ctaggatacc
    12601 attcttttgg agaatagaga tgaactctgg gacatttagc gatagatgaa ttgagttgaa
    12661 gacgttatca aagaccaaaa taggaagacc ttccaacaag gacactcttt ttcttaaact
    12721 gctttcaaag accaactctc ctcgcattgc tcgacttgta atctgcgaaa tttctgcctc
    12781 atgacctgcc tctctcccta aaagatcaat cacttcttct aggattaagg ttccatctac
    12841 atccaaaaca cacaagcctt ttacttgaga catcagttct cctctctaaa cagcctaaaa
    12901 atcgtatgaa gtcatcatac gattttatct attaattaac taaactatgg tacaagtcaa
    12961 ggtatgactt gcaggctgta tcccatgaga agtcactctc catagcttgt ttttgtaggt
    13021 ttctccaaat gtctggatgg tttctataca agtccaatgc tgtttggaaa gtccaattta
    13081 accaataagg agatagattg tcaaagctaa agccagtacc gcttccttcg attggattga
    13141 aagcgcgaac tgtatctcgc aagcctccaa cttcatggac caatggcaag gttccataac
    13201 gcatagccat catttgagac aagccacacg gttcaaaacg acttggcatg aggaagaggt
    13261 cacaagcagc gtagatttcc tgagcaagtt tgacatcaaa agtgatattt gttgatagct
    13321 tgtctgggta aatctgagca aaccatgaga aagctccttc aaaggctgga tcgccagttc
    13381 ccaaaagaac aatctgaaca tcttcttgca agatatggtg aagactttcg accaccacat
    13441 caaaaccttt ttgacgtgtc aaacgagaaa caattcccac cagtggaacg tctgctctaa
    13501 caggcaagcc aactctttct tgcaattttg ccttattttt ggctttccca gacaaatctt
    13561 cctgattgaa atgatagtct aaaagagcat ccgtctgagg attataaaga tcagcatcaa
    13621 tcccattcac gataccagat actttaccag actccatttt aagaatctga tccaaattac
    13681 atccaaactg actagtcata atttcatgag catagctagg tgaaacggtt gaaacacggt
    13741 tcgcatagag aatacctgcc ttcatccagt tcagacagtt gttccatcga agggtgccat
    13801 cagcgtaacg ttcaaagcca actccaaaca aatcacccaa cattccttct gaaaattgtc
    13861 cttggaattc taaattatga atggttaaaa ctgtttcaat gtcctcatag gcttgaatcc
    13921 aacggtattt ttccttcaac aagaaaggaa tcatagctgt atggtagtca tgaacatgga
    13981 gaagatcagg aataaagtca atcctttcca tagcctcaat ggcagccagt tggaaaaagg
    14041 caaagcgttc tccgtcatca aaatcaccgt aaacatgacc acggaagaaa taatattgat
    14101 tgtcaataaa gtagaaggtt acaccattta atactgtttt cttaattcca caatactgtc
    14161 tgcgccaacc aacgctcacc tcaaaatgaa gcacatcttc aatctgattt ccaaatttag
    14221 cctctaccat atcatagtag ggtaaaatca ctgcaacttc gtgcccagct tttaccagtg
    14281 attttggaag agcgccaatg acgtctccca aaccacctgt ttttgaaaag ggtgcaccct
    14341 ctgctgctac aaataaaatt ttcatgaatg aatatcctct gttactttag cacctttctt
    14401 aaccacaact ggatgttctg cagttcctcg aatcacaaca ccaggctcaa cttcaacccc
    14461 tttgtccaag atagcatatt cgacctgagc cccttctcca ataacaacac gagggaagag
    14521 caggctatct ttaaccaagc tatccttatg gacatggata ttacgtgata gaacagaatt
    14581 agctacttga ccttcaataa tactaccaga ggcaaactga gaagttctta ccttagatgt
    14641 attagcatag taagttggct cttcgttttt gacctttgta taaatctttt ggtttggtga
    14701 gaaaagagaa tagaattttt gtgattcaag catatcgata ttcgcttgat aataagattt
    14761 aacagagtga atattggcta gatagcccgt gtactcgtag gcgaaagctc cctcttttac
    14821 agccaaatcc cgtaaaacat agcgcaattt ctctggatgt tcttttttag cttcttcttc
    14881 caagtgttca atcaaccaag gtgtatcaac gacaaagata tctgtagaca tattgaacgt
    14941 ttcagctgtt gacttgctat caaagagttt atgagaaaga acatggtctg tttcatctac
    15001 atccaagatt gcatttactt ctgaaatatc tttcttagct agttttttat aaactacagt
    15061 gataggctct tttgttgtac tatgtaggtg gaaaacttgg ttcaaatcaa tgttaataag
    15121 aacatcgcag ttgagggcaa ccgtttggtt tgagccagaa cgtttcaaat aagtaagaag
    15181 ctgttggtag tattcttttc caactgtact actttctaca cgggtattgt aaattcctag
    15241 atagtaatgg ctaagaaagg ttgataagcc ccactcgcgt cctgaacgaa tatggtcaaa
    15301 tactgagctg atattatcct gctggaaaat accaaagaca ctacgaacac ctgcattagc
    15361 aaggcttgaa agtgggaagt caatcaaacg atatttccca ccaaatggca aacttgctac
    15421 tggacggtgg tccgtcaatg tcgacatatt gtgaaaacca actgtatttc ctaaaatggc
    15481 agaatattta tcaatcttca tctgttgcta cccccactac ttcattatat cctacaactt
    15541 gtacttcatc tgttccatca atttcgacac cgtcagaaat aatcgcacct tcaccaataa
    15601 tggcacgttt aatcttagct ccttgaccaa tgatagctcc actcatgata actgaatcaa
    15661 ggacttccgc tccttcgcga acttgcgcgc ctgttgaaag gatagaatgt ttaacagttc
    15721 catcaacgaa acatccgtct acaactaatg agtcttccac atgagcattt gccccgagga
    15781 agtttggtgg tgaaatcaag tttcttgagt aaatcttcca ttgacggtta cgactatcca
    15841 aggcattttc tggagaaata tactccatgt tcgcttccca aagtgactca atagtaccaa
    15901 catctttcca ataaccacta aattcgtaag cataaacact ttcacctgac tcaaggtaat
    15961 ttggaatgac atttttacca aagtctgaca tgccaacctt gctcttttca gcagcgacta
    16021 acatattacg aaggcgttgc caatcaaaaa tgtagattcc catagaagct tttgtagatt
    16081 taggttgagc tggtttttct tcaaattcaa caatacgatt gttagcatct gtgttcatga
    16141 taccaaaacg gcttgcttct ttaagaggga cgtctaaaac tgctactgtc aagctggcat
    16201 tattatcctt atgagactgg agcatatcat catagtccat tttgtagatg tgatccccag
    16261 acaaaatcaa gacatactca ggattgacac tgtcgatata gtcgatattt tggtaaatag
    16321 cgtgactagt cccctcaaac caacgatttc cttcacttgc agaataaggt tgaagaatag
    16381 agacacctga attaataccg tctagtcccc agcttgaacc attcccaata tggttgttga
    16441 gagcaagtgg ttgatactgt gtaacgaccc caacattatg aatccctgag ttggcacagt
    16501 ttgatagggc aaagtcaatg atacggtagc gcccaccaaa ttgcacagct ggttttgcga
    16561 tgctttgagt gagtttaccg agacgagttc cttgcccacc agcaagaatc aaagctaaca
    16621 tttcattttt cattttctac tcctttttgg tttttatttg tgacggtttt agtagatttc
    16681 aagcgacgtt tgattttcca tacacttgct cccatagccg gtagggtaaa ggttaaggtc
    16741 tgctcataat ctttccatag tccttcttgc gtttgaacag tttgattatg ttctttccaa
    16801 acgcctcccc actcttccaa ctcagtattc catacttctt cgtaaattcc tgcaacgggt
    16861 agtccgattg taaaatcttt ccgctcaaca ggtaccatgt taaagataca gactaacatt
    16921 tctccctttt tacccttacg aataaaggaa agaacactct ggtctcgatt atccgcatca
    16981 atgacttcaa taccatcata gctggtatcg atttcccaca gacagcgatg atctttgtaa
    17041 aactggttta gctgagaagt gaaatacttc atcttagcat tcattgggtc ttctaggtta
    17101 gaccattcca actgttcttc agatttccat tctaggaatt gaccgtattc gctacccatg
    17161 aagagcaatt tcttaccagg gtgacaaatt tggtacgtat agagattgcg caagcctgcg
    17221 aattgattgt aacgatctcc ccacatctta tgcatcatac tcttcttgcc atgaaccact
    17281 tcatcgtgcg agaatggcaa gagataattc tccttgaaaa catacataaa gctgaaagtc
    17341 accaggttaa agtcatattt acgataaatc ggatcttctt cgtagaaacg gaggatatca
    17401 ttcatccagc ccatgttcca tttgtagtca aatcctagac caccaatctc tttcattccc
    17461 gtaatcttgg ttgcagacga actttcttct gcaatcatca tcacatctgg atattctaac
    17521 ttaataactt cattcaagcg ttgaaggaaa taataacctt catagttgag atttccgcca
    17581 tctttattag gtgtccatgg agcatcatca tagtccaaat agagcatgtt gctaacagca
    17641 tccacacgaa taccatccaa atgatagata tcaatccaat gcttaatgca agaaattaag
    17701 aaggactgga cttcattttt tccaaggtca aaattaaggg caccccaacc atggttatga
    17761 gccttattat ggtcttggta ttcaaaagtc ggtgtcccat cataataggc taaggcatca
    17821 tcattgatgg taaagtgacc tggtacccag tccacaataa ccccaatatt atgggtatga
    17881 cactcctcga caaaatcttg aaactcctct ggtctaccat aggcatgctc taaagcgaag
    17941 taacccataa gctggtaccc ccaactcaaa cctagtgggt gggacatcaa gggcataaac
    18001 tcaatatgag tatagttcat ctcaactagg taaggaatga gttcatcttt caattgggca
    18061 aaactataag gactgccatc aggatttctc ttccaagagc cagcatgaac ctcgtaaata
    18121 ttgacaggac gttcagcaaa gccccaacgt tttcttcgtg ccagccaaag tccatccctc
    18181 catttcttat caggaagctc tgttacgatt gcccctgttc ctggacgagc ctcatacctg
    18241 acagcaaaag ggtcaatctt catcagttga tgaccatttt gacgtgtgac atgatatttg
    18301 taaatatgcc cttcttgagc catattggta aagacttccc agaccccaaa gtcatttctt
    18361 accattggaa tctgattttc aatccaattg gtaaaatcac caaccaagtg aacagcctga
    18421 gcattaggtg cccaaacacg gaaggtatag ccatactctc catttagttc ttccctatgt
    18481 gctcctagat aatgttggag ataaaaattt tcacccgtca taaaggtttt taatgcttct
    18541 ctattatcca tatactccct ttctcctgta agcgttttct atgtttttat tatactacct
    18601 ttttagagaa gattcaagta aattactata cttctttaat tattttgaaa atctacaaca
    18661 agttcactta ctcgttcaat tgtaaatcaa tattttttca aaaaattgcg aaaacacctt
    18721 tctttttcta ctatagtgaa atgaaataaa acatgcgcaa atcgattaag gaatttaatc
    18781 taatttctaa caatgtctta gaaatcaaag
//
LOCUS       DAVBEM010000045        18504 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVBEM010000045 DAVBEM010000000
VERSION     DAVBEM010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18504
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.045"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            16..86
                     /locus_tag="VQ548_001618"
     tRNA            16..86
                     /locus_tag="VQ548_001618"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48..50,aa:Gly,seq:tcc)
     gene            122..195
                     /locus_tag="VQ548_001619"
     tRNA            122..195
                     /locus_tag="VQ548_001619"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:156..158,aa:Ile,seq:gat)
     gene            202..289
                     /locus_tag="VQ548_001620"
     tRNA            202..289
                     /locus_tag="VQ548_001620"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:236..238,aa:Ser,seq:gct)
     gene            complement(423..860)
                     /locus_tag="VQ548_001621"
     CDS             complement(423..860)
                     /locus_tag="VQ548_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET2654437.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKKEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYSNAKLEA
                     TNNLIKLIKCNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(1111..2046)
                     /locus_tag="VQ548_001622"
     CDS             complement(1111..2046)
                     /locus_tag="VQ548_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HET2654438.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(2043..2903)
                     /locus_tag="VQ548_001623"
     CDS             complement(2043..2903)
                     /locus_tag="VQ548_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET2654439.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFYYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            3011..5173
                     /locus_tag="VQ548_001624"
     CDS             3011..5173
                     /locus_tag="VQ548_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HET2654440.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATITSYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIATLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIILSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYFYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            5265..6524
                     /locus_tag="VQ548_001625"
     CDS             5265..6524
                     /locus_tag="VQ548_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2654441.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADDTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRSE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            6538..7404
                     /locus_tag="VQ548_001626"
     CDS             6538..7404
                     /locus_tag="VQ548_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2654442.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            7418..8251
                     /locus_tag="VQ548_001627"
     CDS             7418..8251
                     /locus_tag="VQ548_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2654443.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKSTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIIAGISNGAV
                     K"
     gene            8252..8332
                     /locus_tag="VQ548_001628"
                     /pseudo
     CDS             8252..8332
                     /locus_tag="VQ548_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            8470..9912
                     /gene="gtfA"
                     /locus_tag="VQ548_001629"
     CDS             8470..9912
                     /gene="gtfA"
                     /locus_tag="VQ548_001629"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HET2654444.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTEILPEIHEHYSIQFKIADHDYYVYDFTLPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAREVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVSF"
     gene            10050..11243
                     /locus_tag="VQ548_001630"
     CDS             10050..11243
                     /locus_tag="VQ548_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HET2654445.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11930..13909
                     /locus_tag="VQ548_001631"
     CDS             11930..13909
                     /locus_tag="VQ548_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2654446.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13976..15472
                     /locus_tag="VQ548_001632"
     CDS             13976..15472
                     /locus_tag="VQ548_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2654447.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            15472..16398
                     /locus_tag="VQ548_001633"
     CDS             15472..16398
                     /locus_tag="VQ548_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2654448.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSIRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            16407..17474
                     /locus_tag="VQ548_001634"
     CDS             16407..17474
                     /locus_tag="VQ548_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2654449.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            17485..18411
                     /locus_tag="VQ548_001635"
     CDS             17485..18411
                     /locus_tag="VQ548_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2654450.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
BASE COUNT         5422 a         3292 c         3873 g         5917 t
ORIGIN      
        1 attgatagta tttatgcggg tgtagtttag tggtaaaact acagccttcc aagctgttgt
       61 cgcgagttcg attctcgtca cccgctttga actttgttca aattaccaag ttttttaact
      121 tgggcgcgta gctcaggtgg ttagagcgca cgcctgataa gcgtgaggtc ggtggttcga
      181 gtccactcgt gcccattaat tggagaatta ctcaagaggc tgaagaggac ggtttgctaa
      241 atcgttaggt cgggtaactg gcgcaagggt tcgaatccct tattctccgt tttaatgaga
      301 gtttgtaact ctctttttta tttttagaga caataaagct tcagatccgt aaaacttaat
      361 tgaattacta atctgaagtt atttttatgg ctctttgtca actgtagtgg gttgaagaaa
      421 agctaagctc gagaaaggac aaatttcgtc ctttcttttt tgatgttcaa agcgataaaa
      481 atccgttttt taaagttttc aaagtttcga aaaccaaagg cattgcactt gataagtttg
      541 atgagattat tggtcgcttc cagtttggcg ttagaatagt gtagttgaag ggcgttgaca
      601 atcttttctt tatctttgag gaaggtttta aagacagtct gaaaaatagg atgaacctgc
      661 ttaagattgt cctcaataag tccgaaaaat ttctctggtt cctttttctt cattagactt
      721 ccacaatcag ggcaagatgg agcctcataa tccagcttag cgataatttc tttgtgggta
      781 tccatattga tgatatctag aatcttgatg tttgggtctt taatgtctag taattttgtg
      841 ataaaatgta attgttccat atgattcttt ctaatgagtt gttttgtcgc ttttcattat
      901 aggtcatatg ggactttttt tctacacaaa ataggctcca taatatccat agggaattta
      961 cccactacaa atattataga gcccgtttta atgagagttt gtaactctct tttttgtttt
     1021 tagagacaat aaaacttcag atccgtaaaa cttaattgaa ttactaatct gaagttattt
     1081 ttatatcgtt tatattataa ttgtgttatt ttacttccaa ctattgagag aaatttcgcc
     1141 actatttagc cagatttctt ttccgttatc acattgaact aaaagttttc cattttctga
     1201 gatgtcttta gcaagtccct tgtagtcttt ttgctctagt gtgaaagtga cttcttttcc
     1261 tagaatgaat gactgttttt tgtataggta taatagctct tctgctggtg tttcgaagaa
     1321 agcacgccag atttctatga tcaattcatt ccttgttata ggagctgtag ctttaaataa
     1381 gctggcagct ttttctttta attcctgagg gaagtcttta atagtgaaat tgatacctac
     1441 tccaataatg atatctgtga ctaagccagt ttctacagag gtcattgctt cagtaaggat
     1501 tcctccaatt ttatgattgt ttagatagat atcattgacc cattttatgt cgacatctat
     1561 taaagttagg ttcttaatgg ctttgtagac agctccagct acaagtagtg tgtaggatgg
     1621 taatttgtca taggggagat ttggtttaag atggagtgtc atataaatac caccttgtgg
     1681 tgagtagaag gaacgttgaa aacggcctcg gcctgctgtt tgataggaag ctagatagag
     1741 ggtatttgct tcatggccta aatcaattgc ttcttttgca tctagttgtg ttgattttgt
     1801 ttcgggttta aagctgactt taattggaag attttcttct agaatctctg gaagaataag
     1861 gtcaccattc atcagtttat atcctctatt tttgatacta tcaatttcaa tgccttcttg
     1921 ttctagtcgc ttgatggctt tccaaattgc tgttcggctt agggatagtt tttctgcgat
     1981 tttttctccg ctgatatagt cggtttcttt agataggatt tggtagacag cttggtagga
     2041 tttcataatg ttgcctttct cactagttgg tattgagagt attcttttct tgtatgactt
     2101 ggagtctgat taaagtattg tttataagct ttcgaaaaat ggagtggatc tgaaaaacct
     2161 accgagtatg caattacctt gatggactct tgggtatttt cgagaagttg tctagctcgg
     2221 tgcattcgaa cgtagagtag gtattctttg ggtgataagg tattaaattc tttgaatacg
     2281 cttgataagt agcttctgtg aacggatagt tcttttgcta aatcttgaat tgtaagtgat
     2341 tgaggatagt ggctatcaat taatcgtttg cattcaagat agagttggtg ggttgatgaa
     2401 atattctttt ttttctgatt gggagcaata gttcccagat gaaacatcag ttcatgaagt
     2461 tgtcccatga tatggagttg agctaattca cttgattttg taatctgagc gaagcggaca
     2521 atgtctgaga tgagttttgc agtagtctgg gtatgacaag tttcagattg gatgagatag
     2581 gattgatcag aaatttgaga aagagcaaaa taatcagggg atttccctcc agtgattcct
     2641 aaccagtagt aggcccaagg ttctttacta tctgcttgat aaaaggttag ttcctctggt
     2701 tttaatagaa agaaatctcc ttcttttaaa tcaacaattt tacccttgta ataaaatttt
     2761 ccttgtcctt tagtaatgta atgtagaacg tatgtatcac gaatggctgg accaaaagag
     2821 taattaggtg tgcattcctc atatccataa aagcttaggg caaggtcgat tgttccagtc
     2881 tggtattctg aaaaaactaa catgtgctac ctcctaccta acattttacc atattcttga
     2941 gacatttttc tattttggaa agcgatttca ggtgataaaa tataatcaat aaagtgatga
     3001 ggtgaagtaa atgggagtta ggatagagaa taatctattt tatgttgaga gtaaaaatct
     3061 aagtttgatt attgaaaatc gaaatggcta cttacttttg aaacatttag gaaagactat
     3121 taagaactat aaaggttcca atagtgttta tgaacgagac catgcctttt caggaaatcc
     3181 aacggctact aatcgaacct ttagtttaga tactcagcga cagatttttg gacaacatgg
     3241 cttaggagat tttaggaaac caactataca ggttcagcat agtgtaactg aagtaacaga
     3301 ctttcgattt gtagaagcaa agattttaaa aggtcagaat ggtccacagg gcttaccttc
     3361 tccacatagc atggacgata cagagactct tgtcttaatg ttagaagatt ctaaggctca
     3421 acttagtctg actttgtatt atactacttt taataatgat gcgactatta ctagctacag
     3481 taaattagat aataatagta atcaggaagt tgtcatccat aaagattttt cttttatggc
     3541 tgattttcca gctgcagatt acgaaatagc aactctgcag ggtgcttatg ctcgtgaaaa
     3601 gactgttaga cgtcaacagg tagaacaagg aatcttttcg attagttcaa accgaggtgc
     3661 ttctggtcat gctcaaacac cagctcttct actatgcgaa caaggagtca cagaggatgc
     3721 tgggaatgtg tttgctattc aactaatgta tagtggcaac tttgaagctt ttgttcaaaa
     3781 aaatcaattg aatgaagttc gggtggctat tggcattaat ccagaaaact tttcttggaa
     3841 gttagcccct gaggaatact ttgaaacacc ggtagcttta gtgactcatt cagatcaggg
     3901 attaactggt attagtcatg aaagtcagaa ttttgtactg aagcacatta ttctaagtga
     3961 attttctaaa aaagaacgtc caattctaat caataactgg gaagctactt actttgactt
     4021 tcagagagaa aaactgttag agttagcaga tgaagctaag aaagttggca ttgaactttt
     4081 tgtattagat gatggttggt ttggcaatcg ttttgatgat aatcgtgctt taggtgattg
     4141 ggttgttaat gaggaaaaac tgggtggaag tctagaaagt ctgatttcag ctatccatga
     4201 aagaggtttg cagtttggac tttggttaga acccgaaatg atttctgtag atagtgattt
     4261 gtatcgtcaa caccctgact gggctattca ggttcctgac tatgagcata cttattctcg
     4321 gaatcaatta gtacttaatc ttgccaatcc tcaggtagta gaatacttga aaagtgtctt
     4381 agatcaactc ctatcttatc atgagattga ttacattaaa tgggatatga accgcaatat
     4441 cactaagcta gggaatggat taacttatct agagacacag atgcaatctc atcagtacat
     4501 gctggggctt tatgaactcg tttcttatct gacagagaag cacagccata ttctctttga
     4561 gtcctgctct ggtggtggtg gacgaaatga tcttggtatg atacgctatt tcccacaagt
     4621 ctgggctagt gataatactg atgccattgc acgtttacca attcaatacg gttcatccta
     4681 tttctatcca accatttcta tgggggctca tgtgtcagca gtaccgaatc atcagatggg
     4741 acgaatgaca ccattagaaa cacgtggcca tgtagcaatg atgggaaatt tgggctatga
     4801 gcttgatttg acaaatttat cagatgaaga gaaagctacg attgctaatc aggtgaactt
     4861 gtataaagaa ttacgaccag tagttcagtt aggacagcag tatagactaa ttaatcctga
     4921 tactgcatcc aatgaagcag ctgtacaatt taattacgga aatcaaacga ttgtaaccta
     4981 cgttcgcgtt ttatctgttg tagagaccat ggaaacaact ttaaaattaa aagatttgga
     5041 tgaagaggga ctatataaat tacaggaaaa tggcgaagtt tactcaggtg cagaactaat
     5101 gtatgcgggc ttaactgtta tcttatccca aggagatttt ttgagtagac agtatatttt
     5161 tagaaaacta tgatatgtac tgaccccaaa agttagattt attctatcta acttttgaag
     5221 tgcagtttga taagggtgta taaatttata aaggaggctt tctaatggaa tggtataaaa
     5281 aaatcggact tcttgcaact acaggtttag ctttgtttgg gctcggtgct tgctccaact
     5341 atggtaaatc tgcggatgac acagtgacca tcgagtattt caaccagaaa aaagaaatga
     5401 ccaaaacctt ggaagaaatc actcgtgatt ttgagaagga aaaccctaag ataaaggtca
     5461 aagtcgtcaa tgtaccaaat gctggtgaag tattgaagac acgcgttctc gcaggagatg
     5521 tgcctgatgt ggtcaatatt tacccacagt ccatcgaact gcaagaatgg gcaaaagcag
     5581 gtgtctttga agatttgagt aacaaagact acctgaaacg cgtgaaaaat ggctacgctg
     5641 aaaaatatgc tgtaaacgaa aaagtttaca acgttccttt tacagctaat gcttatggaa
     5701 tttactacaa caaagataaa ttcgaagaac tgggcttgaa ggttcctgaa acctgggatg
     5761 aatttgaaca gttagtcaaa gatatcgttg ctaaaggaca aacaccattt ggaattgcag
     5821 gtgcagatgc ttggacactc aatggttaca atcaattagc ctttgcgaca gcaacaggtg
     5881 gaggaaaaga agcaaatcaa taccttcgtt attctcaacc aaatgctatt aaattgtcgg
     5941 atccgattat gaaagatgat atcaaggtca tggacatcct tcgcattaat ggctctaagc
     6001 aaaagaactg ggaaggtgct ggctataccg atgttatcgg agccttcgca cgtggggatg
     6061 tcctcatgac accaaatggg tcttgggcga tcacagcgat taatgaacaa aaaccgaact
     6121 ttaagattgg aaccttcatg attccaggaa aagaaaaagg acaaagctta accgttggtg
     6181 cgggagactt ggcatggtct atctcagcca ccaccaaaca tccaaaagaa gccaatgcct
     6241 ttgtggaata tatgacccgt tcagaagtca tgcaaaaata ctacgatgtg gacggatctc
     6301 caacagcgat cgaaggggtc aaacaagcag gagaagattc accgcttgct ggtatgaccg
     6361 aatatgcctt tacggatcgt cacttggtct ggttgcaaca atactggacc agtgaagcag
     6421 acttccatac cttgaccatg aactatgtct tgaccggtga taaacaaggc atggtcaatg
     6481 atttgaatgc cttctttaac ccgatgaaag cggatgtgga ttaggagtag agagactatg
     6541 aaaaaagtat tacaaaaata ttgggcatgg gcttttgtgg tcatccccct cttgttacaa
     6601 gcaattttct tctatgtgcc gatgtttcaa ggagcctttt acagttttac caactggaca
     6661 ggattgactt acaactacaa atttgtcggc ttaaacaact ttaagctcct cttcatggat
     6721 ccaaaattca tgaatgcgat tggctttacc gcaatcatta cgattgccat ggtggttggt
     6781 gagattgcac tcgggatctt cattgcgcgt gtcttgaact ctaaaatcaa aggccaaacc
     6841 ttcttccgtg cttggttctt cttcccagct gttttatctg gtttgacagt ggctttgatc
     6901 ttcaagcaag tcttcaacta cggtcttcca gcgattggga atgcccttca tattgaattt
     6961 ctccaaacca gtcttttagg gactaagtgg ggagcaatct ttgcggctgt ctttgtcctt
     7021 ctttggcaag gggtggctat gcccatcatc atcttcctag ctggtttgca atctattcca
     7081 actgagatta cagaggcagc aaggattgat ggtgcgacta gcaagcaagt tttctggaac
     7141 attgaattgc cttacttgct accaagtgtc tctatagtct ttatcctagc cctaaaaggt
     7201 gggctgactg cctttgacca agtctttgcc atgaccggtg gtggtccaaa caatgccaca
     7261 acctcacttg ggctcttggt ttataactat gcctttaaaa acaaccaatt cggttatgcc
     7321 aatgccattg ccgtaatctt gttcttctta attgtagtga tttcgatcat ccaattgaga
     7381 gtatctaaga aatttgaaat ttaagaggag aagcatgatg aaacaagatg aaagaaaagc
     7441 cctgattggc aaatacattc tattgattct aggatcggtt ctgattttag tgccgctcct
     7501 tgctaccctc tttagttcct tcaaatccac taaggatatt gtagataatt tctttggctt
     7561 tccaaccaac ttcacatggg acaactttag ccgtctctta gctgatggga ttggaggcta
     7621 ttattggaac tctgtcgtca tcactgtctt gtctttactt gcagtaatga tctttatccc
     7681 tatggcagcc tactccatcg ctcgcaatat gagtaaaaga aaagccttta ccatcatgta
     7741 taccctctta atcctcggaa tcttcgtacc tttccaagtc atcatgattc cgattacggt
     7801 tatgatgagt aaactcggtt tggctaatac ctttggtttg atcttgctct acttgaccta
     7861 tgcgattcca cagaccctct ttctctatgt tggctatatc aaaatctcga ttccagaaag
     7921 tctggatgaa gcagcagaga tcgatggggc taatcaattt acaacctatt tccgcatcat
     7981 cttcccaatg atgaaaccga tgcatgcgac aaccatgatc atcaatgccc tttggttctg
     8041 gaatgacttc atgttgccac tccttgtctt gaaccgggat tccaaaatgt ggactctgcc
     8101 tttgttccaa tacaactacg caggccaata tttcaacgac tacggaccaa gctttgcctc
     8161 ttacgtggtc ggcattatca gtatcaccat tgtctatctc ttcttccaac gccatatcat
     8221 cgcaggaata agcaacgggg cagtgaagta atactcaatg aaaatcaaag agcaaactag
     8281 gaagctagcc gcaggttgct caaaacactg ttttgaggtt gtggatgaaa ctgacgaagt
     8341 cagtaaccat atctacggta aggcgacact gacgtggttt gaagagattt tcgaagagta
     8401 taacatgaat ttgatttacg aagccagatc atatgagact tggcttcaat tagaaaaagg
     8461 agagtaatga tgccaattca aaataaaacc atgttgatta cctattctga tagccttgga
     8521 aataatctta aagacttata tgataatttg gaagagcatt ttggagatgc tattggagga
     8581 gttcaccttt taccattttt cccatcaaca ggtgatcgtg gatttgcgcc agttgactac
     8641 gacgaagtgg actcagcttt tggtgattgg gaggatgtta agcgtttagg tgagaaatat
     8701 tatcttatgt ttgattttat gattaatcat atttctcgtc aatccaagta ttataaggac
     8761 tatcaagaaa aacatgaagc cagtgaattt aaagatctct ttttaaactg ggataagttt
     8821 tggccagaaa accgtccgac acagtctgat gtagatttaa tttacaagcg taaggatcgt
     8881 gcaccaaagc aagagattgt gtttgaagat ggttcagtgg aacatttgtg gaataccttt
     8941 ggtgaggagc agattgatct tgatgtgacc aaagaagtaa ctatggaatt tatccgtaag
     9001 accattcagc acttggcaag taatgggtgt gatttgattc gtctagatgc ctttgcttat
     9061 gcagtgaaga aattggatac taatgatttc tttgtggaac cagatatttg ggatttattg
     9121 gacaaagttc gagatatcgc tgctgagtat gggacagaga ttttacctga gattcatgaa
     9181 cactattcga ttcagtttaa aatagcagac catgattact atgtttatga ttttactctt
     9241 ccaatggtga cactttatac tctttacagt tccagaacag agcgtttggc taagtggttg
     9301 aagatgagcc cgatgaagca atttacgacg ctagataccc atgatgggat tggagtagta
     9361 gatgtcaagg atatcctgac cgatgaggag attgactatg cttcaaatga actctataag
     9421 gttggagcca atgtcaaacg taagtactct agtgccgagt ataacaactt agatatctac
     9481 caaatcaatt caacctacta ttcagcgctt ggagatgatg atgtcaagta ttttctcgct
     9541 cgtctaattc aagcttttgc cccaggtatt cctcaggttt actatgtggg tctattagca
     9601 ggcaagaatg acttgaaatt attagaagaa actaaagaag gtcgaaatat taatcgtcat
     9661 tactatagca acgaggaaat agcaagagaa gtgcaacgac ctgttgtgaa ggcccttctc
     9721 aatctatttt ctttccgtaa ccgttcagaa gcctttgatc tagaagggac tactgagata
     9781 gagacaccaa cagctcacag cattgtaatc aaacgtcaaa ataaagataa gtccgtaaca
     9841 gcagtagcag aaattgattt gcaaaatcag acttatcggg taattgagaa tggagttgaa
     9901 gtatcatttt gaagccttga tatggtggat aaaatagggt ttttattttg gaaaacgttt
     9961 cctttgtttt caaattgcta aaaaagtggt acaatatagg atagcttact attatctgaa
    10021 tcagctgatt tggagagaaa ggattcattt tgaaatcaat aggctttatt gaaaagctga
    10081 aggggttgtc tagtaaagag ctgattttat tgggaattat cctaagtatc tttttaccct
    10141 tttatctttt tgtagttgta ctctgtttat atattatcag tttgattttt acaggagaca
    10201 tgaaaagtat tcttcagaaa atgggggagc atccgatgct gcttcttttt cttagctata
    10261 gtactgttat atccattctt gcacaaaatt ggatgggtct tgtggcttca gtaggaatgt
    10321 ttctatttac tattttcttt ttgcactatc agtcgatttt atcccataaa ttctttcgat
    10381 tgattttgca gttcgtcttg tttggtagtg tcttgtcagc tgcttttgcc agtttagaac
    10441 atttccaaat tgtgaagaaa tttaactatg cttttctttc acccaatatg caggtgtggc
    10501 atcagaaccg ggcagaagtg accttcttta atcctaatta ttatggaatt atttgttgtt
    10561 tctgtattat gattgctttc tatctgttta caacgaccaa gttgaattgg ttgaaagtat
    10621 tctgtgtgat tgcaggcttt gttaatctct ttggtttgaa ctttactcaa aatcgaactg
    10681 cctttcctgc tattatcgct ggagcaatta tctatctctt tacgactatt aaaaactgga
    10741 aggccttttg gcttagtatt ggggtcttcg cgattggttt gagtttcctc ttttctagtg
    10801 atttgggagt tcgaatgggt actttagact cttctatgga agaacgcatt tctatctggg
    10861 atgctgggat ggccttgttt aagcaaaatc ctttttgggg tgaagggcca ttgacctata
    10921 tgcactctta tcctcggata catgctcctt atcatgaaca tgcccacagt ctttatattg
    10981 atacgattct gagttacgga attgtgggta ccattttatt agttttgtct tctgttgctc
    11041 ctgttcgctt gatgatggat atgagtcagg agtcggggaa acgtccgatt atcggccttt
    11101 atctatcttt ccttacagtg gttgctgtgc acggaatttt tgacttggct ctcttctgga
    11161 ttcagtcagg ctttattttc ttgctagtta tgtgcagtat tccattggag catcgaatgt
    11221 tggtatcgga catgacggat taagttttat aagtttgaaa tcttctacct tgggtaggag
    11281 atttttttat acgatgggca tgtcgtgcat ctgaggtgta agtcctctgt agggatccac
    11341 taccggtgaa tacaatagcg ctccccaagc ctgactatcg tgaggtagcg gattaaaatg
    11401 gtctggggat agatcgtttt aagtctgacg caggaaataa gaattgtcag agaaagcaat
    11461 agtgaaatcg taggctatga atagaaacgt gatagcgagg agcatatagt ggataaggta
    11521 gcgagaaatt ttaaagtata aaagatagtc ttaatctata tatgtaaatc acaaaagtaa
    11581 ttgaattcgg aataaggttg gtgtgaaaag acatagtaaa ctgaatcttg aatactagaa
    11641 tgatacttct acaatattgt tataatttaa tttgaattcc aaaatcacat tgttccgtcc
    11701 gtatttcatt ttactgtatg tcttcctaaa ctccaaagtt tctgcgtcaa atttcctatt
    11761 ttcactgtag tctttgacac ttcgaacgac aatttgaatc atatattcaa aaaaaaatga
    11821 aaaatttgtg ccaacaagcc taaatattct gaaaatttgt ttgattttta atggataatg
    11881 tgatataatg gttgtcaatc tataattcac ataaacagag gagtagaaaa tgaaaaaaaa
    11941 tcgtgtattt gctacagcag gtcttgtttt attagcagca ggtgtacttg cagcatgcag
    12001 ttcttcaaaa tcatctgatt catcagcccc taaagcttat ggctatgttt atacagcaga
    12061 cccagaaacc ttggactacc tgatttcaag taaaaatagt acaacagtag tgacttcaaa
    12121 tgggattgat ggtttattca ctaacgataa ttacggtaat cttgctcctg cagttgcaga
    12181 ggattgggaa gtctctaagg atggtttgac ctacacttat aagattcgta aaggggttaa
    12241 atggtttacc tctgatggag aagaatatgc agaggtgacg gctaaagatt tcgtgaacgg
    12301 tttaaaacac gcagcagata aaaaatcaga agctatgtat ttagctgaaa attcggttaa
    12361 aggcttggca gattatctat caggaacttc aacagatttt tcaacagttg gtgtcaaggc
    12421 ggttgatgat tatacgttac aatacacttt gaaccagcct gaaccgttct ggaactctaa
    12481 gttgacctat tctattttct ggcctctgaa tgaagaattc gaaacatcaa aaggaagcga
    12541 ttttgctaaa ccaacagatc cgacatcctt gctttataat ggtccattct tgttgaaagg
    12601 gttgactgca aaatcttctg tagagtttgt aaaaaatgag caatattggg ataaagaaaa
    12661 tgtccaccta gatactatca atctagctta ctatgatgga tcagatcagg agtcgctaga
    12721 gcgtaacttc actagtggag cttatagtta tgcccgtctt taccctacca gctccaacta
    12781 ttctaaggtt gcagaagaat acaaggacaa tatctattac acacaatcag gctctgggat
    12841 tgctggtctg ggtgtgaata ttgatcgcca aagttacaac tatacttcta aaactacaga
    12901 ttcagagaaa gtagctacta agaaggcatt gcttaacaaa gatttccgtc aagccttgaa
    12961 ttttgctctt gatcgctcag cttactcagc tcaaatcaat ggtaaagatg gagcagcttt
    13021 agcagttcgt aatttatttg taaaaccaga ctttgtttca gctggtgaga agacctttgg
    13081 tgatttagtc gctgctcaac ttcctgctta tggtgatgag tggaaaggtg tgaatttagc
    13141 tgatgggcag gatggtttat tcaatgctga caaggccaag gcagagtttg cgaaagctaa
    13201 gaaagcttta gaagcagacg gcgttcagtt tcctattcat ctggacgttc cagtagacca
    13261 agcatcaaaa aactacatat ctcgtattca gtcctttaaa caatctgtag aaacagttct
    13321 tggtgttgaa aatgtcgttg ttgatattca acaaatgaca agtgatgaat tccttaatat
    13381 tacttactat gctgccaatg cttcatctga ggattgggat gtatcgggag gagtttcatg
    13441 ggggccagac tatcaagacc catctactta cctggatatt ttaaaaacaa ctagcagtga
    13501 aactacaaaa acatatttag gatttgataa tccaaatagc ccttcagtag ttcaagttgg
    13561 tttgaaagaa tacgataaat tagttgatga agctgccaaa gagacaagcg acttgaatgt
    13621 ccgttatgaa aaatatgcag cggctcaagc atggttgaca gatagttcac tctttattcc
    13681 tgctatggct tcttctggtg cagcaccagt gctttcacga attgttccat ttactggagc
    13741 ttctgcgcaa acaggctcta aggggtcaga tgtttacttc aaatatttga aattacaaga
    13801 taaagtggtg actaaggaag agtatgaaaa agctcgtgaa aaatggttga aagaaaaagc
    13861 tgaatcaaat gagaaagctc aaaaagaatt ggcaagtcat gtgaagtaaa taatttctaa
    13921 tagaactttc tctccatgag gagaaggttc ttttgggatt tttaaaggaa ataatatgaa
    13981 aaaatatatt tttatgcgtg ttttgcggtc attggtttcg attttcttag taacgacttt
    14041 gacctacacg attatctata ccttggttcc tcgaaaattg attttcaagc aggatcctaa
    14101 ctataataaa attgcaacaa cggctgataa acgtgataac tatgaaaata ctgtgtttga
    14161 gcgtatgggc tacattgagt attacgatac taaagagttg caagaaaagg caagtagcat
    14221 ggattcttct gtaacagtag aagcaaatgc gaccaataaa gctatttatg aaaagtacat
    14281 caatcaatta ggtcatggtt ggactttggg agaatttact gaaagtggtc aattctatgc
    14341 tactcgtgaa attccaattt ttgaacgtgt ttttcacttc tatgctaact tgattgacat
    14401 tgaccataca aataaaatcc aagaccctga aaatccagac ttgaaacgct accttcgttt
    14461 tgaaaatgat ccagctatcg gatggtcatt ggtcggttca ggaactaaac ataaatatct
    14521 cttgtacttt aacagtcagt tcccatttgt tcatcaaaac tttgtgaact tgaatttagg
    14581 tgactcttac ccaacctatg ctaatacacc agttcttcag gttattactc aaggtcaagg
    14641 acaaaccaaa actgcccaag ttcagttccc aacaggtaag aaaacgtctt ctgtaaatat
    14701 ttactcaaga acctacaagt cacctagtca ggctgactct cgtgaagtag ctagctatgg
    14761 gaaagatgat ccttatacag cgactgaaag taattaccaa tatccatcta tgattgtcag
    14821 ctctgctatt actggtttga ttggtttggt tcttgcctat gctcttgccg tgccacttgg
    14881 ttcagccatg gctcgtttca agaacacttg gattgatagc ctctcaacag gggctttgac
    14941 cttcttgctt gctcttccaa cgattgcctt ggtttacatc gttcgattga ttggatcatc
    15001 tattgccctt ccagattcat tccctatctt gggagctgga gattggcgtt cttacgtttt
    15061 accagcagtc atccttggtt tgttgggtgc tcctggtaca gccatttgga ttcgtcgtta
    15121 catgattgac ttgcaatctc aagactttgt tcgtttcgct cgtgcaaaag gtttgtctga
    15181 aaaagaaatt tcaaacaaac acatctttaa aaatgccatg gttccgctgg tttcaggaat
    15241 tcctggtgcc atcattgggg ttatcggtgg tgcaaccctt actgaaacag tcttcgcctt
    15301 cccaggtatg ggtaaaatgt tgattgactc tgtaaaagca tctaataact ctatggtcgt
    15361 tggtcttgtc ttcatcttta catgtatttc tatcttctca cgtcttttgg gagatatttg
    15421 gatgactatt attgacccac gtattaaatt gactgagaaa ggaggcaaat aatgtctaca
    15481 atcgataaag aaaaatttca gtttgtaaaa cgtgacgatt ttgcctctga aactattgat
    15541 gcgccagcat attcttactg gaaatcagtg tttaaacaat ttatgaagaa aaaatcaact
    15601 gtagtcatgt tgggaatctt ggtagccatc attttgataa gtttcatcta cccaatgttt
    15661 tctaagtttg atttcaatga tgtcagcaag gtaaacgact ttagtattcg ttatatcaag
    15721 ccaaatgcgg agcattggtt cggtactgac agtaacggta aatcgctctt tgacggtgtc
    15781 tggttcggag ctcgtaactc catcctcatt tctgtgattg cgacagtgat taacttggtt
    15841 atcggtgttt ttgtcggtgg tatttggggt atttcaaaat cagttgaccg tgtcatgatg
    15901 gaagtttaca acgtcatctc aaacatccca cctcttttga ttgttattgt cttgacttac
    15961 tcaatcggag ctggattctg gaatctgatt tttgccatga gcgtaacaac atggattggt
    16021 atcgccttca tgatccgtgt gcaaatcttg cgctatcgtg acttggaata caacttggca
    16081 tcacgtactt tgggaacacc aaccttgaag attgttgcca aaaatatcat gcctcaattg
    16141 gtatctgtta ttgtgacaac catgactcaa atgcttccaa gctttatctc atacgaagcc
    16201 ttcttgtctt tcttcggtct tggattaccg attacagtgc caagtttggg tcgtttgatt
    16261 tcggattatt cacaaaacgt aacaaccaat gcttacttgt tctggattcc attgacaacc
    16321 cttgtcttgg tatccttgtc ccttttcgta gttggtcaaa acttagcgga tgctagtgat
    16381 ccacgtacac atagatagga gtagaaatga caaaagaaaa aaatgtaatt ttgactgctc
    16441 gcgatattgt cgtggaattt gacgttcgtg acaaagtatt gacagccatt cgcggcgttt
    16501 cccttgaact cgttgaagga gaagtattag ccttggtagg tgagtcagga tcaggtaaat
    16561 ctgttttgac aaagaccttc acaggtatgc tcgaagaaaa tggtcgcatt gcccaaggta
    16621 gtattgacta ccgtggtcag gatttgacag ctttatcttc tcacaaggat tgggaacaaa
    16681 ttcgtggtgc taagattgcg actatcttcc aggacccaat gactagtttg gaccccatta
    16741 aaacaattgg tagtcagatt acagaagtta ttgtaaaaca ccaaggaaaa acagctaaag
    16801 aagcgaaaga attggccatt gactacatga ataaggttgg cattccagac gcagatagac
    16861 gttttaatga atacccattc caatattctg gaggaatgcg tcaacgtatc gttattgcta
    16921 ttgcccttgc ctgccgacct gatgtcttga tctgtgatga gccaacaact gccttggatg
    16981 taactattca agctcagatt attgatttgc taaaatcttt acaaaacgag tatcatttca
    17041 caacaatctt tattacccac gaccttggtg tggtggcaag tattgcggat aaggtagcgg
    17101 ttatgtatgc aggagaaatc gttgagtatg gaacggttga ggaagtcttc tatgaccctc
    17161 gccatccata tacatggagt ctcttgtcta gcttgcctca gcttgctgat gataaagggg
    17221 atctttactc aatcccagga acacctccgt cactttatac tgacctgaaa ggggatgctt
    17281 ttgccttgcg ttctgactac gcaatgcaga ttgacttcga acaaaaagct cctcaattct
    17341 cagtatcaga gacacattgg gctaaaactt ggcttcttca tgaggatgct ccaaaagtag
    17401 aaaaaccagc tgtgattgca aatctccatg ataagattcg tgaaaaaatg ggatttgccc
    17461 atctggctga ctaggaggaa ggaaatgtct gaaaaattag tagaaatcaa agatttagaa
    17521 atttccttcg gtgaaggaag taagaagttt gtcgcggtta aaaatgctaa cttctttatc
    17581 aacaagggag aaactttctc gcttgtaggt gagtccggta gtgggaaaac aactattggt
    17641 cgtgctatca tcggtctaaa tgatacaagt aatggagata tcatttttga tggtcaaaag
    17701 attaatggta agaaatcgcg tgaacaagct gcggaattga ttcgtcgaat ccagatgatt
    17761 ttccaagacc ctgctgcaag tttgaatgaa cgtgcgactg ttgattatat tatttctgaa
    17821 ggtctttaca atcaccgttt atttaaggat gaagaagaac gtaaagagaa agttcaaaat
    17881 attatccgtg aagtaggtct tcttgctgag cacttgactc gttaccctca tgaattctca
    17941 ggcggtcaac gtcaacgtat cggtattgcc cgtgccttgg tcatgcaacc agactttgtt
    18001 attgcagatg agccaatttc agccttggac gtttctgtac gtgcccaagt cttgaacttg
    18061 ctcaaaaaat tccaaaaaga gctcggcctg acctatctct tcatcgccca tgacttgtcg
    18121 gttgttcgct ttatttcaga tcgtatcgca gttatttaca agggtgttat tgtagaggtt
    18181 gcagaaacag aagaattgtt taacaatcca attcacccat atactcaagc cttgctttca
    18241 gcggtaccaa tcccagatcc aatcttggaa cgtaagaagg tcttgaaggt ttacgaccca
    18301 agtcaacacg actatgagac tgataagcca tctatggtag aaatccgtcc aggtcactat
    18361 gtttgggcga accaagccga attggcacgt tatcaaaaag gactaaacta ataatggttt
    18421 tataatttcc atgtcaattt ttatgggaat tataaaactt ttttgttgga ctgatttgaa
    18481 aaactttgaa agcttcctga aaga
//
LOCUS       DAVBEM010000046        16132 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVBEM010000046 DAVBEM010000000
VERSION     DAVBEM010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16132
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.046"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            145..6831
                     /locus_tag="VQ548_001636"
     CDS             145..6831
                     /locus_tag="VQ548_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HET2654451.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTVEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQTSNQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDVDVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGFKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVARVRTLIGKEPKMPKTVGFVYSDGSREKLPVTWSQ
                     VDVSQAGVVTVKGTANGREVEAHVEVLAIAKELPTVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEDTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQIRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLRFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGKERIFT
                     AINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSEASQTN
                     KAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(7079..7935)
                     /locus_tag="VQ548_001637"
                     /pseudo
     CDS             complement(7079..7935)
                     /locus_tag="VQ548_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8146..8505)
                     /locus_tag="VQ548_001638"
     CDS             complement(8146..8505)
                     /locus_tag="VQ548_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HET2654452.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            8597..9553
                     /locus_tag="VQ548_001639"
                     /pseudo
     CDS             8597..9553
                     /locus_tag="VQ548_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            9537..10094
                     /locus_tag="VQ548_001640"
     CDS             9537..10094
                     /locus_tag="VQ548_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2654453.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            10087..10341
                     /locus_tag="VQ548_001641"
     CDS             10087..10341
                     /locus_tag="VQ548_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654454.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            10353..12407
                     /locus_tag="VQ548_001642"
     CDS             10353..12407
                     /locus_tag="VQ548_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HET2654455.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            12586..13446
                     /locus_tag="VQ548_001643"
     CDS             12586..13446
                     /locus_tag="VQ548_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HET2654456.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            13657..14367
                     /gene="ccdA2"
                     /locus_tag="VQ548_001644"
     CDS             13657..14367
                     /gene="ccdA2"
                     /locus_tag="VQ548_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET2654457.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            14387..14953
                     /locus_tag="VQ548_001645"
     CDS             14387..14953
                     /locus_tag="VQ548_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HET2654458.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            14964..16076
                     /gene="msrB"
                     /locus_tag="VQ548_001646"
     CDS             14964..16076
                     /gene="msrB"
                     /locus_tag="VQ548_001646"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET2654459.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
BASE COUNT         4901 a         3052 c         3564 g         4615 t
ORIGIN      
        1 catatctacg gcaaggcgac actgacgaag tttgaattgg attttcgcag agtgtaaatt
       61 gttgaaacta ggttgtcata ccatgtatac cacttgggct ttggtagtag ctaactgcac
      121 taaatataat ataaggaggg ttttatgggg aaaggccatt ggaatcggaa aagagtttat
      181 agcattcgta agtttgctgt gggagcttgc tcagtaatga ttgggacttg tgcagttcta
      241 ttaggaggaa atatagctgg agaatctgta gtttatgcgg atgaaacact tattactcat
      301 actgttgaga aacctaaaga ggaaaaaatg atagtagaag aaaaggctga taaagctttg
      361 gaaactaaaa atgtagttga aaggacagaa caaagtgaac ctagttcaac tgaggctatt
      421 gcatctgaga agaaagaaga tgaagccgta actccaaaag aggaaaaagt gtctgctaaa
      481 ccggaagaaa aagctccaag gatagaatca caaacttcaa atcaagaaaa accgctcaag
      541 gaagatgcta aagctgtaac aaatgaagaa gtgaatcaaa tgattgaaga caggaaagtg
      601 gattttaatc aaaattggta ttttaaactc aatgcaaatt ctaaggaagc cattaaacct
      661 gatgtagacg tatctacgtg gaaaaaatta gatttaccgt atgactggag tatctttaac
      721 gatttcgatc atgaatctcc tgcacaaaat gaaggtggac agctcaacgg tggggaagct
      781 tggtatcgca agactttcaa actagatgaa aaagacctca agaaaaatgt tcgccttact
      841 tttgatggcg tctacatgga ttctcaagtt tatgtcaatg gtcagttagt ggggcattat
      901 ccaaatggtt ataaccagtt ctcatatgat atcaccaaat accttcacaa agatggtcgt
      961 gagaatgtga ttgctgtcca tgcagtcaac aaacagccaa gtagccgttg gtattcagga
     1021 agtggtatct atcgtgatgt gactttacaa gtgacagata aggtgcatgt tgagaaaaat
     1081 gggacaacta ttttaacacc aaaacttgaa gaacaacaac atggcaaggt tgaaactcat
     1141 gtgaccagca aaatcgtcaa tacggacgac aaagaccatg aacttgtagc cgaatatcaa
     1201 atcgttgaac gaggtggtca tgctgtaaca ggcttagttc gtacagcgag tcgtacctta
     1261 aaagcacatg aatcaacaag cctagatgcg attttagaag ttgaaagacc aaaactctgg
     1321 accgttttaa atgacaaacc tgccttgtac gaattgatta cgcgtgttta ccgtgacggt
     1381 caattggttg atgctaagaa ggatttgttt ggttaccgtt actatcactg gactccaaat
     1441 gaaggtttct ctttgaatgg tgaacgtatt aaattccatg gagtatcctt gcaccacgac
     1501 catggggcgc ttggagcaga agaaaactat aaagcagaat atcgccgtct caaacaaatg
     1561 aaggagatgg gagttaactc catccgtaca acccacaacc ctgctagtga gcaaaccttg
     1621 caaatcgcag cagaactagg tttactcgtt caggaagagg cctttgatac ttggtatggt
     1681 ggcaagaaac cttatgacta tggacgtttc tttgaaaaag atgccactca cccagaagct
     1741 cgaaaaggtg aaaaatggtc tgattttgac ctacgtacca tggtcgaaag aggcaaaaac
     1801 aaccctgcta tcttcatgtg gtcaattggt aatgaaatag gtgaagctaa tggtgatgcc
     1861 cactctttag caactgttaa acgtttggtc aaggttatca aggatgttga taagactcgc
     1921 tatgttacca tgggagcaga taaattccgt ttcggtaatg gtagcggagg gcatgagaaa
     1981 attgctgatg aactcgatgc tgttggattt aactattctg aagataatta caaagccctt
     2041 agagctaagc atccaaaatg gttgatttac ggttcagaaa catcttcagc tacccgtaca
     2101 cgtggaagtt actatcgccc tgaacgtgaa ttgaaacata gcaatggacc tgagcgtaat
     2161 tatgaacagt ctgactatgg aaatgatcgt gtgggttggg ggaaaacagc aaccgcttca
     2221 tggacttttg accgtgacaa cgctggctat gctggacagt ttatctggac aggtacggac
     2281 tatattggtg aacctacacc atggcacaac caaaatcaaa ctcctgttaa gagctcttac
     2341 tttggtatcg tagatacagc cggcattcca aaacatgact tctatctcta ccaaagccaa
     2401 tgggtttctg ttaagaagaa accgatggta caccttcttc ctcactggaa ctgggaaaac
     2461 aaagaattag catccaaagt agctgactca gaaggtaaga ttccagttcg tgcttattcg
     2521 aatgcttcta gtgtagaatt attcttgaat ggaaaatctc ttggttttaa gactttcaat
     2581 aaaaaacaaa ccagcgatgg gcggacttac caagaaggtg caaatgctaa tgaactttat
     2641 cttgaatgga aagttgccta tcaaccgggt accttggaag caattgctcg tgatgaatct
     2701 ggcaaggaaa ttgctcgaga taagattacg actgctggta agccagcggc agttcgtctt
     2761 attaaggaag accatgcgat tgcagcagat ggaaaagact tgacttacat ctactatgaa
     2821 attgttgaca gccaggggaa tgtggttcca actgctaata atctggttcg cttccaattg
     2881 catggccaag gtcaactggt cggtgtagat aacggagaac aagccagccg tgaacgctat
     2941 aaggcgcaag cagatggttc ttggattcgt aaagcattta atggtaaagg tgttgccatt
     3001 gtcaaatcaa ctgaacaagc agggaaattc accctgactg cccactctga tctcttgaaa
     3061 tcgaaccaag tcactgtctt tactggtaaa aaagaaggac aagagaagac tgttttgggg
     3121 acagaagtag caagagttcg tacattaatt ggtaaagaac caaaaatgcc gaaaacagta
     3181 ggttttgtat acagcgatgg tagtcgtgaa aaacttccag taacttggtc tcaagtcgat
     3241 gttagtcaag caggagttgt gactgttaaa ggtacagcaa atggacgtga ggtagaggct
     3301 catgtcgagg ttctagcaat tgcgaaagaa ttaccaacag ttaaacgtat tgctccaaat
     3361 actgacttga attctgtaga caaatctgtt tcttatgttt tgactgatgg aagtgtacaa
     3421 gagtacgaag tagatagctg ggagattacg gaagtagata aagccaaact ttcagtagct
     3481 ggatcacgta ttcaaatgac tggtcagtta gctggagaaa ctattcatgc aacccttgtg
     3541 gtagaagaag gaaatgctgc agcacctgta gtgccaactg ttactgttgg aggtgaggca
     3601 gtaacaggtc ttactagtcg acaaccaatg caatatcgta ctctatctta tggtgcccaa
     3661 ctgccagaag tcacagcaag tgctgaaaat gctgatgtga cagttcttca agcaagcgca
     3721 gcaaacggca tgcgtgcgag catctttatt cagcctaaag atggtggtcc tcttcaaacc
     3781 tatgcaattc aattcctaga agaagcacca aaaattgctc acttgagttt gcaagtggaa
     3841 aaagctgaca gtctcaaaga agaccaaact gtcaaattgt cggttcgagc tcactatcaa
     3901 gatggaacgc aagctgtatt accagctgac aaagtaacct tctctacaag tggtgaaggg
     3961 gaagtcgcaa ttcgtaaagg aatgcttgag ttgcataagc caggagcagt cactctcaaa
     4021 gcggaatatg agggagctaa aggccaagtt gaactcacta tccaagccaa tactgagaag
     4081 aagattgcgc aatctatccg tcctgtaaat gtagtcacag atttgcatca aaaacctact
     4141 cttccaacaa cagtaacggt tgagtatgac aaaggtttcc ctaaagctca caaagtcact
     4201 tggcaagcta ttccgaaaga aaaactagac tcctatcaaa catttgaagt actaggtaaa
     4261 gttgaaggaa ttgaccttga agcgcgtgca aaagtctctg tagaaggtat cgtttcagtt
     4321 gaagaagtca gtgtgacaac tccaatcgca gaagcaccac aattaccaga aagcgttcgg
     4381 acatatgatt caaatggtca cgtttcatca gctaaggttg catgggatgc gattcgtata
     4441 gagcaatacg ctaaggaagg tgtctttaca gttaatggtc gcttagaaga tactcaatta
     4501 acaactaaac ttcatgttcg cgtatctgct caaactgagc aaggtgcaaa catttctgac
     4561 caatggaccg gttcagaatt gccacttgcc tttgcttcag attcaaatcc aagcgaccca
     4621 gtttcaaatg ttaatgacaa gctcatttcc tacaataacc aaccagccaa tcgttggaca
     4681 aactggaatc gtactaatcc agaagcttca gtcggtgttc tgtttggaga ttcaggtatc
     4741 ttgagcaaac gctccgttga taatctaagt gtcggattcc acgaagacca tggagttggt
     4801 gcaccgaagt cttatgtgat tgagtattat gttggtaaga ctgtcccaac agctcctaaa
     4861 aaccctagtt ttgttggtaa tgaggaccat gtctttaatg attctgccaa ctggaaacca
     4921 gttactaatc taaaagcccc tgctcaactc aaggctggag aaatgaacca ctttagcttt
     4981 gataaagttg aaacctatgc tgttcgtatt cgcatggtta aagcagataa caagcgtgga
     5041 acgtctatca cagaggtaca aatctttgcg aaacaagttg cggcagccaa acaaggacaa
     5101 ataagaatcc aagttgacgg caaagactta gcaaacttca accctgattt gacagactac
     5161 taccttgagt ctgtagatgg aaaagttccg gcagtcacag caagtgttag caacaatggt
     5221 ctcgctaccg tcgttccaag cgttcgtgaa ggtgagccag ttcgtgtcat cgcgaaagct
     5281 gaaaatggcg acatcttagg agaataccgt ctgcacttca ctaaggataa gaacttactt
     5341 tctcataaac cagttgctgc ggttaaacaa gctcgcttgc tacaagtagg tcaagcactt
     5401 gaattgccga ctaaggttcc agtttacttc acaggtaaag acggctacga aacaaaagac
     5461 ctgacagttg aatgggaaga agttccagca gaaaatctga caaaagcagg tcaatttacc
     5521 gttcgaggcc atgtccttgg tagtgatctt gttgctgagg tcactgtacg agtgacagac
     5581 aaactaggcg aagctctttc agataaccct aactatgatg aaaacagtaa ccaggccttt
     5641 gcttcagcaa ccaatgatat tgacaaaaac tctcatgacc gcgttgacta tctcaatgac
     5701 ggagatcatt cagaaaatcg tcgttggaca aactggtctc caacaccatc ttctaatcca
     5761 gaagtatcag cgggtgtgat cttccgtgaa aatggtaaga ttgtagaacg gactgttgcc
     5821 caagccaaac ttcgtttctt tgcagatagt ggtacggatg caccaactaa actcgtttta
     5881 gaacgctatg tcggtccaga gtttgaagtg ccaacctact attcaaacta ccaagcctac
     5941 gacgcagacc atccattcaa caatccagaa aattgggaag ctgtgcctta tcgtgcggat
     6001 aaagacatcg cagctggtga tgaaatcaac gtaacattta aagctgtcaa agccaaagct
     6061 atgagatggc gtatggagcg taaagctgac aagagcggtg ttgctatgat tgagatgacc
     6121 ttccttgcac cgagtgaatt gcctcaagaa agtacgcaat cgaagattct tgtagatgga
     6181 aaagaacttg ctgatttcgc tgaaaatcgt caagactatc aaattaccta taaaggtcaa
     6241 cggccaaaag tctcagttga agaaaacaat caagtagctt caactgtggt agatagtgga
     6301 gaagatagcc ttccagtact tgttcgcctc gtttcagaaa gtggaaaaca agtcaaggaa
     6361 taccgtatcc agttgactaa ggaaaaacca gtttctgctg tacaagaaga tcttccaaaa
     6421 ctcgaatttg ttgaaaaaga tttggcctac aagacagttg agaaaaaaga ttcaacactg
     6481 tatctaggtg aaactcgtgt agaacaagaa ggaaaaactg gtaaagaacg tatctttaca
     6541 gcgattaatc ctgatggaag taaggaagaa aaactccgtg aagtggtaga agctccgaca
     6601 gaccgcatag tcttggttgg aaccaaacca gtagctcaag aagctaaaaa accacaagtg
     6661 tcagaaaaag cagatacaaa accaattgat tcaagtgaag ctagtcaaac taataaagcc
     6721 cagttaccaa atacaggtag tgcggcaagc caagcagcag tagcagcagg tttagctctt
     6781 ctaggtttga gtgcaggatt agtagttact aaaggtaaaa aagaagacta gaaattttga
     6841 taccttcttt atcattaaag accaaagaaa aactcttgtc ctaaatagaa gataaagagt
     6901 ctggaacaaa atagttctca accacaaaaa agctagatat ttccaattgc ggaactctag
     6961 ctttttaatt ttgagtcgtt ctcttattgt atagtagatt gaaactagaa tagtacactt
     7021 ctacttctaa aacattgtta gaaatcaatt tgactgtcct tatcgatttg tcctgttctt
     7081 atttcatttc actatgtttt aggaggttat tggccataag taccaatccc atgtcaattc
     7141 tcacttgacg cttccctctc agattacatc tcttgtaacc caaacaagcc tttatctgcc
     7201 caaagacagg ttccacatca atcttgcgtt gagcgaaaat ctgtctacct tggggagata
     7261 aaagcgcctg acattcttta gctttcaagt tttgatagcg ttcgttcata tacagtccct
     7321 tttgagggac tgattcaggt tcatcagcgt agtaaacctt gatttcctgt tgaaagtctg
     7381 tctgtgtttt ctggtacttg atatggtgaa aacgatagca ccagccatca ggatgtgtgt
     7441 agctatcctc cttgtcatta tagtgccaat tcgctaagtt tttagctgac tgtttatacc
     7501 ctctcttttg ttccttatca aacatggcat atttaatcag aaggggagtg atttcttctt
     7561 gaaaatagac ctgtatctgt tcttgaagtt tggcggagaa tttctctgtc gttttcttcc
     7621 acacaaaact atacttgttg gcattggctt caatcttagt tccgtcaata aacaaacaat
     7681 ctaaggtcac taactcttcc atttttcaat ttttcgacca gagaaaatcc cttgtgaata
     7741 ggcaaataga agagtagata caagcatttt agggtgataa gacgggcgat caaaggcatg
     7801 atagaaggcg tggaagtgac aatcctccaa ggtattcacc actttttcaa tagtaaaaac
     7861 gagatgatct tgtggcaaga aggaactgat ttctagtggt aaagttgttt gatttgtgtt
     7921 atagtgaata tgcatgggat agcctttcta aatggtttat taagcaattc tattttacca
     7981 agactatcgc aaccatgcaa aaaagcaacg gcaaatccgt tgcctttttt ggagataaga
     8041 gactattgtc ccagactctt ttctttgtat aaaattgtat agtgttattg tctatactat
     8101 tttgtagaga aagcaaaaat ccctagaaaa tgcttaggga ttcgactatt tcattaagaa
     8161 caattcaaca atcatttcta tatacatgat aagggttaat aagaatcctg cacgccagaa
     8221 gaatttgata aatttaggat agtaaaagct gcgttttttc aaaaggaaga aaaagacgag
     8281 aataatggct aggatcgaga gggctagccc cagtctaggg aggaaattat gggtaaaggt
     8341 tttagctgta atcaagtaat actcaaatac caagactgga aaagccaaat ccgcaaagtt
     8401 tcgtcctagt ttttttaatc taaaaagttt ggttaggata atgcagacga ctaaggtcag
     8461 tatcaataat aaaatagatg ctaatttcat taaaatcata cccatattgt atcataaaaa
     8521 aaggctaatg gaaacgagaa acagaggaat ttataggaaa gtcaggcttt tgagattgtg
     8581 ggtgattttt gttataatga aagttataaa atcttataat accttgaatg attattatcg
     8641 aaaactcttt ggagaaaaga cttttaaagt ccctattgat gcgggatttg actgtcccaa
     8701 tcgtgatgga actgtggctc atggaggctg tactttttgt acggtttccg gttctggaga
     8761 tgccattgtg gcaccagatg cgcctatccg tgagcaattt tataaggaaa ttgactttat
     8821 tcatcgtaag tggccagatg ttcagaagta tctggtttat tttcaaaatt ttaccaacac
     8881 ccatgaaaag gtggaagtta ttcgagagcg ttatgaacag gctatcaatg agccaggtgt
     8941 ggtaggaatc aatattggaa cgcgcccaga ctgtttacca gacgaaacca tcgaatattt
     9001 ggctgagtta tcggagtgca tgcatgtgac ggttgaattg ggcttgcaaa ctacttatga
     9061 agcaacctct gacctgatta accgtgcgca ttcttatgaa ttgtaggtgg aaacggtcaa
     9121 gcgtttgaga aagtatccaa aaattgagat tgtttcccat ttgatcaatg gtttgcctgg
     9181 tgaaacccat gagatgatgg ttgaaaatgt ccgccgttgt gtcacggata acgatattca
     9241 agggattaaa ctgcatttgc tccatcttat gacaaatact cgtatgcaac gagattacca
     9301 tgaggggcgt ttacaattga tgagtcagga cgaatatgtc agggtcatct gtgaccaact
     9361 ggaaattatt cccaaacata tcgtcatcca tcgaattaca ggagatgcgc ctagggatat
     9421 gctgcttggg cctatgtgga gcctcaataa atgggaagct ctcaacagca ttgagatgga
     9481 gatgcgacgt cgtggaagtg ttcaaggatg caaggctgta aaacaggagt ttgaaaatga
     9541 aaagaccact tgagatggca catgattttt tggctgaggt cgtgacaaaa gaggatgtcg
     9601 tagtggatgc gactatggga aatggtcatg acacgctttt tttagccaag ctagccaagc
     9661 aagtctatgc ctttgatatt cagaagcaag ccttggaaaa gacccaagag cgtttgcatc
     9721 aggctgactt gacaaatgcc cagttaatct tgcaaggcca tgagacactg gaccagtttg
     9781 tgataaaagc taaggcaggg atttttaatc tgggctattt gccgtcagct gataagtctg
     9841 tcatcacccg accgcagaca acgattgagg cattagaaaa gctatgtggc ttacttgtca
     9901 aaggtggacg aattgctatt atgatttact atggtcatga aggaggcgat ctcgagagag
     9961 atgctgtctt ggattttgtg atccagttga accaacaaga gtacacagct gccatttacc
    10021 gaactttaaa ccaagtcaac aacccgccgt ttttagtgat gattgaaaaa ttagagagat
    10081 acagacatgg ataaacaata cctacacgaa aagctggatg ccatgcgcca gaattttgtt
    10141 gaatcaaccc accacgaacg atcggtgggc gtgctagacc aagcgcatat gagcaaaaaa
    10201 atgcttaaaa tcaagaaaaa attagttgct cttgaaatgg aacggtgcca gagaaaaatt
    10261 gagcacaaag actgttccaa gattgaccaa aaaatcaaag agcagaagga gatatttgaa
    10321 tcctgttgta aaaaagatta aggaggacgt gcgtggaatt actgatttac ctcatcctat
    10381 ttttactggt tttgattgtc tcaagtacaa ccaataagct cctgcccttt ttgcctctcc
    10441 ctttggtgca gattcttttg ggaattgtga ttggtctctt tttacccaat actgactttc
    10501 accttaatac ggagttgttt ttggcactgg ttatcggacc cttgcttttc cgagaggctg
    10561 aagaagcaga tgttacggct attttaaaac actggcgaat cattgtttat ctcatatttc
    10621 cagtgatttt tatctcgacc ttgagtttgg gtggcttggc ccatcttctt tggttcagcc
    10681 ttcccttggc agcttgcttg gctgttgggg cagcccttgg tcctacggac ttggtggcct
    10741 ttgcctctct ttcggagcgt tttagctttc ctaagcgcgt gtccaatatt cttaagggcg
    10801 aaggactctt gaatgatgct tctggtttgg tggcttttca ggtagctttg acagcttgga
    10861 caactggagc tttttctctg gggcaagcta gcagttcgct catcttttca atcctaggcg
    10921 gttttttaat tggattttta acggccatga ccaaccgctt cctccatacc ttcttgctaa
    10981 gtgtgcgcgc aacggatatt gccagtgaac ttttattaga attgagtttg cctctagtga
    11041 ccttctttct ggcagaagaa gttcatgttt caggtattat tgccgtcgta gttgctggaa
    11101 ttttaaaggc aagtcgcttc aagaaaatca cgctcctcga agcccaagtg gatacggtga
    11161 ccgagacggt ctggcataca gtgaccttta tgctcaacgg ttctgtcttt gtgattttag
    11221 ggatggagtt ggaaatgata gcagaaccta tcttgaccaa tccaatctat aatcctctac
    11281 ttttattgct atctctcatc gcccttacct ttgtcctctt tgtcattcgt tttattatga
    11341 tctatggcta ttatgcctat agaacccgac gcctcaagaa aaagctaaat aagtatatga
    11401 aggacatgtt tctcttgacc ttttcaggtg ttaagggaac ggtgtcgatt gctacgattc
    11461 tcttgatacc aagtaatcta gaacaggagt atcctctttt gcttttcctt gttgcaggtg
    11521 tgacgcttgt cagcttttta acaggtctct tggtcttgcc tcatctttct gatgaagagg
    11581 aagaaagcaa ggattatctc atgcatatcg ccattttgaa tgaagtaacg ctagagttgg
    11641 aaaaagagtt ggaagacacc agaaataaac ttcccctcta tgcggctatt gacaattatc
    11701 atggacgtat tgaaaatctc attttaagcc aagaaaacca ggatgatcaa gaagattggg
    11761 ctgctttgaa actcttgatt cttagtattg aaagtgatgg tttggaacag gcctatgaag
    11821 aggggaacat tagcaatcgt gcttaccgag tttaccaacg ttatctgaaa aatatagaac
    11881 aaggaatcaa tcgtaaactt gcctcaagac tgacctatta ttttcttgtt tccttgagga
    11941 ttttacgttt tctccttcat gaagttttta ctcttggaaa gaccttccgt agctggaagg
    12001 acaaggagca aagccgtctc cgtgctcttg attatgacca aattgcagag ctctatcttg
    12061 ccaatacaga gatgattatt gaaagtttgg aaaacctgaa gggagtctac agacgctctt
    12121 tgattagttt tatgcaggag tctcgtcttc gagaaacagc tattatcagc agtggtgcct
    12181 ttgtcgaacg ggttatcaat cgtgtcaaac ccaacaatat cgatgaaatg ctgagaggct
    12241 attatctgga gcgcaagttg attttcgaat acgaagaaaa acgattgatt acgactaagt
    12301 atgccaagaa attacgacaa aatgtaaata acttagagaa ctattccttg aaggaagctg
    12361 ccaataccct gccgtatgat atggtggaat tggtaagaag aaattagtta atactcttcg
    12421 aaaatctctt caaaccacgt cagcgtcgcc ttggattata tatgtgactg acttcgtcag
    12481 tttcatctac aacctcaaag cagggctttg agcaacctgc ggctagcttc ctagtttgct
    12541 ctttgatttt cattgagtat aagattataa atgaaggagt atgacatgaa aaagtggtgg
    12601 aaagagctga tagacaagcc tttattaaaa gcttttttgc attattatca agcatcagat
    12661 agtgagttga ccagtgtcgc agtagcctac tattggttga tttcgatttt ccccctgctt
    12721 ttggtggtgg tcaatatcct cccctatttt cagattcctg tgggagaatt tctgtgcttt
    12781 atgaaagacg ttctgccccc aagcctctat gaaggtgtgg aaaaaatagc cagagaagtt
    12841 ttgacgcaac cttcaacagg tttattgagt ttttctgttt tatcggcgtt atggagtttt
    12901 tcaaaatcta tgaatttctt gcaaaaagct tttaacaagg cttatggcgt cgaaaagagt
    12961 cgtggactta tttcccatca gatgctaagt ctcctagtca gttttggctt gcagctcctc
    13021 tttgcgtttg ccttgttttt gatcttattt ggtcagatga ttttggcttt acttgctcat
    13081 tattggacaa aagatggcat tatctatcag gctttacaag ggttggcagg tcctctgatt
    13141 tacgccctcc tctttgctat cttggtcatg ctttattatt ttcttcccaa tctatctaac
    13201 aggaaaatta gctataccct accaggcagt gcctttgttc tcttagtgat tttaggttta
    13261 ctaactctgt tctctagtta tctcaattac tatgtccatc atttggtgga tgtccgaatt
    13321 ttaggttccg ttcttcttgt tgttatgatg ttttggttta tcttgattgc taaaattgtt
    13381 atcctaggcg cggttatcaa tgccagtatg cagagtttga aagatccggt ctttaaaaaa
    13441 gactaactat ttatccatta caaaagcgca tagtatcaaa actttataga accttgatac
    13501 tatgcgcttt tgtgctttga cagttttttg tatagttttt gtccaagatt tctaaatcat
    13561 ctgattaaat tcctattttc ccctatcatt gtccctgttt tttcgaaaat ggaaggagta
    13621 taataaatct atcaataaaa tgataggagg aactttatgg gtcatatttt cttttttcta
    13681 agtgtctttt tggcagggat tctatccttc ttttctcctt gtatcttacc tttgttaccg
    13741 gtctatacag gagtgttact agatgataag gatggtgctc aggcttctag cggcaaattt
    13801 tcaatctcag ttactagttt attacgaact ctggccttta tagcaggaat ttcctttata
    13861 tttattttgt tgggctatgg agctggtttt ttaggcgatt tgctttatgc ttcttggttc
    13921 caatatctta ctggggcaat tattatcctt cttggtttgc accaaatgga gattctacac
    13981 tttaaggggc tttataagga aaagaggcta caactgcaag gacaggggca aaatggtaag
    14041 ggctatagtc aggcattttt attgggcttg acctttagtt ttgcttggac gccttgcgtg
    14101 gggccggttc tggggtctgt tttggccttg gcggcttcag gtggttcagg agcttggcag
    14161 ggagctggtc tcatgttggt gtatacgctg ggcttggcgc taccattctt gcttctagct
    14221 ctgacctcta gttatgtttt gaaacatttc cgaaaacttc atccctatct cggaatcctc
    14281 aaaaaagtgg gtggttttct cattattgtg atgggactct tggttctgtt tggaaatgct
    14341 tcaattttaa gtcaattatt tgaataaaat ggaaaggaat atcaatatga aaaaatggca
    14401 aacatgtgtt cttggagcag gttcgctcct ttgtttgacg gcttgttcag gcaagtccgt
    14461 gactagtgaa caccaaacga aagatgaaat gaagacggag cagacagcta gtaaaacaag
    14521 cgcagctaaa gggaaagagg tggctgattt tgaattgatg ggagtagatg gcaagaccta
    14581 ccgtttatct gattacaagg gcaagaaagt ctatctcaaa ttctgggctt cttggtgttc
    14641 catctgtctg gctagtcttc cagatacgga tgagattgct aaagaagctg gtgatgacta
    14701 tgtggtcttg acagtagtgt caccaggaca taagggagag caatctgaag cggactttaa
    14761 gaattggtat aagggattgg attataaaaa tctcccagtc ctagttgacc catcaggcaa
    14821 acttttggaa acttatggtg tccgttctta cccaacccaa gcctttatag acaaagaagg
    14881 caagctggtc aaaacacatc caggattcat ggaaaaagat gcaattttgc aaactttgaa
    14941 ggaattagcc taggaggtgt cttatgaatg ataagttaaa aatcttcttg ttgctaggag
    15001 tattttttct agccataacc ggtttctatg ttctattgat acgaaatgca gggcagacag
    15061 atgcctcgca aattgaaaag gcggcagtta gccaaggagg aaaagcagtg aaaaaaacag
    15121 aaattagtaa agacgcagac ttgcacgaaa tttatctagc tggaggttgt ttctggggag
    15181 tggaggaata tttctcacgc gttcccgggg tgacggatgc cgtttcaggc tatgcaaatg
    15241 gtagaggaga aacaaccaag tacgaattga ttaaccaaac aggtcatgca gaaaccgtcc
    15301 atgtcaccta tgatgccaag caaatttctc tcaaggaaat cctgcttcac tatttccgca
    15361 ttatcaatcc aaccagcaaa aataaacaag gaaatgatgt ggggacccag taccgtactg
    15421 gtgtttatta cacagatgac aaggatttgg aagtgattaa ccaagtcttt gatgaggtgg
    15481 ctaagaaata cgatcaacct ctagcagttg aaaaggaaaa cttgaagaat tttgtggtgg
    15541 ctgaggatta ccatcaagac tatctcaaga aaaatccaaa tggctactgc catatcaatg
    15601 ttaatcaggc ggcctatcct gtcattgatg ccagcaaata tccaaaacca agtgatgagg
    15661 aattgaaaaa gaccctgtca cctgaggagt atgcagttac ccaggaaaat caaacagaac
    15721 gagctttctc aaaccgttac tgggataaat ttgaatccgg tatctatgtg gatatagcaa
    15781 ctggggaacc tctcttttca tcaaaagaca aatttgagtc tggttgtggc tggcctagtt
    15841 ttacccaacc catcagtcca gatgttgtca cctacaagga agataagtcc tacaatatga
    15901 cgcgtatgga agtgcggagc cgagtaggag attctcacct tgggcatgtc tttacggatg
    15961 gtccacagga caagggcggc ttacgttact gtatcaatag cctctctatc cgctttattc
    16021 ccaaagacca aatggaagaa aaaggctacg cttatttact agattatgtt gattaatact
    16081 cttcgaaaat ctcttcaaac cacgtcagcg tcgccttacc gtatgtaggg tt
//
LOCUS       DAVBEM010000047        15156 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVBEM010000047 DAVBEM010000000
VERSION     DAVBEM010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15156
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.047"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            369..2087
                     /locus_tag="VQ548_001647"
     CDS             369..2087
                     /locus_tag="VQ548_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HET2654460.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            2198..2545
                     /locus_tag="VQ548_001648"
     CDS             2198..2545
                     /locus_tag="VQ548_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET2654461.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(2823..3659)
                     /locus_tag="VQ548_001649"
     CDS             complement(2823..3659)
                     /locus_tag="VQ548_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2654462.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(3672..4301)
                     /locus_tag="VQ548_001650"
     CDS             complement(3672..4301)
                     /locus_tag="VQ548_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2654463.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLDNLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(4311..4952)
                     /locus_tag="VQ548_001651"
     CDS             complement(4311..4952)
                     /locus_tag="VQ548_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2654464.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(5098..6327)
                     /locus_tag="VQ548_001652"
     CDS             complement(5098..6327)
                     /locus_tag="VQ548_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HET2654465.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEESENLLT
                     KWMIARSYQEMDDLDTAYEHYQELIGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(6317..7483)
                     /locus_tag="VQ548_001653"
     CDS             complement(6317..7483)
                     /locus_tag="VQ548_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET2654466.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            7627..8640
                     /locus_tag="VQ548_001654"
     CDS             7627..8640
                     /locus_tag="VQ548_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HET2654467.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(8685..9104)
                     /locus_tag="VQ548_001655"
     CDS             complement(8685..9104)
                     /locus_tag="VQ548_001655"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HET2654468.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDQVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(9115..10521)
                     /gene="atpD"
                     /locus_tag="VQ548_001656"
     CDS             complement(9115..10521)
                     /gene="atpD"
                     /locus_tag="VQ548_001656"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HET2654469.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(10607..11485)
                     /locus_tag="VQ548_001657"
     CDS             complement(10607..11485)
                     /locus_tag="VQ548_001657"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HET2654470.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(11501..13006)
                     /locus_tag="VQ548_001658"
     CDS             complement(11501..13006)
                     /locus_tag="VQ548_001658"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HET2654471.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALIHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(13021..13557)
                     /locus_tag="VQ548_001659"
     CDS             complement(13021..13557)
                     /locus_tag="VQ548_001659"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HET2654472.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(13557..14051)
                     /gene="atpF"
                     /locus_tag="VQ548_001660"
     CDS             complement(13557..14051)
                     /gene="atpF"
                     /locus_tag="VQ548_001660"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HET2654473.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(14065..14781)
                     /gene="atpB"
                     /locus_tag="VQ548_001661"
     CDS             complement(14065..14781)
                     /gene="atpB"
                     /locus_tag="VQ548_001661"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HET2654474.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(14816..15016)
                     /locus_tag="VQ548_001662"
     CDS             complement(14816..15016)
                     /locus_tag="VQ548_001662"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HET2654475.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
BASE COUNT         4661 a         3348 c         2745 g         4402 t
ORIGIN      
        1 ttgttcacgt ctttcttttc ccacgtgaag agagttctga cgccaacacc aaaaaacttt
       61 ggccgcctcg acatgtctgt gccctccttt gatggaatct aatgctcctt gtttaaaatc
      121 agtattatat gccatagctt tattagacca tgcttatttt aaactaagca actatatcaa
      181 tgttttgtta tgagaagact tacttttttt actgaaattg aatttttcct agcctcaaca
      241 tcatataacc ccaaaattca atctgacctg gtttgaagag atgttcgaag cagataaggt
      301 tttactaaaa ctaaaaaaaa tgatataatc aaactgatta aatgttttaa aaataaagga
      361 gaatttgaat gtcttaccaa gaaaattacc agaaatgggt tgattttgtg gagcttcctg
      421 actaccttcg tcaagatttg gaaaatatgg acgaaaaaac taaggaagat gccttctata
      481 caaatcttga atttggtact gcaggtatgc gtggcttggt tggtgctggt acaaaccgta
      541 tcaacatcta cgttgttcgc caagctactg aaggattggc tcgtttgatt gagtcaaaag
      601 gtggaaacga gaaagaacgc ggtgtagcaa ttgcctacga tagccgtcac ttctcacctg
      661 agtttgcctt tgaatctgcg gcagttcttg ctaaacacgg catcaaatct tacgtatttg
      721 aaagccttcg tccgactcca gaactatcat ttgcagttcg tcatctcaac tgtttcgcag
      781 gtatcatggt cacagccagc cacaaccctg ctccatttaa cggttacaag gtttacggtg
      841 aagacggtgg acaaatgcct ccacacgatg cggacgcttt gactacttat atccgtgcaa
      901 tcgaaaaccc atttgcagtt gaagttgctg atgtggaaac tgaaaaagct tctggcttga
      961 ttgaagttat cggcgaagct gttgacgtag aataccttaa agaggttaag gacgtaaaca
     1021 tcaacccagc cttgattgaa gaatttggta aagacatgaa gattgtctac acaccacttc
     1081 atggtactgg tgaaatgttg gctcgtcgtg ctcttgccca agcaggattt gactctgttc
     1141 aagttgttga agcgcaagca actgctgacc cagacttctc aactgtaaca tctccaaacc
     1201 cagaaagcca agcagccttt gcccttgctg aagaacttgg tcgtcaagtt ggtgcagatg
     1261 ttcttgtcgc aactgaccca gacgctgacc gtgttggtgt tgaagttctt caaaaagatg
     1321 gtagctacct caacctttca ggtaaccaaa tcggtgctat catggctaaa tacatcttgg
     1381 aagctcacaa aaacgctgga actcttcctg aaaatgccgc tctctgcaaa tctatcgttt
     1441 caactgactt ggtaacgaag attgctgaaa gctacggcgc aactatgttc aacgtcttga
     1501 caggtttcaa atttatcgct gaaaaaatcc aagaattcga agaaaaacac aaccacactt
     1561 acatgatggg atttgaagaa agcttcggtt acttgattaa accatttgta cgtgataaag
     1621 atgccatcca agccgttctt gtcgttgctg aacttgctgc ctactaccgt tctcgtggtt
     1681 tgacacttgc tgacggtatc gaagaaatct ataaagaata tggctactac gcagaaaaaa
     1741 caatctctgt tactctttca ggtgtcgatg gtgctgaaca aatcaaagcg attatggcta
     1801 aattccgcaa caatgctcca aaagaatgga acgcaacagc tatcactgtc gtagaagact
     1861 tcaaggcaca aactgctact gttgctgacg gtactgttac aaacttgaca actcctccaa
     1921 gtgatgtgtt gaaatacaca cttgctgacg gttcatggat tgccgttcgc ccttcaggta
     1981 cagaaccaaa aatcaagttc tacattgcag ttgtaggaga aaccaacgaa gaatcacaag
     2041 ctaagattgc taacatcgaa gcagaaatca atgcatttgt aaaataaaga cctataaaag
     2101 atgagaccaa ccaacctcat cttttttcgt atcaaatcta agcaatttta gaaactttat
     2161 ggcatactag acttatcaat gaaagcgagg taatctcatg gaacaatttt tagataacat
     2221 caaagacctt gaagtcacta cagttgtgcg tgcgcaagaa gctcttgata aaaaagaaac
     2281 tgcaaccttc tttatcggtc gcaaaacttg cccttactgc cgtaaatttg caggtacatt
     2341 gtcaggtgtc gtagctgaaa ccaaagctca catttacttc atcaatagtg aagaaccaag
     2401 ccaactcaat gatttgcaag cattccgctc acgctatgga atcccaactg taccaggttt
     2461 tgttcatatt acagatggac aaatcaacgt ccgttgcgac tcttcaatgt cagcacaaga
     2521 aatcaaagat ttcgcaggat tgtaaaaaat cagctaacaa gtcttaaaat cacaaaaacg
     2581 cataatgtaa ggtgcaaaaa ccttgatatt atgcgtttta ttgttcctaa aacagttaca
     2641 tcagcatttc attacagaac attttaattt tggaagtcaa atcaattttt aacaatgttt
     2701 tagaaatcac agtgggctat tccatattaa attatccaga ttcaatcgct attatcgttt
     2761 tcctagatta caaaaaaact gcgttttgct aatcaaaacg tagtctcagc cactatttta
     2821 tcttactgtc cttcttttac ttctttggtt gctacatctt ctccaaacca tttttggctg
     2881 atttcttgga acttgccgtc cttgtaaaga ctagaaaaag cttcatttat cttcttaacc
     2941 aaggttgtat cttccttacg ggctccaacc gcaaaagctt ctgtttctag tccaactgta
     3001 aagacattat aatcgtttaa aacaccttct gcttctaaat aatagtttgc atagacacgg
     3061 tcaatcaata gaccatcaat tcgatcgttt ttcaaatcaa tcaaggcttc attaaaggtt
     3121 tggtattgat tcgcttcctt attagcgaca atattcttca aaatttctgg atttgcttca
     3181 aagtccgcat aaccagatga accagcttga gctcctaatg tctttccagt catatccttt
     3241 gcagtcgtga taccagatga tttcttcgta accaatacct gctcattctt catatatgag
     3301 ttactgaaag ccaccttttc acggcgttcg tctgtagcgg aatagccatt ccaaatcaga
     3361 tcaatcgttc cttttgtcaa ttcagcttct ttcaaatccc aatcaatcgg ttgccaattt
     3421 accgtgattc cgtatttttc aaaaacagct gtagctaaat caatatcaaa tcctgcataa
     3481 gaaccatctt tctgagcaaa tcccattgga acaaaagtac tatcaaatcc aatagtaata
     3541 gacttgttag actggtactt tgaccaatta tctccactag tttcgctaga atttttccca
     3601 caagctacta agaacaaagc agtcatcaga ctgactaata caagcatcca ttttttcatc
     3661 catttttcct cctatttagg ttctactttc aataatacat ctgcgatatt ttcagcaaac
     3721 tgcaaatcat gggtaaccac aatctgggtc atcccaagtt ccctattttg caagattagc
     3781 ttctccactt ccaaacgtaa ttctggatcc agggcagaag ttggttcatc gtagccaatg
     3841 atttctgggt caatcatcat agcacgcgcc aaagccaccc gctgcttttg cccaccagat
     3901 agtgagaaag gataggcctc tgcgtgtcct cctagtccta actgttccaa gagtccactc
     3961 gccttcttct cagcctcttc ctgcttcatt cccatggtct tcacaggcga taaggtcaaa
     4021 ttgtccagaa ctgataaatg agggaacagt tgaaaatctt ggaatacaaa tcccagtaga
     4081 ttgcgcttct gcaattcatc cagctctaaa ggttgtccat tataaaagat ttgccctgaa
     4141 tcaatggttt caagacctgc aagcatacgt aaaagagttg tcttacctcc accagaaggt
     4201 ccaacgatag ccaggatttg cttttcagga atacttagac tgaaattaga caggatttgt
     4261 ttgtctccaa agactttatt gatatttcgt aattctaaca tggcagcctc ctatctataa
     4321 taactatact tcttctcaac ttttttggaa ataattgtca caatcccaat caaaatcaaa
     4381 taaatggctc ctgccaagaa cataggaact agactagcat cgcggttagc agctgttcga
     4441 ctagccaaga taaggtctga aattccgaga gcatagacca aagaagtatc cttgaccaaa
     4501 ctcataactt cattaaagac actaggaaga acgatcttgg tcacttgggg caagataata
     4561 tagcgcactc tgtcaaaagg gctaaacttc aagaccttgg cggcctcata ctgtcctctt
     4621 ggaatagtgt caattccccc acggaaaatt tctgcaaagt aagctgcata gttgagaaca
     4681 aaggcaataa tagctgcagg aaggcggtct aaacgaatcc caatacttgg gagcacataa
     4741 tagataaaaa tcagttgcaa gagtaagggg gttcctcgca taacccagat gtaaatgtta
     4801 atcagataat ggaggggctt ccaatggact tgcaaggcaa aggcaatcaa aacgcccaag
     4861 ggaatcgaaa atagcaagac cagtgcaaag acctgtacag tcgtgctcgc accattcagt
     4921 aaactcggta atatctcaaa taaataagac atactgcacc tcctaaaagt aattgttcct
     4981 attatagcat gaataaacaa gattaccaag tatttttgta aaaagattct accatataca
     5041 aataaaaacc gtagctatca aaagagataa actacagttc tatatgttta aacattctta
     5101 caatctctca aacagttctt gcatttgcac atcatctgga accagtttta agtaagtgtg
     5161 agcatggact tttgcttctt caaaatgtcc caattcacgc aagagataga tatagtgttc
     5221 cagaaattct ggattgtcct tcaaatctcc tatcaactct tgataatgct cataagcagt
     5281 atccaaatcg tccatttctt gataagaacg agcaatcatc cacttggtca aaagattttc
     5341 tgactcctca ctctgcaagt ctagaatatc ctcataacgc tcctgctcca gataaatagt
     5401 ggctaaacga agcaagattt cttctgtatc ctcagcgtct tcttttgcag taaggagata
     5461 attttctgca ccactagcat catgcaattc ataagaaaat tgtgaagcag ctagcaagag
     5521 gcgagtttca aagggatttt tctctaatcc ttgcttagcg atacgcaggg cttcttgaac
     5581 ttgatgttcc ttatgtaaag cctgactgta cccatactca tagccttcaa agtcaggaga
     5641 aatggtatca agctgcttaa agtagagggt ggctttttga tattcttctt gatcaaaata
     5701 aagactggcc aactcaaaag ctgttaagtc atcgtattct aactccaggg ctttttctaa
     5761 aaactcagta gccgtttcaa atttccctaa ctgagcatag gcaaagccaa ttcgttgata
     5821 ggtggaaatg cccgtttgct cataaatcga gcgattatct aactgggcat aggcttgaat
     5881 agccgcttgg taattttcca actcactatc caactctgcc aaacccaata tcaagagaga
     5941 atcctctgag taggtcaagg cctccaataa tttctcacgt gccacatctg tcaaaccttc
     6001 cagctggtaa aggtctgcct tcagagccaa agacgagaca taccagtcac tgtcagcttg
     6061 gatttcctca agataggtaa aggcttcttc tatttgacca tcctcgctag caattgcagc
     6121 tagattaaga tgaacctctg gaaaatcctc tacaattttc aggtaaattt ccttggcctg
     6181 aggatagaaa ccaatccctt caagataagt tgccaactca tacagaagat cacttgaatc
     6241 attttctaaa gctttggcga aataatgctc agccttagtt aaatcttgct cctccaaagc
     6301 ctgtaacatc tgttgactat tgttcactct tgacttcctc accctctaat tcatatagac
     6361 cactgactac cttataccat tcgaaaatgg ctgaaatgac aaccttagca gaggcataaa
     6421 ccggaatacc aagtaaaact ccccagatac caaacataga tcctgaagtt aacaaaacaa
     6481 agagaacatt aatagggtgg atgtttaatt gacttcccaa aatcaatgga gagacaaaac
     6541 ggccttcaat agtttgttct acgataaaga caatcactac tttcaaaagc atgactggac
     6601 cagcaatcaa acccaatact agagcaggaa gcatggctag aaagctacca agataaggga
     6661 ccagatttaa aataccagca gtaaccccca gcgtaaccgc atagcgtaga ccaataatct
     6721 tgaagaagat gataaacatt actgctacaa taatagccac tgtcacttgc cctcgaacat
     6781 agttggacaa ctgttgattc acatctgata aaacttgtcc aacaggttcc ttcaattttc
     6841 ttggaatgaa ttgggtcaaa tagttacgca agcctttccc atcacgcaag agataaaaga
     6901 gcatgaaagg aacgataatc aaggcaacaa tcacttgaga agctccgcta ataaaggcac
     6961 tcacccagtt gactgcctga gatgaaacct tacttgccaa aactgtagcc tggctagaaa
     7021 aattggtcaa aacttgctct aattgaggtc tgaaatcatc tggcaggtgc tgggctacca
     7081 atccattaac aatcctatct atatcttcta agtaaacagg aacgtttctt gcaaaggtca
     7141 aaacctgacg ttgcagattt ggaatggcga ctgccaagcc ccaaatgata aagagagcga
     7201 tgataacaaa gacaatagtg atagctataa cacgattaac cttatgcttc tccatccaat
     7261 caacaatagg attcaacaaa taatataaca aaccagacaa aatgactggc aacatcacaa
     7321 ctgctaaaaa gtctaaaaca ggtgaaaata gaaaactaat cttacttaaa ataaaaagat
     7381 tcagtcccaa taataaggtt actaaaaata ccgtaattgc cttgttatct aaaaaccact
     7441 tgaaaaacca agataggcta aaatgtttct ctttttgctc cataaatact tcctttctat
     7501 tgttctctca ttataccatt tttgaaacaa aataactctt ttttaaagtg cttacatcta
     7561 attggatatc tttaatttac ttgtttttgt gatataatag tcttatcttt acacagaggt
     7621 atagtaatga aagaaactgt ttattttgga acttatacac gtcgtacttc tcaagggatt
     7681 tacaaggcag actttgatac agaaactggt cagctttcaa atctagaact ttttgcagct
     7741 gagccaagtc caacctacct tgcctttgac cagcaccaac atttatacac tgttggtagc
     7801 caagacgata aggggggaat tgcagcctat caaactgacg ggactgtgtt aaatcatgtt
     7861 gttgaagaag gagctcccca ctgttatgtt gctgtcgatg aaaagcgtga tttggtttac
     7921 gcagccaact atcacaaggg acaagtcctt gtttataaac gccaggaaga tggtagtctt
     7981 ctacttagtg atatggatca acacagtggc caaggtccac atgaaaatca agcttccccc
     8041 catgttcact atacagattt aacacctgac cactatctag tgacctgcga cttgggaact
     8101 gaccaagtca tcacctatga cctcgatcaa gaaggaaaat tatctaagct ctatacctat
     8161 cacagcaagc caggagcagg ctcacgccat atcattttcc ataaccacta taaaatcgct
     8221 tatctcattt gtgaactcaa tagtactatc gaagttttaa tctacgatgg cgttggcgaa
     8281 tttgaacgta tgcaggtcat ttcaacttta ccggaagctt acgaaggctt taatggaacc
     8341 gctgctattc atctctctaa agacggtaaa tacctctacg cttctaaccg tggccatgat
     8401 tctatcgcag tatataccat ccttgcggac ggtagcttag agttattaga aatcgttcca
     8461 acgcatggtc agactccacg tgattttgat ttgacacccg accaaaaatt tctcattgtt
     8521 gtccatcaag actctgacaa tgcaactgtc tttaaacgta attgtgacaa tggtcgtcta
     8581 gcagaactct ccaacgactt ccatgttccc gaagcagtct gcatccgttt tgctccttaa
     8641 aacaccataa aaaatgaact tggtattttc aagttcattt tttcttatag tctatttccg
     8701 acattaatac ggttaatagc acgttgcaaa gcaatcttag cacgacgttc ttggtcaatc
     8761 aaatgtttgt cttgtgcttc ttcaattgca cgttctgcac gaagtttggc acgttctgca
     8821 cgactgatat cgatatcacg agcacgttct gcagagtcag cgacgattgt gatcatatca
     8881 ttggcaattt caataacacc accgtttact gcaatccagt tcacttgatc tttatcatcg
     8941 atacgtttta cctttacttc atcaactgct aaaaccgcaa tcatattttc atgtcgtggc
     9001 aagatcccca tctcaccatc cagagttcga accgatacat agctggcatg gtgatcatag
     9061 acgagaccat ctggtgtcac gatctggaca gttaactgag ccatagttca cctcttaaaa
     9121 tcccattttt tcagcttttg caatcacatc ttcgatagaa cctacaccac ggaaggcatc
     9181 ttctggcaag tggtcgtatt taccatcaag gatttcctta aagccacgta cagtttcagc
     9241 aactggaaca taagaacctg gctgaccagt aaattgttcc gcaacattga agttttgtga
     9301 caagaagaac tggatacgac gggcgcgagc aaccaaggtc ttttcttcat cagaaagttc
     9361 atccatacca aggatagcaa tgatatcttg caattcatgg taacgttgaa ggacacgttt
     9421 tacttcagca gcaactgcat agtgctcttc tccaacgatt tcaggtgcca aggcacgtga
     9481 gcttgaagca agtgggtcaa cggctgggta gatacccaat tgtaccaact tacgttccaa
     9541 gtttgttgtt gaatccaagt gagcgaaggc tgttgctggc gctgggtcag tatagtcatc
     9601 cgctggcaca tagatagcct ggatagaggt tacagaaccc ttcttggttg atgtgatacg
     9661 ttcttgcaat tgacccattt ccgtagcaag tgttggttgg taaccaacgg ctgatggcat
     9721 acgacccaaa agggcagata cttctgaacc agcctgagtg aaacggaaga tattatcgat
     9781 aaagagaagc acgtcttggc cttccacatc acggaagtat tcagcgattg tcaaaccagt
     9841 aagggcaaca cgcatacgtg ctcctggtgg ctcattcatc tgaccaaaga ccatggctgt
     9901 tttctcgata acgcctgatt ctttcatttc ccagtaaagg tcattcccct cacgagtacg
     9961 ttccccaaca ccagcaaata ctgaaatacc accgtgctct tgggcaatgt tgtgaatcaa
    10021 ttcttggatt aagacagttt taccaactcc ggcaccaccg aaaagtccaa ctttaccacc
    10081 tttaaggtaa ggggcaagaa ggtcaataac cttgatccct gtttcaagga tttcagaaga
    10141 ggtagacaac tcatcaaaag ttggagcttt tttatgaatt ggctgacgct ctgcgtcttc
    10201 tgtaaaagga gcttccaagt caatggtatc tcccaaaacg ttgaagacac gtcccaaagt
    10261 ttctttacct actggtacag agattggacg acctgtgtcc aatacttcca ttccacgagt
    10321 caacccatct gttgattcca tggcgatagt acgaaccata ccatctccta actccaaggc
    10381 tacttcaagg acgatttttg tttttctttc gtcatttttg tagacgacaa gtgcattgtt
    10441 aatctcagga agtttttccc ctgctgcaaa caaaacgtct acaacgggac cgataacctg
    10501 agcaatttta cctgaactca tctccttctc ctattctata taagatactg tcggttccta
    10561 gctcaactag gtcctaagtt cattttcata cgagctggac tagagcctat tctaaggcac
    10621 tagcacctgc tacgatttct gtaatttctt gtgtaatcgc cgcctgtctg gcacggttat
    10681 actgaattgt caaatcattg atgactttct tagcattatc tgtcgctgtt tgcatggctg
    10741 tcatacccgc agcattctca gctgtcttgg catctataat ggcaccgtaa atcatacttt
    10801 ctgcaaactg aggcaacaac tgctccagaa tttcttctcg gctggtttcc aattcaaaag
    10861 tcaagctgta ctcttcatcc gcttcatttg gatccaagtc aacaatcgga agcatttgtt
    10921 ccacacgcat ttgactggtt agcgtattga catggtggtt gtagcaaaca taaagctcat
    10981 caaagagttc attttggtac atttcaacag tttttgaaat aatcttacga acttgatcaa
    11041 agctaggttg gtctgccaag ccacgtaatt cataaagtgg ttgaataccg cgagccttaa
    11101 agaaatcagc tcccatccca ccgatacaga tcatttcaaa acctttaccg tctgggtggt
    11161 attcttcttt caactccata acagctttca aaatagagga attataacct ccaaccaaac
    11221 cgcggtctga agtgataacg atatagcctg tcttcttcac agaacggcta atcaacatcg
    11281 gattagttga agcaccagct ccattaccat gaaggatatc tgtcaaaagt ttacgcactt
    11341 tctgagcgta aacttggaag ttgcgagcag cttcttcaga gcgacctagc ttagcagccg
    11401 ataccatttg catggcatta gtgatttgac tcgtattttt tgttgaggcg atttttgttt
    11461 taatatcatt tagagatact gccatctgac acctctattc ttattggaag ctagattgat
    11521 tgagaaactc tgtaatcgca gcatccaaga ctgcttcttc tggcaagtct tttgtatcac
    11581 gaatggtttc caaaatctct ggatgttgag catcaaagaa ggcatggaac tcttcctcga
    11641 aacgaacaat atcatctact ggaacagtat ccaagaaacc atgtatcaaa gcataaagaa
    11701 tggttacttg tttctcaaca ggtaatggtt tgtgaacagg ttgtttcaag acctcaacgg
    11761 tacgacgtcc acggttcaac ttagcctgtg ttgctgcgtc caagtcagaa ccaaacttag
    11821 taaaggcttc caactcacgg tatgaagcaa ggtcgatacg aagtgtacca gcaaccttct
    11881 tcatggcttt gatttgtgca gaaccaccta cacgagatac agatgaaccc gcatcgatgg
    11941 ctggacgaat acctgcattg aagaggccat cgccaaggaa gatttgtcca tcagtgatag
    12001 aaatcacgtt ggttgcgata taggctgaga tatctcctgc ttgtgtctcg ataaatggta
    12061 gggctgtaat tgatccacca ccaagttcat cagaaacttt agctgagcgc tcaagcaaac
    12121 ggctgtggag atagaaaaca tcccctggga aggcttcacg acctggagga cgacgaagca
    12181 agagcgacag ttcacgataa gctaccgctt gttttgatag atcatcgtat acaatcaaaa
    12241 catgcttacc ttgatacata aattcttccg ccatagcgac cccagtataa ggagctagga
    12301 agagcaatgg agatggttgt gaagcagagg ctgtcacaac gattgtgtag tccaaggcac
    12361 cgtactgacg aagtgtttct acttgcgtac gaactgttga ttctttttgt ccaatcgcga
    12421 cgtagataca gatcatatct tgatcttttt ggttcaagat tgtatcaatc gcaatggttg
    12481 ttttccctgt ctgacggtca ccgataatca actcacgttg accacgacca atcggtacaa
    12541 gggcgtcaat agctttcaaa ccagtttgca atggttctga aacagactta cgttgcataa
    12601 caccaggagc tggtgcttct actggacgag ttttatcagt gtggatttct ccaagaccgt
    12661 caactggacg accaagcgga tccacaacac gaccaatcag actttcacct acagggactt
    12721 ccatgatttt ccctgtacgg cggattgtat cgccttcacg gatatctgta aagtcaccta
    12781 ggatgataat accaacgtct gttgactcca agttttgagc cataccataa gagccgtttt
    12841 caaaattcaa caactctcca ctcatgacat tttcaaggcc gtgagcacgc gcgataccgt
    12901 ccccgatata ggttacaaca cctgtttcag tcacatcaaa attgggtttg aaattttcaa
    12961 tttgttgctt aattaaagcg ctgatttctt gtgcgttaat tgccaaaaga acaccacttt
    13021 ctatttcaaa ttttctttaa caactttaag ttgttgttta atactcacat caattgtctt
    13081 gtgattggca aaaatgacaa aaccaccaat gagactttca tcgatttgtt cttttacact
    13141 ccttactttc agagacattt ttttctcaat caaagggagc aaacgagtct tctgttcatc
    13201 agttagagga tgagcagacg taatcgtcac ttcaaatcga tttgtttctt tttcaagtcg
    13261 gttcaagcaa tctacaagca catcataaaa aagatttgct ctgtgattgt aggccagaac
    13321 ctggataaag ttttgtaata aaggcgacac agaatcttgg aaaaaagcaa ttgttttttc
    13381 cttatccgac tcgtctactg ccacttgttt taaaaaagaa ggcagacctg ttttttcaac
    13441 aacttgcttg atttgagtca agtctgaaaa gatacggtct tcttctcctt tttcaagtac
    13501 caattggaca aaaggcatgc tgtatttttc aattaccttt actgttttct tgtccattaa
    13561 gcttctccta gctgatcgat atactgatca atgagtgctt tatgggcatg actgtcaagg
    13621 ttttgtgaga tgattttacc agctaagctg atggtcagat ctgcgacctc acccttaaca
    13681 ctctgtaaag cttctacttt attttgagca atttcttgat tggctttttc ttttaagtgt
    13741 cctgcttcta gtttagcatc tgctaagata ttagccttac tttgctcagc tgtttccttt
    13801 gcattttcaa tgattgtctt agcttcttta cggctaccag ccaattcatc ttcgcgtttt
    13861 tgagccaata cttctgcttt ttgacgggct tcttcagctc tgtcaatatc tgaagcaatt
    13921 ttttcagctc tttcttcgaa aatgcctgta atattagacc atgcaaattt tttaatcaag
    13981 actagcaaaa gaataaaaga gccagtgatt aaaataaaat taccaattaa ttcacctact
    14041 gttacgtgca tcagttactc ctttctattc ctcttcaata ttaatcttat tccctaaata
    14101 cacagatgtc aaaagagtaa aaacataagc ttggatgcag gaaataaaga cagaaaatgc
    14161 agtccaagcc aaattagctc caaaggctac tggataccaa taaatagctt ggtgggaaag
    14221 aagaagtaac aaactcgtca tgacctctcc tgcaaagata ttcccaaaaa tccgcaaagc
    14281 caaagataag aagtttgtaa attcttccaa gatattcatc ggtatgacaa aaacaggact
    14341 cataaaagat tttatacttt ttttaaatcc acgacgacga acgctttcta tatgtgtcaa
    14401 caaaatgaca agaaaagata aggttaagtc atactgtaaa ttagcggttg gcgaactcca
    14461 ccagttagtc ccatcgatcg tttgaagctt tgtcattaag ccaaggttat tggcaatcac
    14521 catgaaaagg aataaacaaa ggaaaaagag tgaataatct ttcatgtagc gcgaaccaat
    14581 gttaggttct gtaaatccaa taacaaagtc atagacatac tcaagtacat tttgctttcc
    14641 tttgggtttc aaggtcatat tgcggcttgc ccaataaata aagacaaaaa taactcccac
    14701 aatcaacaaa gtcatggcta acatagtcag attgaagata acaggaccaa tagagatgat
    14761 tggattaata ctttcttcca tctaaaatcc tcccttttct tctcgttcca tgtatttatt
    14821 tgataataaa tgagaagaca agagttacaa agaaagttcc ttcaataaag gcaacaccta
    14881 aaaacatcaa actacgaaac tcagaaagca tatctggttg gcgtgctact gatttaaaca
    14941 gtccattcat caataaacct tcaccgacag atacgcccat acaggcaata cataagccta
    15001 aaaatgttaa attcataaca aattctcctt taaaataaaa tttacttact tagtgtagtc
    15061 ctaaaattta aatttgtcaa cttttaaccg ctattggaag cgtttaataa aaattatttc
    15121 cattttgcta aatttcaagt tcaagttagc catcca
//
LOCUS       DAVBEM010000048        15154 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVBEM010000048 DAVBEM010000000
VERSION     DAVBEM010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15154
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.048"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(62..859)
                     /gene="proC"
                     /locus_tag="VQ548_001663"
     CDS             complement(62..859)
                     /gene="proC"
                     /locus_tag="VQ548_001663"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HET2654476.1"
                     /translation="MKIGFIGLGNMGASLTKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            complement(863..2125)
                     /locus_tag="VQ548_001664"
     CDS             complement(863..2125)
                     /locus_tag="VQ548_001664"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HET2654477.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAVSFLPRLEQ
                     VLVADRKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            complement(2135..3265)
                     /locus_tag="VQ548_001665"
     CDS             complement(2135..3265)
                     /locus_tag="VQ548_001665"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HET2654478.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMVEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRFQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(3348..5228)
                     /gene="cbpE"
                     /locus_tag="VQ548_001666"
                     /gene_synonym="pce"
     CDS             complement(3348..5228)
                     /gene="cbpE"
                     /locus_tag="VQ548_001666"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HET2654479.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIDGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTGGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SE"
     gene            complement(5231..6118)
                     /locus_tag="VQ548_001667"
     CDS             complement(5231..6118)
                     /locus_tag="VQ548_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2654480.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(6108..6569)
                     /locus_tag="VQ548_001668"
     CDS             complement(6108..6569)
                     /locus_tag="VQ548_001668"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HET2654481.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMFLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(6566..7474)
                     /locus_tag="VQ548_001669"
     CDS             complement(6566..7474)
                     /locus_tag="VQ548_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET2654482.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            7467..7664
                     /locus_tag="VQ548_001670"
     CDS             7467..7664
                     /locus_tag="VQ548_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2654483.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(7716..8387)
                     /locus_tag="VQ548_001671"
     CDS             complement(7716..8387)
                     /locus_tag="VQ548_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2654484.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(8441..8662)
                     /locus_tag="VQ548_001672"
     CDS             complement(8441..8662)
                     /locus_tag="VQ548_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HET2654485.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            8934..9743
                     /locus_tag="VQ548_001673"
     CDS             8934..9743
                     /locus_tag="VQ548_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2654486.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(9924..10799)
                     /gene="aguB"
                     /locus_tag="VQ548_001674"
     CDS             complement(9924..10799)
                     /gene="aguB"
                     /locus_tag="VQ548_001674"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HET2654487.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKLLAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYNLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(10809..11894)
                     /gene="aguA"
                     /locus_tag="VQ548_001675"
     CDS             complement(10809..11894)
                     /gene="aguA"
                     /locus_tag="VQ548_001675"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HET2654488.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVV
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(11891..13018)
                     /gene="nspC"
                     /locus_tag="VQ548_001676"
     CDS             complement(11891..13018)
                     /gene="nspC"
                     /locus_tag="VQ548_001676"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HET2654489.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(13018..14277)
                     /locus_tag="VQ548_001677"
     CDS             complement(13018..14277)
                     /locus_tag="VQ548_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HET2654490.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMLD"
     gene            complement(14274..15134)
                     /gene="speE"
                     /locus_tag="VQ548_001678"
     CDS             complement(14274..15134)
                     /gene="speE"
                     /locus_tag="VQ548_001678"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HET2654491.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEYDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
BASE COUNT         4443 a         3505 c         2765 g         4441 t
ORIGIN      
        1 agtttgaatt tgattttcga agagtatcag ccaccataaa agaggcagat aaaactacct
       61 cttatttacc tagttcttgt gttcgtttat aggcttgatg aactgcctcc atgactgtgc
      121 ctcgaaaagc atgcgcttct aggcttgcta cgccagcaat agtcgaaccg cctggactac
      181 aaacttgatc tttcaaaact ccaggatgtt gctggctttc taggaccaat tgcccagctc
      241 ctaccacagt ttgggctgcc attttcaagg ctgtttctcg tggtaatccc gtctgaacac
      301 ctgcatctgc caaggcctca ataaagagat agacaaaggc tggtccacaa cctgcaagac
      361 ctgtcgctgc attgattaag ctttctccta attcaaccaa gagaccagcc ttggctaaaa
      421 gctgacaaaa gatctcactg tcctcagccc tgcaattagg agacaaggca taactaatca
      481 ctccttgccc gatagaagca ggggtattag gcatcatacg aataattcgg tgttggcttg
      541 ggataagact tgctagtttt tctaaggtca atccagctgc catcgaaatc aaaagaagac
      601 tttctctttt ttcaaggatg gtctggtatt gagaaagcag ttcagaaaac tgagcaggct
      661 taacacctag aaaaatcaca tctgcttctt cgaatatttc ttcattgtta gaagtctgac
      721 caccgaagtt agcgatgaaa gcatccacct tgacttgact acgattggca aggagaatct
      781 catctgacgg tctagcctgc aagacagact tggttaaact agcacccata ttccccaaac
      841 cgataaatcc aatcttcatc tcttactccc ttatctgtcc atcaccagtg accacatact
      901 tgtagctagt caattccttc aagcccatag gaccacgcgc gtgcaatttc tgagtagaaa
      961 tccccatttc acaaccaaga ccaaattgtc ctccatctgt gaaacgagtt gaggcattaa
     1021 catacaccgc tgcagagtcc acttgatctg taaagtatgc tgcagcttca gcattttccg
     1081 tcacaatggc atccgaatga tgggtactgt gggattcaat atgcgcaacc gcttcttcta
     1141 aactgctcac aaccttaaca gctagaatat agtctaaaaa ctcggtatca aagtcttgtg
     1201 cttgagcagc ttgacctgaa acaaactggc ttgctttgct atctaggcgg aattgaattg
     1261 gttccaaccc agcttctttt cgatctgcaa ccaacacttg ctccaagcga ggaaggaagc
     1321 ttactgcttt gttttcatga accagcagaa cctccatggc attacaaaca gaaggacgac
     1381 tggttttagc attgttgatg atagacagcg ccttgtcttc gtctgcatcc ttatccacat
     1441 agacatggac aatcccagtt cctgtctcga taacaggtac aatcgcattc tcaaccactg
     1501 cattgatcaa gccagctcct ccacgaggaa tgagaaggtc tagatagccc ttggccttca
     1561 tcatagcata actactttca cggctagtat cctccaccag ttgaatcaca tttggatgaa
     1621 tagtagtcgt ctccaagccc ttcttcaagg ctgtgacaat ggcatgggtt gtttgatagg
     1681 catccttacc actacgaaga acaaccgcat ttccactctt aagagtcaaa gcagccgcat
     1741 cagacgtcac atttggacgg ctttcataga taataccgat gacacccata gctacacgtt
     1801 tttttgtgat aaccaaacca ttttcaagct gacttgtttc taaaacttca ccgattggat
     1861 ctggtaaggc aaccacttca cgaattcctc ttgccatcgc ttctatacga tctgcatcca
     1921 aataaagacg atccaacatc acatctgaga ttttcccctt agccgctgcc atatcgaggg
     1981 cattagccgc taaaatttcc tcagtagcag ccactaagtg atcagccatg gctagcaagg
     2041 cttggttttt cacttcttca ctagctgtgt taatcgattt tttaacagcc tgtacctgtt
     2101 caaattgttc ttgtctactc accatagttt acctctaaaa ttctgtaaaa agtagttgga
     2161 tttcaggagt aatggaaatc cagtcgtcac ggtaaatcaa gacacccttg gctttttgaa
     2221 aacgcaacat atcctccaaa gcagatgctc caaattgcac gcgtcctttt ccaagtgatt
     2281 ttccactttc cttatcaaat actgtcacga tatcaccgta agaaaagact ccttctgctt
     2341 caacgatacc agataagaga agactctttc catgttgaga gagagcttcc gcagcccctt
     2401 tatcaaccca aatagaacct tgactctgag catagaaggc aagccattgt ttctgggtac
     2461 gaagcccctt ctcttgagca acaaagtaag aaccatcctc ggtctcctct gccgcctcaa
     2521 ccatggaatc tgatttcaag gatgagcaga tataaacagg aactcctgat tccgtcgcga
     2581 tagttgcagc cttgattttg gttaacatac ccccagttcc gtttgacgaa ccagctccac
     2641 cagccatatc aataatctca cgattgatgg tctcgattct ctccaagcgt ttggctcttg
     2701 gatctgaatt aggatttcca gtatagagac cgtccacatc tgtcaagaaa actaaaaggt
     2761 ctgcttggac catcgccgct acttgagcac ttagagtgtc attgtcccca accttgagct
     2821 catcaataac gacactatca ttctcattga tgataggaat tgccccacgg ttgagcaaaa
     2881 ccgacaaagc ctgatgggca tttttataac gacgcttatc cacaaagtca tcttgggtca
     2941 gcaagatttg tgcagaaacg atttgacgca agagaagatt ggtcgtatat tcttccaaca
     3001 aaagtccctg ccctaccgct gctgaagcct gtttatcagc aattttagtc ggacgctttt
     3061 taaatcctaa ggctccaaaa ccagccgcaa tggcacctga agacaccaaa atcaactcat
     3121 gaccagcctc gtgcagcata gccaactgct gggtaatatc ctttacctta ctacgtgata
     3181 aacttccatc ctcatttgtc agagaagaag tgcccacctt aaagacaatc cgtttgtatt
     3241 tcatagtctc actccgatta ttcatattta tccattataa catgaataac aggaaataga
     3301 aaagagttga taggaaaaag aaggccctaa aaccttcttt tctactacta ttctgattcc
     3361 gatttgttta cactcgtttc agagctttgt gaagttgagg atgtcaaatc ttgactagtt
     3421 gaagaatttg taacactttc atgttgactc gtttctttat tttcaagatc ctttttcact
     3481 acttctttgg attcttttat ttctgaatga cttgtagttt taattgtagc agatttctcg
     3541 atcggaacat ccactaacca ggcaccactt gaatccacag tatagccttc tggtgtctta
     3601 ccattcacaa gtaattgacc attttctttc aagaagtacc atttatcctt gtctttaatc
     3661 caacctatag ctcgtgaacc acctgtcttg tagaaatacc aatcatttgc ctttttaagc
     3721 cagccttgct tcatagctcc tgattcttct agatagtaat gatgtccagc aacttctatc
     3781 tcacctgtct tcatgatacc agtagaatcc atatagtacc aggcttcttt atcttttacc
     3841 cagcccgttt tcatttcccc tgatggagca aagtaatacc attgcccctt atattgaagc
     3901 caacctgtct tcatagagcc atcaacatcc aaataatacc actgctcttt atcttgaacc
     3961 caaccaattt ccatctgatt ttctttgtta aaataatacc agattccatc aattttcttc
     4021 caatttttag cagaagcacc agagtctgtc aaatagaacc aatgattgtt ccattttttc
     4081 cattgattct gtaacaagat acccgtttgg ttaaagtaat accattcacc ttcgatttca
     4141 ttccaaccga cagcatactc tcctgtagaa tcaggcgctt gataccacca gttcccatat
     4201 gcactcttat gccaaccagc ttgaaaactt ggaatcggct tgtaggatgt tgaaatattg
     4261 acaaaaccgt cttttcgaat atcaaaaact gttgcatcat agtctttgct ggctgcgttg
     4321 attctctcaa ttcctcgttc tttgagccaa ttaacatact cactatcaac accatttttc
     4381 caaggtagac tatccgaagt ttgaacaatc aaactcggac tcaaattttt aatgaaatcc
     4441 ttggtatttg atttgttggt atcatggtga tgattaaact tcatcaaatc aacttttcca
     4501 atgagaggac catacttgtc ttctgctcca tgaacattat ctaaatcgcc cccaaggtaa
     4561 attttcttgc cattgacttt caccacgcta atcaaggaat tggaattgtc atcccaaatt
     4621 ttctttaatt cacccgatga atcagtttca ttttcataat tatagagctg aatatccatg
     4681 tccccaaact gaaaatgagc atccccttgt gtgatatttt gaataactga aacacctttt
     4741 tctgcagcag tctgtaaaac cttatcatag ccatacagat tatcccatag acgttcagaa
     4801 ttagtaatac gactatcact atatttctta agatagactc ggtcaactgg ataggtagac
     4861 agtaattcat caacatttcc aatatgatca ctgtgggtat gggtcaccaa aataaaatca
     4921 agtttttgga cacccaattc cttcaaacga cgaaagacac ggtctgttag aacatgctta
     4981 taagacgttt caattccttc tctccatgga taacgagaat cacttccatc tgggaaatca
     5041 taatcttctc ctgtatccac catggcaaaa tgtccattgc tttcaagaat aatcgcatca
     5101 ctgccacctt cttgaacatt gataaagtgg attttatttc ctgaactttc ttgagcctga
     5161 acattcccat accatgacaa acctaaaaaa gcgcctacaa gtgctaaact agttaatttc
     5221 tttttcattc ttactttctc aatctctcca aggtttcctt aaaaatctct gggatatctg
     5281 ctttaaattc caaggtctta cctgttctcg gatgagtaaa acctaaagtc ttggcatgaa
     5341 gaaattgtcc atgtcctttc aaagtcttgc gaggaccata gacctcatca ccagcgactg
     5401 gatggccgat ataagccatg tggacacgga tttgatgagt gcgccctgtc tccagttgca
     5461 actctactaa gctataatcg ccaaagcgtt ccaagacgtg aaaacgcgtc actgcaggct
     5521 tccctttagc agttacagcc tgtttcttac ggtctttttc actccggcca atcggcgctt
     5581 caattacacc acgatcatta ggcagatttc catgaacaat cgcccaatat ttgcggagag
     5641 actttttatc tttgagttct tgggcaagta ctagatgcgc atcatcgttt ttagcaatca
     5701 tgagaagacc tgacgtatcc ttatcaatac ggtgaacaat ccctggacgc agaaccccat
     5761 tgatacccga caagtcctta atatgataca tgagggcatt tactagggtt ccactggtat
     5821 gaccagcact cgggtgcaca accattccct gaggtttgtt aacgacagcc acatcctcat
     5881 cttggtagac tatttctagc ggaagatcct cagccacata ctctaatacc tctggttctg
     5941 gcacatggta agtgacgaca tcaccctctt ggactgtgta tttagctttc ttgacttgac
     6001 cattgaccaa gacctggcct gatttaattt gttcattcgc gagactacgt gataattctg
     6061 acaaatctga caaagcctta tccaaacgca gaccaccagt ttcaatttta atttccattt
     6121 atttcctctt ttagcattgc aatcaataaa ataatcactc caaccgtcag atagctatct
     6181 gccacattga aaattgcaaa gttgataaag tcaaggtgga acatatccac aacaaagccc
     6241 tgactgaccc tgtcaataaa gtttccaaga ccacccgcga ttattagagt caaacccaag
     6301 aacatccaga atgagtcctc catgtgttta tgtaaatacc aaatggcacc tatcacgaca
     6361 accagagtaa tgacagcgaa taacagctgc tgatcttgta agatagaaaa ggctgcacct
     6421 cgattttgca ggtaggtcaa gctaacgaaa ttgggaatcc aggagcgcac ttcacccagt
     6481 ggaatctgct ggacgatata ggatttgacc aactgatcca gcccaattaa aagcagtaca
     6541 atgactgcca ctattgctct ttttttcatg atttcctctt ttgatcaaaa tattcttgca
     6601 tgacttctac gaagagagtc ccagcttgac taagctccac ttcttcacgt ttaacataga
     6661 ccatgcggtt atctaggtta tccttgagac gaataactgt aatgccatta acactgtcac
     6721 tatctaaaaa tccagaacct gtcgcatagg cgtccgtccg ctccaaaata ccattcaagg
     6781 tggcacggtc tgtcacatta aacatctgtg agctagcgct ggtatcgaca aagttctctg
     6841 aataataaag gtactcgtct ttctcttgag tgaaacgaac cgttggtaaa tccgctaaat
     6901 cctccatgac taattcctct ttctgggcta aaggatgacc ctcacagaga taaatatggg
     6961 tatggaaagg aatcaattcg atgacctcca gacctaactt ttcaacccgt tgcataatcc
     7021 cctttttatt ttgattgttg aggtagataa tcccaatctc actatgccct tgcgccactt
     7081 catctaatat ttgaacagta gttgattcaa aaatacggaa gttcttatag tcaggatagc
     7141 gctctgaaaa ggccgtaata gttggtggta agaagtcata gtgctggcta gcaacggaaa
     7201 attcatcttt ttcttcttca ggattggcat actgattttg aaaaatatca aatcctttaa
     7261 ccaattcttg cgctttttca taaaattcca tcccacgacg ggtcaagaaa gtccctgagc
     7321 tggtccgacg gaaaatctta aagcccaact ctttttccaa atcacgaaca gaaatagaca
     7381 gactcggctg actaacatac atcttttcag cagcttcacg aaaagtacca ctattggcaa
     7441 tagccacaac atagcgtaat tgttgaatgt tcatcttcta cccccaactt ctttatcttt
     7501 tcattatacc atattttaga agttttccaa aaaggaaaaa agaacatcct attcttctta
     7561 actatcttca ctatctgcct ttctcacgcc aatcttattt tcaaaatcaa ttcaaaaaaa
     7621 taagtggcta cacaccactt cagtatcgga aagaaaaacg ttgactattt gtgaaaaaag
     7681 aaaatgccgg aaaattccga cattttttta gtaagctaac ttcctgaaaa taggagtaac
     7741 caaacatccc agaaggcagt gatattgatg agaatatgaa ctagtattgg atagtagaga
     7801 tttttagtca tgcgatacaa tagagctaaa atcagacctc cactagcata aatgaaaaaa
     7861 gcaagaggag ttaaagcaaa attgatatga atataaccga aaataatagc agaaagcaaa
     7921 acatctccgt accaaggtga gtttttgaaa aaggttgtca taagcacacc tcgataaatc
     7981 aattcctcag caataggggc gatgaagcaa acgatgagca agaaataagg gaactcctgt
     8041 ctccccatca tttctaccgt ttcattcaaa gaaatctgat ttgaagacag ggatatgaaa
     8101 tacgaaaaga ggaagtcaga catatatgaa atgatgtagc ccagtaaaag gtagatgaag
     8161 tacctcagct gccacttgaa atgaaaaatt ttctttcctg caaaaaccag tagatagatg
     8221 accgctaaga aaagaactcc gctctccatc aaaagcagaa tctgaaaaaa ttcacgactt
     8281 gctggtagat agggctttgc gaggtgattg aaaactctcc aaaaccaagt tgatttgtaa
     8341 aaaattaagg acaatgctag taaaatttga atagcccgtt ttttcatatt aaattctctg
     8401 ctttctccac ttatttcttc atattactaa taaattttac ttaaaatctc gcagcacttc
     8461 ctttgcaaag atgattgcct cctccaatat atcctaaatc ataggtgcct ctgggacaaa
     8521 atccatgaac cggcagagtt aatactggtt ctatttccca atcgtaccta ccattaggat
     8581 ttttaccata tgaatctgct ccaccttgta tcagctctaa ttcttcattt gttagattta
     8641 tattttttgt cattaaaatc atgatatatt tcctccatta ttcttcagat tagttgagta
     8701 atctgatact catacctact tacaaaaaaa ctattatatt aagttggttt tttaatttgt
     8761 ctagttgcaa cattgacaaa catagtatag catatctttg cgaaatatcc tcttcaaatc
     8821 atgaattgtc atcaaaacat cttaaactat aaaatcaatt agtctcaagc tttctatcaa
     8881 tttcttctcc aaaatatgct ataataatag caaaagataa agaaggaaga cctatgatta
     8941 aactactagc cttggatatg gacggcaccc tcctcaatga agccaaggaa atcccacaag
     9001 ctcacattac tgctattcac aaagccattg aaaaaggtgt caaactggtt ctctgtacgg
     9061 gtcgccccct tttcggtgtc ctcccctact acaaaaaact gggactcgac ctccagaatg
     9121 agtatgtgat tgttaacaac ggttgttcaa ctcaccagac tagcgactgg ggcttggttg
     9181 actggcaaga acttagtcca gctgacatcg aatacctcta tgaccttgct gaaaagagtg
     9241 atgttcagtt gacacttttt gacgagtcac attattttgt tctcggtgga aagcccaatc
     9301 aagttattga aaatgatgct aaactagtat tttcagacct gactgaaatt tctcttgagg
     9361 aagcgactag tggaaagttc cggatgttcc aaggtatgtt tttaggaaca aaagaacaaa
     9421 cagacgattt tgagcagcgt tttgctgaag agctttgcca acgattcagt ggagttcgtt
     9481 cgcagcctgt catttatgaa gcaatgccac ttggaacgac aaaggctact gctctttcac
     9541 gactagctga gattttgaag attgattcct cagagattat ggccatgggc gatgctaata
     9601 acgatatcga aatgctccag tttgcagggc ttgggattgc aatgggaaat gccagcgatt
     9661 atgtcaaatc tcttgcggat gccgttacct caagcaacga agaagacggc gttgcgcgtg
     9721 ctattgagaa atatattcta taaaaaagaa aagcaaatag acagaagtta ctgctatttg
     9781 cttttttgct aatattttaa aatacggact aatcaataga gaagaatagc gaatcataaa
     9841 aatcgattta ctagatgcca tagtatctta tagttgctaa taagaagtta gtctagcaga
     9901 atgaatctct catttctccc acactaatct gtaatttgtc tatacatttc tggtcttcta
     9961 tctcgaaaca agccccagtt taggcgttca cttgctccct tgtctaggtt ataagtagct
    10021 aacagaacag cttcttcttg tctttcagct cgttctagaa tagctcctgt ttcatccgtc
    10081 ataaaggagg aaccgtagaa gtcaagactg gaactctgtc cgccattttc ctcactagga
    10141 gtaacctcct ctaaaccata acgattggct gcgatgactg gaacaatatt cgctgctgcg
    10201 tgcccttgca tagtacgttg ccagtgacca caactatctg tatccaaaat tggctctgaa
    10261 ccgatagctg taggataaaa gagcaattca gcaccattca atgcaagaca gcgcgctgtt
    10321 tcagggaacc attgatccca acagataccg ataccaatct tagcatagcg agtattccag
    10381 accttgaaac cagtgttacc aggcgtgaaa tagaattttt cttgataata atggtcatct
    10441 ggtatatggg tctttcgata aacgcccagc acttccccat ctgcatcaat gacggcaata
    10501 gagttataca agacattacc atctttttca tagaaactga ttggtaaaac aacttgtagt
    10561 tccttagcaa gcaacttaaa atgctgaatg gcagtatttt ccgctacaga ttgggcatac
    10621 tggtagtagt catactgacg ttcctgacag aaatagggat gttcaaacaa ctcgggcaag
    10681 agaataattt gggctccttg ctcagcagcc tgacgtacta aacgctctgc ggtttggata
    10741 tttgttgcca catccttagc gcattgcatc tgaatggttg caactcttac atttctcatc
    10801 tttttctcct attctggaat ttgttgggtg atacagtgga tattgccacc acctaagaga
    10861 atatctctgg ctggtattcc gacaacttta cggtctggga aacacttgct gaggatatct
    10921 aaggccactt ggtcgtttac atcctcaaac tgtggaacca agacagcctt gttggcgata
    10981 taaaagttta cgtaggaagc tgctagtcgt tcacctgcgt atcgctcttc ttctccttct
    11041 tcatagatgt agcctggcaa atcttcttct gtcacaactt gtcgaactgc agggataggc
    11101 aatttatgaa tggtgaagtg acaacctttt gcatctgttt cctgttctaa gagttcgaga
    11161 tctgcttttg acatggcata ctggggatca ttttcgtcat ctgtccaagc caaaacaacc
    11221 tcagcaggac caacaaaggc aacaacatta tcgacgtgtt cattggtttc atcctgataa
    11281 ataccataag gaagccaaat aactttttca gcaccaagac tttctaataa tgtgttttca
    11341 atctcctctt tagtcaagtt aggattgcga ccaggactaa gcaagcaact ttcagttacg
    11401 agaatagttc cttgaccatc gctatggatt gcgcctcctt ccagtacaaa aggtttagca
    11461 tcatagacag gcctttccaa ggcctcagca aaacgactgg ctacttggtc atcctcttca
    11521 taatcttgat aaagaccatc ataggtgcct ccccaagcat taaaggccca atccacggct
    11581 aatttcttac ctttatcatt gacgagaatg gttgggccag tatcacgcgc ccaggcatca
    11641 ttggtgggaa tgtctaaata aacaaccttg tctccaagat aggattgggc ttcagataga
    11701 taggcctgct ccaccaaaag atagactctt tccccttctg ctatggtctc gatgatctga
    11761 gtaaatgctc ttttagcagc ctttccttga aaaggccatg atcctggtcg agtcggccat
    11821 atcatgaggg taccatgatg gggttcgtac tctgctggca tgtgatagcc taattttttt
    11881 ggactgtcca tcatgataat ctccctttaa agtcttgata gccaaaagct ttgagtaagc
    11941 tacagtctcc ctgttcgtcc atgagataga gacttggcaa tccaatacca ttaaaggtat
    12001 tatttttgac aaaagaataa atggccatgt cttgaaaata aagtctgtct ccgatttgga
    12061 ctggattttc aaaactataa tcaccaatca catcgccagt cagacaggta ttagaagaaa
    12121 gtctgtaggt atgggctttt tcctgtgact caaagccatt tctcaaaggt ggacgatagg
    12181 gcatctcaag tacatcaggc atatggcagg tcgcagaggc gtctaaaacc aagatttcca
    12241 taccgttttc tacaatatct aatacctcag ttgctaaata acccgcatta agcgcaatgg
    12301 cttcaccagg ctcgatatag atttcaagat tgtaagtttt tcggatacgc ttgatttctg
    12361 aaatcagcaa atccacatcg taaccttctc ttgtaatatg atgaccacca cccatattga
    12421 gccattttac ctcatgtaag tagggaccaa actgttcttc tactgctttc aaagttgttt
    12481 gtaaatcatc tgctccctgc tcgcaaaggg tatgaaaatg aagtccgtca accaaatcta
    12541 gcaaatcgct cggaatcttg tctatagtaa ctccaaagcg agaaccaggt gcacaagggt
    12601 catagagcgc gtgatctcct tgagttgaac actgagggtt gaggcgcaaa ccaacactga
    12661 caccagcctc tcgacaacga gccccatgct tacgcaactg tctctctgag ttaaagacga
    12721 tatggtctgt tatcccaagc aattcctcca tgtcctcatc cttgaaagct ggtgcaaaaa
    12781 catggacttc accaggaaat tcttcccttg ccaatttggc ctcatagagt ccactagctg
    12841 tcgtacctga tagatactgg ctaatcaagg gataagtttt gtagagggaa tatgccttct
    12901 gggcaagcaa gaccttgcaa ccggcctctt cttgtacata ttgtagaatg cggcaattag
    12961 cttctaactt ggccaagtca ataacatagg ctggtgttgg tacttgttct aacttcatta
    13021 gtccaacatt tgtggatttt caaccacaac ccatggcaaa ccatactcat tcaaagcttc
    13081 catgaatgga tctggatcta actcctcaag gttatacact ccagcttgtt tccaagttcc
    13141 gttcatgact aattttgtcc caatcatggc tggaacgcct gtcgtgtatg aaattgcttg
    13201 tgacccgact tctgcatagc actcttgatg gtcgcaaaca ttgtagatgt agatagtctt
    13261 ttcaacgcca tctttgacac ctgtaaagat acatccaata ttggttttac ctacagtacg
    13321 tggaccaagg ctagcaggat ctggaagcaa ggctttcaaa aattgaattg gaacaatttc
    13381 ttggccgtta aagttaatgg tatccgtacg aaggagtcca acattttcaa gacatttcat
    13441 gtgcgtcaag taagattgac caaaagtcat aaagaaacga atgcgtttga cacctggaat
    13501 gttcttggcc aatgattcga tttcttcatg gtgaaggaga tacatatctt tttgtccaac
    13561 ttgagggaaa tcatactcac gcttgataga catagcttcg acttcgaccc atttcccatc
    13621 ttcccagtaa gaacctggcg cagaaacctc acggagatta atttctggat taaagttggt
    13681 tgcaaatgga taaccgtggt caccgccatt acagtctaaa atgtcgatat aatggatttc
    13741 atcaaaatag tgtttgaggg cataagctga aaagacacta gttacacctg ggtcaaaacc
    13801 agaaccaaga agagcagtca agcctgcttc tttgaatttc tcttgataag cccactgcca
    13861 tgagtagtca aagtaggctg taaaaccaag ttccttacaa cgtttttcgt agatagcacg
    13921 ccactcaggg tcttctgtgt cttctgcttc gtagttggct gtatcgatat agtgaacacc
    13981 tgttgccaaa caagcatcca taatggttaa atcttgataa ggcagagcta cattcaaaac
    14041 agcttctggt ttgtagcttt caatcagagc aatcacttct tcaaccttgt cagcatcaag
    14101 agcagctgtc tcaatctttg tacttgtttt gccttccagt ttagctttca agtcatcgca
    14161 ttttgacttg gtacggctag caatcataat ctctgtaaat gtttcgctat cttgacaaat
    14221 ctttgaaata gcaacttggg caacgccccc acaaccaata actagtaaac gactcatttt
    14281 tttccttcct cttcttctaa aatgtcctca acatacttgg gcaacataaa ggctcccacg
    14341 tgtaagtttg cagtgtagta ttctgtgaaa agctggcgtt ttttccagcc ttccttgtca
    14401 aaatctttga cagggtggta ttttttcgat gcaaatccaa acaaccaata gccagctggg
    14461 ctagttggaa tatgggcctg ataaacccga ctgattggaa aggcttgatt gaccttgcgg
    14521 tgcatgcttc ggcaggccga ctcatcctcg tcaaagaacg gactcccatg ctggtaaatc
    14581 atgatgccgt cttccttcag agctcgataa ctattgccgt agaattcctt ggtaaagagt
    14641 ccttccgtat ggccaaatgg atctgtcgca tcgttgatga taatatcata gtcatattcg
    14701 cagtttcgca aaaagcgtag cccattttgg tagtaaatgg taacacgagg atcatctagg
    14761 cctgcagcaa agtctgggaa atactcacga cagacctcga ccaacatctc atccggttcc
    14821 acgatatcga tttgttccag ttcaggatag agtgttaata cttgggcaac accgccgtca
    14881 ccacccccaa taaccaatac tttctttgga tttgggtgga cagccatggg aacgtgaacg
    14941 gtcatttcat tgtagacgaa atcatccgca tctgagaaca agacatggcc atttaaaatc
    15001 agtattttcc caaaagctgg cgtatccaag acttcgatat cctgccattc actttttcca
    15061 gcgtaaagtt gcttggctgt tctcagagac aatttgacat ctggagtatg aacttcagaa
    15121 aaccataaat ccatctattt ctccttatat tata
//
LOCUS       DAVBEM010000049        14799 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVBEM010000049 DAVBEM010000000
VERSION     DAVBEM010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14799
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.049"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            <1..662
                     /locus_tag="VQ548_001679"
     CDS             <1..662
                     /locus_tag="VQ548_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654492.1"
                     /translation="IIRKVQEPEFWKEVNLSDLEKIRLAIRDLLQFLDKTDRKPYYVN
                     FEDRILSTVHETTAFLQVNDLRSYNEKVEHYLKTHLDEESISKLYHNKKLTSDDMLAL
                     EKLLWEKLGSKADYQSHYENKAIPRLVREIIGLDRESANRIFSKFLSDENLNARQISF
                     VKLIVDYIVENGFLETKVLTQEPFKSYGSVQLLFQHQLPVLRNIVQIIELINNRAGEA
                     A"
     gene            complement(1062..2408)
                     /locus_tag="VQ548_001680"
                     /pseudo
     CDS             complement(1062..2408)
                     /locus_tag="VQ548_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
     gene            2470..2664
                     /locus_tag="VQ548_001681"
     CDS             2470..2664
                     /locus_tag="VQ548_001681"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654493.1"
                     /translation="MSSKKHPLGEKRNHTGSKLRQGFWMVFRLGVNNWGFKEIENKKP
                     SKNSIAGENEIILNENQRAN"
     gene            2642..2842
                     /locus_tag="VQ548_001682"
     CDS             2642..2842
                     /locus_tag="VQ548_001682"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654494.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDKTDEVSSKHGFEVVDETDEVS
                     NHTYGKATLTRIEEIFEEYKSS"
     gene            complement(2922..3367)
                     /locus_tag="VQ548_001683"
                     /pseudo
     CDS             complement(2922..3367)
                     /locus_tag="VQ548_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3375..3518
                     /locus_tag="VQ548_001684"
     CDS             3375..3518
                     /locus_tag="VQ548_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654495.1"
                     /translation="MAERFWENLSIILADRNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            3611..4198
                     /locus_tag="VQ548_001685"
     CDS             3611..4198
                     /locus_tag="VQ548_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2654496.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCSDELTILQILYGASLIS
                     FLWMYGQRKQVIKVNMKTRIQWLGIGFVSLLIISLCFSLIHAQESTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWNLLVYSLLLF"
     gene            4597..5406
                     /locus_tag="VQ548_001686"
     CDS             4597..5406
                     /locus_tag="VQ548_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2654497.1"
                     /translation="MLLQKELIPMIEANLPNMAYAEKDIAKFFLKQQPLNNYSCKALC
                     ECLNVSKATLTRFAKKCGFKGFRQFIFKYQEMIREKEKLALYTEATEKVLSDYEEMLR
                     KTYTVLDEVQLERIAEMIETAERVYLYGKVSSVLALQEMKMRFMRLGVIGEVLSDEDM
                     ILWNSLLLNENCLVIGASVSGQTDIVLEGLQKAADKGAKTVLMTTRKFDEEDCFFDEL
                     LLLASTNHLSYGNRISPQFPILLITDCLFSHYLESPERQYYYNQTIIHKEE"
     gene            5411..6112
                     /locus_tag="VQ548_001687"
     CDS             5411..6112
                     /locus_tag="VQ548_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2654498.1"
                     /translation="MSQIWTKEKFISQVHGGVIVSCQALPGEPLYNEEFSLMPFMAKA
                     ALEAGAVGIRANSVRDIKAIQKVVDLPIIGIIKRDYPPQEPYITATMKEVDELVECGT
                     TVIAFDATLRPRYDGLVINEFIKKIKEKYPNQLLMADVSNFDEGLYAFKSGVDFVGTT
                     LSGYTSTSVQSDEPDFELMKKLADFNIPVIAEGKIHYPEQLKKAYSLGVTSVVIGGAI
                     TRPKEIAQRFINVIK"
     gene            6137..7054
                     /locus_tag="VQ548_001688"
     CDS             6137..7054
                     /locus_tag="VQ548_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HET2654499.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQERVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHVACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAAPNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            7082..8623
                     /locus_tag="VQ548_001689"
     CDS             7082..8623
                     /locus_tag="VQ548_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HET2654500.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGNSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGAVAIVYSYTGGLKSVLWTDFIQGVILISGVVLALFVLMANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLATATVFYLIGTGLYVFYQVQNAGSAASNIPQDQIFMYFIAYQLPVGITGL
                     ILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDDRRTKIAQFVSLAVGLFSIG
                     VSIVMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTGNKVSAPKYTTIHDIPEIKADSS
                     WEVRH"
     gene            8642..9100
                     /locus_tag="VQ548_001690"
     CDS             8642..9100
                     /locus_tag="VQ548_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2654501.1"
                     /translation="MIISEQSDFRRYASINKHFSKVCDFLENTNLTDLVDGKVDIDGE
                     NVFANCMIYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDEPVKKLVIKVLNEEK"
     gene            9102..11324
                     /locus_tag="VQ548_001691"
     CDS             9102..11324
                     /locus_tag="VQ548_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HET2654502.1"
                     /translation="MKKNIKQYVTLGTAVVLSAFVANSVAAQETETSEVSTPELVQPV
                     APTTPISEVQPKSGNSSEVTVQPRTVETTVKDPSSATEETPVLEKNNVTLTGGGENVT
                     NELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNHLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPVPLEWPRDVGGRDLQISGGATYIDSVIVEKNNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLKKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFKNNKKTEYRNGTHVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSTDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQIWIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            11364..12473
                     /locus_tag="VQ548_001692"
     CDS             11364..12473
                     /locus_tag="VQ548_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2654503.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEYEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            12630..13520
                     /locus_tag="VQ548_001693"
     CDS             12630..13520
                     /locus_tag="VQ548_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2654504.1"
                     /translation="MKIIGIDIGGTTIKADLYNEFGTSLNQFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYILNHSIDGVGISTAGVVNANTGEIIYTGYTIPGYIGVNFTFEIEKRF
                     GLSTFVENDVNCAALGELWKGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLRAGDKVAKETFEIFVE
                     NLTKGLLTITYLLNPEILILGGGILAKKDILLPEIQSSLAKNAMDNRFLPKNLVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            13545..13868
                     /locus_tag="VQ548_001694"
     CDS             13545..13868
                     /locus_tag="VQ548_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654505.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELVSIESNLEMKQQNLIDEVNKTIKENYEKIQYISSSRRGEFVEKIIGRVV
                     EKYGY"
     gene            13858..>14799
                     /locus_tag="VQ548_001695"
     CDS             13858..>14799
                     /locus_tag="VQ548_001695"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. Subunit I is part of the
                     membrane proton channel; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HET2654506.1"
                     /translation="MAISQMKRISLLFSKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFPTIQISHTSNSNHGVIEGNDALIYLMNQQQYLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNRQINRVHELERHIQSNNEEIERLIKW
                     EKLEIIPAHLEQFFFCKGKVGTIPRTVDNRLYNSFLENNIEVQEIFSNDREYGVVVFY
                     QSSCSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKNNLID
                     LQWQIDYILSIYARQISKNNLLSTPHLVALEGWIEETR"
BASE COUNT         4960 a         2255 c         2929 g         4655 t
ORIGIN      
        1 aaattatcag gaaagtacag gagcctgaat tttggaaaga agttaacttg tctgatttgg
       61 aaaaaattcg tcttgctatt cgagatttat tacagttttt ggataaaaca gaccgtaaac
      121 cctactatgt taactttgaa gatcgtatac tctccactgt tcacgagacc acagcatttt
      181 tgcaggtcaa cgatcttcgg tcttacaatg aaaaagttga gcattatttg aaaactcatc
      241 tggatgagga gtccatttct aagctatacc ataataaaaa gttgacatct gatgatatgc
      301 ttgcacttga aaaattgctt tgggaaaaat taggtagtaa agcagactac caaagtcatt
      361 atgaaaataa ggcaattccg agattggttc gtgagattat tggcttagat agagagtctg
      421 ccaatcgtat tttctctaaa tttttgtcgg atgagaatct taatgccagg cagatttcat
      481 ttgtaaaatt gattgtagac tacattgtag aaaatggttt tttagagacg aaagtgttaa
      541 cgcaagagcc gtttaaatct tatggttctg ttcaactact cttccaacac caactaccag
      601 tacttcgtaa tattgttcaa atcattgaac ttatcaataa tcgagctgga gaagcggctt
      661 aaattctaaa gtgattgcca tgctgagact catttaaaat taaaaagagt agaaatttat
      721 gctatatatg agaagtttta ttaggaagaa tgtcatcgtt ttcctagaat acagtatcag
      781 ttgttaagtg gttgataaat ttcaaagtag atacttgtac cacgatgttt gttgatcgag
      841 ttattaacaa aagagctact ttgattttaa cccaaatcat tcatacctct ctcaactaga
      901 tgtaacttac aaaacccctg acctcatgag ccactttctt cctcctcatg aggtcagttt
      961 tactttctgc tgttccagta tcgtttttcc tcgctagatt tcctcaaaag ggcagactcc
     1021 tcccttggtg cgtcacacga ttttttcatc tcgactgttc tttaatgcat cattaacgac
     1081 gcttttcttc caggtggttc ataaggaaca ggaagattca ggttgacttt tctaatccta
     1141 gaataaagtg ctgaaaacaa ttcggaatag gcatagagac tagacaattt gaggagctgc
     1201 ttgcgtcctg ttcgaacaca ttttcctacc acgtgaagaa aaagatggcg gaagcgtttg
     1261 attgttaaag tttggaagtc acctccagct agatgtttga gaaaaagata gagattgtag
     1321 gcgatacagc tcatcatcat acgaacttcg tttttgatta aggttgaact atccgtttta
     1381 tcgccaaaaa atccctcctt catctccttg atgaaattct cggcttgacc acgtccacga
     1441 taaagctgaa actggtcttg gcttgttcca ctcgtcatat ttgtaacgag agaaataaca
     1501 tcgtagaaca agtttccttc ttttcgttca gagaactggc agacacgacg cttgtgcgac
     1561 caagatcctg cttgatagag agtttctgag taggcggagt ggggcaagat ggttaagtcc
     1621 tcatcctgtg ggcaagggag ggaaaggtct ccaagacggc tcagaacagt atttttcttg
     1681 agttttatga gttagtattg ccctgttttt tcaattaaat cgtataattt gggggtcgca
     1741 aagccactat ccattcgaaa gagaagttga ttaaaccgtt ctaaaacagg tgtgataaag
     1801 ctgtctgcct cttcagaaca ataacgatta ccaggacgaa gctgggcatt gaaacaataa
     1861 cctgtcttcc cctcgaaagc ataaagagga tgatagccat gagcacgata gtgggcgtta
     1921 taagcaacac cttcttgctt gccataagtt gtgaaatggg tagaatcgat atctacaatg
     1981 agttggttta gctggtgaaa ctgtaaaaag aattcgacca attcaaggtt gaggcatcgc
     2041 aaactatgga ctgtttcctc gtcagttctg gaaagaaaac gggataaggt tggctgtgaa
     2101 gcaagctgcc ctccttccaa caattttgga aagtaggcat cagctgacaa ttctttacaa
     2161 gcatagtccg ttccatagcc tgttaacagt tgaaagagga actggacaag gatatctgaa
     2221 tccgaataac gacagtagcg gcgttggtca ttcgttacta aatacttaga aatccgctct
     2281 tttagtttca actgggaaaa aagttcctga aaaaagataa gaccaccata ctgggttaaa
     2341 tgacctccat cgaaagatag ttggtaaaaa gacttgtttt ggaagtgatg atttggtaaa
     2401 ctgttcatgt gagtttcctt tctttttgtg tttttttcta cacttatacc ataaagggga
     2461 aattcttttt tgtctagtaa aaaacaccca ttgggtgaaa aaagaaacca tacaggatct
     2521 aagctaaggc aaggattctg gatggttttt agattagggg tgaataattg gggttttaaa
     2581 gaaatagaaa acaaaaagcc gagcaagaat tcaattgcag gagaaaatga aataatactc
     2641 aatgaaaatc aaagagcaaa ctaggaaact agctgcaggc tgctcaaaac actgttttga
     2701 ggttgtagat aagactgacg aagtcagctc aaaacatggt tttgaggttg tagatgaaac
     2761 tgacgaagtc agtaaccata cctacggcaa ggcgacgttg acgcggattg aagagatttt
     2821 cgaagagtat aaatcttcct aggataaagc aaagagcctg ggacaaaata gttctcgacc
     2881 acaaaaaagc tagagatttc caattgtgga actttagctt tttaattttg agtcgttctc
     2941 ttattgtatt ttaggaggtt attggccata agtaccaatc ccatgtcaat tctcacttga
     3001 cgcttgcccc tcagattaca tctcttgtaa cccaaacaag cctttatctg cccaaagaca
     3061 ggtgacattc tttagctttc aagttttgat agccttcgtt catatacagt cccttttgag
     3121 gggctgattc aggttcgtcg gcgtagtaaa ccttgatttc ttgtttaaag tctgtctgtg
     3181 ttttctgatg tttggtatgg tgaaaacgat aataccagcc atcaggatgt gtatagctat
     3241 cctccttgtc attatagtac caattcgcta agtttctagc tgactgttta tagcctctct
     3301 tctgttcctt atcaaacatg gcatatttaa tcagatggtt tacctccttt tcatctaact
     3361 aaaggagaag caatatggct gaacgatttt gggagaactt gtccattatt ttggctgaca
     3421 gaaatatcag ctggattgag ttaaccagaa aaatgtttgc gggagagttt cactatccaa
     3481 gtgaattgaa tcgtttgtat caaaagattc gccactagaa gatggaacaa cgaatgcctc
     3541 aaagtccatg ggtagaaagg attgtgcagg tattagattt agattatgaa gatttatttc
     3601 ggaggtaatt atgaaaagaa taattccagt ttatatattc caacaagtaa atgtcctatt
     3661 ggtatctcta tacttattga aatttctttg tagcgatgag ttaactatac tacagattct
     3721 ctatggagcg tcactcattt cttttttatg gatgtatggt caacgaaaac aagtgatcaa
     3781 ggttaatatg aaaactagga tacaatggct tggtattgga ttcgttagcc tactgattat
     3841 aagtctatgt tttagtctaa tccatgcgca agaaagcacg aatcaagcaa acttaattgg
     3901 acttcaacat caaattcctt ggttttcatt tttattgttt ttaatcaatg cgagtatggt
     3961 tgaagaattt ctgtatagag aaattttatg gaacttggtt agaaaattag atattcgagt
     4021 tgctttgaca agtgttttat ttgccttagc acatcatcca ggaaccatta tagcttggtg
     4081 tttgtatgta tcgctgggga tgtttttagg gcttgtacgc tacaaattgg acttatgggg
     4141 cagtatgggg ctacatttgg tgtggaacct actagtttat agtttgctgc ttttttaaaa
     4201 taagtgatct gatttatctc ataaatcagt agtttttata ggattatttt taattcggaa
     4261 acaaaaatgt attaacagca taaaataaag aaactaggaa catttttttt attttttaga
     4321 aataaaatgt tgtatagaaa ttccgaaaga aataataaaa tcaaaataaa aattaataaa
     4381 ataggtatat ttgaacatat tgacgtcgac aaatgttctt gcaagacata aaatacaaat
     4441 aaaaagaata aaaaattttt atatttttat atttgttgtt ctgttataaa atgaaagaaa
     4501 ttagaaacta gtttctaaat catgaaaaat attgaaaaaa aaaaaataag tgttaaaata
     4561 aagaatgtaa acgtttactt caataaagga gctcatatgt tactgcaaaa agaactaatt
     4621 ccaatgatag aagctaactt accaaatatg gcatatgctg aaaaagacat tgctaaattc
     4681 ttcttaaaac agcaacctct gaataattat tcatgtaagg cattgtgcga atgccttaat
     4741 gtatccaaag caacattgac tcgatttgcg aaaaaatgtg gttttaaagg ttttagacaa
     4801 ttcattttca aataccaaga gatgattcgt gagaaagaaa agttagcatt gtatacagag
     4861 gctacagaaa aagttttatc cgactatgaa gaaatgttga gaaaaactta cacggttctt
     4921 gatgaagttc aacttgagcg tattgctgag atgatagaaa ctgctgagcg tgtatatctt
     4981 tatggtaaag taagttctgt tcttgcttta caagaaatga agatgagatt tatgcgtctc
     5041 ggagtcattg gtgaagtatt atcagacgag gatatgattt tgtggaatag cttattactt
     5101 aatgaaaatt gccttgtcat tggagcatcc gtttcaggtc aaactgatat tgtactagaa
     5161 ggtcttcaaa aagctgcgga taaaggcgct aaaacagttt taatgactac aagaaaattt
     5221 gacgaagaag attgtttctt tgatgaacta ttgttattag cttcgaccaa tcatctctcg
     5281 tatggcaatc gcatatcacc tcagtttcca atacttttaa ttacagactg cttattctct
     5341 cattatctgg aaagtccaga gagacaatat tattacaatc aaactattat ccataaggag
     5401 gaataataaa atgagtcaaa tttggactaa agaaaaattt ataagtcaag tccatggtgg
     5461 agtcattgtt tcttgtcaag ctttacccgg tgaacccctt tataatgaag aatttagctt
     5521 gatgcctttt atggctaaag cagctttaga ggcaggagca gtgggcattc gcgcaaattc
     5581 tgtgcgtgat attaaagcaa ttcagaaagt agtagattta ccaataattg gaattatcaa
     5641 aagagattat ccacctcaag aaccatatat tactgctacg atgaaagaag tagatgaact
     5701 tgtagaatgc ggaacaacag tcattgcatt tgatgcaact ttaagaccaa gatatgatgg
     5761 cttagttatc aatgaattta tcaaaaaaat aaaagaaaaa tatcctaatc aattgttgat
     5821 ggcggatgta agtaattttg atgaaggtct ctatgcattt aaatcaggcg ttgattttgt
     5881 tggtacaaca ttatcagggt acacaagtac aagtgtacaa tcagatgagc ctgattttga
     5941 actaatgaaa aaattggctg attttaatat tccggtaatt gccgaaggaa aaattcatta
     6001 tccagaacaa ttaaaaaaag cttatagttt aggtgttacc agtgttgtca ttggtggagc
     6061 gattacacgt ccaaaagaaa ttgctcagcg atttattaat gtcatcaaat aaaaaacaat
     6121 ataaaggaga aatctgatga aagatttaac taaatacaaa ggcgttattc ctgcatttta
     6181 tgcttgctat gatgaaaatg gtgaaattag ccaagaacgt gtaaaatctc tggtgcaata
     6241 tttcattgac aaaggtgtaa aaggtatcta tgtaaatggt tcttcaggtg aatgtattta
     6301 ccaaagtgta gaagatcgta aacaaattat tgaagctgtt atggaagttg ctaaaggtaa
     6361 attaacagtt atcaaccatg ttgcatgtaa taacacgaaa gatagtattg aattggcaaa
     6421 acattcagaa agtgttggag tcgatgctat tgctgctatc ccacctattt acttcaaatt
     6481 gccagaatat tcaattgcag catattggaa tgcaatgagt gaagctgcgc caaatacaga
     6541 ttttatcatt tataatattc cacaattggc aggggttgcg ttgactggta gtttgtatgc
     6601 aacaatgcgt caaaatcctc gtgtgattgg agttaaaaat tcttctatgc ctgtacaaga
     6661 tattcaaatg tttgtagctg caggtggaga agattacatt gtattcaatg gtccagatga
     6721 acaatatctt ggtggtcgct tgatgggagc agaagctggt attggtggta cttatggcgt
     6781 tatgccagat ttgttcttga aattggaaag tttgattcaa gaacgagatt tagatactgc
     6841 taaaaaactt caatatgcta tcaatgaagt tatctataag atgatatcag gtaaggcaaa
     6901 tatgtatgct gtagcaaaag aggttttgcg tctaaatgaa aaacttgatt taggttctgt
     6961 tcgtcaaccc ttagaagcat tggcagaagg tgacttggaa gttgcaaaac aagcagcaga
     7021 acttattcaa caagcacgaa aagaattttt ataataaata aaatcaatat ggagatatgt
     7081 tatgggcaca acaggattta caataattga cttaattatc ttgattgttt atttacttgc
     7141 ggtgttggtt gcaggtatct atttctctaa aaaagagatg aaaggaaaag agttcttcaa
     7201 aggagatggt tcggttcctt ggtatgttac ttcggtatcc atttttgcca caatgctcag
     7261 tccgatttcc ttcttgggac tcgctggtaa ctcttatgca ggtagctgga ttttatggtt
     7321 tgctcaatta gggatggtag tagctattcc actgacaatt cgttttatct tacctatctt
     7381 tgcacggata gacatcgata cggcatatga ttacttggat aaacgtttta attctaaagc
     7441 acttcgtatt atttcagcac tcttgtttat tatttatcaa ttgggacgta tgtctatcat
     7501 tatgtacctc ccatcagctg gtttatcagt attgacagga attgacatca atattttgat
     7561 tattttgatg ggtgcagttg caattgttta ttcttacact ggtggtctaa aatccgtatt
     7621 atggacagac tttattcaag gtgtgattct gattagtggt gtcgttttag ctttatttgt
     7681 actgatggct aatattaaag gtggctttgg tgcagtagca gaaacattag caaacgggaa
     7741 attccttgct gcaaatgaaa aacttttcga tcctaacttg ctttcaaact ccatcttttt
     7801 aattgtgatg ggttcaggct ttacaatctt gtcttcctat gcttcatctc aagatttggt
     7861 tcaacgtttt actacaacac aaaatattaa gaaacttaat aagatgttgt tcacaaacgg
     7921 tgtcttgtca cttgcaactg caacagtctt ttacttgatt ggtacaggct tgtacgtatt
     7981 ctatcaagta caaaatgcag gtagtgcagc tagcaatatc cctcaagacc aaatctttat
     8041 gtactttatt gcataccagt taccagtagg tatcacaggt ttgattttgg cagcgattta
     8101 tgcagcatct caatcaacta tttcaacagg tttgaactct gttgcaactt catggacatt
     8161 ggatattcaa gatgtcattt ctaaaaatat gtcagacgat cgtcgtacga aaattgcaca
     8221 attcgtatct ctagcagtag gtttattctc aattggtgtt tccattgtca tggctcactc
     8281 agatattaaa tctgcatacg aatggttcaa tagcttcatg ggacttgtac ttggtctact
     8341 tggtggtgta tttattcttg gatttgtttc taaaaaagca aataaacaag gtgcttatgc
     8401 agcgctgatt gtatcaacta tcgtcatggt atttattaaa tacttccttc ctccaacagc
     8461 tgtgagctac tgggcatatt cattgatttc aatctctgta tcagtagttt caggttatat
     8521 tgtatctgtt cttactggaa ataaagtatc tgcacctaaa tatacaacga ttcatgatat
     8581 tccagaaatt aaagcggatt caagttggga agttcgtcac taatagaaaa gagaaaataa
     8641 tatgattatt tctgaacaat ctgattttag acgatatgct tctatcaata aacatttttc
     8701 aaaagtctgt gattttttag aaaatacaaa tttgacagat ttagttgatg gaaaagttga
     8761 tattgacggg gaaaatgttt ttgcaaattg tatgatctat ctagctgatg gagtcccagg
     8821 agatattttt gaaactcata agaaatattt agatattcat attgttgttg aaaatactga
     8881 aaaaatggca gtaacttccc cagttcgtgc ccagtcacgt gtacctttta gcgaagaaaa
     8941 ggatattgct ttttacgata gcaaagacta tcaaattgtt gaattgcttc cagggaatat
     9001 gttggtgact tttgaagaag atcttcacca accaaagatt cattgcaatg atgagcctgt
     9061 taaaaaactt gttattaaag ttttaaacga ggaaaaataa aatgaaaaaa aatattaaac
     9121 aatacgtaac cttaggtact gcagtggtat tatcagcatt tgttgctaac tcagttgcag
     9181 ctcaggagac tgaaacttct gaagtatcaa caccagagtt ggtgcaacct gttgcaccaa
     9241 cgactccgat ttcggaagta caacctaaat cgggtaactc ttcggaagtt actgtacaac
     9301 ctagaacagt cgaaactact gttaaggatc catcttctgc aacggaagaa actcctgtct
     9361 tagaaaaaaa taatgttact ttaacagggg gcggagaaaa tgttactaat gagttaaagg
     9421 ataaatttac tagcggtgac tttactgtag tgattaagta caatcagtct agtgagaaag
     9481 gcttacaagc tctgtttgga atatctaatt ctaaacccgg tcaacaaaat agttatgtag
     9541 atgtgttcct tagagacaat ggtgaattgg gaatggaagc gcgtgatact tcttccaata
     9601 aaaatcacct agtatccaga cctgcttcag tttggggtaa gtacaaacaa gaagctgtga
     9661 ctaacactgt tgcagtagta gcagattcag tcaaaaaaac atattcttta tatgcaaatg
     9721 gtacaaaagt agtagaaaag aaagtggata acttcttaaa catcaaggat attaaaggta
     9781 ttgattacta tatgcttggg ggagtgaaac gtgcaggaaa aacggcgttt ggttttaacg
     9841 gaacactaga aaatatcaaa ttctttaata gtgcattgga tgaagaaact gttaaaaaga
     9901 tgacaacaaa cgctgttact ggacatttaa tttatacggc taatgataca acaggttcta
     9961 actatttccg tattccagtt ctgtatactt ttagcaatgg tcgggtattt tcaagcattg
    10021 acgctcgtta cggcggaact catgattttt tgaataaaat taatattgct acaagttata
    10081 gtgatgataa tggtaagaca tggactaaac caaaattaac attggcattc gatgattttg
    10141 cgccagtacc attagaatgg cctcgtgatg ttggtggacg tgacttacaa atcagcggtg
    10201 gtgcaaccta tattgactct gttattgttg aaaaaaataa caaacaagta ctcatgtttg
    10261 cggatgtgat gcctgctgga gtaagtttta gagaagctac tagaaaagat tcaggttata
    10321 aacaaattga tggtaattat taccttaaat taaagaaaca aggtgatact gattacaatt
    10381 atactattcg tgagaatggt actgtatacg acgatcgtac caacagacca actgaatttt
    10441 cagtagataa aaatttcggt attaaacaaa atggtaatta tttgacagta gagcaatatt
    10501 cggtttcatt taaaaataat aaaaagactg aatatcgtaa tgggactcac gtccatatga
    10561 atatcttcta caaagatgca ttgttcaaag tagtgccaac gaactatatt gcatatattt
    10621 ctagcaatga tcatggcgaa tcttggtctg caccaacttt attacctcct ataatgggac
    10681 ttaatcggaa tgcgccttat ttgggtcctg gacgtggaat cattgaaagc tcaactggac
    10741 gtattcttat tccgtcttac actggtaaag agtctgcatt catttatagt gacgataatg
    10801 gagcatcttg gaaagttaaa gttgtgccac ttccttctag ttggtcagca gaagcacaat
    10861 ttgtagaatt gagtccagga gtaattcaag catacatgcg tacaaataat ggtaaaattg
    10921 catatttaac aagtacagac gcaggtacta cttggagtgc accggaatat ttgaaatttg
    10981 tttcaaatcc aagttatgga acacaattat caatcatcaa ttatagtcaa ctgattgatg
    11041 gtaaaaaggc tgtcatttta agtactccaa actccacaaa tggtcgtaaa cacggacaaa
    11101 tttggattgg tctaattaat gatgataata caattgattg gcgttatcat cacgacgttg
    11161 attatagtaa ctatggatac tcatattcaa cattgacaga gttaccaaat catgaaattg
    11221 gattgatgtt tgaaaaattt gattcatggt ctcgtaatga acttcatatg aaaaatgttg
    11281 taccatatat aacatttaag attgaagatc tgaaaaagaa ttaaagctga aatttgaaaa
    11341 tatataaaaa gaggataaaa attatggtaa attacggtat tgttggagct ggatattttg
    11401 gagctgattt agctcgctca atgaacaaaa ttgaagatgc aaaagtggtt gcggtatttg
    11461 acccaaatca tggagaagaa gttgctcaag agttgggatc agatgtttgt gcaagtttag
    11521 atgaacttgt agcacgtgaa gatattgatt gtgtgatcgt agcttcacct agctaccttc
    11581 accgtgaacc agttgtgaaa gctgctcaac atggcaaaca cgtattttgt gaaaagccaa
    11641 ttgcattgtc ttatgaagat tgtaaagcca tggttgacgc atgtaaagaa aataatgtta
    11701 tctttatggc tggtcacatc atgaacttct ttaacggtgt acaccatgct aaagaattga
    11761 ttactcaagg taaaatcggt aaagttcttt attgccatgc cgctcgtaca ggttgggaag
    11821 aacaacaacc aactgtatca tggaagaaac ttcgttctca atctggagga catttgtacc
    11881 atcatattca tgaattagat tgcattcagt ttatcatggg aggacttcct gaaaaagcga
    11941 caatggtagg aggcaatgta tatcataaag gtgaaaactt tggtgatgaa gatgatatgc
    12001 tcattgtaaa cttagaatac tctgatgatc gttatgctgt tttggaatat ggtaatgctt
    12061 tccgttgggg tgaacactac gtcttgattc aaggaactga aggagctatc aaacttgatt
    12121 tgttcaatac tggaggtact cttcgtgtta aaggtgaagg agaatcacac ttcttagttc
    12181 atgaaactca agaggaagat gatgaccgta cagctatcta taccggtcgt ggtatggatg
    12241 gagcaattgc gtacggtaaa ccaggagtac gttgcccatt atggttgcaa acatgtattg
    12301 ataaagaaat ggaatatcta catgacatca ttaaaggtgg agaaattaca gaagaatatg
    12361 aaaaacttct caatggtgta gctgctttag aatcaatcgc taccgctgat gcatgtactt
    12421 tatcagttaa agaagatcga aaagtaagtc tttcagaaat cacaaatgct taacttttgt
    12481 aaaacagaat agtaaattct tatcattata taatttctaa agttctgtga tacaactcat
    12541 tgaataaaga aatagagatg ggactgggat aatgcccagt cccatttttt atcaaaaagt
    12601 aatgagatca aaaatgtggg agtgatgaaa tgaagattat agggatcgat attggcggaa
    12661 caacaattaa agcagattta tacaatgagt ttggaacgag tttaaatcag ttcaaagaga
    12721 tagaaacaat tattgactat gatttgggaa cgaaccagat attaaatcag gtctgtgatt
    12781 taattggtga gtatatttta aatcattcaa ttgatggtgt tgggatttcc actgctggag
    12841 ttgttaatgc taatacagga gagatcatct atacaggcta tacaatacca gggtatatcg
    12901 gagtaaactt tactttcgaa atagaaaaac gttttgggtt gtctactttt gttgaaaatg
    12961 atgttaattg tgctgcatta ggtgaattgt ggaagggaca agccaaagat aagaaaaatg
    13021 tagtaatggt tactattgga acaggtatag gaggcagtat tattgtcaat ggacaaattg
    13081 ttaacggatt taactatact gctggtgaag taggctatat tcctgtaggt aattcggatt
    13141 ggcaaagcaa agcctcaaca accgcattga ttcatttata tcaaaagaaa agcttgaaaa
    13201 ctaatcaaac tgggcgtact ttctttactg atttaagagc tggagataaa gtcgctaaag
    13261 aaacttttga aatttttgta gaaaatctaa caaaaggttt attaacgatt acttatctac
    13321 ttaatccaga aattctcata ttaggaggtg ggatcctggc taaaaaggat attttgttac
    13381 ctgaaattca aagttcttta gctaaaaatg caatggataa taggtttttg cctaaaaatc
    13441 ttgtggcagc tacattagga aatgaagctg gtcgtatagg agctgtaaaa aatttcttag
    13501 atagaatttc taataaatag tatgaaagat aaggaggtgt cacaatgact aactctgtat
    13561 tttcgacaat gcaagatatt gagaatgttg caaccgatat tataaaatca tatgataatg
    13621 agatttatac ttataaagct gtttcccaag aagaattgga aaaactagaa aaaagttatg
    13681 atgaaaaaag tcacgaagaa ttagtttcaa tagaaagcaa tttagaaatg aaacaacaga
    13741 accttattga tgaggttaat aaaacaatca aggaaaatta tgaaaagatt cagtatattt
    13801 catcaagtag gagaggagaa tttgtagaaa aaattattgg tagggtggta gaaaaatatg
    13861 gctattagtc agatgaaaag aatttctcta ctattttcta aaagtagtct tgatgatgtt
    13921 ttaaaaacta ttcaagaact agagtcagtg cagttccgtg atttaaaggt tcaggataac
    13981 tggtcagaag ctctagaaaa agatgaggtt gtatttccaa ctattcaaat ttctcatact
    14041 tctaattcca atcatggggt tattgaagga aatgatgcct tgatttattt gatgaatcaa
    14101 caacaatatt tagaagcaac tgtagagaaa ttacaagaat acctaccgaa agaaaacacg
    14161 tttaaattat tacagcaacc tccgataacg acctcttatg aagaattaga aaaatttggt
    14221 aaagctaatg ttgctgaggg tgttcttaaa aaagtgaatc gtcaaataaa cagagttcat
    14281 gaattagaaa gacacattca aagtaataat gaggaaatag agagattaat aaaatgggaa
    14341 aaattagaaa ttattcctgc gcatttagaa caattttttt tctgtaaagg aaaagtcgga
    14401 acaattccaa ggactgtaga taatcgctta tacaatagtt ttttagaaaa caatattgaa
    14461 gttcaagaaa tattttctaa tgatagagag tacggtgttg ttgttttcta tcagtccagt
    14521 tgctctattg attttgatga atacttattt gaaccatttg attattctag aaaggaatta
    14581 ccgaagcagc gagtagtaga tttggatcaa gaaaacatgc agttaataac tgaaaaagag
    14641 aatattatcg catcgttgca agattcaaag aataatttga tagatttaca atggcaaatt
    14701 gactatattt tatctatcta tgctcgtcaa atctctaaga ataacctttt gagcactccg
    14761 catctagttg cactagaagg atggatagaa gaaactcgt
//
LOCUS       DAVBEM010000050        14476 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVBEM010000050 DAVBEM010000000
VERSION     DAVBEM010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14476
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.050"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            3..350
                     /locus_tag="VQ548_001696"
     CDS             3..350
                     /locus_tag="VQ548_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654507.1"
                     /translation="MLRLPYKKQKISHFTVSEDKDICRYIRQQLYYQNLFWMKEQAEA
                     YQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPP
                     AFYQQYFLKNMVE"
     gene            369..2171
                     /gene="pepF"
                     /locus_tag="VQ548_001697"
     CDS             369..2171
                     /gene="pepF"
                     /locus_tag="VQ548_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET2654508.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEVLKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTFYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGIYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            2173..2886
                     /locus_tag="VQ548_001698"
     CDS             2173..2886
                     /locus_tag="VQ548_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HET2654509.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELENFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            2953..3894
                     /gene="prsA"
                     /locus_tag="VQ548_001699"
     CDS             2953..3894
                     /gene="prsA"
                     /locus_tag="VQ548_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HET2654510.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(4011..4352)
                     /locus_tag="VQ548_001700"
                     /pseudo
     CDS             complement(4011..4352)
                     /locus_tag="VQ548_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            4765..4860
                     /locus_tag="VQ548_001701"
                     /pseudo
     CDS             4765..4860
                     /locus_tag="VQ548_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5113..5733)
                     /locus_tag="VQ548_001702"
     CDS             complement(5113..5733)
                     /locus_tag="VQ548_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2654511.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(5733..6215)
                     /locus_tag="VQ548_001703"
     CDS             complement(5733..6215)
                     /locus_tag="VQ548_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HET2654512.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(6215..7057)
                     /locus_tag="VQ548_001704"
     CDS             complement(6215..7057)
                     /locus_tag="VQ548_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HET2654513.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(7152..7952)
                     /locus_tag="VQ548_001705"
     CDS             complement(7152..7952)
                     /locus_tag="VQ548_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HET2654514.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            8096..9475
                     /gene="glmU"
                     /locus_tag="VQ548_001706"
     CDS             8096..9475
                     /gene="glmU"
                     /locus_tag="VQ548_001706"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HET2654515.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            9485..10030
                     /locus_tag="VQ548_001707"
     CDS             9485..10030
                     /locus_tag="VQ548_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2654516.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTARRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            10042..10356
                     /locus_tag="VQ548_001708"
     CDS             10042..10356
                     /locus_tag="VQ548_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HET2654517.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            10373..11065
                     /locus_tag="VQ548_001709"
     CDS             10373..11065
                     /locus_tag="VQ548_001709"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HET2654518.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            11142..11633
                     /gene="rocS"
                     /locus_tag="VQ548_001710"
     CDS             11142..11633
                     /gene="rocS"
                     /locus_tag="VQ548_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HET2654519.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            11731..12321
                     /locus_tag="VQ548_001711"
     CDS             11731..12321
                     /locus_tag="VQ548_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HET2654520.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            12330..14093
                     /locus_tag="VQ548_001712"
     CDS             12330..14093
                     /locus_tag="VQ548_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HET2654521.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            14307..>14476
                     /locus_tag="VQ548_001713"
     CDS             14307..>14476
                     /locus_tag="VQ548_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2654522.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASYVFQISRNTIYGWLKLKEK
                     TGELNHQVKGTKP"
BASE COUNT         4578 a         2587 c         3005 g         4306 t
ORIGIN      
        1 aaatattgcg tcttccctat aagaaacaaa aaatatctca ttttacagtt tctgaggaca
       61 aggacatctg tcgctatatc cggcaacaac tttattatca aaatctcttt tggatgaaag
      121 aacaagcaga agcctatcaa aagggagaaa atatcctgac ttatggactg aaagaatggt
      181 atccacaaat tcgaccaata gtgggcaaat ttttccagat tgaacaagac ttgactagct
      241 attatcagca cttttatacc tattaccaaa aaaatcctca aaatgattgg caaaagcttt
      301 atccaccagc cttttatcag caatatttct tgaaaaatat ggtagaatag aaaggatgga
      361 ggaatctaat ggtattacaa agaaatgaaa taaatgaaaa agatacatgg gatctatcaa
      421 cgatctaccc aactgaccag gcttgggaag aagtcttaaa agatttaaca gaacaattgg
      481 agacagtagc ccagtatgaa ggccatctct tggatagtgc ggataaccta ctagaaatca
      541 ctgaattttc tcttgaaatg gaacgccaga tggagaagct ttacgtttat gctcatatga
      601 agaatgacca ggatacacgt gaagctaagt atcaagagta ctatgccaag gccatgacat
      661 tctacagcca gttagaccaa gccttttcat tctatgagcc tgaatttatg gagattagcg
      721 aaaagcagta tgctgacttt ttagaagctc aaccaaagct gcaggtttat caacactatt
      781 ttgacaagct cttgcaaggc aaggatcacg ttctctcaca acgtgaagaa gaattattgg
      841 ctggagctgg agaaatcttt ggttcagcaa gtgaaacctt cgctatcttg gacaatgcgg
      901 atattgtgtt cccttatgtc ctagacgatg atggtaaaga agttcagcta tctcatggga
      961 tttacacacg tttgatggag tctaaaaaac gtgaggttcg ccgtggtgcc tatcaagctc
     1021 tttatgcgac ttacgaacaa ttccaacaca cctatgccaa aaccttgcaa accaatgtta
     1081 aggtgcaaaa ttaccgtgct aaagttcgta actacaagag tgctcgtcat gcagccctcg
     1141 cagcgaattt tgttccagaa agtgtttatg acaatttggt agcagcagtt cgcaagcatt
     1201 tgccactctt acatcgctat cttgagcttc gttcaaaaat cttggggatt tcagatctca
     1261 agatgtacga tgtctacaca ccgctttcat ctgttgaata cagttttacc taccaagaag
     1321 ccttgaaaaa agcagaagat gctttggcag tcttgggtga ggattacttg agccgtgtta
     1381 aacgtgcctt cagcgagcgt tggattgatg tttacgaaaa tcaaggcaag cgttcaggtg
     1441 cctactctgg tggttcttac gataccaatg cctttatgct tctcaactgg caggacaatc
     1501 tggacaatct ctttactctt gttcatgaaa caggtcacag tatgcattca agctatactc
     1561 gtgaaactca gccttatgtt tacggagatt actctatctt tttggctgag attgcctcaa
     1621 ctaccaatga aaatatcttg acggagaaat tattggaaga agtggaagac gacgcaacac
     1681 gctttgctat tctcaataac ttcctagatg gtttccgtgg aacagttttc cgccaaactc
     1741 aatttgctga gtttgaacac gccattcacc aagcagatca aaatggggag gtcttgacaa
     1801 gcgatttcct aaataaactc tacgcagact tgaaccaaga gtattatggt ttgagtaagg
     1861 aagacaatcc tgaaatccaa tacgagtggg ctcgcattcc acacttctac tataactact
     1921 atgtatatca atattcaact ggctttgcgg ccgcctcagc cttggctgaa aaaattgtcc
     1981 atggtagtca agaagaccgt gaccgctata tcgactacct caaggcaggt aagtcggact
     2041 atccacttaa tgtcatgaga aaagctggtg ttgatatgga gaaggaagac tacctcaacg
     2101 atgcctttgc agtctttgaa cgccgtttaa atgagtttga agcccttgtt gaaaaattag
     2161 gattggcata aaatggttga atcgtatagt aagaatgcta accataacat gcgtcgtcct
     2221 gtcgtcaaag aagaaattgt agacttgatg cgtcagcgtc aaaagcaggt cacaggtttc
     2281 ttgaaagaat tggaaaactt tgcccgcaag gaaaatattc ctattattcc ccatgaaacg
     2341 gttgcttatt tccgttttct tatggaaacc atgcagccta aaaatattct ggaaattggg
     2401 acggctatcg gtttttcagc tctcttgatg gctgaacatg cgccaaatgc taagattaca
     2461 actattgatc gtaatccaga aatgattggt tttgccaagg aaaattttgc ccagtttgac
     2521 agtcgcaagc aaatcactct cctagaggga gatgcggtgg atgtcttatc tacactgaca
     2581 gagtcttatg atttcgtctt tatggattct gccaagtcta aatacatcgt ctttctgcca
     2641 gaaatcctca aacatttgga agttggtggt gtggttgtct tggatgatat ttttcaaggt
     2701 ggtgatgttg ccaaggatat tatggaagtc cgtcgtggtc agcgaaccat ttatcgaggc
     2761 cttcaaaaat tatttgatgc aaccttagac aatccagaac tcaccgcaac attagtgcct
     2821 ttaggagatg gtattctcat gcttcgtaaa aatgtagcag atgttcaact gtctgaaagc
     2881 gaatgatttt cagaaaaatt taagaaaaaa tagtaaaata gatagagtaa cacttatctc
     2941 aaaggagtag acatgaagaa aaaattattg gcaggtgcca tcacactatt atcagtagca
     3001 actttagcag cttgttcgaa agggtcagaa ggggcagacc ttatcagcat gaaaggggat
     3061 gtcatcacag aacatcaatt ttatgagcaa gtgaaaaaca acccttcagc ccaacaagtc
     3121 ttgttaaata tgaccatcca aaaagttttt gaaaaacaat atggctcaga gcttgatgat
     3181 aaagaggttg atgatactat tgccgaagaa aaaaaacaat atggcgaaaa ctaccaacgt
     3241 gtcttgtcac aagcaggtat gactcttgaa acacgtaaag ctcaaattcg tacaagtaaa
     3301 ttagttgagt tggcagttaa gaaggtagca gaagctgaat tgacagatga agcctataag
     3361 aaagcctttg atgagtacac tccagatgta acggctcaaa tcatccgtct taataatgaa
     3421 gataaggcca aagaagttct cgaaaaagcc aaggcagaag gtgctgattt tgctcaatta
     3481 gccaaagata attcaactga tgaaaaaaca aaagaaaatg gtggagaaat tacctttgat
     3541 tctgcttcaa cagaagtacc tgagcaagtc aaaaaagccg ctttcgcttt agatgtggat
     3601 ggtgtttctg atgtgattac agcaactggc acacaagcct acagtagcca atattacatt
     3661 gtaaaactca ctaagaaaac agaaaaatca tctaatattg atgactacaa agaaaaatta
     3721 aaaactgtta tcttgactca aaaacaaaat gattcaacat ttgttcaaag cattatcgga
     3781 aaagaattgc aagcagccaa tatcaaggtt aaggaccaag ccttccaaaa tatctttacc
     3841 caatatatcg gtggtggaga ttcaagctca agcagtagta catcaaacga atagtccaaa
     3901 tcaatgagtc agggaaaaaa actcgacttc aggaaaaaat gaagcaaaca ttcccacaat
     3961 aaaacgcata gtacaaggtt tgtactgacc ccaaaagtta gacaattaat ttatctgaag
     4021 gatttagttc tgtattgcac agggctaagt ccttttagtt ttaccttaat tctcttattg
     4081 ttgtaataat caatatagtc tataatggct tgttccaatt gattaagtga tttaaatgtt
     4141 ttctcatagc cataaaacat ttcggatttt aaaatgccaa agaaagattc catcctaccg
     4201 ttgtcttggc tgtttccttt gcgtgacata gatgcttgaa ttcccttact ctctaggaag
     4261 cgatgataag aatcgtgttg gtattgccag ccttggtcac tatggagaat cgtattctcg
     4321 tagtgcttct ctttgaatgc ctgttccaac attaacgatc aatcaattta atcatgtacc
     4381 taatattaga attgtttatc ccaaatttat ttgaaagctt ctctaagcta tatccttgtt
     4441 ttctaagttc atagatctga actttatcat cataagttaa tttcataata aaaacacccc
     4501 aaaagttaga ttttttctgt ctaacttttg gggtgtagtt catgtacacc tgatatgatg
     4561 cgttttataa ttttaaagac tttttgacca gcctcatttt tttaacttga tactcagtga
     4621 aaagcaaaga ttaaactagg aagctagctg taggctgctc aaagaacagc tttgaggttg
     4681 cagataaaac ttgtgaggtc accaacatat ataatgtgaa gctgacgtga cttgaataga
     4741 ttttagaagg gtatgagtct ggaagtttta atggataatg caagattcca tagaatgggt
     4801 aagctagagt tcttatgtga agagtttggg cataaacttt taccttttcc tccctactca
     4861 tcttagtata gaaaagtgaa tctaaaatag tacataactg cttctaaaac attcttataa
     4921 attgatttaa attctcaaat catattattc agttcttatt tcattttgct ctacaatcct
     4981 gttgagaaga cacgtgttca tatcaaaaag gtattggcaa gttgcaatac ctttttacaa
     5041 ggttcttttg tcttattttt gtttcaactg actatatctc ctatggttct agttcagaag
     5101 gctaggctat aattatgatt gataagaagt atcattccaa gtattgagag tgaatgtttc
     5161 aaaatcatgg gtttctataa tggtcaggct ggcatttgct agaccgccat ctttacgaag
     5221 aagtggttct ttatagccta ggagagtacg aagactggca gtaagattgg cgccgtgtcc
     5281 gacaattaga atacgctcag ctggactatc ttttaatgat ttgataaatt ggatggtccg
     5341 ttgagttgta ctatagaggg attcggctcc gaacattcga gtgtcaaatt gagcaagatt
     5401 tgaacgaaaa gcctggattt gttgcgggta aatagcttcc aaggttgcaa ttttcaaacc
     5461 ttctaacttc ccaagttgcc attcacggag attaggaacg atttctaaag aacagggggt
     5521 atagagttga ctttggataa tctcagcaga tttgaccgct cgaggtaaat cacttgaata
     5581 aatctgatca aaaggaattt ccttgagata ctggccaagt cgttttaggg tttcaatgga
     5641 ttcaggaaga agaggagaat caccgctagc accttgaaaa cgaccttctt ggttccagag
     5701 ggtacgaccg tggcggacaa agtagagttt cattacttga tgtcctccaa aatatctaca
     5761 aagtctgcct ttacaaagct agccaagtct tgtggcgcga cgataatgct gtgtccgact
     5821 tcgcctgcag agacaatcat tcgatccaaa tctagagcaa ttttatcgat aaaaatggga
     5881 taattgtgtt tctgacgaat tccgacagga ttattggctc catgaatgta accagttgtt
     5941 ttttctaagt ccttttgtgg aatcatgctc acttttttat tgccagaaat tttagctagt
     6001 ttcttttcag acaagtgctg agtgataggg acaattccga taatcggtcc ggtcttgtct
     6061 cccaaaagcg ccaaggtttt gaaaatctga tctcgttcat aaccttgagg aagctctcct
     6121 tctagggcat tgatttgaat cccctgatga gggatagctg ctttagatag gatttgttcc
     6181 accaatgttt ttttgatttt aacttttttt gccattattt atatttatcc tccaattgac
     6241 tcatccaaat accaagccag attcccagcg caaagaagaa ggcgatgatg acataaccga
     6301 caagtgaaag tcctgtgtat tggatacttt cagcgtttcc tgcatttgga attaagatca
     6361 aaagggtact tgataggacg ataccgatga tgaaatgata gacgcgtgag tggtagttgt
     6421 ttaaggcata atccatcaat tttgaaaaaa cgatgagagt tgcacctgca ccaattccaa
     6481 tcggaaagaa ggttcccaag agatcaaaag ttttaaaacc agtcaacata ggagcataga
     6541 gtcccaaaat caaaagtaag ttcgatgggc tgaggccagg aaccaagacg ccaagggcca
     6601 atagtgcgcc tgctaggacg aagttaagaa agctggcgct taaggttcca acgacaaaat
     6661 ttaaggcata gagtcctaat ccagaaatga taaaggttgt ccataaccaa gctaaatcaa
     6721 tcttgtctcg gtcagattct cgagttgatt ctttgaggag gctaggaact gtaccgataa
     6781 tagctcccgc aaagctccat aatacaaaga cctgataatt ttcaagcagg tattcaatcg
     6841 ggtaggaaaa taagccgatt cccagaagca taccgatggc aactggaata aagtacaaaa
     6901 cattttcttt aaggtcttta aagggatggg ccagaaagcc aatcattcgt tcatagattc
     6961 ctaagattgc tgctagaacc cctccggaaa ttcccggtag gataaatcca agagcaatta
     7021 caatcccttt aataacgcgt gctaaccatg agagcatata tttcctccaa ctatttctat
     7081 ttcaaaaatt ccttactata ttgtatcaca atcagacaca aaaagaaaaa gcaaatgata
     7141 aacaaatgct tttaaggttt taaaaaaagt tttcgaaagg tttcttcttt attttttaag
     7201 ggagagataa cgttgatatc taaatcgtgg tcaaagccgg caatttttcc tttagatgtg
     7261 tattggtgaa tatcataatc taaatcagtt ttaggactgc tctccaaaaa tcctgagtct
     7321 gagccgtagg acggaatcca aacagaggta aacttgcctg tatcaatact gtgttcttcc
     7381 atgaagtaga caccaacgta gatgccgatg tttttagcac ctagtgatgc tagttttgct
     7441 cgaaagtttt cgacaccttc gttcatatta gacatggttt tgtcttccac gtcaagccaa
     7501 tagtaactag ggctgtaagg agaggcagca ttgtagaaaa cttcggcagc cttttccatt
     7561 tcttggacac tttttccagc tacataagcg tagacagcaa ctgggacatt ccgcttttga
     7621 agttcagtga tatgactctt ataggccttg tctattccat tgataaatga agcatcattt
     7681 tcttttgttg tttgagcacc actgtgaaca cgaacaatag cacctgaaat attttgtgag
     7741 agggcatcgt agttgatttc ctcaggacgc tgccagccag agaggtcaat aatcggtttg
     7801 tctaagtgtt tcaaagcctg tgcttcaatc tgtgctatat tggattttgt tttaaacgat
     7861 tggctgtcat taagtgggcg attgatgatt aaaatgaaca tcataatccc aaaaaaacta
     7921 aataaaataa gtggatgaat ttgttttctc atatcttata agtctaccct aaaaatcaaa
     7981 aaaaatcaaa aaaatgggtt aaggaagaga ctttagagca ttttttcatt caagagtgcg
     8041 gaatgatttg aaatatggta taataaaagg gaatttctac agaaaagaga agattatgtc
     8101 aaattttgcc attattttag cagcgggtaa agggactcgc atgaaatctg atttgccaaa
     8161 agttttgcac aaggttgcgg gtatttctat gttggaacat gttttccgta gtgtgggagc
     8221 tatccaacct gaaaagacag taacagttgt aggacacaag gcagaattgg ttgaggaggt
     8281 cttggctgga cagacagaat ttgtgactca atctgaacag ttgggaactg gtcatgcagt
     8341 tatgatgaca gaacctatct tagaaggttt gtcaggacac accttggtca ttgcaggaga
     8401 tactccttta atcactggtg aaagcttgaa aaacttgatt gatttccata tcaatcataa
     8461 aaatgtggcc actatcttga ctgctgaaac ggataatcct tttggctatg gacgaattgt
     8521 tcgtaatgac aatgctgagg ttcttcgtat tgttgagcag aaggatgcta cagattttga
     8581 aaagcaaatc aaggaaatca acactggaac atacgtcttt gacaacgagc gtttgtttga
     8641 ggctttgaaa aatatcaata ccaataacgc tcaaggcgaa tactatatta cagacgtcat
     8701 tggtattttc cgtgaaactg gtgaaaaagt tggcgcttat actttgaaag attttgatga
     8761 aagtcttggg gtaaatgacc gtgtggcgct tgcgacagct gagtcagtta tgcgtcgtcg
     8821 catcaatcat aaacacatgg tcaacggtgt tagctttgtc aatccagaag caacttatat
     8881 cgatattgat gttgagattg ctccggaagt tcaaatcgaa gccaatgtta ccttgaaagg
     8941 gcaaacgaaa attggtgctg agactgtttt gacaaacggt acttatgtag tggacagcac
     9001 tatcggagca ggagcggtca ttaccaattc tatgattgag gaaagtagtg ttgcagacgg
     9061 tgtgacagtc ggtccttatg ctcacattcg tccaaattca agtctgggtg cccaagttca
     9121 tattggtaac tttgttgagg tgaaaggatc ttcaatcggt gagaatacca aggctggtca
     9181 tttgacttat atcggaaact gtgaagtggg aagcaacgtt aatttcggtg ctggaactat
     9241 tacagtcaac tatgacggca aaaacaaata caagacagtc attggagaca atgtctttgt
     9301 tggttcaaat tcaaccatta ttgcaccagt agaacttggt gacaattccc tcgttggtgc
     9361 tggttcaact attactaaag acgtgccagc agatgctatt gctattggtc gcggtcgtca
     9421 gatcaataaa gacgaatatg caacacgtct tcctcatcat cctaagaacc agtaggagcc
     9481 tatcatggag tttgaagaaa aaacgcttag ccgaaaagaa atctatcaag gaccaatatt
     9541 taaactggtc caagatcagg ttgaattacc agaaggcaag ggaactgccc gacgggattt
     9601 gattttccac aatggggctg tctgtgtttt agcagtaacg gatgaacaaa aacttatctt
     9661 ggtcaagcag taccgcaaag ctatcgaggc tgtctcttac gaaattccag ccggaaaatt
     9721 ggaagtagga gaaaacacag cccctgtggc agctgccctt cgtgaattag aggaagaaac
     9781 agcctataca gggaaattag aactcttgta cgatttttat tcagctattg gcttttgtaa
     9841 tgagaagtta aaactatatt tagcaagcga tttgacaaaa gtggaaaatc cgcgtccgca
     9901 ggatgaggat gaaaccttgg aagtccttga agtgagctta gaagaagcga aagaattaat
     9961 ccaatcaggt catatctgtg atgccaagac aattatggct gttcagtatt gggagttgca
    10021 gaaaaaatag aggaggtcag tatgggtaaa tctttattaa cggatgaaat gattgaaaga
    10081 gctaatagag gcgaaaaaat ttcaggtcct cctttgctag atgataatga ggaaactaag
    10141 attttaccaa cctcttcttc ccgttttggt tatgccaatc ctaaggatca tggttttagc
    10201 caggaaacct tgaagattca ggtcgaacca tctattcata aaagccgtcg tattgaaaat
    10261 accaagagaa atgtcttcaa ttctaagttg aataaaatct tatttgcggt catctttctc
    10321 ttgattttgc ttgttttagc aatgaaactt ttgtaataga aaaggaattg aaatgaaaat
    10381 aggaattatt gctgctatgc cagaagaact ggcttatctg gtccagcatt tagataatac
    10441 ccaggagcaa gttgttttgg ggaataccta tcatacagga accattgctt ctcatgaagt
    10501 cgttcttgta gaaagtggaa ttggtaaggt catgtctgct atgagtgtgg cgattttggc
    10561 tgatcatttc caggtggatg cccttattaa tacgggttca gctggggcag tagcagaagg
    10621 tatcgctgtt ggggatgtcg tgattgctga caaattagcc tatcatgacg tggatgtcac
    10681 agcttttggc tatgcttatg gacaaatggc gcaacaaccg ctttatttcg aatcagacaa
    10741 aacctttgtt gctcaaatcc aagagagttt atctcaattg gaccaaaact ggcatcttgg
    10801 tttgattgct acaggagata gttttgttgc aggaaatgac aagatagaag cgattaagtc
    10861 ccatttccca gaagttttag ccgtggagat ggagggggca gctattgctc aagcagcgca
    10921 tgccctcaat ctcccagtct tagtcatcag agctatgagt gacaatgcca accatgaagc
    10981 aaacatcttt tttgatgagt ttattatcga agctggacgt cgctctgccc aagtcttgtt
    11041 gacctttttg aaggctttag attaagcgga aatttgacag tttttctagc ttatgataag
    11101 atttaagtaa agaaaagcta gaaaacgttt cagaggatat tatgagtatt gaaatgaccg
    11161 tcagtgagat tgcagaggtc ttaggattat ctcgccaagc aatcaataac cgtgtcaaag
    11221 aattaccaga agaagacaca gataaaaatg acaaaggggt aacagttgtt accagaagtg
    11281 gcttgattaa gctagaagaa atctataaaa aaacgatttt tgaagatgag cctgtcagtg
    11341 aagatgtcaa acaacgtgaa ctgatggaga ttctagtgga tgagaagaat gcagaaattc
    11401 ttcgtcttta tgaacaatta aaagccaagg atcgtcagtt atcagaaaaa gacgagcaga
    11461 tgcgtatcaa agaccgtcag attgctgaga aagacaaaca attagatcag caacaacaat
    11521 tgacccttca agccatgaag gatcaagaaa atcttaagct agagctggac caagcaaaag
    11581 aagaagtcca atccactaag aaaggctttt ttgctcgttt atttggagga taatcaagga
    11641 gctgtttagg ttaaatgcta acctgatggc ttcttttgtt tgtgaatagt atagttgatt
    11701 agaacagaga cagtagagga gaggtacaga atggaacgat tagaagatta cattgctttt
    11761 gacttagaat ttaatcagca cgaaggacaa acacacttga ttcaagtatc ggcagtgcgt
    11821 tttagagatg gtcgggaaat cgatgcctat gattcctatg ttcataccag cgtccctcta
    11881 aaaagcttta tcaatggttt gaccgggatt acagctgaga ccttaaaaga tgctcctcca
    11941 gttgagaaag tcttagaaga attccaagag tttgtgggtt ctttgctgat gataggctac
    12001 aatgctgcta aaagtgattt acctatttta gcagagcatg gtttagacta tagccaacag
    12061 tacaaggtgg atttgtatga tgaagctttt gaacgtcgga gttcagattt acatggtatt
    12121 gccaatctca aattgcaaac tgttgcctca tttcttggat ttcaaggtca gtctcataat
    12181 agtttagagg atgctcggat gacggcgcgt gtttacgaat ccttcttaga gtcggatcaa
    12241 gctagggaat tgttagagac agaaagtagc ttatcaaaca atccttttgg tgtcttggac
    12301 ttgtctcaat tatttgacta ggagtgccta tgaaacctga aaaacctaaa aaattgggtc
    12361 ttaaacagat ttacctcaat cttgataaaa tcctctttct atttttcttg atttttatga
    12421 tagtggagta tttgtgggta ccattcaatt catggttggc tagcttctta ttagatcaga
    12481 caggttatct ttttatttcc tataacaatg tcttagccat ccttactcat tctccattga
    12541 ttagtctagc ttttttagcc ttgattgtaa ttaaccttct ggttgcttat tttcaaatag
    12601 gactcctctt tattggtgct cgtcatctcc tctataatga aaagcgaagg ctaattgagt
    12661 atatccgcaa ggttttccat gaaagttttg gatttatgaa aaagctaact tgcgctaaag
    12721 ccttgtttat ctttttctat atagctatgc tttttccttt tatacggaaa atgctgaaga
    12781 tttattatct taataaaatc gtcattccag agtttatcca agcttattta gaagataaat
    12841 attggatgtg gtggctgagc atcctacttc tatctcttat ctttctctat gtctctgtca
    12901 gattgatgtt tgcccttccg aagattgtat atgatcagct gactgttcga gaagcagtga
    12961 tgtttagctt ggagaaaacc aagaagagag ttacttttta tgcttggaat ttattttaca
    13021 tcttgctcaa agcacattta ttattttatc ttcctttgat tcctttatta ttggctcaaa
    13081 ctttggtaga tgatatcact cagagagagt ctctgattct tggtattttg aattttgtcg
    13141 tgattaaaaa tctctattat atggctctga cttatttttt ggttaaattt gtttcatttt
    13201 tgacaggaaa ggagctggat atgcttccta ggagagaaaa agatcacatc gtgcgatggg
    13261 gtgtcatgac ttgtgccagt cttttctttg ccttagaagg ttatatttat ctggaggctc
    13321 ccatggttca tctacctcaa cttatttctc accgaggggt ttccaatgca aatgggattc
    13381 aaaatacagt agagtccttg gaaactacag cacaactcaa accagacttg gtggagacgg
    13441 acgtgcagga aacaaaagat gggcagtttg tcatgatgca tgatgctaac ttgaaaaatc
    13501 tagcaggtat caataaaagt cctcaagact taaacttgga ggagcttaaa gggattgata
    13561 tttttgaaaa tggctaccag actaaaattt caagctttga agattatctc agtcgagcca
    13621 acgaacttgg tcaaaaatta ctaattgaaa ttaaaaccag taaaaaagat agtccagaca
    13681 tgatgaaccg ctttttagcc cgttatgctg caaagctcaa gatttatgga catcaaatcc
    13741 agtctttaga ctaccatgtt gtcgaaaaag taagacagta tgatgccgaa ctgccagttt
    13801 atttcatcat gccctacaat tctgtctttc ctaaaacaag agcgacagga tatactatgg
    13861 agtactcaac cttggatgaa tattttgtaa gcaaactatg gacaacggat cagaaacttt
    13921 atgtctggac tgtcaatgat tcagaagcta tcagcaaatc tcttcactta ggagtagatg
    13981 gagtgattac agatgatttg gaaaaagttc agcgggaaat agaagtagcc caagaagatc
    14041 cagaatatac ggatttgctc ttgaaaaaag cattggaatt ctttgaattt tagtaataaa
    14101 aaagaggaac ggttgttcct cccatgatag gtaagtattc ttgtgaatgc ttgctttttt
    14161 gtggttgcaa tccgtttacg agaattgttt gtattgttct tgtttcaatt tactttatag
    14221 tgctttgaag ttggaatgct acactataac ttctaaaata tagtaaaatg aaccaaaaat
    14281 agtacacaat gtggtataat cttcttatgg catattcaat agattttcgt aaaaaagttc
    14341 tctcttattg tgagcgaaca ggtagtataa cagaagcatc atacgttttc caaatctcac
    14401 gtaatactat ttatggctgg ttaaagctaa aagagaaaac aggagagcta aaccaccaag
    14461 taaaaggaac aaaacc
//
LOCUS       DAVBEM010000051        14321 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVBEM010000051 DAVBEM010000000
VERSION     DAVBEM010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14321
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.051"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(114..1964)
                     /locus_tag="VQ548_001714"
     CDS             complement(114..1964)
                     /locus_tag="VQ548_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET2654523.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMVDFWGLSASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(2032..3171)
                     /locus_tag="VQ548_001715"
     CDS             complement(2032..3171)
                     /locus_tag="VQ548_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2654524.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKGKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDAEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGGLILKIDAHSKVTESFVMNNVAVIQQGEFVCGGPRP
                     TIVKGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLSLLTLLTLLKHK
                     NGFLIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKGTVIYLEK"
     gene            3229..4395
                     /locus_tag="VQ548_001716"
     CDS             3229..4395
                     /locus_tag="VQ548_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HET2654525.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TAMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            4534..4860
                     /locus_tag="VQ548_001717"
     CDS             4534..4860
                     /locus_tag="VQ548_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET2654526.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            4847..5440
                     /locus_tag="VQ548_001718"
     CDS             4847..5440
                     /locus_tag="VQ548_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HET2654527.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEVAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            5433..6344
                     /locus_tag="VQ548_001719"
     CDS             5433..6344
                     /locus_tag="VQ548_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HET2654528.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            6407..7471
                     /locus_tag="VQ548_001720"
     CDS             6407..7471
                     /locus_tag="VQ548_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654529.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(7543..8403)
                     /locus_tag="VQ548_001721"
     CDS             complement(7543..8403)
                     /locus_tag="VQ548_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HET2654530.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHIYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTETDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            complement(8525..9511)
                     /locus_tag="VQ548_001722"
     CDS             complement(8525..9511)
                     /locus_tag="VQ548_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HET2654531.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(9783..11258)
                     /locus_tag="VQ548_001723"
     CDS             complement(9783..11258)
                     /locus_tag="VQ548_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HET2654532.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(11362..12285)
                     /locus_tag="VQ548_001724"
     CDS             complement(11362..12285)
                     /locus_tag="VQ548_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2654533.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(12299..13228)
                     /locus_tag="VQ548_001725"
     CDS             complement(12299..13228)
                     /locus_tag="VQ548_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2654534.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(13547..13897)
                     /locus_tag="VQ548_001726"
     CDS             complement(13547..13897)
                     /locus_tag="VQ548_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654535.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETADKDVLENSQEELQKAVLFLADEKGSEHTEAELI
                     DNLKEVIAKLKANA"
BASE COUNT         4308 a         3071 c         2630 g         4312 t
ORIGIN      
        1 acggcaaggc gacgttgacg tgatttgaag agattttcga agagtataag tctctacata
       61 ataaaacgca tattaccaag gttatttaac ttgataatat gcgtttttct tttttattca
      121 atgtgggttg tttgattagc aaaggcgata atagcttgct tcaactcatc tccactgaga
      181 gtgcggaact ctccaatctt ttgattgatg gattctaaag gcatgacatt aaccttacca
      241 acgaaaatct tatccataac ttgattatca acgagttcgg ttgataccaa gagttcttcg
      301 tagagttttt cacctgggcg gattccaact tcaacgattg gaatttcact ttcagtgtgg
      361 ccacttagaa gcaccatctt cttggccaag tcataaatct tgactggttt gcccatatca
      421 aggataaaga cttccccatc tttggcataa gcaccagcat ggataaccag acggctagct
      481 tctggaatgg tcataaagta acgggtcatg cggaagtctg tcaccgttac aggcccacct
      541 tcagcaatct gacgttcaaa gactggaatg acactaccac ggctaccaag aacattccca
      601 aaacgaactg cacagtaggt tgattggcta cgttggttaa agccagtgac aatcaactcc
      661 gccacgcgct tggttgctcc cataacattt ggtggattga ctgccttatc tgtcgaaatc
      721 ataaccatct taggcacctt ggcttcatca acggctctag caacattgta agttccacgg
      781 atattgtttt tgaaggcttc ttttggattg cgctccatca taggaacatg cttgtgggct
      841 gccgcatgat aaacaatagc aggtttgtac tgctcaaaga cttgcaacaa acgatcatag
      901 tcttgaatgt ccgcaatcac aggtacataa tcaatccctt ggaacttacg aatcaattca
      961 tgataaacaa ggtagattga gttttcccca tgaccgagca agacaatgcg ttcaggattg
     1021 aagcgactaa cttgacgaca gatttcagaa ccgattgaac ctccagctcc tgtgactaag
     1081 atggtcttac ctgtcagttc tgcacccaga cgcgattcgt caagacggat ttcctgacga
     1141 cccaaaaggt ccgtaatatc aattttttgg aagccagtac ctgcttggtg aaggccctga
     1201 acaacagttt caaccttagg catcttgtaa catttgacac ccagcttatt acacatctgc
     1261 aagatacgct catattctga cggatccagc gacggaatcg caacgatgac acgctcgatt
     1321 tgatggcgtt tggctaattc aggcagattg tcataagagc ccaaaacagg aataccacca
     1381 agtttttgac cctttttctt agaatcctta tccaaaatac cgaccagttc taattcactg
     1441 gttggatgtt ggtaactatc cataaagaga gccccaccat caccggcacc aatcaagaag
     1501 gtccgacggt gttctccatc accactacct tttttgcgtc tggagtagat taactgccaa
     1561 gtaatccgtg gcaataaaat caagaaggta ctcaacaaga taaagagaat gataaaacgg
     1621 atggagaaga gtggcaagaa ggcataacag atactatatg acaagacact gctagcagtc
     1681 acaccaaaaa agattttcat gaaatccgta atcttgctgt aacgactaat actcgcgctc
     1741 aagccccaaa aatcaaccat caattgatag aacaggaagg ccaaactcgt atagataatg
     1801 tagtcaacag gtgctggatt aatcagccca taaaataaaa tataagatac aatgatggaa
     1861 accaccatac tgaaaatatc aaatattccc cagaaaacct gcttttgttg tttatttaaa
     1921 atttccacca gatcaatcac ataatctgtg agttttttat tcatagaaat ttactcctcc
     1981 ttaaaatagt tctactatat tgttattata gcacatttta atttatttgg cttatttttc
     2041 caaataaatt actgttccct tgtactcctt cttccattta aatcctctaa ttaaacctac
     2101 aatcgtccca aggccataag caaagtgaat ggaaaataaa agaaagggca tcacaattag
     2161 aaatccattt ttatgtttta ataaagtcag caaagtgagt aatgacagta atgataaaag
     2221 tagaaaatag gcacctaata gtaaagttat gaatacgaat gtgatcggta acaatgctag
     2281 actaaacaca agactcaaaa caaataaaca aggaacataa tgaaataatg ataaacactt
     2341 aaactgaaca tgacttgtca agccaatcca caaaccattt gaatactttt gatgcagcat
     2401 tttcttgaat gttggtcgaa tatactgata agatagaata cttgggctat agcggatttt
     2461 ataaccatgt tctcgaattc tataatgaat atcattatct tcagttcggc caagttgctc
     2521 atttactaaa ccaaccttct ggaaaacctc tcgtttatac atcccatgaa aaatagaaga
     2581 aacatatcta tcctcggaac tatttcgata attggcaatg ctactgccaa acatattttc
     2641 ctcaacaaga tgcaaggtct ctgcccattt tccttttcct ttgacaatcg tcggtctagg
     2701 ccctccacag acaaattcac cttgttgaat aacagccaca ttgttcatta caaaactctc
     2761 agtaactttt gaatgagcat caatttttaa aataaggccc cctacagaat gcttaactcc
     2821 caggttaaaa ccactagctt gatttttctt aggattgtta tacaatctaa ttgagttaaa
     2881 ctctgcatct tcttttataa attgctgaat gatagctgtg gtcccatctg tggacatagc
     2941 atttataaat agaatttcaa tattctcttt aggataggtt tgatttttta agtcttcaat
     3001 tagaccaggc agatattttt cttcattgta tgcactgatt acaatggata cgagaagact
     3061 ttcaacattt tgagtcacta ctactctcct gaattttccc ttccaccatt ctatcataat
     3121 tttcaagact tttccatttt tatcttgaaa gccagaaacc ttacttgaca ttatagtgaa
     3181 aaagccttaa aataagctgt tattaaaatc agctagaaga gatattatat gaaaaagcaa
     3241 tcactctttt ttgttccagg tattatcctg attggtgttt ccttgcgaac tccttttact
     3301 gttttaccca ttattttggg aaatatttcg caaggtctgg aggtagaagt tagttcgctt
     3361 ggtgtcttga ccagcctgcc tctccttatg tttaccctct tttcaccatt ttctacccga
     3421 ctggctcaga aaatcggctt ggagcatctc ttcacctaca gcctcttctt cttgaccatc
     3481 ggctcactta ttcgactaat caatctgccc ctgctctatc taggaacctt gatggttggg
     3541 gcaagtgtcg cagtcatcaa tgtcctgctt cctagtctta tccaagccaa tcaaccaaag
     3601 aaaattggtt ttctgaccac cttatatgta acgtctatgg ggattgcaac ggctctggct
     3661 tcctatctag ctgtgcccat tacacaagcc agttcttgga aaggacttat cctcctcctc
     3721 acgttactct gtctagcaac ttttttggtc tggctcccaa atcaccgcta taatcataga
     3781 ctagctccac aaaccaaaca aaaaagtcaa ataaaggtca tgcgtaataa acaggtttgg
     3841 gcaattatta tcttttcagg ttttcaatcc ttgatctttt acaccgccat gacctggtta
     3901 cctaccatgt ctatccatgc aggtctatcc agtcacgaag ctggcttgct gacttctatc
     3961 ttatctctga ttagcattcc tttttcaatg accatcccaa gcctgacaac cagtttatct
     4021 actcgcaacc gtcagctcat gctcactctg gtttcactag ctggtgtggt cggcatttcc
     4081 atgctctttt tcccaatcaa taatttcatt tactggcttg ccatccatct cctcatcgga
     4141 accgcaacca gcgccctctt cccttatctc atggtcaact tttcactcaa gaccagcgcc
     4201 cctgaaaaga cagcccaatt gtccggccta tctcaaacag gaggctatat cctagcagcc
     4261 tttgggccaa ccctctttgg ttacagtttt gacctattcc actcttgggt accagctgta
     4321 gctgccctct tgctcatcga tatcctgatg actgtggccc tctttacagt ggacagagcg
     4381 gataagatcc tttaaacttc tagttttagc tagaagtttt ttatatataa aaattttaca
     4441 catttctctt gacagggctt tcttttagat gtacaatgta tgtgtagaaa aattatatat
     4501 aaaaatctta cacattagaa aaggaggttt cccatgtact ttccaacatc ctctgccttg
     4561 attgaatttc tcatcttggc tgtactggag cagggtgatt cttatggtta tgagattagc
     4621 caaaccatta agctgatcgc taatatcaaa gaatccacac tctatcccat tctcaaaaaa
     4681 ttggaaggca atagctttct gacaacctat tctagagagt tccaaggtcg catgcgcaaa
     4741 tactactcct tgacaaacgg tggtatagag cagctcttga ccctaaaaga tgaatggaca
     4801 ctctatacag acaccatcaa tggcatcata gaagggagta tccgccatga caagaactga
     4861 atacctgact cagctagaac tctatctcaa gaaactacct gaagctgacc gtatcgaagc
     4921 catggactat ttcagagagc tctttgacga tgctggagtc gaaggagaag aagaactcat
     4981 cgctagtttg ggaactccca aagaagtggc ccacgaagtt ctatccaatc ttctcgataa
     5041 aaaaatcaat gaagcacccg ctcaaaaaaa taaccgacaa attttacata tcgccttgtt
     5101 agccctcctt gcagcaccta tcggcattcc tctgggaatc gccatcctcg tgaccctgtt
     5161 cgcaatcctt gtagccgctt tgactgtcat tctggctttc tttgcagttt ccatactggg
     5221 tatcatcggc ggattcctat ttttagttga aagtttcact gtcctcgccc aagccaaatc
     5281 agcctttatc ttgatttttg gttctggttt actggctatc ggtgcttctt cgctagtttt
     5341 acttggcatt tcctatgtag ctcgcttctt cggtctactc attgttcgtc tggtacaatt
     5401 tgttcttaaa aaaggaaaga gaggtaatca gcatgcgtaa atggacaaaa ggatttctca
     5461 tctttggtgt ggtgactacc gttatcggct ttatcctgct ttttgtaggt atccaatctg
     5521 acgggattaa gagcctactt tccatgtcca aagaacctgt ctatgatagc cgtacggaaa
     5581 agctaacctt tggcaaggaa gtcgaaaacc tagaaattac tctccaccaa cacacgctca
     5641 ccatcacaga ctctttcgat gatcaaatcc acatttctta ccatccatct ctttctgctc
     5701 accatgatct tatcaccaat cagaacgata gaactctgag tctcactgat aagaaactgt
     5761 ctgaaactcc gtttctctct tctggaattg gtgggattct tcatatcgca agtagctact
     5821 ctagtcgttt tgaagaagtt attctccgac taccaaaagg gagaactcta aaagggatca
     5881 acatctcagc caatcgcgga caaaccacca tcataaatgc tagccttgaa aatgcgaccc
     5941 tcaatacaaa cagctatatc ctccgaattg aaggaagtcg tatcaaaaac agtaaactca
     6001 caacgcccaa tatcgttaat atctttgata cagttcttac agatagtcag ctagagtcaa
     6061 cagagaatca cttccacgct gaaaatatcc aagtccatgg taaggttgaa ctgactgcca
     6121 aagattatct cagaatcatc ctagaccaga aagaaagcca acgaattaac tgggacatct
     6181 caagcaacta tggttctatc ttccaattca caagagaaaa gcctgaatca agaggtacgg
     6241 aattaagcaa cccttacaaa actgaaaaaa ccgatgtcaa ggatcaactc attgcgagat
     6301 ctgatgataa tattgatcta atatccacac caagcagacg ttgacaaaaa cgcttacatc
     6361 tgctactatg gaagcatatt tatctaacta aaaaggaggt tctaccatga aacaagaatg
     6421 gtttgaaagt aatgattttg taaaaacaac aagcaagaac aagcctgaag agcaagctca
     6481 agaggttgca gacaaggctg aagaaacgat agccgatctc gatacaccaa ttggaaaaaa
     6541 tactcaagta gaggaggaag tctctcaagc tgaagtcgaa ctggaaagcc agcaagaaga
     6601 gaaaattgaa actcctgaag gcggtgaagc gagaacagaa atagaagaaa agaaggcatc
     6661 taattctact gaagaagagc cagacctttc taaagaaaca gaaaaagtca ctatagctga
     6721 agagagccaa gaagctcttc ctcagcaaaa agcaaccacg aaagagccac ttcttatcag
     6781 taaatcttta gaaagtcctt atatccccga ccaagctcca aaatctaggg ataaatggaa
     6841 agagcaagtg cttgattttt ggtcttggct agtggaagcg atcaaatctc ctacaagtaa
     6901 gttggaaaca agtatcacac acagttacac agcctttctc ttgctcattc tgttttctgc
     6961 atcttccttt ttctttagta tctatcacat caaacatgct tactatggac atatagcaag
     7021 cattaacagt cgcttccctg agcagctagc tcctttaact cttttttcta tcatctctat
     7081 cctagtagcg acaacactct tcttcttttc attcctcttg ggtagtttcg ttgtgagacg
     7141 atttatccac caggaaaagg actggacgct agacaaggtt ctccaacaat atagtcaact
     7201 cttggcaatt ccaatcttcc tcactgctat tgctagtttc tttgctttct ttgatagcct
     7261 acgatttacg gccctcttgt gtgtgattag cattggaatc attctgcttg ccagtctcca
     7321 tatcattaca agaccaagtc aagcaagtga aaccgactcc ttctatcaat tattcttgtc
     7381 tgtccttgtg aacggagtta ttatcctcct cttctttgta gctgaagtgg cactgattgg
     7441 agattatctt cgtatcttgg cctttcttta aaattcaatc ctgtcatcct tggcaggatt
     7501 ttttctatgt caaaaaagca agtcgattga cctgcttctg ctttactttt cttgtgctaa
     7561 tgttttaaaa tctttgtcta atatgggttg cacttctatt tgattggcgt ctagttggtg
     7621 gtaaaaagat gggggtaata cctctaagaa ttttgcatag tccaagcgag caatggcttc
     7681 atagtcttct ggtttagagc catctcctgt gatttgaacc aagtcaatct cccactgcac
     7741 ttccttatcc accaattgct caatataggc tgcaggaaca aacggttctc tcggtaaaac
     7801 tgtcttgact ccttgagcta gatggtaaac gccatgcact tttccttctc catcctgata
     7861 gaaggaaact ctcgcaaagt aggcatctgt ctcttgaacc gcacgcacac gcgcttcaaa
     7921 ctgagccaaa ccatctgcct ctaaaaagct tttcaagttc tcacgactaa agaaaatagg
     7981 attaaaaatt ccttggcaaa tcgtaaaacg agctacaggg tctgctagat aggcttgaat
     8041 acttgcttgg aaataagctt caaaatcaaa accatctagc ccttcaatat cagtccctgt
     8101 ataagcaagc aaagcatcta aaaatgactt gataatctgc cagtctgtct ctgttagtag
     8161 gtcaggaaga tcgacacggt aagccttttg accatcagca taactgacct taaaaagaaa
     8221 ttgtgattgc cccactatcg cacactcaat atactcgaga cgattaagag gctgacggag
     8281 atagactaca tcatagatat gtgactccaa accgtctagc aatgccaaga tcgacttggc
     8341 attcaaaatc tcttgttctc ctaaaatgct ctgtttattt ggaataaaaa atgttttcgc
     8401 cataactgga ctcctttgaa atcgcttaca tacagtatac cttatttttc tgaaagatac
     8461 agaaacaaac tttagatttt tgagtacaaa gcatagaaaa acagcccctg aggactgttt
     8521 gatcttatac agtagctgct tgatccaagc tttcaccgat agcggctagg cgctcgatca
     8581 cttcagcttg tgtcaattca ttttttgaaa catagcggtt acgtgggtga acacggcact
     8641 cgtgtgagca tccacgaagg tacttgtctt cattttcttc tgatgtcaag atacgacggt
     8701 tacagaaggg atttccacag ttgacataac gttcacatgg tgttccatca aaccagtctt
     8761 tccctacgat ggttgggttg acatggttga catcaacggc gatacgctcg tcaaatacgt
     8821 acatttttcc atcccaaagc tcaccttgaa cttctgggtc tttaccgtaa gttgcgattc
     8881 ctccgtgcaa ttggccgaca tctttgtagc cttcacggac catccagcct gagaatttct
     8941 cacagcgaac gccacctgta cagtaaacca cgacacgctt gtccatgaat ttttccttgt
     9001 tatcacggac ccattgtggt aactcacgga agttgcgaat atctgggcga atagctccac
     9061 ggaaatgtcc taggtcgtac tcataatcgt tacgtgtgtc aaggacaacg gtatctttat
     9121 caagaagcgc ttctttgaac tcttttggag acaagtaagc acctgttgtt tcaagtgggt
     9181 tgatgtcatt gtcaaagtcg ttgtcttcca aaccaaggtg gacaatttct ttcttgtagc
     9241 gaacaaacat cttcttgaag gcttgttcat tttcttcgtc aatcttgaac cagagttctt
     9301 ccattcctgg aaggctgtga acgtagtcca tgtatttttg agttgtttca tagtcacctg
     9361 aaactgttcc gttaattccc tcgtcagcga ctaggatacg gcctttaaga ccgattgatt
     9421 tacagaaagc caagtggtct gcagcaaatt gctctgcatt ttcaattgga gtataaaggt
     9481 agtaaagtaa gacacgaata tcttttgcca taagatttgt tctcttttct attcttaaat
     9541 tttctaaatt ttttatttat ccatactagt atacctgctt gagaaaacga atgcaattta
     9601 tttgactgga aattgtagag gattctcgaa atttcctgaa tggttaaaat aaggacaaga
     9661 gaaaacatgg atatctatat ccttgtgcca aaaaaaccac tgccctcccc agaccaacct
     9721 gaggaaagca gtgattctta ttttaggagt taggaatgaa tacacgaaat caatttagct
     9781 gattattttt tgtttttcaa gaattcatcg tattgttttt gcatttcgtt caatactttt
     9841 tcgtaggcac cttcagattt caatttttcc atcaattctg gaatcgcttt atctgggtct
     9901 acagtaccag tgttgatagc tgtatcaaat tgttgcattg tgttagcaat agctgagatt
     9961 tcagatttca cattgtcagt attgaagata aatccaagcg ctggagattc tttagcttct
    10021 gccaattctt tcttagaatt ttcgatttgt tggtctgtaa cgttttcgtt gatgtaaagg
    10081 atccagttgt taccagtgtt ccatccaccc atgtgagtgt ttcctttgta gccatcaaga
    10141 acgcgaacac ggttttcttt accttcaatt ttttcccagt tcttgccttc tggaccgtaa
    10201 acaagaccgt tcaaaagttc tgggttcgta ttcaagaggt tcaagatttc cattgatttt
    10261 tctttgttct tagagttgtt tgagatgaca aagttagcaa cttgtgttgt ttggtttttc
    10321 ttgatgaagt tagtgattgg tttgatttgg atatctttgt tggcaacacg tgaaagcaag
    10381 ctgttaccgt agtcagctgg tcctactgtt tcttcacgaa cgaaccaagt atcttgttga
    10441 aggtcaaatg aagtatcgct tgttgcgacg tcttttggaa tgtagccagc ttcatagaat
    10501 ttgtgaagag tcttcaagtg ttctttgaaa cgaggcactt cgtaacggtt tacaacttta
    10561 gtagtatcgc cttcaaggtc aataacgaat ggaagcccgt ttgctactgg gtagtcaaaa
    10621 ttatcagatg ggatgaaaac tttaccaata gcaaatggta ctacgtctgg agctttttct
    10681 ttgatttgtt tcaagactgg ctcaagagtt tcgtaagaag taacacctga aatatcgata
    10741 ccatatttgg caaggagagt tccgttgaag gcaaagtttt gagatgatgc tacgttggct
    10801 gcaactggta cagcataaat cttaccattt acagtattac ccttgatata agctggatca
    10861 agtgccttgt aaaggtcttt accttctttt ttgtacaatt ctgtcaagtc agcataagca
    10921 cctttttgag catttacaat atagttatct gcaaaggcga tatcatagtt ttcaccagat
    10981 gatgtgataa ctgacatttt cttaccatag tcaccccagc caaggtattg gatatccaat
    11041 ttggcaccaa ctttttcttc gatgattttg ttggcatttg ctaacaattc atccaagtta
    11101 tctggtttgt caccgatttg gtacattttg ataacaggtt tgtcacctga atcagcagct
    11161 tttttgctgt tacctgtcaa atttccacaa gcagcaagac ctgcagccag agcgactaca
    11221 ctagcagatg caaaagcata ttttttccag tttttcatga taaaaactcc tttttttatt
    11281 tttaaactta taaacaatgt aatgatctta acttcacaca agggaagttg ggaactgaga
    11341 aatgttcttt ttcaataagc actattcttt cacaccaccg atagtcaaac cttttacaaa
    11401 gtagcgttgg aagaatggat acaaaatcgc gattggaagg gttgctacca caaccatggc
    11461 catacgacct gtttctttcg gtagagcaac tcccagttga ccagtcaagc cgaccgcttt
    11521 ggcaatgtag tccatatttt gttggatttg catgagcaaa tattgcaatg gatacaagtt
    11581 atcactcttg atgtaaagaa gggcgttgaa ccagtcattc cagaaaccaa gagctgtcaa
    11641 aagcgtgatg gttgcgatac ctggtagtga caatggcaaa cagatttgga agaaaatccg
    11701 agcctcactg gcaccatcga tacgagccga ttcgagaatg gcttctggaa tggtcttctt
    11761 gaaaaaagaa cgcatcaaga tgatattgaa tggtgagaga agcattggaa caatcaaggc
    11821 ccaaacagtg tcaccaagct gaagtacacg ggtcaccatg atataacctg gtaccaaacc
    11881 agcgttgaac aacatactga gaaggacgaa gatggtaaaa aatctgcgat acttaaaggt
    11941 tgtccgtgaa atagcgtagg cataggttgt tgtgataaag acatttgtca atgtcccaac
    12001 tacggttaca aagacagaga tgaagagggc ttgtaggatt ttatccttaa actgtgccaa
    12061 aaactcaaaa ccgtctaagc caaattggga tgggaagaag ctatagccgt attggaggag
    12121 gcttttctcg tctgtcactg aaataatgat aacgaataca aaaggtagga tacaagagag
    12181 ggcaatcaaa cccgaaatga tactgaagaa gatatctgct ttcttactga aggagtgaat
    12241 gccgacatta tcaatttttt cttttttaat tttctttttt gccatattct cctcctttct
    12301 agaacaaagc tgagtttgga tcgactcgtc ttgcaagcaa gtttgatagg ataaccagaa
    12361 tcaaaccaac aacggattgg taaagaccgg ctgctgcagc cataccgata tctgctgtct
    12421 gagtcaaacc attaaagaca tatacgtcca aaacgttggt tacattgtaa agctgaccag
    12481 cattgtgtgg gatttgatag aagagaccga agtctgcgcg gaagatattt ccgactgcaa
    12541 ggatggtcaa tacagttaca agcggagtca actgaggaat ggttacgttg cgaatacgtt
    12601 gccacttgct agctccgtcc actgtcgctg cttcgtagta ggttggatca attcccatga
    12661 tcgtcgcata gtacatgaca ctgctatatc caaagccttt ccaaatacct aggaaaagta
    12721 ggagataggg ccagatgccc aggtcagcgt agaaattgac ttctttgaga ccaagacttt
    12781 ccaatagatg attgaacacc cctttatcaa tatttaggaa ggcatctgta aagaaactga
    12841 tgataaccca agacaagaag taagggaaca acatagaagt ttgaaaaatc ttcaccattc
    12901 tcttagaacg gagctcgctg aggataatgg caatccctac agatacaact aaacctagaa
    12961 agataaagcc aagattgtag aggacagtat ttcgtgtgat aataaaggcg tctcttgaac
    13021 taaataagaa tctgaaatta tcgagtccga cccatttact atttatgata ctatctatga
    13081 aaccattact ggtcatgtgg tagtctttga aggcaaccac gttcccaaat actggaatgt
    13141 aaaagaatag aatcaaccag agtgcccctg gcaaaaccat caagagaaag atccagttgt
    13201 ctctcaatgt ttttgaaaac tttttcataa tttcctccct ttttattttg atatccatct
    13261 aaaaattctt ttttagactt ttgataacga ttacattatt agtatactcc tatttgcagg
    13321 ttaggttaaa ctcctaatta tagaaaaaac tccacaaatt atgtagcaga tttaaaactt
    13381 tatcaccact atcaaacaaa tgtcctaaat caattgttta ttttatctct attagcccag
    13441 tgatggcgtc actctgttat aagcatccaa caacggggta tactgaaaaa tctccagact
    13501 agggaactca gcgatagttc ctaatctgga gatttttaat atgttattag gcgtttgctt
    13561 tcaacttagc aataacctct ttaagattat caatcaactc tgcttcagta tgctcagagc
    13621 ctttttcatc tgccaagaac aaaactgctt tttgaagttc ttcttgagag ttttcaagga
    13681 catccttatc tgctgtttct ttgcccgctg tttgtcctcc atccttagtt gctgactggc
    13741 tttccttaat ggactctagg gaagcaatgg catctttgac tgtttgcaag atatcacgta
    13801 aaccttgctc tgtcaaacta tcatctgcaa aagctttctt agcctctgcc aaaaccagac
    13861 gtgctgaatc tgtggtagga ttcgatacac ctgtcaatga tctcaaaaga ttttctaaag
    13921 tttgagtctg cttactaata ctagactaaa atcaaaaagc attatataac agtgatatga
    13981 aatcaactaa agaagaaatc caaactatca aaacactttt aaaagactct cgtacagcta
    14041 aatatcataa acgccttcaa atcgttctat agtaaaatga aacaagaaca ggacaaatcg
    14101 atcaggacag tcaaatcgat ttctaacaat gttttagaag tagaggtgta ctattctagt
    14161 ttcaatccat tatatttcgt ctgatgggca aatcttataa agagattata gaacttttat
    14221 agtagtttga aataagatgt gaacaactct atcaggaaag tcaaattaat ttatagaaat
    14281 attttagcag ctaaggtgta ctgttataga ttcaatacac t
//
LOCUS       DAVBEM010000052        14107 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVBEM010000052 DAVBEM010000000
VERSION     DAVBEM010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14107
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.052"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            <1..90
                     /locus_tag="VQ548_001727"
     CDS             <1..90
                     /locus_tag="VQ548_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET2654536.1"
                     /translation="ISTTYRNHRKHFGLRMNLIAGIINHELGF"
     gene            complement(426..2117)
                     /locus_tag="VQ548_001728"
     CDS             complement(426..2117)
                     /locus_tag="VQ548_001728"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HET2654537.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2253..2699
                     /gene="argR"
                     /locus_tag="VQ548_001729"
     CDS             2253..2699
                     /gene="argR"
                     /locus_tag="VQ548_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2654538.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2750..5284
                     /gene="mutS"
                     /locus_tag="VQ548_001730"
     CDS             2750..5284
                     /gene="mutS"
                     /locus_tag="VQ548_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HET2654539.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKLDSQNNFLVAIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSCQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPALAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTENPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5431..7125
                     /gene="patA"
                     /locus_tag="VQ548_001731"
     CDS             5431..7125
                     /gene="patA"
                     /locus_tag="VQ548_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HET2654540.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDVPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(7455..7724)
                     /locus_tag="VQ548_001732"
                     /pseudo
     CDS             complement(7455..7724)
                     /locus_tag="VQ548_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            7916..9682
                     /gene="patB"
                     /locus_tag="VQ548_001733"
     CDS             7916..9682
                     /gene="patB"
                     /locus_tag="VQ548_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HET2654541.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTHVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            9821..10510
                     /locus_tag="VQ548_001734"
     CDS             9821..10510
                     /locus_tag="VQ548_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET2654542.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLDEL"
     gene            10514..10693
                     /locus_tag="VQ548_001735"
     CDS             10514..10693
                     /locus_tag="VQ548_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654543.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            10680..12029
                     /locus_tag="VQ548_001736"
     CDS             10680..12029
                     /locus_tag="VQ548_001736"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HET2654544.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            12153..13613
                     /locus_tag="VQ548_001737"
     CDS             12153..13613
                     /locus_tag="VQ548_001737"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HET2654545.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            13627..14061
                     /locus_tag="VQ548_001738"
     CDS             13627..14061
                     /locus_tag="VQ548_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET2654546.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNTYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         4125 a         2722 c         3182 g         4078 t
ORIGIN      
        1 atttcaacaa cctatcgaaa tcatcgtaaa cacttcggat tacgaatgaa tttgattgct
       61 ggcattatca atcatgaact aggattctag ttttgcagga agtctattat ttggttaggt
      121 gaattagtga agcgtttagg caagtgtctc tggttacgac gtcatggact ctaaatcgat
      181 tatatttagg ggtcatgact agtgaagcag ttagctagtt cgcatataag cggctagcgt
      241 ctaacaatta ggaactttag ttccaataac tttaagatta cgacgtttta ggacataaat
      301 cgatcatatt tatgtcctaa aactagtgaa gtatgtccta aaactagtga agcgcctagc
      361 caaagtccga ataggatttg gcgttagtta cttagattgc tttgcaatca agtaactttg
      421 gcgatttaca tcttctctgg cgcttctact ccaagcaagc gaagggcttc tttgagaacg
      481 actgcggttg cgtagctgag ggctagacgg ctgtcgcgtt ctgggctttc atccaagata
      541 cgtgtatgtg catagtattt gttaaaggat tgagccaggc taattgcaaa tttagcaatg
      601 atagaaggtt caaagttatc tgccgcacgg ttgataatac gtgggaagtc ttgaatgagt
      661 ttaatgattt cccagctttc agtatcattc aagctatagt tgccagctgt ttctggtttg
      721 aaatcggctt tgcgtaagat agattggata cgagcgtagg catattgaac gtaaggtcca
      781 gtttcaccct cgaaggatac catagcctct aggtcgaagt cgtatccatt tgtacggtcg
      841 gttttgaggt catagaattt aatggctcca accccaacag catgtgctac ttggtctttg
      901 ttttctagtt caggattttt agcctcgatt tggaccttgg cacggctaac agcctctgca
      961 acagtaggct ctagcaagat gacattccct ttacgagtag agagtttctt cccttctttt
     1021 gtaaccaaac caaaaggaac gtgagtaatg tcgtcactcc agtcgtagcc catctcttgc
     1081 aagacagctt tgagctgttt aaagtgggca gattgttctt gaccaacgac atagatagat
     1141 ttagcaaatt ggtattcgtt tttacggtag agggctgcag ccaagtcacg tgtgatatag
     1201 agagttgcac catcagactt cttgatgagg gctggatgtt caattccgta tttctcaaga
     1261 ttcacaactt gggcaccttc tgattcaaga agtagtcctt tttcagaaag aatgtctaca
     1321 actgcatcca tcttatcatt gtagaaggct tctccgttat agctgtcaaa ttcaaccttc
     1381 aattcattgt aaaggcggtt aaattccact aaactttcat cgcggaacca ttgccaaaga
     1441 gcgagagctt cctcatctcc attttcaagt ttacggaacc attcgcgcgc ttcttcatcc
     1501 aagctagggt cattttcagc ttcagcgttg atgcggacat agagtttaag gagttcatcg
     1561 attggatgag cttttacagc ttcttcgtcg ccccattttt tgtaggcaac aatcaacatc
     1621 ccaaattgtt taccccagtc tcccaaatgg ttgaccttga ccgtttgata accgattttt
     1681 tggaaaatat gtgacaagct atctccgata acagttgaac gcaggtggcc aatagaaaat
     1741 ggtttagcga tattcggact agacatgtcg ataacaacat tttcttgttt accaatattt
     1801 tggtcagcat agtgttcttt ttcagtggta acagcttgca atacttgagc agaaatggca
     1861 gatttatcaa ggaaaaagtt aacgtaaggt cctgttgcga caactttttc aaaggcttgg
     1921 ctgttcattt tttcagccag ttcagccgca atcatttgtg gtgctttacg ttcgactttg
     1981 gcaagagaaa aagcagggaa agcgatgtca cccatttctg agtttttagg ggtttccagt
     2041 aactttaaaa tagcctcttg gtccaggcta tcaatgatgc tagccaattc gctagcaatc
     2101 aattcttttg tattcattaa gagctccttt ttggactttt ctactatttt atcacaattt
     2161 taaagaaaga agaaaaaatt tttgaaatct cctgtttttt tggtataata tggttataaa
     2221 tatagttata aatatgcacg caagaggatt ttatgagaaa aagagatcgt catcagttaa
     2281 taaaaaaaat gattactgag gagaaattaa gtacacaaaa agaaattcaa gatcggttgg
     2341 aggcgcacaa tgtttgtgtg acgcagacaa ccttgtctcg tgatttgcgc gaaatcggct
     2401 tgaccaaggt caagaaaaat gatatggtgt attatgtact agtaaatgag acagaaaaga
     2461 ttgatttggt ggaatttttg tctcatcatt tagaaggtgt tgcaagagca gagtttacct
     2521 tggtgcttca taccaaattg ggagaagcct ctgttttggc aaatattgta gatgtaaata
     2581 aggatgaatg gattttagga acagttgctg gtgccaatac cttattggtt atttgtcgag
     2641 atcagcacgt tgccaaactc atggaagatc gtttgctaga tttgatgaaa gataagtaag
     2701 gtcttgggag ttgctctcaa gacttatttt tgaaaaggag agacagaaaa tggcgataga
     2761 aaagctatca cccggcatgc aacagtatgt ggatattaaa aagcaatatc cagatgcttt
     2821 tttgctcttt cggatgggtg atttttatga attattttat gaggatgcgg tcaatgctgc
     2881 gcagattctg gaaatttcct taacgagtcg caacaagaat gccgacaatc cgatccctat
     2941 ggcgggtgtt ccctatcatt ctgcccaaca gtatatcgat gtcttgattg agcagggtta
     3001 taaggtggct atcgcagagc agatggaaga tcctaaacaa gcagttgggg ttgttaaacg
     3061 agaggttgtt caggtcatta cgccagggac agtggtcgat agcagtaagc tggacagtca
     3121 gaataatttt ttggttgcca tagaccgcga aggcaatcaa tttggcctag cttatatgga
     3181 tttggtgacg ggtgactttt atgtgacagg tcttttggat ttcacgctgg tttgtgggga
     3241 aatccgtaac ctcaaggctc gagaagtggt gttgggttat gacttgtctg aggaagaaga
     3301 acaaatcctc agctgccaga tgaatctggt actctcttat gaaaaagaaa gctttgaaga
     3361 ccttcattta ttggatttgc gattggcaac ggtggagcaa acggcatcta gtaagctgct
     3421 ccagtatgtt catcggactc agatgaggga attgaaccac ctcaaacctg ttatccgcta
     3481 cgaaattaag gatttcttgc agatggatta tgcgaccaag gctagtctgg atttggttga
     3541 gaatgctcgc tcaggtaaga aacaaggcag tcttttctgg cttttggatg aaaccaaaac
     3601 ggctatgggg atgcgtctct tgcgttcttg gattcatcgc cccttgattg ataaggaacg
     3661 aatcgtccaa cgtcaagaag tagtgcaggt ctttctcgac catttctttg agcgtagtga
     3721 cttgacagac agtctcaagg gtgtttatga cattgagcgc ttggctagtc gtgtttcttt
     3781 tggcaaaacc aatccaaagg atctcttgca gttggcgact accttgtcta gtgtgccacg
     3841 gattcgtgcg attttagaag ggatggagca acctgctcta gcctatctca tcgcacaact
     3901 ggatgcaatc cctgagttgg agagtttgat tagcgcagcg attgctcctg aagctcctca
     3961 tgtgattaca gatgggggaa ttatccggac tggatttgat gagactttag acaagtatcg
     4021 ttgcgttctc agagaaggga ctagctggat tgctgagatt gaggctaagg agcgagaaaa
     4081 ctctggtatc agcacgctca agattgacta caataaaaag gatggctact attttcatgt
     4141 gaccaattcg caactgggaa atgtgccagc ccactttttc cgcaaggcga cgctgaaaaa
     4201 ctcagaacgc tttggaaccg aagaattagc ccgtatcgag ggagatatgc ttgaggcgcg
     4261 tgagaagtca gccaacctcg aatacgaaat atttatgcgc attcgtgaag aggtcggcaa
     4321 gtacatccag cgtttacaag ctttagccca aggaattgcg acggttgatg tcttacagag
     4381 tctggcggtt gtggctgaaa cccagcattt gattcgacct gagtttggtg acgattcaca
     4441 aattgatatc cggaaagggc gccatgctgt cgttgaaaag gttatggggg ctcagaccta
     4501 tattccaaat acgattcaga tggcagaaga taccagtatt caactgatta cagggccaaa
     4561 catgagtggg aagtctacct atatgcgtca gttagccatg acggcggtta tggcccagct
     4621 gggttcctat gttcctgctg aaagcgccca tttaccgatt tttgatgcga tttttacccg
     4681 tatcggagca gcagatgact tggtttcggg tcagtcaacc tttatggtgg agatgatgga
     4741 ggccaataat gccatttcgc atgcgaccaa gaactctctc attctctttg atgaattggg
     4801 acgtggaact gcaacttatg acgggatggc tcttgctcag tccatcatcg aatatatcca
     4861 tgagcacatc ggagctaaga ccctctttgc gacccactac catgagttga ctagtctgga
     4921 gtctagttta caacacttgg tcaatgtcca cgtggcaact ttggagcagg atgggcaggt
     4981 caccttcctt cacaagattg aaccgggacc agctgataaa tcctacggta tccatgttgc
     5041 caagattgct ggcttgccag cagacctttt agcaagggcg gataagattt tgactcagct
     5101 agagaatcaa ggaacagaga atcctcctcc catgagacaa actagtgctg tcactgaaca
     5161 gatttcactc tttgataggg cagaagagca tcctatccta gcagaattag ctaaactgga
     5221 tgtgtataat atgacaccta tgcaggttat gaatgtctta gtagagttaa aacagaaact
     5281 ataaaaccaa gactcactag ttaatctagc tgtagcaagg agacttcttt gacaattctc
     5341 cacttttttg ctagaatgac atcacacaaa cagaatgaaa aggagctgac gcattgtcgc
     5401 tcccttttgt ctatttttta aggagaaagt atgctgattc agaaaataaa aacctacaag
     5461 tggcaggccc tggcttcgct cctgatgaca ggcttgatgg ttgctagttc acttctgcaa
     5521 ccgcgttatc tgcaggaagt cttaggcgcc ctccttactg ggaaatatga agctatttat
     5581 agtatcgggg cttggttgat tggtgtggcc gtagtcggtc tagttgctgg tggactcaat
     5641 gttgtcctcg cagcctatat tgcccaagga gtttcatccg accttcggga ggatgccttc
     5701 cgtaaaattc aaaccttttc ttatgctgat attgaacaat ttaatgcggg aaatctagtc
     5761 gttcgaatga caaatgatat caaccagatt cagaacgttg tcatgatgac cttccagatt
     5821 cttttcagac ttcccctctt gttcatcggt tcgtttatcc tagcggttca aaccttacct
     5881 tctctgtggt gggtgattgt tctcatggta gtcttgattt ttggtttgac tgctgtcatg
     5941 atgggaatga tggggcctcg ttttgccaag tttcaaaccc ttcttgagcg catcaatgcc
     6001 attgccaagg aaaatttacg tggcgttcgt gtggtcaagt cctttgtcca agaaaaagag
     6061 caatttgcta agtttacaga ggtctcagac gagcttcttg gtcaaaacct ttacattggt
     6121 tatgcctttt cagtagtgga accctttatg atgttggttg gttacggggc ggtcttcctc
     6181 tctatttggc tggtcgcggg aatggttcag tcggatccgt ctgttgttgg ttccatcgct
     6241 tcttttgtta attacctaag ccagattatc tttaccattg ttatggttgg atttttggga
     6301 aattctgtca gccgtgccat gatttccatg cgtcgtattc gagaaattct tgacgcagag
     6361 ccagctatga ccttcaagga tgtcccagat gaagagttgg ttggaagcct tagctttgaa
     6421 aatgtgacct ttacctatcc aatggacaag gaaccgatgc tgaaagatgt gagctttact
     6481 attgaacctg gtcaaatggt tggtgtagtt ggagcgactg gtgcaggaaa gtcaaccttg
     6541 gctcaattga ttccacgtct ctttgatcca caggaagggg ctatcaaaat cggaggtaag
     6601 gatattcgag aagtgagtga aggaaccctg cgtaaaacag tttccatcgt tctccaacgt
     6661 gccattcttt ttagtggaac gattgcagat aacttgagac aggggaaggg aaatgctact
     6721 ctatttgaaa tggagcgcgc agccaatatt gcccaggcta gtgaattcat tcatcgtatg
     6781 gagaaaacct ttgaaagtcc agttgaagaa cggggaacca atttctctgg tggacaaaaa
     6841 caaaggatgt cgattgcgcg tgggattgtc agcaatccac gtattctgat ttttgatgat
     6901 tcgacctcag ccttggatgc caaatcagag cgcttggtgc aagaagcttt gaataaggac
     6961 ttgaagggga cgacaaccat tattattgct caaaaaatta gctcggttgt ccatgcagac
     7021 aagatcttgg ttctaaatca aggacgattg attggtcaag gcacgcatgc agacttggtt
     7081 gccaacaatg ccgtttaccg tgaaatctat gaaacacaga aatgaaagac aaactataag
     7141 aaaagtcaat agttttatct aaactatttc ttatttcaat ttgatgattt ggcgatgatt
     7201 ttagagcacg gcaaaaagcc cttgaaaaag tccatttttt caaaggtaat cctgtgttga
     7261 tttcagaaat tacatcactt tttgttcgtc aaatggcagc tcttttttag gatataaaac
     7321 agggttcgga taagtttttt tgcaaggtgg atgatggcta cattgtaatg ttttccttgt
     7381 tataacttag tcttaagata ggccttaaaa gcaggtgaaa agtgagggca tgctttggca
     7441 gcttgtatga gtacctaccg cagatgaggg gaaccccgtt tgaccattct tccagctaaa
     7501 tcaatctgac ctgactgata aatagaagaa tccagtccag cgaaagcttg taattgagca
     7561 ggattatcaa aggcatgaat atttcgaatc tcggctaaaa tgaccgcccc taaacgattc
     7621 ccaatcccag taaccgtcgt gatgaccgag ttgaactcag ccatcaagtc attgacacat
     7681 ttttccgcct tgtcaatgag cctcttgtaa tgtttgatga tttcattaca cgagataaaa
     7741 cgtctatgcg ttatcaaact cattaccaat taaaacaaaa agctgtggtt agatcctttc
     7801 ggaaatcgtc aagcgattgg aggaaatgaa ctaatccaca gcggcttatt ccaagtatac
     7861 cacttgggct ttggcagtag ctaactgcgc taaatataat ataaggagga gtaaaatgaa
     7921 gacagttcaa tttttttggc attattttaa ggtctacaag ttctcatttg tagttgtcat
     7981 cctgatgatt gttctggcga cttttgccca agccctcttt ccagtctttt ctggacaagc
     8041 ggtgacgcag ctagccaatt tagttcaagc ttatcaaaat ggcaatccag aacttgtatg
     8101 gcaaagccta tcaggaatca tggtcaatct tggcctgctg gttttggttc tatttatctc
     8161 tagtgtaata tacatgtgtc tcatgacgca cgtgattgca gaatcgacca acgagatgcg
     8221 caaaggcctc tttggtaagc ttgctcagtt gacggtttct ttctttgacc gtcgacaaga
     8281 tggcgatatc ttgtctcatt ttaccagtga tttggataat atcctccaag cctttaacga
     8341 aagcttgatt caggtcatga gcaatattgt tttatacatt ggtctgattc ttgtcatgtt
     8401 ttcgagaaat gtgacgctgg ctctcatcac cattgccagc accccattgg ctttccttat
     8461 gctgattttc atcgtgaaaa tggcacgcaa atacaccaac ctccagcaga aagaggtagg
     8521 gaagctcaac gcctatatgg atgagagcat ctcaggccaa aaagccgtga ttgtgcaagg
     8581 aattcaagag gatatgatgg caggatttct tgaacaaaat gagcgcgtgc gcaaggcaac
     8641 ctttaaagga agaatgttct caggaattct tttccctgtc atgaatggga tgagcctgat
     8701 taatacagcc atcgtcatct ttgctggttc ggctgtactt ttgaatgata agtctattga
     8761 aacaagtaca gccctaggtt tgattgttat gtttgcacaa ttttcacagc agtactacca
     8821 gcctattatc caagttgcag cgagttgggg aagccttcag ttggccttta ctggagctga
     8881 acgaattcag gaaatgtttg atgcagagga ggaaatccga cctgaaaagg ctccaacctt
     8941 cactaagttg caagaaagtg ttgaaatcag tcatatcgat ttttcatact tgcctgataa
     9001 acctattttg aaagatgtca gcatttctgc ccctaaaggc cagatgacag cagttgttgg
     9061 gccgacaggt tcaggaaaaa cgactattat gaacctcatc aatcgctttt atgatgttga
     9121 tgctggtggt atttattttg atggtaaaga cattcgtggc tatgacttag atagtcttag
     9181 aagcaaggtg ggaattgtat tgcaagattc ggtcttgttt agcggaacga ttcgagacaa
     9241 tatccgattt ggtgtgccag atgctagtca ggaaatggtt gaggtagcag caaaagcaac
     9301 ccacattcac gactatatcg aaagtttgcc tgataagtac gatactctta ttgatgatga
     9361 ccagagcatc ttttcaacag ggcagaagca attgatttca atcgctcgaa ccctgatgac
     9421 agatccagaa gttctcattc tcgatgaagc aacttcaaac gtagatacgg tgacagaaag
     9481 caagattcag catgccatgg aggtggttgt agcaggtaga actagtttcg tcattgccca
     9541 ccgcttgaaa accattctca atgcagatca gattattgtc cttaaagatg gagaagtcat
     9601 tgaacgtggt aaccaccatg aacttttgaa gctaggtggc ttttattcag aactctatca
     9661 caatcaattt gttttcgaat aagaaagaag ttgtcctatg tgggcagctt tttcttgtcc
     9721 ataaaaaatg tttatcacag ccttaaaaaa aacatattag acgaaagtca ttttgagtga
     9781 tatgatagga ctatcgttag cattcgaaag gagaggcatc atggctagaa cggttgtagg
     9841 agttgctgca aatctatgtc ccgtagacgc agaaggcaaa atcattcatt catctgtatc
     9901 ttgtagattc gcagagatca ttcgtcaagt cggtggtctc cctttagtca ttcctgttgg
     9961 tgatgagtca gttgtacgtg attatgtgga aatgattgac aaactcattt tgacaggagg
    10021 ccaaaatgtt catcctcagt tttatggaga gaaaaagacc gtcgagagcg atgattacaa
    10081 tctggtccgt gacgaatttg aattggcact cttgaaggaa gcgcttcgtc agaataaacc
    10141 aattatggca atctgtcgcg gtgtccaact tgtcaatgtt gcctttggtg gaaccctcaa
    10201 tcaagaaatc gaaggtcact ggcaaggact acctttcggg acatctcact ctattgagac
    10261 agtagaagga agcgtggtgg ctaagctatt tgggaaagaa agtcaggtca actcagtcca
    10321 tcgtcaaagc attaaagatt tggcacctaa tttccgtgta actgctattg attcaagaga
    10381 ccaaactatt gaagcgattg agtctatcga cgagcaccgc attatcggtt tacagtggca
    10441 tccagagttt ctggttaatg aagaagatgg caatttagaa ttatttgagt atttattgga
    10501 tgaactgtaa caattggaac atctggtcgt tctttctttt attttttcaa aatttttaga
    10561 atgtggtatt ttacgcaaac gtttgaattc tgataaaaat tggagaaatt cgacaaaaaa
    10621 acttgaaaaa aacgaaggta agcgttatga tagaaaagaa gaaatattgg aggaagaaca
    10681 tgtcacatat taaatttgat tattcaaaag ttttagacaa atttgttgca ccacatgaag
    10741 tggaatacat gcaatcacaa gtaacagcag cagatgaatt gatccgtaaa ggaactggtg
    10801 ctggtagcga cttcttggga tggttggacc ttcctgaaaa atacgaccgc gaagaatttg
    10861 accgcatctt gaaagctgct gagcaaatca agtcagacag cgatgttttg gttgtgatcg
    10921 gtattggtgg atcttacctt ggtgcaaaag cagcaatcga cttcttgaat caccattttg
    10981 ctaacttgca aacaaaagaa gaacgcaaag ctccacaaat cctttacgca ggaaactcaa
    11041 tctcatctac ttaccttgct gacttggtag agtatgttgc agacaaagac ttctcagtaa
    11101 acgtaatttc taaatcaggt acaacaactg aaccagcgat tgctttccgt gtctttaaag
    11161 aactcttggt taagaaatac ggtcaagaag aagctaacaa acgtatctat gcaacaactg
    11221 accgccaaaa gggtgctgtt aaggttgaag cagacgctaa cggttgggga acatttgttg
    11281 ttccagatga tatcggtgga cgcttctcag tattgacagc cgttggtttg cttccaatcg
    11341 cagcatcagg agctgacata aaagctctta tggaaggtgc gaatgcagct cgcaaagact
    11401 acacttcaga caaaatctct gaaaacgaag cttaccaata cgcagctgtt cgtaacatcc
    11461 tttatcgtaa aggctatgca actgagatct tggtaaacta tgagccatca cttcaatact
    11521 tctcagaatg gtggaaacaa ttggctggtg aatcagaagg aaaagaccaa aaaggtatct
    11581 acccaacttc agccaacttc tcaactgact tgcactcact tggtcaattt atccaagaag
    11641 gaactcgtat catgtttgaa acagttgtcc gtgttgacaa acctcgtaaa aacgtgctta
    11701 ttcctacttt ggaagaagac cttgacggac ttggttacct tcaaggaaaa gacgttgact
    11761 ttgtaaacaa aaaagcaact gacggtgttc ttcttgccca cacagatggt gatgtaccaa
    11821 acatgtatgt gactcttcca gagcaagacg ctttcactct tggttacact atctacttct
    11881 tcgaattggc aattgccctt tcaggttact tgaatgctat caacccattt gaccaaccag
    11941 gtgttgaagc ttataaacgt aacatgtttg cccttcttgg aaaaccagga tttgaagaat
    12001 tgagcaaaga acttaacgca cgtctataat agaagaaaag agtggtttgc ccactctttt
    12061 tactctcttt atccatagaa attggactca gccaagactt gtgatataat atagaaagca
    12121 aaaaggcaga cgcctagata ataggagaaa ctatgtcaaa agatatccgc gtacgttacg
    12181 caccaagtcc aacaggacta ctacacatag gaaatgctcg tacagcattg tttaattact
    12241 tgtatgcgcg ccatcatggt ggaacatttc tcatccgtat cgaagatact gaccgtaaac
    12301 gccatgtcga ggatggtgaa cgttcacaac ttgaaaacct tcgctggtta ggcatggatt
    12361 gggatgaaag tccagaatca catgagaatt atcgccagtc tgagcgtttg gacttgtatc
    12421 aaaaatacat cgaccaacta ttagctgaag gaaaagccta caaatcttac gttacagaag
    12481 aagagttggc agctgaacgt gaacgtcaag aagtagctgg cgaaacacca cgctacatca
    12541 atgaatacct tggtatgagt gaagaagaaa aagcagctta catcgcagaa cgtgaagcag
    12601 cagggatcat cccaactgtt cgtttggctg tcaatgagtc aggtatctac aagtggcatg
    12661 atatggtcaa aggcgatatc gaatttgaag gtggcaatat cggtggtgac tgggttatcc
    12721 aaaagaaaga cggttaccca acttacaact ttgccgttgt tatcgatgac cacgatatgc
    12781 aaatctctca tgttatccgt ggagatgacc atattgctaa tacaccaaaa cagcttatgg
    12841 tctatgaagc tcttggttgg gaagctccag agttcggtca catgaccttg attatcaact
    12901 ctgagactgg taagaagtta tctaaacgtg atactaatac acttcaattt atcgaagatt
    12961 accgaaagaa aggttacctt ccagaagcag tctttaattt tattgctctt cttggttgga
    13021 acccaggtgg tgaagatgag attttctctc gtgaagaact cattaaactt tttgatgaaa
    13081 accgcctcag caagtcacca gcagcctttg atcagaaaaa actagactgg atgagcaatg
    13141 attatatcaa gaatgcagac cttgaaacca tctttgaaat ggcaaaacca ttcttagagg
    13201 aagcaggccg tttgactgac aaggctgaaa aattagttga gctctataaa ccacaaatga
    13261 aatcagtaga tgagattatc ccattgacag atcttttctt ctcagatttc ccagaattga
    13321 cagaagcaga gcgcgaagtc atgacgggtg aaacagttcc aacagttctt gaagcattca
    13381 aagcaaaact tgaagcgatg acagatgata aatttgtgac agaaaatatc ttcccacaaa
    13441 ttaaagcagt tcaaaaagaa acaggtatta aagggaaaaa tcttttcatg cctattcgta
    13501 tcgcagtttc aggcgaaatg catgggccag aattaccaga tacaattttc ttgcttggac
    13561 gtgaaaaatc aattcagcat atcgaaaaca tgctaaaaga aatctctaaa taaagaggat
    13621 acaataatgg acatctggga aaagatgtac gaagaagcac agaaactata caatccacat
    13681 gaagtatcag actttgttta tgccaatcat gttgtagctg cagtagaagc agaagatgga
    13741 caaatattta caggattctg tatggaggga acctgtggtg ttttccatct ctgcgcagaa
    13801 cgggcggccc tcttcaatac gtaccaattt tcaggacaaa ctaaggttaa gaaagtatta
    13861 gcctttcgag acaaaccacc ttatggtgga agttcagcca tgccttgcgg tgcttgtaga
    13921 gaattccttt tagagcttaa tgctgaaaat aaagatgcag aattcatgat ggactataat
    13981 ataagaaaaa cagttaaagt cgcagaacta atcccttatt ggtggggaga agaacgtgct
    14041 tctaagttta atgagcgata gaagagtcag tataattctg gcttttttta ctataagttg
    14101 aaaaaat
//
LOCUS       DAVBEM010000053        13538 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVBEM010000053 DAVBEM010000000
VERSION     DAVBEM010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13538
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.053"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(<1..1394)
                     /locus_tag="VQ548_001739"
     CDS             complement(<1..1394)
                     /locus_tag="VQ548_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec-dependent serine-rich glycoprotein
                     adhesin"
                     /protein_id="HET2654547.1"
                     /translation="MFKVMRGGVDTTQVMTETVEDKVSHSITGLDILKGIVAAGTVIS
                     GTVATQTKVFTNESAVLEKTVEKTDALATNDTVVLGTISTSNSASSTSLSASESASTS
                     ASESASTSASTSASTSASESASTSASTSISASSTVVGSQTAAATEATAKKVEEDRKKP
                     ASDYAASVTNVNLQSYAKRRKRSVDSIEQLLASIKAAVFSGNTIVNGAPAINASLNIA
                     KSETKVYTGTGLDSVYHVPIYYKLTVTNDGSKLTFTYTVTYVDPTTRALGNLSKMGHG
                     YSIYNTGTSIQTMLTLGSDLGTPSDVKNYITDKDGVLVRSYNTSTMTTWGSGYTWGNG
                     AQMNGFFAKQGYGLTSSWTVPITGTDTSFTFTPYAAKTDNIRTNYFKGRGKVVESSTT
                     SQSLSQSKSLSVSASQSASASASTSASESASTSASASASTSASASASTSASASASTSA
                     SASASTSASESAST"
     gene            complement(1392..1505)
                     /locus_tag="VQ548_001740"
                     /pseudo
     CDS             complement(1392..1505)
                     /locus_tag="VQ548_001740"
                     /inference="COORDINATES: protein motif:HMM:TIGR03715.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
     gene            complement(1743..2204)
                     /locus_tag="VQ548_001741"
     CDS             complement(1743..2204)
                     /locus_tag="VQ548_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2654548.1"
                     /translation="MGKERRKQGNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIA
                     ARFDCALPSVWAVLKQIKVILKKTTSFREQKPEKVSEFLDILDNLKDLPVLYIDETGI
                     NRYLYRPYAGAPRGEKVYDKISGRRFERTNEVEQKLNGSFLIRYIDSQIRE"
     gene            complement(2171..2314)
                     /locus_tag="VQ548_001742"
     CDS             complement(2171..2314)
                     /locus_tag="VQ548_001742"
                     /inference="COORDINATES: protein motif:HMM:NF013842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2654549.1"
                     /translation="MAYSTDFKQGALDSIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KGT"
     gene            2583..2963
                     /locus_tag="VQ548_001743"
     CDS             2583..2963
                     /locus_tag="VQ548_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2654550.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            3062..3283
                     /locus_tag="VQ548_001744"
     CDS             3062..3283
                     /locus_tag="VQ548_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET2654551.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            3300..3614
                     /gene="trxA"
                     /locus_tag="VQ548_001745"
     CDS             3300..3614
                     /gene="trxA"
                     /locus_tag="VQ548_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET2654552.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            3921..4454
                     /gene="queF"
                     /locus_tag="VQ548_001746"
     CDS             3921..4454
                     /gene="queF"
                     /locus_tag="VQ548_001746"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HET2654553.1"
                     /translation="MKHQSALVVFSGGQDSTTCLFWTMQHYETVEAVTFAYGQHHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(4708..5376)
                     /locus_tag="VQ548_001747"
     CDS             complement(4708..5376)
                     /locus_tag="VQ548_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HET2654554.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLSN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(5487..6041)
                     /locus_tag="VQ548_001748"
     CDS             complement(5487..6041)
                     /locus_tag="VQ548_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HET2654555.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRNVLLNQGL
                     HYLSKEKDTRGFSSQYGWVHAFAHGADLLTEVVCHPGFPKNRVHEVFEILGQLFKRMS
                     IRFTDDEDWRLARVIYEPILQGKLAQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDELKEAIQSFQY"
     gene            complement(6287..8083)
                     /gene="pepF"
                     /locus_tag="VQ548_001749"
     CDS             complement(6287..8083)
                     /gene="pepF"
                     /locus_tag="VQ548_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET2654556.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYGFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDATLTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKHSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIISYSAELGE"
     gene            complement(8094..8837)
                     /locus_tag="VQ548_001750"
     CDS             complement(8094..8837)
                     /locus_tag="VQ548_001750"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HET2654557.1"
                     /translation="MQQYFVKGSAVSPVTIEDRETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFITQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNVVPSIHLFENKADFLAQLDQ
                     FDRILVAYEEAAKEGEAAALIKAVTGLEKGAKLLFIFGPEGGLSPAEIENFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            complement(8839..9789)
                     /locus_tag="VQ548_001751"
     CDS             complement(8839..9789)
                     /locus_tag="VQ548_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HET2654558.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYMGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDMTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNTG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRQSAESAGFFLETHMIQGEWNACVFKKTKDISGVIGG"
     gene            complement(9927..10355)
                     /locus_tag="VQ548_001752"
     CDS             complement(9927..10355)
                     /locus_tag="VQ548_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2654559.1"
                     /translation="MELEISDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPGGG
                     REGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQFDN
                     IIFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            complement(10336..11424)
                     /locus_tag="VQ548_001753"
     CDS             complement(10336..11424)
                     /locus_tag="VQ548_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HET2654560.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            complement(11443..11913)
                     /locus_tag="VQ548_001754"
     CDS             complement(11443..11913)
                     /locus_tag="VQ548_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HET2654561.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     VLFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            complement(12204..12656)
                     /locus_tag="VQ548_001755"
     CDS             complement(12204..12656)
                     /locus_tag="VQ548_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HET2654562.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            complement(12693..12872)
                     /locus_tag="VQ548_001756"
     CDS             complement(12693..12872)
                     /locus_tag="VQ548_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HET2654563.1"
                     /translation="MPMTQKEMVKLFTAHGWIKTRGGKGSHIKIEKQGERPITILHGE
                     LNKYTERGIGKQAGL"
     gene            complement(13009..13188)
                     /locus_tag="VQ548_001757"
     CDS             complement(13009..13188)
                     /locus_tag="VQ548_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654564.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            complement(13353..>13538)
                     /locus_tag="VQ548_001758"
     CDS             complement(13353..>13538)
                     /locus_tag="VQ548_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654565.1"
                     /translation="IFTKQIRHWILSDQVISGKRKLFFREDTPKEILDLYENIKSKLD
                     FAYQEVHSNNGLKKYEK"
BASE COUNT         4026 a         3080 c         2465 g         3967 t
ORIGIN      
        1 ctcgttgatg cagattcaga cgctgaggta cttgctgaag ctgaggcact cgttgatgcg
       61 gaagctgacg cactcgttga tgctgaggct gaggcacttg tacttgctga ggctgatgcg
      121 ctggttgagg ccgattcaga agctgaggtg cttgctgagg ctgaggcgct ttgactagca
      181 cttactgaga gtgacttaga ctgtgaaagt gactgactgg tcgtgctaga ttcaactacc
      241 tttcctctac ccttgaagta gttagttcta atgttatctg ttttagcagc gtaaggggta
      301 aatgtaaagg atgtatccgt tccagtaatt ggtacagtcc aagatgatgt taatccatat
      361 ccttgcttag caaagaaacc attcatttgg gcaccatttc cccaagtata cccactaccc
      421 cacgtcgtca ttgtagatgt attataggat cgaaccagta caccatcttt gtcagtaatg
      481 tagttcttta catctgaagg ggtaccaaga tcactgccaa gggttaacat tgtttgtatt
      541 gaagtacctg tattatagat agaataccca tgacccatct ttgaaagatt accaagagcc
      601 cttgtggtag gatctacata cgtaaccgta taggtaaagg tcagttttga accatcattt
      661 gtcactgtca atttatagta aattggaaca tgatataccg aatctaaacc tgtacctgta
      721 taaacttttg tctcactttt agcaatgttt agacttgcat taattgcagg ggcgccattt
      781 acaatcgtat tgccagaaaa aacagcagct tttatagaag ccagcaattg ctcgatggaa
      841 tccactgaac gcttgcgtcg cttagcataa gattggagat tgacatttgt aactgatgct
      901 gcataatcac tagctggttt cttacgatct tcttcgacct tcttagcagt tgcttctgta
      961 gcggcagctg tttgtgatcc taccacagta gatgatgcag agatacttgt cgaagccgat
     1021 gtacttgctg attctgatgc acttgtactc gctgaggtcg aagcgctggt tgaggctgac
     1081 tcagatgcag atgtacttgc cgactctgaa gctgacaaac tagttgaact cgctgaatta
     1141 cttgtagata tcgtacctag aactactgta tcatttgttg ccaaagcatc cgttttctct
     1201 acagtttttt caagtactgc cgactcattt gtaaatacct tcgtttgagt tgcaacggtt
     1261 ccacttatga cagttcccgc agcaactatt cccttgagga tatcaagccc agtaattgaa
     1321 tgacttactt tatcttctac cgtttcggtc atgacctgag tagtatcaac accaccacgc
     1381 atgaccttaa acaagccaaa aagagaagtc gaggcccgta gccaatgctt ccctgatttg
     1441 attaatttga accgagttac tcggtctgtt tctctatatt cacccttctg acgtctaaaa
     1501 aatattttga aatttccttt cgagtattat tttcatgtat ggatataaat aaattaccat
     1561 actataatta tagaataggg aacccaaaat agcaagaaac ttgaggtatt tttgctaaaa
     1621 aaaaaaagca ttttactatt ttatatatat attataagat aagtttttta taaagacacg
     1681 caaatgagta taaatcagct aatttttggt ttatattcct atttttatgc ataattattc
     1741 tttcattctc taatttgtga atcaatatat ctgattagaa aactaccatt gagtttttgc
     1801 tccacctcat tagtccgctc aaaacgccgt ccgctaatct tgtcatagac tttctcccct
     1861 ctaggagccc ctgcataagg acgatagagg tagcggttga ttcccgtttc gtcaatatat
     1921 aggactggta aatcttttag gttatccaaa atatcaagaa actcagaaac tttctcaggc
     1981 ttttgttccc taaaactggt cgtctttttt aaaatgacct taatctgctt taaaactgcc
     2041 catacggagg gcaaagcaca atcaaaacgg gccgcaattt cccgtaaaaa agcgtctgga
     2101 tgagcctcta caaaggcttt caattcttct aaagggatct tacgcttttt gacgactcgc
     2161 tttttccgct ctaagttccc ttgtttacgt ctttcttttc ccacgtgaag agagttctga
     2221 cgccaacacc aaaaaacttg gctgcctcga catgactgtg cccctctttg atggaatcta
     2281 atgctccttg tttaaaatca gtactatatg ccatagcttt attagaccat gcttatttta
     2341 aactaagcaa ctatagatag agaaatgaaa taaaatctaa attcgaatgt gataaggagt
     2401 tagaaattga aacaatagga ttcccccatt attcacacaa aaataaaacc actaaaaaac
     2461 agagcttgcc agcattcttg aaaagtagta taattattgc atgcgcaatc atcttgtgac
     2521 gcagagactg cccgttaatg gactttcttc tatattatga ctctaaaaag aaaggagaca
     2581 ctatgaccta tttggaaaaa tggtttgact tcaatcggcg tcagaaagaa attgaaagtc
     2641 tcttggaaga gaccattgcc caacagagcg agcaaagtct gaccttgaaa gagttctacc
     2701 tgctctacta tctggacttg gctgaagaaa aatctctacg ccagattgac ctgccagata
     2761 aacttcatct gagcccgagc gcagtttcta ggatggtggc tcgcttggaa gctaaaaatt
     2821 gcggtctact cagtcgcatg tgttgccatc aagatagacg ctctagtttt atctgcctga
     2881 caaatgatgg gcaaaagaca ctggcctcgc tacaaaagac tgtcgaagaa agcttggaag
     2941 caggtttgga tttcttgatt taagatgatt ttaaaaaaag ttgcgtgcgc aatcattttt
     3001 cttgacattc tcttttataa ggagtaaaat aaagttagca ttaaacaaag gagttttaaa
     3061 tatgattgaa attacctata tagatgccag caagaacgaa agaactgtga ctttcgagtc
     3121 ttatgaagac tttgaacgtt cacaacaagc ttgccttatc ggcgtcgcag actactaccc
     3181 tgtccaaaaa ttaacttaca agggtcataa tttggactac catgggactt atggagatat
     3241 cttcttctat ctcatgaaac aagatttaag ccaatataac taaaaaaagg agaaatacaa
     3301 tggcaaaagc aattacagat gcaacattcg aacaagaaac aaaagacggt ttggtcttag
     3361 tagacttctg ggcaacttgg tgtggtccat gtcgtatgca aggtccaatc ttggacaaat
     3421 tgtctgaaga actttcagaa gatgtcttga aaatcgttaa aatggacgtt gatgaaaatc
     3481 caaacacagc tcgtgctttt ggaatcatgt ctattccaac tcttctcttc aaaaaagacg
     3541 gccaagttgt caaacaagtt gcaggtgttc acacagcaga acaaatcaag gccatcattg
     3601 ctgaattgag ctaatcaaac gagagaccaa gtactttctt tggtctcttt tttcttgccc
     3661 tttgccattt ttcaaaaaat atgctagact atagtagatt gaaactagaa tagtacacct
     3721 ctacttctaa aacattgtta aaaatcgatt tgactgtcct gatcgatttg tcctgttttt
     3781 atttcatttt actatataag tagaatatta cgatgtttgg gatatgccat cgctaaaaaa
     3841 aaactcgatt tggtattttt tagttcccta atgggagctt tttgcgtgct ctgaacattt
     3901 cccattttgg aaggagtact atgaaacatc aatcagcctt ggtcgtcttt agtggcggtc
     3961 aagattcaac aacctgcctt ttctggacca tgcaacacta tgaaacagtc gaagctgtca
     4021 cctttgccta cggccaacat catcacctcg aaattcaaat tactagagaa atcgctaagg
     4081 aacagggcat tcgtcaccat atcctcgata tgtctctgct gggacaaatc actgctcagc
     4141 cagactttgc gacgattcat atttcctaca ttcctgacaa gctctgtgtc gagtcaaaat
     4201 ccctcaaact atatctattt agctaccgaa accacggaga tttccacgaa aactgtatca
     4261 acaccatcgg gaaagacttg gtcaacttgc tagaccctcg ctatttagaa gtctggggaa
     4321 aattcactcc gcgcggtggc atttcaatcg acccctacta taactacggt aagcaaggaa
     4381 ctaagtatga gggcttggca gaacaacgcc tcttccaaca cgacctttat ccagagaaaa
     4441 ttgacaaccg ctaaagtcat actcaatgaa aatcaaagag caaactagga agttagccgc
     4501 aggttactca aagcagtgtt tgaggttgta gataaaactg acgaagtcag atcaaaacac
     4561 tgttttgagg ttgtggatag aactgacgta gtcagtaacc atacctacgg caaggtaaag
     4621 ctgacgtggt ttgaagagat tttcgaagag tatcatacga aaaagccctg ttcctcaaga
     4681 tgaggagcaa ggctttttga gtttcaatta ttcttctgtt ccaaggaaat tttttgcaac
     4741 aagggctgca agaactccac cagcgattgg tgcaaggatg aaaatccaaa cttgttgaag
     4801 ggctgcgccg cctaccaaga cagctggtgc caagctacga gctgggttta ctgaaagtcc
     4861 agtaatcttc aatccgacaa gaatcatcgc catcaatgac aaaccgatta ccaaaccagc
     4921 aatcgcgcca ttgcccttgc tttctgaagt cacagtcatg ataaccaata caaacaagaa
     4981 agttgcgatg acttcaaaca agaaaccacc aaagacagtg acaccgtttg ccaaggcatt
     5041 ttcaccaaga ctagcagttg acatacctga attactcaag aggaagaaga ctgcgccaga
     5101 agcgatgaaa gctccaacaa cctgaccaag gatgtagttt acaagttctg aagatgacaa
     5161 acgtttgttt acaaacatag caatcgaaac agccgggttc aagtgagcac ctgaaacagt
     5221 tccgattgag taggctgcca ccacgattgc caaaccaaag gcaaaggcga ttccaaggtg
     5281 accaaggcca tcaagaccat ttccaaaaac aacagctcct gttccaacga acacaagcat
     5341 gaacgtaccg attaactcag caacaaattt tttcattttc tttctccttt tttcaaaaac
     5401 tagatactag tctatcaaaa gtaggaaagg gtttcaagaa aattgattgg aaattttttg
     5461 aaaatcatag aactattagc taatctctag tattgaaaag actggatagc ttctttcaac
     5521 tcatcttgta aactatttct ctggtcaagt tggacataga cttccaccag acaggatcta
     5581 aagttggaaa atttgtaaaa atcctccctt tcttctatcg gaaaatcaac agtttttatc
     5641 caagaagcta cttgttcttg cgctaacttc ccttgtaaaa taggttcata gatcactctt
     5701 gctaaacgcc aatcctcatc atctgtaaag cgaatcgaca ttcttttaaa taattggcca
     5761 agtatctcaa atacttcatg aactctgttt ttaggaaagc ccggatgaca aaccacctct
     5821 gtcagtaaat cggctccatg tgcaaaagca tgaacccaac catactgact tgaaaaaccc
     5881 cttgtatcct tttcttttga aagatagtgc aagccttgat ttaaaaggac attacgaatt
     5941 tctggagaag gatttcccaa atgatcaaac aaccactgga tttcttcctg gttataattt
     6001 ggtttttctt ctgctatttt tcttagtaaa tcttgataca tggtcaatac ctctacattt
     6061 ctagcaactg ttcaaaaagg cagtcttaaa tgactcaata ttgaattctc aattaaatac
     6121 aatctgatat aaaatgacgt aaataactat caataccagt tctacagtaa gttcaaattt
     6181 aacatcacga tcttcaacga catttttgaa aatagctaca actaagacaa atagaatgac
     6241 gcttaacaag cccataaaca tcattctaaa aaatttttct attcccctac tctcccaact
     6301 cagcactata ggagataatc tggtcaactg tgtcagacaa gaattggatg gtatcacgga
     6361 gtggtttgtc tgttgaaata tcagcaccga taatcatggc tgactcaagt ggtgtcttgc
     6421 taccacctga tttgaggaga ttgagccagt cttcagctcc agtttcagaa tgttttagat
     6481 gaaggtaacc agcagtcgag ataactagtc ctgctgagta agtgtaacta tacaagccca
     6541 tatagtagtg agcttggcgc atccaagtca gagttgcatc atcgtcaatt tcaatagcat
     6601 ctccccagaa atccgtcaaa acttccttca taatgctgtt gagcttgctt gctccaaagg
     6661 tctccccttc ttcaatcaat gtatacacct tacgctggaa ggcggcttcc aagaggtggg
     6721 tgataaagtt atggaagtag gtgtctgtca agcgatgagc cagagcgaag cgtttttgac
     6781 gtgggtcatt agactggttc tccaagtaat cactgagtag caattcattg aaggttgacg
     6841 gtgcttcaac atagtaggtc gacatatggg cattgaagta actttgatga ttgtctgaaa
     6901 agatgaattg accagaatgc ccgatttcat gaatcaaggt atagacatcg ctcaaacggc
     6961 ctgtccagct catgagtaca taagggtgta cgcgatatgg gtccgccgca taaccaccgg
     7021 aatccttgcc actgttagca gcaaagtcca cccagcgctc ttcttggtaa cgagcaactt
     7081 cctgacaata ttcttgcccc aaaggttcta ccgacttcat gaccaaatca taggcatcgt
     7141 caatagtcac ttcaggattc agggcgctgt ccaagtccaa tttccagtct gcaaaggtca
     7201 tcttttcaag accatttacc ttggcaacat gcttgaggta tctctgagcg actggtgcaa
     7261 agtccttcat gatgaggtca atctggcggt caaacatgac acggtccact tcttgttcag
     7321 ctagaagata gtcaaagaca gagtcgtatc ccttcatatc agccaagagt ttttcagact
     7381 tgacctgagc cagataggct gctgcagccg tattttggtg cttacgaagt ccctctgaga
     7441 aggaacggaa ggatttctca cgaacctcag catcctcatg gttttggtag aaattctcat
     7501 aggtcacaaa gctgtttttg taggtcttgc catgggcttc aaagtcagcc atttcaaaat
     7561 ccccagctcg catcttagta taaatgtcct gcggactgta gaaaacttca ccgagatttg
     7621 tcaaggcctt ctccacatct gcccctaagt agtgggcttt tttgatttta gcctgacgaa
     7681 tggcagctgt taaatgtggc aatttaccca aacgatccaa gacttcctcg tctgctgcca
     7741 ccaaggcatc gtcaaaaaag gtcaaggcta cgctggcatc tgtttcaaat tccatcccag
     7801 cttgagcaat atttgcaaat tcgtcattgc tatagtccgt cgtctgaggc ataaaaccat
     7861 agttgccaat atggctcatc tgaatgtaga tctgttccaa ttccgcaaag gccttctcga
     7921 aatcctcaaa agtgtgaaga ttgcccttgt aatcacggct aaactggttg atgtcttcgc
     7981 gagctttctc gattgcacgc aagaaatcct cacggtcttg gtatagagct gttaaatccc
     8041 aaagttcctt ctctggaaat tctgaacggt gtttttgttc cattttcttc ctcttatttc
     8101 tctaattcta ctaaaacact aagggctgat aaggcgtaaa gcggtgctgt ttctgctctt
     8161 agaatgcgag ggccaagtcc tgccaaaaca gctcccttag cttcaaaatt ttcaatttcc
     8221 gcaggtgaca gaccaccttc tggaccaaag ataaagagca atttggctcc tttctcgagt
     8281 ccagtaactg cttttataag agcagcggct tctccttctt tggccgcctc ttcataggct
     8341 actaagatgc ggtcaaactg gtcaagttgg gctagaaagt ctgctttatt ctcgaaaaga
     8401 tggatacttg gaacaacatt acgcttactt tgctctgctg ctccaagagc aattttttct
     8461 agtttttcaa cctttttacc caatttcttg ccatcccact tagcaacgga ccaatcggca
     8521 gggaaggccc aaatctggct ggcacctagt tccgtcacct tttgagtgat aaactccaac
     8581 ttatctccct tgggaaatcc agatgcgatg gtcacttgga ctggtagttc cacattgtca
     8641 tttaattctt ggaccaactc aaactgacga ttttccatat ccagcacgcg cgccaagcgc
     8701 ttgatgccat catcaaagac taaggtaacc tcatcctctt ctttcaagcg cataacctga
     8761 aacatatgct tgctggtttc cctgtcctcg atggtgacag gagagactgc actccccttg
     8821 acaaaatact gttgcatgct agcctccaat cacacctgaa atatccttgg tcttcttgaa
     8881 gacgcaggca ttccattccc cttgaatcat atgggtttca aggaaaaatc cagctgactc
     8941 agccgactgg cgcaccatgt cccacttgtc cttgataatg ccactcatga tgaggtagcc
     9001 ttcatccttt accaagcgat aagcatcctc cgtcagatga atgagaatat ccgccaagat
     9061 attagccacg atgacatctg cttcaatctc aactccctta agcaagtctc ctgctgctac
     9121 atggatattt tccataccag tgttgagctc aatattttcc tgagcgacac gaaccgccac
     9181 atcatccaag tcataggcga aaatctcctt ggcacctagg agtgagcttg caatagaaag
     9241 aacccctgaa ccagtcccca catctagcac cgtttcgcca ccacgaagaa cctgttccaa
     9301 ggcaaaaagg ctcatcttgg tagttgggtg ggttccagta ccaaaagcca tgccaggatc
     9361 cagcttgata attttttctc ccgcagtcgc ctcatagtct gtccaagagg gaacgatggt
     9421 caaatcatga gtgatgcgag caggttcata gtatttcttc cagttgtctg cccagtcttc
     9481 ctcagccaag gcagtcgtac ctatttttaa ctctcccaaa tccataaaat ccgtcaattc
     9541 tgctaagcga gcctgcaagt ccgcctcaac cactgtcata tccaccgtgt cagggtagta
     9601 ggctgtcact acgatttctt cttgctgctc cacctctggg aaaatctcgc caaaacgatc
     9661 cacatttccc atatagtcca tgctgtcttc aatcgcgact ccttgcgctc ccagctcaat
     9721 caagagattg gaaaccaact cctctccctc acgcttcact gtaactttta actcttgcca
     9781 tgtttccatt attaagatac caagcccgta aaacacaaaa ccaaaatagg aaattctctg
     9841 aagacgcttg tgtctaagag aagtttatct ttttggcaca gtgtttaggg cgggttcagt
     9901 ttagaaatgt aactgaacca tcctttctaa tcacttactt ttaaataatc ttttaatctc
     9961 tcttgcaact gaggcacaac ttgactggaa ctaagaaatt cctcaacatt catcagctga
    10021 tagccctgtc cttcatctcc gaagatgata ttgtcaaatt gttcttgtct tagctgacca
    10081 accataaaga ccgatttctt gcctttaaaa attacgctag gataaatctt gctccaaagc
    10141 agacagtctt catctaaatg aattcccagt tcctcataaa cttcacgccg agcgcattca
    10201 aaagggcttt cgtccccttc acggccacca cctggcaact cccacatgtt gggacaaggg
    10261 atatcgtcct tgtcatcacg caaaatcgtc agtagcttat ccccacaaaa gagggcaatc
    10321 ttgcaacctt ggaaatcaga aatttctagt tccatcttca gttccttcta acatttcctt
    10381 ttccagctct gctaacaagt tttcataata gcgtttctcg tccctcaaca ttcgactact
    10441 atccattttc tgtctagcaa tcttgagagc cttacgagtt cgatctacat ctttcttcac
    10501 ctttaattga taccaggctt gtatcacttg aagattggac agtttgagag acagaaacga
    10561 tttgacctgt cgaatactag catattgctc cgcttgctca aaatctcctt ccaacaaggc
    10621 gatatgaagc agggatagtt gggcaactgt ctgcatcatc ggagtagttg tcctctcaag
    10681 taatgcttga aactgctgtt tagctacttc ttccttccct tccaaaatgg aaacttcacc
    10741 ttgcatacct aatacaccat ccgcaaaact ccctcgtgca tcctcaggaa ctgcttgaac
    10801 aaagtctttc aaatcatatt cttgaggagc cagcaaagtt tgagcagaat gtctcaatac
    10861 caggtaggcg tatttggtat tttcagggtg ttgtagtaat tcccaaattt ttgctccatc
    10921 ggtgatgtcg actggcaaaa tgttatttag gaagaaagat aaattaagaa aaatccaagt
    10981 ccctgcaaaa taccagcttc ttgtcaaaaa tccaaacact atcgccaata atatcaagcc
    11041 gagatgaacc atcaagcctc ctgaaagcat caggatgatt ctttgatcgc tttcatcctc
    11101 ttttaaacca atgtattgag caccaacatt tttcagaatg gctgttctac taagatgaaa
    11161 cctgcctgac tttttggtca aaataaaatg tcctaatcca aaagccacca gccgatagcc
    11221 tgtcaagtag ccacaaaaag catgacccag ctcatgaaga ataaagatta aatacatgct
    11281 tagaagagcg aaggcataac caaaagtaaa ggctaaaact gcggaatacc ccaactctgc
    11341 aaatgcgatt gttccacaag caaaagctag cataataaag acaacagcta gcacataaac
    11401 caaataagtc ccaattttct tcataacacc tccaaccaac tcctagtatc ttggataagg
    11461 ataaaattct ccctcttcca agccaacttt tccttcttca aagacttctt ggttccattc
    11521 catgacaaat tcctctgctt ctgggtcttc caaaaagtcc atgaggacat ctagcccaac
    11581 ctcagcagta tctttaagga aaagcacaaa ataagctaaa aattcacggg aaaatccttt
    11641 tttaggcagg taaggaataa cagtcaaata gtcttcctca ttgactgttg acttagcagg
    11701 attgtagaaa aggaccgctt cctcaaaaag aatgtcatct gatgaaacct ctccgtcttc
    11761 atccaccatc tccacacctg cagcattttg cgcttccaat agaaaactca cttctaccgc
    11821 atggttgcgt ttgtcccagc taatctcaaa gtcaaaggga aagttcttgt ccaactcttc
    11881 ctctaaaaca tctaaaaatc cgtatgttgc cattttgtcc tctttctatg cgactcttta
    11941 atcgccccga ttgctcggaa atatgctaaa atagatacta ccatcttacc acaaaattat
    12001 tttatgtcct aattatacca tattacctca tttaaaccct tggtatcagt gattttctta
    12061 aaagtctgat ttcttcattt ctcataaaaa tcaatataaa aagccctcga aagggctaat
    12121 aaatctataa aatcaatagg cgagtaacta gcacaagtgg acgtgctttt ttattgacta
    12181 ttaccacgat accacgctta atcttaggct tgaactttct tatctgcaat agcgtctgtc
    12241 aaagtctgag aaaagttaag tcccatttct cgtcccaact tatctgccca ttttggtatg
    12301 gtcaaagtct ttttaatggg ttcctgactt cctaggtatt ctgatacatc aacagatacc
    12361 atagaaataa aagatttatc aaggtcatag gttgacacga aatcttcatc atctttaaaa
    12421 ggatcattat caattaaaga caagctattg atatctgatg gctgaggtaa ctctccatca
    12481 ctctctatca aatctgcaac agttatccct agccactccg accccatagc caaagcctca
    12541 gaaatcccct ctccttgtgt agctgagtat tcaaaatctg ggaaatggac aaaataagtc
    12601 gcttctgttc cgtctgtgtc gtcataataa aataaagctg gatacgtaac taacatttca
    12661 ctacctccat atcaaaaagc agggactgaa ttttacaacc cagcttgctt tcctatccct
    12721 ctttcagtgt acttattcag ctcaccatga aggattgtga taggtctttc cccttgcttc
    12781 tcgattttaa tatgggagcc tttaccgcct ctagtcttta tccaaccatg ggccgtaaag
    12841 agtttaacca tctctttttg tgtcataggc atagcgcttt tacctcctga caacaccatt
    12901 ataacacgtg ttacacgtat tgtaaaggag tgatacttat tattctatta tacataaaag
    12961 cccctagatg tggttctaag ggaaaccaat ttattcagac ctatttttct aatgagtagt
    13021 aaaaactgct tctttatcga gcaattcatc atctgtatag tcaattgtaa aagtatctcg
    13081 atctaagaca gattgaggcg gagttgaatg aatcatagga ccactgcgta ctctatattt
    13141 tttatctcca atttttacaa actgatactc ttcgaaaatc aaattcaaac cacgtcaacg
    13201 tcgccttacc gtactcaagt acagcctgcg gctagtttcc tagtttgctc tttgattttc
    13261 attgagtatg attaactctc aagtcttcga aatcaggatt ttcaacagtt attacaagga
    13321 ggcgatttac tacttcaaaa acatcaatta ttctattttt catatttttt caacccatta
    13381 ttagaatgaa cttcttggta agcaaaatca agtttagatt taatgttttc gtacaaatct
    13441 aaaatctctt ttggagtatc ttcccggaag aaaagttttc ttttccctga aataacttga
    13501 tcactaagaa tccaatgacg aatttgtttt gtaaaaat
//
LOCUS       DAVBEM010000054        12635 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVBEM010000054 DAVBEM010000000
VERSION     DAVBEM010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12635
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.054"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(313..495)
                     /locus_tag="VQ548_001759"
     CDS             complement(313..495)
                     /locus_tag="VQ548_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654566.1"
                     /translation="MAVIFKNVLIEEKTEEEKQHILSILNGEYDLSDDVSCRLRRLNE
                     ESKRLEVFVKETNSLV"
     gene            complement(711..1943)
                     /locus_tag="VQ548_001760"
     CDS             complement(711..1943)
                     /locus_tag="VQ548_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET2654567.1"
                     /translation="MKIAVAGTGYVGLSIAILLAQHHQVVAVDIIPEKVELINKKKSP
                     IQDDYIEKYLAEKELNLVATLNAEEAYENADFIVIAAPTNYDPKKNFFDTSSVEAVIE
                     AVMKYNPDAIIIIKSTVPVGYTKSVRRKFLTDNIMFSPEFLRESKALYDNLYPSRIII
                     GTDKDDKDLVKSAEIFVKMLQEGAVKENIETLYMDFTEAEAVKLFANTYLALRVSYFN
                     ELDTYSEMKGLDTQAIIDGVCLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYSDVPQ
                     EMITAIVQSNRTRKDYIADRILDLAGSYVGNDFYKPDKEKEIVVGIYRLTMKSNSDNF
                     RQSSIQGIMKRLKAKGVTIIIYEPTLESGTTFYGSQVVNDFEIFKKSSQVIVANRFDE
                     TLEDVRGKVYTRDIFKRD"
     gene            complement(1972..3042)
                     /gene="gla"
                     /locus_tag="VQ548_001761"
     CDS             complement(1972..3042)
                     /gene="gla"
                     /locus_tag="VQ548_001761"
                     /EC_number="5.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001214397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucuronate 4-epimerase Gla"
                     /protein_id="HET2654568.1"
                     /translation="MRGKTILITGVAGFIGSNLVRKLLELEGTMTIIGLDNLNDYYDI
                     ALKDYRLLQLNKLIQDYPEKNWIFIKGDIADKMLINKIFKSYHPQIVVNLAAQAGVRY
                     SITNPDVYIESNIVGFHNVLEACRHSYEIYDGGVEHLVYASSSSVYGGNKKIPFATED
                     KVDNPISLYAATKKTNELQAYAYSKIYNIPSTGLRFFTVYGPAGRPDMAYFGFTDKLR
                     SGSDIEIYNHGNCKRDFTYIDDIVEGIVRVMQSAPKKLVGSDNLPLAPYKVYNIGNSK
                     PENLLDFVDVLQQELIKAGVLPENYDFDSHKKLVPMQPGDVPVTYADTSDLERDFGFK
                     PKTSLREGLRKFAEWYKDYYNV"
     gene            complement(3110..4279)
                     /locus_tag="VQ548_001762"
     CDS             complement(3110..4279)
                     /locus_tag="VQ548_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HET2654569.1"
                     /translation="MRLSKKYWFALTSKFLLILLTLLSSIIINRGLGVEKKGDYAYVM
                     NLVEIFYILGGVGLGQAYSTFKRNHSNEYQNKFVFLTFIQGLLFGIIGLIIVLADVPI
                     DYGGVIIVLSSLSIMRTNLTMIAVIENSIKRNKIVLGVSVVYSVMLVLLLLFHLVSIE
                     MVFLVYAINEFLRIILFLYYYNMFPVFEHISIKEFFTIYKFGFLSMILTLLITFNYSI
                     DIIMLKQMSSSYNVGIYSVAVTFSNMFLMVPDSFKEILFGDSAKRTFEKNKAINAIKV
                     SFLFMILLIIGFLSFGEFAITLLYGSSYIKAFPITLVIFLGSLSMIFFKILQPIYISQ
                     GKQSVAIKILSVSALINISLNWYLIPNYQITGAAIASAISYTVCGLFFIIDYLRN"
     gene            complement(4465..5769)
                     /locus_tag="VQ548_001763"
     CDS             complement(4465..5769)
                     /locus_tag="VQ548_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HET2654570.1"
                     /translation="MKFSLQSNDIKNKIILLVGVVFSGTLILCSENNDVTIPLFSMIF
                     LSFMAMIIVKFNIFHPYVWYSSFFTIYSISYPLLYRMEYINYGYTKDLIFMQWLALAT
                     LLLTLPSKAIVLSERKINLNNNNYLLFLNNMNTFITTVAIIYLLGSGFRNKGEIYSGA
                     NIVIMLVFSLVYFMILIHTYQLFIQLSTKKWRLLNCNTNTAIVICLFSIVTGERDYMF
                     TLFILDVIILFYFHKIKRFYLVMLVPLAALLIPLSAVFKYTLLSGQVSSINTNNIWFD
                     LLDGEFVSASRNLQILILHNMGNYFEGRSFFNDIVRIFYNTGYSNQTWFMDTFFPNVH
                     STKYGFTLVGEGYVNGGYFGIVMIFMLTGFLMRFLYINAQRNIYGMLIYLYMIPIFIY
                     STRADFANILSPLLKYAILGTLVIVFINRMVLISPLDEMGGE"
     gene            complement(5886..7040)
                     /locus_tag="VQ548_001764"
     CDS             complement(5886..7040)
                     /locus_tag="VQ548_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2654571.1"
                     /translation="MKVFIATEFRCTIYKNEIYLKPKAYFIYERYAKAFGEIVLCSRY
                     EKVESYPEGYHKANFINKFIPIEGLHQVLFGQNKNKIIEGMIDSDLIVVRIPSIIGSK
                     TADYALKIGKPYLTEIMGDAWDSYWYHSLKGKLLAPYIYAKTKSIVKNANYCIYVTEK
                     YLQDRYPNIKSNIVASNVNITSVENRSLKSRLYKLKKFNPQKISIMTTASVNVRAKGH
                     RFVLEAMKRLEIQGILLDYYLAGDGDQSFLKKKAEELGVANRIHFLGELTTSQIYEYL
                     DKVDLYIQPSLQEGLPRAVIEAMSRACPCIGSNKAGIPELLGPHCLFTPSSSQAIAGS
                     IIDFISMDKEKMVIKQFEFSKKFLSSVLNKRRSDYFAQIRRELNNSDGLD"
     gene            complement(7037..7588)
                     /locus_tag="VQ548_001765"
     CDS             complement(7037..7588)
                     /locus_tag="VQ548_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HET2654572.1"
                     /translation="MNRIIKNIVGLLRANICLILLKVCRNKDLTFHYFLKFGKNVTVE
                     QESNAKLILGKKIRVNAGGVLKVRKGAKLKISDDVFLSNNCMIACRKYIDIKSGVKCG
                     PGVLIYDHDYDVSVPGGLKAKKFKTAPVMIGENVWIGANSIVLKGVSIGENSVVAAGS
                     VVTKDIPADTIFIQKRLSREMKL"
     gene            complement(7581..8717)
                     /locus_tag="VQ548_001766"
     CDS             complement(7581..8717)
                     /locus_tag="VQ548_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001053205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2654573.1"
                     /translation="MNLQKKKIMLITNHDDDIYCFRKEVIESLVEYGYEVLVSCPYGD
                     KIELMKSIQFEYEDITIDRRGINPLKDIRLFLSYIRLLRKYRPDVVLTYTVKPNVYAS
                     LAATILGIKYINNVTGLGSVLTMGSCVRSLVLLLFRISFRKSNCVFFQNEYNMKMLKT
                     LGLILGDSKLIPGSGVNIEKYPVQQYPNGGNGIQGETIVFNFIGRILKEKGIDTYLAA
                     AQIIKSRYPKTEFNIIGFIEPTESNYELKICDLEKKGIVYYLGQQKDVIPHITRSHAI
                     IHPSVYGEGMSNVLLENASSGRVLITTDNPGCKEIVKDRETGYIFQGGNVEELVSILE
                     VFLGLENEKRKEMGLQGRMYIEQYFSRQIIIDAYLDKIKGALDE"
     gene            complement(8858..9523)
                     /gene="cpsD"
                     /locus_tag="VQ548_001767"
     CDS             complement(8858..9523)
                     /gene="cpsD"
                     /locus_tag="VQ548_001767"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HET2654574.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNTLCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIAMSFARAGYKTLLFDGDIRNSVMSGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMFETLRKYFDYIIVDTPPIGIVI
                     DAAIITQKCDASILITATGEANKRDVQKAKQQLEQTGELFLGVVLNKLDISVDKYGVY
                     GRK"
     gene            complement(9533..10225)
                     /gene="cpsC"
                     /locus_tag="VQ548_001768"
     CDS             complement(9533..10225)
                     /gene="cpsC"
                     /locus_tag="VQ548_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HET2654575.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYLVNRNQGEKPGLTNQDLQAGAYLVKDYREIVLSQDVLEEVISDLKLD
                     LMPKGLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGVIGTSVIVLLLELLDTRVKRPEDIENALQMT
                     LLGVVPNLGKLK"
     gene            complement(10234..10965)
                     /locus_tag="VQ548_001769"
     CDS             complement(10234..10965)
                     /locus_tag="VQ548_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase CpsB"
                     /protein_id="HET2654576.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     gene            complement(10967..12412)
                     /locus_tag="VQ548_001770"
     CDS             complement(10967..12412)
                     /locus_tag="VQ548_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET2654577.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLICFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSKIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADS
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLTDGDRDRGRNQQKVIVAIIQKLTST
                     EVLKNYSSILQGLQDSLQTNIPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLTVVKAAIQDVMEGR"
BASE COUNT         4257 a         2449 c         1666 g         4263 t
ORIGIN      
        1 gaaatttgtc ctttctcgag cttagctgac ttcaacccac tacagttgac aaagagccta
       61 aaaattcact tacttcatat tacatttagc atgaaatgaa ataagcgaat tctactttgt
      121 ttgcatacaa ttaaaaatca attcctaagg atgttttaaa taactgtgta aaaggcataa
      181 tttcaccatt tcttagtttt tcaatgctaa attacatagt aactggagag ctattagaaa
      241 tctctaactt cctcatagtt aaaaaatgac aatgagatac ttattgattt caattcatta
      301 acagaatacg aactagacaa gtgagttcgt ctccttaaca aacacttcca agcgtttact
      361 ttcctcattc agtcgtcgta atctacaact tacatcatca gataagtcat actcaccatt
      421 tagaatagat agaatatgtt gtttttcttc ttcagtcttc tcttcaataa gcacattttt
      481 aaaaattact gccattatca gcacctcact tcgaaggaat atatgcaact atatcctatt
      541 aagtcaatct ctactgacaa aagaagtata tttacttcac taagtgcgag cgagaatata
      601 gaaatatctt tattgtttta gatgagttgt cgctatcctc cagctagttt ttaactattc
      661 tatcattcaa atgatataga ttattaggga ctagaaatat acaaattgat ttaatctctc
      721 ttaaaaatat ccctagtata aactttaccc ctcacatctt ctaaagtctc atcaaaacga
      781 tttgcaacaa tcacttgact agatttctta aatatttcaa aatcattaac tacttgacta
      841 ccatagaaag tagtaccact ttcaagagtt ggttcgtaaa taataatagt aacacctttt
      901 gctttcaaac gcttcataat accttgaata gaagattgtc taaaattatc tgaattactt
      961 ttcattgtta aacgataaat tcctacaaca atctcttttt ctttatctgg tttatagaaa
     1021 tcattgccta cataagatcc agcaagatct aaaatacgat ctgcaatata atcttttctt
     1081 gtccgattac tttgtactat agctgttatc atttcttgtg gaacgtcaga ataatttgca
     1141 agaagttgct tggtatcttt aggaagacag taacccccat aaccaaaaga aggattattg
     1201 tagtgagaac ctattctcgg atctaaacaa actccatcaa taatcgcttg agtatctagt
     1261 cctttcatct cagaataagt atctaactcg ttaaaatagg aaacccggag ggcaagatag
     1321 gtattagcaa aaagttttac tgcttcagct tctgtaaaat ccatatacaa tgtttcaata
     1381 ttttctttca ctgcaccttc ctgaagcatt tttacaaaaa tttcagcaga ctttaccaaa
     1441 tctttatcat ctttatctgt acctataata attcgactcg gatataggtt atcatataac
     1501 gcttttgact cccgtaaaaa ctcaggacta aacataatat tgtctgtaag aaatttcctc
     1561 cgtactgact ttgtatatcc aacaggaaca gtacttttaa ttattataat tgcatcagga
     1621 ttatatttca taactgcttc aatgacagcc tcgactgaag atgtatcgaa aaaatttttt
     1681 ttcggatcat aattagttgg agccgcaata actataaaat ccgcattctc atatgcttcc
     1741 tctgcattca atgtagctac gagattcaat tctttttccg cgagatattt ttctatataa
     1801 tcgtcttgga taggggactt ctttttattg attaactcaa ctttctcagg aatgatatct
     1861 acggcaacaa cttgatgatg ttgagccagt aagattgcaa tagataatcc aacatatcct
     1921 gtacctgcta ctgctatttt cataattttt tcctttctca aaacactctc gttatacatt
     1981 atagtagtct ttataccact ctgcaaactt tctcaaacct tctcgtaaag aagtttttgg
     2041 tttaaaacca aaatctctct ctaaatcact tgtatctgca taagtaacag gaacatcgcc
     2101 tggttgcata ggaactaatt ttttatgact atcaaaatca taattttccg gcaaaactcc
     2161 tgccttgatt agctcctgtt gaagaacatc cacaaaatct aacaaatttt cgggtttact
     2221 attcccaata ttgtacactt tatatggggc taacggtaaa ttatcagatc ccactagttt
     2281 cttcggagct gattgcatga cccttactat cccctcaacg atatcatcta tataagtaaa
     2341 atctcgttta caattaccat gattataaat ctcaatatcg gaaccacttc gcaatttatc
     2401 tgtaaatcca aaataggcca tatctgggcg cccagcagga ccataaactg taaaaaagcg
     2461 taagcctgtc gaaggaatat tgtaaatctt tgaataagca tacgcttgaa gttcatttgt
     2521 ttttttagtc gcagcatata gtgaaatagg attgtctacc ttatcttctg ttgcaaacgg
     2581 gattttttta tttccaccat ataccgatga ggacgatgca taaactaagt gttccacacc
     2641 accatcatat atctcatacg aatgacgaca agcttccaac acattatgaa agccaacgat
     2701 attactttct atatatacat ctggatttgt aatggagtag cgtactcctg cctgggcagc
     2761 tagattaaca acaatctgag gatgataact cttaaaaatc ttattaataa gcattttatc
     2821 tgcaatatca cccttgataa atatccagtt tttttctgga taatcctgaa ttagcttatt
     2881 aagttgaagc aatcgataat ctttaagtgc aatatcatag taatcattca aattgtccaa
     2941 accaatgatt gtcatcgttc cttctaattc caataatttc ctaaccagat ttgatccaat
     3001 aaaaccagct actcctgtaa ttagaattgt ttttcctctc atatcataat acctcttgtt
     3061 atttttatat tttcgtccac taatacacat tctttaacaa ctattataat caatttctaa
     3121 gataatctat aataaaaaac aaaccacata cagtataaga gattgctgat gctatcgcag
     3181 ctcctgtaat ttggtagtta ggaattaagt accagtttaa acttatattt atcaaagccg
     3241 acacagataa aatttttata gctacactct gtttaccctg agatatataa attggttgta
     3301 aaattttaaa gaaaatcatc gataagcttc ctaaaaaaat gactaatgtt ataggaaatg
     3361 cctttatata actggaacca taaaggagcg taatcgcaaa ttctccaaaa gaaagaaatc
     3421 caataattaa taaaatcata aatagaaatg atacttttat tgcatttatt gctttatttt
     3481 tctcaaaagt tcttttagcc gaatcaccaa ataaaatctc tttaaatgag tctggaacca
     3541 tcaaaaacat attagaaaac gtaactgcga cactgtatat acctacatta taactactag
     3601 acatttgctt caacattatg atatcaatac tataattaaa tgtaattaat agagtaagaa
     3661 tcatagaaag aaatccaaac ttatatatag tgaaaaattc tttaatacta atatgttcaa
     3721 aaactgggaa catattgtaa tagtataaaa ataaaatgat acgtaaaaat tcattaatag
     3781 catataccaa aaataccatc tctatagaaa ctaaatgaaa tagtaacaac aatactagca
     3841 taacggaata tactacgctt actcctaata caatcttatt cctctttata ctattttcta
     3901 ttactgcaat catagtaaga tttgttctca taatagatag actggacaaa actattatta
     3961 ccccaccata atctatcgga acatcagcta aaactattat taaacctatt attccaaaca
     4021 ataatccttg aataaaagtt aaaaaaacaa atttattctg atactcatta gaatgattcc
     4081 ttttaaaggt cgagtaagcc tgacctaaac caactccacc taaaatataa aaaatttcta
     4141 ctaagttcat tacataggca taatctcctt ttttttcaac acctaatccc ctattaatta
     4201 taattgagga taaaagtgtt aataagatta acaaaaattt actcgttaaa gcaaaccaat
     4261 atttcttaga tagtctcact tattttctcc gtatgttaaa ttttataaca gtaaatttaa
     4321 aattatagta tattgaaata gaatatgaac aaaacgatta gggaatttaa agtaatttat
     4381 aaaaattctt tagaagctgc attgtactac tccaacttca aaccactata gtatcaaaaa
     4441 gtatacccca cctttttaaa taaactactc accacccatt tcatccaatg gtgatatcaa
     4501 caccattcta ttgataaaaa caataaccaa tgttcccaat atagcatatt taagtaatgg
     4561 agataatatg ttagcaaaat cagcacgagt agaataaata aaaataggta tcatatacag
     4621 atatatcagc atcccgtata tatttctttg agcgtttata taaagaaatc tcatcaaaaa
     4681 gcctgttagc ataaaaatca ttacaattcc aaagtatcct ccattcacat atccctctcc
     4741 cacaagagta aaaccatatt tggttgaatg tacgtttgga aaaaaggtgt ccataaacca
     4801 agtttgatta gaataccccg tattataaaa aattcttact atgtcattaa aaaaagaacg
     4861 accttcgaaa taattgccca tattatgtaa tatcagaatc tgtaaattac gactagctga
     4921 tacaaactca ccatctagca aatcaaacca aatattattt gtatttatag atgaaacttg
     4981 cccacttaat aaagtatatt taaaaactgc agataacgga atcagtagtg ccgcaagcgg
     5041 aactaacatt acaagataaa aacgttttat tttgtgaaag taaaataata taatcacatc
     5101 aaggatgaat aaagtaaaca tataatctct ttcccctgta acgatagaga agagacagat
     5161 aactatcgct gtgttagtat tacaatttag tagtctccat tttttagtac tcaactgtat
     5221 aaatagctga tatgtatgaa tgagaatcat aaaataaacc aaagaaaata ctaacattat
     5281 cacaatattg gcacctgaat atatttcccc tttatttcta aaaccacttc ctaatagata
     5341 tataattgct actgttgtga taaacgtatt catattattg agaaataata aatagttatt
     5401 gttatttagg tttattttcc tttcgcttaa cacaatggct ttagaaggta gagttaacaa
     5461 caaagttgcc aaagccagcc attgcatgaa aatcaaatct tttgtataac catagtttat
     5521 atactccatt ctatagagta gcgggtaaga aatagaataa atagtaaaga agctactata
     5581 ccacacatag ggatgaaaaa tattaaattt cacaattatc attgccataa aacttaaaaa
     5641 aatcattgaa aataatggaa ttgtaacatc attattttca ctgcataaaa ttaaagtccc
     5701 tgaaaaaact acacctacta gaagtattat tttatttttt atatcatttg attgtagact
     5761 aaacttcatt tacttttttc ctttaactaa taatttaaac gtaatgcgta ttcaaaaatt
     5821 tgattggcta tgtagtcagt ttttatagca tatttaatat atcgaaacgg attttccatc
     5881 gcattttaat ctaaaccatc agaattattt aattctcttc taatttgagc aaaatagtca
     5941 cttctgcgtt tatttaatac actcgaaaga aatttttttg agaattcaaa ctgttttatc
     6001 accatctttt ccttatccat actaataaaa tctataatag atcccgcaat cgcttgtgaa
     6061 gaggatggag taaatagaca atgtggcccc agcaactctg gaattcctgc tttattagac
     6121 cctatacaag ggcaagcacg gctcatagct tcaattaccg cacgaggtaa cccttcttgt
     6181 aaacttggtt gtatatataa atcaacttta tccaaatact cataaatttg tgatgtagtc
     6241 aattccccta aaaaatggat tctattcgct actcccaatt cctctgcttt cttttttaag
     6301 aaactttgat caccatcacc tgctaaataa taatccaaca aaataccttg tatttctaat
     6361 ctcttcattg cttccaatac aaatctatgg cccttggctc gtacattcac agatgctgtt
     6421 gtcattattg aaattttttg aggattaaat tttttcaact tataaagacg gctcttcaaa
     6481 gatctattct ctacagaggt aatattaaca tttgaagcaa cgatattaga tttaatatta
     6541 ggatatctat cttgtaaata tttttctgtc acgtatatgc aataattagc gttttttaca
     6601 attgatttag ttttggcgta tatatatgga gctaataatt ttccctttaa actatgatac
     6661 cagtaagaat cccaagcatc ccccattatt tctgtcagat acggcttacc tatcttcaat
     6721 gcgtagtctg cagtttttga tccaattata gacggaatac gaacaactat taagtcgcta
     6781 tcaatcattc cttcaataat cttattttta ttttgaccaa atagaacctg atgtagacct
     6841 tctataggga taaatttatt aataaagttc gctttatgat atccttcagg gtatgattcc
     6901 accttctcat aacgactaca tagtacaatc tctccaaatg ctttagcata gcgctcataa
     6961 ataaaataag ctttcggttt taaatatatt tcatttttat agattgtaca tctaaattca
     7021 gtcgctataa atactttcat aatttcatct cccttgataa acgtttctga ataaatatag
     7081 tatcagctgg aatatccttt gttacaacac ttcctgctgc aaccacacta ttctcaccaa
     7141 tactcactcc cttcaagaca atgctgttag ctccaatcca aacattttct ccaatcataa
     7201 ctggggccgt cttaaatttt tttgctttca atccacctgg aacactaaca tcatagtcat
     7261 gatcatatat aagtactcca ggaccacatt ttactccaga tttaatatct atgtatttac
     7321 gacaagctat catacaatta ttactcaaaa atacatcatc agaaatcttg agttttgctc
     7381 cttttctaac tttcaatact cccccggcgt ttactctaat cttttttcct aagattaatt
     7441 tagcattaga ttcctgttcg acagttacat tctttccaaa ttttaaaaaa taatgaaaag
     7501 taagatcctt gtttcgacac acttttaata atatcaagca aatatttgca cgaagtaaac
     7561 caacaatatt ttttataatc ctattcatct aaagctcctt ttattttatc taaataagca
     7621 tctataataa tttgacgaga aaaatattgc tctatataca ttctcccttg aagtcccatc
     7681 tcttttcgtt tttcattttc tagacctaaa aaaacttcca atatagagac tagttcctca
     7741 acatttcccc cttgaaatat atagcctgtc tctctatctt taacaatttc tttgcaacct
     7801 ggattatctg tcgtaattaa aacacgtcct gaactagcgt tttctagtaa tacattgctc
     7861 attccttcac catacacact gggatggata attgcatggg aacgggtaat atgaggtatc
     7921 acatcttttt gttgtcccaa ataataaacg attccttttt tttctaagtc acaaatttta
     7981 agttcataat tactctctgt cggttctata aagccaataa tattaaactc tgttttggga
     8041 tatcgactct taataatttg ggcagcagcc agataagtat ctataccttt ttcttttaat
     8101 atcctaccaa taaaattaaa aacgattgtt tctccttgaa ttccatttcc accatttgga
     8161 tactgttgca caggatactt ttcaatgttc actcctgacc caggtatcag cttagagtca
     8221 cccaaaatca agccaagagt ttttaacatt ttcatattat attcattttg aaaaaaaaca
     8281 caatttgatt tcctaaaaga aattctaaac agtaataaca ccaggcttct tacacaagaa
     8341 cccattgtta agacactacc taaacctgtt acgttattta tatattttat tcctaaaatt
     8401 gttgcagcta ggctagcata tacatttggt ttcacggtat atgtcaagac tacatccggt
     8461 ctatattttc tcaataatct tatataacta agaaatagac gaatatcttt taaagggttt
     8521 attcctcttc tatcaatagt aatatcttca tactcaaatt gaatagactt catcaactct
     8581 atcttatctc cataaggaca tgacactagc acttcatacc catactcaac tagtgactct
     8641 ataacttctt ttcgaaaaca atagatatca tcgtcatgat tagttattaa cataattttt
     8701 ttcttttgta aattcatcaa aataatcttc ctaaaatata attaaccgct actccattat
     8761 cctttacaac tatcatttta aaaatagtaa ttttctataa gtaattgttt ccaaattgtg
     8821 acactttaaa attctataca catatagaac ttacaaacta tttacgaccg taaactccat
     8881 acttatcaac cgagatatcc aatttattta aaacaactcc caggaacagt tcccctgttt
     8941 gttctaattg ttgtttcgct ttttggacat cacgtttatt cgcctcacct gttgctgtta
     9001 tcaagatgga cgcatcacac ttttgagtga taattgccgc atcaataaca attccaatag
     9061 gtggtgtatc aacaatgata taatcaaaat atttacgcaa tgtttcaaac atatcattaa
     9121 aatttttact ttgtaacaag gctgtagggt ttggtgatac agatcccgat tgaactacaa
     9181 ataaattttc aatatttgta tcacataaac cgtgagataa atcagctgtc ccagataaaa
     9241 attctgttag ccctgtaatt ttttcacgag atttaaaaaa tcctgacata actgaatttc
     9301 gaatatcgcc atcgaacaaa agagttttat agcctgcacg cgcaaatgac attgctatat
     9361 ttacggaagt agttgttttt ccttcccccg gattaacaga agtaacggaa attactttta
     9421 gtttatctcc gctcaactgt atatttgtac acaaggtatt gtaatattct tctgccttct
     9481 taatgaactc cagttttttt tgtgctattt ctaatgtcgg catctctctc tcctatttca
     9541 acttacccaa gtttggtaca actcccaaaa gtgtcatctg cagtgcattt tcgatatctt
     9601 ccggacgttt cacacgagtg tccaaaagtt caagaagaag aactataaca ctagttccaa
     9661 tcacccctgc caaaaaacca attagtgtat tgcgtttaat atttggcgaa gacggtgata
     9721 tcgccggtct tgcctcctcc agtgttgtca catcagaaac acgagtaata ctgataattt
     9781 tttgagcagc tacttctctt aaagagttag cgatacggct tgcctcttca ggaactcgat
     9841 cactaactga aacagagaca atacgggtat caactggtac tgttacttta attttattag
     9901 ccaaaccttt tggcatcaaa tctagtttca aatcagaaat aacttcctcc aaaacatcct
     9961 gcgataggac aatttcacga tagtctttaa ccaagtatgc tcctgcctgc aagtcttgat
    10021 tggttaaacc aggcttctct ccctgattac ggttaactag ataaatccga gtcgtactag
    10081 taaactcagg tttgataaca aaagtactgt aggcaaaagc aactgaagaa gttataattg
    10141 ccactaataa aatgaccaac tttcttttcc ataaagctct gaatagttgc aatacatcga
    10201 tttccaaagt gttttgttcc ttcatatttt ctcctaaatt aattgatcca ttataatttt
    10261 tctgggatta tctacaaaaa gttctttcgc ttttttcgct ccatatttct tagcaatgat
    10321 atcatatgcc tgttgcatat atggaggtct actgtctaaa ttgtgcatgt cacttgcaac
    10381 tacatgaact aaatcacgtt ccaaaaaata ccgagctctc tttttcatga atttatattt
    10441 ttcaccaaag aacttaggtt ttgaaacatg ataactattt atctgagtat agcaccccat
    10501 atcaatcagt tcacgaacac gtttttcgtt attctctaaa gcatcataac gttcaatatg
    10561 agcaattact ggcgtgattc ccaacatcaa aatattgctc aatcccgtat gaatctgacg
    10621 ataggaagta tgcatgctaa actcaatcaa ggcataacga ctatcattaa gggtaggaat
    10681 ttcttttttt tctagctttt ctagagcatc cagagtatag tatatctctg cgccataagc
    10741 aatgactaaa tcatctgcta cttcttttgc aatttcccga acctgaagaa agttttctgc
    10801 tatcttctct tccggagttt caaacatgcc cttgcgacgg tgagaggtag agacaatggt
    10861 tctcaccccc tgcctgtagg attctgccaa gagagccttg ctttcctctc ttgacttggg
    10921 accatcatct acatcaaaga cgatgtgcga atggatgtct atcattttat ctaccctcca
    10981 tcacatcctg tatagctgct ttaactacag ttaaactact atcatctatt tccatcacat
    11041 agaggttact gtctggcatt gcataagaag gaagatccat ccgacctgtc ccttttaaat
    11101 cttgagaatt tactttataa ttccctccac tttccaactg agtattcact aaatctatca
    11161 tagtctcaat cggtatattt gtttgaagag aatcctgcaa tccttgaaga atactactat
    11221 agtttttcaa aacctctgta gaagttaact tctgaataat tgctacaatg accttttgtt
    11281 ggttgcgacc acggtcacgg tctccatcgg ttagtgagta gcgttcacgt acaaaaccta
    11341 aagcttgctc agagtctaga tggacattcc ctactgggaa atggaacttc ccatgtagag
    11401 ctgaaaactc ttgatcatta tgaacatcta cccctcccaa taagtcaatc attttcaaga
    11461 aagaagtgaa gttcaatcgc acatagtaat tgatatccac tccatagaga ttttctaagg
    11521 tgtgaatgga cgaatcaact ccataaatgc ccgcatgggt taatttatct ttttgattat
    11581 ttccactatc tgcgattggt acataggcat cacgtggcgt tgtggtcaag aggattttct
    11641 tggtatctcg attgacagtc attaggatat tgacatctga tcgcgacacc gaactaatag
    11701 gaccataggt gtcaattcca ctaacataga tattgaaaga ctgattctta gacgtcttag
    11761 gagcctctac ttttttagtg aatcccttgg tataaatctt ttttatcttc gatgcgtagt
    11821 ctggatactc tgactcgatg atattttcaa agacactatt taggacaatg gccttagtct
    11881 cccctgcaat caaactcttg taagctgcca agtaagacga actctggttg accgtcaaat
    11941 cggtattctg acttgacttg atatcagcta gtagtttttg aatattttca ttatcagtcc
    12001 cagtcggtgc tgtcacactc gtcagttgcg taacattttc gatcttacta tctgctaaaa
    12061 cagcgacact gattgaatat tctgagtaat tagaagtcgc atttaaacga ttggtcagtc
    12121 caacaaactg ctgtactgca aagagcgaca ctgagctgac aaggatagag aacagcaaca
    12181 gaaaaatagt aaacttttca gcttttttat agataatcaa gagtagccct accaaggcaa
    12241 ctagtaggac taacgcagtt accactaggt taagatatct aaaagcaagg atattgtact
    12301 taaagattaa gaacaataaa aaacaaatta acaataaata aatagtcagc aaaacgatat
    12361 taacacttcg cttcactttc tgtgaacgtg attttttaaa acgtctactc atgattaaca
    12421 cctatacctt gaacatcata caattatatc acttttttac ggtaatgtct acacctttat
    12481 tttcactatc tgcatcttta agtatcttag tagacttccc gcgaaccaaa aatatagtaa
    12541 aatgaaataa gaataggaca aatcaatcag gacagtcaaa tcgatttcta acaatgtttt
    12601 agaatcagat gtgtactatt ctagtttcaa tataa
//
LOCUS       DAVBEM010000055        12558 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVBEM010000055 DAVBEM010000000
VERSION     DAVBEM010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12558
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.055"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            339..599
                     /locus_tag="VQ548_001771"
     CDS             339..599
                     /locus_tag="VQ548_001771"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2654578.1"
                     /translation="MSGGETKRVALAKIILKNPPLIFADELTASLDSTTSQGIMKLLL
                     GMKNKNRLIIIATHNPDIWNQADEVINLNQLLQSIYIFYILK"
     gene            complement(703..1173)
                     /locus_tag="VQ548_001772"
     CDS             complement(703..1173)
                     /locus_tag="VQ548_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2654579.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQTLLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(1190..3463)
                     /locus_tag="VQ548_001773"
     CDS             complement(1190..3463)
                     /locus_tag="VQ548_001773"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HET2654580.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLASDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            3810..6911
                     /locus_tag="VQ548_001774"
     CDS             3810..6911
                     /locus_tag="VQ548_001774"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HET2654581.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQGVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRLAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEVREGAFYYIKGKVQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSDELEAKLNEIVMKT
                     IYR"
     gene            6993..8000
                     /gene="pfkA"
                     /locus_tag="VQ548_001775"
     CDS             6993..8000
                     /gene="pfkA"
                     /locus_tag="VQ548_001775"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HET2654582.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            8057..9562
                     /gene="pyk"
                     /locus_tag="VQ548_001776"
     CDS             8057..9562
                     /gene="pyk"
                     /locus_tag="VQ548_001776"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HET2654583.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(10294..10519)
                     /locus_tag="VQ548_001777"
                     /pseudo
     CDS             complement(10294..10519)
                     /locus_tag="VQ548_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            11367..12239
                     /locus_tag="VQ548_001778"
     CDS             11367..12239
                     /locus_tag="VQ548_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HET2654584.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            12252..12416
                     /locus_tag="VQ548_001779"
     CDS             12252..12416
                     /locus_tag="VQ548_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654585.1"
                     /translation="MTVILGFLFLFLMTWWVISIVNSQKPRKNETFIGYIQRYDIDGN
                     GYQSLPCPQN"
     gene            complement(12385..12558)
                     /locus_tag="VQ548_001780"
                     /pseudo
     CDS             complement(12385..12558)
                     /locus_tag="VQ548_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT         3833 a         2183 c         2679 g         3863 t
ORIGIN      
        1 gtgataaaat gtaattgttc catatgaatc tttctaatga gttgttttgt cgcttttcat
       61 tataggtcat atgggacttt ttttctacaa taaaataggc tccataatat ctatagtgga
      121 tttacccact acaaatatta tagaaccctt ttttattgac agtatcagga tatctttttc
      181 aaatttttgg tttgttagat aatgaaaatg tttctatcaa tctagattta ggattaataa
      241 atcgtaaatg taattataaa gaaaaagata agttaaaaaa agatgtatta gcaagagttg
      301 gtctaactca tattcatcta taacaaaaga tatatgaatt gtctggcggt gaaacaaaac
      361 gtgttgcttt agcgaaaatc attcttaaaa atccaccatt aatattcgcg gatgagttga
      421 ctgcatcact cgattcgacg acttcacaag gaattatgaa attgttatta ggtatgaaaa
      481 ataaaaatcg tctaatcatc attgcaactc ataatcccga tatttggaat caagcagatg
      541 aagttataaa tttaaatcaa ttattacagt caatatatat cttctatatt ttaaagtaat
      601 tttatctgaa tccgttaaga gactattgtc ccaggctctt tctgatgtta aagactttct
      661 accaggtttt ttaaaagcat aattgttagt tgtagtcatt tattattctt caaagaaaaa
      721 tggtggggcg aattttttca gttcttcaaa gcacttttga gcagtatctg catcttcaca
      781 gatgataaga cagacatcat taccacaaag ggtagcgata gcgtcaggga agctcaaagt
      841 atcaatgata gaaccaaagg attgagccag tccaggaagg gtttttagta ggacttggtg
      901 ttgaactggg cgcatccaga caagggcgtc ttccatgtag agttcgagac gtttttccca
      961 ttttgagatg gaaccattgt taagaacata ataagcgcta tcttcttcgc ggacttttga
     1021 taggttcata tttttgatgt cgcgtgagag ggttgcctga gttacttgaa tgtcgttctc
     1081 agcaagaagg gtttgcaact cagcctgtgt atgaatcttg ttttttgtga taagagcgcg
     1141 tataagttgg tggcggtgtt ctgatttatt cataataatg taactccttt tagcaaggta
     1201 aggtaagcat ggactgagcg aggtcgacag tcaagtggta gtctgtattg tcacggatgg
     1261 tgatttcaaa gtcagtagta tagaggacta aacggagagt gtctccttct tttagcttgt
     1321 aaatagttgg ctgcagttca aattgaacgt ccatccattc atctgcagta atatcctcta
     1381 ctaacagtaa atcatttcta ttttgtaaat taaggtaacc ttttgtcacg actctttgtg
     1441 cctctggtct aaatggcaat tcacagagat tttccaacat gtgatagcga ccgttgtcaa
     1501 tggttctagc acttaaaata gctggataag gttgtaggta tttcttttgc ccaaattcta
     1561 gcagttgggc agataagagc cccttgtttg tactggattt gatacgaaga ttgagctgag
     1621 cgcgaccgtt taggtggaga tctttagtca caggaaggtt aatagtaatc tgattagctt
     1681 tcccttgata gagctctgta ttgaaggttt ggtatgtctt accatagcgc tcaaaatcct
     1741 tatctgggta ctggttttga atagcttgct cttcttgacc aagtgagaag gtttcacagt
     1801 tttcttgccc accgaagtta tcaagtgata accaagtctg tggagctgta ttgtcctgcc
     1861 agataacagt aggaagttga aagtctgttt cctgtcctag taatttcttg gtcaataagg
     1921 catttatgga ctcacggaag tcaattgatt gccaattgtt catgtaaaca tgggcaccat
     1981 tatggaaaaa gagatgcttg tgtatatgag taggaagagc atggaacatc tggtaaacat
     2041 gaagtggttt gacattccaa tcctgagaac catgagtaaa gacaacctct gcctttactt
     2101 tatgggcatt gagcagataa ttgcggtcat gccaaaactg attgtagtcc ccagtttttc
     2161 ggtctagttg agctttcact ttttctaagt cagcttggtg agcttcattg ccacggatat
     2221 agtcgctagc caagagatta cgagaatagg ttaactcagc aagggagtca aagtcctcac
     2281 ctggataacc acctgggcta gtcaccagac cgttttcacg gtagtagttg taccatgatg
     2341 aaattcctgc ctcggcaatg ataacttcta aaccatcgac tcctgtagtc gcaagaccat
     2401 tggacatggt acctagatag gaaagtcccg ttgtagcaac ttttccgttt gaccaatcag
     2461 ccttgacttg acgctggcgc gtgtgatcag taaaggcacg gcaacggccg ttaagccaat
     2521 cgatgacatt tttataagcc tcgatttgct ggtagtctcc attagtcatg aaacctgtcg
     2581 agtctttggt accaacacct gagacataga gattggcaaa gcctctcgga aggaagtagt
     2641 cgtttagtgt atagctagag ttgatgtgag ttagcttttc ctcagcctct gctataagct
     2701 cagctttacc ttggggttgg acgagattta gttgaggttt ctctagctca atcttgtgag
     2761 gaagtttaac ctcaagctcg ccctccatct tgtagagagc cttgtcacta gccttgtcat
     2821 tggttccctg atgataaggg ctggctgtca tgatggcagg gatttttcca tcaaaacgag
     2881 ggcgaataat gctaaccttt actaggtctg atagcccttt ttggtcagta tcgacacgag
     2941 actcaacgta aacgacttca cgaatgacat cctggttaga aaaagtagcc aaactcttgc
     3001 cgttaaagta gtggtagtca ttatcctccg gaataagacc atcactaaca agttggtcga
     3061 taagagtatt tccttttttg gtgcgagtat tgagtaactg atagagattt tcaatcaagt
     3121 caccatatat aatgggaaat ccagtttctt tacgaaaaac gtcactatct tcgaagtcaa
     3181 ccaaataaga aaagcctaaa agttgaaaag caacagtata aaaaatatct gctgtcagtt
     3241 catcttctga ttgaaaaaat gtcagcaggt ctgttttttt atcagctgct aggatagaaa
     3301 gtgggtagtt ggtgtcttga taagtgaaaa agaaacgacg taaaaaggtt tcaagtgagt
     3361 ctttgtgatt ggctgtattt tgtaaatcaa agccacattt ttttagttca gataagacat
     3421 tttcttttgg aaaattgata taactatatt gattaaaacg catagaacct ccatatagaa
     3481 tgacagttaa ggttattata tcaaaaaaaa agcagaaagg gaattgttaa cttcaaaagg
     3541 aaataatcca ataaaaatga ataaagtact aaattcaata tagagaacag agtaacaata
     3601 agaataaata gatagggtat aaaagttcta ggagatttat attatatgct ttctgttttt
     3661 atatacaata tagtataaat ataaaaatga tgacaaaaat acaaatgaat agaaaataaa
     3721 ttagtaagct gatgaaattt ttctcaagag aagccattta taggtgaaaa tggtataata
     3781 tagtgagaag gatagaggag aagtgtaaat tgatcgcaca actagataca aaaacagtct
     3841 atagttttat ggaaagcgtc atttcgatcg aaaagtatgt gagagcagct aaagaatacg
     3901 gctacactca tttggctatg atggatattg acaatcttta tggcgctttc gactttctag
     3961 agattacaaa aaaatacggc attcatcctt tgctagggct tgaaatgaca gtgtttgtag
     4021 atgatcaggg agtgaatttg cgctttttag ctctatctag tgtgggctat cagcagttga
     4081 tgaagctttc gacagccaag atgcaggggg agaaaacttg gtcagtcctg tcccagtacc
     4141 tggaggatat cgcggtcatt gtgccttatt ttgatagagt tgagtcgtta gaactaggct
     4201 gtgattacta tataggggtt tatccagaaa cactagcaag cgaatttcat catcctatct
     4261 tacctcttta tcgggtcaac gcttttgaaa gcagggatag agaagttctt caagttttaa
     4321 cagcgattaa agaaaatcta ccgctcagag aagttccctt gcgttcgaga caagatgtct
     4381 ttatatcagc aagttcttta gagaaactat tccaagagcg ttttccgcaa gctttggaca
     4441 atttagaaaa gcttatttca ggcatttctt acgacttgga tactagtctg aaactgcctc
     4501 gttttaatcc agctagacca gcagtagagg agttgagaga gcgtgctgaa ctggggcttg
     4561 ttcagaaggg gttgactagt aaagaatatc aagatagact agaccaagaa ttgtctgtta
     4621 ttcatgatat gggctttgat gattatttct tggttgtttg ggatttgttg cgttttggac
     4681 gatcgaatgg ctattatatg ggaatgggaa ggggttctgc agtaggcagt ttggtttctt
     4741 atgccttaga catcacgggg attgacccag tagagaaaaa tctgattttt gaacgctttc
     4801 ttaatcgtga acgctatacc atgcctgata ttgatattga tatcccagat atttatcgtc
     4861 cagattttat cagatatgtt ggtaataaat atggtagtaa acatgcggca caaatcgtta
     4921 ctttttcaac ctttggagcc aagcaagctc ttcgagatgt cttgaaacgc tttggtgtgc
     4981 cagagtatga attatctgca attactaaga aaatcagttt tcgtgacaat cttaagtcgg
     5041 cctatgaggg caatctccag tttcgtcagc aaatcaatag taagttagaa taccaaaaag
     5101 cttttgagat tgcttgcaag atagagggct atccaaggca aacctctgtc catgcggctg
     5161 gtgttgtaat tagtgaccaa gatttaacca actacattcc tctaaagtat ggtgatgaaa
     5221 ttccactgac tcagtatgat gctcatggag ttgaggctag cggacttttg aagatggact
     5281 ttctgggact acgaaatttg acctttgtcc agaagatgca agagttgctt gctgaaacag
     5341 aaggtattca tctgaaaatt gaagaaatcg atttagaaga caaagaaaca ttagctttat
     5401 ttgcctctgg taatacaaaa ggtatctttc aatttgagca accaggtgcc attcgtctgc
     5461 ttaagcgtgt gcaaccagtc tgttttgaag atgtcgtcgc gactacttct ctaaatcgac
     5521 cgggtgctag tgactatatc aataattttg tggcaagaaa gcatgggcag gaagaagtga
     5581 ctgttctgga tccagtactg gaggatattt tggctccaac ctacggcata atgctctatc
     5641 aggagcaggt tatgcaggtt gcccagcgac ttgccggatt tagtcttggg aaagccgata
     5701 ttttgcgtcg ggctatgggg aaaaaggatg cctctgccat gcatgagatg agggcttcct
     5761 ttattcaagg ttcattagaa gctggtcata ctgtggaaaa agcagagcag gtctttgatg
     5821 ttatggagaa gtttgcaggt tatggtttta acaggtcaca cgcctatgcc tactcagcct
     5881 tggccttcca gttggcttat ttcaaaacgc attatccagc cattttttat caggtcatgt
     5941 taaattcttc caacagtgat tacttaatag atgcacttga agcaggtttt gaagtagcct
     6001 ctctatccat caacaccatt ccctatcacg ataaaattgc caacaaggcc atctatctag
     6061 gtttgaaatc cattaaagga gtcagtaatg atttagctct ctggattatt gaaaatagac
     6121 cttattctaa cattgaagat tttatagcta aattacctga gaattatctg aaacttcctc
     6181 tgctagaacc tttggtaaaa gttggtcttt tcgattcatt tgaaaaaaat cgtcaaaaag
     6241 tatttaataa cttagctaat ctatttgaat ttgtgaaaga gttgggaagt ttgtttggag
     6301 atgctattta tagttggcag gaatcggaag attggacgga acaagaaaaa ttttatatgg
     6361 aacaagagct tttagggata ggtgtcagca aacatccact acaagctatt gcaagtaagg
     6421 ctatttaccc gattacccca atcggaaatt tgtcagaaaa tagctatgct attatcttgg
     6481 ttgaagttca gaaaataaaa gtgattcgta ccaaaaaggg tgaaaatatg gccttcttac
     6541 aggcagatga tagtaagaaa aaattggatg ttacactctt ctcagattta tatcgacagg
     6601 ttggtcagga agtaagagaa ggagcattct actatatcaa agggaaagtc caatcacgtg
     6661 acggtcgtct gcaaatgatt gcacaagaaa taagagaagc agttgctgaa cgcttttgga
     6721 tacaggtgaa aaatcatgaa tcggatcaag aaatttcacg tattttagaa caatttaaag
     6781 gcccaatccc agtcatcatc cggtatgaag aggaacagaa aaccatcgtt tctccccatc
     6841 attttgtagc taaatctgat gaattagagg cgaaattgaa tgaaatcgtt atgaaaacga
     6901 tttatcgcta aaaatacgga aaatagaaga attttaaaat caaatgtgat ataatcaaga
     6961 agaatgttaa aagaaaaagg agcataacca atatgaaacg tattgctgtt ttgactagtg
     7021 gtggagacgc ccctggtatg aacgctgcca tccgtgcagt tgttcgtcaa gcaatttcag
     7081 aaggaatgga agtgtttggt atctatgacg gatatgctgg tatggttgcc ggtgaaattc
     7141 atcccctaga tgcagcttca gtaggggaca tcatttctcg tggtggtact ttccttcact
     7201 cagctcgtta cccagagttc gctcaacttg aagggcaact taaagggatt gagcaattga
     7261 aaaaacacgg aattgaaggt gtagttgtta tcggtggtga cggatcttac cacggcgcta
     7321 tgcgtttgac tgaacatggc ttcccagcta ttggtcttcc aggtacaatc gataacgata
     7381 tcgttggtac tgactttaca atcggttttg acacagcggt tactactgcc atggacgcta
     7441 tcgataagat tcgtgataca tcatcaagtc accgtcgtac ttttgtaatc gaagttatgg
     7501 gacgtaacgc tggtgatatc gctctttggg ctggtattgc aactggtgct gatgaaatca
     7561 tcatccctga agcaggcttc aagatggaag atatcgtagc aagcatcaaa gctggttatg
     7621 aatgtggtaa aaaacacaat atcatcgtct tagctgaagg tgtgatgtca gcggctgaat
     7681 ttggtcaaaa acttaaagaa gctggagata caagcgacct tcgtgtaaca gaacttggac
     7741 atattcaacg tggtggttct ccaactgcgc gtgaccgtgt tttggcgtca cgtatgggtg
     7801 cacatgctgt taaacttctt aaagaaggta tcggtggtgt tgcggttggt attcgtaacg
     7861 aaaaaatggt tgaaaatcca attcttggta ctgcagaaga aggggcattg tttagcctta
     7921 ctgcagaagg taagattgtg gttaacaacc cgcacaaagc cgatattgag ctatctagct
     7981 tgaataagag cttgtcataa tttacaattt agttaataag accaaaaagg tcatatataa
     8041 aggagtcaca aaaatcatga acaaacgtgt aaagatcgtt gcaactttgg gtcctgcggt
     8101 agaaatccgt ggtggtaaaa aattcggtga ggacggatac tggggtgaaa aacttgatgt
     8161 tgaagcttca gctaaaaaca ttgctaaatt gattgaagct ggtgctaaca cattccgatt
     8221 caacttctca cacggcgacc accaagaaca aggtgagcgt atggcaactg ttaaacttgc
     8281 ggaaaaaatt gcaggtaaaa aagttggttt ccttcttgat acaaaaggac ctgaaatccg
     8341 tacagaattg ttcgaaggtg aagctaaaga atattcatac aaaactggtg aaaaaattcg
     8401 tgttgcaact aaacaaggaa tcaaatcaac tcgtgaagtg attgcgttga acgttgctgg
     8461 tgctcttgat atctatgatg atgttgaagt tggtcgtcaa gttttggttg acgatggtaa
     8521 acttggtctt cgtgtggttg ctaaagatga tgcaactcgt gaatttgaag ttgaagttga
     8581 aaacgatggt atcatcgcta aacaaaaagg tgtgaacatc cctaacacta aaattccttt
     8641 cccagctctt gctgaacgcg ataacgacga tatccgtttc ggtcttgaac aaggtatcaa
     8701 cttcatcgca atttcattcg tacgtactgc aaaagatgtg aacgaagttc gtgcaatctg
     8761 tgaagaaact ggaaacggac atgttcaatt attcgctaaa atcgaaaacc aacaaggtat
     8821 cgataactta gacgaaatca tcgaagcagc tgatggtatt atgattgctc gtggtgatat
     8881 gggtatcgaa gtaccgttcg aaatggttcc agtttatcaa aaaatgatta tcaagaaagt
     8941 caatgctgca ggtaaagttg ttatcactgc aacaaacatg cttgaaacaa tgactgaaaa
     9001 accacgtgca actcgttcag aagtatcaga cgtattcaac gctgttatcg acggaactga
     9061 cgctacaatg ctgtcaggcg agtctgcaaa cggtaaatac ccactcgagt cagtaactac
     9121 aatggctaca atcgacaaga atgctcaagc tcttcttaat gaatacggac gtcttgattc
     9181 agattcattt gagcgtaact ctaagacaga agtaatggct tctgctgtta aagatgctac
     9241 tagctcaatg gatatcaaat tggtcgtaac tcttactaag acaggtcata ctgcacgttt
     9301 gatttctaaa taccgtccaa atgctgacat cttagcattg acatttgacg aattgacaga
     9361 acgtggcttg atgttgaact ggggtgttat cccaatgttg acagatgctc catcttcaac
     9421 tgacgatatg ttcgaaatcg ctgaacgtaa agcggtagaa gcaggtctcg ttgagtcagg
     9481 cgatgatatc gttatcgttg ctggtgtgcc agtaggagaa gctgttcgca caaacacaat
     9541 gcgtatccgc acagtacgtt aagaaaaata taaaaaccta tcatatccag ctttagagct
     9601 tgtgtgatag gctttttgta tagagggtaa gaaataggca aaactttcat aatggattga
     9661 tactcttcga aaatcaaatt caaaccacgt cagcgtcgcc ttaccgtata tatgttactg
     9721 acttcgtcag ttctatctac aacctcaaag cagtgctttg agcaacctgc ggctagcttc
     9781 ctagtttgct ctttgatttt cattgagtat gaaataagat atgcacaaat tgattaggaa
     9841 attcaaatga atttctacaa atgttttagc aatcgtaatg tacttgtcta gattcgatct
     9901 gatatatttt cgatttaatg atatggtatt taaaacctcc aaagtagctt gctccattct
     9961 tttacttacg tgagtgtaga tgttatttac tgttttagcg tttttgtgtt ccactctaac
    10021 cattatagca ttcttctcag ctagtgtact aaggagtgtg tgcctgaaaa tatgggaact
    10081 aaggggctgg tttatcggtt tctctagttt agtatttgcc ttttgcaaag tgatgttaaa
    10141 tgcctttctc taaatttaca tatcactatt gtttaacaaa atctaatcta ctttaggtca
    10201 cttattcttt ttttgaaatg tagaatgaac tttttcaaag tttttcgaat cttttaaaat
    10261 ctgtttgttt tatatcgcca ttctccccct tttttaattc tccctatata gcctgacaac
    10321 tttcccgatg gtacgaatat ggttgctttc gtctaggtgg atgtcggggt atttgggatt
    10381 gagttttttt aaggtagcct tggcggagtt tcttgacata gttagcgccg tctacttgga
    10441 agatgccgat ggtattatag tcaatctgtg gggtattctt gataaatagg tagtcgctgt
    10501 ttcttatctt tggctccatg gacttgctga cgacataagc gattgggtcg tagtcgtctg
    10561 ggataatgga aactccataa ctaaatcgtc gtcctgcatc gagcggctac ctgcagagat
    10621 aaactaccta acacgagagt aagtagtctg tctgtagtcg tccagtctga tgatttttac
    10681 gatatttcgt ttttctgctc atacagttgc ctctcggcat aggtcagaac tttaccttgt
    10741 ctgggtggtg cccgttggtc gtagatagat tggatatcgc taggagaatc cttttgaact
    10801 ggaggaaaga gggtatcaat caagctactg aatactttag ctaagtcaaa tatagtattt
    10861 ttcttagtag acctaaccct tttttcataa tttccaatgg tgtttttact tataccaatc
    10921 ttagtaccca attcttattg agtccaacca ttactagtct atattgtttt atagttgatt
    10981 gagtttggaa tagtacgctg tagctgctaa aacatttcta ggaattaatt tgactttcct
    11041 aatagagttg ttcatatctt atttcaatct actatgtttt tcacctctaa caatcgcaat
    11101 ctcttcttta tccatgaatg aaatcgcttt ctatttttgt aagtaaagca tcacacgaaa
    11161 tccacgaaaa tgaaaacctt tgttgtgttt tcgtaaaaaa tttgttgaca gagcacgaaa
    11221 cgcctactat aattaaatca agcttaagga aataacaaaa aaacaaatcg gagggaaaga
    11281 cgatgaacac attaaatgag aaagtaatca atatctgtaa agcagtagtt aaagaaactt
    11341 taatccaaga catttaggag aaagaaatga agaaatcaag aaaattagcc acattaggaa
    11401 tctgttcagc cttgttttta ggcttggctg cttgtcaaca acaacatgct acttctgagg
    11461 ggacgaatca aaggcaaagc agttcagcga aagttccatg gaaagcttca tacaccaacc
    11521 taaacaacca ggtaagtaca gaagaggtca aatctctctt atcagctcac ttggatccaa
    11581 atagtgttga tgcatttttt aatctcgtta atgactataa taccattgtc ggctcaactg
    11641 gcttatcagg agatttcact tcctttactc acaccgaata cgatgttgag aaaatcagtc
    11701 atctctggaa tcaaaagaag ggcgatttcg ttgggaccaa ctgccgtatc aatagttatt
    11761 gtcttttgaa aaattcagtc accattccaa agcttgaaaa gaatgaccaa ttgcttttcc
    11821 tagataacga tgcgattgat aaaggaaagg tctttgattc acaagataag gaagagtttg
    11881 atattctatt ttcgagagtt ccaactgagg caactacaga tgtcaaggtt cacgctgaaa
    11941 agatggaaac attcttctca caatttcaat tcaatgaaaa agctcgaatg ctgtctgtag
    12001 tcttgcacga caatctggat ggcgagtatc tgtttgtagg ccatgttggg gtcttagtac
    12061 ctgctgatga cggtttctta tttgtagaga aattgacttt cgaagagccc taccaagcga
    12121 ttaaatttgc tagtaaggaa gattgctaca agtatttggg caccaagtat gcggattata
    12181 caggcgaggg actggctaag ccttttatca tggataatga taagtgggtt aaactttaat
    12241 agtgttatga tatgacagta atcttaggat ttttatttct atttttgatg acttggtggg
    12301 ttatttcaat cgttaatagc cagaaaccac gcaaaaatga aacatttatt ggctatatcc
    12361 aaagatacga tattgatggg aatggctatc aatcattacc gtgtcctcag aactgagagg
    12421 agttcttgaa accgtaaaac cgctttgaac aagagttact tcaacccatt ggctccgacg
    12481 gagtaagttg ctttcgtgaa taccaaaatc agccgcaatt tgttcataag ttcgatattc
    12541 tcgcacatat tgaagagt
//
LOCUS       DAVBEM010000056        12517 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVBEM010000056 DAVBEM010000000
VERSION     DAVBEM010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12517
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.056"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            259..2550
                     /gene="pcrA"
                     /locus_tag="VQ548_001781"
     CDS             259..2550
                     /gene="pcrA"
                     /locus_tag="VQ548_001781"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HET2654586.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTTYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2593..3273
                     /gene="radC"
                     /locus_tag="VQ548_001782"
     CDS             2593..3273
                     /gene="radC"
                     /locus_tag="VQ548_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HET2654587.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3270..3959)
                     /locus_tag="VQ548_001783"
     CDS             complement(3270..3959)
                     /locus_tag="VQ548_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET2654588.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYNLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(3977..4618)
                     /locus_tag="VQ548_001784"
     CDS             complement(3977..4618)
                     /locus_tag="VQ548_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HET2654589.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4701..4916)
                     /locus_tag="VQ548_001785"
     CDS             complement(4701..4916)
                     /locus_tag="VQ548_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET2654590.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(4924..5271)
                     /locus_tag="VQ548_001786"
     CDS             complement(4924..5271)
                     /locus_tag="VQ548_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HET2654591.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFSLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5276..6391)
                     /locus_tag="VQ548_001787"
     CDS             complement(5276..6391)
                     /locus_tag="VQ548_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2654592.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6401..7360)
                     /locus_tag="VQ548_001788"
     CDS             complement(6401..7360)
                     /locus_tag="VQ548_001788"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET2654593.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7473..8042)
                     /locus_tag="VQ548_001789"
     CDS             complement(7473..8042)
                     /locus_tag="VQ548_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HET2654594.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAEDYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8170..8841
                     /locus_tag="VQ548_001790"
     CDS             8170..8841
                     /locus_tag="VQ548_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HET2654595.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            8825..9643
                     /locus_tag="VQ548_001791"
     CDS             8825..9643
                     /locus_tag="VQ548_001791"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HET2654596.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            9640..10536
                     /locus_tag="VQ548_001792"
     CDS             9640..10536
                     /locus_tag="VQ548_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2654597.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10580..11554
                     /gene="pta"
                     /locus_tag="VQ548_001793"
     CDS             10580..11554
                     /gene="pta"
                     /locus_tag="VQ548_001793"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HET2654598.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(11870..12517)
                     /locus_tag="VQ548_001794"
                     /pseudo
     CDS             complement(11870..12517)
                     /locus_tag="VQ548_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433508.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3637 a         2388 c         2696 g         3796 t
ORIGIN      
        1 tcgtaaacgc ttcggattac gaatgaattt gattgctggc attatcaatc atgaactagg
       61 attctagttt tgcaggaagt ctattgaggt attgagctag tttatgaaaa aattgggtga
      121 aaaagtcgag tgttttagaa acccacagtg tagtattcta gtttcaatcc actatatttt
      181 gctactcccc gtaaagtttc tattttccct gatttctgat ataatagaaa tattgacttc
      241 aagagtaagg aagagaagat gaacgcatta ttaaatggaa tgaatgaccg tcaggctgag
      301 gcggtgcaaa cgacagaagg tcccttgcta atcatggcag gagctggttc tggaaagact
      361 cgtgttttaa cccaccgtat cgcttatttg attgatgaaa agctggtcaa tccttggaat
      421 atcttggcca ttacctttac caacaaggct gcgcgtgaga tgaaagagcg tgcttatagc
      481 ctcaatccag ctactcagga ctgtctgatt gcgaccttcc actccatgtg tgtgcgtatt
      541 ttgcgtcgcg atgcggacca tattggctac aatcgtaatt ttacaattgt ggatcctggt
      601 gaacagcgaa cgctcatgaa acgtattctc aaacagttga acttggatcc taaaaaatgg
      661 aatgaacgaa ctattttggg gaccatttcc aatgctaaga atgatttgat tgatgatgtt
      721 gcttatgctg ctcaagctgg cgatatgtat acgcaaattg tggcccagtg ttatacaacc
      781 tatcaaaaag aacttcgtca gtctgaatcc gttgactttg atgatttgat tatgctgacc
      841 ttgcgtctct ttgatcaaaa tcctgatgtt ttgacctact accagcaaaa attccaatac
      901 atccacgttg atgagtacca agataccaac cacgctcagt accaattggt caaactcttg
      961 gcttcccgtt ttaaaaatat ctgtgtggtt ggggatgcgg accagtctat ctacggttgg
     1021 cgtggtgctg atatgcagaa tatcttggac tttgaaaagg attaccccaa agctaaggtt
     1081 gttttgttgg aggaaaatta ccgctcaacc aaaaccattc tccaagcggc caacgaggtt
     1141 attaaaaata ataaaaatcg ccgtcctaaa aatctctgga ctcaaaacgc tgatggggag
     1201 caaatcgttt actatcgtgc tgatgatgag ctggatgagg ctgtatttgt agccagaacc
     1261 atcgatgaac ttagtcgcag tcaaaacttc cttcataagg attttgcagt tctctatcgg
     1321 actaatgccc agtcccgtac aattgaggaa gccctgctca agtctaacat tccttatacc
     1381 atggttggcg gaaccaaatt ctacagccgt aaggaaattc gcgatattat tgcttatctc
     1441 aaccttattg ctaatttgag tgacaacatt agttttgagc gtattatcaa cgagcctaaa
     1501 cgtggaattg gtctaggtac agttgagaaa atccgtgatt ttgcaaattt gcaaaatatg
     1561 tctatgctgg atgcttctgc taatattatg ttgtctggta tcaagggtaa ggcagcccaa
     1621 tctatctggg attttgccaa tatgatgctt gatttgcggg agcagctaga ccacttaagc
     1681 attacagagt tggttgagtc cgtcctagaa aaaacaggtt atgtcgatat tcttaacgcc
     1741 caagcgactc tagaaagcaa ggcaagggtt gaaaatatcg aagagtttct ttctgttacg
     1801 aagaactttg atgacaccac tgatgtgaca gaagaggaaa ctggtctgga caaactgagt
     1861 cgtttcttaa atgacttggc tttgattgcc gacacagatt caggtagtca ggagacatca
     1921 gaagtgacct tgatgaccct gcatgctgcc aaaggtctcg aatttccagt tgtctttttg
     1981 attgggatgg aagaaaatgt ctttccactt agtcgtgcga ctgaagatcc agatgaatta
     2041 gaagaagagc gccgtctagc ctatgtaggt atcacgcgtg cagagaaaat tctctatctg
     2101 accaatgcca actcacgctt gctttttggt cgtaccaatt ataaccgtcc gactcgtttt
     2161 attaacgaaa tcagttcaga cttgcttgag tatcaaggtc tggctcgtcc tgcaaataca
     2221 agctttaagg catcatatag cagtggtagt atttcctttg gtcaaggtat gagtttggct
     2281 caggctcttc aagaccgtaa acgcggtgct gccccaaaat cgatccagtc aagcggtctt
     2341 ccatttggtc aatttacagc tggcgcaaaa tcagcatcta gcgaggcaaa ttggtccatt
     2401 ggtgacattg ctctccacaa gaaatgggga gagggaactg ttctggaagt ttcaggtagc
     2461 ggtgctaggc aggaattgaa aatcaatttc ccagaagtag gtttgaaaaa acttttagcc
     2521 agtgtggctc caattgagaa aaaaatctaa ttttccatcc ttctcacgaa taataaagtg
     2581 aggaggattt ttatgtacag tatttcattc caagaagatt cactattacc aagagaaagg
     2641 ctggccaagg aaggagttga agcgcttagt aaccaagagt tgctagctat tttactcagg
     2701 acaggaacac gtcaagctag cgtttttgaa attgcccaaa aagtcttgaa caatctttca
     2761 agcctaacgg atttgaaaaa aatgaccctg caggaattgc agagtttgtc tggtattggg
     2821 cgtgttaagg ccatagaatt acaagctatg attgaactgg ggcatcgtat tcacaaacac
     2881 gagactcttg aaatggaaag tattctcagc agtcaaaagt tggccaagaa gatgcagcag
     2941 gaattagggg ataaaaaaca agagcacctg gtggcactct atctcaatac tcaaaatcaa
     3001 atcatccatc agcagaccat ttttatcggt tctgtaactc gtagtatcgc tgaaccgcga
     3061 gagattcttc actatgcaat caagcatatg gcgacttctc ttatcttggt ccacaatcat
     3121 ccttcaggag cggtagcgcc tagccaaaat gatgatcatg tcactaaact tgttaaagaa
     3181 gcctgcgaat tgatggggat tgttctcttg gaccatttga ttgtctctca ttctaattac
     3241 tttagttatc gtgaaaagac agatttaatc taaagttcat taacgacata gtcaaagagt
     3301 tttttatctt tgggacgatt ttcaaaaaga agttctggat gccattggac accgagaaag
     3361 gcgacatcat ccgtactcat gacagcctca atgataccat ctttaggatc atgagccaca
     3421 acttttaaat ttggtgctaa gtccttgatg ctctggtggt ggaaggagtt gatatgagag
     3481 atttctccat agatttcttg gagaacggta tctggttctg ttaccaagcg ttgagttgtg
     3541 tactcaacag aagaatcctg ccaatggtct tcgatatctt ggtacaaagt tccacccatg
     3601 gcaacgttaa agagttgggt accacggcag acagagaaaa tgggcttttt ctgtttaata
     3661 gcttccttga tgagggccag ttcgaagata tctctttgaa ggttatagtc atcgctatca
     3721 atggttttgg gttcgccata aaattttgga tcgacatttt gcccacctgt caagatgagc
     3781 ttgtcaatca aactgatata gtggcaggcc atttcttgat caccaatcgg taggatgatg
     3841 ggaatccctc cagcatcttt aacgccttca acaaagcctt ttgctgcgta gctcatcatg
     3901 atgtcatcat ctggatgagc tttttcgttt cctgtaatcc caataactgg ttttttcata
     3961 aaatgatttt cgctttctaa tcctcttttc gcatgaagta gaggagggtt tggagttcac
     4021 ttgtcaaatc gacatactga acgaccacgt cttttggtaa atgcagatgg actggtgaaa
     4081 aactgagaat tcctttcaca ccagcatcaa ccaagagatt agcaacctct tgtgacttga
     4141 cgctgggaac agttaggata gcagtcttca catcagcatc cttgatttta tccttgatct
     4201 gagaaatccc gtaaatggga atcccgtcag gagtttgggt accgacttca ggatggtcgt
     4261 ctaggtcaaa ggccatgata atcttcatct tgttacgttc gtggaagcgg tagtggagaa
     4321 gggcatggcc catatttcca ataccaacca gcatgacatt ggtaatagag ttgtcattga
     4381 gcaaatcggc aaaaaatgtc attagttttt tgacatcata gccaaaacca cgacgaccaa
     4441 gttcaccaaa ataggaaaaa tcacgacgta cggtcgctga atcaataccg atagcctctg
     4501 caatttgctt agagttggca cgttcaatct tttctgcatg aaatctctta aaaattcgat
     4561 agtagagaga gagtcttttt gctgtagctt ttggaatagc aaactgttta tctttcacaa
     4621 aatcacaacc tttctattct tctattttat agaaacattg tgaaaaaatc aacaaaaata
     4681 agaaaaaact aagaaaaatc ttagttttga tgtaaaaaat ctgcatgaga tagaaaacgg
     4741 tagaggtctc cgaccagacc ctgataaact ttttggcccc taaaagtcag agaagtcaca
     4801 taaagtgtat ctggtaaggt tacacatcct gacaaagtca acatgagagc ctcatgatcc
     4861 tcatacttga gagtacgctc tacatgatag cagtccttat aggtcagttc aaacattttg
     4921 gctctatctt tccgattttg taaagacacc acgttctacc aagctatcca tgaggaagta
     4981 gaatttttcc tgatgaatat ggtggtcttc tgatttgaaa atatcaacta gacgaaggct
     5041 aaacttgtca gtgatattga ttttagcccc tgtaagttcc ttgttaatga tgattttgag
     5101 ttggaagcct tcaccgctgt ttggcacttt ttccaaaagg cgagtcagtt catagttacc
     5161 aaccttagtt tcaaaaaagg tgttatcttt gagggtgaat tttttaacag aagggctaag
     5221 agtgtaatcg taacgacaat tttttaactg aatgattttt tcaaatgcca tatggctaac
     5281 ctccgataat ttcttttaag gtttttgcga gggtttgtag gtcttcaacg gtattttgtg
     5341 gcgacaaact gatgcgaagg gattccttca agcgttctga atttgcgcca tacatggctt
     5401 caagaacatg gctggattgg acaacgcctg cagtacaggc tgagccagta gagattgaaa
     5461 ttccagctaa atctagccga aggagtaaga ggtcattttt ctgaccagga aatccaatat
     5521 tgagaacata agggagatga tgttttcctc tattcaagta atactgaatg ccctccagct
     5581 ctgccagaaa ggcggtttct agattttgta catgttgaaa atgttcttct tgtttttcta
     5641 ggtcttcttt tagggctgca accatgccta cgatagcagg cagattttca gttcctgcac
     5701 gttttttctg ttcctggtct ccgccatgta gataggaatc aaagtccatg ctagatgcgt
     5761 agagaaaacc gattccctta ggaccatgga atttgtgggc agaagcagtg agaaaatcaa
     5821 tgcccaattc ttctgaatga attgggattt taccaatagc ctgaactgca tcaacatgat
     5881 aggcagcagg gtgttgcttg agtatttggc caatttcagc gatgggcagt aggtttcctg
     5941 tctcattatt ggcaaacatg gtagaaacca aaatcgtatc gtcacgtaaa gccttttgaa
     6001 tttgctgggc tgtgatttct tgattttctg gctggataat ggttgcttca aacccaaagt
     6061 gttgaaccaa gtaatcaatt gtttcaagga cagcatggtg ctcgatggca gttgtgatga
     6121 tatgttttcc ttgttcttgg tgacgaagac agtagccaat gatggtagta ttattgcctt
     6181 cagtcccacc agaagtgaaa aagatatgtt gaggttttgt ccttagtaac tgggctagtt
     6241 cctgacgggc ttctcgcaag agtttgccag cttgacgacc atgaccatga atactagaag
     6301 gatttccgtg ggtttcttgc ataaccttgg tcatagctga aatagcaact gctgacatag
     6361 gagtcgttgc agcattgtcc aaataaatca aagaatcacc ttatttcttt ttattgtagg
     6421 caaagagtgg gctgactggt tttctttcgt gaatacggac gatagcatca ccaattaact
     6481 cactagcagt gatgtagcat acatttttag gagttttttc ttttgttgct actgaatcag
     6541 tcacaagaat ttctttaata ttagtattgt caagaagctc agcagctccc tcgacgaaga
     6601 gaccgtggct agaaacagca taaatttctg tagctccttc acgttcaacg attttagaag
     6661 cttcagagaa ggtacgtcct gtatttaaaa tatcatcaat caagatagct ttcttacctt
     6721 caacatcacc aataatataa ccttcgttac gagttgcatc gtcttgaggg tagtcgataa
     6781 tggcgatagg agcatcaaga tattcagcca ggctacgcgc acgtttgaca cctgaatttt
     6841 tagggctaac gacaacaaca tctgaaccaa gcaatccttt atcgcagtaa tgttttgcga
     6901 ataggggaac agtgaaaaga ttatccactg gaatatcaaa gaaaccttga acctgaacgg
     6961 catgcaaatc aagagtcagg atacgatcaa ctccagcctt aaccagcata ttggcaacta
     7021 gttttgctgt aagtggctca cgaggacaag caatgcggtc ttgacgtgca tagccaaaat
     7081 atggaaggac aacgttgata ctgtgggcac ttgcacgcac acaagcatcg accatgatta
     7141 acaattccat taggtggttg ttgacaggga aacttgttga ttggatgatg taaacatcat
     7201 aaccacggac actttcttcg atatttactt ggatttctcc gtctgaaaat tgacgtgatg
     7261 atagttttcc aagtgggaca ccaacagctt gggcaatttt ttgtgcaatc tcttggttag
     7321 agttgagtgc gaaaagtttc atgttttttc tatctgacat tatagaccgt cctctgtaaa
     7381 ctttataaat cctagttata tttaccttac atatatgaac tgggatttgt gtatttttat
     7441 cttttctatt ttaccaaaaa atggagatta tttcagctat ttttcatact tttgacaaat
     7501 cgaaccaatt ttgaaggagc tttttggtag gaaatctgat ttttctctaa aaattgtcgg
     7561 aaatcctgtt tgccttgctc atgattttcc acttcaagct ccaattcgta atctgttata
     7621 tcaaagtatc ggctctgatc cagtgccatg agaccaatag ctgttttcat ttcatagcga
     7681 agcgttgtta gacaaccaag aacctgccag ttcttacttt ggataccatg tttcgccaat
     7741 tcatccagta ctagtccttg aggaagttct tccttactca gatagtcctc agcatctttt
     7801 agttgcaatt tttggttgta ttccatgttt ccaacactct gcgggacttt gagtgtcaac
     7861 tcagcccagt cttcaaaggt tcgaatgcgc atagcgactt tcttttctcg cagttcaaaa
     7921 tcaggcgtgt cgatgtagta atttgtttga agaacaggag tgacacctgt gaactggtct
     7981 tttagacgat tgtattcatc ttttttcaat agtgttttca attcaatttc taaatgtttc
     8041 atttttctta ccttttttta tcgttgaaag cggatttatg gtataataag cattgtattt
     8101 attgtatatg aatctggaga aaaaatcaaa gatatttttg acggataata tgagaacaag
     8161 ggagaatata tgaccttaga atgggaagaa tttctagatc cttacattca agctgttggt
     8221 gagttaaaga ttaaacttcg tggtattcgt aagcaatatc gtaagcaaaa taagcattct
     8281 ccaattgagt ttgtgaccgg tcgagtcaag ccaattgaga gcatcaaaga aaaaatggct
     8341 cgtcgtggca ttacttatgc gaccttggaa cacgatttgc aggatattgc tggcttacgt
     8401 gtgatggttc agtttgtaga tgacgtcaag gaagtagtgg atattttgca caagcgtcag
     8461 gatatgcgaa tcatacagga gcgagattac attactcata gaaaagcatc aggctatcgt
     8521 tcctatcatg tggtagtaga atatacggtt gataccatca atggagctaa gactattttg
     8581 gcagaaattc aaattcgtac tttggccatg aatttctggg caacgataga acattctctc
     8641 aactacaagt accaagggga tttcccagat gagattaaga agcgactgga aattacagct
     8701 agaatcgccc atcagttgga tgaagaaatg ggtgaaattc gtgatgatat ccaagaagcc
     8761 caggcacttt ttgatccttt gagtagaaaa ttaaatgacg gtgtaggaaa cagtgacgat
     8821 acagatgaag aatacaggta aacgaattga tctgatagcc aatagaaaac cgcagagtca
     8881 aagggttttg tatgaattgc gagatcgttt gaagagaaat cagtttatac tcaatgatac
     8941 caatccggat attgtcattt ccattggcgg ggatggtatg ctcttgtcgg cctttcataa
     9001 gtacgaaaat cagcttgaca aggtccgctt tatcggtctt catactggac atttgggctt
     9061 ctatacagat tatcgtgatt ttgagttgga caagctagtg actaatttgc agctagatac
     9121 tggggcaagg gtttcttacc ctgttctgaa tgtgaaggtc tttcttgaaa atggtgaagt
     9181 taagattttc agagcactca acgaagccag catccgcagg tctgatcgaa ccatggtggc
     9241 agatattgta ataaatggtg ttccctttga acgttttcgt ggagacgggc taacagtttc
     9301 gacaccgact ggtagtactg cctataacaa gtctcttggc ggtgctgttt tacaccctac
     9361 cattgaagct ttgcaattaa cggaaattgc cagccttaat aatcgtgttt atcgaacact
     9421 gggctcttcc attattgtgc ctaagaagga taagattgaa cttattccaa caagaaacga
     9481 ttatcatact atttcggttg acaatagcgt ttattctttc cgtaatattg agcgtattga
     9541 gtatcaaatc gaccatcata agattcactt tgtcgcgact cctagccata ccagtttctg
     9601 gaaccgtgtt aaggatgcct ttatcggtga ggtggatgaa tgaggtttga atttatcgca
     9661 gatgaacatg tcaaggttaa gaccttttta aaaaagcacg aggtttctaa gggattgctg
     9721 gctaagatta agtttcgagg tggagctatt ctggtcaata atcaaccgca aaatgcaacg
     9781 tatctattgg acgttggaga ctacgttacc attgacattc ccgctgagga aggctttgaa
     9841 accttggagg ctattgagca tccattagat attctctatg aggatgacca ctttctagtc
     9901 ttgaataaac cctatggagt ggcttctatt cctagtgtca atcactctaa caccattgcc
     9961 aattttatca agggttacta tgtcaagcaa aattatgaaa atcagcaggt tcacattgtt
    10021 accagactag atagggacac ttctggcttg atgctctttg ccaagcacgg ttatgcccat
    10081 gcacgattag acaagcagtt gcagaagaaa tctatcgaga aacgctactt tgctttggtt
    10141 aagggagatg gacatttgga gccagaaggg gaaattattg ctccgattgc gcgtgatgaa
    10201 gattccatta ttaccagacg agtggctaaa ggcggaaagt atgcccatac ttcatacaag
    10261 attgtagctt cttatggaaa tattcacttg gtctatattc acctgcacac tggtcgaacc
    10321 catcaaatcc gagtccattt ttctcatatc ggttttcctt tgctgggaga tgatttgtat
    10381 ggtggtagtc tggaagatgg tattcaacgt caggctctgc attgccatta cctatccttt
    10441 tatcatccat ttttagagca agacttgcag ttagaaagtc ccttgccgga tgatttcagt
    10501 aaccttatta cccagttatc aactaatact ctataaaaac tgtctcagag tataattatt
    10561 atcttaaagg agaaaactca tggaagtttt tgaaagtctc aaagccaacc ttgttggtaa
    10621 aaatgctcgt atcgttctcc ctgaagggga agagcctcgt attcttcaag caacaaaacg
    10681 cttagtaaaa gaaacagaag tgattcctgt tttgcttgga aatcctgaaa aaattaaaat
    10741 ttatcttgaa attgaaggaa tcatggatgg ttatgaggtc atcgaccctc aacattatcc
    10801 tcaatttgaa gaaatggttt ctgccttggt ggagcgtcgc aagggcaaaa tgactgaaga
    10861 agatgtacgc aaggttttgg ttgaagatgt caactacttt ggtgtgatgt tggtttactt
    10921 gggcttggtt gatggaatgg tgtcaggagc gattcactca acagcttcaa cagttcgtcc
    10981 agctctacaa atcatcaaaa ctcgtccaaa tgtaactcgt acttcaggag ccttcctcat
    11041 ggttcgtggt acggaacgtt acctatttgg agactgtgcc attaacatca atccagatgc
    11101 agaagccttg gctgaaattg ccatcaactc agcaatcaca gctaagatgt ttggcatcga
    11161 acctaaaatt gccatgttga gctattctac taaaggttca gggtttggtg aaagcgttga
    11221 taaggtcgtt gaagcaacta aaattgctca cgacttgcgt cctgaccttg aaatcgatgg
    11281 tgagttgcaa tttgatgcag cctttgttcc tgaaactgca gctctgaaag ctcctggaag
    11341 tacggtagct ggtcaagcaa atgtcttcat cttcccaggt atcgaggccg gaaatatcgg
    11401 ttacaagatg gctgaacgcc tgggtggctt tgcggctgta ggacctgttt tgcaaggttt
    11461 aaacaagcca gttaatgatc tttctcgtgg atgtaatgca gatgatgttt acaagttgac
    11521 cctcatcaca gcagctcaag cagttcatca atagtgaaaa ctataaagcg atatactatg
    11581 ctatactgta gttatgaaac tatgtacgaa aagcactgcc attaattcct gagaactaaa
    11641 ttactgattg gtgtcaaaaa ggaaaacttc caagcgatga tatcctgtct atacacgacc
    11701 tatagaaatc tgtaatatgt atgtccgtaa aacgataatt tccctttttg attttaaatg
    11761 agtatgaaaa gagaattttt tcatgagaaa acgcataata ttaagtgtct tgacacctgc
    11821 tattatgcgt tttctggctc tttgtcaact gtagtgggtt gaagaaaagc taagctcgag
    11881 aaaggacaaa ttttgtcctt tcttttttga tattcagagc ggtaaaaatc cgttttttga
    11941 agttttcaaa gttccgaaaa ccaaaggcat tgcgcttgat aagtttgatg agattattgg
    12001 tcgcttccaa tttggcgttt gaatagggta gttgaagggc gttgacgatt ttctctttgt
    12061 cctttagaaa ggttttaaag acagtctgaa aaagaggatg aacctgcttt agattgtcct
    12121 caatgagtcc gaaaaatttc tccggttcct tattctgaaa gtgaaacagc aagagttgat
    12181 agagctgata gtgatgtttc aagtcttgtg aatagctcaa aagcttgtct aaaatctctt
    12241 tattggttaa atgcatacga aaagtaggac gataaaatcg cttatcactc agtttacggc
    12301 tatcctgttg aatgagtttc cagtagcgct tgatagcctt gtattcatgg gatttcggat
    12361 gatggcttgt gttctgctct caagaacagt tatgatattg agcttatcaa agtcctgagc
    12421 aataaagctc atctccatct cccgattgaa acagtcactc cccggactgt ttcaacgtcc
    12481 caagacataa tctcaggaag acgcgaaaaa tcatgct
//
LOCUS       DAVBEM010000057        11768 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVBEM010000057 DAVBEM010000000
VERSION     DAVBEM010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11768
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.057"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            1..1042
                     /locus_tag="VQ548_001795"
                     /pseudo
     CDS             1..1042
                     /locus_tag="VQ548_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1158..1961)
                     /locus_tag="VQ548_001796"
     CDS             complement(1158..1961)
                     /locus_tag="VQ548_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HET2654599.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(2240..2995)
                     /locus_tag="VQ548_001797"
     CDS             complement(2240..2995)
                     /locus_tag="VQ548_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HET2654600.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(3065..5716)
                     /locus_tag="VQ548_001798"
     CDS             complement(3065..5716)
                     /locus_tag="VQ548_001798"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HET2654601.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYSTTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPKFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTDDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGEIYVGEEAPAGDGWKQDEDVLDTWFSS
                     ALWPFSTMGWPNTETTDFKRYYPNSTLVTGYDIIPFWVSRMIFQGIEFTGKSPFKNAL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIDKYGTDSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAEYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(5709..6287)
                     /locus_tag="VQ548_001799"
     CDS             complement(5709..6287)
                     /locus_tag="VQ548_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET2654602.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYQLMYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(6287..6757)
                     /locus_tag="VQ548_001800"
     CDS             complement(6287..6757)
                     /locus_tag="VQ548_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2654603.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGYG
                     IVVKGTDKIVGSVDFNHRHEDDVLEIGYTLHPDYWGRGYVPEAARALIDLAFKDLGLH
                     KIELTCFGYNLQSQRVAEKLGFTLEARIRDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            complement(6744..7322)
                     /locus_tag="VQ548_001801"
     CDS             complement(6744..7322)
                     /locus_tag="VQ548_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HET2654604.1"
                     /translation="MKQSFKTNKLYYGFPVFILGYQDQNFGYNITTCSSSYSLGDWVV
                     IGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEKLERLGVHYEISERTQ
                     TPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDEKGHFKNQLFAPTYFM
                     GDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(7605..8000)
                     /locus_tag="VQ548_001802"
     CDS             complement(7605..8000)
                     /locus_tag="VQ548_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET2654605.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(8096..8350)
                     /locus_tag="VQ548_001803"
     CDS             complement(8096..8350)
                     /locus_tag="VQ548_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HET2654606.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(8359..9693)
                     /locus_tag="VQ548_001804"
     CDS             complement(8359..9693)
                     /locus_tag="VQ548_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HET2654607.1"
                     /translation="MTDEWIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVLDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYELMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTVKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKRLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(9693..9926)
                     /locus_tag="VQ548_001805"
     CDS             complement(9693..9926)
                     /locus_tag="VQ548_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HET2654608.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLTGTPMDKIVRTLEANGYEVIGLD"
     gene            complement(10195..10335)
                     /locus_tag="VQ548_001806"
     CDS             complement(10195..10335)
                     /locus_tag="VQ548_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654609.1"
                     /translation="MKFFWTILAILFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(10332..10514)
                     /locus_tag="VQ548_001807"
     CDS             complement(10332..10514)
                     /locus_tag="VQ548_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654610.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKDDHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(10516..11299)
                     /locus_tag="VQ548_001808"
                     /pseudo
     CDS             complement(10516..11299)
                     /locus_tag="VQ548_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3519 a         2558 c         2176 g         3515 t
ORIGIN      
        1 aggctggact aaagatagag tttctcttga atactgcctc ccaagtcgta cgatacttct
       61 taactggcta gcacaataca ggaaaaacgg gtatactatt gttgagaaaa caagagagag
      121 agtacctgag agcggagaat gccatcctaa aaaagttaag agaactccga ttgaaggagg
      181 aaaaagagaa agaagaaaga cagaaattgt tcaagaatta atgactgagt tttcgttaga
      241 tcttcttcta aaagccatta aactagctcg ttggacctac tactatcact tgaaacagct
      301 agacaaaaca gataaggacc aagagcttaa agctgaaatt caatccattt ttatcgaaca
      361 caagggaaat tatgcttatc gctgtgttca tttagaacta agaaatcgtg gttatctggt
      421 aaatcataaa agagttcaag gcttgatgaa agtactcaat ttacaagcta aaatgcgaca
      481 gaaacgaaaa taaaggagac gttggtaaga aggcagagaa tctcattcaa ggccaatttg
      541 aaggatctaa aacaatggaa aagtgctaca cagatgtgac tgaatttgcc attccagcaa
      601 gtactcaaaa gctttactta tcaccagttt tagatggctt taacagcgaa attatcgcct
      661 ataatctttc aacttcaccc aacttagaac aagtacaaac aatgttggaa caggcattca
      721 cagagaagca ctacgagaat acgattctcc atagtgacca aggctggcaa taccgacacg
      781 attcttatca tcggttccta agagtaaggg aattcaagca tctatgtcac gcaagggaaa
      841 cagccaagac aacggtatga tggagtcctt ctttgggatt ctgaaatcgg aaatgtttta
      901 cggttatgag aagtcgtttc agtcgcttaa gcaattggaa caagccatta tagactatat
      961 tgattactac aacaataaac gaattaaggt aaaactaaaa ggacttagcc ttgtgcaata
     1021 cagaactaaa tccttcggat aaattatttg tctaactttt tggggtcagt acacctaaaa
     1081 ctttgatgat atacgttttc ttgtgagaat atttacttca tttttgccta aaattcaatg
     1141 tttactcagt atttggatta tgaaaaatcg aggtctaaat ctagatacat tttttctgaa
     1201 gacaaatcat tttgaccacc gagcaagaga ttttcaaaaa aagctgttaa aaactcagaa
     1261 cgtcgctgta aaatctttgc attatctaat accaaggcat cacgaaaata tttggaatgt
     1321 tgctgaaatg gtgtattatc aatatcaaaa ccaaactcac gaagatactg aatcaaaaag
     1381 accgttactg tccgagtgtt tccttcgcga aatggatgaa tctgccagat tcctgaaata
     1441 aaatgctgga tttgtttaac cacatccgcc tgagttagtg tcgcatatgc aacttgtttt
     1501 tcctgattaa aatcataatc taaggtcatt tgaatcatgg agtaatcaga gtacacaaca
     1561 ctttcaccat tcaaaacagg ttcattcttt gtgatattgg tctgacgaaa ttgccccacc
     1621 ggaatagagg gttcaaatat atcttgaaac aactccttat gaatagcaag taaggtcgca
     1681 ggactaaagc taaagcctct tcgagacaat agttctacaa tacgtagaga aaccaagtct
     1741 gcctcttccg tacttgcatc aatagtatgg tgataagccg ttgcatcctc ataaacctgc
     1801 tcataagtca gttctccccg ggactgtttc tcagccaaag attccatata cgctgatggc
     1861 actagattgt caactttctg cagaccaaaa cctatccgcc ataaatcacg cttcgcttca
     1921 taagacaagt ttggattgtc aatgttgtaa gttgattgca tagaaatatc ctttcaattg
     1981 tttttcttca ttaccagtaa atcacgaaat tggttggaaa ctggcttaaa ctataaaaag
     2041 tcctcacaat aggttctatg atatatatat atatacttca tgtaaataat aaaagagtta
     2101 taatcagcac tactgataaa ttcaataccg atttcgccat cttaaaactt agtcaaacga
     2161 ataccgttga tttccagttc attaagtcgt tgacctgtca agacttctcg ttccttcaac
     2221 tggaaaagtt aagggggaac taatacaaat cctctacgct tctatattca atgatttcat
     2281 ttttgataat attcttttta aactcaaaat gttttaaagg attatcgatt aacactaact
     2341 ttggaatatc atctagattt gtgaccaagg ataaaataaa atccgattga aactccttga
     2401 ctttttcaaa ttcttttgca gttaaacgca cacgcccctt agattttcgg atacctttta
     2461 cttcggcaag gtaagaatac tcttggacat ctacctgaaa gtcatatcca tcaccataaa
     2521 gacgggcatc ggttaactgt ccaccttgga atttttcttc tttatcaaaa tgaaggataa
     2581 aataattctc agcctccatt cccgtttcct gtagacgttt gaatttagtt cgaactattg
     2641 gtttttcaac gatggttatg cctgttttct tcccttcact ggcaagtaac attttaacta
     2701 tttcagcata actatgaaca tcttcatttc caaacatcat atcaattaaa tctttacgaa
     2761 aacgataaac ttcagctttc tgccaccaac cttttcgatt attgtcaaaa taaggatcaa
     2821 ataaatccat tctatttttt acaactccag ttgtttcagc aattcccaga gaaaccacat
     2881 agcgataaaa ctccgacttg ctagagcatt gaaattcttt tataaaaagc ttgtcaaact
     2941 tggcaagacc gtagccaatt aaatttaaca attcataatg agggtgtttg gacatcactt
     3001 tctccatcaa tagatattga tttcattata ccaaaaaaca cggctcatca ccgtgtttct
     3061 gtgtttattt caccaacttc ttcatctcat caatacgtgc tacggtcgca tcatacttag
     3121 cttggtaatc tgcttgcttg tcgcgttctt tttggacaac ttctggttta gcgttggcga
     3181 cgaagcgttc gttgctgagt tttttgccaa ccatgtcgag ttctttctgc catttggcaa
     3241 gttctttttc cagacgtgcc aattcttctt cgacattcaa gaggtctacc agtggcaaga
     3301 agatttcggc tcctgtgatg acgcttgaca tagccagttc aggtgcaggg atggttgatg
     3361 cgatttccaa gtgttcagga tttgtgaaac gtttgatgta gttgacattg ctgttaaaga
     3421 aggcttccaa gtcgctatcg cttgtcttaa caaggatagt gataggcttg cttggagcaa
     3481 cgtttacttc cgcacgcgca ttacgaacgg cacggatcaa gtctttaagg ctttccacac
     3541 cagtgtgagc agcaaggtct tcaaaggctg ggttgacagt tgggtattct gctgtaacga
     3601 tagatccttc tgagatttgt ccaaagattt cctctgtcac aaatggcatg attgggtgaa
     3661 ggagacgaag gatcttgtcc aaagtgtata gtagaacaga acgtgtgatg actttctctt
     3721 cttcgttatc gctataaagg acttccttgg tcaactcaac ataccagttg gcaaattctt
     3781 cccagatgaa gttgtaaagg atatgaccag ccacaccaaa ctcgaactta tcaaagtttt
     3841 cagtaacttt tgcaatggtt tcgttgagat tgtggagaat ccagcggtcc gtcacattac
     3901 cagcctcacc tgttgcaact tttgtgacat tgtcatgcgc cacatccagc gtcaaacctt
     3961 cattgttcat gaggatatag cgagaaatgt tccaaatttt gttaataaag ttccatgaag
     4021 catccatttt ctcgtaagag aaacgaacgt cttgaccagg agctgagccg tttgacaaga
     4081 accaacgaag actatctgta ccatatttat caataacatc cattgggtca atgccatttc
     4141 caagagattt agacatctta cgtccttctt catcacgaat tagaccatgg ataagagcat
     4201 ttttaaatgg gctctttcct gtaaattcaa ttccttggaa aatcatgcgt gatacccaga
     4261 aaggaataat atcatagcct gttacgagtg ttgaatttgg atagtagcgt ttaaagtcag
     4321 tagtttcggt attaggccag cccatggttg agaagggcca gagggcagag ctgaaccaag
     4381 tgtcaaggac atcttcgtcc tgtttccagc catcgcccgc tggggcttcc tcgccgacat
     4441 agatttcgcc tgcttcatta taccaagcag ggatttggtg accccaccag agctgacggg
     4501 aaatcaccca gtcgtggaca ttttccatcc attgcaggaa ggtgtcgttg aagcgcggtg
     4561 ggtaaaattc caccttgtca tctgtgtctt ggttggcaat ggcgttcttg gccaattggt
     4621 ccatcttgac gaaccattga gtagacaagc gtggctcaac tacgacacct gtccgttctg
     4681 agtgaccgac tgaatggaca cgtttttcga ttttgacaag ggcaccgatt tcttccaact
     4741 tagcaacgac tgccttacga gcttcaaaac gatccatgcc tgaaaattca aaggcaagct
     4801 cgttcatagt tccgtcgtcg ttcatgacgt tgacttgtgg caagttatga cgttggccaa
     4861 ccaagaagtc atttggatcg tgggcaggtg tgattttcac gacaccagta ccaaacttag
     4921 gatctgcgtg ctcatcacca acgattggga ttaatttatt agcaattgga aggatgacat
     4981 ttttaccaat caagtccttg tagcgcgggt cttctgggtt gaccgcaacc gcaacgtccc
     5041 caaacatggt ctcaggacga gttgtagcaa cttcaagggc gcgtgaacca tcttccagca
     5101 tgtaattcat gtgatagaag gcaccttcga cgtccttgtg aataacctcg atatcagaaa
     5161 gggctgtgcg agctgctggg tcccagttga tgataaactc accacggtag atccagcctt
     5221 tcttgtaaag gtccacaaag accttacgaa cagcttttga caaaccttcg tcaagagtga
     5281 aacgctcacg agagtagtct acagagagcc ccatcttgcc ccattgttcc ttgatagtag
     5341 tggaatattc gtctttccat tcccagactt tcgtcaagaa agactcacga ccaaggtcat
     5401 agcgggaaat gccctcacca cgcaagcgct cctctacctt agcctgagtg gcaatccctg
     5461 cgtggtccat cccaggaagc caaagggtat caaaaccttg catgcgtttt tgacggatga
     5521 taatatcttg caaagttgta tcccaagcgt gaccaaggtg aagtttacct gtaacgtttg
     5581 gtggtggaat aacgattgaa taaggcttag ccttttgatc gcctgaaggc ttgaaaacat
     5641 cagcatcaag ccatttttgg taacgaccag cctcaacctc ggctggattg tatttagatg
     5701 aaagttcttt agacatgtgt gtgtcctttc tctattttgt ttattttatt ttgaatttgc
     5761 ttagcagctt cttctgcaga caaattcgta ttatttattt taaagtagtg gtgcaactca
     5821 ttcggttgat attgggaatt taattgaagt gtttcagcgg tctctaaaat ttctctttca
     5881 gatacctcaa tatgtcgttt taagggtttg tgctttaatc gattctccgt tcgatttcga
     5941 cgtatgcact cttcaagact tgtttccaac tcaacaaaaa gaatctcttg atgataatca
     6001 tccaacaaat tctgaatttg ctttaaatac atcagttgat actgatttga aaaatcaatt
     6061 acatctgtta aaattactga tcgctgattt cttgcacttg ctccaaggaa tgaaaaagtg
     6121 attccacgaa caaattccca catttcctct gtatagtcct gatagatttc tagtgcaaaa
     6181 tcaatggctt gatggttata aaatagggta gcatccgtca gtcgagataa ttcttgacca
     6241 atggtcattt ttcctgatgc tggagcacca atgatgaaaa gatgcatcaa atcacctccc
     6301 actcactctt cagcaaggca tatctcaaat catcacagca gttgccttga gcatctttac
     6361 ggtctcttat gcgagcttcg agggtaaagc caagcttttc cgcgactcgt tgactttgaa
     6421 ggttatatcc aaagcaagtt agttcaatct tgtgaagacc caaatcttta aaggctaagt
     6481 caatcaaggc acgcgcagct tctggcacat aacctcgccc ccaatagtct gggtgtaagg
     6541 tatagccgat ttccagcaca tcatcttcat ggcgatggtt gaaatcgaca gagccaacga
     6601 tcttatccgt tcctttgacg acaatcccgt agcctgctgg ataggcgacc tctggcaaac
     6661 tagcatagtc aaagatatcc tcagcatccg ccacagtacg gactcgtaaa acgagacgtt
     6721 ctgtttcgat tttatctggc agctcagttc ttgccatcct tcttcctcgc ttttttgatg
     6781 aaactgccct tcatatctac acgcttatcc agatagcgat aaacgcgctg atatccatct
     6841 cccatgaaat aggttggggc aaacagttga tttttaaaat gtcccttttc atccaggagt
     6901 tctggggcaa caagtcgctc aagaatcttg gcaaagatgt ggcaaatacc gtcttcctca
     6961 acaatcctat ctacccgaca atctaaaaca agtggacagg cgtctaaaat aggagtctga
     7021 gttcgttcag aaatttcata atgcactccc aaacgttcca atttctcctg atgactgata
     7081 aaaccagcct gctccatcgc aagcatagaa gtttcatcag aaatattcac agtaaatttt
     7141 tgatactgtt tgatctgctc tgcggcattc tctctcgcaa cgactccaat cacaacccaa
     7201 tctcctagac tatacgagga actacaggtc gtgatgttat agccaaaatt ctgatcttga
     7261 tatcctaaaa taaaaacagg aaaaccataa tatagtttat tagttttaaa tgattgtttt
     7321 ataacaacct cctttgacta agacacaaaa gaaaagccct gccatctaca tgacagggac
     7381 gaatgtattt atccgcggta ccacccaatt tcgggccaag cccgcatctt tagtctttaa
     7441 aataaaaaga cagaaatatt tcattttttc agtcattagc aaccagtttt gacacatttg
     7501 tggacttctc agcgccgcca ctttctgtaa aatgtgggat tcaaaacacc tctaatagct
     7561 ctattgtagc aagtttttct cggaaatgca aggctcaaga aaaattactt gaacttgatg
     7621 ccattttctt tcaatttctt gatggtagct gggccgattc ctttcaaggc aaggagttct
     7681 ttttcagtcc agtttttgaa atctgaagca gacttgattc cttcatcata gaaagtcttg
     7741 gcacgatcaa gtggaagtcc acccaagttt gctgcaaaat cttctacaga attagctact
     7801 ttttgagctt gctctttggt agcttctact gcttgttcaa cttttttaga aacagcctta
     7861 ccagctgcgc ttgctgactg ttctgcacgc ttcacgactt tttttgtctc atctacaacc
     7921 ttagtcacag tacttgaaaa ggcacctgcg cgacggaggc catttcgtaa ttgtttttta
     7981 cgattgagtt tctttgacat gataaaatcc tttcaataaa aaatccctgc tctgacaagg
     8041 atttaacata aacattctat caagatttta gtgaaaaatc aagaatcttt ctcgtttaat
     8101 aatttcgctc accaaacaag ccttctggca aatcatggaa tcccttgcct actttgaagt
     8161 tttcaaactt accaagcaag aactgataag catccaagcg actctcgtag cgaatcatgg
     8221 catctttggc acgctcgtcc tggtcttctt cgtaaacttt ttgactttcc ttgtgcgcca
     8281 tgtcgttaat catgatttgg gtattgaccc aagcttcaaa ttccttcata aattcttgtt
     8341 cgtaactcat ttttctcctt attctaatcc acgaaaatag tccgtatcaa tctcacggta
     8401 gggctggata tcctgaacat actccaacac tccttggaat tctccgtctt catcgtgtac
     8461 tgcagcatag gtgatgtgga caaacttacc tcgcgactca gacttgaacc acatttcata
     8521 cttgtctttg cttccctcac gaagcctctt catgatagtt ttgaccttgt ccaagtactt
     8581 aggcggatgg cagagttcga cattgcgccc gacttgagac ggcgtccgtt tgaaaatcat
     8641 ctcatcagct ggcgtattgt cattgtaata ctggaaaata tcttctttat tgacaaaggt
     8701 aatctccata gggagatgat tgaggatgag attggcctgc tcgactgaaa gatagccatt
     8761 accaaaagcc tgttgactat ggcggtccag cacagcttcc ttttccttag gggtaaaggt
     8821 aatggtaaaa tggccttctg gcgtatctat gacttgttga acttgacctt ctgccgtatc
     8881 tagctgtaca ggctcctctg caatcttttc ctcaataaag ctctgtcgtt ctggcaccca
     8941 tttctctgac ggacggatga tggcatagcc ataggcatcg ctctcctccg caatctgaag
     9001 ccagtcatcc tgagtaaaag actcaaggag aatcatgagg aggatggact cttccttgaa
     9061 aatcatactt tcaaactctg tcgcaaaagc ttcaaaagct tcctttacac tgctaattga
     9121 cacttctggt agtgacttga ctgtcgttag agctgtttga aagagttccc taatctgatc
     9181 atccactccc cacataactt tgggaggtga atcgtgtcca tagcgctcca tgataggaaa
     9241 gaagagttct tccttacgtt ggtaatggat gtcaaattgc cccacaagcc ccatctgacg
     9301 caccaagccc ttgcgcatct ccgcaagcat ttcctcgtct tccatcaact cataggtatc
     9361 taacaatcta cgaatgcgaa tcaaagctgc acggagggcc aaattttctt ccttaaagac
     9421 acgaactggg tgcccagggt gttcggtatc taaaacttcg acacctttga tagcattttt
     9481 aaaaagattg gcatggacat cacagagttc cataacatct tcaaaagtga cgcccgaatc
     9541 cgagttcatc agctcgtgct ccataaggga aatctcgatg gctgacacgc ccgtaaaggt
     9601 cgcatcaaag cgatcttgaa ccgactcagg agaggcgcca ttgtgcaatt ctaacaaaat
     9661 atcccgtagg atatgaatcc attcatctgt cattagtcta atccaatcac ttcgtagcca
     9721 ttcgcttcca gtgtgcgtac aatcttgtcc ataggagttc ctgttagctt agaaccctgt
     9781 ttaagtgata ctttacgacc aactgtattg cgcattaagg gattggcaag gggtttaaaa
     9841 cccaactcca ctagaatttc caagacttct ggatgcttgt ccaccacttc tgcaacagga
     9901 attgacacat cgatgatatt gtccatgacg acctccattg tatgttctaa tactcaatga
     9961 aaatcaaaga gcaaactagg aagctagccg caggttgctc aaaacagtgt tttgaggttg
    10021 tggatagaac tgacgaagtc agtaaccata cctacagcaa ggtgaagctg acgtggtttg
    10081 aagagatttt cgaagagtat aaaatgattt tactgcttat attataccat atggagagag
    10141 attaaaaaac tagcagtgga gttcctgcta gttttctgcg acttggatta ccatctagat
    10201 aagtttaaag aaccaatcca atatcttgta aaacagcaat tgaactgcaa aagaaatgat
    10261 catccaaaag aatttcacaa tcccaataat cggtttgata aaaagaatag caagaattgt
    10321 ccagaaaaat ttcattctct ctcctctggc ttaatgagcc accgagccgt atccattagc
    10381 ttatctgcaa taaagagttt tcccagacca acaacgacat ggtcatcttt ctttatcgtt
    10441 ttcatcactt ttacaccttg cacggtcaaa aagtaattac cataaatttt agcaaaagct
    10501 ttgataggat tcatattatt ctcctttgat gatttcagcc tcttttcgga ttgtttcaac
    10561 atcttcttga tattgaactt cactatagtt gactagcttg gataattctt tctgcaagct
    10621 ttcccccatt ggtttcatag ttgcaaaggt taaaccacct gaaatgatac cacccaagat
    10681 aggaataaat ttccccattc ctttggccaa ccctcccttg gtaagattca caccaaatat
    10741 ttttaagact tttttcaaaa tagggtacca aagcgtcttt gttaaagctt tattaggcac
    10801 tgttttcatt acctgtttgg caattgttat accaccagca cgtagcaaac aaagcagcgg
    10861 ttccattcac ccctaacatt acgcctagat aaagcaagag ggtattttga gcatcttcac
    10921 tcaactcctc acgtgaagcc caaagatcct cataaccata aatataacct aattcttggg
    10981 ccaatttcag agagaaacca taaaattgag ccacataagc tggaatggta attgccatag
    11041 caagccctcc aggtaatcct gccaaaacag aagtcccact cgctaataaa acattatccc
    11101 taatacaggc attagccact cgatctaaga tttcttgaga taagagagac gttggacctt
    11161 gttccaataa ggtaggaatg tcctgtggac ccaattcttt ggaaaactta tccactaaaa
    11221 atttcgaacg atcaacctta acaactggta gttttaccac ttgttgtaat acttgcatag
    11281 ctaagtcttg ttcagccata tacaaactcc ttatttcttt tttgcacctt atcatattat
    11341 atttcctaca aaaaaagcat tttctaatta gataacatta aaaaatacag aacccctttt
    11401 ttatagtaaa ataaaacaag aacaggacaa atcgatcagg acagtcaaat cgatttctaa
    11461 caatgtttta gaagtagagg cgtactattc tagtttcaat atattttaaa agaatatttt
    11521 tccatttcaa attcaaccta ttttcctcca ccaaaaaagg gctctataat atttgtagtg
    11581 ggtaaattcc ctatggatat tatggagcct atttttgtgt agaaaaaaag tcccatatga
    11641 cctataatga aaagcgacaa aacaactcat tagaaagaat catatggaac aattacattt
    11701 tatcacaaaa ctgctcgata ttaaagaccc aaacatcaag attctagata tcatcaataa
    11761 agatacac
//
LOCUS       DAVBEM010000058        11762 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVBEM010000058 DAVBEM010000000
VERSION     DAVBEM010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11762
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.058"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            <1..209
                     /locus_tag="VQ548_001809"
     CDS             <1..209
                     /locus_tag="VQ548_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2654611.1"
                     /translation="RKSSKLKPLTVEDKACNHALSKERSKVENIFAKVKTFKMFSTTY
                     RNHRKRFGLRMNLSAGIINHELGF"
     gene            359..613
                     /gene="blpM"
                     /locus_tag="VQ548_001810"
     CDS             359..613
                     /gene="blpM"
                     /locus_tag="VQ548_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HET2654612.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            629..832
                     /gene="blpN"
                     /locus_tag="VQ548_001811"
     CDS             629..832
                     /gene="blpN"
                     /locus_tag="VQ548_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HET2654613.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            1076..1225
                     /gene="blpO"
                     /locus_tag="VQ548_001812"
     CDS             1076..1225
                     /gene="blpO"
                     /locus_tag="VQ548_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HET2654614.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            1329..1448
                     /locus_tag="VQ548_001813"
     CDS             1329..1448
                     /locus_tag="VQ548_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET2654615.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            2234..2632
                     /locus_tag="VQ548_001814"
     CDS             2234..2632
                     /locus_tag="VQ548_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET2654616.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEVGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKKQTVFLILQQ"
     gene            2670..3359
                     /locus_tag="VQ548_001815"
     CDS             2670..3359
                     /locus_tag="VQ548_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2654617.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNFV
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            3401..3649
                     /locus_tag="VQ548_001816"
     CDS             3401..3649
                     /locus_tag="VQ548_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654618.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLKWFVLERLELKDDA"
     gene            3679..4290
                     /locus_tag="VQ548_001817"
     CDS             3679..4290
                     /locus_tag="VQ548_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2654619.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            4451..5245
                     /locus_tag="VQ548_001818"
     CDS             4451..5245
                     /locus_tag="VQ548_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HET2654620.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5242..5877
                     /gene="trmB"
                     /locus_tag="VQ548_001819"
     CDS             5242..5877
                     /gene="trmB"
                     /locus_tag="VQ548_001819"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HET2654621.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            6003..6482
                     /gene="rimP"
                     /locus_tag="VQ548_001820"
     CDS             6003..6482
                     /gene="rimP"
                     /locus_tag="VQ548_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HET2654622.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            6526..7662
                     /gene="nusA"
                     /locus_tag="VQ548_001821"
     CDS             6526..7662
                     /gene="nusA"
                     /locus_tag="VQ548_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HET2654623.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            7684..7977
                     /locus_tag="VQ548_001822"
     CDS             7684..7977
                     /locus_tag="VQ548_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HET2654624.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            7970..8269
                     /locus_tag="VQ548_001823"
     CDS             7970..8269
                     /locus_tag="VQ548_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HET2654625.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8286..11078
                     /gene="infB"
                     /locus_tag="VQ548_001824"
     CDS             8286..11078
                     /gene="infB"
                     /locus_tag="VQ548_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HET2654626.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            11329..11679
                     /gene="rbfA"
                     /locus_tag="VQ548_001825"
     CDS             11329..11679
                     /gene="rbfA"
                     /locus_tag="VQ548_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HET2654627.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         3608 a         2061 c         2670 g         3423 t
ORIGIN      
        1 cacgtaaatc cagcaaactc aaaccgctaa cagttgaaga taaagcctgt aaccatgcgc
       61 tatctaagga gagaagcaag gttgagaaca tctttgccaa agtaaaaacg tttaaaatgt
      121 tttcaacaac ctatcgaaat catcgtaaac gcttcggatt acgaatgaat ttgagtgctg
      181 gtattatcaa tcatgaacta ggattctagt tttgcaggaa gtctaatgta atttttgcaa
      241 ttcaagacgt ttcgatgact attcaagatc tggatgaaaa attttaaaaa acgatgatat
      301 actaaacttg tcaaagttac aacaagacaa aaattaaaaa taaaaaagag tatttgtcat
      361 ggatacaaaa attatggaac aatttcatga aatggatata actatgttat ctagtattga
      421 aggaggcaag aataattggc aaactaatgt cttggaaggt ggtggtgctg cttttggtgg
      481 ctgggggcta gggacagcta tttgtgctgc gagtggtgtt ggagcaccat ttatgggagc
      541 atgtggatac ataggagcta aatttggtgt ggatctttgg gcaggagtaa caggggcaac
      601 gggtggattt taataaaagg agacttgtat gaatacttat tgtaatataa atgaaacaat
      661 gctgagtgag gtttatggag gtaattccgg aggagcagct gtagttgctg ctttaggttg
      721 tgcagcgggt ggagtgaaat atgggagact tctaggacca tggggcgctg caataggagg
      781 aattggagga gcagtggttt gtggatattt agcctatacc gctacatcat aaaaatgaaa
      841 gctaaatttt atgaaggcta tattctttat tattctcttc gcttttcaaa cctatcttat
      901 ttatctatcc ataagtatct ccgataaaaa acaaaagact attgaattaa catcattgaa
      961 ttgttttgtc atattatttc taatctatga taaattaatt tttctcttta ttgcctatgt
     1021 ttttttgata atttttatat taaacttgtt ccgtaactga aaagtgatat actatatgga
     1081 tacaaaaatg atgtcacaat ttgcagttat ggataatgaa atgcttgctt gcgttgaagg
     1141 tggagatatt gattggggaa gaaaaattag ttgtgcagca ggggttgcat atggcgcaat
     1201 tgatgggtgt gcaacaacgg tttgacattt ctattgggac catttgctat aggaataggt
     1261 gtaactggtg ctgcaggtgg agctatactt ggaggtgtag cctatgcagc aatatgttgg
     1321 tggtaattat ggattttaaa agttttatta ttggtttagt agttggtata tttggtcctt
     1381 atatggatga cttaattaga aaaatatttt caaaatcttc caaaaaggat acggatagta
     1441 ctctctaaaa aataaatttc tcccctgtat ttgctagctt aatttacagg ggagtttctt
     1501 taatattgtt tcgcctgtca aaatgatatg tgatagcagg atgaaaagtc tacaaacaag
     1561 ttggtatcaa tacaatataa agaggaaagt atgtttttaa tgcttacttt ttaaattttt
     1621 taacaattca agatgtttcg atgacaattc aagatttgga tgaaaaattt taaaaaacaa
     1681 tgatatacta aacttgtcaa agttgcaacg ggtgctgcta cattatgtta aaaatcgctc
     1741 ttgattgata agctggattt gttaggaaag gagtaaataa ttatggataa gaaaaagata
     1801 gtttcgacta taatatgtat agtatttctt gtagtgtcag tagataattt ttttagagac
     1861 ttaaccccgt tactgttcat tttaaatatt attggcctgt cttgcttttc agtgctaaca
     1921 tacattaaca taaaagagat actcttaaat ataagtaaat gatgatttgg ttagtcctag
     1981 aaccaatcaa cttatgttta tcggcttggc agattttatg tttgtcattt gtttgtatag
     2041 aggtatttca gaaacagaat tctatcaaca actaatcgct tatataggtg tattctctgc
     2101 ttgtttatca cgcttctgct catgtggggc ttgaagtatt ataaaaagta gctttctatc
     2161 cttttctgac aggatatttg agtagaaggc tctattaaat tgttagtgaa ataaatgaat
     2221 ggaggtattt aatatgaaat acagattatt ttttgttatt ttcttgagta gtgtgttgga
     2281 tattctttta gggacatttt tacaaatctc tatcgtatct attgggtggc ttgttcttta
     2341 cagtggtttg tttgaagtag gagttttcct tcttgctaat aaaggggtgg cggtaaaaat
     2401 caaggaagta gatattcgaa atcgctttaa atttattttt ggaaaaacct tatggtttca
     2461 aattcttttg ctcatctttt tgataatcaa actttatctt ggtttggatg cgaggttgat
     2521 tttattctat ggacatattt tcattgtctt taatgcctta atgtatctat tatctagtag
     2581 tcaggttagc cttaaaaaaa aacaaactgt cttcttaatc ttacagcagt agagtctgac
     2641 aaggtgaggt catagtaggg aggatttcta tgaaaaagta tcaacttcta ttcaaaataa
     2701 gtgcagtctt ctcttactta tttttcgtat ttggtctttc tcagctgacg cttatcgtcc
     2761 aaaattattg gcaattttct tcccagattg gtaatttcgt ctggattcaa aatatcttga
     2821 gtttactttt tattggagtc atgattgtgg ttcttgttaa gacaggccat ggttatctct
     2881 tccgcattcc aagaaaaaaa tggctttggt attcgatttt gacagtatta gtggtagtgt
     2941 tccagatctc ttttaacgtt cagacagcta aacatgttca gtcaactgcg gaaggttggg
     3001 ctgtattgat tggttatagt gggactaact ttgcagagct aggtatttat atagccctgt
     3061 tctttctggt tccactgatg gaagaattga tttatagagg attactgcaa catgctttct
     3121 ttaagcattc gcgatttggt cttgatttgc ttcttccttc tattttattt gctctccctc
     3181 atttttcaag cctgcctagt ctgttagata tcttcgtctt tgcaacagtt ggaatcatct
     3241 ttgctggttt gacccgctat accaagagca tttatccatc ctatgcggtg catgtgatca
     3301 ataatattgt agcgaccttc ccgtttttgc tcacttttct acatagggtc ttggggtaaa
     3361 aaaacaaaag gcttgctttt cagccataga ggaggtcatc atgtataaac acttattttt
     3421 cctagattcc aaaactttag atcggttgac accctatatt ctagtcttgg cttctgacac
     3481 cattgctttt aatgtttttg tgctaacctt tgtatctgcg gtggttttta atttcctaaa
     3541 ttccatgcta gctttaatgg ctatattcat aggggctggc tatgtggtcg gattttggtt
     3601 gctaaaatgg tttgttttgg aaaggttaga gctaaaggat gacgcgtagg aagtctgttt
     3661 ggtgaggagg atagttttat ggagtttttt gataaatttc atgccttgtg ttttggattt
     3721 ttagtactaa taattgtcat tacagttcct tatacgatta accatggggg tttttttcaa
     3781 aatgaatctg cattgattct tgtaagtctt cttgtaacct cgctgagtgt tgcttatgct
     3841 agaaagtttg aaatgatttc ttttgggatg ttaagcaaga aacaactttt gcttttcatt
     3901 gcaatctttc ttctaagtgt acttgagacg ctggtttata ttcatttctt cgctgtttct
     3961 tctggctcag gggtccaaca cttggcggaa gtcagcagag gaatttccct gtctttgatt
     4021 ttgactacct cagtttttgg ccccatccag gaggaactca ttttcagagg acttcttcaa
     4081 ggtgcggttt ttgacaattc ttggttaggg cttgtgctaa cttcctctct cttttctttc
     4141 atgcatggac cttctaatgt cccttcgttt attttttatc tacttggggg tttgttgctg
     4201 ggctttgctt ataaaaagag tcaaaaccta tgggtttcta ctctagtaca catgttttac
     4261 aacagttggc cactcctata ttatttataa aaattatgaa aaggtaagca gaagacggtg
     4321 cttacctttt tcaagctata atgataccca agccaatcca gaggcttttc tttgagaatc
     4381 gggttagagt ggttgacgaa taggccaaaa actagtagaa tagtaaggaa actttatacg
     4441 gaggaaagaa atggatttgg gtgataatga gctaacactg actcccatac ctgggaaaag
     4501 tggcaaggct tatatgggta gctatcctga cgggaagcgc atctttgtaa aaatgaacac
     4561 ctctccaatc ctacctggtc tagctagaga acaaattgct ccacaattat tatggagtcg
     4621 tcgtttggca gatgggcgtg atatgtgtgc tcaagaatgg ttgacaggca agatattgac
     4681 cccctatgat atgaatcgta agcaaatcgt caatatttta acccgtcttc atcgctcacg
     4741 tccgttgatg acacaattga gtcgtttggg ctatgccatg gaaacacctg tagatttact
     4801 acagtcttgg caggaaacgg ctccagatgc tttgcgtaaa aatcatttta tcagtgaagt
     4861 gatggctgat ttacgtcaga ctattccagg atttagagag gaccatgcga ccattgtcca
     4921 tggagatgta cgacatagta attggattga gacagatagt ggcttgattt atttagtaga
     4981 ttgggattcg gttcgcttga ccgatcgcat gtttgatgtg gcccatatgc tctgccatta
     5041 tatttcagaa catcagtgga aggaatggtt gacctactac ggttacaagt acaatcaaac
     5101 ggtattaagt aaattgtatt ggtatggtca attgtcttat ttgagtcaga tttccaagta
     5161 ttatatgaac caagatttag aaaatgtcaa tcgggagatt catggtttgc gtcatttccg
     5221 agacaagtat ggaaagagaa gatgagagtt agaaatcgta aaggggcaac agaattacta
     5281 gaggcaaatc cccagtatgt ggtcctcaat cccttggaag ccaaggcaaa atggcgggac
     5341 ttgtttggca atgataatcc cattcatgtg gaagttggaa gtggaaaggg tgcctttgtt
     5401 tcaggtatgg ccaagcaaaa ccctgacatc aactatatcg ggattgatat tcaaaagtct
     5461 gttttgagct acgctttgga caaggtgctt gaagttggag tgcctaacat caagctcttg
     5521 tgggtagatg gttctgactt aactgactat tttgaagacg gtgagattga tcgcttgtat
     5581 ctgaactttt cagatccatg gccgaaaaaa cgccatgaaa agcgtcgttt gacctacaag
     5641 accttcttgg ataccttcaa acgtatcttg cctgaaaatg gagaaattca tttcaagacg
     5701 gataaccgtg gcttgtttga gtacagttta gtgagctttt ctcaatatgg catgaaactc
     5761 aatggtgtct ggttagattt gcatgccagt gattttgaag gcaatgtcat gacagaatac
     5821 gagcaaaaat tctcaaacaa ggggcaagtt atctaccgag ttgaggcaga attttaagag
     5881 atagcctaaa attaggctgt acaagtgctt ttgctttaca taagttggca aacgtgctat
     5941 actgatagta agaatatgaa aagtgaggcg gggaaatatc ttcgcctctt gcttatgagg
     6001 aggtggacgc aatcgcaaca atcgtagaat tagtcagaga agttgtagaa cctgtcatag
     6061 aagctccttt tgaactcgtg gatatcgagt atggaaagat tggcagtgac atgattctca
     6121 gtatttttgt agataaaccc gaaggaatta ccttgaacga cacggcagac ttgacagaaa
     6181 ttatcagtcc tgtcctagac accatcaagc cagatccctt cccagaacaa tatttcctag
     6241 aaattaccag tccaggtttg gaacgccctt tgaaaaccaa ggatgccgtc gctggagcgg
     6301 ttggaaaata catccatgtc gggctctacc aagccatcga taagcaaaag gtctttgaag
     6361 gaaccttgtt ggccttcgaa gaggacgagt tgactatgga atatatggac aagacgcgta
     6421 agaaaaccgt ccaaattcca tacagtttag tatcaaaagc acgtttagca gttaaattat
     6481 agaaaaagaa aggatagctt ttgaggattc aaaagtgaag aaaacatgag taaagaaatg
     6541 ctagaggcct tccgcatttt ggaagaagac aagggaatca aaaaagaaga tatcatcgac
     6601 gcagtagtag agtcgcttcg ttccgcttat cgcagacgct atggtcagtc agacagcgta
     6661 gctattgact tcaacgaaaa aacaggtgac tttacagttt atactgtccg tgaagttgtt
     6721 gatgaagtat ttgatagccg tttggaaatc agcttgaaag atgctcttgc cattaattca
     6781 gcttatgaac ttggagacaa aatcaagttt gaagaagcac cagctgagtt tggtcgtgta
     6841 gcagcccagt ctgccaaaca aaccatcatg gaaaaaatgc gcaagcaaac acgtgccatc
     6901 acttacaata cttacaaaga acatgagcaa gaaatcatgt ctggtacagt agaacgcttt
     6961 gacaaccgct ttatctatgt caaccttggt agcatcgaag cccaattgtc aaaacaagac
     7021 caaattcctg gagaagtttt tgcttctcat gatcgtatcg aagtttatgt ttacaaggtt
     7081 gaagacaacc ctcgtggtgt gaacgtcttt gttagccgta gtcatccaga aatgatcaaa
     7141 cgtttaatgg agcaagaaat tccagaagtt tatgatggaa ctgttgaaat catgagcgtg
     7201 gctcgtgaag caggtgaccg tacgaaggtt gctgttcgta gccacaatcc aaacgtggat
     7261 gctatcggta caatcgttgg acgtggtggt gctaatatca agaagattac tagcaaattc
     7321 cacccagctc gttacgatgc taaaaatgac cgcatggtac caatcgaaga aaatatcgat
     7381 gttatcgagt gggtagcaga tccagctgaa tttatctaca atgccatcgc tcctgctgag
     7441 gttgaccaag ttatctttga tgaaaacgac agcaaacgtg ccttggtggt tgttccagat
     7501 aacaagcttt ctcttgccat tggtcgtcgt ggacaaaacg tgcgcttggc ggctcacttg
     7561 actggttacc gtatcgatat caagtctgct agcgaatttg aagccatgga agacgctgct
     7621 tcagtagagt tggaagtaga aaacgatact gtagaagaat aaaagctgct agaggaggga
     7681 aagatgaaaa caagaaaaat ccctttgcgc aagtctgttg tgtctaacga agtcattgat
     7741 aagcgtgatt tgctccgcat tgtcaagaac aaggaaggac aagtctttat tgatcctacg
     7801 ggcaaggcca atggccgcgg cgcttatatc aaactagaca atgcagaagc cctagaggcg
     7861 aaaaagaaga aggtctttaa ccgcagcttt agcatggaag tggaagaaag cttttatgac
     7921 gagttgatcg cttatgtgga tcacaaagtg aaaagaagag agttgggact tgaataagca
     7981 aaagataagt aatctcttgg ggcttgctca gcgagcaggg cgcatcatat cgggtgaaga
     8041 attggtggtc aaggccattc aagacggcaa ggccaagttg gtctttctag ctcatgatgc
     8101 tggacccaat ctgaccaaga agattcaaga taaaagtcat tattatcaag tagaaattgt
     8161 aaccgtgttt tcaacactgg aattaagcat agcagtcggg aaatcgagaa aggttttggc
     8221 tgtaacagat gctggattta caaagaaaat gaggtctctt atggaataga agaggaggac
     8281 atgatttgtc taagaaaaga ttgtacgaaa tcgcaaaaga acttggaaaa gaaagtaaag
     8341 aagttgtagc gcgtgcaaaa gagttgggct tggatgtgaa aagccactca tcaagtgtgg
     8401 aagaagctgt cgctgcaaaa attgctgcca gctttaagcc tgcagctgct ccgaaagtag
     8461 aagcaaaacc tgcagcacca aaagtaagtg cagaaaagaa agccgaaaaa tctgagccag
     8521 ctaaaccagc tgtagctaag gaagaggcaa aaccggctga gccagttgct ccgaaaacag
     8581 aaaaagtagc agtgaaaccg caaagtcgta atttcaaggc tgagcgtgaa gcccgtgcta
     8641 aagagcaggc agaacgacgc aagcaaaata agggcaataa ccgtgaccaa caacaaaacg
     8701 gaaaccgtca gaaaaacgac ggccgtaatg gtggaaaaca aggtcaaagc aaccgcgaca
     8761 atcgtcgctt taatgaccaa gctaagaagc agcaaggtca gcaaaaacgt agaaatgagc
     8821 gccgtcagca agaggataaa cgttcaaatc aagcggctcc acgtattgac tttaaagccc
     8881 gtgcagcagc cctaaaagca gagcaaaatg cagagtacgc tcgttcaagt gaggaacgct
     8941 tcaagcagta tcaggctgct aaagaagcct tggctcaagc taacaaacgc aaggaaccag
     9001 aggaaatctt tgaagaagcg gctaagttag ctgaacaagc acagcaagtt caagcagtgg
     9061 ttgaagtcgt ccctgagaaa aaagaacctg cagtggatac acgtcgtaaa aaacaagctc
     9121 gaccagacaa aaatcgtgac gattatgatc atgaagaaga tggtcctaga aaacaacaaa
     9181 agaatcgaag tagtcaaaat caagtgagaa atcaaaagaa tagtaactgg aataacaaca
     9241 aaaagaacaa aaaaggcaat aacaagaaca accgtaatca gactccaaaa cctgttacgg
     9301 agcgtaaatt ccatgaattg ccaacagaat ttgaatatac agatggtatg accgttgcgg
     9361 aaatcgcaaa acgtatcaaa cgtgaaccag ctgaaatcgt taagaaactt ttcatgatgg
     9421 gtgtcatggc cacacaaaac caatccttgg atggggaaac aattgaactc ctcatggtgg
     9481 attacggtat cgaagccaaa caaaaggttg aagtggataa tgctgacatc gaacgtttct
     9541 ttgtcgaaga tggttatctc aatgaagatg aattggttga gcgtccacca gttgttacta
     9601 tcatgggaca cgttgaccac ggtaaaacaa cccttttgga tactcttcgt aactcacgtg
     9661 ttgcgacagg tgaagcaggt ggtattactc agcatatcgg tgcctaccaa atcgtggaaa
     9721 atggtaagaa gattaccttc cttgatacac caggacacgc ggcctttaca tcaatgcgtg
     9781 cgcgtggtgc ttctgttacc gatattacga tcttggtcgt agcggcagat gacggggtta
     9841 tgcctcagac tattgaagcc atcaaccact caaaagcagc taacgttcca atcatcgtag
     9901 ccattaacaa gattgataaa ccaggtgcta acccagaacg cgttatcggt gaattggcag
     9961 agcatggtgt gatgtcaacc gcttggggtg gagattctga atttgttgaa atctcagcta
    10021 aattcaacca aaatatcgaa gaattgttgg aaacagtcct tcttgtagct gaaatccaag
    10081 aactcaaggc agacccaaca gtgcgtgcaa tcggtacggt tatcgaagcg cgcttggata
    10141 aaggaaaagg tgcggtcgca acccttcttg tacaacaagg taccttgaat gttcaagacc
    10201 caatcgttgt cggaaatacc ttcggtcgtg tccgtgctat gaccaacgac cttggtcgtc
    10261 gtgttaaagt tgctggacca tcaacaccag tctctatcac aggtttgaac gaagcaccga
    10321 tggcgggtga ccactttgcc gtttacgagg atgaaaaatc tgcgcgtgca gcaggtgaag
    10381 agcgtgccaa acgtgccctc atgaaacaac gtcaagctac ccaacgtgtt agccttgaaa
    10441 acctctttga tacccttaaa gctggggaac tcaaatctgt taatgttatc atcaaggctg
    10501 atgtacaagg ttctgttgaa gccctttctg cctcacttca aaagattgac gtggaaggtg
    10561 tcaaagtgac tatcgtccac tcagcggtcg gtgctatcaa cgaatcagac gtgacccttg
    10621 ccgaagcttc aaatgccttt atcgttggtt tcaacgtacg ccctacacca caagctcgtc
    10681 aacaagcaga agctgacgat gtggaaatcc gtcttcacag cattatctac aaggttatcg
    10741 aagagatgga agaagctatg aaagggatgc ttgatccaga atttgaagaa aaagttattg
    10801 gtgaagcggt tatccgtgaa accttcaagg tgtctaaagt gggaactatc ggtggattta
    10861 tggttatcaa cggtaaggtt gcccgtgact ctaaagtccg tgttatccgt gatggtgtcg
    10921 ttatctatga tggtgaactc gcaagcttga aacactataa agacgacgtt aaggaagtta
    10981 caaacggccg tgaaggtgga ttgatgatcg acggctacaa tgatattaag atggatgatg
    11041 tgattgaggc gtatgtcatg gaagaaatca agagataaga ttttttgctc ctttcttagg
    11101 tggtgaggga cgcaagcaaa ccgatggttt cattgcttat ttttgagcct agggtctcaa
    11161 aaatcccctg tgatgggact gataaatcag ttccatcact ttcaccacgg cgaaagaagc
    11221 agatgacttc aaattgaact tcgtttcaat ttaaactgaa aatcaagaag tttaaaatag
    11281 ctaggtctgc tggcctagct tttggttcaa agtagagaaa ggaatatcat ggcaaatcat
    11341 ttccgtacag atcgtgtggg catggaaatc aagcgtgaag tcaatgagat tttgcaaaag
    11401 aaagtccgtg atccacgtgt ccaaggtgtg accatcacag atgttcagat gctgggtgac
    11461 ttgtctgttg ccaaggttta ttacaccatt ttgagtaacc ttgcttcgga taaccaaaaa
    11521 gcccaaatcg ggcttgaaaa agcaactggt accatcaaac gtgaacttgg tcgcaatttg
    11581 aaattgtaca aaatcccaga tttgaccttc gtcaaagacg agtccatcga gtatggaaac
    11641 aagattgacg agatgctacg caatctggat aagaactaaa gaagaggggt tgcccctctt
    11701 tttcggctct ttgtcaactg tagtgggttg aagaaaagct aagctcgaga aaggacaaat
    11761 tt
//
LOCUS       DAVBEM010000059        11401 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVBEM010000059 DAVBEM010000000
VERSION     DAVBEM010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11401
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.059"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(<1..947)
                     /locus_tag="VQ548_001826"
     CDS             complement(<1..947)
                     /locus_tag="VQ548_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2654628.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQVIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFILVTFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTI"
     gene            complement(1027..1890)
                     /locus_tag="VQ548_001827"
     CDS             complement(1027..1890)
                     /locus_tag="VQ548_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET2654629.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(1893..3794)
                     /locus_tag="VQ548_001828"
     CDS             complement(1893..3794)
                     /locus_tag="VQ548_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2654630.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINCVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
     gene            complement(4222..4497)
                     /locus_tag="VQ548_001829"
     CDS             complement(4222..4497)
                     /locus_tag="VQ548_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HET2654631.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(4603..5442)
                     /locus_tag="VQ548_001830"
     CDS             complement(4603..5442)
                     /locus_tag="VQ548_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2654632.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVIVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            5584..6432
                     /locus_tag="VQ548_001831"
     CDS             5584..6432
                     /locus_tag="VQ548_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET2654633.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(6525..7442)
                     /locus_tag="VQ548_001832"
     CDS             complement(6525..7442)
                     /locus_tag="VQ548_001832"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HET2654634.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            7879..8084
                     /locus_tag="VQ548_001833"
                     /pseudo
     CDS             7879..8084
                     /locus_tag="VQ548_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(8395..8688)
                     /gene="rpmA"
                     /locus_tag="VQ548_001834"
     CDS             complement(8395..8688)
                     /gene="rpmA"
                     /locus_tag="VQ548_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HET2654635.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(8705..9049)
                     /locus_tag="VQ548_001835"
     CDS             complement(8705..9049)
                     /locus_tag="VQ548_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HET2654636.1"
                     /translation="MIQAVFERAEDGELRGAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(9065..9379)
                     /gene="rplU"
                     /locus_tag="VQ548_001836"
     CDS             complement(9065..9379)
                     /gene="rplU"
                     /locus_tag="VQ548_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HET2654637.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(9415..9502)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(9597..10196)
                     /locus_tag="VQ548_001837"
     CDS             complement(9597..10196)
                     /locus_tag="VQ548_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HET2654638.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDVR
                     DKLLTLITFIMGVFLLTIYKEKLRIVKKPILSLIPLAILSIIIGFVPQTVDNIYLVQP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLL
                     SSFVLGDVFSAYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            10666..10965
                     /locus_tag="VQ548_001838"
     CDS             10666..10965
                     /locus_tag="VQ548_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HET2654639.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            11184..>11401
                     /locus_tag="VQ548_001839"
     CDS             11184..>11401
                     /locus_tag="VQ548_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2654640.1"
                     /translation="MGQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGSQMKKYDFQKPSKIPYLETTGMPTR"
BASE COUNT         3615 a         2365 c         1895 g         3526 t
ORIGIN      
        1 aaaatcgtca taaacaattc acaaactaaa tttccagaaa aggaaagaaa agttggaagt
       61 ggtaatccca tcataaaaac tccgacacct gtcaaagcca gtaaaatcaa aagattataa
      121 atattagctt taattttact agctagaaga gccccaatga tggaaccaat agcccccata
      181 gttaaaatac ttgcataggc tccttctgac ccgtaaagct gattcgaaaa gggaagtaga
      241 aattcaaaag ctgcaaaaaa gaaattaacg ctggaagcta ccagcaaaag gaagaaaatt
      301 tcttgctgat gccagatata gtgtaaccca tccttgatat ctacaaaaat atctctccca
      361 gtaaaagcct ttttctcttg aacttttgct tcctcttttg gaaggaaagt cactagaata
      421 aaagcaatga aaaaagtcag cgagtctagc agtagcgtca tatggagact tgcaaactgt
      481 aaaacaagga aggaaagaac aggagagcta acacctacaa cctgcaaaac cagctctaag
      541 cgagaattat agatcacaat ctcatctttc tccaccactt cagttatgat agctttattg
      601 gctgtgcgag aaaaggcaaa agcaataacc tgcacaatgt tagcaacaat caaagcgcca
      661 atcatccagc tatcattcct tatgaaagaa atagccagac aaagaatccc acaaacaaga
      721 tctgccgtca ttaaaatctt acgacgagaa aaacggtctg aaataactcc gccaaaggga
      781 ttgacgagaa tagatgtgac gagctcagaa atctgataca ttcctaaaac tgtctgtcct
      841 atagtcccca tagaagccaa ccagacacta tttccataat catagagcat atttcccatt
      901 ttattgatag ccccacggct aatcaactgc actgcatagc gattcatatt aaagctcctc
      961 tcaaattttg aaactattgt atcaaaaccg aaaggagctt tttatttttt cccttatttg
     1021 ggaaaattaa cttttgacaa atttttcgta gtgttcctga taataggcta cttgctctgg
     1081 aagacctaac acatcaaaaa tatgcatggc ctcttgcatc tgcttacagc cttctttaca
     1141 ctgtcctttt tgatataagg caaaaccttt taaataatgg aaaacattac gctcataaag
     1201 cttaatacct ttgtcaataa tcttctctgt ataagcctca aaatagttgg cattataaaa
     1261 agaagaatgc tctaaacaat gctggtaaca attgagggcc aaaatcaaca ctaatctctt
     1321 atggcgacta atctcttggt aaaattcctc cctctccata acttctctac caatccgagt
     1381 gacatagtct acatcgtaga aactatagag gttaccgaaa agaatcaact catacatggt
     1441 ccattcttct gttttgaaga gataatctgc taccttatcc aaatcatcct gcttcatatc
     1501 ataactcgca tctctttgac aaatcagacc ttgtagcaaa atccagttca gctcaaaata
     1561 aagggaagtc gtcgaactct tagacttttc aagttgttct ctttgaagct tttgaaaacc
     1621 tgcaatatcg tttgaatagt aaagtgggat aatctgtgcc atcatagaca catgttcatg
     1681 attatgaaaa ttccttgcct tatccatgaa attttcgatt gttacatgaa tgttatccaa
     1741 aatctcaaag aaacgggaga ctgccaggtc agactcccca agctcaaagc gagataactg
     1801 agaggtagag caggattcgc ctgctgcttc ctttaaagaa taatttccac ttgttcgaaa
     1861 ttcacgaaat acttttccaa gatgttccat ctttacacct gatctgataa ttcttcccac
     1921 tcaagcatag cttcttcctg acgatggctg attttatcca gctcagcctg taattccatg
     1981 agtttgtcgg catcgtttgt ttccaacatt tgttcagaaa tggcttggct ttgactttct
     2041 agctcttcaa tttcagcttc tagactttcg atttgtcgca tgagtttgcg aacttctttt
     2101 tgactttctt tctgggcctg atagtcattg actggacttg cttcctttgc ttgattgcta
     2161 gttgaagctt cctcagtctg actcatttct gctgttgctt tcttctcaac atagtagtcg
     2221 taatctccaa ggtagagagt tgaaccattc tcagacaatt ccaaaacatg agttgccaca
     2281 caattgataa agtaacgatc atgactgaca aaaagcaagg taccatcaaa gtcaatcaag
     2341 gcattttcta gcacttcctt actatcaata tccaagtggt tggtcggctc atccagaatc
     2401 aaaaagttat tgttttccat agacaattta gctaaaagca aacgagcttt ttcgccacca
     2461 gatagcatgc cgactgattt tttaacatca tctcctgaga aaaggaaggc tccaagacgg
     2521 ttgcggattt caacttctgg tgtcaatttg aaatcattcc agagttcatc cagcaccgta
     2581 ttacttggtg tcagcttgct ttgggtttgg tcatagtaac caacctcaac attagcgcca
     2641 aagcgctttt ctcccttgat aaacggaatt tgatccacga ttgatttgat aaaggttgat
     2701 tttccgatac cattgggacc aacgatagca acagcattca tcttacgaag gtctaggtta
     2761 atcggttgtg acaggacttc cccatcatag ccaacagccg cattttcaac agtcaaaaca
     2821 acattgcccg acgttttttc agactggaag gtcatgttgg ctgctttctt gccagcttcc
     2881 ggcttgtcca aacgctccat tttttctagt tgtttacggc gagattgagc acgtttggtc
     2941 gttgaagcac gaactagatt gcgattgaca aagtcttcca gagcagcgat ttccttctgt
     3001 tgcttttcat agttttttgc ctcagtagct agcttttgct ccttcaactc gacaaaacga
     3061 gagtaattcc ccacatagcg atccaaggaa tgcttggtca aatctagcgt aattgtcgca
     3121 accttgtcca agaaataacg gtcgtggctg acgataatga gggcaccgct atagtttacc
     3181 aagtaattct ctagccagga gatggtttca atatccaagt ggttagttgg ctcgtccaag
     3241 accaagagat tgggcttttc aaggagcatt ttagctagag ccaaacgagt attttgacca
     3301 cctgaaagtt cagctatttt catctgccac atagactcgt caaacttgaa tccattcaaa
     3361 atcgctcgaa tatcagcttc ataggtaaag ccacctgctt ggcgaaaatt ctcagataag
     3421 cggtcataat ctgacatcag tttatccaaa tcctcaccag acttttcacc catctccagc
     3481 tccatctgac gcagttgtct ctccgtccga cgcaaatcat taaagacatg aagcatttca
     3541 tcgtagatgg tattttcaga ctcaaaacgg ctatcttggg ctaggtaaga cagagaaata
     3601 tcttttttct tattgatttc tccgctagtt ggctcctctt ctccaactaa aatcttcaaa
     3661 agagtagact tacctgcacc atttttccca acaagagcaa tccgatctcg ttcatcaacc
     3721 tgcaggttga tattatcgaa aagaacctct cctgcaaaag aacgttcaat tttattagct
     3781 tgtaaaataa tcataagagt agtatagcat gtttccctaa ggcattcaag ataatcgtaa
     3841 gtcttttagt acaactttta taacataaaa taaactaaat tatgtatatt ttatattaga
     3901 ttccttcact atcttgttgg attttctaac cagctaatct tgtttcaaat agttatcgca
     3961 caagcctatt atttaattct tttcattatt tacgtacgcg tatagcagat tgaaataaga
     4021 tgagaacaaa tcgattggga aagtaaaatt aatttctata aatgttttag caattgtttc
     4081 gtactatttt agattcagtc tactatgtac aatattttcg gaacattcaa ctttttaact
     4141 ctatttatta ctagatttca taattaaaaa gcctactgac caagctagaa agcttgatac
     4201 aataggcttt ttaaagactg attatttaac agcgtcttta agagctttac cagctttgaa
     4261 tgctggtact ttagaagctg caattgtcat ttctttacca gtttgtgggt tgcgaccttt
     4321 acgttctgca cgctcacgaa cttcaaagtt accaaaaccg atcaattgaa ctttttcacc
     4381 agctgcaaga tagtcagcta ctgctgcaaa tacagcttca actgctgctg ctgagtcttt
     4441 cttagtcaat tctgtagctt ctgctacttt agcgatcaaa tcttgtttgt ttgccatgtt
     4501 aatgattcct ccagataatt tctaattaac aaatataatc atatcctaaa atccctttta
     4561 ggtcaagtta aaaacgctat ttcttccaat tttatttatt ttttaggagt ggtaacgtat
     4621 caaaatagcc caagcgttct cacccgtgtg agtttgaata atggaacccg tttccaaaac
     4681 agaaattggc ttttcaacat aagcttgtaa gctttctttc atctcttttg cccaatcatc
     4741 actaccagaa tatgaaattc caatctctgc tacagcacgt tcagaaagcg atgttatcaa
     4801 ctcatctaac cattttttaa atgttttagt tccacgacct ttaaccattg gctgcaattc
     4861 atggtctttc atttgcatga caacacggat attgagaagg gagctcaaca agccagttac
     4921 acggccaatt cgtccacctt tgacaagatt ttccaaagtt gaaacaccaa tataaagctc
     4981 tgtatggttt ttaacctctt ctacatgaga taaaattgcc tccatatctt taccttcttg
     5041 agctaacttc gcagcctcaa caacttggaa tttcagggct tggtcagtga aggaactatc
     5101 aacaacaatc acatctgcag tagataggct agcaccttgg cgtgctgctt ctaccgtacc
     5161 cgaaagagca tgggacatat gaatagcaag aatctggcca ccatctttgc ataggtcttc
     5221 aaaaatctca gcaaagacac ctacaggtgg ctgacttgtt ttcggaagat tcttactttc
     5281 ttgcatcaac tgaagaaatt taccttcttc tttcaaatcc gcatcagaat aaacaacatt
     5341 atcaatcatt acagataatg gaacaattgt aatatctaat tgctttacta gttcaggttc
     5401 aatagtaaca gatgaatcgg ttacaatctt aatttttgtc atagtatcaa tctttctatt
     5461 ttaggattca gattggtttc cttacttcta attatatcaa aaaaaagatt aaaaatccta
     5521 atggagtcaa tcaaattttc cgtaaaattt gatataatca acttataaga aaagaggtgt
     5581 cctatgatta aaaaaattta ccccattttt accattttac taggtgctgc tatttatgct
     5641 tttggactga cttattttgt agttccccat catctctttg aaggaggggc gacaggtatt
     5701 accctcatca cattttatct ttttaaaatc cctgtttccc tcatgaacct gctgattaat
     5761 attccccttt tcatcctagc ttggaagatc tttggagcca aatccctcta ttctagttta
     5821 ctaggaacct tagctttgtc cggctggtta gctttttttg agcatattcc ccttcatatt
     5881 gatcttcaag gtgatttact aataacagcc cttatagcgg gaatcctatt gggaattggc
     5941 cttggaatta tttttaatgc tggaggtaca actggcggaa ctgatattct agctcgtatt
     6001 ctcaacaaat acactcatat atccatagga aaactgctct ttatcttaga tttttgtatt
     6061 ctcatgttga ttctcctaat cttcaaggat ttgagattgg tttcctacac gcttttgttt
     6121 gattttattg tttctcgtgt tattgatttg attggtgaag gaggatatgc cggcaaaggc
     6181 tttatgatta tcacaaaacg tcctgaccaa cttgctaagg cgattaatga tgacctcgga
     6241 agaggtgtta cttttatttc tggtcaaggc tactatagta aagaaaattt gaaaatcatc
     6301 tactgtattg tcggaagaaa tgaaattgtg aaaacgaagg aaatgattca tcgaatcgat
     6361 cctcaagcct ttataactat tacagaagcc catgaaatcc taggagaagg cttcaccttt
     6421 gaaaaagaat aaaaagaggt aatgtcgtga cctcaaaagt tagactaaat catctatctt
     6481 ttgggttaca gacaacctct tttttgtttt atttactcaa gctcttaaga ccaattccga
     6541 gttacttctt catcagcctt taactgatcc actaattggt caactgagtc aaatttggtc
     6601 atatcacgaa tgcgatcaag ccaataaacc atgacggttt ccccataaat atcttgatta
     6661 aaatcaaaaa tattgacttc aaaacgtgct tcttctccat caaaggtcac atttttcccg
     6721 acactagcca tagcacgata cttctgtctt tgaatctcaa catcaacgac ataaacgcca
     6781 tctgctggca tataagtacg gtctaaaagc actaaattcg ctgtcggata accaattgta
     6841 cgaccacgag cattaccatg aaccaccata cctcttgatg gaagcggtgc ccccaaaagt
     6901 tttcctgctt ctttcacatt tccatctaaa atagcttgac ggatacgagt tgaactaatc
     6961 tttcctttct catcttctac aggtggaaca atgataactt ctccatcaaa gtaatccttt
     7021 aaatcttctg ctgttttttt gtcagaacca aatgtataat caaaacctgc aacaataatt
     7081 ttggcattca tagccttgat ataagttgca aagaattctt gtgcagtgag actagcgaat
     7141 tgactactaa aatcaaggag atataattct tctacacctt cgcgctttaa ttttctttca
     7201 cgttcagcag ggttcaaaat atgcaaaaac aaatccggat gataaggctc taaagcgatc
     7261 tttggagatt cattaaaggt cataacgacg ataggtaata aatcctttct cgcagccttg
     7321 ttggcaacac gaaataattc ttgatgcccc ttatgtatgc catcaaaata gccgagaaca
     7381 acgactgaat cagatggtgt gccaatatct ttttggtttt ttataggaat agtaataatc
     7441 ataaaataat tatatcatag cgatagctat ttctggaaca gaaaatctga aatgttgttt
     7501 ttttcacatg aagtgtacct gttttcaaaa agcactttat tctatcgttg cttaactatg
     7561 aactttgcaa tattcttctc aaaaacttgt aggacatctt caaaattttg caaggagtga
     7621 ttagacttgt tcggtaacca taaagtgtca tactatgtta tgtatgaaaa agcaatgcaa
     7681 ctaactcctg agaactttaa attactaatt ggtgccgaaa aggtagaatt tagaatcgag
     7741 gtacacctat ggctgtaaaa tttacaaaat gagacaactt gggcaagatg tttgaagaat
     7801 ttcctaaact ccctgatttg aagcaagtca ctttccctga tgacaaagaa aaaagccaaa
     7861 acagcaaaga aaaactagat gactgctttc caacaactcc catctagtgt gcttcagact
     7921 gggctatttt tctctccatc tgttagcttg gattctcaga ccgtttcagc taaagaatat
     7981 cttttccctt atcagaagga acggctcaaa ccattcagac aagtgaaggg acgacaagcc
     8041 aatatttgaa accagatagc agttcttata gtcaattgaa ataaaatctg aagaaatcga
     8101 gtaggaaact catatcaatt tttaacagtg ttctattcca gattcatact caatgaaaat
     8161 taaagtgcaa actaggaagt tagccgcagg ctgtacttga gtacggcaag gtgaaactga
     8221 cgtggtttga atttgatttt cgaagagtat caatccacta tacatattaa aaagtatgga
     8281 tatcaaaaca aaaaaacagg ctctccgaaa actcggaaag ccttatttta agctgtttct
     8341 agcttcctca cctttacatt tcaaggttcg ggataaaagg ttcaatggac ctttttattt
     8401 agcgattggg taaacagaaa cttgtttttt atcgcgtcct ttacgttcaa agcgtactac
     8461 gccttcaact ttagcgaaca aagtatcgtc tccaccacga ccaacgttta cacctggata
     8521 gatgtgtgta ccacgttgac ggtaaaggat tgatccacct gttacagttt gtccgtcagc
     8581 tgctttagct ccaagacgtt ttgcttgtga atcacgtccg tttgatgtag aacctccacc
     8641 ttttttgtgg gcgaaaagtt gcaagttgtt aagagtcatt tttaacataa tgttttcctc
     8701 cgtgttagtt ttctgtgata actctggttt ggacgaactc agaatagttc tccgataagt
     8761 ttgccatacc taagaaaaat gattcaaaga ataactgggt catttctctc tggtgtgaag
     8821 gaagatcttt tggtatttca accatcagat agccaccttc atcttcgttt aattctagga
     8881 ttggttcata gcctgcaaat ttctcaatag aattgataaa gttaatggca agcgtagaaa
     8941 ccgatgcaca cacgacatct aagccgtatt cgccactctc ggcgtgtcca gtaatttccg
     9001 cacccctcag ctcgccatct tcggctctct caaagactgc ttgtatcatg tgttctcctt
     9061 aaaattaagc gttaattgcg ttgatgacaa cttttgtata tggttgacgg tgaccttgtt
     9121 tacggtggct acctttttta ggtttgtact tgtaagtaac aactttcttt tgttttcctt
     9181 gtttttcaac agttccaact acagtagctc cagcaacaag tggagttccg acaacagtgt
     9241 tttcaccacc aacaagaaca acttcgttaa aagtaacttc ttgaccagct tcaacgttca
     9301 atttttcaat gtaaactgct tgaccaactt caactttaac ttgttttccg ccagttttga
     9361 taattgcgta tgtgctcatt atgcacctcc tatgattttt atgggtttcc ccgatttttt
     9421 gtgaagactc gcctagcatc gtgggacaaa ccacttaaac ttgaataatc aagcaacgat
     9481 gttcgtgcgg ttgcacagga tcgtgcatag tcaactcttc aagtatagca tatctcctat
     9541 tttcttacaa gtaataacac ctaaaatcaa gctttttctt ttactttttt ctgccactag
     9601 gcaaaaagca tactgagata aaaaatgctc atcataatag gaacaccaag aatggtcttt
     9661 tcatgataga aaatcgtcaa ataggctgaa aagacatcgc caaggacaaa actactaagc
     9721 aggctaacaa atatgaaccc ttcacgcaaa aaaggagtgt gcttagttcg gaaataatct
     9781 ccaaaagcta gcattgttcg tttgatattc cctgtcataa aggcattatt gtaggcaata
     9841 cccgaaacct caccaaaagc agttgtcacc agtcccatac agaaggccaa gggctgcact
     9901 agatagatat tatctacagt ttgtggcaca aaaccaataa ttattgatag gattgctaaa
     9961 ggaatcaagg acagaatagg ttttttcaca attctcaatt tttccttata aatcgttaat
    10021 aaaaagactc ccattataaa cgttattaag gttaaaagct tatccctaac atccgaaaca
    10081 ttattttgta ttagctctac cgaaagaaag acaacatttc cagcttgtcc agctacaagg
    10141 gtattccctc gaacaataaa agtgtaagca tccacatatc cagcacaaaa tgtcaaaaaa
    10201 gtgctaacct tttagactga cgtgatattt ttcttatagg taataacctc attttccctc
    10261 ccattgtatt ttctcttaga aatattgtac catttctttc taaaaaatcg tagactacca
    10321 tttagatttt actattagca taaaaataat aatagacaac tatttatcca aaaatagata
    10381 gaggtaacat gtttgcaaac aaagcatacg aacctttagt aaaatcattt ccatgaaact
    10441 agaatagagc ccctcttagc aaaaatcatt attttaattt atttctaatc actccttgac
    10501 ataaataact ctcaccaata aaagactatg tcttaaaaaa atggtataat aaaatcaata
    10561 cctgggcttg atggctatgc tactaataac aattaggaga gaaaatcagg cacttgttaa
    10621 caacaaggat tatccccttg agatgaaagg aactttagaa atcttatgat gaacatgcaa
    10681 aacatgatgc gtcaagcaca aaaacttcaa aaacaaatgg aacaaagcca agctgaactt
    10741 gctgctatgc aatttgttgg caaatctgct caagatcttg tccaagcgac cttaactggc
    10801 gataagaaag ttgtcagcat tgatttcaat ccagctgtcg ttgacccaga ggaccttgag
    10861 actctttctg atatgaccgt tcaagccatc aactctgctc ttgaacaaat cgatgaaact
    10921 actaagaaaa aactgggtgc tttcgctggg aaattgccat tctaaaaaca aggagctaga
    10981 acaatacttg tcgataacaa aggctaagaa aggtgcaaaa attataaaaa acgcatagta
    11041 tcaagcaacc taaaactttg ggctctataa tatttgtagt gggtaaatcc actatagata
    11101 ttatggagcc tattttattg tagaaaaaaa tcccataaga tctataatga aaagcgacca
    11161 aacaactcat tagaaagatt catatgggac aattacattt tatcacaaaa ttactagaca
    11221 ttaaagaccc taatatccag attttagaca tcatcaataa ggatacacac aaggaaatca
    11281 tcgccaaact ggactacgac gccccatctt gccctgagtg cggaagtcaa atgaagaaat
    11341 atgactttca aaaaccgtct aagattcctt accttgagac aactggtatg cctactagaa
    11401 t
//
LOCUS       DAVBEM010000060        10989 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVBEM010000060 DAVBEM010000000
VERSION     DAVBEM010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10989
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.060"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            136..2316
                     /locus_tag="VQ548_001840"
     CDS             136..2316
                     /locus_tag="VQ548_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2654641.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDTSQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKNLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            2368..3183
                     /locus_tag="VQ548_001841"
     CDS             2368..3183
                     /locus_tag="VQ548_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET2654642.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETLVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            3323..4666
                     /locus_tag="VQ548_001842"
     CDS             3323..4666
                     /locus_tag="VQ548_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2654643.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLEIVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            5043..6233
                     /locus_tag="VQ548_001843"
     CDS             5043..6233
                     /locus_tag="VQ548_001843"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HET2654644.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            6786..7721
                     /locus_tag="VQ548_001844"
     CDS             6786..7721
                     /locus_tag="VQ548_001844"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HET2654645.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            7755..8792
                     /locus_tag="VQ548_001845"
     CDS             7755..8792
                     /locus_tag="VQ548_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET2654646.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNSSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            8965..9570
                     /locus_tag="VQ548_001846"
     CDS             8965..9570
                     /locus_tag="VQ548_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HET2654647.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            9726..10256
                     /locus_tag="VQ548_001847"
     CDS             9726..10256
                     /locus_tag="VQ548_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HET2654648.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            10277..>10989
                     /gene="rlmN"
                     /locus_tag="VQ548_001848"
     CDS             10277..>10989
                     /gene="rlmN"
                     /locus_tag="VQ548_001848"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HET2654649.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQGIVQESADGTVKYLFELPDGMLIETVLMCQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSISGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFP"
BASE COUNT         3341 a         2017 c         2395 g         3236 t
ORIGIN      
        1 tagaaatttt ttagaaaaaa gtgtaatttt tttataaaag cctttacaaa aaaaattaaa
       61 gtggtataat taaatcatag aaggtgcaaa cgttttcgta aaacgtttgc ctaaataaaa
      121 ataaaggaga tttgaatgat gaaagataca ttcaaaaatg tcttgtcttt cgaattttgg
      181 caaaaattcg gtaaggcttt gatggtagtt atcgcggtta tgccggctgc tggtttgatg
      241 atttcaatcg gtaagtctat cgtgatgatt aacccaacct ttacaccact tgtcatcaca
      301 ggtggaattc ttgagcaaat cggttggggg gttatcggta accttcacat tttgtttgcc
      361 ctagccattg gaggaagctg ggctaaagaa cgtgctggtg gtgctttcgc cgctggtctt
      421 gccttcatct tgattaaccg tatcactggt acaatttttg gtgtatcagg cgatatgttg
      481 aaaaatccag atgctatggt aactactttc tttggtggtt caatcaaagt tgctgattac
      541 tttatcagtg ttcttgaagc tccagccttg aacatggggg tattcgtagg gattatctca
      601 ggttttgtag gggcaactgc ttacaacaaa tactacaact tccgtaaact tcctgatgca
      661 ctttcattct tcaacgggaa acgtttcgta ccatttgtag ttattcttcg ttcagcaatc
      721 gctgcaattc tacttgctgc tttctggcca gtagttcaaa caggtatcaa taacttcggt
      781 atctggattg ccaactcaca agaaactgct ccaattcttg caccattctt gtatggtact
      841 ttggaacgtt tgctcttgcc atttggtctt caccacatgt tgactatccc aatgaactac
      901 acagctcttg gtggtactta tgacatttta actggtgcag ctaaaggtac tcaagtattc
      961 ggtcaagacc cactatggct tgcatgggta acagaccttg taaaccttaa aggtactgat
     1021 actagtcaat atcaacactt gttagataca gtacatccag ctcgtttcaa agttggacaa
     1081 atgatcggtt cattcggtat cttgatgggt gtgattgttg ctatctaccg taatgttgat
     1141 gctgacaaga aacataaata caaaggtatg atgattgcaa cagctcttgc aacattcttg
     1201 acaggggtta ctgaaccaat cgaatacatg ttcatgttca tcgcaacacc tatgtatctt
     1261 gtttactcac ttgttcaagg tgctgccttc gctatggctg acgtcgtaaa cctacgtatg
     1321 cactcattcg gttcaatcga gttcttgact cgtacaccta ttgcaatcag tgctggtatt
     1381 ggtatggata tcgttaactt cgtttgggta actgttctct ttgctgtaat catgtacttt
     1441 atcgcaaact tcatgattca aaaattcaac tacgcaactc cagggcgcaa cggaaactac
     1501 gaaactgctg aaggttcaga agaaaccagc agcgaagtga aagttgcagc aggctctcaa
     1561 gctgtaaaca ttatcaacct tcttggtgga cgtgtaaaca tcgttgatgt tgatgcatgt
     1621 atgactcgtc ttcgtgtaac tgttaaagat gcagataaag taggaaatgc agagcaatgg
     1681 aaagcagaag gagctatggg tcttgtgatg aaaggacaag gggttcaagc tatctacggt
     1741 ccaaaagctg acattttgaa atctgatatc caagatatcc ttgattcagg tgaaatcatt
     1801 cctgaaactc ttccaagcca aatgactgaa gcacaacaaa acactgttca cttcaaaaat
     1861 cttactgagg aagtttactc agtagcagac ggtcaagttg ttggtttgga acaagtaaag
     1921 gatccagtat ttgctcaaaa aatgatgggt gatggatttg cagtagaacc tgcaaatgga
     1981 aacattgtat ctccagtttc aggtactgtg tcaagcatct tcccaacaaa acatgctttt
     2041 ggtattgtga cggaagcagg tcttgaagta ttggttcaca ttggtttgga cacagtaagt
     2101 cttgaaggta aaccatttac agttcatgtt gctgaaggac aaaaagttgc agcaggagat
     2161 ctccttgtca cagctgactt ggatgctatc cgtgcagcag gacgtgaaac ttcaacagta
     2221 gttgtcttca caaatggtga tgcaattaaa tcagttaaat tagaaaaaac aggttctctt
     2281 gcagctaaaa cagcagttgc taaagtagaa ttgtaatata cttgaggttg gaagctgtat
     2341 tccaacctct tattttggga gaaaagaatg aaatttttaa cactcaatac tcacagttgg
     2401 atggagaaag aagcagagga aaaattccag attttgcttg aagatattct tgaaaaggac
     2461 tatgatttga tttgtttcca agaaatcaat caggagatga cctcgtcaga ggtggaggtt
     2521 aatgaccttt atcaagcttt gccagcagct gagcctattc accaagacca ttatgttaga
     2581 ctcttggttg aaaagttgtt agagcaaggg aaaaattact actggacctg ggcttataac
     2641 catatcggct atgaccgcta ccacgaaggt gtggctatct tgtctaaaac acctattgaa
     2701 gccagagaaa ttttggtttc agatgtggat gatccaacag actatcatac tcgccgtgtt
     2761 gccctagctg aaactttagt cgatggcaag gagctagcag ttgccagtgt tcatctctct
     2821 tggtgggata aaggtttcca agaagaatgg gcacgatttg aggctgtctt gaaaaaattg
     2881 aacaagccac ttttactagc tggagatttt aacaacccag caggtcagga aggttaccaa
     2941 gctattttag ctagtccatt aggcttacaa gacgcatttg aagttgctca agagaaaagt
     3001 ggtagctata ctgttccgcc tgaaattgat ggctggaaag ggaacactga accccttcga
     3061 atcgattatg tctttactac caaagagtta gcggtggaaa atttacatgt cgtatttgat
     3121 ggtaacaaga gtccacaagt gagtgatcac tatggcttga atgctatgtt aaactggaaa
     3181 taataactga aaagaggttg gaactataaa attccagcct tttcttacta gagaagctac
     3241 tggaaatagc ctaaataagt gagactactg taatggaata aaatatggta taattgataa
     3301 gatagataga atcgaggatg ttatgtcatt tacgaaattt caatttaaaa actatattag
     3361 agaagccttg aaggagttaa aatttacaac tccaacagag gtgcaagata agttgattcc
     3421 tattgttttg gcaggtcgtg acctagtagg agaatcaaaa acaggttcag gtaagactca
     3481 tactttcttg ttaccgattt tccagcaatt agatgaagct agcgatagtg tacaagcagt
     3541 gattactgca ccgagtcgtg agttggctac tcaaatttac caagtagcgc gtcagatttc
     3601 agctcactca gatgtcgaag ttcgtgtggt taattatgtg ggtggtacgg ataaggctcg
     3661 ccagattgag aaattggcaa gcaatcagcc tcatattgtt attggaacac caggccgtat
     3721 ctacgacttg gttaaatctg gtgatttagc tattcataaa gccaagacat ttgttgttga
     3781 tgaagcagat atgaccttgg atatgggatt cttggaaatt gttgataaga ttgctggcag
     3841 tcttccaaaa gacttgcaat tcatggtctt ctcagcgact atcccacaaa aactgcaacc
     3901 attcttgaaa aaatacttat caaatcctgt tatggagaaa attaagacta aaacggttat
     3961 ttctgacacc attgataatt ggttgatttc gaccaaggga catgataaga atgctcaaat
     4021 ttaccaattg actcagttga tgcagccgta tttggcaatg atttttgtta acactaaaac
     4081 gcgtgctgat gaattgcatt catatctgac tgctcaaggc ttgaaggttg caaaaatcca
     4141 tggagatatt gcccctcgtg aacgcaagcg aatcatgaat caggtgcaaa atctggattt
     4201 tgagtatatt gtcgcaacag atttagcagc gcgtgggatt gacattgaag gtgtcagcca
     4261 tgtcatcaat gatgccattc cgcaagactt atcttttttt gttcaccgtg ttggtcgtac
     4321 tggacgaaat ggcctaccag gtacagctat taccctttat cagccaagtg atgactcgga
     4381 tatccgtgag ttggagaaat tgggaatcaa gtttagtcct aagatggtca aagatgggga
     4441 atttcaagat acctatgacc gtgatcgtcg tgccaaccgt gagaaaaaac aagataaact
     4501 tgatatcgaa atgattggtt tggttaaaaa gaaaaagaaa aaagtcaaac cgggttataa
     4561 gaagaaaatt caatgggcgg ttgatgaaaa gcgccgtaaa actaagcgtg ctgaaaatcg
     4621 cgctcgcggt cgtgcagagc gtaaagctaa acgccaaaca ttttaataga aattgttgga
     4681 gtactgagct ccaacttttt tatttatgag aacgaactat ctaaaccgaa acactacatt
     4741 aaagactgca aattgcgatt aaaaatggta taatgataaa gttatatagt cccgataaga
     4801 tggtaggtat ttattacgaa gagttttcct atcagtagtt tgcaattcgc aaagaatgac
     4861 ggcttcgagg tcgctcgtct ttctacggtt gccgccatac tgcggtcacc ctatgcgcct
     4921 tactagcttc agaaataaaa aagtatcgtt tttatttctg aagctagtaa ctcttagata
     4981 atggaaattc ctatcagtac tttgtaactc tataacaata ttttttaagg ggggacattt
     5041 ttatgtcaga acgtaaatta ttcacgtctg aatctgtatc tgaggggcat ccggataaga
     5101 ttgcagacca aatttcagat gcgattttgg atgctatttt agcaaaggat ccagaggcgc
     5161 acgttgctgc tgaaacagct gtatatactg gttctgtcca cgtttttggt gaaatttcta
     5221 caaatgccta tgtggatatt aaccgtgtgg ttcgtgatac cattgcagag attggttata
     5281 ccaatacaga atatggattt tctgctgaga cggtgggagt acacccatct ttggtggaac
     5341 aatctcctga catcgctcaa ggtgttaacg aagccttgga ggttcgtgga aatgctgatc
     5401 aagatccact ggacttgatt ggagcaggtg accaagggct catgtttgga tttgcagtag
     5461 atgaaacaga agagctcatg ccattgccaa ttgcactcag tcataaattg gttcgtcgtc
     5521 tggcagaact tcgtaagtct ggagaaatta gctatctccg tccagatgca aaatcacaag
     5581 ttacagttga gtacgatgaa aatgaccgtc cggtacgtgt agatacagtc gttatttcta
     5641 ctcagcatga tccagaggcc actaatgaac aaatccatca agatgtgatt gacaaggtca
     5701 tcaaagaagt tattccatct tcttatcttg atgataagac aaaattcttt atcaatccga
     5761 caggtcgttt tgtaatcggt ggtcctcaag gggactcagg tttgactggt cgtaagatta
     5821 ttgtagatac ttatggtggc tactctcgtc atggtggtgg tgccttctct ggtaaagatg
     5881 cgactaaggt ggatcgttca gcctcttatg cggctcgcta tattgccaag aatatcgttg
     5941 cagcaggcct tgctaagaag gcagaagtgc agttggccta tgctatcggt gttgcgcaac
     6001 ctgtttctgt tcgtatcgat actttcggta caggaacagt agctgaaagt caacttgaaa
     6061 aagcggctcg tcaaatcttt gaccttcgcc ctgcagggat tatccaaatg ctggacctca
     6121 agcgtccaat ttaccgtcaa acatcggctt acggtcacat gggacgtaca gatattgatc
     6181 ttccatggga acgtttggat aaggtagatg ctttgaaaga agcagtaaaa taagatttta
     6241 agaggggaac gtcctctctt ttttatagtt tttaactata ctgggatact gttctgaaaa
     6301 tccattttgc gaaagtagag atttacatgt ataatggatt gaaactagaa tagtacacct
     6361 caacttctaa aacattgtta gaaatcgatt tgactgtcct gatcgatttc tcctgttctt
     6421 gtttcatttt actatatttc tttaaaaatg ataaaggttg agatttctcc tcgtaataga
     6481 taatcatggg gatatttcaa tccaaagttt tattcgttat cacttgacta ttgcaaggtt
     6541 ttctagagca acagagtcat ggaatggact catggttgag atttctcctt gttgcttgga
     6601 cttcattcaa aagtctgtta cccaagcctt gttcaaactt ccaatacact agctgtttcc
     6661 atagcatgac ttctgtacta gactttcttt tccgaataaa tagatagaac cacagaatct
     6721 agtaaaccta gaattaaaat tatggtataa tattagcaat aaaagaaatc tggaggatta
     6781 gaatcatggt atcaacgaaa acacaaattg ctggttttga gtttgacaat tgcttgatga
     6841 atgcagcagg tgtggcttgt atgacgatag aggagttaga agaggtcaaa aactcagcgg
     6901 caggaacctt tgttactaag acagcgacct tggacttccg tcaggggaat cctgagccac
     6961 gctaccaaga tgttccactt ggttccatca actctatggg cttgccaaat aatggcttag
     7021 actattattt ggattatctt ttagatttgc aggaaaaaga gtcgaaccga actttcttct
     7081 tatctctggt cggcatgtct ccagaggaaa cccatactat tttgaaaaaa gtccaagaga
     7141 gtgattttcg tggtctgact gagctaaatc tttcctgtcc aaatgttcca ggtaaacctc
     7201 agattgccta tgattttgag acaacagacc ggattttggc agaagtgttt gcttacttca
     7261 ccaaacctct tggaattaaa ttgccacctt attttgatat tgttcacttt gaccaagcgg
     7321 cagctatttt caacaaatat ccgctcaagt ttgtcaactg tgttaactct atcggaaacg
     7381 gcctctatat agaagacgaa tctgtcgtta ttcggcctaa gaatggtttt ggtggaattg
     7441 gtggagaata catcaaaccg actgctctag ccaatgttca cgccttttat caacgtttaa
     7501 atcctcaaat ccaaattatc ggaacaggtg gcgttctgac tggtcgagat gcctttgaac
     7561 acatcctctg tggagcaagt atggtgcagg tgggaacgac ccttcacaaa gaaggcgtca
     7621 gtgcttttga ccgcattacc aatgaactga aagcaatcat ggtggaaaaa ggctacgaga
     7681 gcttagaaga tttccgtggg aaattgcgct atattgacta aattaaatcg aaaaatctga
     7741 agaaaggaga gacgatgcta gccattgaag aaagtcagaa gttgacttta tcaaatttac
     7801 cgagcctgag cctatttaca gggacagatc agggtcagtt tgaagtgatg aagagtcaag
     7861 tgttgaaaca gattgggtat gattctgctg acctcaactt tgcctacttt gatatgaaag
     7921 aagtagttta caaggatgtg gaactggagt tggtcagcct tcctttcttt gcggatgaga
     7981 aaatcgtgat attagattat tttatggata tcacgactgc taagaaacgc tttttgacag
     8041 atgatgagct taagtcattt gaggaatacc ttgacaattc ttctccaaca accaagttga
     8101 taatctttgc agaaggaaag ctggatagca aaagacggtt agtcaaatta cttaagcgtg
     8161 atgccaaggt cttcgatgca gtagaagtaa aagaacaaga attgcgccag tatttccaaa
     8221 agtggagtca gaaacaaggt ctgcagttta ccaatcattc ttttgaaaat ctcctcatca
     8281 agtcggggtt tcaatttagc gaaatccaga aaaatcttct ctttttacag tcctataagg
     8341 cgaattctgt tattgaggaa gaggatattg ttaacgcaat tcccaagacc ttgcaggaca
     8401 atatttttga tttaactcag tttattctga ctaaaaagat ggatcaggcg cgcgatttgg
     8461 tgagagactt gaccttgcaa ggggaagatg aaatcaaact gattgcagtc atgctgggac
     8521 aatttcggac ttttactcag gtgaagattt tggcggagtc tggccaaaca gaatcgcaga
     8581 ttgcaagtag tttaggtagt tatctgggac gtaacccaaa tccttatcaa atcaagtttg
     8641 cattaagaga ttcgagagga ctttctttga gctttctgaa gcaagctatt tcctatttga
     8701 ttgagacaga ctatcagatt aagacaggtc tttatgaaaa aggtttcctt tttgaaaagg
     8761 cactcttaca gattgctagt caggtcaatt gacatttgtt gaaactacaa cccgcgtcag
     8821 gattatcttg tcgtgggttt cttgctgatt tgcttatttt attagaaagt atgtcagtga
     8881 tttccttatc tataagcaaa aaacttgaaa aaagtgaatg tttgcgttat cattttcata
     8941 tagaaagaaa aagaggtatt acagatggct attatcttac cagaacttcc atatgcatac
     9001 gacgctttgg aaccatacat cgatgcggaa acaatgcatt tgcaccatga caaacaccat
     9061 caaacttatg tcaacaatgc caatgcagct ttagaaaaac accctgaaat cggtgaagac
     9121 cttgaagcct tgcttgctga tgtagaatct atcccagctg atatccgtca agcacttatc
     9181 aacaatggtg gcggacactt gaaccacgct cttttctggg aattgatgac tcccgagaaa
     9241 acagctcctt cagcagaact ggcagcagca atcgatgcaa catttggttc atttgaagaa
     9301 ttccaagcag ccttcactgc agcagcaaca actcgttttg gttcaggttg ggcatggttg
     9361 gttgtcaaca aagaagggaa acttgaagtg acttcaacag caaaccaaga cacaccaatc
     9421 tcagaaggta aaaaaccaat cttgggcttg gacgtttggg aacatgctta ctacgtgaaa
     9481 taccgcaacg tgcgtcctga ctacatcaaa gctttctttt cagtaatcaa ctggaataaa
     9541 gtagatgaat tgtacgcagc tgctaaataa tgatagttgg agggaagaat tgttcttctc
     9601 tttttaggtt ataagattct ggtctgacaa aatcgtcaga cttttttcat ttttatgaga
     9661 aacgtgctaa ctgctagaaa ttatggtaga ataaagtatt aagtaatcgt ggaaaaagga
     9721 tatctatgcg aaaagaaatt gcacctgaat tatacaacta taacaagttt cctggtccgg
     9781 agttccattt acacggggat aaggtcgaaa cggaagggat agctttttcc ttggttgaaa
     9841 atatcaagga tgcctttgat gtgacgactt ttaatcagcg tttttcagaa gtcttaacca
     9901 agtttgatta tatcgtgggg gactggagca acgaacagct tcgcctacga ggtttttaca
     9961 aggatgaccg aacagaagaa aaacttgaaa aaatcagtcg tttacaagac taccttttag
    10021 agtattgtag ttatggttgt gcctattttg tcttagaaaa tgaagcccct aagcgagcat
    10081 catttgacaa gaaaatgcgt aagacggaag aagaaacacc ttctagaaaa ggaaagaaac
    10141 cgactcaaac taaacgaaag tcgaatgcag ataagaaaaa tagacgtcgt cagaaagacc
    10201 agcattctca gaaagaggac aaggaacaac gtcattttgt cattcgtcag aagtgagtag
    10261 agaataagga gaagaaatga aaccctcaat tcatagtttg gcacatcaaa ccatgcagga
    10321 atgggtattg gagcagggag aaaagaaatt ccgtgcagat caaatctggg aatggctcta
    10381 ccgtaaacgt gtgcagtcat ttgaagaaat gaccaacctt tccaaggatt tgattgctaa
    10441 gctcaatgac cagtttgtgg tcaatccctt gaaacaaggt attgtgcaag agtctgctga
    10501 tggtacagtc aaatatctct ttgaattgcc tgacggtatg ttaattgaga ctgtactcat
    10561 gtgtcaacac tatggtttat ctgtctgtgt gaccactcag gtcggctgta atatcggttg
    10621 taccttctgt gcctctggtt tgattaagaa gcagcgtgac ctcaataacg gtgaaatcgt
    10681 agcgcaaatc atgctggttc agaaatactt tgatgagcgt ggtcaggatg aacgcatcag
    10741 ccatatcgtt gtcatgggaa tcggtgagcc ctttgataat tacaacaatg tcttgaattt
    10801 ctttcgtact atcaatgatg ataaaggaat ggctatcggt gctcgtcaca tcacggtttc
    10861 aatctcaggt ttggctcata aaattcgtga ctttgctgat gaaggggttc aggtcaatct
    10921 tgccgtgtct cttcacgcac ccaacaatga acttcgttca agtatcatga agattaaccg
    10981 tgcctttcc
//
LOCUS       DAVBEM010000061        10791 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVBEM010000061 DAVBEM010000000
VERSION     DAVBEM010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10791
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.061"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            135..425
                     /locus_tag="VQ548_001849"
     CDS             135..425
                     /locus_tag="VQ548_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654650.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKNAKNCVRLSQLSLNKR"
     gene            449..1165
                     /locus_tag="VQ548_001850"
     CDS             449..1165
                     /locus_tag="VQ548_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2654651.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSIGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(1294..2109)
                     /locus_tag="VQ548_001851"
     CDS             complement(1294..2109)
                     /locus_tag="VQ548_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HET2654652.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(2106..3011)
                     /locus_tag="VQ548_001852"
     CDS             complement(2106..3011)
                     /locus_tag="VQ548_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HET2654653.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMLFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
     gene            3409..5538
                     /locus_tag="VQ548_001853"
     CDS             3409..5538
                     /locus_tag="VQ548_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HET2654654.1"
                     /translation="MDKKYEKISQDLGVMLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            5525..5974
                     /locus_tag="VQ548_001854"
     CDS             5525..5974
                     /locus_tag="VQ548_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HET2654655.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            6033..6305
                     /locus_tag="VQ548_001855"
     CDS             6033..6305
                     /locus_tag="VQ548_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET2654656.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(6659..6850)
                     /locus_tag="VQ548_001856"
     CDS             complement(6659..6850)
                     /locus_tag="VQ548_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654657.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            7278..8036
                     /locus_tag="VQ548_001857"
     CDS             7278..8036
                     /locus_tag="VQ548_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2654658.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            8038..10026
                     /locus_tag="VQ548_001858"
     CDS             8038..10026
                     /locus_tag="VQ548_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2654659.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYSVKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKALTLNDHQFSVKEEFTKDFIVNHVPNQF
                     NILTADYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVNASEAEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(10068..10712)
                     /locus_tag="VQ548_001859"
     CDS             complement(10068..10712)
                     /locus_tag="VQ548_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HET2654660.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNEEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLEQLFSI"
BASE COUNT         3339 a         2019 c         2255 g         3178 t
ORIGIN      
        1 tataccatat tttgtttcgc aggaagtcta atgctaaaat cttatcagtg agaagatttc
       61 ttaaagttta ttctttgtag tttcatctgt attagtacat aatttaactt agagaaaata
      121 ggaggactaa tcgaatggaa ttaaaagatt ttacagaaaa agaacaggaa atgattaaga
      181 aaaggcttac aatgtctaat attagtgaca aagaaactac tgagaagatt ctggcgctag
      241 tcccacaaga cttgattaag cgaatcccgt tttttgtcag aaaacatgct acaacacgta
      301 cgattaaacg tatttcaatt gaataccctg aactctacgc tgtagctcaa acaagtggtg
      361 agattccaga aaaaaacgcg aagaattgcg tcagattatc acaactatct ttgaacaaaa
      421 gatgaataag catagtatta agtagagaat gaaaaaatat tttattggcg gtttgggaag
      481 caatgcctat catagcaagg attttcttca agaactagat tcgcaggtct attttctaaa
      541 tccatatgaa aagcatcttc gagatgaaac agaattgaaa tcatggttta aaaatgagat
      601 tgtagaggaa gaatctatct gtctgatagg tcattctatt ggaggcgatt tagctcgtta
      661 tttcgcatcg gaatttgaag aagtaaagaa actgattctt ttggatggtg gctatctaga
      721 tttagataag attttacctt tggatacaga gttagaggaa actaaaaatt atatcaaatc
      781 tcaaattatt tcggacttag atgttcttac ttctaaagaa aaatctgaag caaagcattg
      841 gtcagaaaat atggagaaag ctgtaagaca gtcctatcac tggaatgttg agtataatag
      901 atatgagttg gctataaatt atgaaaatat agaagcgata ctccgcctac ggagaaaaat
      961 acaagctttt aagagagaag tgggagatac cttgtttatt agtcctcgct atcctaatga
     1021 agctacatgg agagaggaag ccctaaaaga attgccagac tattttgata ctattttttt
     1081 agaaaacttt ggccatgagc tttatactca agcacctaaa gaaatcgcta gtctaatgaa
     1141 tgagtggctc gcttattttc tatgagctac ttgtattgct ggaaatggta taagatgaaa
     1201 atctacaagt cactaatttt catataacaa aaaacgaaca ggctcttttt ctgttattca
     1261 gaagagaact tgttcgtttt tatcttgatt ttcttaaaaa gctctatata catagggatt
     1321 ttctggttta tcgactttgg taaagctgtc gatttccaag gttggaaggt tttgtttgag
     1381 ttctttatgg tagtgattga ccagttttcc tttggctgtt atccaagtgt tgttttcata
     1441 ctgccgggta ttgcccttgg tcagcaatcc atagacacca gaatctgcga tacagtggat
     1501 aatgccgaat cggaacagaa attgactatt ggcatgactg gggtcgttat agacaaagcc
     1561 tgtaaactgg attgtcttgc cctcaaactc atctggatag tcgtagatag cctccatgac
     1621 ttccatatag ttttcattag tgatctgaat actatcttgg gataagtatt tatccgccgc
     1681 cgttcgcatt tccttttcat aggctgattt tgaaaaataa gaactggtat ctggtttcaa
     1741 atattggctt gtcgtccctt cgcttgtctg aatggctaga tctgttcctt ccgatagggg
     1801 gaaatgataa cctttagcag aaacggtctg agaatccaag ctaacagttg ggaaagttaa
     1861 gccgatgaca agtggaatag ccagaagaga aatactcgtc atcttggcca atcggctgtt
     1921 cagatgactg tgggttttga cttgcttcat ccagatatac aattgaacaa ttgccaagat
     1981 aaaggaaagc accatggaga tataggccag ataggaatag tgcatgttga tgtactggtt
     2041 tagtttgccc gacagatgga ggtaaatagt cagttcaaaa tagccagcta aaactaaaaa
     2101 tcgaatcata ggatgactcc aatcaagaga gaatagacta agacgacaag agttacaatc
     2161 gttatgaagt gactgataaa tcgtgctttc aagtaatttt tcatcatgag aatatttttg
     2221 atatccagca ttggaccaat gacgagaaag gccagaactg gtgccaaacc gaaactcgag
     2281 agaagagaag cacctataaa ggcatccgcc tcactacaga gcgaaagaag aaaggccaaa
     2341 atcatcaaga gcaggatggc aaaaagagga gtcgcactga tagaggtcag aatccgagtc
     2401 ggaacgtaga cctgtattat agaagcaaag aggcagccaa ataccaaata acgccccgta
     2461 tcaaaaaatt catcaatggc ctgcacaaag acttgaaaaa ctttttttgc agaactcaag
     2521 taagaaaaat catgctcatg acaagccaga cgattttctt tctgaatcgg ttcttgccag
     2581 aaaaatccta gaaaaattcc tagtattaca gccacaagaa tggaacccag agctcgtaat
     2641 agggcgacat ggaaggagtt gccaaaggca gaataggtcg caaaaagaac aatgggattg
     2701 ataacaggtg ctgtcacaag aaaaggaacg gctgtgtaac tgggaacctt tttttccaga
     2761 aaacgattga tgatggggac gattccacat tcacaagaag ggaaaagcat accgacaaag
     2821 gtcccaaaaa agattctccc ccaacgattt cgagggagaa aatgataaac cttgtcaggt
     2881 gtgatataaa cttcaatcag ccctgagaca atgcttccta ttagaacgaa gggaagggct
     2941 tcaatgataa tggagagaaa aatggctcca gtttgaagta cactagatgg gagttgttga
     3001 aaagcagtca tctagttttt cttttctgct ttggcttttt tctctttgtc atcagggaaa
     3061 gtaacttgtt tcaaatcagg gagtttagca aactcttcaa acatcttgtc caagtcgtct
     3121 cgttttgtaa attttacagc cataggtgta cctcgattct aaagtctacc tctattatac
     3181 tattattttg cggaaaaggg agttttttaa tttgttttcg atagttgata cacttcgaaa
     3241 atctcttcaa accacgtcag cttcgcctta ccgtatatat gtgacttatc cacaacctca
     3301 aaacagtatt ttgagcagcc tgcggctagc ttcctagttt gctttttgat tttcattgag
     3361 tatgaaaagg attggagaaa gccttccagc ttgtggtata atagatttat ggataaaaaa
     3421 tatgaaaaaa tctctcagga tttgggagtg atgttaaagc aaattgatac cgttctaagt
     3481 ttgacagctg aaggggcgac tattcccttt atcgcgcgtt atcgcaagga catgactggt
     3541 agtctggatg aggtggcgat taaggctatt attgatttgg ataaaagtct gacaaatctc
     3601 aatgaccgta aggaagctgt cttagctaag attcaagaac aaggtaagtt gaccaaggaa
     3661 ttggaagaag ctatcttagt tgccgaaaaa ttagcagacg ttgaagaact ctatcttcct
     3721 tataaggaaa agcgtcgtac caaggcaacc attgcccgtg aagctggact ctttcctctt
     3781 gctcgtttga ttttgcagaa tatagttgac ttagagaaag aagctgaaaa gttcgtctgt
     3841 gaaggatttg cgactggcaa ggaagccttg accggtgcag ttgatatttt ggtcgaagcc
     3901 ttatcggaag atgtgacctt gcgttctatg acttatcagg aagtgctgag acactctaaa
     3961 cttacttctc aagccaagga tgaaagtctt gatgaaaagc aggtttttca gatttattat
     4021 gatttttcag agacagttgg aactatgcaa ggctatcgta ccttggctct caatcgtggg
     4081 gagaaacttg gtgtcttgaa gatcggtttt gaacatgcga cggaccgtat tcttgccttc
     4141 tttgctactc gtttcaaggt gaaaaatgct tatattgatg aagttgttca gcaatccgtt
     4201 aagaaaaagg tcttgcctgc tatcgagcgt cgtattcgga cagaattaac tgagaaagct
     4261 gaagaaggag ctatccaact tttttctgac aatctgcgca atctcctctt ggttgctcca
     4321 ctgaaagggc gcgtggttct tggatttgac ccagcctttc gtacaggtgc caagttagct
     4381 gtcgtggatg caacaggaaa aatgctgaca actcaggtta tttatcctgt taaaccagca
     4441 tcagctcgtc aaatcgaaga agccaagaaa gatttagcag atttaattgg tcaatacggt
     4501 gtagagatta ttgccattgg aaatggaacg gccagtcgtg aaagtgaagc ttttgtagcg
     4561 gaagttctga aagatttccc tgaagtcagc tatgttatcg ttaatgaaag tggtgcttct
     4621 gtctattctg ccagcgaact tgctcgtcag gagtttccag acttgaccgt tgaaaaacgc
     4681 tctgccattt ctatcgcccg tcgtttgcaa gatcctcttg cggaattggt caaaatcgat
     4741 cctaagtcaa ttggtgtcgg tcaataccaa cacgatgtca gtcagaagaa actatctgag
     4801 agtctggact ttgttgtcga tacagtggtt aaccaagttg gtgtcaatgt caatacagct
     4861 agcccagctc ttctttcaca cgtagctgga ctcaacaaaa ctatctctga aaatattgtc
     4921 aaataccgcg aggaagaagg aaaaatcact tcacgcgccc aaatcaagaa agttcctcgt
     4981 ctgggagcca aggcctttga gcaggctgct ggtttccttc gtatccctga aagtagcaat
     5041 atccttgata atacaggagt tcacccagag aattacactg cagttaagga actcttcaaa
     5101 cgtttagata ttaaagacct aaacgaagaa gcccaaagca aactcaagtc cctttcagtc
     5161 aaggaaatgg ctcaagagct agacctcggt ccagaaaccc ttaaagatat cattgcagat
     5221 cttctcaaac caggtcgaga tttccgtgat tcctttgacg cacctgtgct tcgccaagat
     5281 gtcctagata tcaaagacct agtggtaggt cagaagctag aaggtgttgt gcgtaacgtt
     5341 gttgacttcg gtgccttcgt tgatatcggg attcacgagg acggcttgat tcatatttct
     5401 catatgagtc gcaagtttat caaacaccct agtcaagtgg tgtcagttgg agatttggtg
     5461 accgtttggg tcaagaaaat tgatactgaa cgtgaaaaag ttaatctgtc gctcctcgct
     5521 ccaaatgaaa ctgactgatt atgtcaagca ggtttcacta gaagacttcg ggagagcttt
     5581 tatccatcat gtccagtgga ataggcgtct acgttcgaca ggtgggcgat ttttccccaa
     5641 agatgggcat ctggatttta atcccaaggt ttatcagaaa ctgggtatgg aggtttttag
     5701 gaaaattgtc cgacatgaac tctgtcatta tcacctttat ttccaaggga agggctatca
     5761 acacaaggat cgggatttta aggaactgtt gaaagcagtg gatggattaa ggtttgtacc
     5821 atccttgccc aatagtaact ctaaaccact caagctttat cgttgtcaat cctgccagca
     5881 aaggtatcag cgcaagcgta ggattgatac caaacgctat cgctgtggac tttgtcgagg
     5941 taaattgctt ctgataaatc agcctgagga ctgatgaaag ccgagcctcc ccgtgatata
     6001 ctatgtctaa cctagcagaa agaggaaata tcatgaacag taaattttat aaaatgagac
     6061 gcaatcgcat gatttcagga gttctggcag gtctgtcaga caagtggaat tttgatgtta
     6121 ccctagttcg tttcttgttt gccattttta cagttgcaaa ctttggactt ggcgtgatta
     6181 tctatatcat cctagcttct atcatgccta ccaaggaaga aatcgaagca gaaatgtacg
     6241 gaacaggccc acgtaaacgc aaagaagccc aagccattga cgacaatgaa ggctggtttt
     6301 ggtgaggttc tacagaagat ttggaataag caaaaagctt taaatcaata gtctaaactg
     6361 cttgatttaa agctttttta cttttatact caataaaaat caaagtgcaa actaggaagc
     6421 cagccacagg ctgtaattta gtcggcaatg tgaagttgac atagtttgca ctttgatttt
     6481 tgaatagtat taataatatt tcgccagctt catccacaaa ctatagtgga ttggaactag
     6541 aatagtacac ctctacttct aaaacattgt tagaaatcga tttgactatc ctgatcgatt
     6601 tgtcctgttc ttatttcatt ttattataaa agcagtaatt taaactcagt tttttaatct
     6661 atttttgctg ctgagacaat acatttttgg aaaaatggtg gatgctgata acaactgata
     6721 accagcaaat aacataagca gtgccggtaa attctgtacc gataaagtgt gtgtgttcaa
     6781 ctaagagctg accgatgaat ggagagagca gatagagaag tccgatgagt atatgttctt
     6841 tgtgtttcat taaagcgcac cttctttcct tataggttga acgacttgca agtgttaaat
     6901 tgaatggtat gttatctagg taagcttact caaatgatag ttcccgcttc ctcctttcca
     6961 aagtaagcct tttcatactt atattttaca actttaaaaa taggaaatca aatcattttc
     7021 taagtaattt tgcttatatt tcacccaatc ttacaaaaat gtaagattaa agtctctttt
     7081 gtaaggttag gttatggcaa gcggtctttt tttgatgtaa actagactca taaagaacaa
     7141 aggagtaaca tcatgaaaca aatcttacat aagaaaacta gaaaaccaag tcacaaagaa
     7201 attgagcgcg ttcagctggg atgcactatg atgcaagcta catttcattt gatgggatat
     7261 taagaaagga gattctcatg acacttttag atgtaaaaca cgttcaaaaa atttataaaa
     7321 cacgttttca gggcaaccaa gtagaagccc tcaaggatat tcactttacc gtcgaaaagg
     7381 gtgactacgt tgccatcatg ggtgagtctg gttctggtaa atcaactctt ctcaatattc
     7441 tagctatgct ggataaacca agtcgtggtc aggtttactt gaatggaact gacaccgcaa
     7501 ccattaaaaa ttcacaggcc tctagcttcc gtcgtgaaaa gttgggcttt gtcttccaag
     7561 actttaactt gctagatact ctatctgtaa aggacaatat cttgcttccg cttgtcttgt
     7621 caagaagacc tattacagag atgatgaaga aattggtggt gacagctgag aatctgggaa
     7681 taaaccaatt acaagagaag tacccttacg agatttctgg tggccagaaa cagcgtgtag
     7741 cagtagcacg cgccatcatc actgaacctg aaattctcct tgcggacgaa ccgacaggag
     7801 ctcttgactc caagtcatct gcagccttac ttgatgtctt tgatgaaatc aatgagcgcg
     7861 gccaaaccat tctcatggta acccactcaa cagcagcagc tagcagagct aaacgtgtac
     7921 tctttatcaa agacggcatt ctttacaatc aaatctaccg tggagagaag acagaacgtc
     7981 agatgttcca agaaatctct gataccttga ctgtcatggc aagcgaggtg aattagtatg
     8041 tttcgattaa ccaataagtt agcggtatcg aacttgatta aaaaccgcaa actctactat
     8101 ccttttgcgc tggctgttct cttggcagtc actgtcacct atctctttta ctctctaacc
     8161 ttcaatccca agattgctga aattcgtgga ggaacaacca ttcaggctac acttggattt
     8221 ggtatgtttg tcgtcaccct tgcgtcagcc attatcgttc tctatgccaa tagttttgtc
     8281 atgaagaacc gttccaagga actaggaatt tatggcatgt tgggcttgga gaagcgtcat
     8341 cttatcagta tgacctttaa ggagttagtg gtatttggga ttctaactgt tggagcgggt
     8401 atcggtattg gagccttgtt tgacaagtta attttcgctt tcctgctcaa actaatgaaa
     8461 ttgaaggttg agctggttgc taccttccag acgaaagttg tcattacagt gcttgttgtc
     8521 ttcggtttga ttttcctagg cctcatgttc ctgaatgccc ttcgaatcgc ccgtatgaat
     8581 gccctccagc tctctcgtga gaaagctagt ggagagaaaa aaggtcgctt ccttcctctc
     8641 caaaccattc ttggttccat aagtttagga attggctatt atcttgccct tacggtaaaa
     8701 gatcctctta cagccttaac aaccttcttc atagctgttt tactggttat ctttgggact
     8761 tatctcttgt ttaatgcagg gattaccgtt ttcctccaaa tcttaaagaa aaataagaaa
     8821 tactattacc aaccaaataa tctcatatct gtttctaact tgattttccg tatgaagaaa
     8881 aatgcagttg gactagccac catcgctatc ttgtcaacaa tggttttggt aaccatgtca
     8941 gcagcgacaa gcattttcaa ttcctcagaa agctttaaaa aagttctaaa tcctcatgat
     9001 tttggggttt cagggcaaaa tgttgaaaaa gaagacttgg acaaactctt gagccagttt
     9061 gcaagtgaca aaggttatag tgtcaaagag aaagaagtac ttcgttacag taactttggt
     9121 attgcaaatc aagaaggaac taagttaact atttttgaaa aaggacaaaa ccgtgtccaa
     9181 ccaaaaacag ttttcatggt atttgaccaa aaagattatg aaaatatgac tggtcaaaaa
     9241 ctgtctctat caggaaatga ggtcggactc tttgcaaaga atgagggagt taaagaacag
     9301 aaagctctaa ctctaaatga tcatcaattt tctgtaaaag aagaatttac taaagatttt
     9361 attgtcaacc atgttccaaa tcagtttaat attttgactg ctgattacaa ttaccttgtt
     9421 gtacctgatt tacaagcctt tttggatcaa ttcccagatt cggctatcta taatcagttt
     9481 tacggtggta tgaatgtaaa tgccagtgaa gcagaacaac tcaaggtcgc tgaggagtat
     9541 gaaaaatact tacaaaagtt taatgctcaa ttaaacactg aaggtaacta tgtgtatggt
     9601 agcactctag cagatgctag tgctcagatg agtgccctct ttggtggtgt cttctttatc
     9661 ggtattttct tatccattat ctttatggtc ggaaccgttc tggtcatcta ctacaaacaa
     9721 atttctgaag gatatgaaga ccgtgagcgc tttattatct tgcagaaagt cggtttagat
     9781 caaaagcaaa tcaagcaaac catcaacaaa caggttttaa ctgtattctt ccttcctttg
     9841 ctctttgcct tcctacatct agcctttgcc taccatatgc ttagtctgat tttaaaagtg
     9901 attggtgtac tggatacgac tatgatgttg attgtgacct tgtctatctg cgctatcttc
     9961 ctcatcgcct atgtgctgat tttcatgatt acttcaagaa gttatcgcaa gattgtgcaa
    10021 atgtaaaaaa gatacctcga cttcaaaatc gaggtatttc ttgtattcta aatgctgaaa
    10081 agttgttcga gcaggaaggt aactcccatg gtcaagagac caatagcaag gttccgaatc
    10141 atagctgttt tggttggggc ttttccaagt ctagcacttg tgtaaccagt gagaagaagg
    10201 gccacaccga caataaggac ggtagcaggg atgcggtaat cacttggaaa aatggtcact
    10261 gacagcattg gaggcaaact tctaaggaaa aaggcaacga agctagaaat ggcagcgtgc
    10321 caaggattgg taaattcttc atactcaatc ccatattttt cctctaccag agccttgagt
    10381 ggatttttaa gaaagatctt attagtcaag agttgggcag aagttttgaa ttcttcattt
    10441 tggatataag cagcatagag ggattttttg gctagttccc tatcttggtc tagcaagagt
    10501 ttttctcgcg aaacggcagc ttcctcggta tcttttggag ttgaaacgga tacatattct
    10561 ccaccagcca ttgaaaaggc accagctaag atagccgcaa atcctgataa aaagataatc
    10621 cagatattgg tcgtggcact ggcaaccccg ataaccacac cagcaatgga aataattcca
    10681 tcgttagcat caagaacacc cgcacgcagg atatttaaac gacctgcaaa atttgaatca
    10741 atttcgtgat ttgtttctga cgctaaattt caagttcaag ttagccatcc a
//
LOCUS       DAVBEM010000062        10604 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVBEM010000062 DAVBEM010000000
VERSION     DAVBEM010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10604
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.062"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(7..1221)
                     /locus_tag="VQ548_001860"
     CDS             complement(7..1221)
                     /locus_tag="VQ548_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2654661.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(1377..1670)
                     /locus_tag="VQ548_001861"
     CDS             complement(1377..1670)
                     /locus_tag="VQ548_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654662.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVKVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            1832..2284
                     /locus_tag="VQ548_001862"
     CDS             1832..2284
                     /locus_tag="VQ548_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HET2654663.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(2319..3707)
                     /locus_tag="VQ548_001863"
     CDS             complement(2319..3707)
                     /locus_tag="VQ548_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2654664.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            3773..4735
                     /locus_tag="VQ548_001864"
     CDS             3773..4735
                     /locus_tag="VQ548_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HET2654665.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(4732..4923)
                     /locus_tag="VQ548_001865"
     CDS             complement(4732..4923)
                     /locus_tag="VQ548_001865"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654666.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDETDEVSSKHVFEVVDRTDEVS
                     NHTYGRATLTWFAEIFEEY"
     gene            complement(4987..5997)
                     /gene="ccpA"
                     /locus_tag="VQ548_001866"
     CDS             complement(4987..5997)
                     /gene="ccpA"
                     /locus_tag="VQ548_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HET2654667.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKVGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(6422..7021)
                     /locus_tag="VQ548_001867"
     CDS             complement(6422..7021)
                     /locus_tag="VQ548_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2654668.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(7022..8119)
                     /locus_tag="VQ548_001868"
     CDS             complement(7022..8119)
                     /locus_tag="VQ548_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2654669.1"
                     /translation="MLERLKSIHYMFWASLIFMIFPILPVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLFWGIMLIYVAGNTAFVAVNYIWFFFFLSNLLSYHFSVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYLLGILTFVDLMTLGSVRIRLVEDLKEAQ
                     TKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQIQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVEIANQLDTASLTQEL
                     ESTASMILLELVTNIIKHAKASKAYLKLERTDQELLLMVRDDGKGFETVTENELHTVR
                     ERVLPFSGEVSVISQKHPTEVQVRLPYKERK"
     gene            complement(8119..8856)
                     /locus_tag="VQ548_001869"
     CDS             complement(8119..8856)
                     /locus_tag="VQ548_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2654670.1"
                     /translation="MKRWIALNKIEFLLTKRQSVYYLLSVGMPTAFYLFFSGMYQDTP
                     GGPANFMRDYLISMTAFSMMSTAIFSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMMVDYLVSILVVFSVGHLVRGVDMSLGSWIGAAFLLIVGSIAFVALGLTLTLLPSS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAIGKCLPTYQLMELLKTFLNEGSINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(8858..9742)
                     /locus_tag="VQ548_001870"
     CDS             complement(8858..9742)
                     /locus_tag="VQ548_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2654671.1"
                     /translation="MNMIKVQGLHKNIKSKAILKDISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVYIQDLPVTSSKLDYTRSYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLNNQEIDQLLQFDQQQKEQFAEKLSGGQKRLLSFILTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVRDLKAQGVTILYSSHYIEEVEHTADRILVLNKGELIRDTTPLAMRSE
                     EIEKHFILPLAYKEVVEKSVLVENWVQKQDALQVVTCEADAFWELLVQAGCRIQEIEV
                     NNRSLLDTIFEETQKGDD"
     gene            complement(9729..9923)
                     /locus_tag="VQ548_001871"
     CDS             complement(9729..9923)
                     /locus_tag="VQ548_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654672.1"
                     /translation="MKKAILFLFIGLSLVVWLVEMFTGWFDQSFLHQVIRGAWGLGFM
                     ISVVFPMGMEWLKGEYYEHD"
     gene            complement(9920..10126)
                     /locus_tag="VQ548_001872"
     CDS             complement(9920..10126)
                     /locus_tag="VQ548_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654673.1"
                     /translation="MEEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEGFYHFPWELFAS
                     FGIMSWLIREGLKLVRDVKKELEK"
BASE COUNT         3213 a         2412 c         1931 g         3048 t
ORIGIN      
        1 caagccctat ctacgatact gtttcaagaa acgagtcatc ttttcttgga tttgggctaa
       61 ctcatcaaca cgaggaaggt aaacgatacg gaagtggtct ggttcctgcc agttaaagcc
      121 tcgaccatga accaagagaa ccttttcctg cttcaagaaa tcaaggacaa actgctcatc
      181 atcatcgata cggtacatat tgcggtcgat ttttgggaag atatagagcc ccgccttggg
      241 tttaacggca gacaaacctg gaatatcttg aatggcatta tagatgaaat ttctttgctc
      301 gtagattcgt ccaccaggaa gaagcaattc atcgactgat tggtgacccc ccaaggaagt
      361 ttgtacgact tgttgggcca aaacgttaga gcaaaggcgc atattggaca gcatattgag
      421 cccttcgata tagcccttaa catgagtctt agggccagac aagaccatcc aacccacacg
      481 gaaacctgct atgcggtggg attttgacag accattcatg ctgacacaga agacatctgg
      541 tgccaagctc gccacaggcg tatgcacatg tccgtccatt accatgcggt catagatttc
      601 atccgcaaag ataatcaaat cgttttgacg ggcaatctca ataatctcca gcaagagttc
      661 cttaggataa agggctccag ttgggttatt tggattgata aggacaattg ccttggtatt
      721 ggaagtgatt tttgacttga tatcgtcaat atctgggtac cattccacag cttcatcaca
      781 gatatagtga acggcatttc ctccagctag gctgacagcc gccgtccata gaggatagtc
      841 tggcattggc actaagacct catccccatt gtccaaaagc ccctgcatgg acatgacaat
      901 caactcactg acaccatttc caaggtaaat atcatcaata tctacgtttg ggaatttctt
      961 cagctggcaa tactgcatga tggccttacg ggctgagaaa atccctttgg agtcagaata
     1021 gccttcacta tcacgcgcat tcataatcaa gtcatgaatg acctcgtctg gcgctgtaaa
     1081 gccaaattct gctggatttc ctgtattcag acgtaaaatc ttttctccat tcgctcgcat
     1141 ccgcatggct tcttccaata caggaccacg gatatcataa gcaacatgct ctaacttact
     1201 agacttgtta tattctttca tcttgtttcc tcaattcatc aggatagtaa cattatacca
     1261 ctagaaagag aatgcgacaa gtttactgaa atgtgttact agtttcgtat agaagaaaaa
     1321 ccttgctaaa ggcgaggtta agaacgtaga gatagcaggc attttgcaaa gacacatcac
     1381 ataccaaaag ataaacctag aaaaagcaag cctagaaagg agtcataaag aagattaaac
     1441 atgaggaaaa gcccccatat catcaagtaa tcccaacgcc cacttcgttt tgcaactaga
     1501 aataagatta gatggtagag tacatgaaag actaaaaatc caataaaact tggataaaga
     1561 agcggtacca gactctctaa ttgacagatc atgatcactt ttaccaagac tgaaactagg
     1621 ataattccat aatacaggaa atttgatttt tgaaaagagt ttttcatcat tctcccttcc
     1681 ttcacttctt tccttctatc ctttctttta ttttatcata tatttatata gattttaagc
     1741 cctaatattc ttttgaaaaa tacttttttt gctttacttc tatagtgaaa aggtttacaa
     1801 ttatagtaag aaaatttcag gaggtttcat tatggcacaa cgttaccaaa atatcatggt
     1861 cgcaatcgat ggttctaagg aagcggactt ggcttttgtc aagggagttc attctgctct
     1921 acgaaacgac gctaaactca ccatcgcaca tgtcattgac acacgcgctc tccaaagcgt
     1981 atccaccttt gatgctgaag tttacgaaga actccaagtc gacgctgaaa gtctgatgaa
     2041 agagtacgaa aaacgtgcta aagatgctgg ggtagcagat gttcatatcg tcattgaaat
     2101 gggaaatcca aagaccctgc tagcacgtac tattccagat gccgaggaag tggacctcat
     2161 cctcgttggc gcaactggtc tcaacgcctt tgaacgcctc ttggtcggct cttcatctga
     2221 atacatactc cgccatgcta aggtcgattt gctggttgtg agagaacaag aaaaaacctt
     2281 ataatcacaa agaaaaggag cccctagctc ctttttgttt acgatttatt tctctcttta
     2341 tggcgttcgt aagccttgag ctggcgctgc agttcctttt taatagcagg ttctggagca
     2401 tatttttctt cccaattatc tggttttaag attttatggg tcactggatc aaaatgagcc
     2461 ttgccatctg gaaaaatttt ccccatattg gcctgatgga caatatcaaa aatacgttct
     2521 gggtccaccc ccatcaagac aaaactgccg taggtgaagt aaagcgtgtc aatcaaggca
     2581 tccacttgcc ctatcaaatc ttgctgagca ggtgtcttct tggctacttt acctgctgcc
     2641 ttatcaaggg cctgatgaag ttgcgataca gcttgaccaa aatcttcttc agaaggactg
     2701 gctgctcgaa caaactccac caattcttct attttaaaac cagccctatg ggttgcaccc
     2761 tctaaatccc aagctcgagg ttcttcttgg gttcgttcat ccatcatgtg gtggaaggtc
     2821 ttgaccttat tgaaatgata gtcacggctg acaaagactt tttctgaaga caaaacacca
     2881 aaatgttcca aggccttgtg gatcccatct tgttgattgc tagtggtaat gtgcttggca
     2941 gcttccttga cactgctact accatttccc atagcgaccg acataccgac gccagccagc
     3001 atttcaaggt cattatctga gtcaccaaaa gccatgactt ggttgaggtc aaagccatat
     3061 tctttcccaa ctcggcgaat gccttctaat ttagaatttc cctgattgat gacatccgat
     3121 gcaaaaggat tgctacgtgt caatttcaag tcttcaaaat cagctgccgc cttctcagat
     3181 tcttctggtg tcatcagcat caaaacttgg tagataggct gattcatcag gtgaagcagg
     3241 tcctcttcct tttggggaac aaccttgctg accatgcgat taaaagactg actcaccgtc
     3301 cgagttaaaa cagagggaac gaagcgacta attcgttggg aaaaagaacc cagaccaaag
     3361 gacatgattt tagaacccaa catggcatcc ttggtcccta gggcaatctc cgtgccctct
     3421 tttttagcat agctaattag atggcgcaaa tgtaacttgg aaatagggct cgtgaacaag
     3481 actctgtctt tactaaagat atactggcca ttataggtta ccgcaaaatc cagatccaaa
     3541 tcgtccatca attccttaac aaaaaaaggt cctcgccctg tcgctacgcc aactagtacc
     3601 ccttgttctt tgacaatctt aatcgcgtcc ttagtggatt tcaaaacact cttgcgattg
     3661 ttgaccaagg ttccatcgat atcaaaaaaa acagctttga cttccatcct attccaatct
     3721 ccccttttgt gatacaatga ttataccaca tttcagaaag agtgagtaaa tcatgcctaa
     3781 gaaaatcctt gttttacata cgggtggaac tatttccatg caggccgatg cttctggcgc
     3841 tgttgtgacg agttcagata atcccatgaa ccatgtgtcc aacccacttg aaggaatcca
     3901 agtccacgcc ttggactttt ttaaccttcc aagtccccat atcaaaccca aacatatgct
     3961 ggtcctctac cagaaaatta aagaggaagc agataactac gatggagtgg taatcacaca
     4021 cggaaccgat actttagagg aaacagccta tttccttgat accatggaag ttccccatat
     4081 gcctatcgtt ctaacaggag ccatgcgtag ctccaatgag ctcggtagtg atggtgttta
     4141 taattaccta agtgctttac gagtggccag cgatgacagg gctgctgaca aaggagtttt
     4201 ggtcgttatg aacgatgaaa tccacgctgc caagtatgtc accaaaacac atacgactaa
     4261 tgtcagcacc ttccagactc caacacatgg ccccctcggt ctcatcatga aacaggaaat
     4321 cctctacttc aaaacagctg aacctcgtgt tcgctttgac cttgatcaca tacaaggttt
     4381 agtccctatc atctcggctt atgctggtat gacagatgag ctgattgata tgctggattt
     4441 agaacacttg gacggtttga ttatccaagc cttcggagct ggtaatattc ccaaagaaac
     4501 ggctcaaaaa ttagaaagcc ttctgcaaaa aggaatccca gtcgctctgg tatcacgatg
     4561 ctttaacggt attgccgagc ctgtttatgc ctaccagggt gggggcgtac agttgcaaaa
     4621 agcaggcgtt ttctttgtta aagaactcaa cgcccaaaaa gctcgcttga aactcctcat
     4681 cgccctcaat gccggactaa caggacaggc tttgaaagac tatatggaag gctaatactc
     4741 ttcgaaaatc tctgcaaacc acgtcagagt cgccctaccg tatgtatggt tactgacttc
     4801 gtcagttcta tctacaacct caaaaacatg ttttgagctg acttcgtcag tttcatctac
     4861 aacctcaaaa cagtgtgttg cgcagccttt aaccagccgc ctagtccgct ctatggtatt
     4921 cattaagtca acatctcttg tttaagagca caaaatcagg aaatcttctc gattccctga
     4981 ttttttctat ttacgttttc gtgttgagct acgttctgtc aaaccatgag gtaagagaac
     5041 ttcacgttct tccaactctt ccttatgcat aatcttggtc aacatacgca tactaatggc
     5101 accaaggtca taaagaggtt gggcaatcgt tgtcaagttt ggacgggtaa agcgtgagat
     5161 ttgtgaatca tcactagtaa taatttcaaa atcttctggc acagaaacac ccttatcagc
     5221 caaaccgttc aagactcctg ctgccaactc atcacctgtc acaactgctg cagttgcatt
     5281 tgatgaaatc aaacgctctg ctaaggcgta accatcatca tagctatatt tagattcaaa
     5341 taccaaaccc tcactataag tgattcctac ttttttcaag gtttccttgt agccaactaa
     5401 acgaacctta ccattgatgt catccactag cggaccgcta acgaaagcaa tacgctcatt
     5461 ttctttagca aggtagctca ctgcatcaat tgttgcttgc ttatagtcaa tattgacact
     5521 tggcaactgg tgctcaacat cgacagttcc tgcgagaaca atcggagtac gtgaacgcga
     5581 aaattctgag cgaattttat ctgtcaagtg ataacccata tagataatgc catctacctg
     5641 ctttgaaaag agggtattga caacagaaac ttctttctcg ttatcttcat cgctattagc
     5701 taggacaata ttgtacttgt acatttctgc aatatcatca atccccttag ccaaactcga
     5761 aaaataacca ttggtaatat ttggaatcac gacaccgaca gtggttgtct ttttacttgc
     5821 aagaccacgc gcaactgcat ttggacgata atccaaacga tcaattacct ctagcacttt
     5881 tttacgggta ttctctttta catttttatt gccattgacc acacggctga ccgtcgccat
     5941 ggaaacacct gcttcacgag cgacatcata aatggttact gtatcatctg cattcattcc
     6001 ttttcctgtc ctttctatct cacacattct tttacaagta gaggtactga ttgaagctct
     6061 atatctactt acaaaagtga agatgtgaaa atttcgtttt catatttcta cttattccat
     6121 tctatcacta attgtaaaca ctttcaagtg ttttttgaag attgattgaa aaaatttcat
     6181 agaaaaccta ggtttagctc cttgctacca ccttagacta aataaaaagg aggaaactaa
     6241 gcccttctaa agttatagta aaatgaaata agaacaggat aaatcgatca ggacagtcaa
     6301 atcgatttct aacaatgttt tagaagtaga ggtgtactat tctagtttca atctactata
     6361 ggtattgttc cattcactac cgtcaatttt agcacatagt cttcatgaaa atattatatc
     6421 atcataacca accagattct tttgcgatat tagctgcctc tgttcgatta ccagcatcca
     6481 gttttgaaag aatattggtg acatagtttc gaatagttcc gtttgagagg taaagctgat
     6541 ctgcgatttc ttggttggat aagccccggg cgattccctt taagacagca atctcttgtt
     6601 ctgtcaacgg attgggacgg gtcatcacca cttccatcaa ttcaggcgaa tactccttgc
     6661 gtccttcgag gacggtgtgc aaggtttgca tgaggtctgc aatgcttcgt tcctttaata
     6721 cataagcatc cactccagcc ttgaccgcac gttcaaaata cccagcacgc ttgaaggtcg
     6781 tcaccacaac cacctttgtt tcaagccttt ctgatcgtat ccactccaag acttcaagac
     6841 ctgtcttaac aggcatttct acgtcaagga tggcgatatc tacagactcc ttttctaata
     6901 gttggattgc ttcttgccca ttcttggctt gaaggacaga ctccacatct ggttgaagcg
     6961 tgagcaattg acacatagca tctcgcaaca tactttgatc ttctgcgact aatactttca
     7021 tctactttct ctccttataa ggtagtcgaa cttgcacttc cgttggatgt ttctgactga
     7081 ttacacttac ttctcctgaa aatggaagga cacgttctcg aactgtatgg agctcatttt
     7141 ctgttacagt ttcaaaacct ttcccgtcat ctctgaccat caggagcaat tcctgatctg
     7201 tgcgttctaa ttttaagtag gctttagacg ctttagcatg tttgatgatg ttggtcacta
     7261 attcaagcaa aatcatggaa gccgttgact ctaattcctg agttaagcta gctgtatcta
     7321 gttgattagc tatttccacc tcaattccag caatttctaa catctttttc acagtctcta
     7381 gttcggatgt caaagttcta gacttaagat tttccacaat ggttcgcact tcacgcattg
     7441 attctttgct aatctgctgt atttctctta attccttttc cacttgtgga taagcctgta
     7501 tttgaaataa ctgcaaggct agatcagttt taacactaag catagcaaag gtatgcccca
     7561 gactatcatg caaatcttga ccgatacgat tgcgctcatt ttctgctagc aatagattta
     7621 tctgggtatt ttgcttagtc tgagcttctt tcaaatcctc gacaaggcga attcgaaccg
     7681 agcccaaagt catcaaatca acaaaagtaa gaattccaag cagatagact agaaactcaa
     7741 cttcgattct ctgaaaaatc aaaagtcgcc ccacaacaag gacttgagca agaagaaaag
     7801 tccagacatg taaagacttt aaactacgta cgctgaaatg ataacttaag agattggaaa
     7861 ggaaaaagaa aaaccagata taattcacag caacaaaggc ggtattccca gctacataga
     7921 tcagcatgat cccccagaaa agccaagata ggcgctggct cttagttgtt aaaacaccca
     7981 aatatgccac tacaaataga atatcaatca ataaatgcca ggcagaaagc cacccagtca
     8041 ctacaggtag gatggggaaa atcataaaaa ttaaactggc ccaaaacata tagtgtatgc
     8101 ttttcagtct ttcaagcatt aagcattctc cttatgacct tgaaggtaaa tggtcaaacc
     8161 aaacaaaact gctgaaaaaa caagtagata aactgtggct gatagattga tgctaccctc
     8221 gtttaagaag gtcttgagca actccatcaa ctgataagtt ggtaggcact tcccgattgc
     8281 ttgcatccag tctggaaata aagagatggg catccagagt ccacctaaaa cagccaagcc
     8341 tagatagaga agattgccca cgacagacat cagctgacta gaaggcaaga gtgtcaaggt
     8401 caagccaagc gctacaaaag ctatacttcc tactatcagc aagaacgcag ccccaatcca
     8461 gcttcctaaa gacatatcca cacctctgac caagtgccca actgagaaaa caaccaggat
     8521 tgagaccaaa taatcaacca tcatacttgt tatctttgat agataatatt ctaccatatt
     8581 tacagggcta tgacgcaatg ttttctgcca gttgttcatc ttatcggtat gtaagacagc
     8641 tgggaatgaa aagatagcgg tcgacatcat ggaaaaggca gtcatggaga tgaggtagtc
     8701 gcgcataaaa ttagccggtc cacctggtgt gtcctggtac atgcctgaaa agaatagata
     8761 gaaggctgtc ggcatcccta cagataataa ataatagact gattgccgtt tggtcaatag
     8821 aaattctatc ttgtttagtg caatccatcg tttcatctta gtcatctccc ttctgtgttt
     8881 cttcaaagat tgtatccaac aaactacgat tattgacttc gatttcttgt atcctacatc
     8941 ctgcttgaac taacagttcc cagaaagcat ccgcttcgca tgtgactact tgtaaggcat
     9001 cttgtttttg tacccagttt tcaaccaaga ctgacttctc aacgacttcc ttgtaagcta
     9061 gcggaaggat aaaatgcttt tcaatctcct cactacgcat agctagaggc gtcgtgtcac
     9121 gaatcaactc tcccttattt aaaaccaaaa tccggtcagc tgtatgctct acctcttcaa
     9181 tataatgaga cgaatagaga atggtgactc cttgcgcttt taggtcccga acaatttccc
     9241 aaaaacgttg acgagttgaa gtatccatgg cagcagttgg ctcatctaaa aagacaagct
     9301 ttggtcgccc aattaaggtc aagataaaag ataaaagacg cttttgccca cctgacaatt
     9361 tttctgcgaa ttgctctttc tgttgctggt caaactgtaa tagttgatcg atttcctggt
     9421 tgttcaaggg atttggatag atacgttgaa agaaagcaat caactcttta acctttagtt
     9481 tttgaacaat tacattttct tgagggagat aggatctcgt atagtctaac ttagagctcg
     9541 ttaccggcaa atcttggata tatacttgcc cactggtgac caatttatct ccaagcaaac
     9601 agtccaagag tgtcgtctta ccagctccat ttggcccaat caaggcgacg cattcacctt
     9661 cagctacctc aaaggaaata tccttcaaaa tagccttact tttgatgttt ttatgtaagc
     9721 cttgtacctt aatcatgttc ataatattct cctttcaacc actccattcc catagggaaa
     9781 acgacggaaa tcataaatcc taatccccag gcgccgcgaa taacttggtg aagaaaggat
     9841 tgatcaaacc aacctgtaaa catttctacc aaccatacca ctagtgatag tccaataaaa
     9901 agaaagagaa tcgctttttt catttttcaa gctccttttt cacatctctt actaatttca
     9961 agccttctcg tatcaaccaa gacatgattc caaagcttgc aaacaactcc caaggaaaat
    10021 gatagaatcc ttcgtccaat cctgagaaca tgagataagt catgactcct gctactacta
    10081 aactcactgc gataatcatt ttatttctca tctcttcttc ctccatttca tactacaatt
    10141 atagtctttt gaaatcagag gagatagaag cttctgtcac taaaaaatat gacaaatgtc
    10201 ataaaaaatt ctgttcaaaa caagcaagat acactataca ataaaacaca attagataaa
    10261 tctaaggcaa cttcctcaaa agagatatca aaccccattc acactataat gtaaactaat
    10321 acttatttaa agtcaaaaga gcggaaattt ttatcgtaca aacatatata ttataggtaa
    10381 gacaaaaaac tcttcaatta ctttcttaaa aatttatagg agttataaaa tctattaaat
    10441 ttcaatgtgg atacctaaac tacagtattt attgaaaaga ctggagacaa aaagtatacg
    10501 ctgccaaaat gaattgctga aaatcaaaaa agagagaagc aaactgattc tctcttaatg
    10561 tatataatat ctagttataa aaatacacac tcacatatct ctgt
//
LOCUS       DAVBEM010000063        10045 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVBEM010000063 DAVBEM010000000
VERSION     DAVBEM010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10045
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.063"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(103..1806)
                     /gene="ilvD"
                     /locus_tag="VQ548_001873"
     CDS             complement(103..1806)
                     /gene="ilvD"
                     /locus_tag="VQ548_001873"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HET2654674.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(2039..2971)
                     /locus_tag="VQ548_001874"
     CDS             complement(2039..2971)
                     /locus_tag="VQ548_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HET2654675.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATNNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(2968..3825)
                     /locus_tag="VQ548_001875"
     CDS             complement(2968..3825)
                     /locus_tag="VQ548_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET2654676.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(3829..5175)
                     /locus_tag="VQ548_001876"
     CDS             complement(3829..5175)
                     /locus_tag="VQ548_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2654677.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMVIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSATEE"
     gene            complement(5188..5472)
                     /locus_tag="VQ548_001877"
     CDS             complement(5188..5472)
                     /locus_tag="VQ548_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2654678.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(5476..7506)
                     /locus_tag="VQ548_001878"
     CDS             complement(5476..7506)
                     /locus_tag="VQ548_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET2654679.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NSHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            7698..8705
                     /locus_tag="VQ548_001879"
     CDS             7698..8705
                     /locus_tag="VQ548_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET2654680.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            8708..8908
                     /locus_tag="VQ548_001880"
     CDS             8708..8908
                     /locus_tag="VQ548_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2654681.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            9060..9242
                     /gene="rpmF"
                     /locus_tag="VQ548_001881"
     CDS             9060..9242
                     /gene="rpmF"
                     /locus_tag="VQ548_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HET2654682.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKITKAASAE"
     gene            9258..9407
                     /gene="rpmG"
                     /locus_tag="VQ548_001882"
     CDS             9258..9407
                     /gene="rpmG"
                     /locus_tag="VQ548_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2654683.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(9899..>10045)
                     /locus_tag="VQ548_001883"
     CDS             complement(9899..>10045)
                     /locus_tag="VQ548_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2654684.1"
                     /translation="YLNESGSMATGWVTVSGKWYYTYNSGDLLVNTTTPDGYRVNANG
                     EWVG"
BASE COUNT         3256 a         2132 c         1627 g         3030 t
ORIGIN      
        1 caaaacactg ttttgaggtt gtggatagaa ctgacgaagt cagtaaccat acctacggca
       61 aggcgacgtt gacgtgattt gaagagattt tcgagtatga gtttattttt tacctgactt
      121 gtccatattc cagaagtctg tcacggctcc gcgtgaagca gatgatacga tgtgggcata
      181 tttaccgagg acaccacggc tgtaaagtgg tggcaaggtt gtttctgcct tgcgtttttc
      241 aagttcttct tcggatacgg ccatagaaat ttctttggta tcttggtcaa ccgtaacgat
      301 atcgccggta cggagatagg caattggtcc accatcctga gcttcaggag cgatatgtcc
      361 aacaaccaga ccataagtac caccagagaa acgtccgtcc gtcaagaggg ccaccttatc
      421 tccctgacct ttaccaacaa tcattgaaga aagtgatagc atctcaggca taccaggacc
      481 acctttaggt ccaacaaaac gaacaacgac tacatcgcca tcaacgattt catctgtcag
      541 aacggcctga atcgcatctt cttctgagtc aaagacctta gctggcccaa cgtgacgacg
      601 cactttaaca cctgatacct tggcaactgc accgtcagga gcaaggttcc cgttcaagat
      661 gataagcgga ccatccgcac gttttggatt ttcaagtggc atgataactt tttggcctgg
      721 agtcaagtct gcaaagtcag ccaagttttc agctacagtc ttaccagtac atgtgatgcg
      781 atctccgtga aggaaaccat ttgccaacaa atacttcata accgcaggga caccaccgac
      841 ttcgtagagg tcttggaaga catactgacc agatggtttc aagtcggcca agtgaggcac
      901 acgttcttga atcgtattga agtcctcaag tgacaagtca acatttgcgg catgggcaat
      961 ggcgagcaag tgaagagtgg cgtttgtaga accaccgaga gccatcgtta cagtgatagc
     1021 atcttcaaag gcttcacgag tcaagatatc tgatggtttg agaccaagtt ccaacatctt
     1081 aacaacagca cgtcctgctg cttcgatatc ttctttctta tcagctgatt cagctgggtg
     1141 agaggatgac cctggcaaac tcatccctag aacttcgata gcagttgcca tggtattagc
     1201 agtatacata ccaccacaac caccagggcc agggcaggca ttacattcaa gacgtttcac
     1261 gtcctcagct gtcatgtcac cgtggttcca ttttccgata ccttcaaaga cagaaaccaa
     1321 gtcgatatct ttaccatcaa gatttcccgg tgcaatagtt ccaccatagg cgaaaatagc
     1381 tgggatatcc atattagcaa tagcaatcat agatccaggc atgttcttgt cacagccacc
     1441 gatagcgacg aaggcatcca cgttgtgacc actcatagcc gcctcgatgg agtccgcgat
     1501 gatgtcacga gatgttagag agaaacgcat accaggcgtt cccatagcga tcccgtccgc
     1561 tacggtaatg gttccaaact gtacaggcca agcgcctgca gatttgacac cttctttagc
     1621 cagtttcccg aaatcatgca agtgaatgtt acatggtgta ttttccgccc aagtcgaaat
     1681 cactcccaca atcgatgttt caaagtcctt atctgtcata ccagtcgcac gaagcatagc
     1741 acggttaggt gatttaacca tgctgtcata aatgctactg cggtgacgtt tatctaattc
     1801 agtcatctta tccctcccat ttcagttttt actattatag cacaattttc gcatgaagaa
     1861 cagaataaaa ttcttgaatt ttcagaaaat tctatacaca tgtgaaatat ttaaaattaa
     1921 aaacaacaaa gcggattagt gcactttctg atgaccagaa tatgcttttt aatccgcttt
     1981 ctttaaataa cgtactgtaa tttttacaga aattctttca aataagtgta tttaacatct
     2041 atcttgcatt ataaatttct agaaccttct cttttatatt cgattcactc aaaccatact
     2101 cattaagaag ataatccatt ttccctactt gaccgaatct ttcttgaaca cccatccgat
     2161 gaatttttgt tattccatca tcagagaata attcacataa agcactgcca attccaccta
     2221 tctgattgtg gttttctaca gtaaatatag tttttccact taacattgtt tttatctgtt
     2281 ctggtatcgg tttgattcta aataaatcta tcacacctac tgaataacct aatttagaca
     2341 gttcatctgc aactcgaata cttggagcaa ccattatgcc agaagcaacg attacaagat
     2401 cttcaccatg ccttaactca atgtagcctt tagaaaaatc ttctccacct tgatacacag
     2461 gaactggagc ttttctaatt gttcgaatat attttagtcc ttttaagtct aatgtctggt
     2521 tcaatatttc acgaaattgg atatcatcag ttgcttcgaa aatgattgat ttaggaatta
     2581 aacgtaacaa tccaatttct tcaaatggca tatgtgttcc accattcatc tctgccgtta
     2641 ctcctgcatc tgatccaatc acagtggcat ccaattgtgc gtatccaaga gaaataaata
     2701 attgatcaaa tactcttcgt gaagcaaaag gaccaaatgt atgaagataa ggtctaaacc
     2761 cctgaataga caagcctgct gcaaggccga ccatttctgc ttccataatc ccaacattca
     2821 cataacggtc tccaaagtcc ttttcaagat tattagtagc catcgaactt gacaaatcgg
     2881 cttctaagac tactatatca gaatcacttt gattagcctc taaaaggaag tctctatata
     2941 catgccgtaa ttctttcgta cttctcatca ttctgtttcc tccaattcct gacttaatct
     3001 ttctacaact gaagttaaca tttgtttctc ctctacagta gggcgaagat gatgattgga
     3061 tttcatttct tccagctctt gaaccccttg acctttaata gtatctaata caatgcactt
     3121 aggtgatgaa ttatttgact gttttaattg gacaatccct tcataaattt ctctaatatc
     3181 tgaacccttg accctaatgg attcaaatcc aaatgctgaa aatttttcta cgaaatcacc
     3241 tggattacaa atatcctttg taaaaccatc taattgtttt ttgttatcat caacaaatac
     3301 aattaagttg gataactgtt gatgagaagc aaactgtata gcctcccaac attgtccctc
     3361 atttaactca ccatctccaa caatagcgta agtataaaag ggactctttc ttattctctg
     3421 accatatgca agtccagttg caacactaat tccttgtcct aaagagcccg ttgtcatatc
     3481 tatgcctggc gttagatttc tatcaggatg agacggtaat ttggttccat ttgtatttaa
     3541 agaatataag aattctttgt caaagaaacc attcaaatag agtgtactgt atagagctgg
     3601 tcctccgtga ccttttgata atatgaaata atctctatct cgtgctgcaa atatttctgg
     3661 agtcattggc attatttcac cataaagcac cgctaaaact tctacgatag acagacttcc
     3721 tccgtaatgt ccgaatccaa gatgattcaa tgttctaaga gtatttaatc ggatgttagt
     3781 cgcaaatttt cttaacccat cttctctatt tttacttaaa atcatccctt attcctccgt
     3841 tgcagatggc tttttaataa aggatactcc aaacataact gctagaataa gaacaagacc
     3901 aatcacaatg cctgcttgtg agccaaattg atttaacatt cctaaaataa ttcctgatag
     3961 accaaaatct gcatctgaga aagttgatcc ttggaaacca agtcctccca aaactggcat
     4021 taaaaagact ggaagaaaac tgattaaaat accttgtaaa aatgctccaa tagtggctcc
     4081 acgaacacca ccagatgcat tcccaatgac acctgcagtc gctccacaga agaaatgagg
     4141 cacaacacct ggtaagataa caaccgttcc tgaagcaatc ataattacca tacttactaa
     4201 accaccaaca aaactagaga taaatccaat tagaactgca ttgggtgcat aagtataaac
     4261 aatcggacaa tccaaagcag gttttgaatt aggtacaaga cgctctgaaa tacctttaaa
     4321 ggctggaaca atttcgccca aaataaggcg aacacctgct aaaataacaa atacccctgc
     4381 tgcaaattga cctgctaatt gtaaagcata aactagacca cttgtaccac tactgatttc
     4441 tttttctata tattctgacc ctgcaaagat agctacaata atgtaaataa ctgccatgga
     4501 taaagtaata ctaacagtac tatcacgtaa aaaagctaaa ctctttggaa atttaatgtc
     4561 ctctgttgat tttgatttgt caccgataag gctaccagta aaaccactca accaatatcc
     4621 caaagaactg aaatgaccta aagctacctt gtcatttcca gttaattgaa ccatatattt
     4681 ttgcacaaat gctggggaaa tactcataat aataccgagt gctaatcctc ctagtaagat
     4741 gagaggcaag ctagtaaagc cagcaactga taaaatgacc gcaatcatac atgccatata
     4801 tagagtgtgg tgccctgtta aaaaaatata tttaaatcga gtaaaacgag cgattaagat
     4861 attgaacacc atgcctgcaa acataatcat tgcagtagct gagccatatg ttgttaaagc
     4921 tacagctaca attgcttcat tattcggcac aacgccagat aaatgaaaag catgctcaaa
     4981 catggtacca aatggattta aagaattttg tacaattcct gcaccaccag atacaactaa
     5041 gaaaccaaca aaggtcttaa ttccaccttt aataatatca ggtaatttct tcttctgaag
     5101 aactaatcct aagattgcaa ttaaagctac taaaatagct ggtgtactaa caatatccaa
     5161 tatgaacttc atcatgacgc tagcctccta tataagtcct ttttcttcac aaagtttagt
     5221 aattaattct cgtagttcat ccatatcaat aatactattt aagatacgaa catctccaag
     5281 atgactagct gaatcagcta gatcacgacc aacaatccaa atatcagctg catttggatc
     5341 tgctccacct aaatcataat gttcaacttc tacatccgaa acattcaaat cactcaatac
     5401 agattcaata ttcatctgta ccataaaact tgaacctaat cctgaaccac aagctgtacc
     5461 aatttttaac attatctaat cctcctgttt aattatcatt ttaatgtcat catagttttt
     5521 tgatgatatt aaagtttgaa catgattttt atctcttaaa attgttgtta aatgtgacaa
     5581 agcctttaaa tgactctcat tatcaatggc tgcaatacaa atcaacaatc ttacctcttg
     5641 ttctggatta tccaataaat aaatcggttc ttccaaaact aacattgaca ttcctatttc
     5701 attcacacct tcatctggcc gagcgtgagg aattgctact cccttcccta aattaataaa
     5761 aggtccaaac tcttctactt tttgaatcat tgcctcaggg tagttctcag ttatcttatc
     5821 ttgatccaaa agcggtttag ctgctaaacg aatcgcctcc ttccatccta atttttgcga
     5881 actaacctga taggtttctt tggtaataag ttgttctagc actggtacaa tttcctttct
     5941 atcatttttt tggtaaagat aattctttaa cgccaatctt aattccaatt cttgtgtaat
     6001 aattccatat cttttgacaa tattcaggat ttgttcaatc tcaaaatctc catactctaa
     6061 attcggaaaa tcttttaaca ctagttctac tagttgtatt gcttgctctt cagtcatcat
     6121 aaccgaaact agataatttg gcttttctgt ctccaccttt atggtagaaa aaaccatatc
     6181 atagtcacta ctagctttca cctgtaaatc atcaatcttt gaggttccta taaactcaat
     6241 ttgaggaaat aatgctaata gattctcttt taacatcaat gaagaactaa caccattagg
     6301 acaaatgatt gctgctttat accatttttg aggcaaagta tctgctttct ttaaataacc
     6361 tccgaaatgg ataacaaaat atgctgtttc actatcaggt atgggattgt caatagcgtc
     6421 catcaagggc atcaaagaat ctttgactaa ttcaaataaa tcaggataat gttctttaac
     6481 atgcaataca tattcatttg aactaggtag gccgaacttt aatctatagt aagccggtat
     6541 aaggtggcgg cgaagatttt ctctcaatcc ttccctttgt ttaaaatgta acaaagaaat
     6601 atcttccatt ctacttataa tagcctctgt taattgatta aagtaaaccg gagcaacatc
     6661 tacttcacct tcaaagcaac ttgataataa aacggtgata tagcgataat catcctcaga
     6721 aaacaccgta tctataattc ccaaatcaac cactgtatcc aataaaatag tggttatatc
     6781 ttgaataaca ggagatacta atgtctctga aagacatact ctttcaacat ccctttgata
     6841 cctacacaga atgaatacta aaccgaaaag gtaaactttt aattgattaa caataggtac
     6901 tagctgtagc ttctcataat aatctttaac tacctgatca atcaaatcat aagttaatga
     6961 atacccccaa ctggataaaa cataatccaa accccaaatc cctatggagg attccagcaa
     7021 ctcactaacc atttgaaaag ctaagcggtg cttattccac tctgaaccgt gtaaagtata
     7081 accttttgct ctactgtacc ctagctccaa atcattatct aacataatct ttcttaatga
     7141 ttgaatatca gataaggttg tattcttact tactttcaaa aagtcttggt aatgactatt
     7201 cgatataaaa tctaatcggc aaaaagtgta aagatagatt aaagctaagc gagtcgactt
     7261 tggtaaaacc aattcatccg acttaataat atctgtcaaa gactgcttcg tacgatttga
     7321 taaactatag cgaccttgct ttttatccag cactatccct ttattagcta gataaggcac
     7381 taaataatct attccttctt tgacttcctt tataggtaag ctcaccttaa cagataattc
     7441 atataatgat agctcacaat gatccatcaa agtcatcaaa ataactagtg ctctataatc
     7501 aaacatttct cttcctttct aactacaatt atagtgtaaa aattataaga ataaaagagt
     7561 atttgagcac aatataatct caccttttaa aagaaattat tgggctgaaa gtttttagtg
     7621 attatttttc aactttctat tgactttata aattaaagtg atatcattta gatatcaaat
     7681 aacaggaggt cattcttatg actgaaaaac taatcaattc aaaaccaaat ggtgtattcg
     7741 cattgattct cattgagttg acaatcgtac ttggtatctt tatatttata atgggggttg
     7801 gttcggaaaa catttttgga attattatcg gacctttact aatcgtaatt gcaggtctag
     7861 ctcatgctgg tttaaaagtt gtcaaacctc aagaagctct ggttctgaca ctctttggta
     7921 actatacagg taccatcaaa gaacctggct tttactttgt caatcccttc agcgtagcag
     7981 tcaaccctgc aaaccacact cgacttggac aaagtggtga tgttagcaca aaatctcctt
     8041 ttttaggagc taaatcatca aatgacaatg atgtaaatct tgaaattggc aagaaacaga
     8101 tttccctcaa agtcatgacc ttgagcaatt ctcgtcaaaa aatcaatgat tgcttaggaa
     8161 accctgtaga aatcggtatc gcggtaactt ggagagttgt cgataccgct aaggcagtct
     8221 tcaacgttga taactacaaa gaatatcttt cattgcaatg tgatagcgcc ctccgtaata
     8281 ttgtccgcat ctatccttac gatgtgtctc ctaatgtgga tactacgggt gatgggcaag
     8341 cagatgaagg tagtctccgt ggctctagcg aaattgttgc taaccgtatt cgtgaagaaa
     8401 tccaaagtcg tgttgaggat gctggcttgg aaatccttga agcacgtatc acttacctag
     8461 cttatgctcc agaaattgct gccgttatgc ttcaacgcca acaagcatct gccattattg
     8521 atgcacggaa gatgattgta gatggtgctg taggaatggt tgaaatggca ctagaacggc
     8581 tcaatgaagg ggaattggta gaacttgacg aagaacgaaa agctgccatg gtttcaaatc
     8641 tccttgtcgt tctttgtggc aatcatgatg cacaaccaat tgtcaacaca ggaagccttt
     8701 actaaagatg gctgaagcta aaaaaaagca gatccccctt cgactctcaa caaagttata
     8761 cgctgcactc gcatcatggg cagaagacga ctttcgttca gtcaatgggc aaatcgaata
     8821 tctcctcaca gagtgtgtca agcaacggaa gaaagacgga aaatacgtat cagaaaccat
     8881 tgacgaacca tttgagattg atatttaaca ccttctcctg tctgccgtgt cggataggag
     8941 aattttttca tctttttttg tcaagtaact ttactttaca aaaaaaatgt gttatcctag
     9001 tatggttgat gaaaatcagt agattgaatc gaatataaat acctaaagga gaaatcaaaa
     9061 tggcagtacc tgcacgtcgc acttcaaaag cgaagaaaaa caaacgtcgt acacactaca
     9121 aagtaacagc tccatctgta aactttgacg aaactactgg agattactca cgttctcacc
     9181 gtgtatcact taaaggatac tacaaaggac gtaaaatcac taaagctgca tcagctgaat
     9241 aatagaaggg agataccatg cgcgtaaata ttacacttga acacaaagaa tctggtgaac
     9301 gcttgtacct tacttctaaa aacaaacgta acactccaga ccgccttcaa ttgaagaaat
     9361 actcaccaaa acttcgcaaa cacgttgtgt ttacagaggt taaataagca ttcaatacga
     9421 atcaatacag aagaaaaacg cttgatcagc gttttttctt tttgttaatt tcactacatt
     9481 gtaagggaaa tcattcgaat gactacattt ttcactacct tttttgaaat aagaatacgg
     9541 attcggacaa ttaaaagcaa gaggaactca aatgtaagtt ggggttcctt ttttgtatat
     9601 ttttcaaata acgcctctac actatttgta gcaaattcac caactacagt tgtatcttag
     9661 ttaaaataag ttagaatatg taagtgagta ccagatatac caagacatcg tcaccatcta
     9721 aggtatattc aaaatacaaa agttgaccaa ctagatttct gaatatcctt atatatccat
     9781 tcttaaaatt ggtttaaata gcgtagtctt ttaaactagt tttgagaatc caaaaaatct
     9841 tcctacatat gtaagaagat tttttagttc agaatgatta gatttagcta atggatacct
     9901 atcctaccca ctcaccgtta gcattgactc gatagccatc gggtgtagtc gtgtttacta
     9961 ataaatctcc tgaattatag gtatagtacc atttaccaga aactgtaacc caaccagtag
    10021 ccattgaacc tgattcattt aagta
//
LOCUS       DAVBEM010000064         9624 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVBEM010000064 DAVBEM010000000
VERSION     DAVBEM010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9624
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.064"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            360..947
                     /locus_tag="VQ548_001884"
     CDS             360..947
                     /locus_tag="VQ548_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654685.1"
                     /translation="MFVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNILSDEVLE
                     VVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVNTIHGNKQ
                     ANTFANFMTGAGISYMIGRIGTLLGGPWGAIIGGAYFGIQAYQSYLDSQSPYPYYITS
                     TYIHVAQKKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            complement(1034..1237)
                     /locus_tag="VQ548_001885"
     CDS             complement(1034..1237)
                     /locus_tag="VQ548_001885"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654686.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(1534..2238)
                     /locus_tag="VQ548_001886"
     CDS             complement(1534..2238)
                     /locus_tag="VQ548_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET2654687.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            complement(2308..4134)
                     /gene="glpO"
                     /locus_tag="VQ548_001887"
     CDS             complement(2308..4134)
                     /gene="glpO"
                     /locus_tag="VQ548_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HET2654688.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPILDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            complement(4176..5684)
                     /gene="glpK"
                     /locus_tag="VQ548_001888"
     CDS             complement(4176..5684)
                     /gene="glpK"
                     /locus_tag="VQ548_001888"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HET2654689.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            complement(5843..7270)
                     /locus_tag="VQ548_001889"
     CDS             complement(5843..7270)
                     /locus_tag="VQ548_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2654690.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLDSAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            7435..8307
                     /gene="hslO"
                     /locus_tag="VQ548_001890"
     CDS             7435..8307
                     /gene="hslO"
                     /locus_tag="VQ548_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HET2654691.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQERHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGAGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            8294..9274
                     /gene="dusB"
                     /locus_tag="VQ548_001891"
     CDS             8294..9274
                     /gene="dusB"
                     /locus_tag="VQ548_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HET2654692.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(9504..>9624)
                     /locus_tag="VQ548_001892"
     CDS             complement(9504..>9624)
                     /locus_tag="VQ548_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654693.1"
                     /translation="ASQWFKVSDKWYYVNGSGALAVNTTVDSYRVNANGEWVN"
BASE COUNT         2740 a         2186 c         1922 g         2776 t
ORIGIN      
        1 acgtctattt attttttatt gttttttatt gtagagcaga cccaagcgaa tgaacatagg
       61 ttgtaaaaag caaatgaaaa aactgcgagg ataatagctt ctgtgtctaa ataacccatt
      121 tcgagacctc ttttcaacaa caacaagcct gtagtttcga taacgatcaa acataaaaat
      181 atataaaaaa ttttcgcatt aagcatattg ttaccgcttt ctttttattt ggttttattg
      241 tataataaaa gttgaaaaaa atcaaaaata caaaggagtt tccgttatgt ctaagatgtt
      301 taaatgcatg tgtttgctag ttatgtctgt tttctgtatg tctagcattt ccccgtcgct
      361 tgtttgtttt tgctgatgat agcttatcgg caaactctaa agttgtatct ggtgaggctc
      421 agtttgagaa tggctcatca gtgcggttcg gagatacgca agtaaatatt ttaagcgatg
      481 aagttcttga ggttgtcaat ccagatggaa gtgtagacac tattgaacga cgtgctgacg
      541 gcgtctatat caatggggca ttttatatgg cttatcaaaa gaatgaaatc gacctaaata
      601 tatcttttag atcatacgat cctaatgttt ggaattacgt caacacaata catgggaata
      661 aacaagctaa cacattcgct aacttcatga ctggtgctgg aatcagttat atgattggta
      721 ggataggtac tttattgggg ggtccatggg gtgcaataat tggtggagca tattttggta
      781 tacaagctta tcagtcttac ttggattcac aaagcccata tccatactac ataacaagta
      841 cttatatcca tgttgctcaa aaaaaatgga agtttatcac tgaatactat agaaactcaa
      901 actatactgg gtatgtaaaa accgtaacaa cctacgtgaa tttctaaaat ataaaccctg
      961 cctagatata aaggcagggt ttatatttta gttaattgct caagtaattt gtaagcataa
     1021 tacttgcgaa actctatttg ttcaagcggt tcaaaagctc ttgtttttta tcctcaagct
     1081 cagctctcct ttgctcgatt tcttcacgtt tttgggcgat ttctgcttgc gcctcgggag
     1141 tttccaaagt gccttgtgac ttgtgaaatt ctactagcat atcaacgatt tttgggtcta
     1201 attcgttgac ataatcagga tttgaccatt tcggcacgtt gcttgcaggt gcttgctttt
     1261 tgccgccttt tttgggcgtt ttggcttgtt gttcagcttt ctgactgtag ttgacctcgt
     1321 ggaattttcg tgcttgatat gatgcgtttt attatgagaa gatttacttc attttttgct
     1381 gaaattgggc tcttgcccaa gctctatcaa cataattgtt ttctaatact caatgaaaat
     1441 caaagagcaa actaggaagc tagccgtaag ctgtacttga gtacggtaag gcgacgctga
     1501 cgtggtttga atttgatttt cgaagagtat aaactagaaa agtgagaata caagcactgc
     1561 caaggctgct ccgataacag ggcctacaac aggaatccaa gcgtaagacc agtctccgtc
     1621 tcccttgttt ggaattggca agatgctgtg catgatacga ggtccaaggt cacgagctgg
     1681 gttcaaggca taacctgttg tcccacctag tgatagaccg ataccgacaa tcaaagttcc
     1741 cactgcaaag gttccgatac ctgcctgaaa atcgtaaaga cccaaagcaa agattgtcaa
     1801 caccaaaaca aaggttccaa ggatttcgct aatcaagttt gatacagtat ccttgatggc
     1861 tggtccagta ctgaaggttg ccaggatatt gcctgcattt tcttctgcct catagtgagg
     1921 tttgaattgc aaccaaacca aaatctgacc cagcatggcc cctgcgaact gggctaagat
     1981 ataaggcaaa acggaagccc aaggcaaacc accttttaag gccacaccga tggtcacagc
     2041 tgggtttaaa tgagctggac tgagcttgcc agatacaaag actgcaaccg caactgcaat
     2101 cccccaaccc atagtaatca caatccaacc tgagctattg ctcttggttt taggaagaac
     2161 cacacctgca acaacaccat ttcctagaag aatcaggatt aaagtcccta gaaattctcc
     2221 aaataattca ttcatcatct ttctgtctcc attaaaaaga agggacgggc gacaaggaat
     2281 gctgccctcc acctctttta ttttttctta attttttaat tctgctaaat cgttgttagc
     2341 gagagctgct tcgacatcag cacggtaagt tgctttttct tcttctgtcc agtcatagaa
     2401 tcgtcccatt tcatccaaaa ttggctcaac gatgctatcc aagctatcac gcataaagag
     2461 catatggttg gtacgacgaa gaaggaagtc aactgggcta agagccaact cgttgcgcat
     2521 tgcatagtga agggacaaag tatctgccaa gctgagtcct ggcgcttgtt ccaagctgtg
     2581 agcaagtgca aagactttcg gtgcatttga accgtaaaga tttgccagat agtgagcttc
     2641 cttgctatcc aaaccacgtg atactccaag ttgcgcaaag gcttcgattt ctgaatccac
     2701 atttgctggg ttcaattctc cacctgaaac agggtaagtt ttagaattga tcaatttaaa
     2761 gctacggtca aattctgctt tgaggatgtc aaccacgcgc tccatagctc cttcagccat
     2821 cttacggtag tctgtgattt taccgccagc aagagtcaaa agaccattgt catcacggtc
     2881 caagctagac ccacgagaaa ctgcagatgg atccaaatgt ttctcagatg tgctactttc
     2941 aagcttgctg acagcagact caacatcttc acgtgttttt tctttggaga gataagattc
     3001 aacagtcgca atcaagttgt caaagctttc atcactgatg gtaccgttat ttccaccatt
     3061 atagtcagag gcactgttcc ctgcaatcaa tggacgaaga cctgcccagc tgctttcgat
     3121 atcatcaatg gtgatgttgg attctggaaa gcggttgttg acaatgccaa gtagataatc
     3181 tacatcttct tgagttactt ttggatgctc caaatcacct gtgtagtctg tatcagttgt
     3241 accaaagtaa gtcttgtttt cacgtgggag aacaaagacc atacgaccgt cacccaaacc
     3301 tgtgtcaaag taaactggct gtgaaacctt gattttgctt gaatccacta ccaagtgaac
     3361 tcccttagtt gggcgcattt gtgagaattg cgttccctta ttagacaaat tacgtacttt
     3421 atcactccaa ggacctgttg tattaataac cagacgggcc ttgatttcaa atacttggtc
     3481 tgtcaagaga tcacgagcta caacacctgt aatcttgcca ctttcgtcaa agaggaagcc
     3541 ttctgccttc acgtggttgg caatgagggc accgtcttgg ttggcacgtt tgatgttttc
     3601 aatcacgaga cgcgcatcgt tgttacggaa gtcaagatac actccacctc ctaccaagcc
     3661 ttccttcttc aagtttggct ggcgttccaa gacttgatcc ttgctcaaaa ccttgttcgc
     3721 agttggtgtg ttgctaacac ctgccaagag gtcgtacaag tccatggcta ctttaagacg
     3781 gaagaggcta aaggttgctc catcttcatc gtaaactggt aagagcattg ggtctggttt
     3841 tggaatgtgt ggagcgattt gttgaaccac tgcacgttca gaaaccgtat ctgagaccac
     3901 ttctacgtcg aattgtttaa ggtaacgaag tcctccgtga accaattttg ttgaacgact
     3961 agatgttcct tctgcaaagt cttgcatttc aatcaaacca gtctcaagac cgctagctgc
     4021 cgcctgcaag gctacaccag ctcctgtgat tcctccaccg ataatcaaga ggtccagggt
     4081 gcgttcctgc atttttttaa ttgacaattc acgtgttttc tttgaaaatt ccatatttac
     4141 acactttcta aataaatcgc tttattctgc cagtattagt cgtctacttc cgcaaagact
     4201 tgagttgctt tcacagcctt cttccagccc ttgtagagtt gttccttgcg agattcgttc
     4261 atagatggct caaagagttc tcctgtctcg ttcaagagtt tcaactcgtc caagtctttc
     4321 cagtacccta ctgacaaacc tgctaggaag gccgctccta gagctgttgt ttccaggttt
     4381 ttagcacgtg caatgtcaat gcctaaaata tccgcctgga actgcatgag gaagttgttc
     4441 atggctgcac caccatccac cttcagtact tgaatggcgg tctgagtatc cacttgcatg
     4501 gtgtcgatga tatcacgcac ttgataagca atagattgca aagtcgcctt gataaagtct
     4561 tctttgcttg ttccacgagt caaaccaaag acggaaccac gagcattttg gttccagtat
     4621 ggagcgccta gacctgtaaa ggctggaacg acataaactt catcgttgtt gtgagaatca
     4681 cgagcgtatt tttcagattc tggtgaattt tcaaccatgc gaagaccgtc acgaagccac
     4741 tgaatagcac ttcctgcgat gaagatagaa ccttccaagg cataataaac cttaccgttg
     4801 attccgtaac caatggttgt caagaggttg ttttcagaca actgcatctc ttccccagta
     4861 ttcatgatga tgaaagagcc tgttccataa gtattcttaa ccatacctgg ctcaaaagcc
     4921 aactgtccaa agagggctgc ttgttggtcc ccagccatac ctgagattgg cacctctcca
     4981 ccgtagaaat ggaatggagc tgtcttgccg tagatttcgg agttagaacg aacttctgga
     5041 agtatagcct tcggaatgtt aaggatttcc aaaatctcat catcccattt gagttcttta
     5101 atgttataaa gcatggtacg agctgcattt gagtagtcag tcacgtgagc cgcaccgtca
     5161 gtcaatttcc aaaccaacca agtatcgata gtaccaaaga gcaattcccc tttttctgct
     5221 cgctcttgag caccttctac atgatccaaa atccaacgaa ccttggtagc agagaagtaa
     5281 gcatcaataa tcaaaccagt cttttcatgg aatttttcca cataaccttg gctttttagt
     5341 tgctcagcca aaggtgctgt ctggcgtgac tgccaaacga tagcattgta gataggaagt
     5401 cctgttttct tatcccagac aaccgttgtt tcacgttggt tggtaatccc gattgcctcg
     5461 atttgatttg gcttgacacc actttcgatg aaagcacccg caataactga ctgaacagag
     5521 ttccaaattt cattggcatt gtgctcaacc caacctgcct gagggaaaat ctgggtaaac
     5581 tctttttgac tcgagctaac cttttcccct tttttgttga aaatgatggc acgagaactt
     5641 gtagttccct ggtcaatggc catgatgtat ttttcttgtg acatgtactg tcctcctgat
     5701 aaagatcttg aggtgtttcc tctttacact tactagtata caaaataaag cgctttcttg
     5761 tttatcaact ttttttaatt tttaaaaaaa tgtgaggaga ttgtgtgaat ttcacaaaaa
     5821 agacctagat taaccaagcc ttttaagtga ataataactg acgaatccct gccaaatctt
     5881 ccatatccaa gtcgtttttt aaataataga ctggtgtctg ttccttctta tgaatcgggt
     5941 tattggtaac cagcaaatca taatgccgac tagggtcata agcttcaatg gtaataaaac
     6001 gattgtattc caaataccgt ttcaaaatgg ctgccatcct tgaaaagaca agaaaaccag
     6061 atgtcaaatc cagaccaatc cgcatatgct ggccaccgtt ttcagccata tattcgatta
     6121 actggagcca ttcccagaga atcttcttat ctaaatctgt cccctgttga aaagcaggta
     6181 gagcatgaaa aatctcctct gctgtctctt taaaatcatg ttccatcagt aaatatggat
     6241 gacgattctc taactggtac ttgtagcgat cctgtaaaat atagccctta tagagataga
     6301 cttgagcaca aagctgactg agttcatagg tgacatggtc ctctgtataa tcccccaata
     6361 gttcctcctt cttcatttct tgaatcaatt gcgtcagtaa atctgccaac tgccctccaa
     6421 aaccaagaat atactccata gtatgaagag gaagaatgcg atgagatagg agaaaagaga
     6481 agaatatcat catctcacca tcctcaactc ctagtggaat atgttgccca gcaaaaaagg
     6541 acggaacctt tctcagcaaa cgaagataaa agatattgtc aaaataccct cgcattttct
     6601 cttctatgac ttgaaactga caagcattga cccgaagacg ttgttgactg atgtgagccc
     6661 agagaaccaa gtccaatttc tgccccgcag acaaacttgc accgcagatt tcctctaaat
     6721 tggcaatctc ctgttttctc tctggtttct gcatgtgacc ttcccattcc tgactcgacc
     6781 agacctttcg gaaaagacag aaatagaaat agcgaatctg atgctctgga cctctccagc
     6841 gtccattttg gatggataaa tcaaattctg acaaaatctg atttaaacca gccaagtgac
     6901 gaccaagcgt agcctcgcta atcaccaatt cttgagccag ctgatgggct aaaaactgtt
     6961 ggtggtagag aagataaacc aaaatctggt atttaacagc actatccaaa aacaagctcc
     7021 gaatatctct ccccttggta gctgcaccga tagacagacg cagattttca tcttctgagt
     7081 gaatagtcag ttctaagcca ctatccaaag ccttgtcatt gagcagggtg acatatttgg
     7141 ttagggttgc ttttgaaaat cctgtttctt ccattacagc cttgacggtc gtctgagact
     7201 cttgtaatag aaaggaaagg attgaaaatt gaccacactc ggctttctcc atcaaatctc
     7261 ctaaatacat ttgttacccc tttcattttc taccttaagc atagcataaa tcttacaaat
     7321 gctgaaataa tctgtttctc tttttatttt catgctgatt tcctggtcca ttatcctgaa
     7381 aatcagtaaa cacacggctc cccctttggg catttttatg ctaaaatagt agctatggat
     7441 aaaattatta aaactatatc agaaagcgga gcctttcgtg cttttgtcct tgatagcacg
     7501 gaaaccgtcc gcactgctca agaaagacat caaacccaag ctagctcaac tgtagcgctt
     7561 ggtcgaactc ttatcgctag ccagattctc gcagccaatg aaaaaggaaa taccaaactt
     7621 acagttaagg tgttgggctc tagctctcta ggtgctatta tcaccgtcgc tgataccaag
     7681 gggaacgtca aaggctatgt tcaaaatcct ggtgttgaca tcaaaaagac tgcgactggt
     7741 gaagtcctag tcggaccttt tgttggaaat ggtcaattcc tcgttatcac agactacggt
     7801 gctggaaatc cttacaactc tataactccc ctcatctctg gagaaatcgg tgaagacctt
     7861 gccttttacc ttactgaaag ccaacaaacg ccttcagcgg tcggcctcaa tgtccttttg
     7921 gacgaggaag acaaggtcaa ggttgcaggt ggtttcctag ttcaagtctt gccaggagcc
     7981 aagaaagaag agattgctcg ctttgaaaaa cgcatccaag aaatgccagc tatctctact
     8041 cttctcgaaa gcgacgacca tatcgaagcc ctcctcaagg ctatctacgg ggacgaagcc
     8101 tacaagcgtc tttctgaaga agaaatccgt ttccaatgtg actgtagcca tgaacgcttt
     8161 atgaacgctc ttgccagcct tccaagctca gacttacagg aaatgaaaga ggaagaccac
     8221 ggggcagaaa tcacttgtca attctgccaa actacttaca actttgatga aaaggacctg
     8281 gaggaactca ttcgtgacaa atcttaatac accttttatg attggcaata ttgagattcc
     8341 caatcgtacc gttttagcgc ctatggctgg cgtgaccaac tcagcctttc gtaccatcgc
     8401 aaaagagctc ggagctggac tcgttgtaat ggaaatggtc tctgacaagg gaatccaata
     8461 caacaacgaa aaaaccctgc acatgcttca tatcgatgag ggcgaaaacc ctgtctctat
     8521 ccaacttttt ggtagcgatg aagacagcct agcacgcgca gcagaattca tccaagaaaa
     8581 caccaagacc gatatcgtcg atatcaacat gggctgccct gtcaacaaaa tcgtgaagaa
     8641 cgaagctgga gctatgtggc tcaaggatcc tgacaagatc tactctatca tcaacaaggt
     8701 ccagtctgtc cttgatatcc cacttactgt caaaatgcgt accggatggg cggacccatc
     8761 tcttgcagta gaaaatgccc tcgctgctga ggctgcaggt gtttctgccc tcgccatgca
     8821 tggccgtacc cgtgaacaaa tgtatactgg ccacgcagac cttgagaccc tttacaaggt
     8881 tgcccaagct ctaaccaaga ttccattcat cgccaacggt gatatccgta ctgtccaaga
     8941 agccaagcaa cgcatcgaag aagttggtgc tgacgcagtc atgattggcc gagctgccat
     9001 gggaaatcct tacctcttca accaaatcaa ccattacttt gaaacaggag aaatcctacc
     9061 tgatttgacc tttgaagaca agatgaagat cgcctacgaa cacttgaaac gattgattaa
     9121 cctcaaagga gaaaacgtcg cagttcgtga attccgcggc ctcgctcctc actatctccg
     9181 tggaacatct ggcgctgcca aactccgtgg agccatttcg caagctagca ccctggcaga
     9241 gattgaagcc ctcttgcaat tggagaaggc ttaatagttt aaaacccgta actctcttaa
     9301 agagcctctt gaatgccgcc attctttcct catcaaaaaa actccgtagt ctctagcgct
     9361 ataaatccgg ctagagatta cagagttatt tttttatcta aacttcctac aagggtatat
     9421 tatctactga aaggatatgg tatttgtagg gaatacttta aagagttctt acaggaagtc
     9481 agtattaact agttatatta ggtttagttt acccattcac cattggcatt gactctatag
     9541 ctatctacag ttgtgttgac tgcaagggca cctgagccat tgacatagta ccatttatct
     9601 gatactttga accattggct tgct
//
LOCUS       DAVBEM010000065         9472 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVBEM010000065 DAVBEM010000000
VERSION     DAVBEM010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9472
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.065"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            150..686
                     /locus_tag="VQ548_001893"
     CDS             150..686
                     /locus_tag="VQ548_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HET2654694.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            737..823
                     /locus_tag="VQ548_001894"
                     /pseudo
     CDS             737..823
                     /locus_tag="VQ548_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(892..1107)
                     /locus_tag="VQ548_001895"
     CDS             complement(892..1107)
                     /locus_tag="VQ548_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HET2654695.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            1205..1525
                     /locus_tag="VQ548_001896"
     CDS             1205..1525
                     /locus_tag="VQ548_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654696.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(1556..1894)
                     /locus_tag="VQ548_001897"
     CDS             complement(1556..1894)
                     /locus_tag="VQ548_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654697.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(1906..2625)
                     /gene="trmD"
                     /locus_tag="VQ548_001898"
     CDS             complement(1906..2625)
                     /gene="trmD"
                     /locus_tag="VQ548_001898"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HET2654698.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(2615..3133)
                     /gene="rimM"
                     /locus_tag="VQ548_001899"
     CDS             complement(2615..3133)
                     /gene="rimM"
                     /locus_tag="VQ548_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HET2654699.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKRYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(3164..3952)
                     /locus_tag="VQ548_001900"
     CDS             complement(3164..3952)
                     /locus_tag="VQ548_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2654700.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            complement(4529..4768)
                     /locus_tag="VQ548_001901"
     CDS             complement(4529..4768)
                     /locus_tag="VQ548_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HET2654701.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(4788..5060)
                     /gene="rpsP"
                     /locus_tag="VQ548_001902"
     CDS             complement(4788..5060)
                     /gene="rpsP"
                     /locus_tag="VQ548_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HET2654702.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            5230..5439
                     /locus_tag="VQ548_001903"
     CDS             5230..5439
                     /locus_tag="VQ548_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654703.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            5918..6139
                     /locus_tag="VQ548_001904"
     CDS             5918..6139
                     /locus_tag="VQ548_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654704.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            6222..7025
                     /locus_tag="VQ548_001905"
     CDS             6222..7025
                     /locus_tag="VQ548_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET2654705.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQSSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(7081..8622)
                     /locus_tag="VQ548_001906"
     CDS             complement(7081..8622)
                     /locus_tag="VQ548_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2654706.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DLPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(8624..9106)
                     /locus_tag="VQ548_001907"
     CDS             complement(8624..9106)
                     /locus_tag="VQ548_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET2654707.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(9106..>9472)
                     /locus_tag="VQ548_001908"
     CDS             complement(9106..>9472)
                     /locus_tag="VQ548_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="50S rRNA methyltransferase"
                     /protein_id="HET2654708.1"
                     /translation="KLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALELAELLKNI
                     KKSSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGTDIDAACGQ
                     LLFNTMKRDRQKAVAAVNP"
BASE COUNT         2796 a         2028 c         1698 g         2950 t
ORIGIN      
        1 attttcgaat caacaaaaaa attatccaac ttgactagtc acgaaaatcg gctgttacag
       61 tttttgttac cttgttttta aaaaatggtt gacatcgact cctatatgag tataatagtt
      121 atcatacatt agaaaagagg ttaactattt tgaaaaaagc tcacgtttat gctatccctg
      181 ctattggggc tgctctcatt gctgctttgg cacaaatcag tcttccaatt ggacctgttc
      241 ccttcactct gcaaaacttt gcaatcggct tgattgctac tgtctttaga ccgagagagg
      301 ctgtactttc tgctggactc tatcttcttc taggtgctat cggtcttcct gtctttgcag
      361 gaggtggagc tggttttcag gctttagttg gccctactgc aggctatctt tggttttatc
      421 tcgtttactc tggacttact tcctctctaa ccaacagcaa gagtggtgtt gttaagattt
      481 ttcttgcaaa cctcttgggt gatgcccttg tctttgtcgg cgggattctc agcttgcatt
      541 tcctagctgg aatggcattt gaaaaagctc ttgctgtggg ggttcttccc tttatcattc
      601 cagaccttgg caaacttctg gctattagtt ttattagccg tcccctactt caacgcctta
      661 aaaatcaggc ttactttact aactaaaaaa ggatatcgag ttatcatgac tcaatatcct
      721 tttcttttat tttgaaaact tatactcaat gaaaatcaaa gagcaaacta gaaagctagc
      781 cgcaggctgc tcaaaacact gttttgaggt tgtggatgaa actgacgaag tcagtaacca
      841 tacatacggc aaggcaaagc tgacgcggtt tgaagagatt ttcgaagagt attagttgcc
      901 tttaaaggca tccaccatcg tttgaaattc ttcatttgag agagtaatcc ctttgcccat
      961 tttagtatgg tctggactcc aagcacgaat atcaaacttt gcaggggcac cattaaagct
     1021 cacacggtta atttccttgg tccaaccttt ttcgttttca gaaagagtca acaagtgctc
     1081 ttcgatttca aatgtaaatt ctgccatttt cttctccttt tttagtttca ttagtttatt
     1141 cgtaaaatct tgtagatttt aggaaaattt tatataatat tgatataaaa gaagggaggc
     1201 caatatgaga cataaattcc agcaagttct aaataaaata catgattttt taaatggata
     1261 tgaccaacct gaccagactg aaaccaactc ccttacagcc actattgaag aggctatcca
     1321 gaaacaaacc gctgttcacc ttatcttgtc tgagacaagt tttacaggtg atatcatcaa
     1381 atatgatcag caaggccagc aaattatcgt gaaaaatttt gccaaaaatg tgagccggat
     1441 tatccgtata agcgatattc aacgcctgcg atttgtcccc tcaactgtcc aaacagccca
     1501 aaaaaataga tttaagaaag agtgagatgt agttgcttca tcccactctt ttttcttagc
     1561 gaatttgttc aaaatgtaaa tgaactgcaa tatgatctcc ataaccactt ctttccaagt
     1621 cacgttgtaa acgataggaa atgtagtgtt ctgcaatggt aatgtaacct gcgcccaata
     1681 aacgatgttc aaccatagat tgaatcatac tgatagtcgc acgttccacc ttggcttctt
     1741 gtaaatccaa aactaccttc ttagtgactt gagcaagatt ttgacgcaaa tcatctgtca
     1801 aaacataaac agtttgggct gccttcaaga tggcttggta aatcttatct ggattaaatt
     1861 cagcaatttc gccattacgt ttgattactt gcataggttt ctcctttatt ctttgttttc
     1921 tttgatttct gccagcattt tttcttcttc tactgtcagt tgataatgtt caagtaaatc
     1981 cggtctgcgc tcgtaggttt tctttaaact ctcgtacaat cgccactgac gaatcttttc
     2041 atggtggcca ctcatcaata catctggcac gaccatgcct cgataatcat agggacgtgt
     2101 gtactgagga tattctaaaa gacctgaaga aaaactatca tcttggtggc tagactcctt
     2161 gccaatcact tctggaatca ggcgaactgt agcatcaatc atggtcatag ctgccaattc
     2221 tccaccagtg aggacatagt cgcctaggga aatctcatct gttaccaagg tcttaatgcg
     2281 ctcatcataa ccctcatagt gcccacagat aaagattagc tcttcctctt gagccaaatc
     2341 ttcagcataa gcctgatcaa actgctttcc agcaggatcg aggagaataa cgcgcggatt
     2401 tttcttttca atagcatcaa aggaatcgaa aataggttgt gctctgagca acatgccctg
     2461 accgcctccg tagggctcat catctacatg acgggccttt tcagcatttt ctcgaaaatt
     2521 atgatactgg atatccaaga gccctttttc tcgagccttt ccaacgattg agtgctccag
     2581 tggagaaaac atctctggaa agagggttaa aatatcaatc ttcatcgtct aacccttcta
     2641 agatttccac atcgacccgt ttatttggaa tatcaacatt gagaaccact ggtgggatat
     2701 aaggtaaaag caaatcacgt ttgccttttc gtttgaccac ccagacatca ttagcacctg
     2761 gttgcaggat ttccttgatg gttccaacca agctatcacc ctcatagact tccaaaccga
     2821 taatctcgtg atagtaaaat tcaccatcgt ctaggtcatt caaatcttcc tcagcgacct
     2881 tgagactata tctcttgtac ttttcgatag tattgatatg gtacatatct ttgaatttaa
     2941 taatgtcaaa gttcttctgt ttacggtggc tagcgatggt cactgtttgg acaaactgat
     3001 ctttttcatc aaacaaagcc agctcagctc cttttttaaa ccgttcttct gcaaaatccg
     3061 tcacagacaa gactcgcatc tcaccctgta atccctgcgt attaacgatt ttcccaacat
     3121 taaagtagtt catcttgtct cctgtaatct ccttttttcc atcttattct gacaattctc
     3181 gaataatagc cgcaattttt tccgattctg accattgtaa ataatggtga ttccctccta
     3241 aaatgagttt agtattggaa gtccaatatt ctgattctct gtactctttt tctctataag
     3301 gctgacaaaa aacaaataca ggaatatgag cttctataga tacatcctca aaatcttcct
     3361 cagtaatctc tccagatatc tgaaattctg gatcttgatt ttccaactct aagccttttt
     3421 cttgcattaa ttcccagatt tttttattcg tttcaggact aaatgttgct tgagttaagt
     3481 tcttaaaata aagttcagga ccacactcgt caatcagcct catctgctct tccatttctg
     3541 gataaggatt ttctgaaaaa tcagcaaaca tgactttttt agttgtcggt tcaattgcta
     3601 ctaaagtctg acgcttaatt ggtttctcga gtaatttgca agctaaaatt ccactccaac
     3661 tatgtgcaca aagtatatat tcagaaattc ctaattcttc aagtacttca taaaccgcat
     3721 ctgcaagatt atctagattt tttccagctt ggtcatgaat cggactccta cctgtgttcg
     3781 gaaaatcaat tgtcaaataa ccaattgtag gaggaggttt ttcaagtata agtgaaaaat
     3841 tttcataact tggtagcaaa cctgctccgt ttagacaaac tagcactttc ttttgctttt
     3901 gataagtaac agagaggcta ccaatttctg tagatacttc aaacctcttc ataaagaaat
     3961 ccactcattc tatataatga attattaaaa atccttatct tttattttat cacgttccaa
     4021 ggattttctc aagttggagg aaggggacaa catctctact ttcccttcaa aaatccttcc
     4081 aaatcatgtt tatgttggta attaacggct gcggttttgt ctttctcaaa gacagtcttg
     4141 gtaaggtcaa tatgattaat agctacgatt gcgacggtgt agtaaatgat atcagccagt
     4201 tctctggcaa gttcctcgtt cgaatcctat cccttctttt cgaccagagc gcctattcaa
     4261 aacctcggct acttctccga cttcctccac taacttcata aagagacctt catcagtccg
     4321 agactgctgt taatgttcga ttaagtagtc ttggaattgc ctaaacgttc aatcttttat
     4381 agtatattga aactagaata gtacaccttt acttctaaaa cattgttaga aatcgatttg
     4441 actgtcctga tcgatttgtc ctgttcttgt ttcattttac tatatcttct attccacaca
     4501 aaaaagcgag acatccgtcc cgcccttctt atttttcgtc aataacgatt cttacttttt
     4561 tgtattcagt tgggacagag tagacaatcg ttcttatcgc agaaatagtg cgacccttac
     4621 gaccgattac acgacccaca tcgctttgat caagattcaa atgatattcc aaaaattctg
     4681 gtgtatcctc aatcttgata gttaaggcat ctggttgtga aattaagggt ttcacaatcg
     4741 caataatgag attttcaatc gtatccatct gtcaacctac tttaaactta ttttgaaaat
     4801 ttagaatcgt ggaatttttt caatacgcct tcttttgaaa ggatgttacg tactgtgtct
     4861 gaaggttgag ctccattagc caaccatgca agaacgcggt cttctttcaa agttacttgg
     4921 ttttcagcaa caagtgggtt gtaagttcca actgtttcga tgaaacgtcc gtcacgtggt
     4981 gaacgtgaat ctgctacgtt gatacggtag aaaggttttt tcttagaacc catacgagtc
     5041 aaacggattt taactgccat ttttaaagtc tcatttcttt aattttttat ttcggtgaaa
     5101 tagctgagct atttagcaca tgttctatta tagcagattt ctggcatgtg tcaagaaaaa
     5161 aacttgacag actataaatt tcttaaagta tttagaaatt tgttagaata ggaaataaat
     5221 gtttgaaaga tgctatccgt gaatactatt ttagaaaaat tttataaaga acaccaagtc
     5281 aaacccttca tatcgcctga acgagagttg gatacttggc ttctaagtcc caagcccgtt
     5341 cccaagcgaa atatggactt attagtagat gattcactag caggagatat cattttacta
     5401 tggagaatcc agtttggtac ttttaccact gaaacatgat tttaaaaact cccattcgaa
     5461 tatgattcaa aattcgctta gaatcaatgt tttcccgctt tttcaaaaaa taaattttca
     5521 tctaatttaa ataactttca attaagtgtg aattttgctt aaaatcatta aaaagcaccc
     5581 catggtgtga accatgaagt gttgtaaatg ctgtgttgta gctagttctt agcgtttaga
     5641 gaactggcta gctttacgag ctttcttaag atctggtttc caaaatactt tgagtacact
     5701 tatggtattg atgcccctaa acatctaaaa actctggtag aaaaagggta tgctcttgtc
     5761 gaaacttctt ttgactcact tgaccatcta aataatacca tgaaaaagaa tatcctgaag
     5821 aagaagggag ttactggact ttctaaaatg aaatcttgcg acctggatca agcccttcat
     5881 gagcattttt cagaagaaga attagctggt cactttcatg tccttctatg gactttttta
     5941 caatggcatt gctatcacac ccaataccta tctaagcgcc tggttcgtaa actttattgc
     6001 agctcttcct ctaaatttcc taattgttga accaattgcc cgttttatac taagttcttt
     6061 tcagaaacca tttactgggg aagaagttga agaagttgaa gattttcaag atgatgatga
     6121 aatcccaact attatctaag ccagttctgt aaactactaa tatttgaaat ccacttcttt
     6181 ttagggtaca atggtataaa tgaatttttg agaggatcag aatgaaaaaa ctagcaaccc
     6241 ttcttttact gtctactgta gccctagctg ggtgtagcag cgtccaacgc agtctgcgtg
     6301 gtgatgatta tgttgattcc agtcttgctg ctgaagaaag ttccaaagta gctgcccaat
     6361 ctgccaagga gttaaacgat gctttaacaa acgaaaacgc caatttccca caactatcta
     6421 aggaagttgc tgaagatgaa gccgaagtga ttctccacac aagccaaggt gatattcgca
     6481 ttaaactctt ccctaaactc gctcctctag cggttgaaaa tttcctcact cacgccaaag
     6541 aaggctacta taacggtatt accttccacc gtgtcatcga tggctttatg gtccaaactg
     6601 gagatccaaa aggggacggt acaggtggtc agtccatctg gcatgacaag gataagacta
     6661 aagacaaagg aactggtttc aagaacgaga ttactcctta tttgtataac atccgtggtg
     6721 ctcttgctat ggctaatact ggtcaaccaa acaccaatgg cagccagttc ttcatcaacc
     6781 aaagctctac agatacctct tctaaactcc ctacaagcaa gtatccacag aaaattatcg
     6841 aagcctacaa agaaggtgga aaccctagtc tagatggcaa acacccagtc tttggtcaag
     6901 tgattgacgg tatggatgtt gtggataaga ttgctaaggc cgaaaaagat gaaaaagaca
     6961 agccaactac tgctatcaca atcgacagca tcgaagtggt gaaagactac gattttaaat
     7021 cttaaaaacc aaaaaaatac agtatccaca ttcggtactg tatttctttt actctcattc
     7081 ttaagttaaa ttattaaaat cccatatttg gtctatccag ccttcataaa agtctggctc
     7141 gtggcagacc ataaggatag atcccctata ttctttgaga gcgcgtttga gctcatcctt
     7201 tgcatccaca tccaaatggt tggtcggctc gtccagcact aaaacgttgt tttcacgatt
     7261 catcaagaga cagaaacgaa ccttggcttg ctctccccct gataatactt gaatctggct
     7321 ttcaatatgt ttggttgtca aaccacaacg ggcaagggct gcacggactt ctgcttgatt
     7381 aagggcagga aaggcattcc agacagcttc aagaggagtt tggcgattac cgccttctac
     7441 ttcctgctca aaataaccaa gttctaaata atctccacgc tccacttccc cagcgattgg
     7501 cgagataatg cccaagagac tcttcaagag agttgttttt ccaataccat tagcaccaat
     7561 aatcgcaacc ttttgattgc gttcgaaggt aagatttaaa ggcttagtaa gaggaaggtc
     7621 gtaaccaatt tgcaagttct tggcttggaa gataaagcgc cctggtgtac gagctggttt
     7681 gaaatcaaag gatggttttg gtttctcact ttggagttcg ataatatcca tcttatccaa
     7741 tttcttttga cgagacatag ccatattacg agttgcaaca cgggctttat tacgagccac
     7801 aaagtccttg aggtctgcaa tctctttctg ctggcgttcg taggctgcct ctagctgaga
     7861 tttcttcata gcataaactt cttggaactg gtagtagtca ccagagtaac gcgtcagctg
     7921 ttgattttcc acatgataga caatattgat aacgtcattg aggaatggaa tatcgtgcga
     7981 aatgagaaca aaggcattct catagttttg gagatagcgc ttgagccaat caatatgctc
     8041 agcatccaag tagttggtcg gctcgtccaa cagcaagata tcaggctttt caaggagaag
     8101 ttttgccaaa agcaccttgg ttctttgccc acctgacaaa gaagttacat ccgtatccat
     8161 gccaaagtcc ataacaccaa gagcacgcgc tacttcgtca atcttagcat ccaaggtata
     8221 gaaatcacga ctctccagac ggtcttgaag ttctcctact tcttccatga gagcatcaac
     8281 atccgcaccg tcttcagcca tttccatata gaggtcattg atacgagctt cagctttgaa
     8341 aagctcatca aaagccgtac ggagaacatc acgcaccgac tgtctttcag caaggacaga
     8401 gtgctgatcc aagtaaccag ccgtcacata tttggaccac tcaacctttc cttcatctgg
     8461 cagcatttta ccagtcacga tactcataaa ggttgatttt ccttcaccat tggcaccgac
     8521 caggccgata tgttctccct tgaggagacg gaaggacaca tcttcaaaaa ttgcacggtc
     8581 accaaaaccg tgactcagat ttttaacttc taaaatactc attttaattc cttatcttgt
     8641 ttttatgtaa tcgtttataa aggagccaag ccagatagcc acccaaagtg ttggtccaca
     8701 aatcatcaat ctcaaagacg cgattgaaat caaagaaaaa gtccaagatt aattgcgtac
     8761 actcgattcc aagactcaca agaaaactaa aaagaaggac cttttttgtt ttccgcaaat
     8821 ttggaaatag ataaaggagt tggaaaatca gaggaaaaaa caagaagaca ttgaggatat
     8881 tttgtaaaaa aatccaacat aattgtccaa tgtcactcac ttcgcccagt ttccagagag
     8941 aattgaaagg agtcaaaaga aaaaccaggc gtccaagatg ctgaatatct ggagttccca
     9001 ctcccacggt agattgttct tgaggagtaa agcaaaaata gacaatgcaa atgctataga
     9061 aaatgactcc ccagaccaaa atatgattat aagtcttctt catcattaag gatttaccgc
     9121 tgcgactgcc ttctggcggt cacgtttcat tgtgttaaag agcaattgtc cacaagctgc
     9181 gtcaatatct gtaccatgct cttgacgaac cacacagttg cccccttttt tcttaagcgt
     9241 atcatagaaa gccaacacgc gctctttggg actacggcta tattggtcat gctcactaac
     9301 tgggttataa ggaatcaagt ttacataaga cgatttcttg atgttcttga gcaattcagc
     9361 caattccaag gcttgttcca caccgtcgtt gacttcatta agcatgatat attcaaaggt
     9421 tacacgacgg tttgttgtct caatgtagta ttcaatagca gcaaagagtt tt
//
LOCUS       DAVBEM010000066         9149 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVBEM010000066 DAVBEM010000000
VERSION     DAVBEM010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9149
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.066"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            226..6657
                     /locus_tag="VQ548_001909"
     CDS             226..6657
                     /locus_tag="VQ548_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HET2654709.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VVDKETENKEKHEDIHNAIETSQDFKEKKTAVIEGKEVVSKNPVTDNNTSNEEARIKE
                     DSNQSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPYGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANHADEKG
                     MISYYLVDPDKDASKYEKLGEISEDKLKNAKSPEENTNNNQAKDEDSKPDEKSSVEGE
                     ASLEINKTISTIREFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIAY
                     DDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIEI
                     KATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKET
                     KAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGY
                     ALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQ
                     AVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKS
                     NVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWE
                     LRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDG
                     NVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRN
                     NGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTG
                     EVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKD
                     AGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQ
                     REDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVG
                     IFLGLKKKNQD"
     gene            complement(6948..7294)
                     /locus_tag="VQ548_001910"
                     /pseudo
     CDS             complement(6948..7294)
                     /locus_tag="VQ548_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7389..7574)
                     /locus_tag="VQ548_001911"
                     /pseudo
     CDS             complement(7389..7574)
                     /locus_tag="VQ548_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            7602..7829
                     /locus_tag="VQ548_001912"
     CDS             7602..7829
                     /locus_tag="VQ548_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2654710.1"
                     /translation="MRERLLTQPLLHADETSYRVLESHSHLTYYWTFLSGKVENQAIT
                     LYHHDQSRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            7905..8457
                     /locus_tag="VQ548_001913"
                     /pseudo
     CDS             7905..8457
                     /locus_tag="VQ548_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            9040..>9149
                     /locus_tag="VQ548_001914"
     CDS             9040..>9149
                     /locus_tag="VQ548_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HET2654711.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIV"
BASE COUNT         3433 a         1311 c         1791 g         2614 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggaag ttaaataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taaccacagc tgcagttatt ttagcagcct atgcccctaa tgaggtagtc
      301 ttagcagaca catctagctc tgaagatgct ttaaacatct ctgataaaga aaaagtagta
      361 gtagataagg aaacagaaaa taaagagaaa catgaagata ttcataatgc tatagaaact
      421 tcacaggatt ttaaagagaa gaaaacagca gtcattgagg gaaaagaagt tgttagtaaa
      481 aatcctgtga cagacaataa cactagcaat gaagaagcaa gaatcaaaga agattccaat
      541 caatcccaag gagatcatac ggactcattt gtgaataaaa acacagaaaa tcccaaaaaa
      601 gaagataaag ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc
      661 aagcaactat ccaatcttaa gaatacaaaa gttttatata cttatgatag aatttttaac
      721 ggtagtgcca tagaaacaac tccagataac ttggacaaaa ttaaacaaat agaaggtatt
      781 tcatcggttg aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt
      841 ggagttgagg aagctattga ttacctaaag tctatcaatg ctccgtttgg gaaaaatttt
      901 gatggtagag gtatggtcat ttcaaatatc gatactggaa cagattatag acataaggct
      961 atgagaatcg atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaagga
     1021 actgataaaa attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt
     1081 ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg
     1141 catattgcag ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc
     1201 atagatggaa ttgcacctaa tgcacaaatt ttctcttaca aaatgtattc tgacgcagga
     1261 tctgggtttg cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac
     1321 gttgatgttg tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat
     1381 tggcaagcta ttcgggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac
     1441 tatgcgactt ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg
     1501 accgacactg gaaatgtaac acgaactgca gcacatgaag atgcgatagc ggtcgcttct
     1561 gctaaaaatc aaacagttga gtttgataaa gttaacatag gtggagaaag ttttaaatac
     1621 agaaatatag gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa
     1681 gctcctagta aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt
     1741 ttggatctta ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat
     1801 gcttttaaaa aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat
     1861 tactacaata gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt
     1921 actaaaagtc aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt
     1981 aatcctaata aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg
     2041 gagcaatact atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac
     2101 gaaaaagaga ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat
     2161 atcatcgttc cagcaggatc tacatcttgg gggccaagaa tagatttact tttaaaaccc
     2221 gatgtttcag cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca
     2281 acttatggct atatgtcagg aactagtatg gcgactccaa tcgtggcagc ttctactgtt
     2341 ttgattagac cgaaattaaa ggaaatgctt gaaagacctg tattgaaaaa tcttaaggga
     2401 gatgacaaaa tagatcttac aagtcttaca aaaattgccc tacaaaatac tgcgcgacct
     2461 atgatggatg caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacaacag
     2521 ggagcaggcc taattaatgt ggccaatgct ttgagaaatg aagttgtagc aactttcaaa
     2581 aacacggatt ctaaaggttt ggtaaactca tatggttcca tttctcttaa agaaataaaa
     2641 ggtgataaaa aatactttac aatcaagctt cacaatacat caaacagacc tttgactttt
     2701 aaagtttcag catcagcgat aactacagat tctctaactg acagattaaa acttgatgaa
     2761 acatataaag atgaaaaatc tccatatggt aagcaaattg ttccagaaat tcacccagaa
     2821 aaagtcaaag gagcaaatat cacatttgag catgatactt tcactatagg cgcaaattct
     2881 agctttgatt tgaatgcggt tataaatgtt ggagaggcca aaaacaaaaa taaatttgta
     2941 gaatcattta ttcattttga gtcagtggaa gaaatggaag ctctaaactc caacgggaag
     3001 aaaataaact tccaaccttc tttgtcgatg cctctaatgg gatttgctgg gaattggaac
     3061 cacgaaccaa tccttgataa atgggcttgg gaagaagggt caagatcaaa aacactggga
     3121 ggttatgatg atgatggtaa accgaaaatt ccaggaacct taaataaggg aattggtgga
     3181 gaacatggta tagataaatt taatccagca ggagttatac aaaatagaaa agataaaaat
     3241 acaacatccc tggatcaaaa tccagaatta tttgctttca ataaccaagg gatcaacgct
     3301 ccatcatcaa gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct
     3361 caagatgctc aacttgaaag aggattaaca ccttctccac ttgtattaag aagtgcagaa
     3421 gaaggattga tttcaatagt aaatacaaat aaagagggag aaaatcaaag agacttaaaa
     3481 gtcatttcga gagaacactt tattagagga attttaaatt ctaaaagcaa tgatgcaaag
     3541 ggaatcaaat catctaaact aaaagtttgg ggtgacttga agtgggatgg actcatctat
     3601 aatcctagag gtagagaaga aaatgcacca gaaagtaagg ataatcaaga tcctgctact
     3661 aagataagag gtcaatttga accgattgcg gaaggtcaat atttctataa atttaaatat
     3721 agattaacta aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacacc
     3781 gcccctaaga ttgtttcggt tgatttttca aatcctgaaa aaattaagtt gattacaaag
     3841 gatacttatc ataaggtaaa agatcagtat aagaatgaaa cgctatttgc gagagatcaa
     3901 aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag tttggtatgc tggcgccgct
     3961 cttgttaatg aagatggaga ggttgaaaaa aatcttgaag taacttacgc aggtgagggt
     4021 caaggaagaa atagaaaact tgataaagac ggaaatacca tttatgaaat taaaggtgcg
     4081 ggagatttaa ggggaaaaat cattgaagtc attgcattag atggttctag caatttcaca
     4141 aagattcata gaattaaatt tgctaatcat gctgatgaaa aggggatgat ttcttattac
     4201 ctagtagatc ctgacaaaga tgcttctaaa tatgaaaaac ttggtgaaat ttctgaagat
     4261 aaactcaaaa atgcaaagag cccagaggaa aataccaata ataatcaagc taaggatgaa
     4321 gattcaaaac cagatgaaaa aagttcagtt gagggagaag ctagccttga aataaataaa
     4381 actatttcaa caattagaga gtttgaaaat aaagacctaa agaaactcat taaaaagaaa
     4441 tttagagaag ttgatgattt tacaagtgaa actggtaaga gaatagagga atacgattat
     4501 aaatacgatg ataagggaaa tattattgct tatgacgatg gtagtgcctt acaatatgaa
     4561 actgaaaaac ttgacgaaat aaaatcaaaa atttatggtg ttctaagccc atctaaagat
     4621 ggacactttg aaattcttgg aaagataagc aatgtttcta aaaatgccaa ggtatattat
     4681 ggaaatagct ataaatcgat agaaatcaaa gcgactaagt atgattcaca ttcaaaaacg
     4741 atgatatttg atttatacgc taatattaat gatattgtag atggattagc ttttgctgga
     4801 gatatgagat tatttgttaa agatgacaat caaataaaag ctgaaactaa gattagaatg
     4861 cctgaaaaaa ataaggaaac taaagcagaa tatccctatg tatcaagtta tgggaatgta
     4921 atcgaattag gagaaggaga tctttcaaag aacaaaccag acaatttaac taaaatggaa
     4981 tctggtaaaa tctattctga ttcagaaaaa caacaatatc tgttaaagga taacatcatt
     5041 ctaagaaaag gctatgcact aaaagtgact acctataatc ctggaaaaac ggatatgtta
     5101 gaaggaaatg gagtctatag caaggaagat atagcaaaaa tacaaaaggc caatcctaat
     5161 ctaagagtcc tttcagaaac aacaatttat gctgatagta gaaatgttga agatggaaga
     5221 agtacccaag ctgtattaat gtcggctttg gacggcttta acattataag gtatcaagtg
     5281 tttacattta aaatgaacga taaaggggaa gctatcgata aagacggaaa tcttgtgaca
     5341 gattcttcta aacttgtatt atttggtaag gatgataaag aatacactgg agaggataag
     5401 tccaatgtag aagctataaa agaagatggc tccatgttat ttattgatac caaaccagta
     5461 aacctttcaa tggataagaa ctactttaat ccatctaaat ctaataaaat ttatgtacga
     5521 aatccagaat tttatttaag aggtaagatt tctgataagg gtggttttaa ctgggaattg
     5581 agagttaatg aatcggttgt agataattat ttaatctacg gagatttaca cattgataac
     5641 actagagatt ttaatattaa gctgaatgtt aaagacggtg acatcatgga ctggggaatg
     5701 aaagactata aagcaaacgg atttccagat aaggtaacag atatggatgg aaatgtttat
     5761 cttcaaactg gctatagcga tttgaatgct aaagcagttg gagtccacta tcagttttta
     5821 tatgataatg ttaaacccga agtaaacatt gatcctaagg gaaatactag tatcgaatat
     5881 gctgatggaa aatctgtagt ctttaacatc aatgataaaa gaaataatgg attcgatggt
     5941 gagattcaag aacaacatat ttatgtaaat ggaaaagaat atacatcatt tgatgatatt
     6001 aaacaaataa cagacaagac actaaacatt aagattgttg taaaagattt tgcaagaaat
     6061 acaaccgtaa aagaattcat tttaaataaa gatacgggag aggtaagtga attaaaacct
     6121 catagggtaa ctgtgaccat tcaaaatgga aaagaaatga gttcaacgat agtgtcggaa
     6181 gaagatttta ttttacctgt ttataagggt gaattagaaa aaggatacca atttgatggt
     6241 tgggaaattt ctggtttcga aggtaaaaaa gacgctggct atgttattaa tctatcaaaa
     6301 gataccttta taaaacctgt attcaagaaa atagaggaga aaaaggagga agaaaataaa
     6361 cctacttttg atgtatcgaa aaagaaagat aacccacaag taaaccatag tcaattaaat
     6421 gaaagtcaca gaaaagagga tttacaaaga gaagatcatt cacaaaaatc tgattcaact
     6481 aaggatgtta cagctacagt tcttgataaa aacaatatca gtagtaaatc aactactaac
     6541 aatcctaata agttgccaaa aactggaaca gcaagcggag cccagacact attagctgcc
     6601 ggaataatgt ttatagtagg aatttttctt ggattgaaga aaaaaaatca agattaagac
     6661 aaaagctata gaaaaaaatg gtttatgtac tgagattaga tagtgaggtg atgacatagt
     6721 tttgtgaaaa cagccattta taactcaatt atttagttta cttcactatt gatactattt
     6781 ggagttatta atggacttag tttagataac taatgaattg attgaaaggg ttagtattga
     6841 caatattggt catattgatt agaaaataga gtctatcaaa atttaaaggc taatagaggt
     6901 gatgagacaa tttcggctct ttgtcaactg tagtgggttg aagtcagcta agctcgagaa
     6961 aggacaaatt ttgtcctttc ttttttgata ttcagagcga tgaaaatccg ttttttgaag
     7021 ttttcaaagt ttcgaaaacc aaaggcattg cgcttgataa gtttgatgag attattggtc
     7081 gcttccagtt tggcattaga atagtgtagt tgaagggcat tgacaatctt ctctttatct
     7141 ttgaggaagg ttttagagga tgaacctgat tcagattgtc ctcaatgagt ccgaaaaatt
     7201 tgtcaggctc cttattctga aagtgaaaaa gcaagagttg atagagatta tagtggtgtt
     7261 tcaagtcttc tgaatagctc aaaagtttat ctatagtaga ttgaaactag aatagtacac
     7321 ctctgcttct aaaacattgt tagaaatcga tttgactgtc ctgaatgatt tgtcctgtta
     7381 ttatttcatt ttactataaa tccacgttta cgaatctctt tccacacttg ttcaatgggg
     7441 ttcatctctg gtgtgtatgg aggaataaat gcaaaaccaa tattagtcgg aatctttaag
     7501 gtacttgatt tatgccatat agcattgtcc ataacgagta aaagataatc atctggataa
     7561 gcttgtgaaa gctcctattc ctaaagcccc tttataacct cttgcgagag agactattga
     7621 ctcagccctt acttcatgcg gatgaaactt cttatcgggt tctagagagt catagccatc
     7681 tgacctacta ttggaccttt ttgtctggga aagttgagaa tcaagcaatc acgctgtacc
     7741 atcatgatca gagtcggagt ggttcggtag tacaagaatt cctaggagat tattctggct
     7801 atgttcattg tgatatgttg cggcagtaac ttaggacttt agtcctctag ttctgcctat
     7861 gcgatagcag tccaaggttt aggagcaagg cgacgctaag cttggtaaac tgcgaactgc
     7921 tagaagctta tcgtcaactg gaagaagctg aacttgttgg atgttgggcg catgtgagaa
     7981 ggaaattttt tgaagcgacc cccaagcaag cagataaatc atccttagga gctaaaggtt
     8041 tagcttattg tgatcagtta ttttccttgg aaagagactg ggaggctttg ccagctgatg
     8101 aacgactaca gaaacgtcaa gaacatctcc agcccctaat ggaagacttc tttgcttggt
     8161 gccgccgtca gtcagtttta gcaggttcaa aactaggaag ggcaattgaa tacagcctca
     8221 agtatgaaga aacctttaag actattttga aagacggaca tctggtcctt tccaataatc
     8281 tagctgaacg cgccattaaa tcattggtta tgggacggag taaaagagtc cagtggactc
     8341 ttttagcctg agctcagttt aaaaaagcga gggtggttat tttctcaaag ttttgaagga
     8401 gctaaagcaa gagctattat tatgagcttg ttggaaacag ctaaacgtca tcaattatag
     8461 tgcgttgaat ctataacagt acgcatcgac tgctaaaaca tttctataaa tcaattttcc
     8521 tttcctaatc gatttgttca tatcttattt caatccatta taaatagcga gaaatatcta
     8581 tcctatcttc tagaatgtct tccaaacgag gaaactctcg taaacaaaga ggttttagag
     8641 gcctatttac catggactaa agttgtacaa gaaaagtgca aataagaaat ctccagatta
     8701 ggaactatcc gtgagttcac taatctggag atttttcaat agacttcgtt attgggcggt
     8761 tacgatatga tcactgactt cgtcagtctt atctacaacc tcaaaactgt gttttgagca
     8821 acctgcggct agcttcctag tttgctcttt gattttcatt gagtattaga acagaaaaaa
     8881 tacttggagt atttgtttgt gtgtttattt ttatataaca aactataaac aaaacaaaaa
     8941 tataaaaaaa gagacaaaaa agaacagaaa gcaattgaca acggtttcat atagtgttat
     9001 acttatggca taaagttaat ggaaagaagg gaaaaactta tggtattaga ttatttcttt
     9061 gacaaaaacc ttgtgttttg cttagaagcg gataatcaag aacaactctt tgatcaggtt
     9121 gcaactttat tggaagaacg agaaattgt
//
LOCUS       DAVBEM010000067         9077 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVBEM010000067 DAVBEM010000000
VERSION     DAVBEM010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9077
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.067"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(135..1103)
                     /locus_tag="VQ548_001915"
     CDS             complement(135..1103)
                     /locus_tag="VQ548_001915"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET2654712.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(1248..2063)
                     /locus_tag="VQ548_001916"
     CDS             complement(1248..2063)
                     /locus_tag="VQ548_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HET2654713.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKKVLILSLLGGMFLSGWLSSFTNTYIHDLLGVLFPD
                     SPFLNAFESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIG
                     YIRTDLPEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAHKEQKVGKKQGLI
                     FLGLALRTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(2088..2585)
                     /locus_tag="VQ548_001917"
     CDS             complement(2088..2585)
                     /locus_tag="VQ548_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HET2654714.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(2658..4019)
                     /gene="radA"
                     /locus_tag="VQ548_001918"
     CDS             complement(2658..4019)
                     /gene="radA"
                     /locus_tag="VQ548_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HET2654715.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MSVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(4033..4548)
                     /locus_tag="VQ548_001919"
     CDS             complement(4033..4548)
                     /locus_tag="VQ548_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2654716.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGFPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(4550..4993)
                     /locus_tag="VQ548_001920"
     CDS             complement(4550..4993)
                     /locus_tag="VQ548_001920"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HET2654717.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(5050..5147)
                     /gene="ffs"
                     /locus_tag="VQ548_001921"
     ncRNA           complement(5050..5147)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VQ548_001921"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5180..5647)
                     /locus_tag="VQ548_001922"
     CDS             complement(5180..5647)
                     /locus_tag="VQ548_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HET2654718.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(5848..7134)
                     /locus_tag="VQ548_001923"
     CDS             complement(5848..7134)
                     /locus_tag="VQ548_001923"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HET2654719.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGIGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGARNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(7365..7601)
                     /locus_tag="VQ548_001924"
     CDS             complement(7365..7601)
                     /locus_tag="VQ548_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HET2654720.1"
                     /translation="MLQKIYEQMTNFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            7867..8664
                     /locus_tag="VQ548_001925"
                     /pseudo
     CDS             7867..8664
                     /locus_tag="VQ548_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8699..>9077)
                     /locus_tag="VQ548_001926"
     CDS             complement(8699..>9077)
                     /locus_tag="VQ548_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET2654721.1"
                     /translation="RGKVSGRRYQRISLVAGLTNGELIAPMTYEEMVTSDFFEAWFQK
                     FLLPTLTTPSVIIMDNARFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWAYIKK
                     NLKKVLPSCNTFYEALFSCSCFN"
BASE COUNT         2907 a         2161 c         1459 g         2550 t
ORIGIN      
        1 tgatgacgta cagtcatatt tcttctcttt ttattatatc acagttttaa atctagcttt
       61 actagattca ccgctactat ctatttattc ggaaaaaaga cgaaaaaacc tgagaatcat
      121 ctcaggcttg gtcattaaat ttttttctca atatcgaaaa gtggagaaag tggtcgtttt
      181 tcatgaatac gtacgatagc atcccctagg agatgagcga ttgaaatctg ctcaatctta
      241 tcaatcaaac gctcttctgg cagatagatg gtatccaaaa caaccaattt cttaatagct
      301 gatttttgga tattgtccgt agcaggacca gaaagaactg ggtgcgtaca gcttgcatag
      361 acttcaacag caccagcttc cgcaagagca tctgccgcat gacaaatcgt tccagcggta
      421 tcaatcatat catcaatcaa gatacaagtc ttgccttcaa ccttaccgat gatgttcata
      481 acttcactag tattcatctt atcaacgcta cgacgtttat caataatagc gatagatgtt
      541 ttcaaaaatt ctgccaactt acgagcacga gtcacccctc catggtccgg gctgacaacc
      601 acatagtcag aaccaaccat accacgacgc tcaaaataat ctgcaatcag aggagcaccc
      661 atcaaatgat ccacaggaat atcaaagaat ccttgaattt gcgcagcatg caagtcgatg
      721 gtcaataaac gatccactcc agctacttca agcatatttg cgacaagttt tgaagtgatt
      781 ggctcacgcg ctctcgcctt tctatcctga cgtgcatacc catagtaagg catgacaaca
      841 ttgacagatt ctgcactcgc acgcttcaaa gcatctacca taatcaaaat ttcaagcaga
      901 ttgtcattta caggcgaact agttgattgt aggataaaga cgtgtttccc acggattgat
      961 tcttcaatgt tgacctgaat ctctccatct gaaaattggc gaacacttga tttccccaac
     1021 tctatcccaa tctcctgcgc cacacgttct gccaattctt tattagaaga aagggcaaac
     1081 agctttaaat cagaaaaaga catgatttcc tccggtatat atgtatcgct tgtgcttttc
     1141 acaagatttt ccatctacca ttgtagcgct ttttgcacta tttttcaatc aaaaataaaa
     1201 gaagggcacc atatttgtac ccttgcatca ttcttttgaa aaatattcta ggtcatcaac
     1261 tcattgtgtt tctcaacaaa gcaataagca tgataaaaac catagagagc aatagccgta
     1321 accactggaa tcgctaaagg caactctgtt tccaactcca caaaaggaga gttaaacaag
     1381 aagtgagttc tcaaggctaa acctagaaaa ataaggccct gtttcttgcc aaccttctgt
     1441 tctttatggg ctctgtaaag caagtaaaca cctactacag ctagacctga aaaagtccag
     1501 tgagaggcaa ttcctgagat gatacgctct aaaattcgcg aaatagtaaa gtcaaagccc
     1561 tctggcaaat ccgtacgaat ataaccaata tcctcaatca tttggaatcc caaaccggaa
     1621 gcaattccaa gtaaaaacaa agattttaat tttcgcacag gaatcaaagc caaaacaaaa
     1681 acaagtggca ataatttcaa gggttcttct accaaaggag ccacaatagc actttcaaag
     1741 gcatttaaaa atggactatc tgggaaaaga acccccagta aatcatggat ataagtatta
     1801 gtaaaactag acaaccagcc tgaaaggaac atccctccca ataaagacag aatcaaaacc
     1861 ttctttggca attcccattt tttcccaata cggaagagaa aataaagagc cggaatcatg
     1921 taaaagagag ctagaaagat agaaactccc attagtccat attccgcacc tgacctcgaa
     1981 ccgtccgtat agtagatggt ttcatactgt aaaccaatac atagcaataa aataaaaata
     2041 aataaaatac tgcttttctt catacacttt ctttctaaat gaagtattta taattctacg
     2101 actgtcatac ttcctgtatc aacattgtaa atggcaccag agataatgac atcgtctggt
     2161 attaggggag actcgataag cagttgcata tcctcgcgta cactctcttc tatatcttgg
     2221 aagggcaaga agtcctggtc tgacacatct acacctaatt cctcttttaa atactcctga
     2281 aaaggttcat tttcaaaggt ctgagcacca cagtctgtat ggtgcaatac cacaatctct
     2341 cttgtcccca tttgttgctg ggaaataact agcgaacgaa tcatgtcttc agtcactcga
     2401 ccacctgcat tccgcaagat atgagcatcc ccaagtgcca agcccagagc ttgcgcaacg
     2461 tgcagacgag agtccataca ggtcacaata gctactcttg ttttgggttt aagtggcaga
     2521 tttaactgcc catgtagggc aacataagcc tgattagctt gcataaactg ttcaaaatac
     2581 gacacgattc cctccttgaa aatttgatag tcaaatattt ctcctatctt atcattttta
     2641 agagaatttg tcacggatta tgcaaagacc tttttcaaaa cttcctgaat cgttgtcacg
     2701 ccaatgacct gaatttcctt aggcagagtg attcctgtca aggaattctt aggtacataa
     2761 atcttagtaa agcccagttt agcagcttcg ttgatgcgtt gctcaatacg attcacgcgc
     2821 cgaatctctc ctgtcaagcc cagttctccg acaaaacatt cctgaggatt agttggcttg
     2881 tctttgtagc tcgaagcaat agcaactgca acagccaagt caatggcagg ttcatccaat
     2941 ttaacaccac cagcagattt gagataggca tcctgatttt gcaagagaag ccctgcccgt
     3001 ttttccaaaa cagacataat caagctagca cggttaaaat caagtcctgt cgtagtacgc
     3061 ttggcatttc caaacatggt cggtgttacc aaagcctgaa cctccgccaa aatcggacgc
     3121 gtcccttcca tggttacaac gatggaggaa ccagtcgccc catccaaacg ctcttctagg
     3181 aaaacttgac tcggattgag tacctcaacc aagccgcccg actgcatctc aaaaatccca
     3241 atctcattag tggaaccaaa acgatttttg accgctctca aaatacgaaa ggtgtggtga
     3301 cgctcccctt caaagtaaag caccgtatcc accatatgct ccaacatacg aggcccagcc
     3361 aaggttcctt ctttggtcac atgacctacg ataaagatgg caatgttatt ggtcttggcc
     3421 aactgcatga gttcagcggt cacttcacgc acctgagaaa cagacccctg cacccctgaa
     3481 atctcaggag acatgatggt ctggatggaa tcaataatga gaaagtctgg ctggatacgc
     3541 tccacttctg cacgaacact ctgcatattg gtctctgcat agagataaaa ctcactatca
     3601 atatcaccta agcgctctgc acgtagttta atctgctggg cagactcctc cccactgaca
     3661 tagagaactg tccccacttg ggacaactgg gttgagactt gtaggagaag agttgatttc
     3721 ccaatcccag gatccccacc gatgaggacg agacttcctg gtaccactcc gcctccaagc
     3781 acacggttga attcctccat ctccgtcttg gttcgattga cattgatgga agtcacctca
     3841 gctagtttca tgggcttggt tttctcacct gtcaaggaca cacgcgcatt cttgacctcg
     3901 gcaacctcaa cctcttccac aaaagaagac caagacccac agttggggca acgtcccaga
     3961 tatttagggg aattataccc acaattttga catacaaatg tcgctttttt ctttgcgatg
     4021 acaaacctct ttctatatct ctaactcaca ctcaatcact tggcaaaaat caatcttctc
     4081 atttggcaca aactggcgca tgagcattcg atgagcaaca actaccacag tctgatgttc
     4141 tcgatactta gacatacatt ctagaaaccg agacttcatt tccgtagctg tctcatattg
     4201 aataggacta ttaggaagca actccccctt gttttctaaa aacagtcttc tagctgtttc
     4261 aaagttttct attcctgttt tatagacctg ccattcatgt aataaaggct ctactcttaa
     4321 aggaaaaccc gtagcacata ccacatacga agccgtttct aaagctcttg tgactgcaga
     4381 agatacgatt atttcagctg acgagagtaa aggatttttg ctcaatttct ggacttgctg
     4441 ccgtcccatc tcagacaagg gtgccaaatc tatcccaaat cctatataag aacgctcctc
     4501 taactcacgg taatctggct ccccatgacg tacaaagata atcttcattc tagtgccctg
     4561 tcgatccaaa tccaccagtt cgaacgccat cagccgcatc tccatctgca attaagaaag
     4621 tagcaaaaac agcctggaca atacgctccc caacttcaag aacaacctct tggtctgtga
     4681 tattcttcat ctgcgcaaaa atatgccctt catttccagg atttccataa taatccccat
     4741 caatgactcc aactgagtta attaaaacca agcccttctt acgaggattt gaagaacgat
     4801 catagaggta gagaacctca gtcggctgca tataagcctt aacccctgtc ggaaccaaga
     4861 caatctctcc tggcgcaaca actgtacgca cagcaacctt taagtcgtaa ccagccgcat
     4921 gcgctgtctc acgcttgggc aataaatttt catctgtaaa actcgaaacc aattcaaaac
     4981 cacgaatttt cataattttc tcttttctat tatcatttat tctagattat tctatcttat
     5041 ttattcggaa aaagcacgaa aaaaagagca cacaattcaa atcgcttagg gctgctggat
     5101 tcctcccctg acccgcttca cgcagaactg ttgctccact atttattata tcacattcct
     5161 attcatttta aaagcaaaat tattttttcc gtctatttct aaaaaaatcc tgcatgatag
     5221 ctgcgcattc atcttccaaa attcctattt caacctccac acgatgatta agacgctcat
     5281 ctgtcaagat atcgtacaaa cttccagcag cgccaaattt ctggttttta gccccataga
     5341 ccacatttgg aatgcgggca agcccaatcg ccccactaca catgacacaa ggttcaatgg
     5401 tcacaaaaag tgtgcaatcc agcaagcgcc agctctcctc actcaagttc gcatcctcta
     5461 tagccataat ttccgcatgc ataaccgctc gctgtaattc ctcacgcgca ttatgcccac
     5521 gaccaatgat ttccccatct ttgacaatca cacaaccaat tggaatttca tcgtgttcaa
     5581 gagcaatctc agcctctctc aaagcctccc tcataaagac ttctttttct tcaagcgtat
     5641 aatacatctc ttttctcttt tcctacttat cgattttatt attatatcat gaatcccaac
     5701 acaaaaaaag ccaccgaatg cggtgactct atagggagat tattatgaaa aagaaaagtt
     5761 taggatattt gttacaacaa gttaggaggt cttcttgtaa ctgtctatag tatacccgac
     5821 ctatcttaaa caaatcttaa aaatctctta ggaccaaaca ctttctaaaa tatttgtttg
     5881 ttcacgacca ggacctactg agaaagtaga aatacgaacg ccaaccaatt cactcacacg
     5941 acgaacatag ttacgcgcat tctcaggaag atcttccaaa ttgcgagctc cggtaatatc
     6001 ttctgaccaa cctggcaact cttcatagat aggcttgcaa cgtttcaatt gctcaagact
     6061 agctggatag tagtcaatac gttgaccgtc aagatcatag gccacacaaa ttttcacagt
     6121 atccaagccg ctcaaaacat caatagagtt caaagaaagg ttagtaatac cagaaacacg
     6181 acggctatga cgcatcacaa ctgagtcaaa ccaacctaca cgacgtggac gaccagttgt
     6241 tgtaccatat tcatgaccca cttcacggat acgttctccc acttcatcaa acaactcagt
     6301 tgggaaagga ccatctccta cacgactcgt ataagcttta catacaccta caaccttgtc
     6361 aatcttgctt ggaccgatac cagaaccaat tgtcacacca ccagctacag ggtttgatga
     6421 cgtaacaaat ggataagtac cttgatcgat atctagcata acaccttgtg caccttcaaa
     6481 aagcacacgt ttgccattat caagcgcatc attcaagata acagatgtat ctatcacgta
     6541 tttcttgatt tgttgaccat attcgtaata ttcttcaaaa atatcatcga aaacaatcgc
     6601 tttactgtca tacaattttt caaaaagacg attcttttca gcaaggttac gttctaaacg
     6661 ctcacggaaa atatctttat ctaaaagatc tgcaatacga attccaacac gagcagcctt
     6721 gtccatataa gctggaccaa ttcccttaat tgtcgtacca atcttattgt cgcccttagc
     6781 ttcttcttgc aagcgatcca actcgatatg ataaggcaaa ataacatgcg cacgatcaga
     6841 aatacgcaag ttatcagttg ttacaccttc ctcatgaaga tagctcaact cttttacaag
     6901 agatttagga tttacaacca taccattccc aatgacagat attttttcag ggaagaaaat
     6961 cccagatgga atcaagtgca acttaaattt cttaccgtca atcacaatcg tgtgaccagc
     7021 attatcacca ccttggtaac gtgcaattac ttctgcattc gctgaaagga agtctgtaat
     7081 cttcccttta ccttcatcac cccattgggt acctacaaca acaactgaag tcataatttt
     7141 gtctgagccc tcaggctctt cctttctcac atacatggca ggactctcac ctgcaattat
     7201 atcttacaat ttattataat aaaaaatcgc ctttttatca agaagaaaca atagaaagat
     7261 ttgctatttc caactattaa aaaatgattt agaaaaatta ctagctattt actattatct
     7321 ttccataaaa gagtaaatta gttcggaaat ttactaaaat tacctcaaca agaaataaaa
     7381 ccccgattca ttaccaattt ttcaagatac aaacgataag caacacgata atggtaaacg
     7441 ataaaatccc tacgacaacc aatgccatat ctcactaaat aataaattaa aaatttaaaa
     7501 tgaacatgtt cccagtcaaa attatcacca aatgtaggac catactcttc ttcaatacta
     7561 tcatagaaat tagtcatctg ctcataaatt ttttgtaaca taatcaaata ctccttttct
     7621 tttttataaa cttattctaa caaaaaattt tacacattca ctatcaattc ctgaattgtt
     7681 aaaataccag cctcaacaag ataaaaatag gaaaagttga caaaatagaa acaaatttgc
     7741 tacctaaatt tcaaacgatt aaagttctaa aaagaccgcc ttaaaacttt tgggtaaatc
     7801 ctattagaac tataatattt atatatatgt attatggttc tgattttcta gtataaaaaa
     7861 attcaaacta gaattcttct tagaaaaggc cgttttaagt gctatcattg ctcaaaaatg
     7921 gaggtcgctg agacttctat cgtcaagaag aatcatcaaa ttccttgtat catcaaccaa
     7981 aagattgctc agaagttaat tgaaaagact tctatgaccg acattgatca tcagttgtct
     8041 atttcaactt caactgtcat tcgcaagatc aataattttc actttgagca tgatttttcg
     8101 cgtcttcctg agattatgtc ctaggacgtt gaaacagtcc ggggagtgac tgtttcaatc
     8161 gggagatgga gatgagcttt attgctcagg actttgataa actcaatatc ataactgttc
     8221 ttgagagcag aacacaagcc atcatccgaa atcccatgaa tacaaggcta tcaagcgcta
     8281 ctggaagctc attcaacaag atagtcagaa actgagtgat aaacgatttt atcgccctac
     8341 ttttcgtatg cacttgacta ataaagaaat tctagataaa cttttgagct attccgaaga
     8401 cttgaaacac cactataatc tctatcagct cttgcttttc cacctctgtt tcagactttg
     8461 tttaaaacct tcctcaaaga taaagagaaa atcgtcaacg cccttcaatt accttattcc
     8521 aacgccaaac tggaagccac caataatctc atcaaactta tcaagcacaa tgcctttggt
     8581 tttaggaact ttgaaaactt caaaaaagaa aggacgaaat ttgtcctttc tagatcttcg
     8641 ctttcttcaa cccactacag ttgacaaaga accgaaaaat gtctcgcctc taatatagtc
     8701 aattgaaaca agaacaagag aaaagagcct cgtaaaaggt attgcaactt ggtaatacct
     8761 ttttgaggtt ctttttgata taagcccatg ttttctcaat aggattgtac tcaggtgagt
     8821 agggaggaag aggtaaaagt ttatgcccaa actcctcgca taaaagttct aacttaccca
     8881 ttctatggaa tcttgcatta tccataataa taaccgatgg tgtggttaat gttggtaaga
     8941 gaaacttctg aaaccaagct tcaaaaaagt cgctcgtcac catctcttcg taagtcattg
     9001 gagcgattaa ctcaccattt gttagacctg caaccaaaga aatcctctga tatcttcttc
     9061 cagatacttt acctctt
//
LOCUS       DAVBEM010000068         8676 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVBEM010000068 DAVBEM010000000
VERSION     DAVBEM010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8676
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.068"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            264..1322
                     /locus_tag="VQ548_001927"
     CDS             264..1322
                     /locus_tag="VQ548_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654722.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTVWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALGDLSKQYLNRNISELQDGSFDGGIQDAVASKQIVVINEFIACLNSRCMPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            1637..2611
                     /locus_tag="VQ548_001928"
     CDS             1637..2611
                     /locus_tag="VQ548_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654723.1"
                     /translation="MKNKRYFFDTILMILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSTK"
     gene            2991..3365
                     /locus_tag="VQ548_001929"
     CDS             2991..3365
                     /locus_tag="VQ548_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HET2654724.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            3573..4475
                     /locus_tag="VQ548_001930"
     CDS             3573..4475
                     /locus_tag="VQ548_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654725.1"
                     /translation="MIRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEGLIKIFPFIFIRRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESNLHKILMDKIQKSELSYSDLMSLLLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            4531..4770
                     /locus_tag="VQ548_001931"
     CDS             4531..4770
                     /locus_tag="VQ548_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET2654726.1"
                     /translation="MELVLPNNYVVIDEEVMMYLDGGAYLSKRACQGICAAAGVLATA
                     AGKIAYCIGYGVLNRGCDINENPYPWDGFISATVR"
     gene            4767..5495
                     /locus_tag="VQ548_001932"
     CDS             4767..5495
                     /locus_tag="VQ548_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654727.1"
                     /translation="MSNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLVINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IRKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGKVDNHVLTLI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEYELFKNSK"
     gene            6630..6869
                     /locus_tag="VQ548_001933"
     CDS             6630..6869
                     /locus_tag="VQ548_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654728.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQDGVFILEDFRNILCTMM"
     gene            7419..>8676
                     /locus_tag="VQ548_001934"
     CDS             7419..>8676
                     /locus_tag="VQ548_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HET2654729.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPVASQSKAEK
                     DYDAAVKKYEAAKKEYEDGKAAQKKYEDDQKKTEEKAEEERKASEEEQAANLKYQQEL
                     VKYIRENDPTKKAEAKKAMDEAEKEYKKKQTEFAEVRAKVIPSAEELKKTRQKAEEAK
                     AKEAELTKKVEEAEKKVTEAKQKVDAEHAEEVAPQAKIAELEHEVQKLEKALKEIDES
                     DSEDYVKEGLRAPLQFELDVKQAKLSKLEELSDKIDELDAEIAKLEKDVEDFKNSDGE
                     QAGQYLAAAEEDLVAKKAELEKTEADLKKAVNEPEKPAEETPAPAPKPEQPAEQPKPA
                     PAPQPEKPAEEPENPAPAPQPEKSADQQAEEDYARRSEEEYNRLTQQQPPKAEKPAPA
                     PQPGWKQENGMWYFYNTDGSMATGWLQ"
BASE COUNT         3004 a         1177 c         1582 g         2913 t
ORIGIN      
        1 taaatctaat aaattctatt attatagctc ttggtatgat attggcatta attttggtat
       61 tatcaagagt gtatagaaaa tatttttata gagacgatga tgactaaagt ttttatcaat
      121 aatttgggct ccttgtcaac tgtagtggat tgaagaaaag ctaacgtctg gggaagggtt
      181 taaagctttg ctttatcaaa tattgactta cagagttgct ctattgtatt gatgtattct
      241 tagtaaataa tatggtgttt tgaatgaaag atgatcagaa atatttatta gcgggacttt
      301 attcgcttct agttgcaata ttttattttc cattgattga gtccaagggg atttttgtaa
      361 gtatattgat ggcggtttta cttttatatt taatatactt cattgcaaca gtcattcata
      421 ttgtgataat taagtttata agaaaaaaat cttttaagta tttggttcta tatccattta
      481 cttatgatgg gagctggaga tttcaaccta taaacttact ctactttcca gaaatggtga
      541 gagatgtcat tccgattaat ttagttcaag aatattgcca aggacaacct tacggactgt
      601 taaaaaagat gctgaaaaga attcgattgt cacgagagat agctttactc ctggctacca
      661 ttatcgtcta tttttttacg catagaattc tacctctttc agtatttacg ttcatatttt
      721 cttacatatt gctatttgca caatcttatt tgggtggtaa taccgtttgg attggaaata
      781 gaagattaat aatagatgat gaatttgaaa aaatcttgct ttcaaaaagt tatataaaag
      841 aaatatcatc tgcacgatac tcggaatact tgacatgtga atacaaaaac cttacaccaa
      901 tcatattgtt agctattttt gaaaatttgc ttgactccta cttgcttcag aatcagagtg
      961 aggttgactt agatattttt tataaagttt tacctttgct ttataaagaa aaatatacta
     1021 tgggattcaa ttactttgta agtttaaatt atttactata taaggttgga tttttgggaa
     1081 tcatttacga taatgaagca ttaggagatt tgtcaaaaca atatttaaac agaaatattt
     1141 cggaattaca agatggttct ttcgatggcg gtatacaaga tgctgttgcc tctaaacaaa
     1201 tagtagttat aaatgaattt atagcttgtt taaattccag atgcatgcca tcccaatatg
     1261 atagattttt ttataaagat agaccttata ttttttccag aaagagtcct attaaggggt
     1321 gaaaatttgt tacatttgga ttaacaagtg tcctagggat tagaaataac tctagtatag
     1381 ctagatattt ttgagtaact agaaatatca ttaggctacc catatgattg ccagaaaaga
     1441 tggctgatga atcttattta tactgttgca gtaggcattg tctaggataa ataagctatc
     1501 ttgatggggg aaattggaat aattttagta gaaacattaa aggattatgg acaagtagcg
     1561 caggattagg tgatgcaatg tgctaagttg gcttggtgtt agcagtagta ttatttaaca
     1621 atggaaagta gactaaatga aaaataagcg ttattttttt gacacaattt taatgatttt
     1681 actgcttata agcacgatat tttgtgtcag cccagtattt ataaaattgg acatcttagg
     1741 aaccccctct catgccatct taacctttgt attggcgata ccgttattct atattttgtc
     1801 tcaatgctta catactttgc tattactagt ttcctcaatc ttttgtaaat taagaccaat
     1861 ttatttttat tttatatttg tgatcattat aggagctagg aaatactatc gaattctctt
     1921 tcaccaacta atgggattta gtccaggaat agcagtgttt tataaggaga gtcaaacaac
     1981 taagaatctg tttaaatttt actacttctt gtactttaca acactaattt catactattt
     2041 tttctttact tttgtgtatg acaaaccgtt gcttttgcct cttattccat tttctattat
     2101 catagcatta gtacaaaaac tttatagaat tgagaatcaa caattatttc tgttaaaatc
     2161 aaaggtacta acaatactgg aatctaagaa gaattgtgag tttaatcttc aggattatca
     2221 tgaaatttgg aaattgcaat caaaatctga gttgccatgc gtggctttat cttatatcag
     2281 tttgatcaag ccatatcttt cagagagcgt gcgtgaacaa attgatttat tagaagttaa
     2341 gcgatttaaa aaaataaatc atccaatatc actttatggt atgttggatg ttataaaatt
     2401 aaatctatat ttacggcatt ataatgaaaa aaataaatat gaatcaatgt taaagaaaat
     2461 tttagaggta agaccagact ttgttttaat cgagcagaat attgatgata gtttaaatag
     2521 ctcgcaacca ttatctttat ctttagccat ttcagaaatc caacttttgc ttgaagtgta
     2581 tatggggatc aaacatgttt caaccaagtg ataaaaccag aataatattt gccattatag
     2641 gggcaagttg catattagtc agtatgtatc ttattccact tattaaaact gagaataaat
     2701 tttgggaaat acttttattt atattaggtg tattgctaat tggaattgcg ttactaagtc
     2761 aaaaaaaata aattttgaaa tagtattagt gagttcgcaa tcatttattg ctagtggttt
     2821 agaactgtta agtttcaaac aataattgat tttaaacctt aggtaaccta taaaaacaaa
     2881 taaggtagag aaaggatatc ttatctaggt agctaagtga taaaaacaca gtcgtctatc
     2941 acttgttagg aaactatcct aactatgctt aataaaaaag gagaaaataa atggaactcg
     3001 tattaccaaa taattatgtt gttcttgagc aagaagagat gatgtatctt gatgggggat
     3061 tttctattcc gagatggcct gttgcaacag ccattaatat agcttttaat ggtgttttag
     3121 gtggaggagc aatcagtcta gttagaaatt atattcgtaa ttatggtttg cggcgagtta
     3181 caagcgcaat tgctggagca gctgcaagat atgttggggt acgagttgca aatagagtgg
     3241 caggatttgc actgtctgct attaatggat ttgcagcttg gatgtcaatt ggcgatgcta
     3301 ttacaacaat ctgggccaac aatgatgtaa ataggagaga cccaaattta aacgccttgt
     3361 ggtaactaga tatgggtatt aaaatggaaa aaatttttgt tattattttt tttgtatgtc
     3421 tatttatatc atccataact tttttagcct atgattttgt tagcgaagaa ataaaaaagt
     3481 tgattatttg gattaatgtc gtttttttga ttttaatcat agcaatgatg atttatccaa
     3541 aattaagaaa atgataagga cactgtaaaa ttatgatacg taaactaatt gttttcttac
     3601 taatgctccc tctttttgtc ttgtggctag agttgcatgt cctagtgaat aacttactat
     3661 tgaatctaga atctcccctt gattttgtga ttagtatgag tcttgctttc tgtagtttga
     3721 ttttatcaaa aatagtttta gacatactat acgcattgaa agatttatac aagaaagaag
     3781 gtcttattaa gatttttccc tttattttta taagaaggaa aaaagtgaat gtgagattct
     3841 cgccctattt ttcattccat cgtaaaagtt tgtcgcctga tgatttaaga tctaggatta
     3901 tatggagttt tattcttgaa attgctatta tcctagtatt tattttaaaa attccttttg
     3961 caatcatcat gcttactaca atatttttct ggactataat ggatatcaat catctcgttt
     4021 ttaataagac ggaatttctt tttaatcaaa acaaatggca aaaagaagat tcatttgaaa
     4081 gtaatttgca taagatattg atggacaaaa tacaaaaatc agaattaagc tattctgact
     4141 taatgtccct tcttctctat gatgcgatga accaatccac ctttttaacg gatagtgaac
     4201 tttttgagga tattttgaaa aaaatcgaag attctcataa cacccttctg tgtacaggtc
     4261 ttgtcgagtt actgctgtat gagatttcta ttagtaacaa taacaactgg caagaaaagg
     4321 ttgataaaat tagaatacag ctcatcagaa tcaatcaatt agattttttc tattatacaa
     4381 gttggttaag gcaaaatttt gatttctgta tgaatagaga gtatcataaa atgaaatctc
     4441 ggaaattatt actgagtaat aaaaagatag tttaagttcg tcctatttgt aaaacaaatg
     4501 aaacaatttc aactaaggag gagaaaacaa atggaacttg tattaccaaa taattatgtt
     4561 gtgattgatg aagaagtaat gatgtatctt gatgggggag cttatttaag caagcgtgct
     4621 tgtcaaggaa tttgcgcagc agcaggtgta ttggctacag cagcagggaa aatagcttac
     4681 tgtattggat atggtgttct taatagaggt tgtgatatta acgagaaccc ttatccttgg
     4741 gatggattca tatctgcaac agtaagatga gtaatgtaga taagattcga aaaatacaca
     4801 tcatcgtgtg ttgggtgtat atatttttat cattcagggc gattataaat gatacggagt
     4861 attttttgct tattttttta gcttttatct actcaatagt atcactacct ctatattctg
     4921 tgaaaaataa aatagtatct atctgtctag ttataaattc gattctgtta atgagtttcc
     4981 ccattttaat caataagttt ttcccagaaa gttttttgac ttataccgta ttaataagtg
     5041 tttttatcct agagttagca atctttcatt taattaggaa agattttgat attaaattga
     5101 ctaacgaata taagaaaatt agtcagttta gaagcaaggt gtctcaatct ccttggataa
     5161 aatatttaga gatttctagt tttatattaa ctatatttcc atctattctt tatggtaaag
     5221 ttgataatca tgtactgact cttatctttt tgataaaaat ttgtgtagat actacgataa
     5281 aatttttatt catcagatta tttgacacaa gtactttaat gaagaggaga atattttttc
     5341 ttttcgcatt ggatgttata gcttacttat ttttaggata tcttttagtg attcaaaaag
     5401 caggctattt gttttcggtt ttacttcttt tttctaattt ttcagttcca tttatcaaag
     5461 aaaaggaata cgaattattt aaaaatagca agtaatagaa atatggatta aatcttagaa
     5521 cggcttaaaa tcagatatga taaagggaaa tagtcttatc taggtaacta agtgctacaa
     5581 acacaatcga ggatcacttg ttaggattac attttaatca tgcttaataa gaatggagaa
     5641 ttcctatggg gattgtatta ctctgaagtt tcgaatacct tagttctcgt gattttgagc
     5701 tattctagct ttagaatcct tcagaacgta aaattttaag cagtcaaaga cttagaatag
     5761 cctgaaaaca tttattttat agcaattcta ggcttagaat tgctcatata tatgtatttg
     5821 agctgctcga tagttaggac agctctattc tgagaaatct gagctatcaa tgcttcagaa
     5881 tagtatttcg ccaatggttt ttattgaaga ggtgattgtg ttatgatagt ctaaaataaa
     5941 attgatttaa tagagtaaat ggagaatcgt tacatgaaac atttttttgc aggaattggt
     6001 gagataaaac ttgttggcta cttattgtat atatgtgtag gactagcccc tctttttcat
     6061 atatatgtca taggttcgga actgagtttt gtgaaaatag tgttatctat tttgggagtt
     6121 atatttgtaa gtatgttaac tattgctcga atttatcgga cttttctata aagaatagtt
     6181 tggacttaaa ctgtatctaa aaacagaggt tggtcgatta tcagcctctt tcttgtcgtt
     6241 gaaaagagtg agatatattg acttttgaaa aaaagatgtc ataattgagt tgggataaac
     6301 ctaaaagtaa tatagtagat tgaatctgga atagtccgtt atgactgtta aaatatttct
     6361 agaaattaat ttgactttcc taatcgattt gttcacatct tgtttcaatc tactatactt
     6421 tctcgttaaa ccgttcggca attcatggtg acatggacac atagtagtaa gcacactatg
     6481 tggcttggca gagctaaaaa ctgttccctt gcgataagcc taataagcac aacataggga
     6541 gttagagaag ccgactctaa tcaaccactt tgggcaatag tgagaactgc cccgtgcttt
     6601 tttattttga gaaaatatgg agtttgtcgt tgaaattact tgattgtatt ttggactatc
     6661 aagaaagatt caatggaaaa acatgtcaag tatcaacgaa ttataagtat ttagagattt
     6721 tcaaagtgaa tttttgtttg actgatttac atcatttatt tgacttatac aaaatcacac
     6781 gagattatgc tagtcaaaca aaacctgcta ttcaagatgg tgtttttatt ttagaagatt
     6841 ttagaaatat cctatgtaca atgatgtaat cgaaaggata tctttatgtg agtttatcgg
     6901 cgatatcttc tatatctaag ctagcaagtt gttgcatcgt agctaaggat ttatctaaaa
     6961 atactatgaa attggacgtc atattttttg aggataaaaa taaaagatcc gcagttttag
     7021 gtttacgaag agacaaaagc ggagtattta aaccagttac tctacatttt acaagcgcta
     7081 agaaatatgc taaagttcgt aaaacagatg tgaaagaaat gaaatggcta taaagattgt
     7141 ccgcaggctt aagcttgcgt tttttgttgt ttaacgaaat taaaaaacaa gctctctcat
     7201 cggaaatgtt tttataggaa tgaaggaaga tgatgctatg tttaaaaaga gaatcgaaaa
     7261 gggcaaaagt agtgtcttta tctttttgga gtagaagctt atgatataga aatttgtaat
     7321 aaaaatgtaa tataaaacat ttgacaaata tttacggggg gagtatactt aatataagta
     7381 tagtctaaaa atgactatca gaaaagaggt aaatttagat gaataagaaa aaaatgattt
     7441 taacaagtct agccagcgtc gctatcttag gggctggttt tgttacgtct caacctactt
     7501 ttgtaagagc agaagaagct cccgtagcta gtcagtctaa agctgagaaa gactatgatg
     7561 cagcagtgaa aaaatatgaa gctgctaaga aggaatatga ggacggaaaa gctgctcaga
     7621 aaaagtatga agatgatcag aagaaaactg aggagaaagc ggaagaagaa agaaaagctt
     7681 ctgaagaaga acaagctgca aatctgaaat atcaacaaga gttggttaaa tatatacgtg
     7741 aaaatgatcc aacaaaaaaa gctgaagcta agaaagcaat ggatgaggct gagaaagagt
     7801 ataagaaaaa acaaacggaa tttgctgaag ttcgtgcaaa ggtaattcct agcgcggaag
     7861 aattaaaaaa gactagacaa aaagcagaag aggctaaagc aaaagaagca gaacttacta
     7921 aaaaagtaga agaagctgag aaaaaagtta ctgaagccaa acaaaaagtg gatgcagaac
     7981 atgctgaaga agtcgctcct caagctaaaa tcgctgaatt ggaacatgaa gttcagaaac
     8041 tagaaaaagc tctcaaagag attgatgagt ctgattcaga agattatgtt aaagaaggtc
     8101 tccgtgctcc tcttcaattt gaattggatg ttaagcaagc taaactatca aaacttgaag
     8161 agttgagtga taagattgat gagttagacg ctgaaattgc aaaacttgaa aaagatgtag
     8221 aagatttcaa aaactcagac ggtgagcaag ctggacaata ccttgctgca gctgaagaag
     8281 acttagttgc taaaaaagct gaattagaaa aaactgaagc tgaccttaag aaagcagtta
     8341 atgagccaga aaaaccagct gaagaaactc cagctccagc accaaaacca gagcaaccag
     8401 ctgaacaacc aaaaccagcg ccggctcctc aaccagaaaa accagctgaa gagcctgaga
     8461 atccagctcc agcaccacaa ccagagaagt cagcagatca acaagctgaa gaagactatg
     8521 ctcgtagatc agaagaagaa tataatcgct tgacccaaca gcaaccgcca aaagcagaaa
     8581 aaccagctcc tgcaccacaa ccaggttgga aacaagaaaa cggtatgtgg tacttctaca
     8641 atactgatgg ttcaatggct acaggttggc tacaaa
//
LOCUS       DAVBEM010000069         8484 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVBEM010000069 DAVBEM010000000
VERSION     DAVBEM010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8484
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.069"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            <1..1039
                     /locus_tag="VQ548_001935"
     CDS             <1..1039
                     /locus_tag="VQ548_001935"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. Subunit I is part of the
                     membrane proton channel; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HET2654730.1"
                     /translation="IKVMDERFGHSIYIYESETLSDNQDEIPIKLTNHSLIEPFELLT
                     EMYALPKYYEKDPTPVLAPFYFTFFGMMVADLGYGLLLFLGTMLALKIFHLPSETKRF
                     LKFFNILGVAVAIWGGIYGSFFGYELPFHLISTTSDVMIILVVSVVFGFITVFAGLLA
                     SGLQKVRMKKYAEAYNSGFVWCVILLGLLFIAVGMLMPDMRLLFVLGKWVSIFNAVGI
                     LVVSIIQAKSLSGIGAGLFNLYNISSYIGDLVSFTRLMALGLSGASIASAFNLIVGLF
                     PGTLAKLTIGLVLFILLHAINIFLSLLSGYVHGARLIFVEFFGKFYEGGGKPFQPLKA
                     SEKYIKVITKN"
     gene            1055..1531
                     /locus_tag="VQ548_001936"
     CDS             1055..1531
                     /locus_tag="VQ548_001936"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HET2654731.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            1565..2146
                     /locus_tag="VQ548_001937"
     CDS             1565..2146
                     /locus_tag="VQ548_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654732.1"
                     /translation="MSNLENLRESVIEQAHEKGRMKLLDSKKKIDDEFEMQKSVIVKK
                     KEVEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALIEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNHLFSEQPISNESGLLI
                     SIGKIDDNYLYKTLIGSISKEESSSIANQIFIN"
     gene            2211..3218
                     /locus_tag="VQ548_001938"
     CDS             2211..3218
                     /locus_tag="VQ548_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HET2654733.1"
                     /translation="MDTNLFSKINTTISVKENDFITEDKFQKIIQSKDTETMAFILEA
                     TPYHLSIDVLENPSQTETSLMTKLVNDYRWAYAESPSNKIVTLFALRYVYHNIKVLLK
                     SKAAIKKDFSKLLIPIGIFDIESLKHLVSSLHSDTLPDFMVHEVESIWNEYETFNNIR
                     VLDVGADLAYFKHLKLLSNELDEVLSQVIVAMIDFYNIITVKRGLSQNKSHGDILQLL
                     SDEGSISAKEFIYIVENQEIFVWFNKINPSLDSIFSTYELKMQDATISSSELEFLCDL
                     LLYKILDQGRYNVDGPLVLARYLLGCEFEVKNLRMIISALQNTIPFGSIKERIRPHYG
                     S"
     gene            3208..3528
                     /locus_tag="VQ548_001939"
     CDS             3208..3528
                     /locus_tag="VQ548_001939"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HET2654734.1"
                     /translation="MEANKYKIGIIGSRDIILPFSMIGFDIFPAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            3591..5366
                     /locus_tag="VQ548_001940"
     CDS             3591..5366
                     /locus_tag="VQ548_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HET2654735.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTIAIGQKVSTGDILGTVKETEVVNHKIMVPYGVSGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     TFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFSNVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQVLGIPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGIYIDGKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSDNERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIMEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIHLILETGGL"
     gene            5367..6752
                     /locus_tag="VQ548_001941"
     CDS             5367..6752
                     /locus_tag="VQ548_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HET2654736.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLSSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVRFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            6775..7386
                     /locus_tag="VQ548_001942"
     CDS             6775..7386
                     /locus_tag="VQ548_001942"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HET2654737.1"
                     /translation="MVRLNVKPTRMELNNLKERLKTAERGHKLLKDKRDELMRRFISL
                     IRENNRLRKEVESYLIDNLKSFAVAKSLKNSLMVEELFSIPSKEIELFIEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIDKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
     gene            complement(7497..8484)
                     /locus_tag="VQ548_001943"
                     /pseudo
     CDS             complement(7497..8484)
                     /locus_tag="VQ548_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT         2763 a         1212 c         1733 g         2776 t
ORIGIN      
        1 tataaaagtt atggatgagc gttttggaca ttctatttat atttatgaat cggaaacatt
       61 gtcggataat caagatgaaa tacctatcaa attaacgaat cattctttaa ttgaaccatt
      121 tgaattattg acagaaatgt atgctctgcc caaatattat gagaaagatc ctacacctgt
      181 attagcacca ttttacttta cattttttgg aatgatggtt gctgatttag gctatggttt
      241 actattgttt ttaggaacaa tgttagcatt aaaaattttt catctacctt cagaaactaa
      301 gagattttta aaattcttta atatattagg ggtagccgtt gcaatttggg gtggaatcta
      361 tggctcattt tttggatatg agttgccatt tcatctgata tctacaacct ctgatgtcat
      421 gattatatta gtagtgtcag ttgtgtttgg gtttattaca gtatttgcag gtttgttagc
      481 ttcaggacta caaaaagtaa gaatgaagaa atatgcagaa gcatataatt caggatttgt
      541 gtggtgtgtt attctgcttg gcttgttatt tattgctgtc ggaatgttga tgcctgatat
      601 gagactgtta tttgtattag ggaaatgggt atctattttt aatgctgtgg gaattttggt
      661 tgtttctatt attcaagcca aaagcttgtc aggtattgga gcaggattgt ttaatctata
      721 taacatttca tcttatatag gtgatttagt tagtttcact cgattgatgg cattaggatt
      781 atctggagca agtatagcat cagctttcaa tttaattgtt ggtttgtttc cgggaacatt
      841 ggctaaacta acaattggat tagtattatt cattctttta catgcgatca atatttttct
      901 atcgttacta tcaggatatg ttcatggagc acgtctgata tttgttgaat tttttggtaa
      961 gttttatgag ggtggaggaa aaccatttca acctttgaag gcttctgaga aatatattaa
     1021 ggttattaca aagaattaat ggaggatata tataatggaa catttagcaa cttatttttc
     1081 aacctatgga ggagctttct tcgctgcatt gggaattgta ttggcggttg gattaagtgg
     1141 tatggggtct gcttatggag ttggtaaggc tgggcaatct gccgcagctt tactgaaaga
     1201 acagccagaa aagtttgcct ctgctttgat attgcaatta ctgcccggaa cacaaggatt
     1261 atatggtttt gttattggaa ttttgatttg gttgcaatta actccagaac ttcctttaga
     1321 aaaaggcgtt gcttatttct ttgtagctct tccaattgct attgtaggat acttttcggc
     1381 taagcatcaa ggaaatgtag cagtagcggg aatgcaaatc ttggctaaaa gaccaaaaga
     1441 attcatgaag ggagcaattt tggctgccat ggtagaaacc tatgcaattc ttgcctttgt
     1501 cgtatcattc attttgaccc ttcgtgtata agaaattaat ttgctattca aaggaggtgt
     1561 ctaaatgagc aatttagaaa acttacgaga gtctgttatt gaacaagctc atgaaaaagg
     1621 gcgtatgaaa ttattggatt ccaaaaagaa gattgatgat gaatttgaaa tgcaaaagtc
     1681 ggtcattgta aagaaaaaag aagtggaaca tgaacgaaag ttaaaagaat tacaacagaa
     1741 atatcaaata atttttcaac aattaaaaaa taaggaacgc caatcaacgt tagtatcaaa
     1801 acagaaaata ttaaaagaac tttttcaatc tgctttaata gaaatggaat cttggagtgc
     1861 agataaagaa atggagttca tctatcgaat tctggaacga tattcacaac aagaggtcat
     1921 agtaactttt ggggagcgga ctttagctaa attcaatctg gaacaattag agaaattgaa
     1981 attctctttt ccaaatcatt tatttagtga acagcctatc tcaaatgaat caggcttact
     2041 tatttcaata ggtaaaattg atgataacta tttgtataaa acattaattg gatcgatttc
     2101 taaggaagaa agttcaagta tcgcaaatca aatttttatc aattaaggat gaaattggtt
     2161 aatccttctt agaaatttgg agtattccaa taaaattaga aaggtatttt atggatacta
     2221 atcttttttc aaaaataaat acgacgattt cggtaaaaga aaacgatttt attacagaag
     2281 ataaatttca aaaaattata caatccaaag atacggagac aatggcattt atcttagaag
     2341 caactcccta tcatttatcg attgacgttt tagaaaatcc tagtcagaca gagacttcgc
     2401 taatgacaaa attagtcaat gattatagat gggcctatgc tgaaagtccg tctaataaaa
     2461 ttgtgacttt atttgcttta cgatatgttt atcataatat caaagtttta ttaaaatcta
     2521 aggcggcaat taagaaagat ttttctaaat tattaattcc aatagggatt tttgatatag
     2581 aaagtttaaa acatttagtt tcttccttac attcagatac acttcctgat tttatggttc
     2641 atgaagtaga atcaatttgg aatgagtatg aaacttttaa taatattcgt gtacttgatg
     2701 tcggagctga tctagcatat tttaaacatc tgaaactttt atctaatgag ttagatgagg
     2761 tgctgtctca ggttattgtc gcaatgattg acttttataa tattattact gtaaaacgtg
     2821 gtttatctca aaataagagt catggggata ttttacaatt actttcagat gaaggaagta
     2881 tttctgctaa agaatttata tacattgtag aaaatcaaga aatatttgtg tggttcaata
     2941 aaataaatcc aagcttagat tcaatctttt caacttatga attgaagatg caggacgcaa
     3001 caatttcatc ttctgagtta gaatttttat gtgatttatt attgtataaa attttagatc
     3061 aaggaaggta caatgtagat gggccgttag tacttgctag atatttattg ggatgtgagt
     3121 ttgaagtaaa gaatctcaga atgattatat cagctcttca aaatacaatt ccctttggat
     3181 caataaaaga aaggatacgc ccgcattatg gaagctaata agtataaaat tggcataatt
     3241 ggtagccgtg atattatttt accctttagc atgattgggt ttgatatatt tcctgcctat
     3301 caagaacaag aagctataaa tactctaaga aaattagccc aatctgatta tggtgtcatt
     3361 tatatcactg aagacattgc ttcaatgata ttagatacaa ttcgccatta tgattctcaa
     3421 gttgtgcctg ctattatttt attaccgact cataaacaag gtttaaattt aggattaaaa
     3481 cgtatagagg ataatgtgga gaaagcagta ggacacaata ttttataata atgtacaaaa
     3541 ttgtctgtaa tattattcta taatttttgg acttagtaag gagaataact ttgactcaag
     3601 ggaagattat aaaagtatcg ggacctctag ttattgcatc aggtatgcag gaggctaata
     3661 ttcaagatat ttgccgtgta ggtaagctag ggttaatcgg tgaaattatt gaaatgagaa
     3721 gagatcaggc atctatccaa gtctatgagg aaacatctgg tcttggtccg ggagaacctg
     3781 ttgttacaac tggagaacct ctctcggttg aattaggacc aggattgatt tctcaaatgt
     3841 ttgatggcat acaacgccca ttagatcgat ttaaattggc tactcataat gattttctag
     3901 ttcgtggggt agaagttcca agtttggata gagatattaa gtggcatttt gattccacta
     3961 tagcaattgg tcaaaaagtg agtacgggtg atattctagg aactgtcaag gaaaccgagg
     4021 tagttaatca taaaattatg gttccttatg gagtatctgg cgaagtcgtt tctatcgcat
     4081 ctggcgattt tacaattgat gaagttgtat atgaaataaa aaaattggac ggtagtttct
     4141 ataaaggaac gcttatgcaa aaatggcctg ttcgcaaggc gcgtcctgtt tctaaacgtt
     4201 taatcccaga agaaccatta atcacaggtc aacgagttat tgatacattc tttccagtaa
     4261 ccaaaggggg agcagcagct gttcctggac cgtttggagc aggaaagaca gttgtacaac
     4321 accaagtagc taaattttcc aatgttgata ttgttattta tgtcggttgt ggagaacgtg
     4381 gaaatgaaat gacggatgta ctgaatgagt ttcctgagtt gattgaccct aataccggac
     4441 aatcaattat gcaacggaca gttctgattg ctaatacttc aaatatgcct gttgctgctc
     4501 gtgaggcttc aatttataca ggaattacca tggctgagta ttttcgtgat atgggctact
     4561 ctgtcgccat tatggctgat tcgacttcac gttgggcaga agcactacgt gaaatgtcag
     4621 gacgtctaga agaaatgcct ggtgatgagg gttatcctgc ttatctggga agtcgtatcg
     4681 ctgaatatta tgaaagagcg ggacgttctc aggttctagg gattccagaa cgtgaaggaa
     4741 ctattactgc tattggagct gtatcgccac ccggtggaga tatttcagaa ccagttactc
     4801 aaaacacttt acggattgtg aaagtttttt gggggcttga tgctccgttg gcacagagac
     4861 gtcattttcc tgcaattaac tggcttacat cttattcact ctataaagac agtgtgggaa
     4921 tttatataga tggtaaagag aagacagatt ggaatagtaa aataactcgt gcgatgaact
     4981 acttacaacg ggaatctagt ttagaggaaa ttgttcgtct tgttggaatt gattctctgt
     5041 ctgataatga acgactaacg atggaaattg ctaaacaaat tcgagaagat tatttgcaac
     5101 agaatgcttt tgattcagta gatacattca cttcgtttgc aaaacaagaa gcaatgctaa
     5161 gtaatatcct aacttttgct gatcaggcaa atcatgcttt agagttaggt tcttacttta
     5221 cagagattat ggaaggtacc gtggcagttc gagaccgtat ggcgcgaagt aaatatgttt
     5281 cagaagatag attagatgaa atcaaaatta tttcaaatga gattacacat caaattcatt
     5341 tgatattaga aacaggaggt ctataaatga gtgttataaa agaatacaga actgctagtg
     5401 aagttgttgg gcctcttatg attgttgaac aagtaaataa tgtgtcttac aatgagttag
     5461 ttgaaattca acttcataat ggagaaattc gtcgtggaca agttttagag attcacgaag
     5521 ataaagcaat ggttcaactt tttgaaggat ctagtggaat aaatttagaa aagtctaaaa
     5581 ttcgttttgc tggtcatgca ctagaattgg ctgtatctga ggatatggtt ggtcgtattt
     5641 ttaatgggat gggaaaacca attgatggtg gaccagattt aattccagag aaatatttag
     5701 atattgatgg tcaagctatt aatcctgtat ctagagatta tccagatgaa tttattcaga
     5761 cagggatctc ctctattgat catttgaata ctcttgtacg tggtcaaaaa ttaccagtat
     5821 tttcaggttc gggcttacct cataatgaat tagcagctca gatagcaaga caagcgactg
     5881 ttttaaattc tgatgaaaat tttgcggttg tatttgcagc aatgggtatt acttttgaag
     5941 aagctgagtt ttttatggaa gaactcagaa aaacaggagc gatcgatcgt tcagtcttat
     6001 ttatgaactt ggcaaatgat cctgcaattg agcgtattgc aactccccgc attgctttaa
     6061 ccgcggcaga gtatctagct tttgaaaaag atatgcacgt tctagttatc atgacggata
     6121 tgactaacta ttgtgaagcg ttacgtgaag tctcggcagc gcgccgtgaa gttccaggta
     6181 gacgaggcta tccgggatat ttatatacaa atttatcaac tctatatgaa agggctggtc
     6241 gcttagttgg taaaaaaggt tcagtgacac agattcctat tttaacaatg ccagaagatg
     6301 acataacaca tccaattcct gatttaactg gatacattac tgaagggcaa attattttgt
     6361 ctcatgagtt gtataatcaa ggttatcgtc caccaatcaa tgttttatct tctctctctc
     6421 gattaaaaga taagggatct ggagaaggta aaactcgtgg agatcatgct ccaactatga
     6481 atcaactgtt tgcagcctat gcccaaggga aaaaggttga agagttagca gtagtattag
     6541 gagaatcggc tttatctgat gtagataaat tgtatgtgag atttacaaag cgttttgaag
     6601 aagagtacat caaccaagga ttttataaaa atcgaaatat agaagatacg ttgaatcttg
     6661 ggtgggaatt actatcaatt cttcctagaa cagagttaaa acgtatcaaa gatgatttgc
     6721 ttgataaata tttacctttg gtagaagttt aatccagaaa tggagtgatt atctatggta
     6781 cgtttgaatg taaaaccaac tcgtatggaa ttgaataact taaaggaacg tttgaaaaca
     6841 gctgaacgtg gacataagtt attaaaggat aaaagagatg aattgatgag gcgatttatt
     6901 tctttgattc gtgagaataa tcgacttcgg aaagaagtag aaagttatct aattgataat
     6961 ctaaaatctt ttgcagttgc taaatcatta aagaactctc taatggtgga ggaattattt
     7021 tcaattccat cgaaagaaat tgaattattt attgagaaag aaaatatcat gagtgtaaca
     7081 gttcctagaa tgcatatgaa tattacttct caaaatgaga acagtgaata cagctattta
     7141 tcttctaata gtgaaatgga tgatgtattt gctacaatga atagtttaat tgataaatta
     7201 ctaagactgg cagaagttga aaaaacgtgt cagttaatgg ctgatgaaat agaaaaaaca
     7261 cgtagacgtg taaatggttt agaatattcg attattccaa acttgtcgga aactattcat
     7321 tatatagaat tgaaactaga ggaggcagaa agagccaatt tagttcgtat tatgaaagtg
     7381 aagtagttcc tttatttaga tttttaatta gatgaacaaa tatcagcttg gataaggcgg
     7441 taagcctttc taagcttttt taggctcttt gtcaactgta gtgggttgaa aaaaagctaa
     7501 gctcgagaaa ggacaaattt cgtcctttct tttttgatat tcagggcgat aaaaatccgt
     7561 tttttgaagt tttcaaagtt ccgaaaacca aaggcattgc gcttgataag tttgatgaga
     7621 ttattggtcg cttccaattt ggcgttagaa tagtgtagtt gaagggcgtt gacgattttc
     7681 tctttgtcct ttagaaaggt tttaaagaca gtctgaaaaa gaggatgaac ctgctttaga
     7741 ttgtcctcaa tgagtccgaa aaatttctcc ggttccttat tctgaaagtg aaacagcaag
     7801 agttgataga gctgatagtg atgtttcaag tcttgtgaat agctcaaaag cttgtttaaa
     7861 atctctttat tggttaaatg catacgaaaa gtagggcgat aaaaatgttt atcgctgagt
     7921 ttacgactat cctgttgtat gagcttccag tagcgcttga tagccttgta ttcatgagac
     7981 tttcgatcca attgattcat gatttgaaca cgcacacgac tcatagcacg gctaagatgt
     8041 tgtacaatgt gaaagcgatc caacacgatt ttagcacatg ggaaaagttg tctagctaag
     8101 tcatagtaag gactaaacat atccatagta ataattttga cgcgacatcg gacggctcta
     8161 tcatatttaa gaaagtgatc tcggatgaca gcttgtgttc taccctcaag aacagtgatg
     8221 atattgagat tgttaaaatc ttgcgcaatg aagctcatct ccatctcccg attgaaacag
     8281 tcactccccg gactgtttca acgtcccaag acataatctc aggcagattt ctaaaattac
     8341 actcaaagtg gaagtcattg agcttacgaa taacagttga agttgagatg gaaagctgat
     8401 gggcaatatc agtcatagaa atcttttcaa ttaacttttg agcaatcttt tggttgatga
     8461 tacgagggat ttggtgatta ttct
//
LOCUS       DAVBEM010000070         8109 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVBEM010000070 DAVBEM010000000
VERSION     DAVBEM010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8109
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.070"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            120..497
                     /locus_tag="VQ548_001944"
     CDS             120..497
                     /locus_tag="VQ548_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET2654738.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIALV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            732..2123
                     /locus_tag="VQ548_001945"
     CDS             732..2123
                     /locus_tag="VQ548_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HET2654739.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIDQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            2237..3079
                     /locus_tag="VQ548_001946"
     CDS             2237..3079
                     /locus_tag="VQ548_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HET2654740.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            3352..4113
                     /locus_tag="VQ548_001947"
     CDS             3352..4113
                     /locus_tag="VQ548_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET2654741.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            4483..5400
                     /gene="glyQ"
                     /locus_tag="VQ548_001948"
     CDS             4483..5400
                     /gene="glyQ"
                     /locus_tag="VQ548_001948"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HET2654742.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            5660..7696
                     /locus_tag="VQ548_001949"
     CDS             5660..7696
                     /locus_tag="VQ548_001949"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HET2654743.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSELFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            7738..7995
                     /locus_tag="VQ548_001950"
     CDS             7738..7995
                     /locus_tag="VQ548_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HET2654744.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
BASE COUNT         2555 a         1431 c         1794 g         2329 t
ORIGIN      
        1 gctttctttt ccgaataaat agatagaagc atagaatcta gcaaacctag atttaaaaat
       61 gtgctataat agaaggagga aaaggaggat tctcagacat ccaggtatca gcccaactaa
      121 tgatttgtca atttatccgc gatatgctgg acttgccagc aaaaaatgtg acgattttgg
      181 agggaagtaa cattcacgtc ttgccttcca tgccctactc agcgcaagat ttctatacta
      241 gtatagacgt cttggcggag ttagataatg gaatccaagt tatcatcgaa attcaggttc
      301 atcatcagaa ttttttcatc aatcgcctat gggcttatct gtgcagtcag gttaatcaaa
      361 acctagaaaa aattcgccaa cgtgaaggtg atacccacca gagctacaaa caaatcgcac
      421 tagtatacgc tatcgcaatt gtcgatagta attacttctc agatgaccta gcttttcata
      481 gttttatagt aaaatgaaat gagaacagga caaatcgatc aggacagtca aatcgatttc
      541 taacaatgtt ttagaagtat aggtctacta ttctagcttc aatctactag aaattccata
      601 gatagaaaac tacataatct ctacagatac ggatgttgga gttgatgtaa gatgctttgg
      661 cttgctagag gaattgtgga ttgccaaatt gtatcattga aattattgct caaatttgtt
      721 atgatataaa tatgaataaa agtagactag gacgtggcag acacgggaaa acgagacatg
      781 tattattggc tttgattggt attttagcaa tttctatttg cctattaggc ggatttattg
      841 cttttaagat ctaccagcaa aaaagttttg agcaaaagat tgaatcgctc aaaaaagaga
      901 aagatgatca attgagtgag ggaaatcaga aggagcattt tcgtcagggg caagccgaag
      961 tgattgccta ttatcctctc caaggggaga aagtgatttc ctctgttagg gagctgataa
     1021 atcaagatgt taaggacaag ctagaaagta aggacaatct tgttttctac tatacagagc
     1081 aagaagagtc aggtttaaag ggagtcgtta atcgtaatgt gaccaaacaa atctatgatt
     1141 tagttgcttt taagattgaa gagactgaaa agaccagtct aggaaaggtt cacttaacag
     1201 aagatgggca accttttaca cttgaccaac tgttttcaga tgctagtaag gctaaggaac
     1261 agctgataaa agagttgacc tccttcatag aggataaaaa aatagatcaa gaccagagtg
     1321 agcagattgt aaaaaacttc tctgaccaag acttgtctgc atggaatttt gattacaagg
     1381 atagtcagat tatcctttat ccaagtcctg tggttgaaaa tttagaagag atagccttgc
     1441 cagtatctgc tttctttgat gttatccaat cttcgtactt actcgaaaaa gatgcggcct
     1501 tgtaccaatc ttactttgat aagaaacatc aaaaagttgt cgctctaacc tttgatgatg
     1561 gtccaaatcc agcaacgacc ccgcaggtat tagagaccct agctaaatat gatattaaag
     1621 cgactttctt tgtgcttggg aaaaatgttt ctgggaatga ggacttggtg aagaggataa
     1681 aatctgaagg tcatgttgtt ggaaaccata gttggagcca tccgattctc tcgcaactct
     1741 ctcttgatga agctaaaaag cagattactg atactgagga tgtgctaact aaagtgctgg
     1801 gttctagttc taaactcatg cgtccacctt atggtgctat tacagatgat attcgcaata
     1861 gcttggattt gagctttatc atgtgggatg tggatagtct ggactggaag agtaaaaatg
     1921 aagcatctat tttgacagaa attcagcatc aagtagctaa cggctctatc gttttgatgc
     1981 atgatattca cagtccgaca gtcaatgcct tgccaagggt cattgagtat ttgaaaaatc
     2041 aaggttatac ctttgtgacc ataccagaga tgctcaatac tcgcctaaaa gctcatgagc
     2101 tgtactatag tcgtgatgaa taagcaagaa aaaataggtc tgttagatat ttgacagact
     2161 tattttttac agaatatagt actacttaaa aaatgtttta tgctataatt gatgaataaa
     2221 atagaaggag aagcatatga atacctatca attaaataat ggagtagaaa ttccagtatt
     2281 gggatttgga acttttaagg ctaaggatgg agaagaagcc tatcgtgcag tgttagaagc
     2341 cttgaaggct ggttatcgtc atattgatac ggcggcgatt tatcagaatg aagaaagtgt
     2401 tggtcaagca atcaaagata gcggagttcc acgtgaagaa atgttcgtaa ctaccaagct
     2461 ttggaatagt cagcaaacct atgagcaaac tcgtcaagct ttggaaaaat ctatagaaaa
     2521 actgggcttg gattatttgg atttgtattt gattcattgg ccgaacccaa aaccgctcag
     2581 agaaaatgac gcatggaaaa ctcgcaatgc ggaagtttgg agagcgatgg aagacctcta
     2641 tcaagaaggg aaaatccgtg ctatcggcgt tagcaatttt cttccccatc atttggatgc
     2701 cttgcttgaa actgcaacta tcgttcctgc ggtcaatcaa gttcgcttgg cgccaggtgt
     2761 gtatcaagaa caagtcgtag cttactgtcg tgaaaaggga attttattgg aagcttgggg
     2821 gccttttggt cagggagaac tatttgatag caagcaagtg caagaaatcg cagcaaatca
     2881 cggaaaatcg attgctcaga tagccttggc ctggagcttg gcagaaggat ttttaccact
     2941 tccaaaatct gtcacaacct ctcgtattca agctaatctt gattgctttg gaattgaact
     3001 gagtcatgag gagagagaaa ccttaaaaac gattgctgtt caatcgggtg ctccacgagt
     3061 tgatgatgtg gatttctaga aaatcataaa aagaattgta cattattcta atttttgata
     3121 taatagtcag caggaaagaa agtcttatgg cgttcttcaa gcgagcttgg gatagtggga
     3181 gccaagtagg gcaaaataat gagctggcgc tttctgtagt attttcaaaa acaatgaagt
     3241 aataaattag ggtggaaccg cgtttctgac gcccctaggt taaatcaacc taggattgtc
     3301 ggacgcggtt cttttgctta ttcagtctat tgtgtgaaag aaaggagagc cgtggacaac
     3361 ctttatcttg taaaagacga tagtcaacta gctacatttc gtgattttgt agtaagaaat
     3421 actgaaaagt tgaaagatta tcaatctttt ttaaagaatg aacttgcagt ctgtgattta
     3481 ccgcaagccg ttatttggtc agattttaat gctgctacac agattattag ggaaagcgct
     3541 gttccagcct atacaaataa tagacgaatg gttatggcgc ctgatttagc tgtttggaaa
     3601 gagttgtatt tgtatcaatt gatggactac gagtgttctc agcaaactca agcaatagaa
     3661 agtcactatc attctttatc tgaaaatttc ctcttacaga ttgtaggaca tgagttagct
     3721 cattggtcgg agcatttttt agatgatttt gatggttatg actcttatat ctggttcgaa
     3781 gaggggatgg ttgaatatat tagtcgcaag tatttcttga cagaagagga atttcaagcg
     3841 gaaaaaattt gtaatcaatc tctcgtagaa ctttttcaga agaagtatgg ttggcattca
     3901 ttgaatgatt ttggttcttc gacttatgat aagaactatg caagtatttt ttatgaatac
     3961 tggcgcagct ttttgacagt agataagttg gtagaaaatt taggtagtgt acaagcggtc
     4021 ttagattctt atcatttatg ggcaaataca gaaaaaactt ttcccttgtt agattggttt
     4081 gttcagcaga aattaattga aaaagaaata taaaaactaa aggagtaaac aatgtctaag
     4141 aaattgacat ttcactgcgt cagtggcaga aacctcctta cagtcggact gccccacgct
     4201 cagcactaga gtgcctgagc tagacgcagt actaactcgt cttgcctcgt atgatcgacg
     4261 aggcagactc atgtcgcaag taattatttt ttattaagga gtaaacaatg tctaagaaat
     4321 taacatttca ctgcatcagt ggcagaaacc tccttacagt cggactgccc cacgctcagc
     4381 accctagtgc tgagctagac gcagtactaa ctcgtcttgc ctcgtataat cgacgaggca
     4441 gactcgtgtc gcaagaaatc attttttatt aaggagtaaa caatgtctaa gaaattaaca
     4501 tttcaagaaa ttattttgac tttgcaacaa ttttggaatg accaaggttg tatgcttatg
     4561 caggcttatg acaatgaaaa aggtgcgggg acaatgagtc cttacacttt ccttcgtgct
     4621 atcggacctg agccatggaa tgcagcttat gtagagccat cacgtcgtcc tgctgacggt
     4681 cgttatgggg aaaaccctaa ccgtctctac caacaccacc aattccaggt ggtcatgaag
     4741 ccttctccat caaatatcca agaactttac cttgagtctt tggaaaaatt gggaatcaat
     4801 cctttggagc acgatattcg ttttgttgag gacaactggg aaaacccatc aactggttca
     4861 gctggtcttg gttgggaagt ttggcttgac ggaatggaaa tcactcagtt cacttatttc
     4921 caacaagtcg gtggattggc aactggccct gtgactgcgg aagttaccta tggtttggag
     4981 cgcttggctt cttacattca agaagtagac tctgtctatg atatcgagtg ggctgatggt
     5041 gtaaaatacg gagaaatctt tatccagcct gagtatgagc actcaaaata ttcatttgaa
     5101 atttcggacc aagaaatgtt gcttgaaaac tttgataagt ttgaaaaaga agctggtcgt
     5161 gcattagaag aaggcttggt acaccctgcc tatgactatg ttctcaaatg ttcacatacc
     5221 tttaatctgc ttgacgcgcg tggtgccgta tctgtaacag agcgtgcagg ctatatcgct
     5281 cgtatccgta acttggcccg tgttgtagcc aaaacctttg ttgcagaacg caaacgccta
     5341 ggttacccac ttttggatga agaaacacga gttaaacttt tagcagaaga cgcagaatag
     5401 tgagtaatac tgtactctaa aatcgttaga ggcaagtcga agacttgcta gagggatatg
     5461 caccgccgta ctgttatgtg gggatttttg aaaccttagg ttcaaaaatc agtcagctaa
     5521 atccactttg atgagattgt tggaaatctt gataaattta gcattggatt tccatacaga
     5581 ctcacagagt tagttagcga cgtccccagt acctaaggtg catatcaaaa aagattgaag
     5641 aaaatgtaaa ggaaaaaaca tgacaaaaaa cttattagta gaactcggtc ttgaagaatt
     5701 accagcctat gttgtcacac caagtgaaaa acaactaggc gaaaaaatgg cagccttcct
     5761 caaggaaaac cgcctgtctt ttgaagccat tcaaaccttc tcaacaccac gtcgtttggc
     5821 tgttcgtgtg actggtttat cagacaaaca gtctgatttg acagaagatt tcaagggacc
     5881 agcaaagaaa attgccttgg atagtgatgg aaactttacc aaagcagctc aaggatttgt
     5941 ccgtggaaaa ggcttgactg ttgaagatat cgaattccgt gaaatcaagg gtgaagaata
     6001 tgtctatgtc actaaggaag aagttggtca agcagttgaa gccattgttc ctggtgttgt
     6061 agatgtcttg aagtcattga ctttccctgt cagcatgcac tgggctggaa atagctttga
     6121 atacattcgt cctgtccaca ctttaactgt tctcttggat gagcaagagt ttgacttgga
     6181 tttccttgat atcaagggaa gtcgtgtgag ccgtggccat cgtttcttgg ggaaagaaac
     6241 caaaattcag tcagcattga gctatgaaga agaccttcgt aagcagtttg taatcgcaga
     6301 tccatgtgaa cgtgagcaaa tgattgttga ccaaatcaag gaaattgagg caaaacatgg
     6361 tgtacgtatc gaaattgatg cggatttgct gaatgaagtc ttgaatttgg ttgaataccc
     6421 aactgccttc atgggaagtt ttgatgctaa ataccttgaa gttccagaag aagtcttggt
     6481 gacttctatg aaggaacacc agcgttactt tgttgttcgt gatcaagatg gaaaactctt
     6541 gccaaacttc atttctgttc gtaacggaaa cgcagagcgt ttgaaaaatg tcattaaagg
     6601 aaatgaaaaa gtcttggtag cccgcttgga agacggagaa ttcttctggc gtgaagacca
     6661 aaaattggtg atttcagatc ttgttgaaaa attaaacaat gtcaccttcc atgagaagat
     6721 tggttccctt cgtgaacaca tgattcgtac gggtcaaatc actgtacttt tggcagaaaa
     6781 agctggtttg tcagtggatg aaacagttga ccttgctcgt gcagcagcca tttacaagtt
     6841 tgacttattg acaggtatgg ttggtgaatt tgacgaactc caaggaatta tgggtgaaaa
     6901 atacaccctt cttgctggtg aaactccagc ggtggcagct gctattcgtg aacactacat
     6961 gcctacatca gctgaaggag aacttccaga gagcaaggtc ggcgcagttc tagccattgc
     7021 agacaaattg gatacgattt tgagtttctt ctcagtagga ttgattccat caggttctaa
     7081 tgacccttat gcccttcgtc gtgcaactca aggtgtggtt cgtatcttgg atgcctttgg
     7141 ttggcacatt gctatggatg agctgattga tagcctttat gcattgaaat ttgacagttt
     7201 gacttatgaa aataaagcag aggttatgga ctttatcaag gctcgtgttg ataagatgat
     7261 gggctctact ccaaaagata tcaaggaagc agttcttgca ggttcaaact ttgttgtggc
     7321 agatatgttg gaagcagcaa gtgctctcgt agaagtaagc aaggaagaag attttaaacc
     7381 atctgttgaa tcactttctc gtgcctttaa cctggctgag aaggcagaag gggttgctac
     7441 agttgattca gaactatttg agaatgacca agaaaaagct ttggcagaag cagtagaaac
     7501 actcgtttta tcaggacctg caagtcagca attgaaacaa ctctttgcgc ttagcccagt
     7561 cattgatgct ttctttgaaa atactatggt aatggctgaa gatcaggctg tccgtcaaaa
     7621 tcgtttggca atcttgtcac aactaaccaa gaaagcagct aagtttgctt gttttaacca
     7681 aattaacact aaataaaatt tgataaacgg actttatctt attacaaagg agaagaaatg
     7741 gatccgaaaa aaattgctcg tatcaatgag cttgctaaaa agaaaaaaac agaaggctta
     7801 acaccagaag aaaaagtgga acaagccaaa ctacgtgagg agtacatcga aggttatcgc
     7861 cgcgctgttc gtcaccacat tgaaggaatc aaaattgtgg acgaagaagg aaacgatgtt
     7921 acaccagaaa aactacgcca agtacaacgt gaaaaaggat tacatggccg tagtcttgat
     7981 gacccaaatt cataatatgt actctttctt ttaacaaaga tagatgaaac gataacaaag
     8041 agactagcag tttgtgtttg ctagtctttt ttcgctaaaa aaggaaccat aatggttcct
     8101 aaaaactat
//
LOCUS       DAVBEM010000071         7893 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVBEM010000071 DAVBEM010000000
VERSION     DAVBEM010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7893
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.071"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            101..1078
                     /locus_tag="VQ548_001951"
     CDS             101..1078
                     /locus_tag="VQ548_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2654745.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGVRFEAEK"
     gene            1075..2157
                     /locus_tag="VQ548_001952"
     CDS             1075..2157
                     /locus_tag="VQ548_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2654746.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFELLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(2221..3270)
                     /locus_tag="VQ548_001953"
                     /pseudo
     CDS             complement(2221..3270)
                     /locus_tag="VQ548_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(3654..4850)
                     /gene="tuf"
                     /locus_tag="VQ548_001954"
     CDS             complement(3654..4850)
                     /gene="tuf"
                     /locus_tag="VQ548_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET2654747.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(5761..6630)
                     /locus_tag="VQ548_001955"
     CDS             complement(5761..6630)
                     /locus_tag="VQ548_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET2654748.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(6853..7533)
                     /locus_tag="VQ548_001956"
     CDS             complement(6853..7533)
                     /locus_tag="VQ548_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2654749.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPTPDK
                     PTPEPGTPKAETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAGLGLGF
                     FKKKEDEK"
     gene            complement(7491..>7893)
                     /locus_tag="VQ548_001957"
     CDS             complement(7491..>7893)
                     /locus_tag="VQ548_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET2654750.1"
                     /translation="FKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANYYKE
                     GSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPANAY
                     QKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
BASE COUNT         2299 a         1646 c         1489 g         2459 t
ORIGIN      
        1 aaagctaata gcttatttga aattttctcc tctctgttgg atagtcccgt ctatctatgt
       61 tataatgaaa gaaggattta aaatcggaaa aggagtattt atgctaaaat taggtgtcat
      121 cggaactggc gctatcagcc atcatttcat agaagcagcc cataccagtg gagaatacca
      181 actggtcgca atctattcta gaaaactaga aactgcagca acctttgctt ctcgctatca
      241 gaatatccaa ctattcgatc aattagaagt cttcttcaaa tcttcttttg atttagtcta
      301 tatcgccagt ccaaactcct tacattttgc tcaggcaaaa gctgccttgt ctgctggtaa
      361 acatgttatt cttgaaaagc cagctgtcac tcaaccacaa gaatggtttg atttgattca
      421 aacagctgaa aaaaataact gttttatctt tgaagcagct cgtaattatc acgagaaagc
      481 ctttactact atcaaaaact ttttagcaga taagcaagtg ttaggagcag atttcaacta
      541 tgccaaatac tcttccaaga tgcctgactt attggctgga caaacaccaa atgtcttttc
      601 agaccgtttt gctggtggag ccctcatgga tttggggatt tatcccctct atgctgctgt
      661 tcgtcttttt gaaaaagcta atgacgcgac ttaccatgct caacagcttg acaatagcat
      721 tgacctaaat ggagatggta tcctcttcta cccagactat caagttcaca tcaaggctgg
      781 aaaaaacatc acttccaatc ttccttgcga gatttataca acagatggaa ccttgactct
      841 caacacgatt gagcatattc gctcagctat ttttaccgac caccaaggaa atcaagtcca
      901 gcttcctatc caacaggctc ctcatacgat gactgaggaa gtcgctgcat ttgcacacat
      961 gatccagcaa ccagatctga atctctacca aacttggctg tatgatgcag gctctgttca
     1021 tgagctacta tataccatgc gccagactgc tggcgttaga tttgaggcag aaaaatgaaa
     1081 accaaactac cgactgaatg gcaagaactg agtgaccaac tcggtttcca agaattcacc
     1141 cccattcaaa ctcaactatt tgagctcctt cttgctggag aaaacctcct aggagtgagc
     1201 caaaccggaa ctggtaagac cctagcgtat ctcctaccaa gtcttctcag actacaaaag
     1261 aaaaaagccc aacaactctt gattctagca ccaaacacgg aacttgctgg acagattttt
     1321 gatgtatgta aaacgtgggc agaagctatc ggattgactg ctcaactctt cctttcaggt
     1381 tcaagtcaga aacgacaaat tgaacgtctt aaaaaggggc cagaaattct gattggaact
     1441 cctggccgta tctttgaact cattaaactt aaaaaaatca agatgatgaa tgtggaaacc
     1501 atcatcctgg atgaatttga ccaattacta gatgattctc agattcactt tgtagagaaa
     1561 atcactcact acgcacctcg tgaccaccaa ctggtctaca tgagtgccac gaccaagttt
     1621 gaccaagaaa agattgtgcc gaatacacgc actattgatc tctctgatca aaaattggac
     1681 aatatccagc atttctacat gcaggtagac caacgtcatc gagtggatat gctacgaaaa
     1741 ctggctcatg tagaggattt ccgtggtcta gtcttcttca atagcctgtc agaccttggg
     1801 aatgccgagg aaaaactaca gtatcgtgat atattggctg tttccctcgc tagtgatgtt
     1861 aatgttaaat ttagaaaaat catcttagaa aagtttaaag ataaccaact aaccctgctt
     1921 cttgcaactg accttttggc tcgtggaatt gatatcgata gcctagaatg tgtcgtaaac
     1981 tttgatattc ctagagatag cgaaacctac acacaccgtg ctggccgtac tggtcgtatg
     2041 ggcaaggaag gttatgttat cactctcgtc actcatccag aagaaatcaa aaaacttaaa
     2101 aagtttgcaa gtatccgaga aattgtccta aaaaaccaag aactctatat caaataaagc
     2161 cccattgctc tatacacatc cagtgtatgg agctttttta taagcaattc aattttatac
     2221 tcatctgctt tcaaaaagca ttctagtcca tctccgatta acgatggact ttatcacctc
     2281 cttctccaat ccttgtatga catcttgaag ttgattcatg acatcttcca aaattcgaaa
     2341 ggctttattc ttaaatccac gtttacgaat ctctttccac acttgttcaa tggggttcat
     2401 ctctggtgtg tatggaggaa taaatgcaaa accaatatta gtcggaatct ttaagatact
     2461 tgatttatgc catatagcat tgtccataac gagtaaaaaa taatcatctg gataagcttg
     2521 tgaaagcttt tctaaaaagg cgttcatcca ctcagtatta catctaccag ctattaagaa
     2581 aaatgattcg cctgtatggg catcaacagc tccataacaa tagcgaaatt ctcgtatata
     2641 gtgactatgg atatgtggac ctactcctat tggagcccaa caagatccca gtttactgat
     2701 tctaccgaaa ccagcctcat cttggtacat caagcgaacc ttacgaaaac gtctactata
     2761 tttaaaacgc tttcttgtct tcttgaattg agattttatt tttagacgcg acaatggttt
     2821 gagcgtctgc tttcttagga tgttctggac gtggcataat atttcgccaa ccatggcgct
     2881 tcaacagttg atagaaggca tcacgtgtgt aggaacgacc taactccttt ttataagcct
     2941 gaaataaggc atcaattgta acaaattctc ctgcctctgc agccttcaaa tggcgggcaa
     3001 gaaagacttt ctcttcctca actgtcatat atgcatggtt acgaccacca cgtgtttctt
     3061 gaaggagaga gtcgagtccg aactcctcat atttttttac atttcgccaa atcattgttt
     3121 gattacagtc taaaagttct ataatctctt tataagattt gcccatatca gacgaaatag
     3181 aacgatttga agacgtttat gatatttagc tgtacgagag tcttttaaaa gtgttttgat
     3241 ggtttggatt tcttctttaa ttgatttcat attactattg tataatgctt tttgatttta
     3301 gtctagtatt atactcttcg aaaatctctt caaaccgcgt cagcttcgcc ttgtcgtata
     3361 gatgttactg acttcgtcag ttctatctac aacctaaaaa cagtgttttg agcagtctgt
     3421 agctaacttt ctatagtaaa atgaaataag aacaagacaa atcgatcagg acagtcaaat
     3481 cgatttctaa caatgtttta gaagtaaatg tgtactattc tagtttcaat atattatagt
     3541 ttgctctttg attttcattg agtattagtt caatatctaa aaaaagaacc ttgccaagca
     3601 agattctttt agtgtctgac ttaaataatt gttcttctgg gaactaaatc gaattaagct
     3661 tcgatttctg taaccatacc tgaaccaaca gtacgtccac cctcacggat agagaatgta
     3721 gtaccttgtt ctacggcgat tgggtgaatc aactcaacgt cgattgtcac gttatcacca
     3781 ggcattacca tttcagtacc tgctggaagt tcgattgaac ctgtaacgtc agtagtacgg
     3841 aagtagaatt gtggacggta gttgttgaag aatggagtgt gacgtccacc ttcttcttta
     3901 gtaaggatgt agacttcacc tttgaattta gtgtgtgggt tgattgaacc tggtttagcg
     3961 ataacttgtc cacgttcgat ttcatcacgt tgaacaccac gaagaaggac acctacgtta
     4021 tctccagcaa gaccttcgtc aagttgttta cggaacattt caacaccagt aacaactgct
     4081 ttttgagttt cttctttgat accaacgatt tcgatttcgt cgttgacttt aacgatacca
     4141 cggtcgatac gtcctgaagc aactgtacca cgtccagtga ttgagaatac gtcctcgact
     4201 ggaagaagca atggtttgtc agtgtcacgt tctggttctg ggatatactc atcaactgtg
     4261 ttcatcaatt ccataacgat gtcttcgtat ttagagtcac cttcaagagc tttaagtgct
     4321 gaaccttgga taactggaag atcgtcacct gggaagtcgt attctgacaa taggtcacgg
     4381 atttccattt caaccaattc aagcaattct tcgtcgtcaa ccaagtcaac tttgttcatg
     4441 aagacgataa ggtgtttaac accaacctga cgtgaaagaa ggatgtgctc acgagtttgt
     4501 ggcattggtc cgtcagttga agctactaca aggatagctc cgtccatttg agcagcacca
     4561 gtgatcatgt ttttaacgta gtccgcgtgt cctggagcgt cgatgtgagc gtagtgacgt
     4621 ttttcagttt cgtactcaac gtgcgcagtg ttgatagtga taccgcgttc gcgttcttct
     4681 ggagcagcat cgatagacgc atagtcttta ggttggttaa ctgatgaagg caagcgacgt
     4741 gccaaaacag ttgtgatagc tgcagttagg gtagttttac cgtggtcaac gtgtccgata
     4801 gtaccaatgt taacgtgtgg tttactacga tcgtattttt cttttgccat ttgagtaaaa
     4861 gcctccaata aaatatattt tatagataga cagtaggcaa tacagtctaa ctttccttac
     4921 tattttatca aatttcagct aaattgcaag tgttttacaa cgtttttgtg aattattctt
     4981 ggtaaaaatt taactaatta atagaaagta ctaaatagac ttatccttca aggagttttc
     5041 agcattatcc atccactcac ttgctgaaaa tgtaaacagt ctctggttta tatagtaaaa
     5101 tgaaacaaga atagagcaaa tcgatcagga cagtcaaatc gatttctaac aatgttttag
     5161 aagtagatgt gtactattct agtttcaatc tactatacaa cctcaaaact gtgttttgaa
     5221 caacctgcgg ctagcttctt agtttgccct ttgattttca ttgagtataa aattgcagat
     5281 aaaacgataa caatcatagg actcagcaga gtcaatgtag gtcgaagaat agccccccta
     5341 atcgcttatt ttatagcaaa atgaaataga aactgaacat tttgttgagg aaggtaaatc
     5401 aattcctcac aatgtttgag aaagaaggga ggactattcc aacttcaacc cactataaag
     5461 cagacttaca agatagggaa cccatctccg ataatatata gtagaatgaa aactgcacaa
     5521 tttgattgga gaattcaaac caatttctaa caatgtttta gaaacaaggg tctattattt
     5581 caactgcaac ctactatagc ccattgaagc tggaatagcc cactgagact tctaaaccac
     5641 tgctggagag gagtttgttt agagtttctt tcatttccct aaaaaatcaa aaagagagaa
     5701 ccagtctgat cctctcttac ttatagatgg tgctcactca aatgttaaag gagctatttc
     5761 ttagagataa aggaatttga atacagctac tgccgcaatt gctgctgcga taggtgctac
     5821 tactggtacc caagaatacc accattttga atcgccttta tgctcaccaa gaactgattt
     5881 tggaaggaaa gcatgaagga gacgtggtcc caagtcacgg gctgggttca aggcaggtcc
     5941 tgtaggtcct ccaagtgatg ttaccaaagc cataacgagg aatccaagtg ccaagtgagc
     6001 cacagaaagt cctgaagcag tgtgtggagc cacctgtgct ttaatagcca agtcagaaaa
     6061 atcaactgtt tgtcctgctt ctattgcctt ttgtttcatg aattgaagca cttcagcacc
     6121 aaagaagttt ttagtcaaac caagagctgc aaagaacaaa acaaatgaac caacaaactc
     6181 attaatcaaa ccattgacag ttgctgcata gcgactttct tttgtaccat ggtcaatact
     6241 tgaaatagtt gagaaagttc ccaagatgtt atttggtttt tcagttttca agtagaatgg
     6301 acggtatgtt gccacaacta aggcttggcc aaagatagcc cccaagactt gcgcgataat
     6361 gtaaggtacc acttgtgccc aagggaaaag accgctaact gcaagcccta gagtgaaagc
     6421 agggttgatg tgattcccag atacgttacc aaacatcaag gctgggatca taacccccat
     6481 accataacca acagcgatga cgatccagcc actttggtga cctttcgtac ctttaagttc
     6541 aacgttggca actgcaccat tcccaagaat gatcaaaatg gcagttccca aaaattcagt
     6601 ggcatacttc agtgcccatg tgaaatccat ttgctagatt ctccttaaaa ttttttagat
     6661 attccttatt ttatcaattt ttaccctatt tagcaactga tttctggaaa tatttttaaa
     6721 aaaataggat tcatagtttc ccagttcaac gtacttgtaa gcgtttttat tcttcacgaa
     6781 agacctcatt ctcaaaacca ggaaaaagcc cacatctgtg atcttttcct ggttcctaga
     6841 ttctaaaatc tattattttt catcttcttt tttcttgaag aatcctaatc ctagaccagc
     6901 taacaaggtc atgataccag cactagccaa ggtagcatta gcttctgtac ctgtgtttgg
     6961 caattcctct ctcttacctg tctcataagt cggaacttct gggtctggat tcactggagt
     7021 ttcagctttt ggagtacctg gttctggagt tggtttatct ggtgttggag tctcttgatt
     7081 tggtagttct gggtttggtg tcggaacact tggatgctct ggatttggtt gtgggattgg
     7141 tttttctgga gtcggttcac ctggagtacc tggttcctga ggacttggaa tttctggttt
     7201 ttctggagtt ggtttatctg gtgttgataa acggtcatac cttaccgtta tttctttatc
     7261 actagagtct gacgtaactt cttgtgattc aactgttgga atatctggat ctttgtactt
     7321 gtcaatctta ccagatataa cctcgtccca gtttcctgtt gtccattcac cgtaggttac
     7381 aactcccgtg accttgttct cagtttttgt acggcttaag gttacaggtt gaacaacatc
     7441 ttcttttaca ttttggttcg taactttatc aacgtaatga atgatacgcg ttatagtctt
     7501 cgtctcagta gaggttgctg ttttgggaac cactgtttcc tcaacattct cacggtagta
     7561 atagtcaact gttgcaccgt cttctggtac gcatttgcag gagttgctac caaggtgtat
     7621 gttgttttcc ttgtgataac tcggtcttct ttgtcctcag ttgttgtttt cccttcaata
     7681 gtttttgatt ctgtggtata ctcagaacct atcgctaaat cagcttttat aacagactct
     7741 gccaacttct cttggctacc ttctttatag taattggctg ttactgtagc agtggttggc
     7801 gcttcgcttt ctctataaac taaggtcact gttctacctt cgcttacaat attcccagtt
     7861 aaacttgcag aatttgtatc tgcttcttta aaa
//
LOCUS       DAVBEM010000072         7474 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVBEM010000072 DAVBEM010000000
VERSION     DAVBEM010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7474
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.072"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            60..929
                     /locus_tag="VQ548_001958"
     CDS             60..929
                     /locus_tag="VQ548_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET2654751.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            933..1889
                     /locus_tag="VQ548_001959"
     CDS             933..1889
                     /locus_tag="VQ548_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET2654752.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKLPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            1889..2653
                     /locus_tag="VQ548_001960"
     CDS             1889..2653
                     /locus_tag="VQ548_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2654753.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            2653..3363
                     /locus_tag="VQ548_001961"
     CDS             2653..3363
                     /locus_tag="VQ548_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2654754.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKIPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            3828..4484
                     /locus_tag="VQ548_001962"
     CDS             3828..4484
                     /locus_tag="VQ548_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2654755.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDESIDLPALREKFEANGIQVEEIARTSAKVL
                     "
     gene            4592..5687
                     /gene="prfB"
                     /locus_tag="VQ548_001963"
     CDS             join(4592..4663,4665..5687)
                     /gene="prfB"
                     /locus_tag="VQ548_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HET2654756.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            5705..6397
                     /gene="ftsE"
                     /locus_tag="VQ548_001964"
     CDS             5705..6397
                     /gene="ftsE"
                     /locus_tag="VQ548_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HET2654757.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            6390..7316
                     /locus_tag="VQ548_001965"
     CDS             6390..7316
                     /locus_tag="VQ548_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2654758.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
BASE COUNT         2208 a         1292 c         1682 g         2292 t
ORIGIN      
        1 agaacctatc aaaaagtgag ggaaaaccct cggaattata aatagaaaga gtgaatctta
       61 tgctccaaca actcgtaaat ggtttgattc taggtagtgt ttacgcgctg ttagccctag
      121 gatataccat ggtttacgga attatcaagc tcatcaactt cgcccatggt gatatttata
      181 tgatgggagc ctttatcggt tatttcttga tcaattcttt ccaaatgaat ttctttgtag
      241 cgcttattgt agctatgcta gcgacagcta ttcttggtgt cgtgattgag tttcttgctt
      301 accgaccttt gcgccactct actcgtattg ctgttttgat tacggctatt ggggtttctt
      361 tcctattgga gtatggaatg gtctatctgg ttggtgccaa tacccgtgcc ttccctcaag
      421 cgattcaaac agttcgatat gatttgggac caattagctt aacaaatgtg cagttaatga
      481 ttttggccat ttccttgatt ttgatgattt tgttacaagt cattgtccaa aagactaaga
      541 tggggaaagc catgcgtgca gtatcagtag atagcgacgc ggcgcaattg atggggatca
      601 atgtaaaccg tacgattagc tttaccttcg ctttgggttc tgctcttgcg ggtgcggctg
      661 gtgttctgat tgctctttat tataactctc ttgagccttt gatgggggtt actccaggtc
      721 ttaaatcttt cgttgccgca gtacttggtg gtatcggaat tattcctggt gcggctcttg
      781 gtggctttgt gattggtcta ttggaaacct ttgcgactgc ctttgggatg tcagatttcc
      841 gtgatgccat tgtttatgga atcttgttgt tgatcttgat tgtccgccca gctggtatcc
      901 ttggtaagaa tgtgaaagag aaggtgtaaa cgatgaagga aaatttaaaa gttaatattc
      961 tatggttact ccttttgtta gctggctata gcttgattag tgtactggtt tcagtcggag
     1021 tacttaatct attctatgta cagattttac aacaaattgg aattaatatt attttggctg
     1081 ttggtctcaa cttaatcgtt ggtttttcag gacaattttc acttggtcat gctggtttca
     1141 tggcgattgg tgcctatgca gcagctatta ttggttctaa attaccaacc tacggtgcct
     1201 tctttggagc tatgcttgta ggggctttgc tttcaggagc agttgcctta cttgtcggca
     1261 ttccaacctt gcgcttgaag ggggactatc ttgcggtagc aactctaggt gtttctgaaa
     1321 ttatccgtat ctttatcatc aatggtggaa gtcttacaaa tggtgcggca ggtatcttag
     1381 ggattcctaa ctttacaact tggcaaatgg tttacttctt tgtcgtgatt acaaccattg
     1441 caaccttgaa cttcttgcgt agcccaattg gccgttcaac cctctctgtt cgtgaagatg
     1501 aaatcgctgc tgagtcagtt ggggttaata cgactaaaat taaaatcatc gcttttgtct
     1561 ttggtgccat tactgcaagt attgctgggt cacttcaggc aggatttatc gggtctgttg
     1621 taccgaaaga ttacaccttc attaactcaa tcaacgtttt gattattgtt gtatttggtg
     1681 gactcggttc cattacaggt gcgattgttt cggctattgt tctgggaatt ttgaatatgc
     1741 ttctccaaga tgttgctagt gtgcgtatga ttatttacgc tttagccttg gtattggtaa
     1801 tgattttcag accaggtgga ctccttggaa cgtgggaact gagcctatca cgtttcttta
     1861 aaaaatctaa gaaggaggaa caaaactaat ggcattactt gaagtaaaac agttaaccaa
     1921 acattttggt ggtctaacag ctgttggaga tgtgactctt gaattgaacg aaggggaact
     1981 ggttggatta atcggtccaa acggagctgg gaaaaccacc cttttcaacc ttttgaccgg
     2041 tgtttatgaa ccaagcgagg gaacagtaac cctagatggt caccttttga atgggaaatc
     2101 accttataag attgcctctt tgggacttgg acgtactttc caaaatatcc gtctctttaa
     2161 agatttaaca gttttagata atgttttgat tgcttttgga aaccatcaca aacagcatgt
     2221 ttttactagt ttcttacgct taccagcttt ttacaagagt gaaaaagaat taaaggctaa
     2281 agctttggaa ttgttgaaaa tctttgattt agatggtgat gcagagactc ttgctaaaaa
     2341 tctttcctac ggacaacaac gtcgtttgga aattgttcgt gcccttgcta cggaacctaa
     2401 aattctcttc ttagatgaac cagcagcagg tatgaaccca caggaaacag ccgaattgac
     2461 tgagttaatt cgtcgtatca aagatgaatt taagattaca atcatgttga ttgaacacga
     2521 tatgaatctg gtcatggaag taacagaacg tatctacgta cttgaatatg gccgtttaat
     2581 tgctcaagga actccagacg aaattaagac caataaacgc gttatcgaag cttatctagg
     2641 aggtgaagcc taatgtctat gttaaaagtt gaaaatcttt ctgtgcatta cggtatgatc
     2701 caagcagtcc gtgatgtaag ctttgaagtt aatgaaggag aagttgtttc ccttatcggt
     2761 gccaacggtg caggtaagac aactattctt cgcaccttgt caggtttggt tcgaccaagt
     2821 tcaggaaaga ttgaattttt aggtcaagaa atccaaaaaa taccagctca gaaaatcgtg
     2881 gcaggtggtc tttcacaagt tccagaagga cgccacgtct ttcctggctt gactgttatg
     2941 gaaaatcttg aaatgggagc tttcttaaag aaaaatcgtg aagaaaatca agctaacttg
     3001 aagaaggttt tctcacgctt tcctcgtctt gaagaacgta agaaccaaga tgcagctact
     3061 ctttcaggag gggaacaaca aatgcttgcc atgggacgcg ctcttatgtc aacaccaaaa
     3121 cttcttcttt tagatgaacc atcaatggga cttgccccaa tcttcatcca agagattttt
     3181 gatatcattc aagatattca gaagcaagga acaaccgtcc tcttgattga acaaaatgcc
     3241 aataaagcac ttgcaatctc tgaccgagga tatgtattgg aaacaggaaa aatcgtccta
     3301 tcaggaacag gaaaagaact cgcttcatca gaagaagtca gaaaagcata tctaggtggc
     3361 taaaacaatc cagtggattg ttttagtcgg cagatgaaga ttacgaagta atcatcaata
     3421 tagtccgggg gcccttttta gtcggtagat tgagattgcg aagcaatcat caaatccaga
     3481 ggattgtttt agccggcaga taaagattac gaagtaatca tcaatatagt ccgggggccc
     3541 tttttagtcg gtggatgaag attgcgaagc aatcatcaaa tccagaggat tgttttagcc
     3601 ggtagattga gattgcaaac aaatctgcat ctacattgaa agcttaattt ctaataattg
     3661 aaaaaatcga atgaaaagtt tcttaccttc attcacagag ctcgatttta gagctctttt
     3721 tgctagctta ttcatacttt tctaaatttt gaaaaagaaa tgtaagcgtt tgatagattt
     3781 gcaaaaagat tgtataatag ggataagaat agaaaaggag aagtctcatg gcagttaaag
     3841 attttatgac ccgcaaggta gtttatatta gtccagatac aacagtatct catgcagcag
     3901 atttgatgag agagcaaggt ttgcaccgtc tgcctgttat cgaaaatgat caattggttg
     3961 gtttggtgac tgagggaacc attgcacaag caagtccatc taaagcaaca agtctttcta
     4021 tctatgagat gaattatctt ctgaataaga caaaagtaaa agatgtcatg attcgcgatg
     4081 ttgtcactgt ctcaggctat gctagtctag aagatgcaac ttatctgatg ttgaaaaata
     4141 agattggtat tctccctgtc gtagataacc atcaagtata cggagttatt actgaccgtg
     4201 acgttttcca agcctttctt gaaattgcag gttatggcga agaagggatt cgtgtacgct
     4261 ttgttacaga agatgaagtt ggtgttcttg gaaaaattgt ttctttgatt gtagaagaaa
     4321 atttgaatat ctcccataca gtcaatattc cgcgtaagga tggtaaggtg attatcgaag
     4381 tgcaaatcga tgaatcaatt gatttaccag ccttgagaga aaaatttgaa gcaaatggta
     4441 ttcaagtgga agaaatcgct cgcacttcag caaaagtctt gtaagaaggg aagtccaaag
     4501 gcttcttttt tcatgaaaag gggattagag caaaagatgg aaagaaatga taaaatatgc
     4561 tataatgaaa taatgtaaaa aaggagtatt tatggacatt tcagtaattc gtcagaaaat
     4621 tgacgcaaat cgtgaaaaat tagcttcttt cagggggtct ctttgacctc gaagggctag
     4681 aggaagagat tgccatcttg gaaaacaaga tgacagaacc tgatttttgg aacgataata
     4741 ttgcggccca aaaaacgtcg caagaattga atgaattaaa aaacacttac aataccttcc
     4801 ataagatgga agagttgcag gatgaagtcg aaattttatt ggattttttg gctgaagacg
     4861 agtcagtgca tgatgaactg gtagcgcagt tagccgaact tgataagata atgaccagct
     4921 acgagatgac tctactcttg tcagaacctt atgaccacaa caatgccatc ttggaaatcc
     4981 atccaggttc tggtggtact gaggcgcagg actggggtga tatgttgctt cgtatgtata
     5041 ctcgttatgg taatgctaaa ggctttaaag tggaagtgtt ggattaccaa gcaggtgatg
     5101 aggctggtat taagtcggta actttatcat ttgaagggcc taatgcctat ggtctcctca
     5161 agtcagaaat gggtgttcac cgcttagtgc gaatctcacc atttgactct gccaaacgtc
     5221 gccatacctc tttcacatct gtagaagtga tgccagaatt ggatgatact attgaagtgg
     5281 aaatccgtga agatgatatc aagatggata ccttccgttc aggtggtgcc ggtggacaaa
     5341 acgtcaataa ggtttcaaca ggtgtacgtt taacccacat tccaactgga attgttgtcc
     5401 aatcaacagt ggatcgtacc cagtatggaa atagagatcg tgccatgaag atgttgcagg
     5461 ctaagctcta tcaaatggag caagataaga aggctgcgga ggtagattct ctcaaaggtg
     5521 agaaaaagga gatcacttgg ggaagccaaa tccgttctta tgtcttcacg ccttatacta
     5581 tggtaaaaga tcaccgaact agctttgagg ttgctcaggt agataaggtt atggatgggg
     5641 acctagatgg ttttatagat gcttatctca agtggcgaat tagctaagat agaaaggaac
     5701 tcacatgtca attattgaaa tgagagatgt cgttaaaaaa tacgacaacg gaacgactgc
     5761 tctacgcggt gtttcggtca gcgttcaacc gggggaattt gcttacatcg taggaccttc
     5821 aggagcaggg aagtcaactt ttattcgttc tctgtatcgt gaagtaaaaa tcgataaagg
     5881 aagtctatca gttgctggtt ttaatctggt taagatcaaa aagaaagatg tcccgcttct
     5941 acgtcgtagt gttggggttg tcttccaaga ttataaattg ttaccaaaga aaactgtcta
     6001 tgaaaatatt gcttacgcta tggaagtaat cggggaaaat cgccgtaata tcaaaagacg
     6061 agtgatggaa gttttggact tggttggatt gaagcataag gttcgttctt tcccaaatga
     6121 actctcaggt ggggagcagc agcgaattgc gattgcgcgt gcaattgtaa ataatcccaa
     6181 agtattgata gctgatgagc caacaggaaa tctggatccg gataattcat gggaaattat
     6241 gaatctcttg gaacggatta acctacaagg gacaactatt ttgatggcga ctcataatag
     6301 ccagattgta aataccttgc gccaccgtgt cattgccatt gaaaatggcc gtgtcgttcg
     6361 tgacgaatca aaaggagagt atggatacga tgattagtag attttttcgc catttatttg
     6421 aagccttaaa aagtttgaaa cgaaatggtt ggatgacagt agctgctgtc agttcagtca
     6481 tgattacttt gaccttggtg gcaatatttg catctgttat tttcaataca gcgaaactag
     6541 ctacagatat tgaaaataat gtccgtgtag tagtttatat ccgaaaggat gtggaagata
     6601 atagtcagac aattgaaaaa gaaggtcaaa ctgttacaaa taatgactac cacaaggtat
     6661 atgattcttt gaagaacatg tctacggtta aaagtgttac cttttcaagt aaagaagaac
     6721 aatatgaaaa attaaccgag ataatgggag ataactggaa aatctttgaa ggagatgcca
     6781 atcctctcta tgatgcctat attgtagagg caaacactcc aaatgatgta aaaactatag
     6841 ccgaagatgc taaaaaaatt gaaggtgtct ctgaggttca agatggcggt gccaatacag
     6901 aaagactctt caagttagct tcatttatcc gtgtttgggg actagggatt gctgctttgt
     6961 taatttttat cgcagttttc ttgatttcaa ataccattcg tattaccatt atttcccgca
     7021 gtcgcgaaat tcaaatcatg cgcttggttg gagctaaaaa cagttatatc cgtggaccgt
     7081 tcttgttaga aggagccttt atcggtttat tgggagctat cgcaccatct gttttggtct
     7141 ttattgttta tcaaattgtt taccaatctg tcaacaaatc gttggtaggg caaaatctat
     7201 ccatgattag tccagattta tttagtccgt tgatgattgc cctactattt gtgattgggg
     7261 ttttcattgg ttcattggga tcaggaatat ccatgcgccg attcttgaag atttaggtaa
     7321 aatagctgct tttatgagga gattgtaaaa tctccttttt tgctacaaga gtttttgaaa
     7381 agagatgcgt agaagaaaag agcttccaaa gaagtccccc agagaagact tcttgatggc
     7441 taatttgaac ttgaaatttg gcgcactaga aatt
//
LOCUS       DAVBEM010000073         7220 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVBEM010000073 DAVBEM010000000
VERSION     DAVBEM010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7220
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.073"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            231..645
                     /locus_tag="VQ548_001966"
                     /pseudo
     CDS             231..645
                     /locus_tag="VQ548_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(684..1127)
                     /locus_tag="VQ548_001967"
     CDS             complement(684..1127)
                     /locus_tag="VQ548_001967"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HET2654759.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(1157..3379)
                     /locus_tag="VQ548_001968"
     CDS             complement(1157..3379)
                     /locus_tag="VQ548_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HET2654760.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            3790..4032
                     /locus_tag="VQ548_001969"
     CDS             3790..4032
                     /locus_tag="VQ548_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654761.1"
                     /translation="MTRFEEIFEEYKNPQDTFFYPLVYKENTYEKTAISIFALLMLGV
                     CCLFLFSQQSYKKLVQYYANDQNLPSRITYSEYSDK"
     gene            4372..5001
                     /locus_tag="VQ548_001970"
     CDS             4372..5001
                     /locus_tag="VQ548_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET2654762.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(5124..7016)
                     /gene="pepO"
                     /locus_tag="VQ548_001971"
     CDS             complement(5124..7016)
                     /gene="pepO"
                     /locus_tag="VQ548_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HET2654763.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
BASE COUNT         1985 a         1681 c         1378 g         2176 t
ORIGIN      
        1 ttatcatttt atgacaaaca tactatcgtt aaatgctgat ttaatcgaaa ttttgagtta
       61 taaactcctc agtttcgaac tcaaaattag ccgtgcagga taggataccc ttcataaact
      121 tatataacta ctttaatacc ttaaaaagct aataaaataa ggaatatcta agcaatatac
      181 attctaaaat acctgtacgg gagtgtctct aaagaaaagg aggttttagc atgaaaaaaa
      241 tcatcttcat caaaaccatt caactccttg tcattgatgg aatcatgctg gcatttttga
      301 catttaaaag gggggcttac ttgggactgg attttgattt atagtggttg gctcattttc
      361 tttcatcctg tgctattgac ctatctttca aaccaacttt gtgaccactt tagtcaactc
      421 tattcccaga ttagaccgag attctggcgt tttgctttac aaattctcct atgggatagc
      481 ctgatgattc tctccttggt gtctttaagt gatattccac ttttccttca gggaactctc
      541 ctcatcctag gacatctcat cccttcctat cgcatctgcc aaagcctgaa aagagacttc
      601 ccccaagcat atcaagaacc gatttctttt tggagtattt tatgatcgat gagaaagacc
      661 aagccgactg ggcttggtct ttcttatctc tttttagtat ctaggataat ggtaacaggt
      721 ccgttattaa ccagctcaac ctgcatatct gctccaaaga tacctgtctg aacgggcact
      781 tcttgcgcta atttttgatt gaaagcatca tagaagtctg atgccatatc aggtttagct
      841 gcccctgtaa aggctggacg attgcctttc ttagtatccg caaagagggt aaactgagaa
      901 atagagagga tttctccttc aatatctttg acagacaggt tcatcttgcc ttctgcgtct
      961 gaaaaaatcc gcatattgac cagttttctc acagcatagt ccaaatcttc ctcttggtcc
     1021 tctggtccaa caccaaccag caataaaagt ccctgattga tttttccctg aatctggcct
     1081 tctatactca cttgggcttt tttaacccgt tggataatga ttttcataat agcctttcta
     1141 gtaagagcta ggacaactag ccgttggtcc gtttgacaga gtaaacttct ggcacactct
     1201 taattttatc gacaaccgtg gtcagtgtag agaggttggc aataccgaag gacacatgga
     1261 tattagcaaa cttcatatcc ttggttggtt gggcattgac cgttgaaata ttcttggttg
     1321 tatttgaaag aacttgcagt acatcgttca acagtcctgt acggttgaga ccgtagatat
     1381 cgatatgggc catatactcc ttatttgagc tagagtactg gtcttcccat tccacatcaa
     1441 ggagacgttg ctcgtagttt tcttgggcac gcaggttcat acagtccaca cggtgaatag
     1501 ccacaccacg acccttggta atgtagccaa caatatcgtc accaggcacg gggttacaac
     1561 acttagcaat ccgcactagg agaccagaag caccttcaat aaccactccc ccctcatgct
     1621 tgaccttgag agtttcttta ttttcaacct tgacctcgcc acctttgaca agctcctctg
     1681 cctcagcctt ggccttggca cgctcttcct cacggcgttc cttttcagtc agacggttaa
     1741 agacggtaat cgcaccgatt tccccaaaac caatggccgc aaagagggag tcttctgtct
     1801 tgtaactggt cttttgcaga acttgatcca tgtggcgctt gtccataaat ttatttgcca
     1861 catagccatt ttcttggaac tgagccatca gcatctcacg acccttgttg acagacaatt
     1921 ccttatcttg gtttttaaag aactggcgaa tcttattgcg cgccttgcta gtcttgacca
     1981 tattgagcca gtcacggcta ggtccaaagg agttcgggtt ggcgataatt tcaacctgat
     2041 cccctgtctt taacttggtt gtcagtggaa ccatgcggcc attgaccttg gcaccagttg
     2101 ctttttcacc gaccttggta tggatttcgt aggcaaaatc aatcggtcct gaatctttgg
     2161 gaagagaacg gacagctcca tctggggtaa aaacgtaaat ctcctcagcc agatagtttt
     2221 ccttaacaga gtccacaaat tccttagcat catcagcctg gtcttggagc tccatcatct
     2281 ccttgatcca gttcattcca atagctgatt ccttgctgtt aacttgcccc tttatacctt
     2341 tcttataagc ccagtgagcc gcaaccccgt actcagccac ctcgtgcatt tccttggttc
     2401 gaatctggaa ttcaatcggc ccttttggtc cataaacagt cgtatggata gactgataac
     2461 cattagcctt gcggttggca atatagtctt tgaagcgacc tggcatcggt ttccaaaatt
     2521 catgcacgta accaagcatg gcataaacat cactttgggt atctaaaata caacgaatag
     2581 caatcagatc atagatttcc tcaaaccgtt ttctcttgtc ctgcattttg cggaaaattg
     2641 agtaaatatg cttgggacga ccataaatct tccctttcaa gtgacgttct gtcgtatact
     2701 cctctaattt tgtgactacc tcatccacca aggcctcacg ctccctgcgc ttttccttca
     2761 tcatatgggt aatcttgtaa aactccgttg gattgagata acggaaagac aagtcttcta
     2821 attcccattt gacactggaa atccccaaac gatgggcaag cggggcatag atttccatgg
     2881 tttctttgga aatacgctcc tgcttgtctt ttcgaagatg tttcagggtc cgcatattgt
     2941 gcaagcggtc agacagtttg accaaaataa cgcggatgtc ctcagacatg gccatgagca
     3001 tcttgcgatg attttccgct aattgctcct cgatcgattt gtactcgacc ttgccaagct
     3061 tggtaactcc gtcaacaatc atccgcacat caggaccaaa ctctctttcc aaatcgtcca
     3121 aagtcgcatc tgtatcttcc accacatcat gcaagaatcc acaagctact gttacagcat
     3181 ccagctttag cttagctaaa atacctgcca cttggatagg gtgaatgata taaggctcgc
     3241 ctgatttgcg atattgacca ctgtggcatt caacagcata gaccaaggcc ttatggacaa
     3301 aatgaacatc ctcttccgtt aaatattctt tggttaaagc gacaacttct tcgcctgtta
     3361 aattcacttc tttcggcatc tctactctcc aattcttcct accattttat cactttttta
     3421 agaatatgaa aactagattg gaacagaata agaaaaaaat aattcaaaat tgcttgataa
     3481 ttctgaatta ttggcccata atatactacg aagttagatt ttaaacttag gtgatagaag
     3541 gagagataga agaacggaaa ccatattgta acccaaagac tttctgattt ccccaattcc
     3601 attgaagata cgaaagataa acggtggaac tcgtatcaca tacactggta ccttgactgg
     3661 attttggaat taatactcaa tgaaaatcaa agagcaaact aggaaactag ccacaggttg
     3721 ctcaaagcac tgctttgagg ttgtagataa gactgacaaa gtcagtcaca tatatacggc
     3781 aaggcgacgt tgacgcggtt tgaagagatt tttgaagagt ataaaaatcc tcaagatact
     3841 ttcttctatc ctttagttta taaggagaat acctatgaaa aaactgctat ttctatcttt
     3901 gctctcctaa tgttaggagt ttgctgcctg ttcctattca gccagcaaag ctataaaaaa
     3961 ctcgttcaat actatgctaa cgaccagaac ctgcccagta ggataactta tagtgaatat
     4021 agcgacaaat gagaagccaa ctacggtagc actctaaaca tcacgtctat caaacaagct
     4081 aatgacggag tttatgcaac ctatgaaggg caattgacac ctttccaata ttgataaatt
     4141 gataaccagc ctgtcttcat ctagtcatgc tggtttttaa gttcatttta aatccttacc
     4201 tattctccct aactgtgcta tacttaattt atactcaatg aaaatcaaag agcaaactag
     4261 aaagctagcc gcaggctgtt caaagcactg ctttgaggtt gcagataaag ttgacgcggt
     4321 ttgaagagat tttcgaagag tattagtaca ttctttgaga ttggagttag tatgaaaatc
     4381 cataaaaccg tgaatcctgt tgcctatgaa aatacctatt atctagaagg cgaaaagcac
     4441 ctcatcgtcg tcgatcctgg tagtcattgg gaagccattc gtcagacaat cgagaagatc
     4501 aacaaaccga tctgtgctat tctcttgacc cacgcccatt atgaccatat catgagtctg
     4561 gacttggttc gcgagacgtt tggcaatcct cctgtctata tcgcagagag cgaagccagc
     4621 tggctctaca ctcctgtcga taatctctcc ggtctccctc gccacgatga tatggcagat
     4681 gtggtcacaa aacctgcaga acacaccttt gtctttcacg aagaatacca actagaggaa
     4741 tttcgtttta aggttctacc gaccccaggg cactctatcg gtggtgtttc cctagtcttt
     4801 cctgatgctc acctagtctt gacgggagat gctctattcc gcgaaactat cggacggacc
     4861 gaccttccga ctggtagcat ggagcaactc cttcatagta tccagaccca actcttcacc
     4921 ctaccaaact acgatgtcta tccaggacat ggtccagcta ctactatcgc tcacgaaaag
     4981 gccttcaatc cctttttcta gcaagatgat gacaatcgaa atttaagtaa actatccagc
     5041 aaatctttct attacaaaag gcatcctatc aaggttttca cacgtgattg gatgcctttt
     5101 ttctgatgac tagatttttt gtattaccaa ataatcacgc gctcctctgg tgaacgccac
     5161 attccgtctc cttctttgac atcataggtt gtaaagaaat cgtcgaagtt tggtacttgc
     5221 acattgacac ggagtttggc tggtgcgtgc acatcgacgc tagccaaaag tttcataaat
     5281 tctggtcgac ctttcatgcg ccagatgcga ccgaagttgt agaagaactc ttctgctgag
     5341 aagtctgctt ctctcttagc tgcttcaagc gctgctgcga ttcctcccaa gtcagccacg
     5401 ttttctgata cagtcaattt accgttaatg gttgctccat aagaatcctg tccatcaaat
     5461 tggtcaatga ctttttgtgt tttctccttg aaggcagcat agtcgctctc tgtccaccaa
     5521 tccttgaggc taccattttc gtcaaaggaa gccccgttag tatcaaaggc gtgggaaatt
     5581 tcatgggcaa tcactgcccc aataccaccg tagttagcag aagatgactg atgcaagtca
     5641 tagaaaggcg cctgtaaaat ggccgctgga aagacaatca ggttcttctg aggattgtag
     5701 taggcattga ccatatgagc aggcatgccc cattccttat agtctacagg ctggttccac
     5761 ttactccaac tgtgcttgat ttccacacgc gcaaaggcta gagcattctc aaaaagactg
     5821 gcagtttcat tcactacctt atccttgtaa cgtgcaggca attcttctgg atagccaata
     5881 taaggtttga tcacattgag cttcacgata gcctgtttac aggtttctgg agtgagccag
     5941 tcattcttaa gcagacgctc cttatagaca tcaatcatgg ttgccacttt tttctccaca
     6001 tccgccttgg cttctggaga gaacttctca cgggcgtacc aaagccccag ggcttgcttg
     6061 aaaggttcct gtgctagatg ataagctgct ttgaccttat cttttgcctc tggaactcca
     6121 gaaagggcac ggctgtaggc accagacaaa acacggatat cctctgttaa atagctggtt
     6181 gaaagattga caacactcaa aatcaaggtt gctttaagga gagaccaggc ttcctcactg
     6241 taaaattgct ctgctgcttg ccagaaacgt tcctcgtcta caataacctt gtctggtaat
     6301 tgcccaataa ctgctttgaa gaagtcatcc aaaggtaggg caggcgcgaa tttcttgaaa
     6361 tcttcgtaag aatatggatg atagagttta gcatattctg aactttcttc attagagagc
     6421 accactgccg caactcggcg gtccaattca agtctttttt ctagcaagtc ttcaatttct
     6481 tcatcagaga aatcataagc cttgaggaga tttgcgctgc tttctttcca aagagtcaag
     6541 agctcttcgc gctgaggatg ttcttctgca tagtaggtcg tatctggcaa gattgtgctt
     6601 ggagcgctag cccatagaac attgattcta gcatccataa agtctggcga tacaccaaaa
     6661 ggaaggaagt ttggttttcc tgcaagctca aactctgcta gtttagctgt aaaatccgca
     6721 aaagtttcca attcttggaa ttctttaagg agtggtaaga caggtgtgat accgtcagct
     6781 tctctcttgt caaaatcacg aactaggcgg tggtatttga caaagttttc caagatagca
     6841 tcctcaggca cttcttcacc tgctaaccac ttgtctgttg tcgccagcat caggtcttca
     6901 atttcctggt ctaaatcaac aaaacctcct gtttgagact tatctgctgg gatttcagct
     6961 gtctgttgcc attctccatt gatagcatca taaaaatcat cttgataacg tgtcatcttg
     7021 ttctcgcttt catttgtatt tgcatttatc ttaacaaaaa tcactaggga atgcaattaa
     7081 taaccattta actattattt tttagctatt ataaaaaacc tttccatgat aaaacgcata
     7141 attccaagtt ttttacactt gatactatgc gttttataat ttagaaattt atcctgaaag
     7201 ttatctttag aatctatttt
//
LOCUS       DAVBEM010000074         7162 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVBEM010000074 DAVBEM010000000
VERSION     DAVBEM010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7162
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.074"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(741..1001)
                     /locus_tag="VQ548_001972"
     CDS             complement(741..1001)
                     /locus_tag="VQ548_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654764.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADIHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
     gene            complement(1060..1611)
                     /locus_tag="VQ548_001973"
     CDS             complement(1060..1611)
                     /locus_tag="VQ548_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654765.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIYEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(1601..1798)
                     /locus_tag="VQ548_001974"
     CDS             complement(1601..1798)
                     /locus_tag="VQ548_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654766.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(1802..2386)
                     /locus_tag="VQ548_001975"
     CDS             complement(1802..2386)
                     /locus_tag="VQ548_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654767.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEIPKELTPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(2794..3219)
                     /locus_tag="VQ548_001976"
     CDS             complement(2794..3219)
                     /locus_tag="VQ548_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654768.1"
                     /translation="MTSRVFIDADCISAFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNYDSNKIIGKGEATSIFLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(3212..3706)
                     /locus_tag="VQ548_001977"
     CDS             complement(3212..3706)
                     /locus_tag="VQ548_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654769.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMVLGHYIKSTEQLLENNRISQGKYEELLLDAFRYDIVYGLDEEGE
                     LSFD"
     gene            complement(3752..3958)
                     /locus_tag="VQ548_001978"
     CDS             complement(3752..3958)
                     /locus_tag="VQ548_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654770.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            complement(3945..4106)
                     /locus_tag="VQ548_001979"
     CDS             complement(3945..4106)
                     /locus_tag="VQ548_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2654771.1"
                     /translation="MNMINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(4471..5427)
                     /gene="lytA"
                     /locus_tag="VQ548_001980"
     CDS             complement(4471..5427)
                     /gene="lytA"
                     /locus_tag="VQ548_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HET2654772.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPDFTVEPEGLITVK"
     gene            complement(5803..7155)
                     /locus_tag="VQ548_001981"
     CDS             complement(5803..7155)
                     /locus_tag="VQ548_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET2654773.1"
                     /translation="MDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVGRFLGQE
                     SLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWILGALLSI
                     LVMLLGFLGLYHLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLRSIGDSL
                     AALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRKSVPELL
                     PQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQTAARRI
                     MTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIFLFFASP
                     ALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPLVSSFIE
                     LIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAILATKVQS
                     "
BASE COUNT         2298 a         1486 c         1132 g         2246 t
ORIGIN      
        1 tggtttcgca ggaagtctat tatatatgca cagacatatg aaatcttttt gagacagcag
       61 ttatgatata tttatccatt cacaacatct tctgtactaa tactacaata ttggtacatt
      121 ttgattacac aatcgtttca aaaaatatga tggaagcctg agtattttat agtaattccc
      181 ttcctatcaa ctagatcaac cagttgagtg ttgaatgttg aaacacccta gcctcagcaa
      241 aggactatga tcagcatttc ctagccaata ggacgctcca aatcacctat tctaagtcca
      301 tcactagctt ggtcagtaag atacagactg caaggcgaga ctgacgtggt tgatgagatt
      361 ttggaagagt attacaatca tagattcacc agtagacttg accgcagatt taactatagt
      421 agattgaaac tagaatagta catctctgct tctaaaacat tgttagaaat cgatttgact
      481 gtcctgatca atttgtcctg ttctcgtttc atttcactat actaaaaaac cacctgaaac
      541 aaatcaagtg actagaggat aaaaacaaag actaggcaaa aagttttgaa aagcaaaaaa
      601 cgcataatat caggtcttga aaaaccttga tactatacgt ttgattgtgg gaagattgac
      661 ttcattttct cctgaaattg aagttttttc tagtttccag atatagacga attcaatata
      721 gccatctcgc tacaattatt ttaaccatcg agaaaatttt tcagaatttc aaaaatttca
      781 ttttgatcca atgaaatgtc atcattttga agaatagttg acttcacagg ctctaattct
      841 atcacaaagc ggtgtatgtc tgcttttacc gcactacttg atgttatagc cgataacttt
      901 tcatctccta gcaaggaagc tgtcaaacgg gtaaggtcat tcaaatgctt tttaatggac
      961 ttacttaaac cttgagcacc tgtagcagag cgttccctca tatccagcca agctttagcc
     1021 ttaaaaataa ttaatactca atgaaaatca aagagcaaac taggaagcta gctgcaggct
     1081 gctcaaaaca ctgttttgag gttgtagatg gaagctgacg tggtttgaag agattttcga
     1141 agagtataaa ccacaattac tcaataccga atacccctga atggtttctt tttcatgcac
     1201 caatatatta taataatctt catccaataa taaggctgat aaactagcat cttggtcaaa
     1261 atgtaaggga atttctcgac cgtccttctt taatggatat tctggtaaga tactaaatag
     1321 ttcaatcata gaaggaaact caggattagt tgttgtaaat cgaaaaagct gcgctttctc
     1381 atctttctga cttccttgat actctcccaa ttctaaaaaa tgattcaagg tagtataaaa
     1441 ttccttattt tttacttcat aaatgatgac catatcataa tcttttgttg tgcgactttt
     1501 aaatccttgc gaatccaata cgatagaggt agcagttccc ccaatcagaa cataatagtt
     1561 ctgaaaatcc gcaaacattt cttgaaaaat aactttcgta ttagctggca tcatcttctc
     1621 ccagatactg taatatcata ttttctagtg cttcactctc ttcctctata cgtgggtcat
     1681 catcatcttt taaggtcaaa taaagagaaa tcggatctac aaattgttta tcatgattat
     1741 ttttaaaatc attccaaaac tcagatacaa aaggacgata tttccatatc tctagcatct
     1801 ttcattttaa aacatgctga gaaagtggca aggataactg attgaatttt ctctgccata
     1861 tgacatagct agtattttca tccgtttcag ctaaaaaagt tgaatgcgac aaagcataag
     1921 caccaccata tagaaggtta gaaacagatt ttatctgctt tatatcgcca tctggcaata
     1981 aaaaggcaat ccacgttaat tgttcgctag gtgttaattc cttagggatt tcagtatcat
     2041 tcgcattgag tactagtccc aatggaggga agaagaggtt tcccttaaag tctacaaacg
     2101 gaactctagc ttgaagtaat tgcttttttt cactgtctga taacttcgaa aacaccaaaa
     2161 caacatccat attggctttt tcacccatag tgcgagcctg agtaacaaat gaactcaaac
     2221 tcccccttct cttttcttta atcaataaaa atgattcctt atgaaaagtc atttgagtat
     2281 actcaaacct ttttacaaaa ctgattggta aagtcaaagt cagttcctca atactgacat
     2341 caacataaaa ggattgaaaa attgacatta tctttttgac attcatgttt tttccttatt
     2401 ctatcatttt tattatattt tatcattcgg tataataaaa tataagtttt ttgataaaat
     2461 aaccaaaaac tactcgctat cccctctcac attaccctac atatcgtttg acatgcgact
     2521 gatagttcag gaaaacttca aggagaactt ttctctcatc cactatgcag gacttactat
     2581 ttcacttcta ctcctatagg ctcaatttga cacttttctt tttcgaattg ctcatatgcc
     2641 tcctgaatag tgagttcgat ttatccaaat ttatttttgt ctattttgat gaatacttcc
     2701 acgaagatag tctgaaaatg aatttgcacc aattttcctt ctctttttaa gcatattatt
     2761 ccagatatga ttgccctctt gttcagtaat aaattacgct ttaaacgctt caatcagtat
     2821 atctcctgtt gtcatatgtt ctaaagaaaa ttcttctaca tatggtttaa catctcttag
     2881 gttattactt cctaatatcc cattatgctt tttcgctaag aaaatagaag tcgcttctcc
     2941 cttaccaata atcttgttac tatcataatt tcttgttaaa tctctatata atgcgtattc
     3001 ttcagttcca atgtctatgc tcacaatctc agctgaaccc ttagttacca actggtctat
     3061 cctagatttt aaatggggaa ttgtaggtat attgatttca tcatacacct cttgtggaat
     3121 aacaatttta cccgaataga gcttttctaa aagatgttca gtgccaaccc ataaaaatgc
     3181 tgaaatacaa tctgcatcaa taaatacacg actagtcaaa cgacaactcc ccctcttcat
     3241 ctagcccata tacaatatca tatctgaaag catctagtaa cagttcctca tacttccctt
     3301 gcgaaattct gttattttct aaaagttgtt cagtcgattt aatatagtgc cctaatacca
     3361 tttccttttt actttctgac aaaggacgat ataaacttgt atcatagcct aatcttgaag
     3421 ctgtctctat aacactaata tccatatttt taatttcttc tgcatcaagg tatccatcat
     3481 ttctcaatct atataacata gctttatgac tgataccata aaactgaccc aattttataa
     3541 tatcttctac ttcaagatga gttctattgg cattttctct gatttcctca accatcctat
     3601 acagtgaaga tgggaaaatt aaaaaataag aagcaaactg atccgctttt ctttcagttt
     3661 catctccttc accaatcaag ataagactga ctgaactctt cttcacctca tcataataaa
     3721 gatgatacag tccatgtgct aaagaaaatc tttaccttcc taatggcatg tctgaattga
     3781 ctgcaatgag actgaactga gttcctttat aacagactcc gctaatattc tttccgagtc
     3841 cataaaatac cagcgtcaaa ttttctatct tttgtaccaa tttaaaaata tctatcggcg
     3901 attcaccatc agctcccaac ttttttctaa gatttgaagc tttattactt aaatccattc
     3961 gtgatattcc tttcaccttt ttccattttg gcaatcatgc tttgattcaa agacaaatac
     4021 tcagcaatct tatcttgagt aagatttgaa gatattctaa gttcttttat tctttttcca
     4081 acatcacata catttatcat attcatacac ctctcataaa aagaatagca cattcttgtc
     4141 ataatttttt aaataaaaaa attatgacaa aacaaggaag caatttattg atgctactta
     4201 aaaatctaaa attgatgata ttaaacctat ttgatgagtt cctatcaaaa atcgtatctt
     4261 caacctcaaa acagtactta aagctatccg actcggttta cattgtcaaa tttagatttt
     4321 atttgagcat aactttctag tttgcttttt gatttttgtt taatatagta acaaaaattg
     4381 aaggaaatat ctccacaaga aaacgcatac tattaagctt tttcaagacc taataatatg
     4441 cgctgttctg atttgaaaga cattccatta ttattttact gtaatcaagc cttcaggctc
     4501 tactgtgaag tctggcttgt ctgccagtgt tccgtctggt ttgaggtagt accagcctgt
     4561 tccgtccgct gactggataa aggcatttga taccatggcg ccttctttag cgtctaagta
     4621 gtaccaagtg tccttgtact tgacccagcc tgtcttcatg gcaccttctt cgttgaaata
     4681 gtaccactta tcagcgattt tcttccagcc tgtagccatt tcgcctgagt tgtcgaacca
     4741 gtaccagttg ccgtctgtgt gcttcctcca gcggtctgca agcatatagc ctgaactgtc
     4801 aaagtagtac caagtgccat tgattttctc aaacttgtct tttggataag agccgtctga
     4861 atgtacgtac cagtagccag tgtcattctt ctgccagcct gtttcaatcg tcaagccgtt
     4921 ctcaatatca tgcttaaact gctcacggct aatgccccat ttagcaagat atggataagg
     4981 gtcaacgtgg tctgagtggt tgtttggttg gttattcgtg caatactcgt gcgttttaat
     5041 tccagctaaa ctccctgtat caagcgtttt cggcaaacct gcttcatctg ctagattgcg
     5101 taagagttcg atataaaggc ggtagtccgt catgaactct tctttggttg aatggctttc
     5161 aatcagttca accgctgcat aggtctcagc attccaaccg cccccaacgt cccaggcacc
     5221 attatcaaca ggtcctacct gcatgatgca accgttccca acaatgtgcg agaaaaaacc
     5281 taattctggg tctttccgcc agtgataatc cgcttcattc tgtacggttg aatgcggatt
     5341 cccagttgag tgtgcgtgta cttgcctata tggttgcacg ccgacttgag gcaaatctgt
     5401 tcttaattta ctcacattaa tttccatatt ctactcctta tcaattaaaa caactcattt
     5461 tttacaatcc agaaccagaa actcctttat ttctacctta caaagaagac aatcttagtc
     5521 acgattaagc ttgtagatag aacctcaaaa cgcactattt tgacactgta aataggactg
     5581 acaaggtctg cattctatct acaataacac cccagactaa aaagcttttc aaaagtatat
     5641 ttttacagtc tctatatgtc cttttcataa atactatact ttattatatc acataaaaga
     5701 agtcaaaagt ctgttaaact attttcaaca ccaaactaaa gaagagaaca caagtttttt
     5761 cgatgttcac tagaggaaat ggattttatt cagtaaatcc aactaggatt gcactttggt
     5821 tgccaaaatt gcctttcctt cttttatcaa gggatgacgg aatagtgaga agtacagttg
     5881 aactgtcatg gcaacccaga taagaggttc acaaaggata acacccttat atcctgccca
     5941 aggaataatc aaaaccacaa aaacgatttt tccgattagt tcaataaagc tagaaactag
     6001 aggaaggatc ttctgcccca agccctgcaa gcaattgcga taaatcaaca agaggctcaa
     6061 aatgggataa aaggctgaac tgatttgcag atagagactt ccattttcta tcaagtaacc
     6121 atctgtcgaa ctagccaaga aggaaaccaa ggctggactg gcaaaaaaga ggaaaataca
     6181 aacaaaaact gcccaggata tacttaaacg actgccgatt cgaagacctt gaacaatgcg
     6241 gtcaggtcgc ttagctccta gattctgaga agcaaaggtc gtcattgatg cagaaatagc
     6301 ggtcatagga agaagggcaa aggtcataat gcgtcgagct gccgtctggg cactaataat
     6361 cactgcacca aatgtattaa cagaaaactg taaaatcaca ctgccgatag atacaattga
     6421 actcatcaag cccatagcca aaccttgctc caagagatcc gcgtacaagc ttttgtccca
     6481 tttgaaatgt ttaaactgtg gcaagagttc tggcacactt ttacgaatat aataaaagca
     6541 gagaaccgct gataaacctt gcgaaataat ggtagcaagt cctgcggatt gaactcccag
     6601 atgcaattgc gtaataaaat agagatccag aaccacatta accaaggcag agaaaatcag
     6661 aaatcccagg gctgctagac tgtcaccaat agaccgcaac aagcctgcaa aaagattata
     6721 agcaaagctg acacctacac aggtcacaat catagaaata tattgataag attgaggaag
     6781 aatttctgca ggagtatcta agtattgcaa gagatgatac aagccaagaa agcccagcaa
     6841 cataactaga atgctcaaaa gagcacctaa aatccaagta gctgctactg cttccttgat
     6901 tttagtgaaa ttccgagccc cataataacg agcaatgaca atccccatgc cattgccaac
     6961 accaagtgta aaacctacaa tcaggtcaaa aatcgctgtc gtcgctccta ctgcagccaa
     7021 ggattcttga ccaagaaatc gtccaacaat caagacatca gcagtgttat agagctgttg
     7081 aaaaatattt gatagcaaaa ttggaaaggt gaagcttaag agcgagggaa gaatcggacc
     7141 atgtatcagg tccactgttc gt
//
LOCUS       DAVBEM010000075         6834 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVBEM010000075 DAVBEM010000000
VERSION     DAVBEM010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6834
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.075"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(201..1625)
                     /locus_tag="VQ548_001982"
     CDS             complement(201..1625)
                     /locus_tag="VQ548_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HET2654774.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMLKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2169..4448)
                     /gene="pulA"
                     /locus_tag="VQ548_001983"
     CDS             complement(2169..4448)
                     /gene="pulA"
                     /locus_tag="VQ548_001983"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HET2654775.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4560..6518)
                     /gene="ligA"
                     /locus_tag="VQ548_001984"
     CDS             complement(4560..6518)
                     /gene="ligA"
                     /locus_tag="VQ548_001984"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HET2654776.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6611..>6834)
                     /locus_tag="VQ548_001985"
     CDS             complement(6611..>6834)
                     /locus_tag="VQ548_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2654777.1"
                     /translation="FFTQVQTKVESEFLGRVLSTIFTLAILFMPIAKGFMTVLPSVHL
                     SSFLIIGSGVIILSCISFIYVRTHFEKLI"
BASE COUNT         2022 a         1502 c         1239 g         2071 t
ORIGIN      
        1 actatatata gtaaaatgaa ataataacag gacaaatcga tcaggacagt caaatcgatt
       61 tctaacaatg ttttagaagt aaatctgtac tattctagtt tcaatatact ataataccaa
      121 aaagttcgta ttttttctat aattattatt attttatagc aaaaaataaa accaggaaaa
      181 caatttcctg attttacacg ttatttcaca tcaaaaacaa tggatttgac atttgtcatc
      241 gcttcaatgc tatatttaat tccttgcact ccagctccag aacctttgac accaaggaat
      301 gggaaattat ctggaccacg ctgggtttta ttattaatgt ggactgtacc tacttcaagt
      361 ttttcagcaa tttcaaaggc ttttttgaaa tcatttgtaa agactgatga ttgaaggccg
      421 aattcagatt cgttggcaaa ggcaatagct tcctctacac tagccacacg aatgattggt
      481 aaaacaggac caaatggctc ttcccatgcc actttcatat cttttgtaac ttggtcaaaa
      541 agcactggcc agaggagatt gccctcacgt ttgattggtg taagagcctg agcctctttt
      601 tcttgtgcat cctcaatcaa gccccaaatg aagtcggctg aagcattgtc aataacaggt
      661 gtaatatcag cattgtcaaa tggatcacca actgttaatt tagaaacttc ttcctgaagc
      721 aaagtagcta atttatctgc tacactttcg agaacaatga cacgtttaat ggccgtgcaa
      781 cgttgtcctg agtagctaaa ggctcccgca acaatttgct tggcagcatg ttccaaatct
      841 gcatcttcta gtacaagagc tgcatctttc ccaccaagtt ccaacatgat aggacgcata
      901 ccagctaaac gaccaatacg ttctccaata ggagttgaac ctgtaaagtt gatgaagttg
      961 acttctttgt gctcaatgat ataatcccca atttctgaac cacgacctgt aatggtgttg
     1021 aaaacacctg ccggaatccc tgcttcttca aatgctttag ccaacaagag tccagaaatg
     1081 gaaccttgtg ttggtggctt caacatgacc acattccctg caatcaaggc aggtgcaatt
     1141 ttagaagcag ataaattaac tggataatta aagggagcaa tcgctagcac gataccaact
     1201 ggttcacgac ggacaacagc cagtttgttt ttacttgctg cctcaaaacc accaccttcc
     1261 attgcttgtc cagtgatacg gagaccttcc tcagcagcat aacgaatcaa gtctgctgta
     1321 cgcactactt ctccaattgc tgctttaatc ccttttgcta cttctttggc aaggatagta
     1381 ccaatttttt ccttatcgcg ttctaaaata gctgctgttt tatgcaaata agccgcacgt
     1441 tcaattgctg ataaagctcg ccatgctggc agggctgcac gcgcagcttg catagcctca
     1501 tcagcttcag tctgagtcat ggctggaact gtacccaatt cttcttgatt gattggtgaa
     1561 taaatcgtaa tttcttgttc agatgatttc cattttccat ttactaaatt ctgatatctt
     1621 gtcaaattct tgtcctcctg aaaatgatta agatatattt taccaaattt tcagaaaata
     1681 acaacccttt ttgcaaaatt tttgagatta ttttcacaag cttgattttt caaagtatac
     1741 tcaataaaaa taaaaaaatc cactacgtca aggcgaggct aatgtggttt gaagaaattt
     1801 tcgaagagcg tgaatgagta tcatctatag taaaataaaa aaactgaaca atttggttgg
     1861 ggacagccaa accaatttct cacaatgttt cagaaacaag ggtgtgctat tccaatttca
     1921 gcctactata actgtcatag attgctgaaa caaagtctag gtaaaagtct tcataataaa
     1981 aagacctcct atcaaatgtt caaaaacttt gataggaggt cttgtttcgt gaaaatattt
     2041 atcaaatttt ctatacaagt gagctgttag ccaggttctt tctattcttt caatttcaat
     2101 gaatggattt tttaccaata ctcataactg ggaatttttc tgtctaaaaa tagcgagata
     2161 gatggtattt ataaaacact caagacagct agactaatat catttaaaac attatcttct
     2221 tttgagcgac tgttggttac caacatagct aaatttcctg cattttcaaa ttgatagggt
     2281 tctgatttag cattcacaac taccaagagg tgttctttgc cgtgaacttc atagataagg
     2341 cagccgctat gttcaatcgc agaatgcaca aagacatgat ggtaaatttc atcatagcta
     2401 gagtaagaaa aggcaccagt ttttgtcttc aatcggatga cttgacggat aaactcaata
     2461 ctgtcttgac gctcattaat caagttccag ttcacttggt tcacactgtc aggagcatta
     2521 tagctattca tcgcacgctc tctatcatca tgggtcaact caccattttc accagtcgca
     2581 accagtttgg tacgaccaaa ttcttgaccg atttccataa aggccatccc ctgcatgagc
     2641 agattcatgg ctgtggcagt ttcgaccttg cgcatgattt gctctgaact ttggtctgga
     2701 tgaagggttg ccaataaatc gtgaagattg taattgtcat gggcttctac atagttaagc
     2761 acctgatttg gatgtgtata gcttcctaat tcacgacttc ctaggattgc tttagctaga
     2821 attggctctg tcgcagcacc actgacaaaa cctgacttga tagcaccata aacttctccc
     2881 cctttgacag catcgcgctg attgtcatta aagaaaccaa tatttggcat ctggtaggca
     2941 ttgtccttct tggccttatc ataaggggca agacctgttc ccatatccca tccttctcca
     3001 tagaggataa tgttggagtc aatttcatcc aagctttgac gaatcatctg catggtcttg
     3061 acatcatgaa tccccatcaa gtcaaaacgg aagccgtcaa tattatattc ctgcacccag
     3121 tatagaagag aatcaatcat atacttgcga aacatttcgt gttcactggc tgtttcattt
     3181 ccaacacccg ttccattctg gaaggtacca tctggattca tacgataata gtaatcaggg
     3241 actgttgttt ggaatggtgc atcaacaact gagaaggtat ggttatagac tacatccata
     3301 atgactccaa tacccgcatc gtgataagct tgaaccatca ccttcaaatc acgaatgacc
     3361 tgagctggat catctggatt agttgaaaaa ctagtttctg gcgcgttata gttttgtgga
     3421 tcataacccc agttgtaggt tacatttcca tcctcatcgt attctttatg acggtctgca
     3481 attggttgca attgaacata attgtagccc agcttcttga tgtaatcaaa agcagttgac
     3541 tggccgtatt ggttaactgt tccagcctga gcagcaccca agaaagttcc tcgaagatgt
     3601 tcatctacac ccgatgtagg tgatttagtc aaatcacgaa tatgcatttc acagataact
     3661 gccttacatg gattttccaa gcgccaagta gcctccgaac cgtgcttaac ctcgaagttt
     3721 tcaacttgct tttctacatg gctcagaata gctgaacgtt tgccatcagg gctggtcgcg
     3781 attgtataag gatcacgtgt cagtgtttgg tgatgaggga attggacttg atactgataa
     3841 gtcttaccta ccaaatcttc ttcaacatcc aaactccaga caccgattgt attgtcctta
     3901 tgattataag agtagctatt gcctcttttc atctcaaaag tcttccaaac gggtgcatca
     3961 ttagcagctg attcataaac gacaacttgc acttctgtcg ctgtaggtga ccagagggaa
     4021 aaatgagcct gattgtcctc tacacggcaa cccaattctc cttggtaacc ccaatgatga
     4081 tcaaaactag cactgttaat ggccttatca aaggcaaaag gattttgatt tttatagaaa
     4141 ggactggcaa tagcaggatt ttcagagtaa taaatcctat catcgccttc caaaatccag
     4201 acctctgtta ataggggata gtgattaaaa cggatagaat attctttact agtttgacct
     4261 gtatgaacca caaaattcaa gctttctata acatgtgaac ttgggtgttc aaagctaaat
     4321 aaagctccaa aataatcttc tttgtaggtt agcaaatcaa ttcgttgatc ctgacttttt
     4381 acaaaggagc aagtgtcata ttctccattc ttacgatggt aatgaatgcg catagggtag
     4441 ttatacattt tttatttttc ctttttactt tgtttctatt tcactaataa atttttgtca
     4501 atctcgtctc aattaacaga catagtcata ttctctaaac tctgttttta aacgatccat
     4561 tacaaacttt ctagccatgc ctcatctctg acctggatac caagttcttg tgctttttgc
     4621 agtttacttc cagcgtctgc acctaccacg acgaggtcgg tctttttaga aacactacct
     4681 gtcactttgg cacccagact ttcgagttta cttttagctt ctgagcgctt gagtcgttcc
     4741 aattttcctg tcaataccac ggtcaaacct gacaaggccg catccgctac taccgtctgt
     4801 cctttatagt ccagattgac cccagtttct ttcaattctc tgagcagaat ttcagagcct
     4861 tctgtcgcaa aataagtctg aagacttttg gcaatcacgc cacctagact ttcaatacta
     4921 gccacttcct ctgaatctgc ctgagacaga ttttcaattg aatggaaata ttgaagtaaa
     4981 agctgactag ccttgcttcc gacatgacga attcccaaac caaataagag cttctcggca
     5041 gaattttcct ttgatgcttg gatagcctga tacagtttag cagcggactt ttccttaacc
     5101 ccctctaaaa ggaggaaatc ctcttcttgc aaacgataaa tatccgccac atccttgact
     5161 aaattagcag caaaaagctt ctcaacaata gatggaccaa ggcctgtaat attcatagca
     5221 tcacgagaag caaagtgaat caagccttcc atgatttgag cagggcaacg cggattgata
     5281 caacgtaggg ccacttcatc ttcaaagtgc aacaagtcag agttacaact tggacagttt
     5341 gtagggatat ctagtttttc ttcagaaacc cgtttggact ctaccacacg taaaacggca
     5401 gggatgatgt caccagcctt atatacaatg accgtatcgt cttttcggat atctttttca
     5461 gcaatataat ctacattgtg cagggtcgca cggctaacag tcgtaccggc aagttgtact
     5521 ggtgttagat tagcagttgg agttacaaca ccggtacggc caactgtcca gtcaactgat
     5581 aagagttgag cttctttttc ttcagcaggg aacttgtagg ctactgccca ctttggagcc
     5641 ttaacggtaa aaccaagttc ttcttgactt gctaggtcgt tgaccttgat taccactcca
     5701 tcaatatcgt aaggcagatt ttcccgttcc tgtcctactt cttggataaa attccagatt
     5761 tcatctatgt tttcagccaa gattcgctta ggattgacca caaaacctag ttgttctagg
     5821 tacttcaaac ccttttcttg gctatcacga gttgaagggc tggcttcttg atagagaaac
     5881 gttgcaagat tacgcttggc aactactgct gtatccaact gacgcagagt tcctgctgcc
     5941 gcattacgag gattagcaaa ttcaggctct ccattttctt ggcgcacttg gttaacttgg
     6001 tcaaaggaag cgcgtggcat gtaacattcc ccacgaactg tgatatctag ttcttctggc
     6061 aaagtcaaag ggatgtcctt aacacgcttg aggttttctg tgatattttc accaattgaa
     6121 ccatctccac gtgttacccc agcaaccaaa atcccctttt cataagtcag cgagatagat
     6181 aagccatcga ttttcagctc acaaatatag gtcggatgag ccacttcctt acgaacacgc
     6241 gcatcaaaag catctagctc ctcacgtgaa aaagcatcct gcaaactata aagaggatac
     6301 tgatgactgt atttttcaaa accatctaaa accttgccac caacacgatg agtcggactg
     6361 tctgctagca cttgctctgg ataagcagtt tctaactcga ccaactcacg gtaaaggcgg
     6421 tcatactcac tgtctgaaac cgagggatta tcgctggtat agtactcagt cgcatagcga
     6481 ttgagcaaag cgactaactc attcattctt ttattcataa gaccatttta ccataaaaca
     6541 agccctcctc acaaacgaga agggcggaaa aaacacttag tttgaaatta tttttgaaac
     6601 tcaagcaacc ttatatcaat ttttcaaaat gagttcgaac ataaataaac gatatacaag
     6661 acaagatgat aacaccactt ccaattatca ggaaagaaga gagatgtaca cttggcaaga
     6721 ctgtcataaa tccttttgca ataggcataa atagaatagc taaggtaaaa attgtactca
     6781 gtactcttcc aagaaattcg ctctcaacct tggtttgtac ttgagtaaaa aagt
//
LOCUS       DAVBEM010000076         6728 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVBEM010000076 DAVBEM010000000
VERSION     DAVBEM010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6728
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.076"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            <1..155
                     /locus_tag="VQ548_001986"
     CDS             <1..155
                     /locus_tag="VQ548_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2654778.1"
                     /translation="FGHKLLPLPPYSPEYNPIEKTWVHIKKHLKKVLPSCNTFYEALL
                     SCSCFN"
     gene            216..1178
                     /locus_tag="VQ548_001987"
     CDS             216..1178
                     /locus_tag="VQ548_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET2654779.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYDDTSISVSSNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVIIFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVEPLRYE"
     gene            1355..2362
                     /gene="gap"
                     /locus_tag="VQ548_001988"
     CDS             1355..2362
                     /gene="gap"
                     /locus_tag="VQ548_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HET2654780.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2429..3265)
                     /locus_tag="VQ548_001989"
     CDS             complement(2429..3265)
                     /locus_tag="VQ548_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2654781.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQYLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETYVSRLKQFSNKTSLARCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            3391..5586
                     /locus_tag="VQ548_001990"
     CDS             3391..5586
                     /locus_tag="VQ548_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET2654782.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMASQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVAAVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIAYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5639..5791
                     /gene="rpmG"
                     /locus_tag="VQ548_001991"
     CDS             5639..5791
                     /gene="rpmG"
                     /locus_tag="VQ548_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2654783.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5801..5977
                     /gene="secE"
                     /locus_tag="VQ548_001992"
     CDS             5801..5977
                     /gene="secE"
                     /locus_tag="VQ548_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HET2654784.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6033..6569
                     /gene="nusG"
                     /locus_tag="VQ548_001993"
     CDS             6033..6569
                     /gene="nusG"
                     /locus_tag="VQ548_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HET2654785.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2092 a         1172 c         1461 g         2003 t
ORIGIN      
        1 agtttgggca taaactttta cctcttcctc cctactcacc tgagtacaat cctattgaga
       61 aaacatgggt tcatatcaaa aagcacctca aaaaggtatt accaagttgc aatacctttt
      121 acgaggctct tttgtcttgt tcttgtttca attgactata tatcacggat acagttggga
      181 aagaagctat taaacatttg gagagtcctt ttgggatgaa catgtcaaat attactatag
      241 atgggcaaga aatggatctg agtcaaacga tgccttctta tgctcaagta gtgagtcttt
      301 atgatgatac aagtatctct gttagtagta atgagacgga caaagtgttg gctggctccc
      361 tctatactga tacaaatgaa cagggattaa cgattccaag cagtttacta aaaaattgga
      421 atgaacagac aggaaaaaat ttgacagcta atgatcttat tggcaaatca gtctcagcca
      481 gcattgtaga aagtgctgcc gaaactagta agattgctca atttcaaacg aagattgtac
      541 gtgtaatcaa tgatgaagat gacatggagg acagcaacag tttcatgctg tctcatcaaa
      601 tggaaacgat tttgaaagag gctggattta cgaaagctgt atcttatttt atcttggaac
      661 tcaaagatcc atcacagaca aaagtagtaa cagaagaatt acagaaaaat aagaagtata
      721 ctgtgctttc tcaacagaga gttcttgata ttgtgattat ctttattcgt gttattcagg
      781 gattattgat tgtgctttca tcacaagcta ttgtggtagc agcggttatg attggtatca
      841 ttatttacat caatatcatg cagcgttcca aggaaatagg tgtcatgaag gcagttggtt
      901 atcagaatcg tgatgtcaaa ggaattttta tttacgaggc tatctggatt gtaggcatcg
      961 ccttgctgct ggcatttttg gttgcacaag gggtgggaag tttggcgaat gcgattgtaa
     1021 gtcactttta cccatccatc actaaagttt ttgaattaaa tcttttatct gttttaggaa
     1081 ctctagtttt cgctctatta cttggttatg tctcagccta cttcccggcg cgtaagatta
     1141 gtaaaatgga tcctgtagaa ccgttacgct atgaatagta agggattcct tgatttacag
     1201 tcttaaaaag aaactaacat agaaaaacaa tggacatact tgcaattcaa ctcaaatagt
     1261 tgtataatag gtttgttgaa aggtgatttg tagtgattca agttactctt ttcacaataa
     1321 aaatttcatg attttcataa ggaggaaatc actaatggta gttaaagttg gtattaacgg
     1381 tttcggacgt atcggtcgtc ttgctttccg tcgtatccaa aacgtagaag gtgttgaagt
     1441 tacacgcatc aacgacctta cagatccagt tatgcttgca cacttgttga aatacgacac
     1501 aactcaaggt cgtttcgacg gtactgttga agttaaagaa ggtggatttg aagttaacgg
     1561 taaattcatc aaagtttctg ctgaacgtga tccagaacaa atcgactggg ctactgacgg
     1621 tgtagaaatc gttcttgaag ctactggttt ctttgctaag aaagaagcag ctgaaaaaca
     1681 ccttaaaggt ggagctaaaa aagttgttat cactgctcct ggtggaaacg acgttaaaac
     1741 agttgtattc aatactaacc acgacgttct tgacggtact gaaacagtta tctcaggtgc
     1801 ttcatgtact acaaactgct tggctccaat ggctaaagct cttcaagaca actttggtgt
     1861 tgttgaagga ttgatgacta ctatccacgc ttacactggt gaccaaatga tccttgacgg
     1921 accacaccgt ggtggtgacc ttcgccgtgc tcgcgctggt gctgcaaaca tcgttcctaa
     1981 ctcaactggt gctgcaaaag ctatcggtct tgtaatccca gaattgaatg gtaaacttga
     2041 tggatctgca caacgcgttc caactccaac tggatcagtt actgaattgg tagcagttct
     2101 tgaaaagaac gttactgttg atgaagtgaa cgcagctatg aaagcagctt caaacgaatc
     2161 atacggttac acagaagatc caatcgtatc ttcagatatc gtaggtatgt cttacggttc
     2221 attgtttgac gcaactcaaa ctaaagttct tgacgttgac ggtaaacaat tggttaaagt
     2281 tgtatcatgg tacgacaacg aaatgtcata cactgcacaa cttgttcgta ctcttgaata
     2341 cttcgcaaaa attgctaaat aattcttgag ttgatagaaa gcaaggcttt gtggtcttgc
     2401 tttttatatg gaaaaatgga tgacacgatc atccattctt ttttaattct ttttcaaatg
     2461 tatttgaaag ggtagtgaaa gttagcttct ctaaagtaag tgggtgggta aaggaaagtc
     2521 ggaaggcatg aagcataagc cgacttgtct ttgatttact attatagaga gggtcgccca
     2581 ggataggaag attatgatgc gaaaggtgca cacgaatctg atgggttcgc cctgtcttta
     2641 gcttgcaacg agccaaggaa gtcttgtttg agaattgctt taatctgctt acatacgttt
     2701 cagcatattg cccatttttt gcatcaacta ttctttttct acgatcatgg cgatcacgtc
     2761 caattttgtc tctgaaaaca agttcttttc tgttgatatt tccatcaact agagcccaat
     2821 attctctaga aatctctttt ttctccaata agcgattgag aatgggcagg ataaaaggat
     2881 ttttggcaaa gagaactaag ccactggttt ccatgtccag acgatgaacg acatagcagg
     2941 tttggccaac ataggtactg acatggttaa gaagggcaat ttcgtttggt tgattaccat
     3001 gcgttttcat cccctctggt ttgtttacaa taatcaagta ttgatcttga taaacttcct
     3061 gcactaagtc tgggttgccc caagggatcg tcttttgggg ataatcttcc tcgtcaaaag
     3121 tcaactggca aacatctcca ggatttacga tttcgttcca gtggacttct tcttgattta
     3181 tcaaaatatg tttcttgatt ctcaaaaaat gacggatttt tctagggatg aggagttgtt
     3241 cctcaagtaa ttgctttacc gtcatttgag gtagagaggc gggtaatgta aatgtgaatt
     3301 gcatacagat attgtaacaa aaaaagccct atttggatag gaaatagcta aattcttgtc
     3361 ttcctatgat gaagatgata aaataaacgc atgaaattag ataaattatt tgagaaattt
     3421 ctttctcttt ttaaaaaaga aacaagtgaa ctagaggact ctgattctac tatcttacgt
     3481 cgctctcgta gtgatcgaaa aaaattagcc caagtaggtc cgattcgaaa attctggcgt
     3541 cgttatcatc taacaaagat tatccttata ctaggtttga gtgcaggctt gctagttgga
     3601 atctatttgt ttgctgtagc caagtcgacc aatgtcaatg atttgcaaaa tgccttgaaa
     3661 actcggactc ttatttttga ccgtgaagaa aaagaggctg gtgccttgtc tggtcaaaag
     3721 ggaacctatg ttgagctgac tgatatcagt aaaaacttgc agaatgctgt tattgcgaca
     3781 gaagaccgtt ctttctataa aaatgacggg attaactatg gccgtttctt cttggctatt
     3841 gtcactgctg gacgttcagg tggtggctct accattaccc aacagctggc taaaaacgcc
     3901 tatttatcac aggatcaaac tgttgagaga aaagcgaaag aatttttcct tgccttagaa
     3961 ttaagcaaaa aatatagtaa ggagcaaatt ctaaccatgt accttaacaa cgcttatttt
     4021 ggaaatggtg tgtggggtgt agaagatgcg agtaagaaat actttggagt ttctgcatca
     4081 gaagtgagtc tggatcaagc tgcgactctg gcagggatgc tcaaggggcc ggaactgtat
     4141 aatcccttga attccgtaga agattctact aatcggcgcg atactgtctt gcagaatatg
     4201 gttgcagcag gatatattga taaaaaccaa gaaaccgaag ctgctgaagt tgatatggct
     4261 tcgcaattgc acgataagta tgaaggaaaa atctcagatt accgttaccc ctcttatttt
     4321 gatgcggtgg ttaatgaagc tgtttccaag tataatctaa cagaggaaga gattgtcaat
     4381 aatggctacc gcatttacac agagctggac caaaactacc aagcaaatat gcagattgtt
     4441 tatgaaaaca catcgctatt tccgagggca gaggatggaa cgtttgctca atcaggaagt
     4501 gtagctctcg aaccgaaaac agggggagtt cgtggagttg tcggtcaagt tgctgacaat
     4561 gataaaactg gattccggaa tttcaactat gcaacccaat caaagcgtag tcctggttct
     4621 acaattaagc ctttagttgt ttatacgcca gcagttgaag caggctgggc tttgaataag
     4681 cagttggata accataccat gcagtatgac agctataagg ttgataacta tgcagggatc
     4741 aaaacgagtc gagaagttcc tatgtatcaa gccttggcag aatcgcttaa tctacctgct
     4801 gttgccgctg ttaatgattt gggtgtcgac aaggcttttg aggcaggcga aaaattcgga
     4861 ctcaacatgg aaaaggtcga ccgtgttctt ggtgtcgcct tgggaagcgg tgttgaaacc
     4921 aaccctcttc aaatggctca agcatacgct gcctttgcaa atgaaggttt aatgcctgaa
     4981 gctcatttta ttagtagaat tgaaaatgct agtggacaag ttattgcgag tcataaaaat
     5041 tcacaaaaac gggtgattga taagtctgta gctgacaaga tgaccagtat gatgttgggg
     5101 actttcacca acggtaccgg tattagttca tcgcctgcag actatattat ggcagggaaa
     5161 actggaacaa ctgaagcagt tttcaatccg gagtacacaa gtgaccagtg ggtaattgct
     5221 tatactccgg atgtagtgat tagccactgg cttggctttc ctaccactga tgaaaatcac
     5281 tatctagctg gctctacttc aaacggtgca gctcatgtct ttagaaacat tgccaatacc
     5341 attttacctt atacgccagg aagtaccttt acggttgaaa atgcttataa gcaaaatgga
     5401 attgcaccag ccaatacaaa aagacaagta caaaccaatg ataatagcca gacagatgat
     5461 aatttgtctg atattcgagg gcgtgcgcaa agtctagtag atgaggctag ccgggctatc
     5521 tcagatgcga agattaagga aaaggctcaa acaatatggg attcgatagt caatctattt
     5581 cgctaagatg cttgtcaaag cctagctttc ttgttataat ggataggatg gaggcgttat
     5641 ggcactaaaa aaagcaagcc tagcttgtgc ggtttgtggt tcgagaaact attcaatcaa
     5701 gatcagcgga aaccccaagc ctacacgact agaagtaaat aaattttgta agcattgtgg
     5761 caagtacact acacacagag aaacgagata ggagagagcg atgcgtttta ttggagatat
     5821 ttttagactt cttaaagaca caacgtggcc aactcgcaag gaaagctgga gagattttcg
     5881 ttctatcatg gaatacacag ctttctttgt agtaattatt tacatttttg accagttgat
     5941 tgtttcaggt ttgattcgat ttattaacat tttttagaag attagtggag ttaattacac
     6001 tagaaatctt ctatattatg aaaggaaata tcatggatag ttttgataaa gggtggtttg
     6061 ttttacaaac ttattctggt tatgaaaata aggtgaaaga aaatctatta caacgtgcac
     6121 aaacctacaa tatgttggat aatattctac gcgttgaaat tccaacacaa acagtgcaag
     6181 ttgaaaaaaa tggaaagaga aaagaagtag aagaaaatcg ctttccaggt tatgttcttg
     6241 tagaaatggt catgacagat gaagcttggt ttgttgttcg aaacacacca aatgttacag
     6301 gatttgtcgg atcacacggg aacagatcaa aaccaactcc attattggaa caagaaattc
     6361 gtgacatttt ggtatctatg ggacaaactg ttcaagaatt tgatttcgat gttgagattg
     6421 gtcaaactgt acgtattatt gatggtgctt ttgcagacta cactggtaag attacagaaa
     6481 ttgataataa caaagtgaaa atgattatct ctatgtttgg taatgacaca gttgcagaag
     6541 taaacctaaa ccaaatcgca gaattataac cctgagagag gctggagcct ctcttttttg
     6601 tgcagtttag gagctaaagg gaacagaatg gagaaaatgt aacaaatgtg ttttctaatc
     6661 tgttagactg tatctagaaa ggggaaaatt atgattaaag aattgtatga agaagtccaa
     6721 gggactgt
//
LOCUS       DAVBEM010000077         6637 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVBEM010000077 DAVBEM010000000
VERSION     DAVBEM010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6637
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.077"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(84..1244)
                     /locus_tag="VQ548_001994"
     CDS             complement(84..1244)
                     /locus_tag="VQ548_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2654786.1"
                     /translation="MKKKFALSFVALASVALLAACVEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTNMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            complement(1345..1593)
                     /locus_tag="VQ548_001995"
     CDS             complement(1345..1593)
                     /locus_tag="VQ548_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HET2654787.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            complement(1672..2262)
                     /gene="clpP"
                     /locus_tag="VQ548_001996"
     CDS             complement(1672..2262)
                     /gene="clpP"
                     /locus_tag="VQ548_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HET2654788.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            complement(2436..3065)
                     /gene="upp"
                     /locus_tag="VQ548_001997"
     CDS             complement(2436..3065)
                     /gene="upp"
                     /locus_tag="VQ548_001997"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HET2654789.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETFQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(3154..3621)
                     /locus_tag="VQ548_001998"
     CDS             complement(3154..3621)
                     /locus_tag="VQ548_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HET2654790.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            complement(3640..4197)
                     /locus_tag="VQ548_001999"
     CDS             complement(3640..4197)
                     /locus_tag="VQ548_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET2654791.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            4322..5167
                     /locus_tag="VQ548_002000"
     CDS             4322..5167
                     /locus_tag="VQ548_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2654792.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEDGGLLM
                     GYEID"
     gene            5226..6398
                     /locus_tag="VQ548_002001"
     CDS             5226..6398
                     /locus_tag="VQ548_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET2654793.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSNPI"
     gene            6449..>6637
                     /locus_tag="VQ548_002002"
     CDS             6449..>6637
                     /locus_tag="VQ548_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HET2654794.1"
                     /translation="MEHIILLRGVTPNGKNAIPKMSYLVDILTEADFQQVRTYIQSGN
                     IILESNLALEEIREQVHTL"
BASE COUNT         1894 a         1385 c         1287 g         2071 t
ORIGIN      
        1 agtttgaaga gattttcgaa gagtattaaa tatcgaaaca gggagtgagt caaaggctca
       61 ttccctattt caacattttt ctattatggt tttacaactt ctgctgcttc aactttacca
      121 ttgttcatgg tcatcatgta agcagttttg actgtgttgt ggtctgcatc gaagcttgtt
      181 tgaccagtta caccttcaaa atcttttgtt ttagcaaggt tatccttgat ttcacctgaa
      241 tttttagcac cttttgctgc gtttgctaca aggtgaactg aatcataagc caaggctgca
      301 aatgttgaag gctcttcatt gtacttagca cggtaagcgt caaggaaggc tttagcttta
      361 gctgaaactt ctacagtagt tgagaagcct gagataaagt agatgtttga tgctttttca
      421 gcagttgctt gttgtacaaa ctcctcaccg ttgaatccat caccaccaac gattggtttg
      481 tcaattccca tgccacgcgc ttggtttaca atcttaccag cctcattata gtaaccagga
      541 acaacgatag catcaaagtc tttccctttc atgtttgtaa gggctgcttg gaagtctgtg
      601 tcacctgcta cgaaagtttc atctgcaacg atttcaccct tgtatgactc gcggaaagat
      661 ttagcaatcc ctttagcata gtcactggca ttgtcagtgt aaagaacaac tttcttagca
      721 tttaattttt cagaaacata gtttgagata atttttcctt ggaagctatc ttggaaagtt
      781 ccaataaaga ggtaatcttg acctttagtc aatccatctt gagtcgcact tggtgagatc
      841 aatggaacac ctgcttttgt agcgttcgct accgcagctg cagtcgcacc agatgtcgca
      901 ggtcctacga ctgctgatac tttagattgg gttacaaggt tagttgtaac tgaagcagcc
      961 tcagctgttt cagacttatt atctttatcg actacttcga tttgttttcc atcgatacca
     1021 cctgcggcat tgatttcatc aacagccaat tgggcacctt tttgttcagc tgttccgtat
     1081 gcagctaaag aacctgattc ttcaaagtta aacccgattt taattgtctt ttcctctact
     1141 gagttaccag cagtgttgac tgctccagac ttcacttcta cacaggctgc aagaagtgct
     1201 acacttgcaa gcgccacaaa cgatagggca aattttttct tcatcttttt gtctccttat
     1261 ttcttaaata gtctgttaag aatataccga attatcagaa aattgtcaat gttttccttg
     1321 aactttttcg atgataacgt tttcctatcg ataaagattg cccacaaagg gtgtttccaa
     1381 ctcttggata tgacaaaccc taactttttt aataaatttt tccttgctca agcgtccgac
     1441 caattgctcc acttcttgag ttggaacata gagttgtaag taacgatgtt tcttggaatg
     1501 ataggtaata tctccataat cctgcagttt tttggcatca cgattatagt aaagatagat
     1561 aatcaagcca gagcgattga ctttttcaaa catgataaat cctctttcta agaaatctct
     1621 ccctattata ccaaaaaaag caaacccagt cgagtttgcc ttctatcatc attagttcaa
     1681 tgaattgttg gccataattt catcaataaa gccatattca agtgtttcct gggcgctcat
     1741 ccagttatca cgttctgcat ctgcatggac tttttccatt gactgacctg aattttcagc
     1801 caagattttt tccaaggtat tacgagtttt gagcaagtgt tctgcagcga tagccatatc
     1861 agtttgttgg gtaccaccac ctgtaccgcc cattggttgg tgaatcatgt attcagcatt
     1921 tggaagcatg aaacgtttgc cttttgctcc acttgatgcg atgactgttc ccatagatgc
     1981 agccattccc ataacaatgg tttggacatc tgccttgata aagttcatgg tatctacgat
     2041 tgccaaacca gctgaaacag aaccacctgg tgtattgaca taaaggtaaa tatcttttgt
     2101 actatcttgg gcatccaaga aaagcagttg ggcaataaca gagttagcca tattgtcttc
     2161 aaccggacct gtcagcataa tgatgcggtc tttgagaaga cgtgagtaaa tatcgtaaga
     2221 acgttctcca cggcttgttt gttcaataac tacaggaatc attcatttct ccttttgagt
     2281 tttaattttg ttggtcaaat gactgaagat aagactatta taatatcttg gtcaaaaaag
     2341 gtcaaatttt tgctctgctt tcattagaca gaaacaaaaa cccaacctcc tttcgtgact
     2401 ggaaatactt ttccaagtca ttcttctttt cgatcttatt ttgtaccgaa caagcggtct
     2461 ccagcatctc caagacctgg aacgatataa ccgtgttcgt tcaaacgttc atccaaggct
     2521 gctgtaaaga tttctacatc tggatgagct tcttgaaggg cttttacacc ctctggagca
     2581 gatacaaggc agacaaattt gatatttgat gcgccacgtt ttttaagaga atcaacagcc
     2641 aagattgctg agccacctgt tgccaacatt gggtctacta caaaaatttg acgttggtca
     2701 atgtcctcag gcaatttcac caagtattca actggttgaa atgtttcttc atcacggtac
     2761 ataccgatgt ggccaacttt agcagctgga accaagctca agagaccatc aaccatcccg
     2821 atacctgcac gcaagattgg gacgatggcc aatttcttac ctgccaattg tttttgaact
     2881 gtttttgtaa ttggtgtttc gatttccaca tcttctagtg gaagatcacg aagtacttca
     2941 taccccatca acattgcaat ctcatctact agctcacgaa aagcttttgt agaagtatct
     3001 gtacgacgca agattgacaa tttgtgttga atcagtgggt gattaataac ttcaattttt
     3061 cccatttttg gaattccttc tttcaattta ttcttcttat tataccaaaa aacgggttaa
     3121 aaatctttct aaaccattta tttttgataa tttttacatt agatcagcct ctttaagagc
     3181 tgtctgtact gtctcaagtg gtaaatgggt caattctgtc cctttttctt gataaaggta
     3241 ttgggcgtag tcgtccattc ggtactggtt gatataaacc acacgcttgc agccgacctg
     3301 aagcaattgt tttgtacagt tgagacaagg aaaatgggtt acataggctg taaagccttt
     3361 gggaacacca cgctcagcac cttgaaggat agcattgacc tcagcgtgaa gggtgcgaac
     3421 acagtggcct tcaatgacca aacattcgtg atcaatacaa tgctcagtcc ctgacaccga
     3481 accattgtaa ccagtggaaa taaccttatt atcttttacc agaatcgcgc ccactttagc
     3541 acgtttacaa gtggaacgat tcgcaattag tagagcttgg gctgcaaaat actcatccca
     3601 ggccagtctt ttttcagtca tctcttttct cctttttctc tattttttaa aaaatggtaa
     3661 acctaaatct gcaatctttt cagctggtac cttcatgcca tccttgatcc attttagaag
     3721 gacagagacg atggctgagc tccagaagga atgaagataa gagctgacac cttttgattt
     3781 cccatggtat ttttctagaa attcctgcat ggcttggaca aagatttttt ccagatggta
     3841 atccaaggcc aattgaatta ctctagcttc ctttctggcc tcccggaaaa ggtgaaccca
     3901 aaccaaataa aggtctgtct ttaaatcgta atgatgcagc tgttccataa tattgtggac
     3961 agttcgttta aagacgctct ctaaaatttc ctctttggag tcataattgc gataaaaggc
     4021 cgcacgcgaa acacctgcac gtttgaccaa ttcagaaata ctaatcttgg tcagttcctt
     4081 tttttccaag agttgcaaga gggctgtttc aatggcttct ctggttaata aattggattc
     4141 ttggtttgat tttctgagat tttcaagaga cttttcagag attctacgtt cagacataac
     4201 attttctttc tacttgtcac aacagacgga tgatgctttt gtttcaaggg ttttcatgat
     4261 ataattgtaa aaaaagacag aacctttgtc aatgtataac tgacaaagat ggagaatttc
     4321 tatgacttgg aagattattg ctgactctgg ttgtgattat cgtcaactgc caacaccagc
     4381 tattaacaca acctttgtaa gtgtcccctt aaccattcaa gtagctgatc aggtctttgt
     4441 tgatgacgcc agtctcgata ttgaccaaat gatggaaacc atgtatgcaa ctgcagaagc
     4501 ttcaaaatcg gcttgtccaa gcccagatga ctatttgcga gcatttgaag gtgccaaaaa
     4561 cattttccta gtaaccatca caggtaccct ttctggcagt cacaatagtg ctcaactagc
     4621 aaagaatatt tatctggaag accatcctga cactaagatt catgtgattg atagtttatc
     4681 tgctggtggt gaagttgacc tactcgtaga aaaattgaat gacttgattg accagggctt
     4741 gtcttttgaa gaagtggttg aagctatcac cgcctatcaa gaaaaaacta agttgctctt
     4801 tgtcctagcc aaagtcgata acttggtgaa gaacggccgt ttgagcaagc ttatcggtac
     4861 ggtcgttggc cttctcaaca ttcgtatggt cggaaaagct agtgaaactg gaactctcga
     4921 attgctacaa aaagcaaggg gatcaaagaa atcagttcaa gctgcctatg atgagttagt
     4981 aaaagctgga tatgctggtg gccgtattgt catggcccaa cgcaataacg aaaaatgttg
     5041 tcaacagctc tcagagcgaa tccgtgaaac cttcccacaa gcggatatta aaattctacc
     5101 aacctctggt ctctgcagtt tctatgcaga agatggcggt ttgctgatgg gctatgaaat
     5161 tgattaattg tattcttgac aagaggtgac catcatctct tgtttttttg tggtacaata
     5221 gagctatgaa acattttgat actattgtca tcggtggggg acctgctggt atgatggcta
     5281 cgatttccag tagcttttat ggacagaaaa ccctcctcat cgaaaaaaat cggaaacttg
     5341 gaaaaaaatt agctgggact ggtgggggac gttgcaatgt gaccaacaat ggtagcttag
     5401 acaacctgct agctggaatt cctggaaacg gacgctttct ttacagtgtt ttctcccagt
     5461 tcgataatca tgacatcatc aactttttta cagaaaatgg tgttaaactt aaggtcgaag
     5521 accacggacg cgtctttcca gccagtgaca agtctcggac tattatcgaa gctttggaaa
     5581 agaaaatcac cgaactaggt ggtcaagttg ctactcaaat agaaatcgtt tctgttaaaa
     5641 aagtagatga ccagtttgtc cttaagtcag cggatcaaac cttcacttgt gagaaactca
     5701 ttgtcacaac aggtggtaag tcttatcctt cgactggttc gactggtttt ggtcacgaga
     5761 ttgctcgcca ttttaagcat accatcaccg atcttgaggc tgctgaaagt cctttattaa
     5821 cagattttcc acataaagcc ttacaaggga tttctttgga cgatgtgacc ctaagttatg
     5881 gtaagcatgt catcactcat gatttactct ttacccactt tggtttgtca ggtcctgctg
     5941 ccctacgcat gtctagcttt gtcaaaggtg gggaggttct ctcactcgat gttttgcctc
     6001 aactttctga gaaggacttg gttacatttc tagaagaaaa tcgggaaaaa tccttgaaaa
     6061 acgctttaaa aaccttgtta ccagaacgct tggccgaatt ttttgtacaa ggatatcctg
     6121 aaaaagtcaa acaactgact gaaaaggaac gagaacaact tgtccagtcc attaaagaac
     6181 ttaaaattcc tgtaactgga aaaatgtccc ttgcaaagtc ctttgttacc aagggtggag
     6241 tcagtctcaa ggaaatcaat cctaaaaccc ttgaaagtaa gctggtacct ggcctccact
     6301 ttgcaggcga agttatggat atcaatgccc acacaggtgg ctttaacatc acttctgccc
     6361 tctgtaccgg ctgggtggcg ggatcaaatc caatctaaat atacattact aaatggaaca
     6421 atcccccaaa aaaaagaaag gaactacttt ggaacatatt atcttgctaa ggggagtcac
     6481 tcctaatgga aaaaatgcta tccctaaaat gtcttatcta gtagatatct tgacagaagc
     6541 tgattttcaa caagttcgaa cttatattca aagtggaaat attattcttg aaagtaactt
     6601 agctctcgaa gaaatacgag aacaggttca tactcta
//
LOCUS       DAVBEM010000078         6447 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVBEM010000078 DAVBEM010000000
VERSION     DAVBEM010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6447
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.078"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            222..422
                     /locus_tag="VQ548_002003"
     CDS             222..422
                     /locus_tag="VQ548_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654795.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            447..863
                     /locus_tag="VQ548_002004"
     CDS             447..863
                     /locus_tag="VQ548_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654796.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1094..1801
                     /gene="ccdA2"
                     /locus_tag="VQ548_002005"
     CDS             1094..1801
                     /gene="ccdA2"
                     /locus_tag="VQ548_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET2654797.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1812..2369
                     /gene="sdbB"
                     /locus_tag="VQ548_002006"
     CDS             1812..2369
                     /gene="sdbB"
                     /locus_tag="VQ548_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HET2654798.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2490..3881
                     /locus_tag="VQ548_002007"
     CDS             2490..3881
                     /locus_tag="VQ548_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HET2654799.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPSWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4024..4941
                     /gene="adcAII"
                     /locus_tag="VQ548_002008"
     CDS             4024..4941
                     /gene="adcAII"
                     /locus_tag="VQ548_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HET2654800.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            4949..>6447
                     /locus_tag="VQ548_002009"
     CDS             4949..>6447
                     /locus_tag="VQ548_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2654801.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLVFDPAQITYRTVNGVAVPHGDHYHFIPYSQLSPLEEKLA
                     RMIAVKGQNGAVLPGMHYLKPAPKPQVQPSTEKKQTDFAVEQVVRKVGEGYVVEIAGV
                     SHYVFAKDLAKDKIDAIENLLSKKTQETHALVAKKENVAPRDQEFYDKAYNLLTQAHK
                     VLSENKGRTSDFQALDKLAERLNNESSNKVKLVDDLLAFLAPITHPERLG"
BASE COUNT         1980 a         1172 c         1354 g         1941 t
ORIGIN      
        1 atggtttcag aaatttctct taccaacatt aaccacacca tcggttatta tagtaaaatg
       61 gaataagaac aggacaaatc gatcaggaca gtaaaatcga attctaacaa tgttttagaa
      121 gtctatatgt actattctag tttcaatata ccataactgc tcctagtcaa cctgcaagtc
      181 ctgtcccagc tccaagctca gctccgactc aagatcctag agtggtagca agcgcttcgg
      241 ctagctcaac gagcacacaa gctcaagagc aagttgacaa gtctgaactt cgtgccttga
      301 gtcaagagtt agaccaacgc ttgaaagctt tggcaacagt atctgatcca aaaatcgatg
      361 caaccaaggc tgtcctccta gatgctcaaa aagctccgga agatagtgcc ttgacagagt
      421 aaggtctgca tactgcagta gagtctgtga aggctgcctt ggactctctc aaagatgtga
      481 aagcaaatgc tagcgacagc aagcctgcac aggacaagaa ggatgcaaaa caaggaacgg
      541 aagatagtaa ggattcagat aagatgactg aaacaaactc agttccggca ggagtgattg
      601 tggtcagtct acttgccctc ctaggcgtga ttgccttctg gctgattcgc cgtaagaaag
      661 agtcagaaat ccagcaatta agcacggaat tgatcaaggt tctaggacag ctagatgcag
      721 aaaaagcgga taaaaaagtc cttgccaaag cccaaaacct tctccaagaa acccttgatt
      781 tcgtgaaaga agaaaatggc tcagcagaga cagaaactaa actagtagag gagcttaaag
      841 caatccttga caaactcaag taaaacatga tttatgaaat gtcagaccta aaagacattt
      901 tcgttcacaa aagcagtgac gagtaatcct tgtcgttgct ttttggctat tttgggggat
      961 aagatccgcc ttgactagca aaagaaaaga ttggtccaat agtgcccgat acgattttgc
     1021 gtagcagaaa gcttacaaat aaaattgaat atagtaaaat aggattagaa ttattaagaa
     1081 agttggttct ttattggaaa cgatagtatt tttaatctct gtttttctag caggtgtttt
     1141 atcctttttt tctccttgta tttttcctct tctgccagtc tatgctggga ttttattgga
     1201 tgatcaagaa agtgcaaaaa gcttttcttt gtttgggaga aaggttctct ggtcaggctt
     1261 gattcgaaca ctttgcttta tcgctggtat ctctctcatt ttctttattc taggctttgg
     1321 tgctggttac tttggtcata ttctctatgc aaattggttt cgatatgtca tgggagctat
     1381 tattatcatt ttgggtcttc accagatgga aatttttcat ttgaagaaat tagaagttca
     1441 aaaaagtttt acctttaaaa aatcagattc taatcgttat tggtcagctt ttttacttgg
     1501 tattaccttt agctttggtt ggacaccttg tattggtcca gttttaagtt ctgttttagc
     1561 acttgcggct tctggaggca atggtgcttg gcaaggagcg atttatactc tcatttacac
     1621 tctgggcatg gcccttcctt tcttggtctt ggcactagct tcaggtctag tcatgccata
     1681 ttttagtaaa atcaagcgtc atatgatgct actaaagaaa attggtggtt tcctcattgt
     1741 tttaatggga attttgttac tattaggaca agtaaatgtt ctagctggaa tttttgaata
     1801 aaggaggaca aatgaaaaaa gtaatgtttg ctggcttaag tctcttgtca ttagttgtat
     1861 tgatggcctg tggtgaggaa gaaactaaaa agactcaagc agcacaacag ccaaaacaac
     1921 aaacgactgt acaacaaatt gctgttggaa aagatgctcc agacttcaca ttgcaatcca
     1981 tggatggcaa agaagttaag ttatctgatt ttaagggtaa aaaggtttac ttgaagtttt
     2041 gggcttcatg gtgtggtcca tgcaagaaaa gtatgccaga gttgatggaa ctagcggcga
     2101 aaccagatcg tgatttcgaa attcttactg tcattgcacc aggaattcaa ggtgaaaaaa
     2161 ctgttgagca attcccacaa tggttccagg aacaaggata taaggatatc ccagttcttt
     2221 atgataccaa agcaaccacc ttccaagctt atcaaattcg aagcattcct acagaatatt
     2281 taattgatag ccaaggaaag attggaaaga ttcaatttgg tgctatcagt aatgcggatg
     2341 cagaagcagc atttaaagaa atgaactaga atcgataaaa tctgattaca agatgtagtc
     2401 agattttttt agaaaaacat tttataaata ttcacatatc tcctatattt atggtaaaat
     2461 agaattatca gtttattttg gagtcaaaga tgaatatatt tagaacaaag aatgttagtt
     2521 tagataaaac agagatgcat aggcatttga agttatggga tttgattttg ctgggtatcg
     2581 gagccatggt agggacaggc gtctttacaa tcacaggtac tgcagctgca acacttgctg
     2641 gcccagccct agtgatttca atcgttattt ctgccttgtg tgtgggatta tcagccctct
     2701 tttttgcaga atttgcctcg cgagtacccg ctacaggagg tgcctatagt tacctctatg
     2761 ctatcttagg agaattccct tcctggttgg ctggttggtt aaccatgatg gagttcatga
     2821 cagccatatc aggcgtagct tcgggttggg cagcttattt taaaggcttg ctctctcaat
     2881 acgggatagc ctttcctcag gctttaaatg gtacctttaa tcctcaagca gggacatttg
     2941 ttgatttatt gcctattctt gtcttggtct tggtgacttc gcttgtttta ctaaatgcca
     3001 aggcagcctt acgctttaat tcgattctag ttattttgaa attttccgct ttagctctct
     3061 ttgttttagt aggaatttgg aatattaagt ttgataattg gagcaatttt gctccttacg
     3121 gttttggaca aatctatgga gctagcactg gtattatggc tggtgcgtcc ttgatgttct
     3181 tcggtttttt gggatttgaa tccatctcta tggctgtaga tgaagtcaag actcctcaaa
     3241 aaaatattcc tagagggatt gtcttatcgc tttctatcgt aaccattctc tatgccttgg
     3301 tgacccttgt tttgactggt gtggttcact atagtcattt aaatgtcgat gatgccgttg
     3361 cctttgccct tcgtagtgtt gggattagtt gggcagccaa ctatgtgtca ttagtggcta
     3421 tcttgacctt gattacagtt tgtatttcga tgacctatgc cctatcgcgt atgatttaca
     3481 gtttagcacg tgacggctta gtgcctgctg cctttaagga actgacgaag actagcaaga
     3541 taccaaagaa tgctactatc ttgacaggtc tagcttcagc agtagcagca ggaatgttcc
     3601 cactagccag tattgcagcc tttttaaata tttgtacctt agcctacttg atcatgctgg
     3661 cttatggtct gattcgctta cggaaagaaa aaggaatgcc caaagctggg gaatttaaaa
     3721 caccattggt acctctgtta ccaattttat cgatcatcat ttgtttatcc ttcatgttac
     3781 agtataatat gaacacctgg attgctttcc tagttgcgtt gttagtagga agtattattt
     3841 acttcactta tggctataag cattctacca tagaagaata aagtgaaagt ctattgagtt
     3901 gttgacactc agtagatttt tatatgtgaa agaaatttca aattttttct aaaaatatct
     3961 tgacagatta aattttcagg agtagaatat ttactagtta attaaatggt taaggagttg
     4021 ttcatgaaga aacaaaattt atttttagtc ctgttaagtg tctttctttt gtgtttgggg
     4081 gcttgtggtc aaaaggaaag tcagacagga aaggggatga aaattgtgac cagtttttat
     4141 cctatctacg ctatggttaa ggaagtatct ggtgacttga atgatgttcg gatgattcag
     4201 tcaagtagtg ggattcactc ctttgaacct tcggcaaatg atatcgcagc catctatgat
     4261 gcagatgtct ttgtttacca ttctcataca ctcgaatctt gggcaggaag tctggatcca
     4321 aatctaaaaa aatccaaagt gaaggtctta gaggcttctg agggaatgac cttggaacgt
     4381 gtccctggac tagaggatgt ggaagcaggg gatggagttg atgaaaaaac gctctatgac
     4441 cctcacacat ggctagatcc tgaaaaagct ggagaagaag cccaaattat cgctgataaa
     4501 ctttcagagg tggatagtga gcataaagag acttatcaaa aaaatgcgca agcctttatc
     4561 aaaaaagctc aggaattgac taagaaattc caaccaaaat ttgaaaaagc gactcagaaa
     4621 acatttgtaa cacaacatac agccttttct tatctagcga agagatttgg gcttaatcaa
     4681 cttggtattg caggtatctc tcctgaacaa gaaccaagtc cacgacaact aacagaaatt
     4741 caggaatttg ttaagaccta taaggttaaa acgattttta cagaaagtaa cgcttcttca
     4801 aaagtagctg aaactcttgt caaatcaaca ggtgtgggtc ttaaaactct gaatccttta
     4861 gagtcagacc cacaaaatga caagacctat ttagaaaatc ttgaagaaaa tatgagtatt
     4921 ctagcagaag aattaaagtg aggaaagaat gaaaatcaat aaaaaatatc tagcaggttc
     4981 agtggcagtc cttgccctaa gtgtttgttc ctatgaactt ggtcgtcacc aagctggtca
     5041 ggttaagaaa gagtctaatc gagtttctta tatagatggt gatcaggctg gtcaaaaggc
     5101 agaaaatttg acaccagatg aagtcagtaa gagagagggg atcaacgccg aacaaattgt
     5161 tatcaagatt acggatcaag gttatgtgac ctctcatgga gaccattatc attactataa
     5221 tggcaaggtt ccttatgatg ccatcatcag tgaagaactt ctcatgaaag atccgaatta
     5281 tcagttgaag gattcagaca ttgtcaatga aatcaagggt ggctatgtga ttaaggtaga
     5341 cggaaaatac tatgtttacc ttaaagatgc agcccatgcg gacaatattc ggacaaaaga
     5401 agagattaaa cgtcagaagc aggaacgcag tcataatcac aactcaagag cagataatgc
     5461 tgttgctgca gccagagccc aaggacgtta tacaacggat gatgggtata tcttcaatgc
     5521 atctgatatc attgaggaca cgggtgatgc ttatattgtc cctcacggca atcacttcca
     5581 ctatattcct aagagtgatt tgtctgccag tgaattagct gctgcccaag cctattggaa
     5641 tgggaagcag ggatctcgtc cttcttcaag ttctagtcat aatgcaaatc cagctcaacc
     5701 aagattgtca gagaaccaca atctgactgt cactccaact tatcatcaaa atcaagggga
     5761 aaacatttca agccttttac gtgaattgta tgctaaaccc ttatcagaac gccatgtaga
     5821 atctgatggc ctagtatttg atccggcaca aataacatat cgtacagtca atggtgttgc
     5881 tgtaccgcac ggagaccatt atcactttat tccttattca caactgtcac ctttggaaga
     5941 aaaattggct cgtatgattg ctgttaaggg acaaaatggt gcagtcttgc caggaatgca
     6001 ttatttgaaa ccagcaccaa aaccgcaagt tcaaccatca actgagaaaa aacaaactga
     6061 ttttgcagta gaacaggttg ttagaaaagt tggagaaggc tatgttgtgg aaattgctgg
     6121 tgtcagtcac tatgtttttg ctaaagactt ggctaaggat aagattgatg ctattgaaaa
     6181 tctcttgtct aagaaaactc aagagacaca tgctctagtt gctaaaaaag aaaatgtcgc
     6241 tcctcgtgac caagaatttt atgataaagc ttacaatctg ttaacccagg ctcataaagt
     6301 cttgtctgaa aataaaggtc gtacttctga tttccaagcc ttagacaaat tagcagaacg
     6361 cttgaataat gaatcttcta ataaagtaaa attggtagat gatttattgg cattcctagc
     6421 accaattacc cacccagaac gccttgg
//
LOCUS       DAVBEM010000079         6187 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVBEM010000079 DAVBEM010000000
VERSION     DAVBEM010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6187)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6187)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6187
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.079"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(119..751)
                     /locus_tag="VQ548_002010"
     CDS             complement(119..751)
                     /locus_tag="VQ548_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2654802.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(773..1645)
                     /gene="sdaAA"
                     /locus_tag="VQ548_002011"
     CDS             complement(773..1645)
                     /gene="sdaAA"
                     /locus_tag="VQ548_002011"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HET2654803.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(1654..2325)
                     /gene="sdaAB"
                     /locus_tag="VQ548_002012"
     CDS             complement(1654..2325)
                     /gene="sdaAB"
                     /locus_tag="VQ548_002012"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HET2654804.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            2567..3139
                     /locus_tag="VQ548_002013"
     CDS             2567..3139
                     /locus_tag="VQ548_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET2654805.1"
                     /translation="MKSITKKIKATLAGVAALFAVFSPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(3191..4054)
                     /locus_tag="VQ548_002014"
     CDS             complement(3191..4054)
                     /locus_tag="VQ548_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2654806.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAEQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKK
                     EVEIYYQAKER"
     gene            4520..4858
                     /locus_tag="VQ548_002015"
     CDS             4520..4858
                     /locus_tag="VQ548_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HET2654807.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKINGTRITK"
     gene            4836..5195
                     /locus_tag="VQ548_002016"
     CDS             4836..5195
                     /locus_tag="VQ548_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654808.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WILPILLMAGMGDVIIN"
     gene            5214..5426
                     /locus_tag="VQ548_002017"
     CDS             5214..5426
                     /locus_tag="VQ548_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000989850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654809.1"
                     /translation="MMVVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQIK"
     gene            5841..5909
                     /locus_tag="VQ548_002018"
                     /pseudo
     CDS             5841..5909
                     /locus_tag="VQ548_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
     gene            5889..>6187
                     /locus_tag="VQ548_002019"
     CDS             5889..>6187
                     /locus_tag="VQ548_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET2654810.1"
                     /translation="MMYLDGGGVGCNWWNKRDNIAAAAVSGGMSVYQTYAIKKLIANR
                     GMMSRVVRSAITRYIGGVSMATITNALNIAATVAEVFSLGGAIAYGLDIVDGKFDG"
BASE COUNT         1901 a         1050 c         1311 g         1925 t
ORIGIN      
        1 atctacaacc ttaaaacagt gttttgagca gcccgcagct agtttcctag tttgctcttt
       61 gattttcatt gagtattact tcattttctt ctgaaataga gttgtcgccc agtctatgct
      121 attgaaaata cgccaaaact tctaagggtt tgtgagcgat ataatcaggt tgatagttta
      181 gtagatctgc ttgctctcca aatccccaag tgacggccaa tttctgaata cctgtttctc
      241 gagctcccag catatcaaac ttggtatctc cgatgatgat ggcttgttct ggtgctagtt
      301 gatgtgtctg taaggcttgg tgaatgacat ctgccttatg gggtgcttca gggctagaac
      361 cataaatacc atcaaagaaa tgatggattt ccaagttttt ggccatgtct tgagcagtag
      421 atgtattctt tgtcgtggtg atgtagagtg gataactgct cgataactcc tcaagcaagt
      481 ctataatctg aggaaagagt tgagcttcat agatgccttt tgccttatag taagaacgat
      541 atatctgcat ggcttcagaa atttggtctt tggacaggca ggtcgcaaaa ctactttcga
      601 gaggtggtcc cataaaacca cgaatagttt tggcatcagg gctaggcacc cccagctctt
      661 taaaggtata ggtaaaggca ttgtgaatcc cgatagaact atcaacgagg gttccatcca
      721 aatcgaaaaa aatcgctgtg atagaggtca tggtttctcc tatttgataa gcttattctc
      781 cgaaaatctc tttttggagg cgacgaccag taggggtggt agcgagtcca ccttcagctg
      841 tttcacgaaa ggcagttggc atgcttgctc ctacttggta catggcatcg atcacttcat
      901 ccacagggat tttagattcg atacctgcca aggccatgtc tgctgcgatg aaagcaaagc
      961 tagctcccat ggcattacgt ttgacacagg gaacttcgac caaacctgca acagggtcac
     1021 agatgaggcc tagcatattt ttaatgacaa aggcaatagc ttgactggcc tgataaggtg
     1081 ttccacctgc agccagagtc aaggcggcag cactcatagc agaggctgaa ccaacttcag
     1141 cttgacaccc accctcagca cctgagatgg aggcattgtt tgcgatgact agtccaaagg
     1201 caccagcagc aaagaggaaa tccaattgtt gctcgtggct gaggtctaat ttttcaatag
     1261 cagcagtgag aacggaaggg agacaaccgg cacttcctgc ggtaggagta gcgcagacca
     1321 agcccatttt agcattgtgt tcattgactg cgatagcatt tcgggcagca gagagaatcg
     1381 tgtaatctga taaagttttt tcgtttttga tgtagtgatc caatttggca gcatctccac
     1441 ctgtcaggcc actacgagat ttattttcat tgaggccaag ttggacagag gctttcataa
     1501 cttccagatt gcgttccatg agaaggaaga cttcttcacg ttcgcgaccg gtcaattcaa
     1561 actctgttgt aatcatgagt tctgcgacat ttccttgaaa gtccagatct gcttgctcga
     1621 ccaattcttt gatagaataa aacatgcttc ctcctattta aagaaattga cattgtggag
     1681 atgagggatt tttcgaattt cttcgatagc ctcatcacag ttgcgactgt caacttcgat
     1741 aatcataatg gctttttcac cagctttttc acgagtgaca ttcatctggg cgatattgat
     1801 accatagcgg gaaagcgcct ctgtaacaag ggcaatcata cctggaatat cttgatgaac
     1861 gatgatgata gtcggtgtat tcatattgag agagacggca aaaccattga gttcggttac
     1921 ctgaatattt cctccaccga tagaaatacc agtcacgctg atggtcttgt gggcattttt
     1981 aacagtaatt ttagtggtgt tagggtgagg ggcattgctg tctttctgaa tggtccagac
     2041 aatcttgata ccacgcttgt gggcaatttc cagactattt ggaatttcag gatcatctgt
     2101 atccattcct aaaatacctg caacaagggc taggtctgtt ccgtgaccac gataggtctt
     2161 ggcaaatgag ttaaaaagtt ggaattcaac ttctgtcgga gtatcatcaa aaatggaaga
     2221 gacaatcttc ccaatacgaa cagcaccagc ggtatggcta ctagatgggc caatcataac
     2281 tggtccgatg atatcaaaga cagattgaaa acgaagtgat ttcatcagtt tccccttata
     2341 aaaattctta tctctattat atcaaagaat gaggggcttg gctttaattg tggatgaaaa
     2401 cctttctaat acctcaaata gcataaaaat agtatctttt atgacaaaaa acaccttatt
     2461 tagggaaata aaaaataatt ttgtaatatt tctacataaa agtgtcaaga aacagtaata
     2521 tttaaagggt atgatagaac tatagaaaga aggagaattt tcgaatatga aatcaataac
     2581 taaaaagatt aaagcaactc ttgcaggagt agctgccttg tttgcagtat tttctccatc
     2641 atttgtatct gctcaagaat catcaactta cactgttaaa gaaggtgata cactttcaga
     2701 aatcgctgaa actcacaaca caacagttga aaaattggca gaaaacaacc acattgataa
     2761 cattcatttg atttatgttg atcaagagtt ggttatcgat ggccctgtag cgcctgttgc
     2821 aacaccagcg ccagctactt atgcggcacc agccgctcaa gatgaaactg tttcagctcc
     2881 agtagtaagt gaaacagttg tttcaactgt aagcggatct gaagcagaag ccaaagaatg
     2941 gatcgctcaa aaagaatcag gtggtagcta tacagctaca aatggacgtt atatcggacg
     3001 ttaccaatta acagattcat acctgaacgg tgactactca gctgaaaacc aagaacgtgt
     3061 agcagatgcc tacgttgcag gacgttacgg ttcatggact gctgctaaaa acttctggct
     3121 taacaatggc tggtattaag aactaacgaa caaataatat gtaaagagtc gaggaaatcc
     3181 ctcggctttt ttatctttcc ttcgcttggt aatagatctc tacttctttt ttgagatgag
     3241 acagcataga agtttcctcg gttagctcca gaagggagaa ccctttttgg ataagtttag
     3301 aatcgtctgt acaaatccca atacggacat agcagatagc cagcctatcg tagcttttct
     3361 tattcttggc gtcctccagt aaagtgtagc agatttgctt acacatgttt ttatcttgat
     3421 tgtatagata gagtgtggaa aggtttaata gaattgtcat tcgcaagtca tataaatgtt
     3481 gatagttttt atagacttct aggcgttgca atatttttcc agtgatgaga tggaggtatt
     3541 caatgggaaa actgaaaaga atggtattga ggatttttag atcactctca taccatgtat
     3601 cttgtttttc aatttttttc caaagttttt tgacaacctg ttctgcgtgt tttgatagtt
     3661 cccctgcccc gtgttgacgg agataaataa caacttcaag catatctctg atttcttcta
     3721 tagggagatc gtggtgggtc ttgaggtagt cttggcattt ttgaaataaa ttgacaagat
     3781 cgctggtccc gataatggaa cgcatattga gataggtttg cataatctct gtgcgttgac
     3841 ttggttgata aagttgacag atatattcaa actcttcaaa actcatattg atttgacgga
     3901 gaagaaattc catattttca tattttgggg ttgtcttgcc actttcgatt tttgataagc
     3961 tggttcttga gagaacaccc ccacagacct cttcttgggt cagccccttt gactcacgta
     4021 tttctttata gacctttccg aaatcataac gcatgatttt ctcctttctg tgaaaaaagt
     4081 taacaaacaa taaaattttg ttaaaaatat tgtatcatag caatgtaaaa agtaaaaaag
     4141 aaagtcgaaa taaatttgtg aaaaaagtta acgtaatttt aaaatgagct taataagagg
     4201 tatgatgtag gtagaaaata aagataggag aaaaagtatg aataaaaaaa tattttgtat
     4261 tctagtatgt attatatcat tgattagtct ggccataatc tttccatggg gctggtcgat
     4321 ataatgtaag ggagcttgag ttgttaaagg aggcttagtc cttggacaaa aatctgctgt
     4381 actacaatgc ttggaaagat atcaagaaca aagaatgata cgattgaaaa taaactgatt
     4441 caagaactac tgggcagtga ttgaggtttg ggtgacatca aagaaaagtt agattaattc
     4501 taaagaattg agtatttcta tgttaaaaaa atatccttgt acgatgcaac atgatcagtc
     4561 agattgtgct gcggcagttg tttcaacagt tcttttatct tacaaaaagg aactatcaat
     4621 catgaagatt cgggaaatta ttggtacaga catgtatgga acgactgtca gtggtattgt
     4681 ttcaggtctg aataagttga attttacagt aaaagctgtt cgagtagcac tggaagattt
     4741 gactccaaaa ttaacatttc ctgcgattct tcaagttaag aatgatttag gtcaaaatca
     4801 ttttgtggta ttacatagta taaaggagaa aataaatgga actcgtatta ccaaataatt
     4861 atgttgtgat tgatgaagaa gagatgatgt accttgatgg gggggctata tatataccca
     4921 ggtgggcaat tacaggagcc attactggtg cagcatatgc agcattagca gcagcaggag
     4981 gtggaggcct tcaactagtt cttgcatctt atggattacg ctccgcactg gtagctggga
     5041 ttgttaaagg tttaggagta ttaggaattc atattggaaa tgcttttgca aatactgtta
     5101 ttagaagtat tgcatctgct ggaattggtg ctggagctga ttggatttta ccaatattat
     5161 tgatggctgg gatgggcgac gtgataatca attgagaata ggataatagt attatgatgg
     5221 ttgttttaat ttcagttatt gttgcattcc tgtaccataa aattacagag tatgtcaaca
     5281 acaggaaaat tgatattgtt atttttctat cattgctgat ttctcatttt atttggaatt
     5341 actatttttt accaattgaa atattgatag caatcagtgg agcaaattta ttattaagtt
     5401 ttttaaaaaa attacagatt aaataatatt attccatatg acatatcaac taggtcatta
     5461 gattttattg aagatataaa ttaaaaacga ggttgggaaa aaactcaatt tgaaagtgaa
     5521 attgagtaaa tttttctatt atataacgca tattatcaag atttttgaac acctgataat
     5581 atgcactttt cttattttaa agattttttg cctttcttca tttcttgaat gaattggaga
     5641 gatgacttta tttaggtgtt tgacattact atagatagga tttagcagta ctaatatgaa
     5701 ctcatattat aggtgcagac ttaaattttg gaagcaagct aaaggatatc ttatctaggt
     5761 aactaagtgc tataaacaaa gtcaacgatc acttgttagg aaacgatcct aactatgctt
     5821 aataaaaaag gagaaaataa atggaactcg tattaccaaa taattatgtt gttcttgagc
     5881 aagaagagat gatgtatctt gatgggggtg gtgttggttg taactggtgg aacaaacgtg
     5941 ataatattgc tgcagctgca gtttctggag ggatgtcagt ataccagaca tatgccatta
     6001 aaaagttaat tgctaatcgt ggtatgatga gccgagtcgt tagaagtgct ataacaagat
     6061 atattggtgg agttagtatg gcaactatta ctaatgctct taatattgcg gctactgttg
     6121 ctgaagtttt ctcattagga ggagccattg catatggttt agatatcgta gacggtaaat
     6181 ttgatgg
//
LOCUS       DAVBEM010000080         4871 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVBEM010000080 DAVBEM010000000
VERSION     DAVBEM010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4871
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.080"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            191..409
                     /locus_tag="VQ548_002020"
     CDS             191..409
                     /locus_tag="VQ548_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HET2654811.1"
                     /translation="MKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVS
                     AIDSSEAMLLPTINVLELLDKSQPFEEE"
     gene            1454..2446
                     /locus_tag="VQ548_002021"
     CDS             1454..2446
                     /locus_tag="VQ548_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2654812.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYDGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            2448..3266
                     /locus_tag="VQ548_002022"
     CDS             2448..3266
                     /locus_tag="VQ548_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HET2654813.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            3268..4053
                     /locus_tag="VQ548_002023"
     CDS             3268..4053
                     /locus_tag="VQ548_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2654814.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            4092..4370
                     /locus_tag="VQ548_002024"
     CDS             4092..4370
                     /locus_tag="VQ548_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HET2654815.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTRFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            4355..4552
                     /locus_tag="VQ548_002025"
     CDS             4355..4552
                     /locus_tag="VQ548_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2654816.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
BASE COUNT         1399 a          796 c         1022 g         1654 t
ORIGIN      
        1 ggctagtttc ctagtttgct ctttggtttt catttagtat aacagattgt tagaagttgg
       61 tttaaatttc ctaatcagtt tgttcacatt taccttcgat atattatatc ccatagttaa
      121 ggttggtcat acagatgatt atagtcatgg agccgtaaaa cttagtgttt ctttagttga
      181 caaagatgcc atgaaaaaaa tatctgtaac tgtaatagga tattttgaaa taaatataga
      241 tgaaaatatc accgatattc tatacgtaaa tggtactgct attctttatc attatttacg
      301 ttctattgtt tcaatagttt cggcaattga tagcagtgaa gcaatgttgc tacctaccat
      361 taatgtttta gagttactag ataaatctca accttttgaa gaagaataat ttattagctc
      421 actaaattga gggtaaggaa aagtaaaatc agtaagaaaa atgtcttgca ttatacagca
      481 accttttggg aatgagtaga tggattgaat aaaattttat taagagtgga tgatttatct
      541 gtagattatt attggacagt tagtcttgaa gtagtctaag aattaggtta taatcagtag
      601 aatccttgct aataatgagg aggttagttt atgtatagta gactgaatct aaaatagtac
      661 gaaacaattg ctaaaacatt tatagaaatt aattttactt tcccaatcga tttgttctca
      721 tcttatttca atccgctata tattatggta tcgaatcttc atcagaatga taaaattaat
      781 caattgatat ctgattacaa acagaatatg aaagcttttt atatcactat tgaaaaattt
      841 atacgagatg atgaaagcct taagtgttat tttataaagg ttatttcaag tcgttccaag
      901 gtaacaagtc tagatcagat tgaagctgat aaaacgatac aaagaaaata ttcaagtgag
      961 ctaaaaaaat ttattggatt ttataatgag attatttgtg aggaaaatag tttcctacat
     1021 gtacgaaaga ggtggtcgag ttggtttagg tagtcgatgc gtgagttgat aattctcagg
     1081 gtatggactt ctttttcatg aatgaggtaa aagagcaggt attgtttaga gacaatcatt
     1141 ctgagcatat tttctggata gagggagtat ccgattttat gatcaaagtt aataccgccc
     1201 tctggtgaga agatgagtag gttggtaatt taaactatta aacagaattt ttgattaaaa
     1261 gtattatttt atgagagaaa tcctaatttc acaatccata ggcaaactct tgcatttcgt
     1321 tttttattgg actataatag gttggtataa agccttttgt agtaataaaa tgtagaaggt
     1381 gtagaaagca aggatttaga atatttgtag ttaaaaacac aatgttgcta ttccttacga
     1441 tagggagata gatatggcaa tgatagaagt ggaacatctt cagaaaaatt ttgtgaagac
     1501 tgttaaggaa ccgggcttga agggggcttt gcgctccttt attcatcctg aaaagcagac
     1561 ctttgaagcg gtcaaggatt tgacctttga ggttccaaaa gggcagattt taggatttat
     1621 cggggcaaat ggtgctggga agtcgacaac cattaaaatg ctgacaggaa ttttgaaacc
     1681 aacatctggt ttttgtcgga ttaacggcaa gattccccag gacaatcggc aagattatgt
     1741 caaagatatt ggcgtagtct ttggacaacg cacccagcta tggtgggatt tggctctgca
     1801 agagacctac actgtcttaa aagagattta tgatgtgcca gactcgctct ttcataagcg
     1861 tatggacttt ttgaatgaag tcttggattt gaaggacttt atcaaggatc ccgtgcggac
     1921 tctttcactg ggacaacgga tgcgggcgga tattgcggcc tccttgctcc acaatcccaa
     1981 ggttcttttt ttagatgagc cgaccattgg tttggacgtt tcggttaagg ataatattcg
     2041 tcgggcaatt actcagatca atcaagagga agaaactacc attcttttga ccactcacga
     2101 tttgagtgat attgagcaac tttgtgatcg gattttcatg attgacaagg ggcaagagat
     2161 ttttgatgga acggtgagcc aactcaagga gacctttggt aagatgaaga ctctctcttt
     2221 tgaactgcta ccaggtcaaa gtcatctcgt ctctcactat gacggtctgt ctgatatgac
     2281 cattgataga caaggaaaca gcctcaacat tgaatttgat agttctcgct accagtcagc
     2341 tgacattatc aagcaaaccc tgtctgattt tgaaatccgc gatttgaaga tggtggatac
     2401 ggatattgag gatattatcc gtcgcttcta ccgaaaggag ctctaggatg atcaaattgt
     2461 ggagacgtta taaacccttt atcaatgcag gggttcagga gttgattact taccgagtca
     2521 actttattct ctatcggatt ggcgatgtca tgggggcttt tgtggccttt tatctctgga
     2581 aggctgtctt tgattcttcg caagagtctt tgattcaggg cttcagtatg gcggatatca
     2641 ccctctacat catcatgagt tttgtgacca atcttctgac tagatccgat tcgtccttta
     2701 tgattgggga ggaggtcaag gatggctcca ttatcatgcg tttgttgcga ccagtgcatt
     2761 ttgcggcctc ctatcttttc accgagcttg gttccaagtg gttgattttt atcagcgttg
     2821 gccttccatt tttaagtgtc attgtcttga tgaaaatcat atcgggtcaa ggtattgtag
     2881 aggtgctagg attaactgtc atttatcttt ttagcttaac gctcgcctat ctgattaact
     2941 ttttctttaa tatttgcttt ggattttcag cctttgtgtt taaaaatctt tggggttcca
     3001 acctacttaa gacttccata gtggctttta tgtcggggag tttgattccc ttggcattct
     3061 ttccaaaggt tgtttcagat attctctcct ttttgccttt ttcatccttg atttatactc
     3121 cagttatgat cattgttgga aaatacgatg ccagtcagat tcttcaggca ctccttttgc
     3181 agttcttctg gctcttagtg atggtgggat tgtctcagtt gatttggaaa cgggtccagt
     3241 cctttatcac cattcaagga ggttagtatg aaaaaatatc aacgaatgca tctgattttt
     3301 atcagacaat acatcaaaca aatcatggaa tataaggtgg attttgtggt tggtgtcttg
     3361 ggagtctttc tggctcaagg cttgaatctc ttgtttctca atgtcatctt tcaacatatt
     3421 ccattcctag aaggctggac ctttcaagag atagctttca tttatggatt ttccttgatt
     3481 cccaagggaa tggaccatct cttttttgac aatctctggg cactagggca acgcctagtc
     3541 cgaaaagggg agtttgacaa gtatctgact cgtcccatca atcctctctt tcacatccta
     3601 gttgaaacct ttcagattga tgccttgggt gaactcttag tcggtggtat tttattggga
     3661 acaacagtga ccagcattgt ttggactctt ccgaaattcc tgcttttcct agtttgtatt
     3721 ccttttgcga ccttgattta tacttctctt aaaatcgcaa cagccagtat cgccttttgg
     3781 actaagcagt caggcgccat gatttacatc ttctatatgt tcaatgactt tgctaagtat
     3841 ccgatttcta tttacaattc tcttcttcgt tggttgatta gctttatcgt gcctttcgcc
     3901 tttacagcct actatccagc tagctatttc ttacaggaaa aggatgtgtt ctttaacgta
     3961 ggaggtttga tgttgatttc tctggttttc tttgttattt cccttaaact ttgggataag
     4021 ggcttagatt cctacgaaag tgcgggttcg taaaagctaa agtaagacta aaatcaagaa
     4081 agaaacttat gatgtttgta attgaagaag tcaaggatga aaatcaaaaa aaggcagttg
     4141 tagctgaggt tttgaaggat ttgccagaat ggtttggaat cccagaaagc acacaagcct
     4201 atatagaagg aaccacgaca ctgcaagttt ggaccgccta tcaggagagt gatttgacta
     4261 gatttgtaag cttatcctat tcgagtgaag attgtgcaga gattgattgt ctcggcgtaa
     4321 aaaagcttat caaggtagaa aaattgggag ccaattgctt gctactttag agagtgaagc
     4381 tcgtaaaaaa gttggttatc tgcaggtcaa aacagtggca gaaggttcta ataaagatta
     4441 tgatcgaaca aatgactttt atcgaggtct tggctttaaa aagttagaga tttttcctca
     4501 actatggaat ccgcaaaatc cttgtcagat tttgattaaa aagcttgaat aatattactt
     4561 gacatctatt ctcagagtgc catactgtaa gtgtaatcgc cgatttagct cagttggtag
     4621 agcaaggcac tcgtaaagcc taggttatag gtagataaac gactgaggag ttgaaaaaat
     4681 agataggtag aagataaccg ttaagcctta ttcttagcgg ttatttatat tgtttaatag
     4741 cgctgatatt tcatcaatta tgcctgtttt cgtgtttctg gtagttgttc aagtttattg
     4801 ctactatttt tgatggtatg aatgtgctta taatgtatcc cggttaacga aagttttgga
     4861 cttatactct t
//
LOCUS       DAVBEM010000081         4599 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVBEM010000081 DAVBEM010000000
VERSION     DAVBEM010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4599
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.081"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            39..194
                     /locus_tag="VQ548_002026"
                     /pseudo
     CDS             39..194
                     /locus_tag="VQ548_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(187..360)
                     /locus_tag="VQ548_002027"
     CDS             complement(187..360)
                     /locus_tag="VQ548_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HET2654817.1"
                     /translation="MNIKKRVLSAGLTFASVLLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYTDNIVN"
     gene            complement(518..2125)
                     /locus_tag="VQ548_002028"
     CDS             complement(518..2125)
                     /locus_tag="VQ548_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HET2654818.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            2278..3762
                     /locus_tag="VQ548_002029"
     CDS             2278..3762
                     /locus_tag="VQ548_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HET2654819.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFLNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGISPADRKVAVVARQKAEETGGPALALELPNGDIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            3857..4339
                     /locus_tag="VQ548_002030"
     CDS             3857..4339
                     /locus_tag="VQ548_002030"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HET2654820.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
BASE COUNT         1332 a         1062 c          868 g         1337 t
ORIGIN      
        1 cctttctcga gcttagctga cttcaaccca ctacagttga caaagagcct aagcttttac
       61 ctcttcctcc ctactcacct gagtacaatc ctattgagaa aacatgggct catatcaaaa
      121 agcacctcaa aaaggtatta ccaagttgca atacctttta tgaggctctt ttgtcttgtt
      181 cttgtttcaa ttgactatat tatcagtgta atagtctaat agatagttaa atgtagttgg
      241 atttccacta aaggttgatg agtaagtttt tgtatctgaa cctgattggc cgcaagcagc
      301 taaaagcaaa acagatgcaa aagtcaggcc tgcactaagg acacgcttct ttatgttcat
      361 cttctttctc cttaatagtg ggaatttgta aagttaattg aatttcgaga atgaaagttt
      421 ataaaccttg gttataaaaa acaaaggatt tctgctttta tacagtcctc ccttgttttt
      481 atatgatttc aattttaaat ttttctgcaa aaaatattta tagtaattcc acacagaaag
      541 catcccatgg aactaagatt tgtttttcaa agacttcttg agctagggtg ttttcaatca
      601 agacagattt gacttttcct tctactgtca agtcttgctc ttcattggac aagttagcca
      661 caactaggaa gcgacggtcg ccatccttac gtatataagc aaagacctta tcagccgtat
      721 caagcaattc aaagtcagct cgaactagcc agctattctc cttgcgaatt tggaccagtt
      781 tctgataggt atagaaaata gaatctggat ttgccagcgc ttcttggaca ttgatcatct
      841 cgtaatttgg attaaccgcc aaccaaggtt gacctgttga gaaaccagcg tttttgctct
      901 cgtcccattg cataggggta cgggcattgt cacgtccaat aacacggata ctgtccatga
      961 tttcttcaat cggaacacct ttttcaagag cctcacgcgc atagttgaga gattcaatat
     1021 cttctacttg atccagtgtt tcaaacggat agttggtcat cccaatctcc tcaccttggt
     1081 agatataagg agttcctctc ataagatgaa gcaagattgc aaaggctttg gcagattttt
     1141 cgcggtattc ttggtcattt ccccagattg agacaatacg agggaggtca tggttgttcc
     1201 agaagaggga attccagccg tcctcaactc ctaactctgt ctgccatttg ttgaagattt
     1261 cttttaactt agcgatattc agctcttttt gatagtgcca tttaggctga ccttcctgat
     1321 actgaagacc gatatgttca aactggaaga ccatagacaa ttcttgcccc tttggatcag
     1381 agtagagctt ggcaatctct ggcgttgctc cccaagtctc ccctactgtc aagagatcct
     1441 tatctccaaa ggtcgcctga ttcatttcct tgagataggg atggagcata ggaccattat
     1501 tgactacctt ctcgtcagga attttgccaa tcatgtcaat aacatccata cggaaaccac
     1561 caataccctt atcaatccag aagttcatca tctcataaat tttctggcga agtttttcat
     1621 tttcccagtt gagatccggc tgtttcttgc tgaaaaagtg gagatagtat tgacctgact
     1681 tttcatcgta ttcccaagca gacccactaa agatagaatc taaatcgtta ggctcatccc
     1741 gccagatata gtagtctcgc tcagggctat taggattttc acaggcctct acaaaccagg
     1801 catgctcatc cgaggtatga ttgaccacca agtccatgat gatacggata tcacgcttct
     1861 tagcttctgc aatcagctga tccatgtcct ccatggttcc aaaaatagcc gcaatcgctt
     1921 gataatcagc aatatcgtag ccattatcat ccatagggct gtcataaacg ggagaaagcc
     1981 aaattgctgt gattcctagc ttggctagat agtccaactt actggtaatt cctggcaaat
     2041 cgccaattcc atctccatta ctatccataa aactctttgg atagacttga tagactacgg
     2101 cattatgcca ccatttttct tgcatctgtt tacctcatta ttttcataat ctatagtcta
     2161 tgatagcact ttttaaaatt ttgtgcaagc gtttgcttaa tctttttaat ttctttttta
     2221 gctccgtagt ttcctaactt ccaatttttt attataatag agtccagagg taaaaaaatg
     2281 aaaaaacaag cttttagttc tgaacagtat ttgaatttac aacgcgacca tattttggag
     2341 cgcattaacc aatttgacgg caagctctac ttagagtttg gcggtaaaat gttagaagat
     2401 ttccacgctg ctcgtgtcct tcctggttat gaacctgaca acaaaatcaa gctcttgcaa
     2461 gaattgaaag agcaggttga ggttgtgatt gccattaatg ctagcaacat tgaacattcc
     2521 aaagcacgtg gcgacttggg catttcttat gaccaagaag ttcttcgttt gattgacaaa
     2581 ttcaatgaat tagggatttt tgttggttcc gttgtcatta cacaatacgc tggccaaccc
     2641 gctgcagatg ccttcctcaa ccaacttgag aaaaacggaa ttgattctta tcttcattat
     2701 ccaatcaaag gatatccgac ggatatggat cacatcattt ccccagaagg catgggcaaa
     2761 aacgactaca tcaaaaccag tcgcaacttg attgtcgtaa ccgctcctgg acccggttct
     2821 ggaaaattgg caacgtgtat gtccaatatg taccacgacc aaatcaatgg catcaagtct
     2881 ggctacgcta aatttgaaac cttccctgtt tggaatcttc cccttcatca tccagttaac
     2941 ttggcttatg aagctgccac agctgacctt gatgatgtca acatgattga ccccttccat
     3001 cttcaaacct atggagaaac cactgtcaac tacaaccgtg atatcgaaat cttcccagtg
     3061 ctcaagcgca tgttggaacg tattctcgga aaatcaccat acgcttcacc gacagatatg
     3121 ggtgtcaaca tggttggttt cgctattaca gatgacgagg ctgctgtcga agcttctaaa
     3181 caagaaatca tccgccgtta ctatcaaaca gttcttgact tcaaagctga aaaagttggc
     3241 gaagctgccg tcaagaaaat tgagttgctc atgaacgacc tcggtatctc acctgcagac
     3301 cgtaaggttg ctgtcgttgc gcgccaaaaa gcagaagaaa ctggcggacc agccctagct
     3361 cttgaattac caaatggtga cattgtcact ggtaaaaact cagaactctt tggccctaca
     3421 gccgctgcct tgatcaacgc catcaaaaaa tcagctgaca tcgctaaaga agtaaaacta
     3481 atcgagcctg aagttgttaa gccaatccaa ggacttaaaa tcgatcatct cggtagccgc
     3541 aatccacgcc ttcattcaaa tgaaatcctg attgcacttg ctatcacagc tacagaaaat
     3601 cctgatgctg cccgcgctat ggaagaactc ggcaacctca aaggaagcga agcccactca
     3661 accatcatct tgactgatga agacaagaat gtccttcgta aactgggtat caacgtaacc
     3721 tttgacccat actaccaata cgaccgctta tatcgtaagt aaagatttca acctctccag
     3781 cctcggagag gttttctctc tgtctcagga gcaagcttta tgatataatg agagaagaaa
     3841 actgaaagga tttaccatgt caaaagaagt tattgtcgaa agttttgaac ttgaccacac
     3901 cattgtcaaa gcaccctatg ttcgcttgat tggggaagaa acaggaccaa aaggagacat
     3961 catctccaat tatgatattc gcttggtgca accaaacgaa gactctatcc ctactgccgg
     4021 ccttcacact atcgagcacc tcttagccaa actcatccgt acccgcattg acggcatgat
     4081 tgactgttca ccatttggtt gccgcacagg cttccacatg attatgtggg gacgtcacac
     4141 cagtgctaaa atcgcagctg ttatcaagga ttcgctcaag gaaatcgctg aaactactac
     4201 ttgggaagat gtcccaggga caaccatcga atcttgcgga aactacaagg accacagcct
     4261 cttctctgct aaagaatggg caaaactcat cttggaacaa gggatttcag atgatgcctt
     4321 tgaacgtcat gtgatttaaa atcgagtagg ggataatctc tagcccctct cacaccaccg
     4381 tacgtgccgt tcggcatacg gcggttcaac taacttttaa cgcatgtcgt tcaaggtaat
     4441 aatccaaaca cgaaaccaat ccacgttttt caaggactgg ttttgatata gcacgtttaa
     4501 gtaccgactt ctgagctact atagtggatt gaaactagaa tagttcacct ctgcttctaa
     4561 aacattgtta gaaatcgatt tgactatcct gatcgattt
//
LOCUS       DAVBEM010000082         4552 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVBEM010000082 DAVBEM010000000
VERSION     DAVBEM010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4552
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.082"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(112..549)
                     /locus_tag="VQ548_002031"
     CDS             complement(112..549)
                     /locus_tag="VQ548_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HET2654821.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(634..3267)
                     /gene="polA"
                     /locus_tag="VQ548_002032"
     CDS             complement(634..3267)
                     /gene="polA"
                     /locus_tag="VQ548_002032"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HET2654822.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3520..3873
                     /locus_tag="VQ548_002033"
     CDS             3520..3873
                     /locus_tag="VQ548_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET2654823.1"
                     /translation="MILRHLGISPTNDLVAKKIFSNPEITCQFIRDMLDLPAKNVTIL
                     EGSNIHVLPSMPYSAQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQV
                     NQNLEKIRQREGDTH"
     gene            4088..4204
                     /locus_tag="VQ548_002034"
     CDS             4088..4204
                     /locus_tag="VQ548_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET2654824.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            4197..4430
                     /locus_tag="VQ548_002035"
     CDS             4197..4430
                     /locus_tag="VQ548_002035"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654825.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
BASE COUNT         1385 a         1096 c          837 g         1234 t
ORIGIN      
        1 gtatctacaa cctcaaaaca gtgttttgag cagcccgcga ctagtttcct agtttgctct
       61 ttgattttca ttgagtataa cacaaaaggt agcccatcag ctaccttttt cttatgcttc
      121 ctcaatcaag cgagtatgtt ctctcttgat acagcgattc atcacgatat catcacatcc
      181 accatcacgc aaaatctctt tcgcttctaa actttcaagt cctagctgtg cccaaaaaat
      241 cttggcatca gctttgagaa aatcacgcgc cacatcgggc agaaattcac tgcgacgata
      301 aacattgaca atatctacag gaaaaggaat ttcagcgagg ctagcataag ccttttcacc
      361 caagatttcg ccacctgccg ccttgggatt gactgggatg attttatagc cccgagcctg
      421 catttccttt gtcactcgat tgctggttgt ttcttcacgg tcagacaaac ccaccacagc
      481 aagggtttta ctcgttgcga gatactgacg aatcacgcca tcacttggat tgataaattc
      541 ttgactcata gaaaacctcc tttttcatca gtatagcaca ttttgaaaag gtttgcagaa
      601 ttctactaca aaaaaggagg actagccccc tttttattta gcctcgtacc aggttgcccc
      661 ttcattctca tctgcgataa gaggaacact gagttgaatg gcttcttcca tggtttgttt
      721 caccaatttt ttcatctcta ccaattcaga tttaggcact tcaaggacga tttcatcgtg
      781 cacttgtaac agcatcttag tctgataacc acctgcaacc aaggctttat ccagctgaat
      841 catggcaatc ttgagaatat ctgctgccga accctggata ggtgagttga tagcagttcg
      901 ctccgcaaaa ccacgaatat tgaagttgcg cgaattgata tctggcaact cacggcgacg
      961 cttaaagagg gtctctacat agcccttatc acgcgcctcc cgcaccactt catccatgta
     1021 gtttttaata cctggaaaac gttcaaagta ggtatcaatg taggctttgg cttccttacg
     1081 actaattccc aaattattag acaagccaaa gtctgaaatc ccataaacca ctccaaagtt
     1141 aactgccttg gcattgcgac gatcatttgc agtcacatta tcaggacgct caatgccaaa
     1201 gacccgcatg gctgtcgaag tatggatatc tgccccctct tggaaggcct taatcaagtg
     1261 ctcatcctta gaaatatgcg ccaaaacgcg caattcaatc tgtgaatagt cagagctgag
     1321 tagcacacta tcctcccact ctggcacaaa agccttccga atcaagcgcc cttgttccaa
     1381 tcgggcagga atattttgca agtttggatc cacactagac aaacgcccgg tctgggtcaa
     1441 atcctgcata tagcgagtat gaatctttcc atcagccaaa atccagtcct gcaagccaat
     1501 tacataagta gattgaatct tagcaatttg acggtaatcc aggattttct taacaatcgg
     1561 agcaatagga gcgagacgct ccaacacatc cactgctgtc gaataacctg tcttggtttt
     1621 cttagtgtat tctagaggaa gtcccaattt ctcaaagaga agcacgccca actgcttagg
     1681 cgagttgaca ttaaactcct caccagccag ctcgtaaatc tcttgagtca gtttttcaat
     1741 gacaagctca ttttcagcct gcatctcaag caaggtctct ttcttgacca caatcccagc
     1801 aatttccatc ttggcaagaa caaaagccag aggttgctcc atatcataaa gaagctctaa
     1861 ttgcccattt tcgctgagtt tttcaagtaa aataggctct gtttctacca aaacagcaag
     1921 tttacaagct aagtgttcca agaatttctc acgttcagga atggcctttt taacaccctt
     1981 accgtagaaa gtttcatcat caaccaagta agtctgacca taaagactag cgatggtcgc
     2041 aatttcattg tcctccacag tcgaaaggag gtatttagcc aaacggatgt caaaagcagg
     2101 cgcctgcaaa tccacaccaa aacgttgcaa aagaacttta accttcttaa agtcataaac
     2161 tctcagagat gttttttcta agaaatcctt gaaaatcggg tcttgcaaca gctcaagctt
     2221 gtctgtggca tagagcttat ccccacaaga ccaggcaaat ccaaccaaat tatccgtatg
     2281 ataattctca ccaaaaagct caaagtggaa gatagactct tcactcagca tatcttgact
     2341 gatttggtca acaatagtaa aatccaaacc ctcagccaca tcagctgacg acacatttaa
     2401 agcctgcttg agctgtttga atcccatctc atcgtaaaat ttcccaagat tttcaacatc
     2461 tggaccacta tagaccaagt cctctaaacc aatcgcaatc ggtgccttgg tatcaatggt
     2521 cgctagtgtt ttagacaaaa aggcctgttc cttgtcattg atgagatttt ccttcatctt
     2581 agaagtcttc attccatcaa tattttcata aatcccctca agcgaaccat gctccagcaa
     2641 gagcttaata cccgtctttt caccgacttt ggtcacccca gggatattat ccgacttatc
     2701 acccatgagc gccttgagat cgataaactg agctggtgtg aggcccattt cttccatgag
     2761 gtaatctggc gtaaaggcct caaactcagc cacacctttc ttggaaattt caaccaccgt
     2821 atgctcatcc gtcagctgaa tcaaatcctt gtccccactg acaatggtaa tatcaaaacc
     2881 atcctgctct gctagcttat ccaacgtccc aatgatgtca tccgcctcat actgagccag
     2941 ctcatagtga cgaatcccca tatgatccag caactcacga atgaaaggaa attgctcacg
     3001 aaactcatca ggagtcttgg cccgaccacc cttatagtcc gcatacatct ctgtccggaa
     3061 ggtcgtcttt cccgcatcaa aagccaccaa aatatgactc ggctcaaccc gctccaacaa
     3121 atgactcaac atcaactgaa aaccataaat cgcattggta tgcaaaccag ccgcattctt
     3181 aaaacggtcc aactgctgat acagcgcaaa aaacgcccga aaagctacag aagacccatc
     3241 aatcaataat aattttttct tatccataca cccattataa aggaaagaat caaaaaatac
     3301 cattgggaag agctagagca agtatttttc aaactttttc cgaataaata gatagagcca
     3361 gagaatttag taaacctaga tttaaaaatg tgctataata tagtatattg aatctataat
     3421 agtacacctt gactgctaaa atatttctat aaattaattt gactttcctg atagagttgt
     3481 tcacatctta tttcaattca ctatagaagg aggaaaagga tgattctcag acatctggga
     3541 attagcccga ccaatgactt ggttgctaag aaaattttca gcaacccaga aatcacttgt
     3601 caatttatcc gcgatatgct ggacttgcca gccaaaaatg tgactatttt ggagggaagt
     3661 aacattcatg tcttgccttc catgccctac tcagcgcagg atttttatac cagtatagac
     3721 gtcttggcgg agttggataa cggtactcaa gtaattattg agattcaagt ccatcatcag
     3781 aattttttca tcaatcactt gtgggcttac ctgtgcagtc aggttaatca aaatcttgaa
     3841 aaaattcgtc agcgagaagg tgatactcac tagatctaca aacacatcgc tcctgtttac
     3901 gtcattgcta tcgtggatag taattatttc tcagatgacc tggcttttca tagctttagt
     3961 atgcgcgaag acacaacagg tgaggtattg gcgattacca acaatggaca ggaaaaccat
     4021 ctggttaaga tggcattctt ggaattaaaa aatacagaga aaccagcaaa gacaaggttc
     4081 gcaagccatg gttggagttt ttcggcaaca agccctttac ccagcaaccg caacgagcca
     4141 ttacccaagc aaatcaactg ctggactaca agagctggtc cgaggaggac aggaaaatgt
     4201 ttagtcaact acatatgcga gaagaacaag tcttgttagc acaggactat gccttggaaa
     4261 ctgctagggc tgaaggcctt gaacaaggac tagagcgtgg gaaagttgaa ggaagggcag
     4321 aaaggaaact ttttgccttc ctagacatag tacgccaagg tcttctgact tctgaggttg
     4381 ccagccagca attaggtatg tcagtatctg aatttgaggc actgttgtaa aatggctcca
     4441 taatatccat agtgggtaaa tcccctatgg atattatgga gcctattttt gtgtagaaaa
     4501 aaagtcccat atgacctata atgaaaagcg acaaaacaac tcattaaaaa ga
//
LOCUS       DAVBEM010000083         4438 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVBEM010000083 DAVBEM010000000
VERSION     DAVBEM010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4438
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.083"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            <1..119
                     /locus_tag="VQ548_002036"
     CDS             <1..119
                     /locus_tag="VQ548_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2654826.1"
                     /translation="QQGFTDRLVGYSSSIALVFTTLIGMISLVQRRVLKEDD"
     gene            121..966
                     /locus_tag="VQ548_002037"
     CDS             121..966
                     /locus_tag="VQ548_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2654827.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRLAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            976..2295
                     /locus_tag="VQ548_002038"
     CDS             976..2295
                     /locus_tag="VQ548_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET2654828.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(2503..2575)
                     /locus_tag="VQ548_002039"
     tRNA            complement(2503..2575)
                     /locus_tag="VQ548_002039"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2540..2542),aa:Lys,seq:ctt)
     gene            complement(2839..4110)
                     /locus_tag="VQ548_002040"
     CDS             complement(2839..4110)
                     /locus_tag="VQ548_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HET2654829.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWIKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
BASE COUNT         1294 a          809 c          976 g         1359 t
ORIGIN      
        1 atcaacaagg ttttactgat cgtcttgtag gatattctag ctcaatcgct ttagtattta
       61 caacgttaat tggtatgatt agcttagtac aacgtcgcgt tctgaaggag gatgactaag
      121 atgaaacgat ttaaaccaac aacaatctta gaatatattc tgttaacttt attggcagga
      181 ctcttccttt ttcctatggt ttggatggta gtttcagcta tgaagccaga agcggatgtt
      241 tataaaaatt tgactagttg gcaagccttc ttaccaagtt taaatcccgc tgattggttt
      301 aaaccttatc aggaagtatt tgagcgcttt agtattttta catatctagg gaacagcatt
      361 ttttatgctg gaacgtttgc tattggttct attattgtca atgcactggc cggtttcgct
      421 tttgcaaaag tcaatttttc aggtaagaaa attttatttg gtttcttact tgctttactt
      481 attattccag tggaaactgt gttaattcca caatttacca ttatcaattc cttaggtttg
      541 gtcaataatc gtcttgcagt tattattcca ggattggcga gtgtatttaa tatttactta
      601 tttaggaatt tctttattgc aattccagaa gagattcttg agtctgcaaa gatggacgga
      661 gcaagtatcg ttagaatttt ctttagaatt atgcttccaa tgtctaaacc tgcagttgct
      721 acagttggtg ttttatcatt tatttcaagc tggaatgatt atatctggcc attgatggtt
      781 ttgacagatt cttctaaatt ttcaatgcag gttgcaatta caactattaa tacaactcaa
      841 ccagtttata tcaatcaggt aatggctgta ttaactattt caacgattcc gttgattttg
      901 gtctatgtag tcgctcagaa atatattgtt caaggtctgg gtggttccgg aactggaata
      961 aaataggata tacttatgat aaataaaaca tttacagtag aaaaagccaa tcgttttata
     1021 gcagaaaata aacatctcgt taatactcaa tataagcctg aagaacattt ttcagctgag
     1081 attggttgga tcaatgatcc aaatggattt gtctattttc gtggagaata ccatctcttt
     1141 tatcaattct atccatatga tagtgtttgg gggcctatgc actggggaca tgctaaaagt
     1201 aaggacttgg tgacttggga gcacttgcca gtggcacttg ctcctgacca agattatgac
     1261 cgaaatggtt gtttctcagg ctctgccatt gtcaaggatg atcgcctctg gctcatgtac
     1321 actggacata tcgaagaaga aaccggtgtc cgccaagtgc aaaatatggc attttcagat
     1381 gacgggattc actttgaaaa gatttcccaa aatccagttg caactggatc agacttgcca
     1441 gatgagttga ttgctgctga tttccgtgat ccaaaactct ttgaaaaaga tggacgctat
     1501 tactccgtag tagctgccaa acacaaggat aatgtgggct gtatcgttct actagggtcc
     1561 gataacctag tagaatggca gttcgaatcc atctttttaa aaggaggaga acaccaaggc
     1621 tttatgtggg aatgcccaga ttacttcgag ttagatggga aagattgcct tattatgtca
     1681 cccatgcgtt atcagcgtga gggagactca tatcataaca tcaactcatc gcttttgttc
     1741 acgggtaagg tagattggag agaaaaacgt tttatcccag aatcagttca agaaattgat
     1801 catggccaag acttctatgc gcctcaaaca ttgttggacg atcaaaatcg tcgtatcctg
     1861 attgcttgga tgcagacatg ggggcgtacc cttccaaccc atgaccaaga acacaaatgg
     1921 gcatgtgcca tgactttacc tagaattcta agattggaag atggcaaact aagacaattc
     1981 cctgttaaaa aaggccaata tcaaatccaa atagataaag attgtcatta ccacttagga
     2041 aatgatacag attatcttga atttggttat gacagtaatg cgcagcaagt ttacattgat
     2101 cgtagccatc ttattcaaaa aattctaggt gaagaagaac aggacactag tcgacggtat
     2161 gtagatattg aagctaaaga attggaagtt gttctagata aaaattccat cgagattttt
     2221 gtcaatcaag gtgaagcaag cttgactgca acttattact taacggtgcc agctgagcta
     2281 tcacgaattg attaaaaatt aagttatttc tcctaaagaa aaagttctct ttctaaaata
     2341 gtggaaagag gactttttgt gttttgggta tataagctta gtttatggta tttgtaaaat
     2401 tggtgttgga ttatgattta agctagtttt ctaaagaatt tgaaaaaaat tttatttaag
     2461 caaaaaaacc ttggttccaa ggcttttcct gttgtattta gatgccccct acagggatcg
     2521 aacctgtgac ccacggatta agagtccgct gctctgccag ctgagctaag gaggcaaaga
     2581 aaaagctgta ttggtgccga aacttcacgg tttgtattga acccgcgcaa ttaagcaggt
     2641 gggcaactcg ctctaactga agctgtttcc gtgtgagacg gcctacatgc tgttagaaga
     2701 cttttgtttc cctaataata caaaaaatag tcggtcaaca cttaagtgtg aagtcgtaca
     2761 ccacagcgtt tctatactta tatgatacca ctttttcaaa aaaaatcaag aggaaagtgc
     2821 aattttttga aaaggatttc agatttttcg caaacgatcg atagcttcct ttctttgagc
     2881 caaagcccgt tcatatttac cagtatcttc tgcttggaaa tagtgatgat tacgaatttt
     2941 ttctggcaga tagtcttgct tgatccaatt tccaggatag ttgtgtggat agagatagtc
     3001 ttgggcattc cccagttcct tgcttccact gtagtgccca tcacgcaggt gtcgcggaat
     3061 aggcaagtgc cctgatgttt tgaggtcagc aagtgcctta tccatagcta cataggctga
     3121 gttggatttt ggagaaaggg ccaaatcaat cacgacattg gcaatgagaa tgcgggcttc
     3181 ggggaaacca atcctttgtg cagcatccag agcagtcacg gtatgaatct gggcctcagg
     3241 attggctaag ccaatatctt cataggcgat aacagtcaag cgacgagcga gactaggcag
     3301 atccccagcc tcaatcaagc gggcagcata gtggagactg gcatccacat ctgagccacg
     3361 gatagacttt tgcagggcag atagaacatc atagtgaccg tctccatcct tgtccatagt
     3421 gatgtagctt ctctgaagac tattttccat gatgtctaag gtgatgtggc gaatgccctc
     3481 gtcattctca ggggtagaga gaacagccaa gtccagtgag ttaaaggcag agcgaaggtc
     3541 tccgtttgta gaggttgcga tgaaatccag cgcatcctca tctagttcta ttggaaaatc
     3601 aaaaccacgt tcagggttac ttagagctat ctgcagggcc tctttgacgt cttggttaga
     3661 cagaggttcc aactcgaaaa tttgaacacg gctacgaatg gcaggagtga cagagaagaa
     3721 aggattttca gtcgttgctc caatcatgat gaccagtcca ctttccaaga gaggcaagag
     3781 gaagtcttgc ttggtcttat ctagtcgatg aatttcgtct agcaatagga cgagaccacc
     3841 agaaaattta gcttcttccg agatttcttg cagtcgcttt ttactatcaa ctgtcgcatt
     3901 gaaagttcga aaggcatact tggtcgttcc agcgatggca gaggcaatac tggttttgcc
     3961 gattccagga gggccatata gaatcatgga ggacaggcgg ttggcttcca ccatgcggcg
     4021 gatgattttt ccaggtccga ccagatgctc ctgaccgatg acctggtcga tggttttagg
     4081 gcgcatgcga agcgcgagat tgtctggcat agcagtcctt tctaacgtgg atttgagtag
     4141 aatgactcat ctactatatc ttactatgtc cattctagcc tattagttgt gatatttcaa
     4201 tggttttgta ataatcaggg agtgagatag aatctttttt actatttaat ttaatgagga
     4261 gaggtatcag catgagagat ttgattttcc ttaaagctca aaataggata gttgagccta
     4321 aagaagtgga agtgctgact tgagaaataa tattgctgaa tgtcattgta tgaactataa
     4381 tgaaaagaga ggtgataagc aatggaaatg atggaccaag tcaggaaatt ttgatttt
//
LOCUS       DAVBEM010000084         4331 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVBEM010000084 DAVBEM010000000
VERSION     DAVBEM010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4331
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.084"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            <1..1261
                     /locus_tag="VQ548_002041"
     rRNA            <1..1261
                     /locus_tag="VQ548_002041"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1313..1385
                     /locus_tag="VQ548_002042"
     tRNA            1313..1385
                     /locus_tag="VQ548_002042"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1346..1348,aa:Ala,seq:tgc)
     gene            1510..>4331
                     /locus_tag="VQ548_002043"
     rRNA            1510..>4331
                     /locus_tag="VQ548_002043"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1191 a          901 c         1293 g          946 t
ORIGIN      
        1 atacatagcc gacctgagag ggtgatcggc cacactggga ctgagacacg gcccagactc
       61 ctacgggagg cagcagtagg gaatcttcgg caatggacgg aagtctgacc gagcaacgcc
      121 gcgtgagtga agaaggtttt cggatcgtaa agctctgttg taagagaaga acgagtgtga
      181 gagtggaaag ttcacactgt gacggtatct taccagaaag ggacggctaa ctacgtgcca
      241 gcagccgcgg taatacgtag gtcccgagcg ttgtccggat ttattgggcg taaagcgagc
      301 gcaggcggtt agataagtct gaagttaaag gctgtggctt aaccatagta ggctttggaa
      361 actgtttaac ttgagtgcaa gaggggagag tggaattcca tgtgtagcgg tgaaatgcgt
      421 agatatatgg aggaacaccg gtggcgaaag cggctctctg gcttgtaact gacgctgagg
      481 ctcgaaagcg tggggagcaa acaggattag ataccctggt agtccacgct gtaaacgatg
      541 agtgctaggt gttagaccct ttccggggtt tagtgccgta gctaacgcat taagcactcc
      601 gcctggggag tacgaccgca aggttgaaac tcaaaggaat tgacgggggc ccgcacaagc
      661 ggtggagcat gtggtttaat tcgaagcaac gcgaagaacc ttaccaggtc ttgacatccc
      721 tctgaccgct ctagagatag agttttcctt cgggacagag gtgacaggtg gtgcatggtt
      781 gtcgtcagct cgtgtcgtga gatgttgggt taagtcccgc aacgagcgca acccctattg
      841 ttagttgcca tcatttagtt gggcactcta gcgagactgc cggtaataaa ccggaggaag
      901 gtggggatga cgtcaaatca tcatgcccct tatgacctgg gctacacacg tgctacaatg
      961 gctggtacaa cgagtcgcaa gccggtgacg gcaagctaat ctcttaaagc cagtctcagt
     1021 tcggattgta ggctgcaact cgcctacatg aagtcggaat cgctagtaat cgcggatcag
     1081 cacgccgcgg tgaatacgtt cccgggcctt gtacacaccg cccgtcacac cacgagagtt
     1141 tgtaacaccc gaagtcggtg aggtaaccgt aaggagccag ccgcctaagg tgggatagat
     1201 gattggggtg aagtcgtaac aaggtagccg tatcggaagg tgcggctgga tcacctcctt
     1261 tctaaggata aggaactgcg cattggtctt gtttagtctt gagaggtctt gtggggcctt
     1321 agctcagctg ggagagcgcc tgctttgcac gcaggaggtc agcggttcga tcccgctagg
     1381 ctccattggt gagagatcac caagtaatgc acattgaaaa ttgaatatct atatcaaata
     1441 gtaacaagaa aataaaccga aaacgctgta gtattaataa gagtttatga ctgaaaggtc
     1501 agaaaataag gttaagttaa taagggcgca cggtggatgc cttggcacta ggagccgacg
     1561 aaggacgtga caaacgacga tatgccttgg gtagctgtaa gtaagcgatg atccagggat
     1621 ttccgaatgg gggaacccaa caggtagtac ctgttaccca catctgttaa ggatgtgagg
     1681 aggaagacgc agtgaactga aacatctaag tagctgcagg aagagaaagc aaaagcgatt
     1741 gccttagtag cggcgagcga aacggcagga gggcaaaccg aagagtttac tcttcggggt
     1801 tgtaggactg caatgtggac tcaaagatta tagaagaatg atttgggaag atcagccaaa
     1861 gagagtaata gcctcgtatt taaaatagtc tttgtaccta gcagtatcct gagtacggcg
     1921 ggacacgtga aatcccgtcg gaatctggga ggaccatctc ccaaccctaa atactcccta
     1981 gtgaccgata gtgaaccagt accgtgaggg aaaggtgaaa agcaccccgg gaggggagtg
     2041 aaatagaacc tgaaaccgtg tgcctacaac aagttcgagc ccgttaatgg gtgagagcgt
     2101 gccttttgta gaatgaaccg gcgagttacg ttatgatgcg aggttaagtt gaagagacgg
     2161 agccgtaggg aaaccgagtc tgaatagggc gccttagtat catgacgtag acccgaaacc
     2221 atgtgaccta cccatgagca ggttgaaggt gcggtaagac gcactggagg accgaaccag
     2281 ggcacgttga aaagtgcttg gatgacttgt gggtagcgga gaaattccaa acgaacttgg
     2341 agatagctgg ttctctccga aatagcttta gggctagcgt cgacattaga gattcttgga
     2401 ggtagagcac tgtttgggtg aggggtccat cccggattac caatctcaga taaactccga
     2461 atgccaatga attatggtcg gcagtcagac tgcgagtgct aagatccgta gtcgaaaggg
     2521 aaacagccca gaccaccagc taaggtccca aaataattgt taagtggaaa aggatgtggg
     2581 gttgcacaga caactaggat gttagcttag aagcagctat tcattcaaag agtgcgtaat
     2641 agctcactag tcgagtgacc ctgcgccgaa aatgtaccgg ggctaaaaca atttaccgaa
     2701 gctgtggata cctttatagg tatggtagga gagcgttcta tgtgtgatga aggtataccg
     2761 tgaggagtgc tggaacgcat agaagtgaga atgccggtat gagtagcgaa agacaggtga
     2821 gaatcctgtc caccgtaaga ctaaggtttc caggggaagg ctcgtccgcc ctgggttagt
     2881 cgggacctaa ggagagaccg aaaggtgtat ccgatggaca acaggttgat attcctgtac
     2941 tagagtatgt agtgatggag ggacgcagta ggctaactaa agcagacgat tggaagagtc
     3001 tgtctaagca gtgaggtgtg atatgagtca aatgcttata tctgtaacat tgagctgtga
     3061 tggggagcga agtttagtag cgaagttagt gacgtcacac tgccaagaaa agcttctagc
     3121 gtttaaacat actctacccg taccgcaaac cgacacaggt agtcgaggcg agtagcctca
     3181 ggtgagcgag agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa
     3241 ggggtgctga ctttaagtca gccgcagtga ataggcccaa gcaactgttt atcaaaaaca
     3301 cagctctctg ctaaatcgta agatgatgta tagggggtga cgcctgcccg gtgctggaag
     3361 gttaagagga gtgcttagcg taagcgaagg tatgaattga agccccagta aacggcggcc
     3421 gtaactataa cggtcctaag gtagcgaaat tccttgtcgg gtaagttccg acccgcacga
     3481 aaggcgtaat gatttgggca ctgtctcaac gagagactcg gtgaaatttt agtacctgtg
     3541 aagatgcagg ttacccgcga caggacggaa agaccccatg gagctttact gcagtttgat
     3601 attgagtgtc tgtaccacat gtacaggata ggtaggagtc taagagatcg ggacgccagt
     3661 ttcgaaggag acgctgttgg gatactaccc ttgtgttatg gccactctaa cccagatagg
     3721 tgatccctat cggagacagt gtctgacggg cagtttgact ggggcggtcg cctcctaaaa
     3781 ggtaacggag gcgcccaaag gttccctcag aatggttgga aatcattcgc agagtgtaaa
     3841 ggtataaggg agcttgactg cgagagctac aactcgagca gggacgaaag tcgggcttag
     3901 tgatccggtg gttccgtatg gaagggccat cgctcaacgg ataaaagcta ccctggggat
     3961 aacaggctta tctcccccaa gagttcacat cgacggggag gtttggcacc tcgatgtcgg
     4021 ctcgtcgcat cctggggctg tagtcggtcc caagggttgg gctgttcgcc cattaaagcg
     4081 gcacgcgagc tgggttcaga acgtcgtgag acagttcggt ccctatccgt cgcgggcgta
     4141 ggaaatttga gaggatctgc tcctagtacg agaggaccag agtggactta ccgctggtgt
     4201 accagttgtc ttgccaaagg catcgctggg tagctatgta gggaagggat aaacgctgaa
     4261 agcatctaag tgtgaaaccc acctcaagat gagatttccc atgattatat atcagtaaga
     4321 gccctgagag a
//
LOCUS       DAVBEM010000085         4328 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVBEM010000085 DAVBEM010000000
VERSION     DAVBEM010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4328
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.085"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(<1..641)
                     /locus_tag="VQ548_002044"
     CDS             complement(<1..641)
                     /locus_tag="VQ548_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET2654830.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKL"
     gene            complement(750..1268)
                     /locus_tag="VQ548_002045"
     CDS             complement(750..1268)
                     /locus_tag="VQ548_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HET2654831.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(1495..2364)
                     /gene="rsmI"
                     /locus_tag="VQ548_002046"
     CDS             complement(1495..2364)
                     /gene="rsmI"
                     /locus_tag="VQ548_002046"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HET2654832.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGTSAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2367..2684)
                     /gene="yabA"
                     /locus_tag="VQ548_002047"
     CDS             complement(2367..2684)
                     /gene="yabA"
                     /locus_tag="VQ548_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HET2654833.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(2724..3614)
                     /locus_tag="VQ548_002048"
     CDS             complement(2724..3614)
                     /locus_tag="VQ548_002048"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HET2654834.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(3611..4249)
                     /locus_tag="VQ548_002049"
     CDS             complement(3611..4249)
                     /locus_tag="VQ548_002049"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HET2654835.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
BASE COUNT         1200 a          982 c          691 g         1455 t
ORIGIN      
        1 tctagttttg caggaagtct aatgtaattc tcaagctgtg agttcattat gatttgtaaa
       61 tccgatatat cttcagcagc taaaaacaca ttttgaaatg ttccaagtcc gttttcacca
      121 aaactatatt ctctcttact atacttactc ttattattct ctatatagtt agagtcaagg
      181 ttcttaacct cttgaagttc attttcttta cttctgaggt taaaatcttt tacttctgaa
      241 gttaagtttt ttgacttctg taagtcattt tcttttacct gaaatatact cataaagtct
      301 ttaacataaa tgatgttcgg cttaccaagt ccaagcctta ctctttcgat cagtcctatt
      361 ccttttttta catcaagctc atctaatgtt tttatggcag ttggctttga gatatttctt
      421 cttttcataa tttcttcgac agtaaaatag ataaatactc tgccttcctt gtctatccag
      481 ttattcttaa atgacattcc tgtctgttta agaagtatgg aataaaggat aattgcttct
      541 gctgataagc cccgaaattc ttctctatca actaatatct ccggtacttt taagaagtta
      601 aatctttccg cttctctgtt ataaaaatat tcaaagtcca tgcaagatca cctcccttct
      661 taaaaatttg caaagaaaaa gacgatagtt tttcttctat cgcctttggt aaccattttt
      721 atgaaatttt ttaaagttaa aaatataatt tataatacta tcttcttcca ttttctgatt
      781 ttagttctga aagttccaaa aggtgcaacc gtatttacat gaataaactt atacacttcc
      841 caagtcgctg ttttagtcgc ttcatcagcc cactttctca tatgcggttc aaataattct
      901 tcctcactca acgaatcaat cattgcagag atagaattaa tattttcatt taattttgct
      961 ttcaactctt gcagagataa atgagcgtag gtatctgtga accactgata taattcacca
     1021 agttgattcc atttaaattt atccgatggt gtttttactt gaagcccctt tctttcatct
     1081 tcttcccatt taagaaccaa gttggtccaa ccaacctgat aagcaaggtt ttctgctgga
     1141 gttctgtcaa cttcatcagc tctcttatct tttaaatttt ctggaatatt atcaaattct
     1201 aaaatatatt tctcaaatgt tttctctatc tcagctttta gttcttcttt attttcgtat
     1261 gttcgcaaaa aatcaccttc tttctgattt atcaatcctt tgatttaaaa tgaccttatt
     1321 tttctattta taccttctaa gaacgctata actgctgctc caaacatcgg tattccgtat
     1381 gggcttaata aaaaacttaa taccaaagct tctataccaa gtgatacatc tttatattat
     1441 catcactaat taagttaaac agaaacagac agaattatta catcctgtct ccctttattg
     1501 tttttcttcc caatcgtggt aggcagcgta gagttgactc ttattccact ggtaaatctt
     1561 agctacttcc ttaatagctt gatttttctt catgccttgc tggatacggg cttggatttc
     1621 taagaacaag tcctcctcgt ctttttcctc cacatcctga ctggcacctt caacaataag
     1681 aaggcattcg cccttgagtg gcgtttcagc gatgctttcc agtaattcag aaattgtacc
     1741 tcgttggtat tcttcataga ttttggtcaa ttccctgacc aaaacaaccg agcggtcacc
     1801 gtagacttct aacatatttt ccaacgtgtc tgctacacga tgaggtgatt cataaaaaat
     1861 ctgtgtttca ggataatctt ttttagagcc aaaaaattgc ttctgttgac ctgattttct
     1921 cggtaaaaaa ccgtaaaaga tatgtggctg tggcgctaaa ccactggcaa tcaaggcaga
     1981 aattcctgca gaggtacctg gaacagtcac aactgcaatt tcttcctcaa tagctgcctt
     2041 aactaaatca tgaccagggt ctgaaatgct aggcaaaccg gcatcagaga cctgagcaat
     2101 actttgccct gctttcaaga aaccaatcaa atcaggaatt ttttccttgg cattgtgctc
     2161 atgaaaactg atctgcttgg tggaaatgtc aaaatgcttg agcaaaagcc ctgtattgcg
     2221 cgtatcctca gcagcaatcc agtccacttc tttcaaggtc tggatagcac gaaaagtcat
     2281 atcatctaga ttgccaatcg gcgttgccac tagatacagc ttgccatagg gagactgccc
     2341 cttaaaactt ttttgaattt gcatgcttac tccctgtata acaactcatc acagaacata
     2401 cattcttcgt cctgctctcg acgttgtcca taaaaatcat tacatacgtg aaatccatca
     2461 cggtaaatac gacggacact ttcgcgaaca tgcttggcct tgacgggagc gtctgcttcc
     2521 acctcaccca agcgttctcg caacttacta ttttccaagc gaagagctgt attttcttct
     2581 accaagctct tgagattttt cttgatggct tccacatcgg ctaaagttac caataattgt
     2641 tgggaaaaat catccagcgc gtcaaataat tcttttttgt ccataaaaca gccctttcct
     2701 ttctttatca ttcatttttg agtttatatt tctttcaaga ccagatattc catggcattt
     2761 tgaaagctga cattagcttg ccacattttt ctagcttcta gtaaatcttg tagaatcact
     2821 cttactctta cctgcaagag gtcctgccca cagagaactt caagaatccg taaaacctga
     2881 tcctgttttt ccttatcatc tgccaagttg gctaatttgg caacctgtag ataactttct
     2941 tttttcttag ctactaacca agtcagcagg cgttcacttt catcgaccaa ggtccaaaaa
     3001 cttgcctgat tagccaactt ttctgcttca gctcgcgatt gactaaactt agctaaaaga
     3061 gtcgcttttt tcttaacaag tcccatttgt tctaagagta agataagttt ttcttcttgc
     3121 tttttaaagt ggaagatctg agtccgactt cggattgtcg gtaacatctt ttcctcatcg
     3181 ctagtcaaga agaaaatata aacttcactc tggggttctt cgatgacctt gagcagagaa
     3241 ttggctgcgt tgggatgcat tttatccgct tgctcgatga taaagacctg ttgctggctt
     3301 tcaatccctg cttgagaaaa ctgtcccacc aattcccgaa tacgttctgt cttgatgacc
     3361 tgattgactg gcttaatcaa ggtgacatct ggaaactctt cctgttcaat cagcttgcaa
     3421 cttcggcatt tctcacatgg taagacgcca actttatccg tacaaaagag gctcttagct
     3481 aaaaattgcg ccatttccaa gcttccaaag aaacctgaaa agagataggc gtgattgagc
     3541 tggtcttgtt ctaagatacg gacaaaacgg tcaaactgag ctggttgcca agcctttagt
     3601 tgatcttgtt tcatttggcc aagcccattc cgtcaaacaa gacagccttg gtagtttcca
     3661 caacttgctc caaagggaga ctagcatcaa tcttgacaat gcgatttccc tctttatcca
     3721 gaagagaaag gtagccttga cgaacttttt tatgcaagtc caacccttcc aaatccaaac
     3781 gattaacctc gcggtcacta ttagcagcaa tacgagccag cccttcttcc acctcgatgt
     3841 caaaatagag tgtcaaatcg ggtttgaggc catctgtcgc aaactgattg agccagtcaa
     3901 tggcttcaat atctaagcca cgaccaaatc cctgataggc aacagaacta tcgataaaac
     3961 gatccatgat gaccaacttg ccagcttcaa gggctggaag aactttttcc accaaatgct
     4021 gtctgcgact ggcaatatag agaagtagct ctgttttagc atccatctga gtatgacttg
     4081 gatccaaaat cacttcccga atcttctccc caatcaagac tccgccaggt tcacgggtcg
     4141 tcagcacctt tactcctttt tcctctaaaa ttggtagcag agcctctaaa acactggtct
     4201 tgcctgctcc ctctggtccc tcaagagaga ctaaaaatcc ttttgacatg tctaactcat
     4261 ttctttttta ctacttctat tctatcaaaa aaataggggt ttgtgacaat ctttttgtct
     4321 tctcattt
//
LOCUS       DAVBEM010000086         4255 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVBEM010000086 DAVBEM010000000
VERSION     DAVBEM010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4255
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.086"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(9..1298)
                     /locus_tag="VQ548_002050"
     CDS             complement(9..1298)
                     /locus_tag="VQ548_002050"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HET2654836.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(1376..2623)
                     /locus_tag="VQ548_002051"
     CDS             complement(1376..2623)
                     /locus_tag="VQ548_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HET2654837.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGVSIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVSVIISSLTGNDYFGKQSLPRLMMWETVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(2814..3664)
                     /gene="rgg"
                     /locus_tag="VQ548_002052"
                     /pseudo
     CDS             complement(2814..3664)
                     /gene="rgg"
                     /locus_tag="VQ548_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398326.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes.; frameshifted;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
     gene            3788..4129
                     /locus_tag="VQ548_002053"
     CDS             3788..4129
                     /locus_tag="VQ548_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET2654838.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
BASE COUNT         1352 a          891 c          830 g         1182 t
ORIGIN      
        1 tttgattttt attgagtata aaatcctagt ttttcaaaga tttctgagaa gttttggctg
       61 attgtctcaa gtgacacttg cacttcttct cgggtttggt tgttcttgac cgtcacttgt
      121 ccgctttcga cttcgctctc tcctagggtg atgagggtct tagccgcaaa gacatcggct
      181 gacttgaact gagcttttag tttacggttg aggtaatcac gctctgcttt gaaaccttgt
      241 tggcgaagag cctgtaccaa ttccaaggcc ttgatatttg ccccttcgcc caagactgcg
      301 atatagacat ctagggcgtt ttcgataggg agggtcacac cttgcttttc aaggatgaga
      361 agcaggcgct ctacaccaag tccaaaacca aatccagcag tttcagggcc tccaaagtaa
      421 gcaaccaaac catcgtagcg accacccgca cagacggtca ggtcattgcc ctcaatctct
      481 gtgataaact cgaaaatggt gtggttgtag tagtccagac cacgcaccat attggtatcg
      541 atgatgtaat ctactccaag attttccaac atctgacgca cagcatcaaa atgagcttgg
      601 ctttcttcat caagaaagtc caagatagac ggcgcattct ctactgccac cttgtcttct
      661 ttttccttag agtccaagac acgaagagga ttttcctcca agcgacgttg gctatcctta
      721 gacaaggtct ccttgagcgg tgtcaaatag tcaatcaagg cttggcggta ggctgcacgg
      781 ctctcaggat ttccaagagt gttgaggtgc aatttgacac cttgaatacc gatttccttc
      841 aaaaaatggg ctgccatagc gattgtttcc acatcggtag ctggattgct agagccaaaa
      901 cactcaacac caatctggtg gaattggcgc aagcgccctg cctgtggacg ctcataacgg
      961 aacataggtc ccatgtagta gaacttgctt ggcttttgca cttctggggc gaaaagttta
     1021 ttttccacat aggaacggac aacgggtgca gttccttctg gacggagggt aatatgacgg
     1081 tcacccttgt cataaaaatc gtacatttcc ttggttacga tatccgttgt atctccgaca
     1141 gagcgactga taacctcgta atgctcaaaa ataggcgtgc gcacttctgc atagttgtag
     1201 cgtttgaaaa tctcacgggc aaagccctca acgtactgcc acttagcaga ctcagcaggt
     1261 aaaatatcct gcgttccttt tggtttttgt aatttcatag ggaatcctct ttaaacttaa
     1321 tagtcttatt ttaccataaa tagagggatt aaaacagtaa gaaaaaaatt aggatttaga
     1381 tatcattttt gagattaaga attgtcaaaa aaatagctag caaggaaaga ccaacaaata
     1441 gcatccaagt caactgtata ttccatacgg ctactagtga aaaacaagct gttcccacag
     1501 gtatggataa ggtaaacaat agacctaaaa aattactagt acgagctaga acctctggag
     1561 ctagattttt catgagcatg gcactaatct ttggttgaac tttaccagac acatacagag
     1621 taaagaagag aaatagcaaa ccaagcacga cttgattgaa taaattagcc aaaccaacta
     1681 gactaagtcc tacggtctcc cacatcatca atctaggcaa ggactgcttc ccaaaataat
     1741 cattgcccgt aaggctactg atgatgactg atactaaaac acagaattga ttgataaata
     1801 gtgcctctgt ataagaaaaa ttcaagagag aatggctcaa aaagaagata ttataaattc
     1861 cacccaaagc gccacccaag gaattaataa gcaagacagc aaagagcata aaaccaaagt
     1921 ttttctgtcc acttttaaga aaaacgagac gtaaatttcg gtaaattgtt aggaactggt
     1981 ctttgataga aagcttctca ttttttaagt tttcaccatc agcagatgac attgacaggc
     2041 tcaatttgct ttttcctaaa aagaggatag tggctgatac taggaaaaag caggcattga
     2101 ttcccgcaac gagagaaaaa ttgttgaccg atagagctaa gagccagact ccgaaagctt
     2161 gaccaccaat agctgaaata taggtgatga actgtgaaaa agaataagcc tccatcagat
     2221 catcttcagc tactttttcc ttaataagag gcatacgcag gccacctgca aaatcactga
     2281 tgatatcact aatgacattg atcaaacaca ggctagaaaa ggcaaagaga ctagcttgct
     2341 gaacaactag ggctgctaga aaaaatagaa ccgcctgaaa caaaccgcta tagaccatcc
     2401 atttgacctt gtccctcgtg taatctgccc gaatccctgc aaaaactgta aagagggtcg
     2461 gaagaatcat gacaatattc gccatagcaa cagcaaaaga tgcttgtgac aaggtcgatg
     2521 catagacgat aaagaccagg ttgaaaatcg aaacaccaaa agcattgaag aagcgtgata
     2581 aagtcaaaat tctataagct ggatttctaa acaatagttt catagataat ctccctcctt
     2641 gttctaagtt ctacatcaag aatagcttta gtatagcact tatgaatttg cgaaacgatt
     2701 cttttgaata tatgcaacaa acaaaatgag caaaaaaacg atagaacttt tgtaatgacc
     2761 tgagagaggg caacagttct atcgcttcaa attttttctt ggtttgcaga tattcaagaa
     2821 tcgggagttt ttctatagta ttcggcagat ttattacagc caagcatctc aaaaatacgg
     2881 acagcatcct ccatcttttt ctggccttcc ttgactctac cttgcttgct atcaaggaga
     2941 ccttctgccc acagataaac aattcggaaa taggtctcat tttccttgta gaaatgctct
     3001 tcgataacac gtttaaaata ataggcattg gtaaattctt cacactcaat actagctaaa
     3061 aagccattca atagtatagt atgaaaaagg tttcgattgc cagacatttc cattagaaaa
     3121 tcggatttac gtaccatttc tcgtacatat ctagtaaaaa gagaaacaga taaaaatgga
     3181 gaactgactg aaaataaatt gagttcatag attccccaga tctcggtaga aaacaaataa
     3241 tcatgaagga cttttccttc ctctgctgtt aagtctaccc tttcatctat gctcttcata
     3301 taagacttga taataatggc atttagaata tgtttctgtt tgttgtgaga atgggcatgc
     3361 ttttatactc cctgcgatat aagtcctcaa gaggtgctat attctttggt tccaagacat
     3421 ctgtaatttc ttttctcaac tcagaatctg tatcatactg gaaacctctt gccagaaaga
     3481 ggatctcctc cacactggca gatatatttt ccagagcaaa tagaaacttt tccaccgaaa
     3541 gctcactctg acctgtttca aaacgggaca acatagacgg cgaaaattgt cctccggttg
     3601 cttgtctcag tgagatattt cttgactctc gtaattgtct aaagactttt ccaatctgct
     3661 ccatagactt ccccttgatt ccgtattttc ttcattttat catatttttc agaaaattca
     3721 tcaaaaactt gccaaattgt cagaattatg agaaaataga ggatatttat cacgtggagg
     3781 gactgctatg agagacgata tcaaaatcaa tgaccgtgct ttggccttgc aagaccaaat
     3841 tatcgaaaaa ctagagaaag tttttgatac agatgtggaa ttggatgttt acaatctagg
     3901 tctgatttat gaaatcaatc tggatgaaac ggggctctgc aagattgtca tgaccttcac
     3961 cgatactgcc tgtgattgcg ccgaaagcct gcctattgaa atcgtggcag gtctgaaaca
     4021 aatcgagggt atcaaagata tcaaggttga agttacctgg tcgcctgctt ggaaaatcac
     4081 acgaatcagt cgctatggcc gtattgccct tggactacca cctcgttaag cagaccaatc
     4141 acttttaaag atgaaaaaag caagccgaaa atggcttgct ttttgatact caatgaaaat
     4201 caaagggcaa actagaaaac tagccgcagg ttgctcaaaa cactgttttg aagtt
//
LOCUS       DAVBEM010000087         4116 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVBEM010000087 DAVBEM010000000
VERSION     DAVBEM010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4116
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.087"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            <1..776
                     /locus_tag="VQ548_002054"
     CDS             <1..776
                     /locus_tag="VQ548_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654839.1"
                     /translation="DYSIVEEKLDWQSKLSKIYPNVEFIKIEKLKLILLCKYRNQIID
                     LEDDKKRLLLLKLLYLTSKQFCYDEFKGAKFGCMSFFSHYQGYMSRLDSLDSDKFVSV
                     KQRIVSSISKLVEQYSDHIINLDRTLVDSLSDTLENQLFDDWDYILSEITTYSELLAK
                     SGLLYNSLDYKIDNVKKEVAKLSDFHQSLFKIEGFSDFFDSWQFQRYRSLVNQVYEIF
                     SMLQVSSVERTVLCGALSTIVFSKSNFNYQAFFEYLKDT"
     gene            805..1713
                     /locus_tag="VQ548_002055"
     CDS             805..1713
                     /locus_tag="VQ548_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654840.1"
                     /translation="MDYVDVILDEYGSVFLIKDHIKLKINNLELYRYFSSFGMSHLQF
                     RKEELPGKLKQFDFEKNKSDSYFSKKSSLIDFIKRNYFYDIKLYSDNPKNPIESWKNK
                     TEKIKIAKSTEILWSEVANFSSISKSPYYCLLYNLKNTENYILIISKTYFSAIQKMVS
                     YNLNNYFELEDVCCKSIVSKRELIENSININKSKMKLLNVCEGSKGYTRRVFKYNNIF
                     VGQLEFHSNIIFSEIALNELSIVKLLDSVESVLSEQLFGKLNWDNLFVVLSDDFNDYL
                     DINESQKYYSNGSLRGLELGIFMGGV"
     gene            1715..3613
                     /locus_tag="VQ548_002056"
     CDS             1715..3613
                     /locus_tag="VQ548_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HET2654841.1"
                     /translation="MRIIEIVDVEDQLLQLLSAHTNIDIRAQELSTLDPDSKVDLIIY
                     LKSRRDIENINNIIIKSPNRNIIVIISAFDIIYALYFPKSTFRPCLNCLLLKLKDNNP
                     EHNLLLFLKYGTLPSKHFNLDNRLKSNLILFNEKLDPKVEEYSIEGVNTTNFTFHFSC
                     SCENSGYDMSERMADILLGEGKKLSPKNYRLKKSEHLFDFTRYLDRNFGFFHHSYDEK
                     ISEYAPLHAVEINVDAGYESGWGRTFMTEAATKSAFLESLERYCNSRNRRYKKLIRGC
                     FSDLSKKYNTLNPVDFCLSNKEYRDSSYKFHDFDSEKNYDWIFGKNITTGKICLLPSQ
                     LVFYKDFSKSEENERFVYETSNGCALGSSIEEAIFYGILEIIERDNFLLTWYLKEEVK
                     QLSWESLPSRLRIINERLKEDNCELKLFNITKEVGIPVIWALYINHNENASIRSFSAA
                     GCHINPLSAIESAIFEVITSVPTFERLIEVRNKESFIEEIQNNFSLIRDIDDHILYHA
                     HADYKNKMPFLFKNNYSEYQNEFDENRIFNTYSHATLTSDLQALIKIIEKKFGDIYVV
                     NISDKVSEKFGLYCVKVLIPGLLNMSFGHSNRRVNIERIKNYVDYRGGNVNSITLNSI
                     NHLPHPFP"
     gene            3637..>4116
                     /locus_tag="VQ548_002057"
     CDS             3637..>4116
                     /locus_tag="VQ548_002057"
                     /inference="COORDINATES: protein motif:HMM:NF025394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="HET2654842.1"
                     /translation="MKRDWKSKHLFYHDVQQFDKLVIYLSKFMDKLVNQNQIEKYFYI
                     RYWEGGPHIRLRYLVRDTQNFETIDSMINKYAYKFWENNPPMKLLNKTDYKKIYNESI
                     DNNGKMDRKLRKNATIENIAYIPEIERYGGEEALIVSEDLFCICSQVSTALLNVVDNY
                     "
BASE COUNT         1539 a          443 c          712 g         1422 t
ORIGIN      
        1 cagattactc aatagtggaa gaaaaattag attggcaaag taaattatct aaaatttatc
       61 cgaatgttga atttataaaa attgaaaaat taaaattgat tttgttgtgt aaatatagaa
      121 atcaaattat tgacttagag gatgataaaa aaagattgtt actattgaaa ttattatatt
      181 tgacttcaaa gcaattttgc tatgatgaat ttaaaggagc gaaatttgga tgtatgtcat
      241 ttttttcaca ttatcaaggt tatatgagca gattagattc actcgactca gataaatttg
      301 tttcggttaa acagaggatt gtttcctcta tttctaaatt agttgagcaa tattcagatc
      361 atattataaa tctggataga actttagttg attctctaag tgataccctt gagaatcagc
      421 tatttgatga ttgggattat atattaagcg aaataactac atatagcgaa ttattagcaa
      481 aatcaggatt gttatataat tcgctagact ataagattga taatgtaaaa aaagaagtgg
      541 ccaagctaag tgactttcac caatctttat ttaaaattga aggattttca gatttttttg
      601 atagttggca atttcaaaga tataggtctc tcgtgaacca agtttatgaa attttttcaa
      661 tgttacaagt aagtagtgta gaaagaactg tgttgtgcgg agctctaagt actattgtct
      721 ttagtaagtc aaattttaac tatcaagctt tttttgagta tctaaaagat acgtagaatt
      781 cgattttaaa ggaggctgaa atatatggat tatgtagatg taatattgga tgagtatggg
      841 agtgtttttc tgataaagga tcacataaaa ctaaaaatta ataatctaga actatatcgg
      901 tattttagta gctttggaat gagtcatctt caatttagaa aagaagagct tccaggaaaa
      961 ttaaagcagt ttgattttga aaaaaataaa agtgacagtt atttttctaa gaaaagtagt
     1021 ctgattgatt ttattaagag aaattatttt tatgatatta agttatattc tgataatccg
     1081 aaaaatccga tagagtcttg gaaaaataag acagaaaaaa ttaagattgc taaaagtaca
     1141 gaaattcttt ggagtgaagt agcaaatttt tcgtcaattt ctaaatctcc ttactattgc
     1201 ttgttatata atttaaagaa tactgaaaat tacatattga taatcagtaa gacatatttt
     1261 tcagccatcc aaaaaatggt ttcgtataat ctaaataatt attttgaatt agaagatgtt
     1321 tgttgtaaaa gcatagtgag caagcgagaa ttgatagaaa attcaattaa tattaacaaa
     1381 agcaaaatga aactgctaaa tgtttgcgaa ggtagtaaag gttacacaag aagagtattt
     1441 aagtacaata atatttttgt gggacaattg gaatttcact ctaacataat cttttcagaa
     1501 attgctttaa atgaattaag tattgttaag cttttagatt ctgttgaaag tgttttatct
     1561 gagcaactat ttggaaaatt aaattgggat aatttatttg ttgttttatc agatgatttt
     1621 aatgattatc tggatataaa tgaatctcaa aaatactact caaatggttc tttgagagga
     1681 ctggagcttg gaatctttat gggaggggtt taaaatgaga ataattgaaa ttgttgatgt
     1741 tgaggaccaa cttttacaac ttttaagtgc acataccaat attgatatta gagcacaaga
     1801 gttatcaaca cttgacccag attcaaaagt tgatttgatc atatacttga aatctcgacg
     1861 tgatattgaa aacataaata atattattat taaatcacct aacaggaata tcattgttat
     1921 aataagtgct tttgatatta tatatgcatt gtattttcca aaatcaacat ttagaccttg
     1981 tttgaactgt ctattattaa aacttaaaga taacaaccct gagcataatc tattattatt
     2041 cctgaaatac ggaacattac ctagtaaaca ttttaatctt gataataggt taaaatcaaa
     2101 tttaatacta tttaatgaga agttagaccc taaggtagag gagtatagta ttgagggggt
     2161 aaatactaca aattttactt tccattttag ttgtagctgt gaaaatagtg gttacgatat
     2221 gtcggaaaga atggcagata ttctacttgg tgaaggaaaa aaattatctc ctaaaaatta
     2281 tcgtttaaaa aagagtgagc atctattcga ttttactaga tatctagata gaaattttgg
     2341 attttttcat cattcatatg atgaaaaaat ctccgaatat gcgcctctcc atgcagtaga
     2401 gattaatgtt gatgctggtt acgagtcagg ctggggaagg acttttatga cagaggctgc
     2461 aacaaaatct gcttttttag agtcattaga gagatactgc aactctagaa atagacgcta
     2521 taaaaaatta attagagggt gtttttctga tttatctaaa aagtacaata cattaaatcc
     2581 tgttgatttt tgtctttcta ataaagaata tagagatagt tcctataaat ttcatgattt
     2641 tgattctgag aaaaattatg attggatatt tggtaaaaat ataactaccg gaaaaatttg
     2701 cttattgccc tcgcaactag tattttataa agactttagt aaaagcgaag aaaatgaaag
     2761 gtttgtttat gaaacatcaa atggatgtgc tttggggagt agtattgagg aagctatttt
     2821 ttatgggatt ttagagatta ttgaaagaga taatttttta cttacatggt atttaaaaga
     2881 agaagtaaaa caattatcat gggaatcttt accatctcgc ctacgtatta ttaatgaaag
     2941 actaaaagaa gataactgtg agctcaaact ttttaatata actaaagaag tgggcatacc
     3001 agtaatttgg gcattgtata taaatcataa tgaaaatgct agtattcgaa gtttttcagc
     3061 tgcaggctgt catattaatc ctttaagtgc aattgaatca gcaatttttg aagtaataac
     3121 ttctgtgcca acttttgaaa gattaattga agttagaaat aaagagtcat ttattgagga
     3181 aattcagaat aatttttctt taatacgaga tattgacgat catatattgt atcatgctca
     3241 tgcggattat aaaaataaaa tgcccttttt atttaaaaat aattatagtg aatatcaaaa
     3301 tgaatttgat gagaatagaa tttttaatac ttattcacat gcaacgctta catcagattt
     3361 acaggcacta ataaaaatta ttgaaaaaaa atttggagat atatatgtag tgaatataag
     3421 tgataaagtt tccgaaaaat ttggacttta ttgtgttaaa gtgttgattc ctggacttct
     3481 taatatgtca tttggacatt caaatcggcg tgtaaatata gagaggataa aaaattatgt
     3541 agattataga gggggaaatg taaatagtat tacattgaat tccataaacc atcttcccca
     3601 tccatttcca taagattata tataaaggaa taataaatga aaagagattg gaaatcaaag
     3661 catttatttt atcatgatgt tcaacaattt gataaattgg taatctattt atcaaaattt
     3721 atggataaat tagttaatca gaatcagatt gaaaaatatt tctatattcg ttattgggaa
     3781 ggggggcctc atattcgatt aagatatttg gtgagggata cacaaaattt tgaaacaatt
     3841 gatagtatga taaataagta tgcttataaa ttttgggaaa ataatcctcc aatgaagtta
     3901 ttaaataaga ccgattataa gaaaatttat aatgagagta ttgataacaa cggaaagatg
     3961 gatagaaaat tgaggaaaaa tgcgactatt gaaaacattg cctatatacc ggaaatagag
     4021 agatatggcg gggaagaagc tctgatagta agcgaagatc tattttgtat ctgtagtcag
     4081 gtttcaactg cgttacttaa tgtggtagat aactat
//
LOCUS       DAVBEM010000088         3299 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVBEM010000088 DAVBEM010000000
VERSION     DAVBEM010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3299
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.088"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(384..1859)
                     /locus_tag="VQ548_002058"
     CDS             complement(384..1859)
                     /locus_tag="VQ548_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HET2654843.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDDSVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            2566..3299
                     /locus_tag="VQ548_002059"
                     /pseudo
     CDS             2566..3299
                     /locus_tag="VQ548_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT         1041 a          705 c          612 g          941 t
ORIGIN      
        1 ataagaaaga cgctcatggc atcgctctta aacttctttc tgaccccaat cgtgaacaat
       61 ttcaacacga taatcggcaa gtagaactaa aaatactgac tagacatatt catcgtctca
      121 agaaaaaaca gtctgattgg aaagtacaat acactcgttg tcttgatatc atctttcctg
      181 agttggataa aatcgttgga aagcattcag aatataccta ccaactcttg acacgctacc
      241 ctaatcctca gaaaaggatt gaggcaggat ttgataagct gatagaaatt aagcgattga
      301 ccgcttctaa ttcaagggct ttttgccgtg ctctaaaatc atcgccaaat catcaaattg
      361 aaataagaaa tagtttagat aaactattga cttttcttat agtttgtctt tctcttaata
      421 acgttgatat gattgacctc tggatcttcc gtcccttgga gggagcaacc acgttccttg
      481 gcgaattgga tatagtcgac aatttctcgt gtaatgcgtt caccaggagc caagatagga
      541 atacctggag ggtaacacat aacaaattct ccacagacct gtccaacaga atcatccaaa
      601 gttaaacttt ttctttctga atagaaggct tcttgcggag acagcactaa ctcgggctga
      661 atatattctc ctgctatcaa atcttttcca tctcttgaat agagtctctt aatatcagcc
      721 agagcaccaa ccaagcgctc gatgtcttgg atgcggtcgc cgatggaaat ataggccaag
      781 atattgccga tatcaccaaa ctcgatctga atgtcgtatt cgtctcgcaa gaggtcataa
      841 acctcgatac ctgttaagcc aataccctga gtgtaaactg acaacttagt tacgtcaaaa
      901 tcgcaaaccg aaacaccgtc tattaactct tttgagtagg catagtagcc accgatagca
      961 ttgatttcat gacgagcgta ctcggatagc tcaatgactt cctcaaacga ctctttacca
     1021 cgaagggcca agttgcgacg tgaaatatcc aaactagcca tcaataagta agaggcagat
     1081 gtagactggg tcaggtttat aatctgacga acgtactcgg gattcatctg ctccccgatt
     1141 aaaagaagcg aactttgtgt caaactccca ccagacttat gcatggaaac tgctgccata
     1201 tcagctcctg catccatagc agaaattgga agtttaccag tgaaatgcaa atgcgctcca
     1261 tgggcttcat ctactaaaac catcatgcca gcttcatgag ccatttctgt caaccccttt
     1321 aggtctgaac agatgccgta gtaagtagga ttgttgatta ggatagcctt agcatctgga
     1381 tggtccttta tggcctgtgc tactcggtca ttttcaagac ctaaagcgat accaatctta
     1441 ggatctacac tcatctcgat atagatggga atggcaccac atagaaccaa cgcattgata
     1501 gcagatttat ggacatttcg tggcagaata atcttatctc ctgccttgca ggttgccaga
     1561 atcatagtct gcaccgatga agttgttcca ccaatcatta gaaaggcatg gctagctcca
     1621 aaagcatctg cagccagctc ctctgcatca cgaataatcg aaataggatg gcctaaatta
     1681 tccaagggtt tcatcgaatt gacatcaatg cctacacatt tttctcctaa gagttcgaca
     1741 agttctggat ttccccgtcc acgcttgtga cctggaacat caaagggaac aatccttttc
     1801 ttgcgtaact tcaccaaggc ctcataaatt ggggcttggt tttgatctaa ctctttcaaa
     1861 acatactcct ttcaatattt ttaggacctt atgaaaacta aggaactaaa ggttgactca
     1921 tgaaaaaaga gcaggttttc acctgctctg caatcttctg acgtgtttat tttggtttct
     1981 gttgagtatg tctgttcccg atgtttccta actctctagt agcaaatatt acgtacttta
     2041 ttgatcgttt cacaagatga cgtgtgcttt caccacacta aaaatttatg aattaggaca
     2101 agtgtcctaa catcaactta taaaagtagg cttttaaccc tatcaataat gtggcttttc
     2161 aaccacgctt cggcattcaa ccctgcctgt ccgtaggcat tttttactcg ggtttatatt
     2221 tgctagaaaa catcatctca ttttctaagc tttattacta tatcatgttt ttaagaactt
     2281 gtaaagtatt ttttgataaa aaacaaaaat ataatagatt gaaactagaa tagtacacct
     2341 ctgcttctaa aacattgtta gaaatagatt ttactgtcct gatcgatttg ttctgttctt
     2401 gtttcatttt actatatgtt cgtaaatgaa agttctataa tgaagttagc cacccagccc
     2461 tcctaaaaat tagatggttc aactagctga tagctcttgt aggcataaga aaacacctct
     2521 gtgttatact tgttgttcaa ccacaaacac aagaaaggca cagaaatgca agacaattat
     2581 actacaaaag gtaaacattt gacaatcgat agccgtcgct taatcgaaag atggaaaaaa
     2641 gaaggaaaat caaatagaga aattgcctct ctacttggaa aagctcctca aactatccac
     2701 actaaaatca agcgtaggac agtccgaaaa tgtcttggaa aagggcgctt caaagaggtt
     2761 tattctgccg actatgctca acagtcttat gaaaataatc gcaagcactc ggtcaagaga
     2821 tcaagcgtga ccaaggaact aaaggaaaag attctccact atcataacca aaaatttttg
     2881 cctgaaatga tggttatggc taaaggggtt aacgtgggaa tttcaaccat ttactattgg
     2941 attcatcatg gaaaattggg gtaaagcaag caggatctgc tttaccctag aaaaggaaaa
     3001 gtgcttaaga aacaggccag caccaacttt aaacctgctg gtcaatccat cgaacagcgg
     3061 cttgaagcta tcaattttcg cttggagaat gggcattatg agattgatac ggttctactt
     3121 acgagagcga aaaactactg cttgcttgtc ttgacggatc gaaaaagtag acatcagatc
     3181 atccgattga ttccaaataa aagtgctgag gtggtcaatc aggctctaaa actcatctta
     3241 aaacaacaca agattctttc catcacggca gataatggaa cggaattcaa tcgcttgtc
//
LOCUS       DAVBEM010000089         3262 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVBEM010000089 DAVBEM010000000
VERSION     DAVBEM010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3262
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.089"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(216..827)
                     /gene="rpsD"
                     /locus_tag="VQ548_002060"
     CDS             complement(216..827)
                     /gene="rpsD"
                     /locus_tag="VQ548_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HET2654844.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1022..2074)
                     /locus_tag="VQ548_002061"
     CDS             complement(1022..2074)
                     /locus_tag="VQ548_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET2654845.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVTKLEKGQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2071..2769)
                     /locus_tag="VQ548_002062"
     CDS             complement(2071..2769)
                     /locus_tag="VQ548_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2654846.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(2936..>3262)
                     /locus_tag="VQ548_002063"
     CDS             complement(2936..>3262)
                     /locus_tag="VQ548_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2654847.1"
                     /translation="VKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMTSS
                     TNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLGLK
                     NKKEEN"
BASE COUNT          912 a          735 c          626 g          989 t
ORIGIN      
        1 ttttttacga aaatctattg aatatgccat aaaaggatta taccacattg tgtactattt
       61 ttggttcatt ttactatatc actttggact atatcggtct agttatgtct aaacgattat
      121 agctggatac taagagaaat caaaaaagca ctaagggaga acgtcccaaa gtgcttaata
      181 tcaaggcctc aaagcctgtc ttattcaata aaatattaca acatcttgtt gtagaattca
      241 acgacaagtg cttcgttgat ttctgggttg atttcgtcgc gttctggcaa gcgagtcaat
      301 gaaccttcca atttttcagc gtcgaatgat acgaatgctg gacgtccaag agtagcttct
      361 actgcttcaa ggattgctgg aactttcaat gatttttcac gaactgagat cacttgacct
      421 ggagttacgc ggtatgatgg gatatcaacg cgtttcccgt caacaaggat gtgaccgtgg
      481 tttacgaatt gacgagcttg acgacgagta gtcgcgagac caagacggta aacaacgtta
      541 tccaaacgac gttccaaaag aagcataaag ttgaaaccta ggattccgcc tttgattttt
      601 gtagcttgta cgaacaagtt acggaattgt ttttcaccta caccgtaagt gaaacgaagt
      661 ttttgttttt cagccaattg caaaccgtat tctgacaatt tagaacggtt gtttggtccg
      721 tgttgtcctg gtacgtagtt acgacgtgcc aattctttac ctgtacctgt aagtgaaagg
      781 ccaaggcgac gagcttgttt ccaagatggt cctgtataac gtgacatatg aatgtcctcc
      841 tgatataaat aatatttcgg tggaaatagt cacttagaaa gccctgattc gtgcagatgc
      901 ccttcgccta aacagccaag gttacttgtc ataagacacc tgttgacgag cttcatgctt
      961 tcctgctgat atttcacaca aaatccattt taccatgaat agctggattt gtaaaggggt
     1021 tttaggcttt attttcacta ccagagagat tgagaacgag ggtaaaggta cttcctagac
     1081 cgtactggct gctgactgtg atttccccac ccaattgatg ggccaattca cgcgcaatcg
     1141 caagtcctaa tccatgacca cctgtcttca tgttacgcga agtttcgaca cgataaaggc
     1201 gtttgaaaat attttccaaa tcctctgggg caatgccctg cccttcatcg gtcacactga
     1261 ttgaaagctg gcccttctcc agcttagtca ccacttccag cttggttcct ggagcagaat
     1321 atttaaaagc gttatcgacc agattcacca agatacgaga aagcttagca taatctccct
     1381 caatccgggc agactctggg attacctgca agtggacatc tcttctctcc tgctcaatca
     1441 aaaactgaaa ttcactcatg cactcaatta agagcttgtc cagaaaaata ctgtctttac
     1501 tggtagtttc cacctgattt ctagctgtgt ttagggtcaa aaaattcaac tcctcaacca
     1561 gtttattgag cctctccgtc tggcgtccaa tggttgctag ataatgagct tgctccgact
     1621 ccttgataat cccatccaaa atcccttcta ccgtcgcttg gatcgaagtg ataggggtct
     1681 taatatcatg cgacaactgg gcaatcatca agcccttttc tcgttcgctt tcttccaagg
     1741 aatcaaagct tacctgcaaa tcatgggaca tctcattaaa agtttgccct aattgctgaa
     1801 attctacagg accttgaacc tccaaatttg aaggaaaatc cttggccgct acccgcttgg
     1861 catgctcctt gagtttgccc aacgacgtaa agactggcaa taggagaaag agactaatcc
     1921 cagcaccgac aaggctggca acgatggtca tcccaagcaa aaagtaaatc tcgcctttcg
     1981 caatcagcat tttttgaaca gcccaaaaaa caaccaaaat ggttaagagg gttgaaataa
     2041 tatatccaac caaaatataa ctttttagtt tcatgtttgt cctctcggtt tctctatctt
     2101 atatcccaac ccccaaactg tcttaatagt gggcgtttgg tcactactat attttgccag
     2161 ctcctgtcga agagcatgga tatgcacatt caaggtattg gtgtcatcca cgtagtcttc
     2221 tttccagatc ttttcataga ggtctgtctt ggagaaaact cgctctggat tgctagctaa
     2281 aatccacagc aattcaaatg atttaacagt taaatccagc atttcttctc ctatttgaac
     2341 ttcatgacta ctatgattca tttttagatt gccaagggaa atcagctctg tttcgccccc
     2401 acgatgaagg cggcgcaaaa tattgtggac acgcaaaacc agctcacgtg ggctaaaagg
     2461 cttagcaata aaatcatctg ctcccaagct caggccgtaa atcttgtcct gttcactggt
     2521 cttagcagta ataaatagga aaggctgctc tggtgataag tattgaacct cactgattaa
     2581 atcataacca tccatccgag gcatcataac atctgtgata atcaaatcaa tcggtttttt
     2641 cttgaacagc tctagcgctt ccagtccatc atgggctacc aagacctgat aacctgcctg
     2701 aattaagtat ctctgatgaa tatctgtgat ttctacctcg tcgtcaacga gtaaaattgt
     2761 ctttcccatc tgtctctcct ttgataaaaa cagtgctata ctgctttaag tataacacta
     2821 tttttattgt tttacgatga ttttaatctg ctattgaaag aaagtcctga ttgctgattg
     2881 agttgttaaa ctaatcttag tcagcccact atccatcatt tatttcctta gctgattagt
     2941 tttcttcttt tttgtttttc aaacctagac caccgagtaa acctgcaagc gcaagcccaa
     3001 ggaaaccaat acttgccatt gatgtttgag tctcaccagt atttggtagc atagctttat
     3061 cctctgacat catcgtatca gacatcttgt tagcagaagc agccatgttt tcacctgcca
     3121 tcgtgttggt agaacttgtc atggtgtcag caggcatgct atctgtagta cctgtagcat
     3181 gattgtgatt catcggagtc acgccagaac cagagttaga aggtgataat gaaccatttg
     3241 ctgtgtctga tgtttcttta ac
//
LOCUS       DAVBEM010000090         3160 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVBEM010000090 DAVBEM010000000
VERSION     DAVBEM010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3160
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.090"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            <1..314
                     /locus_tag="VQ548_002064"
     CDS             <1..314
                     /locus_tag="VQ548_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654848.1"
                     /translation="KKGQFDELVSNLNLSEQEQLDLLQQYKEEHPRRAKRGIKSAIIK
                     KVARFLAAKVGQKSVVEITDYLFEWQDNLEAGAENYLVQYGWDRNIAHWTIKTVSFIF
                     L"
     gene            801..1763
                     /locus_tag="VQ548_002065"
     CDS             801..1763
                     /locus_tag="VQ548_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HET2654849.1"
                     /translation="MEKWENQDKILLDKNKRGKDRNWRGRKLLSLKLADIFKELGYRE
                     TLIERVETCGDTLRFIRREDGSLRLYQAYFCKNKLCPMCNWRRSMKYSYQTSQIVDEA
                     IKEQPKGRFLFLTLTVKNVPGKELNATISQLTQSFDRLFRRAKVKKNLIGFLRSVEVT
                     HNQEEETYHPHIHVLMMVKSSYFSGAGDNYVSQEEWGRMWEQSLKVDYVPMVDIRSVK
                     EIGKGLKGAILETAKYPIKPIKLDVENKQVVGDLYNGLYRKRQLGYGGLFKEIRKRLQ
                     LSNVENGDLVYTSDDNDEMLKGTKIVAIWNATKQNYFVKNKGWN"
     gene            2266..2535
                     /locus_tag="VQ548_002066"
     CDS             2266..2535
                     /locus_tag="VQ548_002066"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654850.1"
                     /translation="MSDEEFKEEAHQFRDKEIKILEEKLKELNISCKVVGINSIKDMN
                     EYKEIMENVNQAKEELKRIDELIAVRSSRIDFLEDKTLRITGNQR"
     gene            2998..>3160
                     /locus_tag="VQ548_002067"
     CDS             2998..>3160
                     /locus_tag="VQ548_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654851.1"
                     /translation="MNKKFLKCGTLFLISCSILGSTIPAVTVFSDEVTITYNSENNSE
                     KNELYNQLSA"
BASE COUNT         1115 a          365 c          653 g         1027 t
ORIGIN      
        1 aaaaaaaagg acagtttgat gagttggtaa gtaatttgaa tttgagcgaa caagaacaat
       61 tagacttgtt gcagcagtat aaagaggaac atcctcggcg agctaaaagg gggataaaat
      121 cagctataat aaaaaaagtc gctcgtttcc ttgctgctaa agtaggacaa aaaagtgtag
      181 tggagataac tgactattta tttgaatggc aagacaattt agaagctgga gcggagaatt
      241 atcttgtaca atatggttgg gatagaaata ttgctcactg gacaataaag acagttagct
      301 ttattttctt ataagtcatt atgaataaag cttggttatt ttggagtgtc atagtcttat
      361 atttttttat aaagtttttt gataaagttt tagatataaa gctttttggt tctattcaaa
      421 tatggctaga taatctccct attccgatga aaatactgtt aacaatagca ttagttttgt
      481 ttttattcat tgtatttcca tatagaggaa aacggtaaaa acggtaatta gatatataaa
      541 aggagctgaa agctccgtaa aaaacctact cgaagagtag gttttttctt atcttgatac
      601 tagtaggaaa taactctcat gctattttta gggtttcgac agggtctaaa cccttgatac
      661 tactgacttt ttaggtaaaa aaatgccctt gacttttttc aacggatctt ttataattta
      721 gttgttcaga aaaaattata aaaagagaaa aaaggcaaag gtatttttgt atttctttgt
      781 aattacaggt aaattataac atggagaagt gggaaaatca agataaaatt cttttagata
      841 aaaataaaag aggcaaggat agaaactggc gaggacgaaa attattaagt ttgaaattgg
      901 cagatatttt taaagagtta ggttataggg aaaccttgat agaacgcgtt gagacttgtg
      961 gagatactct tcgatttatt cgtcgagaag atgggagttt gcgtttatat caagcctatt
     1021 tttgtaagaa taaattgtgt cctatgtgta attggagacg gtcaatgaaa tattcttatc
     1081 aaacatctca gatagttgat gaagcaatta aagaacaacc aaaagggcgt tttcttttct
     1141 tgactttgac tgtgaaaaat gttccaggta aagaattgaa cgcgacaatt agccagctaa
     1201 ctcagtcctt tgaccgtctt tttagacggg caaaggtaaa gaaaaatcta atcgggtttt
     1261 tacgttcggt tgaggtgact cataatcaag aagaagagac ctatcaccct catatccatg
     1321 ttttgatgat ggttaagtct agctatttta gtggggctgg agataattat gtatctcaag
     1381 aagaatgggg gcggatgtgg gaacagtcgc ttaaggttga ctatgtgcca atggttgata
     1441 ttcggtcagt taaagaaata ggaaaaggtc ttaaaggggc aattcttgaa acggcaaaat
     1501 atccaattaa gccgattaag ttagatgttg aaaacaagca agttgttggt gatttgtata
     1561 atgggttata tcgtaaacgg caattgggtt acggtggatt gtttaaagaa attcggaaga
     1621 gattgcaact gtctaatgtc gaaaatggag atctggttta tacttctgat gacaatgatg
     1681 aaatgttaaa aggtacaaaa atagtcgcga tttggaatgc gactaaacaa aactattttg
     1741 taaaaaataa gggttggaat taaagtatca actcttttat tataacataa aaaagagtaa
     1801 aatagacttg atttttttga gtttagatgt atattgaagg tgtgaaaatt aaaaagatag
     1861 ctatgttttt tctgggtata cttgttgggg tatttattgt tctatttttt agaaattatt
     1921 ttgttttact tttggaatat atttttggtt aaaaagcacc ctctaaaaag ggtgcttttt
     1981 gtgcggttat tcgcacgaaa gttctctgca agagttcctc ggaagagcgt ttgtattttg
     2041 attgtacgtc aaaactataa aaacatttac tctttgtcaa agagtagcag aaaagctaga
     2101 ataaaattaa aaattttatt ctagctaata gtgcaagtaa tagcttttgt agcttgcctc
     2161 ttgtccgtta ttcagacaag aggcaggagt ttgtatttgt tctaaatgag tatttcattt
     2221 agaacaaata catcgatgat gaacattgct tacaagaata gagatttgag tgatgaagaa
     2281 tttaaagaag aagctcatca gtttagagat aaagagataa aaatactcga agaaaaatta
     2341 aaggaactta atatttcttg taaggttgtt ggaataaata gtataaaaga tatgaacgag
     2401 tataaagaga ttatggaaaa tgttaatcaa gcaaaagagg aattaaagag aatagatgaa
     2461 ttaatagccg tcaggagctc cagaattgat tttttagagg ataaaaccct tagaattaca
     2521 ggaaaccaaa gatgagctta aaaacgaaat ggagagccta aaaagagatt tatctttttt
     2581 tagaaacgaa aatactcgac tgaaaaatgt agtttcagat tgtatcaagg tagtattttt
     2641 ggggtatttt tagtagaaag tatattgtaa tttctgagcg atttatgccg tgaaagctac
     2701 ttgaccgtaa gctagatcaa agtacgctag tcagggacga gccgaaaggc tgtagcgttt
     2761 cggagcggca cggacaaagt acgtcgacct aggttacttg cggtcaagta gaccatggaa
     2821 taaaacaagc gggtatgata taaaaaagtt atcggcaaac cgaaatatag acttgttttt
     2881 ttgtttataa aaatgtatta ttatattgag aataagattg tttaatttat ttagagagga
     2941 gtgtaagttg atcagtaaac gattttaatt ctgcctttaa ataacaagga gtttgttatg
     3001 aataaaaaat ttttgaaatg tggtacttta tttttgattt cttgttctat tttaggaagt
     3061 actattcctg cagttacagt attttctgat gaagtaacaa ttacttataa ttcagagaat
     3121 aattcagaaa aaaatgaatt atataatcaa ctttctgctg
//
LOCUS       DAVBEM010000091         2624 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVBEM010000091 DAVBEM010000000
VERSION     DAVBEM010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2624
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.091"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            206..520
                     /locus_tag="VQ548_002068"
     CDS             206..520
                     /locus_tag="VQ548_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654852.1"
                     /translation="MWVLGFILFLIFFYSNDSKKIKKLEKKIKRLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            530..736
                     /locus_tag="VQ548_002069"
     CDS             530..736
                     /locus_tag="VQ548_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2654853.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            736..933
                     /locus_tag="VQ548_002070"
     CDS             736..933
                     /locus_tag="VQ548_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654854.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            989..1669
                     /locus_tag="VQ548_002071"
     CDS             989..1669
                     /locus_tag="VQ548_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HET2654855.1"
                     /translation="MGMFVGMFKARVESHEIILDVKALMPWISAICLLIGFISMFLTF
                     NFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAFNITGVVIPLAIFISLSEV
                     IILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLEFFATPKDVLNYINSYDEG
                     ERQANLEQSFRILFQLHQYVLPALYIFLIILSFLTGEIQLLAFLLVGAIHVYINVMQL
                     PMVKRYFK"
     gene            1681..2322
                     /locus_tag="VQ548_002072"
     CDS             1681..2322
                     /locus_tag="VQ548_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2654856.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            2340..2570
                     /locus_tag="VQ548_002073"
     CDS             2340..2570
                     /locus_tag="VQ548_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654857.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
BASE COUNT          766 a          431 c          541 g          886 t
ORIGIN      
        1 atacctacgg caaggtgaag ctgacgtggt ttgaagagat tttagaagag tattaatgat
       61 agataaagtg gtcaggaacc tactcctgac ctttttcttt tgcaaaatga caaaaatcat
      121 aatttttttg acaactatac ttgtcaaaaa gaaaaagatg tgttacaatg taagcaagtt
      181 aagagaaaag aagaaaggag ctatgatgtg ggtactaggg tttatactat ttctgatttt
      241 cttttattct aatgattcta aaaaaatcaa gaaactagag aagaaaatca aaagacttga
      301 gcgaaaagag aaaggaaatg cagaaatgtc gagattatta caagaaatga ttggaaagga
      361 accaattata acgggagtgt atattgggcc agataactgg gaagttgtgg atgttgatga
      421 ggaatgggta aagctacgac gtgtagataa tacgggaaaa gaaaaattca agttgcaacg
      481 tattgaggat atccaaaccg ttgaatttga cggagagtag gtgtgtaaca tgcaactaaa
      541 aaatcgtcta aaagagcttc gagctcgcga tggtctcaat caaaccgacc tagccaaact
      601 ggcaggggtt tccagacaga ccattagcct actagaacgg gatgagtaca ccccatccat
      661 tatcattgcc ctgaaaatat ctcaaatttt caacgaaaca gtcgaatcgg tatttcgttt
      721 ggaggaggac gagtgatgaa caagtataaa gtgatttatt atgtagtggt catagcttta
      781 ttagtcagcg tatttctact gattgggatg gacctaagct ggtttaatcc ctatcaaagc
      841 gaccaatttg tttgggtcta ctttgctctc atcccagtaa ttgaatggat tgaaaagaaa
      901 tccaaaaatc tagcaagtga aaaaggagaa tgaatatgaa aaagaaacgt agattgttat
      961 ttttgatgtc tattgtcttg gggggttctt gggcatgttt gtagggatgt ttaaggcacg
     1021 tgtcgaatcc cacgaaatta ttttagatgt aaaagccttg atgccatgga tatcagctat
     1081 ttgtttactg ataggtttca ttagtatgtt tttgactttc aatttcttaa agaaaagcag
     1141 aaaatttcat tccttgtatc aagaggaaat ggatgacgat ctgaatgaaa cctattatgt
     1201 gcaaatgtat cggaatcttg agtttggaac cattgctttt aatattacag gtgtagtgat
     1261 tccattggct atttttattt cattaagtga ggtgattata ttgcatacaa accctcaaac
     1321 atttttcctt tctttcttac tctttgtggt attcttagtc gctcaaaaat ctctttttaa
     1381 aaccattgcg attgttcgtc agtttgattt ggaatttttc gctacaccaa aggatgtctt
     1441 gaactatata aattcttatg atgaagggga gcgtcaggct aatttggaac agagttttcg
     1501 aattttattc caattacacc aatatgtctt accagcctta tatatttttc ttattatcct
     1561 ttctttcttg acaggagaga ttcagttact agctttcttg cttgtaggag ccatccatgt
     1621 ttatatcaat gtgatgcagt tacctatggt aaaacgttat ttcaaataaa ggagttatct
     1681 atgaaattac ttaaaaacct tggctggttt cttctagccc ttctatcctt tttctttatc
     1741 tatggcttta ttcaggggct cgcgactgcg tcgcttgctt taggcgcttc accctatgct
     1801 gttactctac tctatgtggt cttggctgga gtatatgtgt acggcattta caaatggtat
     1861 cagaaagctc ctgtttatat tgagaagagc ggctttaacc gatttatttg gcttcctgcc
     1921 ttggtttggt tcttatctct ggtcgttcaa ttcttcttgc cagatgatcc ttcagtaaat
     1981 cagcaaatag cgacagactt gaccttgtct caaccacttt tctcattctt tgctgtggtt
     2041 atttttgctc ctttgacgga agagattgtt tttagaggga tgttagcacg ctatctcttt
     2101 cctaagcagg acaatagtaa acgaaccctg atttttcttc tggtatctag tcttctattt
     2161 gccttgattc attttccagg tgatgtgcaa caattttttg tctattttag ccttggtttt
     2221 agtttgggtt tggcttacat tagcagaaaa ggtctggtct acagtatttc tcttcacgct
     2281 ttgaataatt tagtcggctt tttgatgatt ctcatgctat aatagagtca ggaggtcaca
     2341 tgaaacgagt aattttatta gcagtgattc aggcagtcgt tctatttttc atcattggag
     2401 cgctagctta tgccttcaaa ggcgatttct tctataacta tctagcagtt gtctttgctc
     2461 ctattgcagg tgtactgcgt tttgggacgg cttacataac ggaaattgtc ttgcctcgaa
     2521 aggcagccga aatcgctgaa aagcgtaaag caggcaaaaa ttcaaaataa aagagtccgg
     2581 tgaagttcat cggatttttg tattatactc aatgaaaatc aaag
//
LOCUS       DAVBEM010000092         2618 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVBEM010000092 DAVBEM010000000
VERSION     DAVBEM010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2618
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.092"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            76..993
                     /locus_tag="VQ548_002074"
                     /pseudo
     CDS             76..993
                     /locus_tag="VQ548_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822901.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            complement(1033..1977)
                     /gene="manA"
                     /locus_tag="VQ548_002075"
     CDS             complement(1033..1977)
                     /gene="manA"
                     /locus_tag="VQ548_002075"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HET2654858.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTILVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVESWTLEGQDLELIVSHP"
     gene            complement(2109..2390)
                     /locus_tag="VQ548_002076"
     CDS             complement(2109..2390)
                     /locus_tag="VQ548_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HET2654859.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDSVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            2455..2577
                     /locus_tag="VQ548_002077"
                     /pseudo
     CDS             2455..2577
                     /locus_tag="VQ548_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          698 a          608 c          475 g          837 t
ORIGIN      
        1 gtgcatcagt tagttgttta cttgcttcat cattcataga actactatgc catattttgt
       61 ttcgcaggaa gtctgatcat ttcaaatcca gccattgctc taggagctca agcgaccttt
      121 atcctattga atatcttcat tgtatcacgt ggggttcaaa aagggattga aagagcttcg
      181 aaagtcatga tgcccctgct ctttatcatc tttgtcgtca tcatcgaacg ctctctcagt
      241 ttgccaaatg ccatggaagg ggttctttac ttcctcaaac cagatttttc aaaactgact
      301 agcgctggtc tcctctatgc tctgagacaa tctttctttg ccctctcact aggggttaca
      361 gccatgttga cctatgcttc ttacttggac aagaaaacca atctggtcca gtcaagaatc
      421 tccatcgtag ccatgaatat ctcggtatcc atcatggcag gtctagccat tttccaagct
      481 cggtccccct tcagactgaa tattgaaggg ggaccgagct tggtctttat cgtcttgcct
      541 caactctttg acaagatgcc ttttggaacc attttctatg tcctcttcct ctttgcgact
      601 gtcacttctt ctgtcgttat gctggaaatc aatgtagaca atatcaccaa tcaggacaac
      661 agcaagcgtg ctaaatggag tgttatttta ggaattttga cctttgtctt tggcattcct
      721 tcagccctat cttacggtgt catggcggat gttcacattt ttggtaaagc cttctttgac
      781 gctatggact tcttggtttc caatctcctc atgccatttg gagctctctt cctttcactt
      841 tttacaggct atatctttaa aaaggctctt gcaatggagg aactccatct cgatgaaaga
      901 gcatggaaac aaggactgtt ccaagtctgg ctcttccttc ttcgtttcgt cattccaatc
      961 atcatcgtgg tcttcatcgc ccaatttatg taatcaaaag gacttgagta atgaactcag
     1021 gtcctttctt ttttatggat gactaacaat taattctaaa tcttgccctt ctagagtcca
     1081 agattcaaca tcacttggta ggataaagtg tctccctttt tggattggat agtttttccc
     1141 gtcaacagtt agttgacctt gaccagccaa gacactcaac aagctgtagt cagctgtctt
     1201 ttcaaagtta acttttccag taatttccca tttgtaaact gcgaagaaat cattggatac
     1261 aaggatagtg gaacgtagat catctgcttt gattgtcact ggacggctat ttgcgggttc
     1321 accaatgttc aagacatcga tagatttttc aaggtgaagt tcacgtaaat tgcccttgtc
     1381 atccttacgg tcaaagtcat agacacggta agtggtatcg ctagactgct gggtttcaag
     1441 aatcaagata cccgccccga tagcgtgcat ggtaccgctt ggtacataga agaaatctcc
     1501 tgctttaact ggcacttttg tcaacagcgc atcccagttc ttatcctcga tttgctggcg
     1561 gagttcttct tttgacttgg cattgtgacc gtagataatc tctgaacctt catctgctgc
     1621 aatgatgtac caacattctg tttttccaag ttcgccttca tgctcgagtc cataagcatc
     1681 gtctgggtga acttggacac tgagccagtc gttggcatcg aggatcttgg tcaaaagtgg
     1741 aaatacaggt tctggacgat tgccaaataa ttcacggtgt tccgcataca aagtagcaag
     1801 atctgttccc tcgtaacgac cattggcaac tttagaaaca ccatttagat gagctgagat
     1861 agcccagtac tctccgactt tttcacttgg gatgtcgtag ccaaactcat cacgtagctt
     1921 ggtaccaccc cagatttttt cttgcataac tgattgtaaa aataatggtt ctgacatctt
     1981 aatctcctgt ctgatttttc tcccctcatt atagcaaaaa aagagttcca tttgaactct
     2041 tttttacatc ttataaagca gggagaagat tttataaaaa tagtaaacaa atgtgctcta
     2101 ctcgatgctt acaccattgc tataaatgac atgtaccaat agaaggactt cttcttgcta
     2161 cgtttgagag tcccatttcc tacattatct cgatctacat agataaagcc atagcgctta
     2221 ttcatttccc ctgtgccagc tgaaaccgaa tcgatacagc cccatgtcgt ataaccaagc
     2281 aagtcaaccc cgtctttgta aatggcatct cgcatggcct tgatgtgggc ctctaagtaa
     2341 gtaatccgat agtcatctgc tacataacca ttctcatccg gtgtatccat agcaccgagt
     2401 ccattttcta cgataatact atactaaaat caaaaagcat tatataatag tgatatgaaa
     2461 tcaactaaag aagaaatcca aaccatcaaa acacttttta aagactctcg tacagctaaa
     2521 tatcataaat gccttcaaat cattctattt cgtctgatgg gcaaatctta taaagactcc
     2581 gactaatatt ggttttgcat ttattcctcc atacacac
//
LOCUS       DAVBEM010000093         2398 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVBEM010000093 DAVBEM010000000
VERSION     DAVBEM010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.093"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(26..428)
                     /locus_tag="VQ548_002078"
                     /pseudo
     CDS             complement(26..428)
                     /locus_tag="VQ548_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(373..555)
                     /locus_tag="VQ548_002079"
     CDS             complement(373..555)
                     /locus_tag="VQ548_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET2654860.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            912..>2398
                     /gene="pcpA"
                     /locus_tag="VQ548_002080"
     CDS             912..>2398
                     /gene="pcpA"
                     /locus_tag="VQ548_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HET2654861.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDGA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLWYYLNESGSKATGWVKDKGLWYYL"
BASE COUNT          837 a          359 c          397 g          805 t
ORIGIN      
        1 tgagccttca tagcgtggca tttcttttta cttccgtcac atcaatcatt accgtgtcct
       61 cagaactgag aggagttctt gaaatcgtaa caccaccttt gaacaagagt tacttcaacc
      121 cattagctcc gacggattaa gttgctttcg tgaataccaa aatcagccgc aatttcttca
      181 taagtgcggt attctcgcac atattgaaga gtggccataa gaaggtcttc taggcttaat
      241 ttaggttttc gtccaccttt tgtgtgttta agttgataag ctgtttttaa cacagctaac
      301 atctcttcaa aagtggtgcg ctgaacacca acaagacgct taaatcgtgc atcggttagt
      361 tgtttacttg cttcataatt tcgcagggag tctattgact ctttggtagg tgtcaatgtt
      421 tttttcatct atcccgagaa ttattttccc gccatttgta tttgcaaatg ctgagtaggt
      481 ttcccagaaa gactctggaa gattgttttt agcttttttg tattctaaat caaccccttc
      541 aaattttaag tccatatttt tcctttacat ctgttttttg tggttctggt atttgttcaa
      601 gttgagtgat aatatagcga attgaatttc gagagttttt actcagttaa tttctttttt
      661 aacccacttt aatttctttt ttaacccact ttaatttctt ttttaacacg ggttaaaaaa
      721 gaaattaaag tgggttaatt tttcttgact taaaatttaa aaatgatata ctgtgtttat
      781 ggagagatga caatttataa aatgtactac tctattctac tagataatga ttgaataaaa
      841 ctttttataa caacggctag caaagttata attttatatc tattagaaaa taaatatgta
      901 aggaaattta aatgaaaaaa actacaatat tatcattaac tacagctgcg gttattttag
      961 cagcatatgt ccctaatgaa ccaatcctag cagatactcc tagttcggaa gtaatcaaag
     1021 agactaaagt tggaagtatt attcaacaaa ataatatcaa atataaggtt ctaactgtag
     1081 aaggtaacat aggaactgtt caagtgggta atggagttac tcctgtagag tttgaagctg
     1141 gtcaagatgg aaaaccattc acgattccta caaaaatcac agtaggtgat aaagtattta
     1201 ccgttactga agtagctagt caagctttta gttattatcc agatgaaaca ggtagaattg
     1261 tctactatcc tagctctatt actatcccat caagcataaa aaaaatacaa aaaaaaggct
     1321 tccatggaag taaagctaaa actattattt ttgacaaagg cagtcagctg gagaaaattg
     1381 aagatggagc ttttgatttt tctgaattag aagagattga attgcctgca tctctagaat
     1441 atattggaac aagtgcattt tcttttagtc aaaaattgaa aaagctaacc ttttcctcaa
     1501 gttcaaaatt agaattaata tcacatgagg cttttgctaa tttatcaaat ttagagaaac
     1561 taacattacc aaaatcggtt aaaacattag gaagtaatct atttagactc actactagct
     1621 taaaacatgt tgatgttgaa gaaggaaatg aatcgtttgc ctcagttgat ggtgttttgt
     1681 tttcaaaaga taaaacccaa ttaatttatt atccaagtca aaaaaatgac gaaagttata
     1741 aaacgcctaa ggagacaaaa gaacttgcat catattcgtt taataaaaat tcttacttga
     1801 aaaaactcga attgaatgaa ggtttagaaa aaatcggtac ttttgcattt gcagatgcga
     1861 ttaaacttga agaaattagc ttaccaaata gtttagaaac tattgaacgt ttagcctttt
     1921 acggtaattt agaattaaaa gaacttatat taccagataa tgttaaaaat tttggtaaac
     1981 acgttatgaa cggtttacca aaattaaaaa gtttaacaat tggtaataat atcaactcat
     2041 tgccgtcctt cttcctaagt ggcgtcttag attcattaaa ggaaattcat attaagaata
     2101 aaagtacaga gttttctgtg aaaaaagata catttgcaat tcctgaaact gttaagttct
     2161 atgtaacatc agaacatata aaagatgttc ttaaatcaaa tttatctact agtaatgata
     2221 tcattgttga aaaagtagat aatataaaac aagaaactga tgtagctaaa cctaaaaaga
     2281 attctaatca gggagtagtt ggttgggtta aagacaaagg tttatggtat tacttaaatg
     2341 aatcaggttc aaaggctact ggttgggtta aagacaaagg cttatggtat tacttaaa
//
LOCUS       DAVBEM010000094         2039 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVBEM010000094 DAVBEM010000000
VERSION     DAVBEM010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2039
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.094"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            <1..105
                     /locus_tag="VQ548_002081"
     CDS             <1..105
                     /locus_tag="VQ548_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2654862.1"
                     /translation="AFLREIAAHFDCAVPSVWAALKQIKVTLKKDDDL"
     gene            92..625
                     /locus_tag="VQ548_002082"
     CDS             92..625
                     /locus_tag="VQ548_002082"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET2654863.1"
                     /translation="MTIFKEQESEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            983..1237
                     /locus_tag="VQ548_002083"
     CDS             983..1237
                     /locus_tag="VQ548_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654864.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRITNRLANDLNNVLKQV
                     DKDTPNTPTWLNSAASKAKDDDRVYKLLKTLIPGENYLSC"
     gene            1348..>2039
                     /locus_tag="VQ548_002084"
     CDS             1348..>2039
                     /locus_tag="VQ548_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET2654865.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSYRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDG"
BASE COUNT          744 a          336 c          416 g          543 t
ORIGIN      
        1 gcttttttac gggaaattgc ggcacatttt gattgtgctg ttccttcagt atgggcagct
       61 ttaaagcaga ttaaggtcac tttaaaaaaa gatgacgatc tttaaggaac aagagtcaga
      121 gaaagtcgct gagtttcttg atattttgga taacctaaaa gatttaccaa tcgtatatat
      181 tgatgaaaca ggaatcgacc gctacctcta tcgtccttat gcaggggctc ctagagggga
      241 gaaagtctat gaaaagatta gcggacgtcg ttttgagcga acttcaattg ttgcaggaca
      301 agtagacgga gagtttatag ctcccatgat ttacaagaaa agcatgacaa gcgatttctt
      361 tgtggagtgg ttcaaaacgc aactcctacc tgctttgaag acacctcatg ttattgtcat
      421 gggcaatgct agttttcatc ccaagaacat tttggatgaa ctctgcatcc aagataaaca
      481 ctttttctta cctctaccac cttattcacc ggatttgaat cctattgagc aagcttgggc
      541 tatcttgaaa aagaaagtga cggatttatt aagggaagtt ccaactattt ttgaatgttt
      601 ggaatgcttt tttaaaacta gatgactata acggttctaa aggaacctat cgagtagtca
      661 ttaaaactaa ggatactgct ggttaagaga agacggtata cgatcaaacc attcaccgtg
      721 tagccgaaat cgttcagaat gaagacttgt atcagaatga agacttgtat aagaaaggtt
      781 tgaatgttga acttgcgcac caacaaatta agggattttt tgaagcagag tttaaaaatc
      841 gtattaatgg agttcttaat actaaaataa aaaatagtac attaaatcgt gtaaataaaa
      901 aaactataca ccagagcaac aaaaactcca tgatcaattt gaagcagaag caacggaaga
      961 tgctaaaaaa caaggcgata ttgtgttgaa tgttgaccag gatttcatga gcatatctaa
     1021 gtctaataaa agtggttcag actggaagaa aactttcaca gtgaggataa ccaataggct
     1081 agcaaatgac ttgaataatg tcttgaaaca ggttgataaa gatactccta ataccccaac
     1141 ttggctaaac tcagctgctt ctaaagctaa agatgatgac agagtatata aactactgaa
     1201 gactcttata ccaggagaaa attacctatc atgttaagga taatcagcta gaagtagaaa
     1261 cagataaata cacatatact gccgctagaa atggtagtaa ggaagttggt attcaagagt
     1321 cagatatagc agcaactcta agtgccgatg aatataattc taatcgccaa acctttgaga
     1381 gagaatacaa atacaaaagc aaatgccctt aataatggtt gggctagatc tggttctgaa
     1441 gagttcaaaa agttctccca ctttgtaggg gtagacaaag ggattgtgcg aacgaatgta
     1501 ctgactggta aaaaactatc tgataaaatt aggaaagaag tgggctctgg agatagcaaa
     1561 ctaggaaaag gcggctattt ctctactggg gatgttctat taggaaaaga tgttgtttct
     1621 tataccgtac aagtattttc agagaataat gaaagagtag gagtaaacac tcaaagttac
     1681 cgtgttcagt ataatctccc aattctagct gacttttcag tcatccaaga tactgtggaa
     1741 ccatcacgaa ccgttgttga aaaaatcatt ccaaaactaa atattcccga agaagagaaa
     1801 gggaaaataa ccgaagaaat caagaaaaag aaaaaaacct cagaattggc agaactaatc
     1861 tcagaaaatg tgaaagttcg ctatgttgat gaacaagggc gtttgctatc attgaaaaat
     1921 gatactggaa ttggagaaaa agaaagtgac ggaacctaca ttaccaataa aaaacaactg
     1981 attggtacca gctacaatgt cacagataaa aaactcagta gcatgactac tactgacgg
//
LOCUS       DAVBEM010000095         1671 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVBEM010000095 DAVBEM010000000
VERSION     DAVBEM010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1671
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.095"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            100..1575
                     /locus_tag="VQ548_002085"
     CDS             100..1575
                     /locus_tag="VQ548_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HET2654866.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNIVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
BASE COUNT          474 a          335 c          334 g          528 t
ORIGIN      
        1 tccagtattt gacaatattg aagcagctat taaagaacac ggattaagct aattctaatt
       61 tgttaacatt catataacat aaaaaaggga ggaactgtta tggatgcaat ctttgaccta
      121 atcggaaagg ttttcaatcc cattttagaa atgggtggac ctgtcatcat gttaatcatt
      181 ttgacagtat tggctttact ttttggagtg aaattctcca aagcgcttga aggtggtatc
      241 aaacttgcca tcgctcttac aggtatcggt gctatcatcg gtatgctaaa tggtgctttc
      301 tcagcatcac ttgcaaaatt cgttgaaaac actggtatcc aattgagtat taccgacgtt
      361 ggttgggcac cactcgcaac aatcacttgg ggttctgctt ggacactata cttcttgctc
      421 atcatgttga ttgtcaacat agtgatgcta gctatgaaga aaacagatac acttgacgtt
      481 gatatctttg atatctggca cttgtctatc acaggtctct tgattaaatg gtatgctgat
      541 aacaatggtg tgagtcaagg ggtttcactc tttattgcta cagcagctat cgtccttgtc
      601 ggtgtgttga aaattatcaa ctctgacttg atgaaaccta catttgatga ccttcttaac
      661 gccccaagtt catcaccaat gacatcaact cacatgaact acatgatgaa cccagttatc
      721 atggttttgg ataagatttt tgaaaaattc ttcccaggcc ttgataaata tgactttgat
      781 gctgctaaat tgaacaagaa aatcggtttc tggggatcta aattcttcat cggtttcatc
      841 cttggtatcg ttatcggtat tatgggaact ccacatccaa ttgcaggtgt tgcagatgca
      901 gataaatggc gtcttgttat caaaggatgg ttgtctcttg gtttgactgc cggtgtatct
      961 ttggaactct tctcacttat cggttcatgg ttcatcgcag ccgtagaacc actatcacaa
     1021 ggtattacaa acgttgctac taaacgtctt caaggacgta aattcaatat cggtcttgac
     1081 tggccattca tcgctggtcg tgctgaaatc tgggcttgtg ccaacgtact tgcaccaatc
     1141 atgttgattg aagcagtgct tctttcaaaa gttggaaatg gtatcttgcc acttgcaggt
     1201 atcatcgcta tgggtgttac tccagctctc ttggttgtaa ctcgtggtaa attgctccgt
     1261 atgattatct tcggaacact cttgttgcca ctcttccttc tttcaggtac acttattgca
     1321 ccatttgcaa cagaacttgc taaaggtgta ggtgccttcc cagaaggtgt gagccaaact
     1381 caattgatta ctcactctac tcttgaagga ccaatcgaaa aacttcttgg ttggacaatt
     1441 ggtaacacta caactggtga tatcaaagca atccttggtg cagtagtctt ccttgtattc
     1501 tatatcggta tctttgcttg gtacagaaaa caaatgatca aacgtaacga agagtacgca
     1561 gcaaaagcaa aataatgcgc tcctataaaa tataaactca atgaaaatca aagagcaaac
     1621 taggaaacta gccacaggtt gctcaaaaca cagttttgag gttgtagata a
//
LOCUS       DAVBEM010000096         1651 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVBEM010000096 DAVBEM010000000
VERSION     DAVBEM010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1651
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.096"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            108..407
                     /locus_tag="VQ548_002086"
     CDS             108..407
                     /locus_tag="VQ548_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic biosynthesis protein"
                     /protein_id="HET2654867.1"
                     /translation="MDSYAINFWESKGVGIDKKILEFIQKNITVIKNKNFLNKDFDIY
                     VKKIHNLFFVISTLVSKEQYMGIVSSQIHMFANRMGISPTIEVTMLDFFLREDSD"
     gene            409..1179
                     /locus_tag="VQ548_002087"
     CDS             409..1179
                     /locus_tag="VQ548_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="HET2654868.1"
                     /translation="MEKYFFDISIFEKIKKVLSYQSKYWEISKPRDKYSFKSQNRISG
                     SNSIKFKDFELDYELESLGKILLKRRSFLLNEFDKNASFDKLIYLLKTVFSPTNCKFV
                     FGEEVPLFSYPTSGALNSITPFVYIDNMDEVKNGIYEVKYDGLEFKKSMNIIDLETFT
                     PITSKNSDVQNNSFKKVNMIIMLCSNYENIFNKYGLLAYRLLHLEAGHIAQNIQLVST
                     ALGIKSLPMGGWFDDKIETFINEISDKKNIYLYAIAVG"
     gene            1199..1363
                     /locus_tag="VQ548_002088"
     CDS             1199..1363
                     /locus_tag="VQ548_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654869.1"
                     /translation="MNAEDKFRELENENKLLKLHNKELENEIQNGWKFWIWVTVPILG
                     LIYAIIQKIF"
BASE COUNT          608 a          181 c          269 g          593 t
ORIGIN      
        1 ataactatta ttacgaaaaa aaattcttgt gtaaaattct attgactttc tatattattt
       61 ttgtatttca taacgaatgt aatttaacaa gtgaagaaat tttaaagatg gattcctatg
      121 ctattaattt ctgggagagt aaaggggtcg gtattgacaa aaaaatcttg gaatttattc
      181 aaaaaaatat tacagttatt aaaaataaaa attttttgaa taaagatttt gatatttatg
      241 ttaaaaagat tcataattta ttctttgtca tttctacttt agtttcaaaa gagcaataca
      301 tggggatagt ttcttcccaa atacatatgt tcgcaaatag gatgggaatt tctcccacca
      361 ttgaagttac catgctagat ttttttctga gggaggattc tgattaatat ggaaaaatat
      421 ttttttgata tttctatttt tgaaaaaata aaaaaagtat tatcatacca atctaaatat
      481 tgggaaatat cgaagcctag ggataagtac agtttcaaaa gtcaaaatag aatatctggc
      541 tctaatagca ttaaatttaa agattttgag ttagattatg aactggagtc acttggtaaa
      601 atacttttaa aaaggagatc gtttttacta aatgaatttg ataagaatgc gagttttgac
      661 aaactgattt acttgttgaa aactgtattc tctcctacaa attgcaagtt tgtatttgga
      721 gaagaggttc ctttatttag ctatcctaca tcaggtgcgt taaattcaat tactcctttt
      781 gtttatattg ataatatgga tgaagtaaag aatggtatat atgaagtaaa gtatgacgga
      841 cttgaattta aaaaaagtat gaatattata gacttagaaa catttacccc aataacaagt
      901 aaaaacagtg acgtacaaaa taattcattt aaaaaggtaa atatgataat tatgttatgt
      961 tcgaattatg aaaatatttt caataaatat ggattattag cttatcgact tttgcattta
     1021 gaggctggtc atattgcaca aaatatccag cttgtttcta ctgcgctagg aataaaaagt
     1081 ttaccgatgg gaggttggtt tgatgataaa atagaaactt ttattaatga aattagtgat
     1141 aaaaaaaata tttatctcta tgcaattgca gttggataaa tttaaggagg aagtgtagat
     1201 gaacgcagag gataaatttc gcgaactaga aaatgaaaat aaacttctaa aacttcataa
     1261 caaggagctt gagaatgaaa ttcaaaatgg atggaaattt tggatatggg taactgtccc
     1321 tattttaggt ttgatatatg ctattattca aaaaattttt taattatgct agtttgtcag
     1381 gttgagtagt ttttgttcaa aatttaataa acttttttca atgaagatta tctaaagatt
     1441 gcttctcaga tgagaatggc ttctctatct tatataaatt atcttcatag agtgtcctgt
     1501 tattcatgtt atcacagaat agatagtttt tttggctcta taatatttgt agtgggtaaa
     1561 tcccctatag atattatgga gcctattttt gtgtagaaaa aaagtcccat atcatctata
     1621 atgaaaagca accaaactat cattagaaag a
//
LOCUS       DAVBEM010000097         1642 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVBEM010000097 DAVBEM010000000
VERSION     DAVBEM010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1642
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.097"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(<1..737)
                     /locus_tag="VQ548_002089"
     CDS             complement(<1..737)
                     /locus_tag="VQ548_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET2654870.1"
                     /translation="MCYTCCSTTNTRKAQRCKTIILQKANKGKSNREIASLLGKAPQT
                     IHTEIKRRTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHN
                     QKFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLPYPRKGKALKKQASTNFKPAG
                     QSIEQRLEAINFRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVV
                     NQALKLILKQHKILSITADNGTEFNRLS"
     gene            complement(1111..1509)
                     /locus_tag="VQ548_002090"
     CDS             complement(1111..1509)
                     /locus_tag="VQ548_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2654871.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT          468 a          323 c          275 g          576 t
ORIGIN      
        1 gacaagcgat tgaattccgt tccattatct gccgtgatgg aaagaatctt gtgttgtttt
       61 aagatgagtt ttagagcctg attgaccacc tcagcacttt tatttggaat caatcggatg
      121 atctgatgtc tactttttcg atccgtcaag acaagcaagc agtagttttt cgctctcgta
      181 agtagaactg tatcaatctc ataatgccca ttctccaagc gaaaattgat agcttcaagc
      241 cgctgttcga tggattgacc agcaggttta aagttggtgc tagcctgttt cttaagcgct
      301 tttccttttc tagggtaagg caaatcctgc ttgcttaacc ccaattttcc atgatgaatc
      361 caatagtaaa tggttgaaat tcccacgtta acccctttag ccataaccat catttcaggc
      421 gaaaattttt ggttatgata gtggagaatc ttttccttta gttccttggt caagcttgat
      481 ttcttgaccg agcgcttgcg attgttttca taagactgtt gagcatagtc ggcagaataa
      541 acctctttga agcgcccttt tccaagacat tgtcggactg tcctacgctt gatttcagtg
      601 tggatagttt gaggagcttt tccaagtaga gaggcaattt ctctatttga tttccctttg
      661 ttcgcctttt gtagtataat ggttttgcat ctctgtgcct ttcttgtgtt tgtggttgaa
      721 caacaagtat aacacaaagg tgttttctta tgcctacaag agctttcatt atttccattt
      781 tcttttggat ttcactctat tctgaaaaac ttgtgtatat ttactgaagc tagcaagtct
      841 tacctgtaaa tttaatgaaa gcaacacaaa atccgagagg ggaatctcgg attaatgtca
      901 atttaaaaag atagagagtt tttagtttaa ataaattgtt ttaaaatatc aacaacatca
      961 cttcttttct taacctgata agccttgatt cctaattttg gggctacgat tatattgtcc
     1021 tcaatatcgt ctagaaagac acaatttcta ggttataact ggtatttatc gatagttact
     1081 catatatatc agtccacctc catactcacc ttacagattc ttttgataat aatatctttg
     1141 cctaatgtag agatagtctt gcaaagaaaa aacttccttg tagccatgtt tctgataaaa
     1201 gtccggtgcc tggaactggt aagtattgac aaaggcaaaa caacaatttc gattcttagc
     1261 ttcactttct gcctgttgca atagttttga accgattcct tgccctcgca gttcctcttt
     1321 tacaaacaaa tactcgattt ctagccaatt tccaaaagtc tctgctatca aacccgcaag
     1381 gagattgccc ttttcatctt cgacataaag attaagtggc tcactttcag cctcttctct
     1441 ttttgaacgg ttataaacac gaatcagatt ccctatttct tgcgatttat gtgattcctt
     1501 attttccaat ctaaagtata atgaaatgaa ataaaacatg cgcaaatcga ttaaggaatt
     1561 taatctaatt tctaacaatg tcttagaaat caaagtgtac tattttaact tcaatgcact
     1621 atacatctaa tactcaataa aa
//
LOCUS       DAVBEM010000098         1586 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVBEM010000098 DAVBEM010000000
VERSION     DAVBEM010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1586
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.098"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            84..491
                     /locus_tag="VQ548_002091"
     CDS             84..491
                     /locus_tag="VQ548_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2654872.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATSFKEVQKPLENFN
                     HIAWFPIDEAIQNLKRGSHKWAIESWKKQHKIG"
     gene            656..955
                     /locus_tag="VQ548_002092"
     CDS             656..955
                     /locus_tag="VQ548_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HET2654873.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVNEANIKTLYSEKLIGISIPIK"
     gene            1216..1539
                     /gene="tnpB"
                     /locus_tag="VQ548_002093"
     CDS             1216..1539
                     /gene="tnpB"
                     /locus_tag="VQ548_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET2654874.1"
                     /translation="MMIVLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
BASE COUNT          544 a          314 c          282 g          446 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaaagc gaatacagac tatattgctc gctatggcgt atatgcagtt atccctaatc
      121 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      181 gagaaattga agcaggtgaa aatcatcagg aagccctaaa gcgtgagttg attgaagagc
      241 ttggtttcac agcagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      301 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact tctttcaaag
      361 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      421 tccaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      481 agattggcta atactcttcg aaaataaaat tcaaaccacg tcagcgtcgc cttaccgtac
      541 tcaagtatag cctgcggcta gcttcctagt ttgctctttg attttcattg agtataaatc
      601 aagcgacttt attcaaaaag tgctataata gaattagaaa atcggaggaa atattatgaa
      661 gcttatcaat acgacaaact cacactcgca acttgtaaaa agtcaactag aaagtaccga
      721 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
      781 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
      841 aaccattcaa gaatttttct tgaaacgtaa aattgataag acctctgtta atgaagccaa
      901 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
      961 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttccataaca aaacgcatag
     1021 taacaagagt ttctacaccc actattatac gtttttatca ttttgaaatc tgctgctaat
     1081 caatgaagaa gcaaagatca aactaggcag ctagttacaa gttacgtaag cgcgtcataa
     1141 caaggtatct atcctaattc cccaacttcc agtatactag ataaaaaata attatcagag
     1201 gaaaggtatt gtactatgat gattgtacta agtgatttag gtcaagttca ccttgtttgt
     1261 ggcaagacag atatgaggca gggaatagac tcattagcct atgtagttaa aacccacttt
     1321 gaattggatc ctttctccgg tcaagtcttt ctcttttgtg gtggacgtaa agaccgcttt
     1381 aaagcccttt actgggatgg tcaaggattt tggctactat ataaacgctt tgagaacggc
     1441 agactgactt ggcccagtac agaaaaggat gtcaaagctc tcacatctga acaagtagac
     1501 tggcttatga agggcttttc tatcactccc caaatatagt ggatttaaac tagaatagta
     1561 cacctctact tctaaaacat tgttag
//
LOCUS       DAVBEM010000099         1389 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVBEM010000099 DAVBEM010000000
VERSION     DAVBEM010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1389
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.099"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(704..1389)
                     /locus_tag="VQ548_002094"
                     /pseudo
     CDS             complement(704..1389)
                     /locus_tag="VQ548_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          386 a          283 c          287 g          433 t
ORIGIN      
        1 tacgtgacag agtccagttc tatcagaccg ttcgttttac agacacaagt gaagtaggat
       61 tacttcgatt agttgtttac cccttcgctc cacttccatt acagaagttt cctcactact
      121 atgggctcgg ctgacttctc atgattcgtt gttactacgc tttcggcgct catgagacct
      181 cacgggataa gccgtacatc tttcctcgtt tatacaagat atgaggacgt taaaaggtta
      241 caatgaaaat aggaaatctg acgcagagtc tttagactct aggaagattt atctttttca
      301 catagacctt agtccgaatt caattactct cgtgatttac gcatataggt tacgactacc
      361 tttttggact ttagagtttt aagccccctt atccgctgta tacgccttac tatcacgttc
      421 ctgttcgtag agcctcgatt tcgctatccc ttcctctgac gattcttatt tcctgcgtca
      481 gacttaaaac ggtctatccc cagaccgttt taatccgcta cctcacgata gtcaggcttg
      541 ggaatcgcta ttgggttcac cggtagcagg tgcccacgga ggacttacac ctcagatgca
      601 cgacatgccc gtcgtactta aaatcagcct aaatgattca ggctgatttt tctattgatt
      661 caaaaaaacg gctctttgtc aactgtagtg ggttgaagaa aagctaagat cgagaaagga
      721 caaatttcgt cctttctttt ttgatattca gagcgataaa aatccgtttt ttgaagtttt
      781 caaagttccg aaaaccaaag gcattgtgct tgataagttt gatgagatta ttggtcgctt
      841 ccaatttggc gtttgaatag ggtagttgaa gggcgttgat aatcttttct ttatctttga
      901 ggaaggtttt aaagacagtc tgaaaaatag gatgaacctg cttcagattg tcctcaataa
      961 gtccgaaaaa tttctctggt tccttattct ggaagtgaaa aagcaagagc tgatagagct
     1021 gatagtggtg tttcaagtct tccgaatagc tcaaaagctt gtctaaaatc tctttattgg
     1081 ttaaatgcat acgaaaagta ggacgataaa aacgcttatc actcagttta cggctatcct
     1141 gttgtatgag cttccagtag cgcttgatag ccttgtattc atgggatttt cgatgaaact
     1201 gattcatgat ttaaacacgc acacgactca tagcacggct aagatgttgc acaatgtgaa
     1261 agcgatcaag aacgatttta gcattcggga gtgaaacagt ctgggagact gtttcagcct
     1321 gagcctagaa atttgaaagc gaagctgtct agctaagtca tagtaagggc taaacatatc
     1381 catagtaat
//
LOCUS       DAVBEM010000100         1326 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVBEM010000100 DAVBEM010000000
VERSION     DAVBEM010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1326
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.100"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            236..676
                     /locus_tag="VQ548_002095"
     CDS             236..676
                     /locus_tag="VQ548_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2654875.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            673..1131
                     /locus_tag="VQ548_002096"
     CDS             673..1131
                     /locus_tag="VQ548_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HET2654876.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
BASE COUNT          421 a          288 c          249 g          368 t
ORIGIN      
        1 ccttgccaga gggagtaaaa tagtggtata ctcaataaaa atcaaagagc aaactagaaa
       61 gctaggcgca gacagctcaa aacactgttt tgaggttgta gataaaactg acaaagtcaa
      121 caactatcct acggcaagac gacgctgacg tggtttgaag agatttttga agagtattaa
      181 taaaggtgta caagaagtga gattaatttt gtatgaaaaa caaggagaga aatttatgaa
      241 agtagaatta cagattagtg agacttacga ggaggaaaag ctgattgtcc aagcacctca
      301 gccgacagat aaagttcaga aagtcatcga gttcgcagaa aatctggacc aaagagaaaa
      361 aatcaaaggg aaaatcgatg atcaggtcta tctagttgag attggcaaga ttcagcgctt
      421 ctatatcgag aatcggaagg ttctagcaga aaccgcgagt cagacctaca gcattgattt
      481 gcgactctat caggttctta aactcttgcc aaccaatttt atccaaattt cccaatcaga
      541 aatcatcaat atcgattcca tctctcacct caagctcacg ccaaacggtc tggtagaaat
      601 tttcttgaaa aacgaaagct tcacctactc ttcacgccgt tatctaaaaa ccatcaagga
      661 gaaattagaa ctatgaaaaa acaagtattt cacgatgcag ctgccggtgt tcttatcggc
      721 ctcatcctct ctatcctctt ttcactcatt tatgcaccaa atacctacgc accactaaat
      781 ccctactctc tcatcggcca agtgatggat cagcatcagg ttcacggtgc cttggtcttg
      841 ctctactgca cacttatctg ggcagccatt ggtatgctct tcaactttgg caatcgctta
      901 ttcagccgtg actggagcat gcttcgtgcc actctgactc atttcttcct tatgctggct
      961 ggctttgtcc cactagcaac tcttgctggt tggttccctt tccactggat tttctacctc
     1021 cagctcatta tcgagtttgc gattgtctat ctcatcatct gggctattct ctataaaaga
     1081 gaggctaaaa aagtagatca catcaatcaa ctcttggagc atagaaaata ggaacctcat
     1141 aataagcaaa tccgagaaag aaacttctcg gtttttcttt atcctgctgc accttactat
     1201 agtgaaatga aataagaaca ggataaatcg atcaggacag tcaaatcgat ttctaacaat
     1261 gttttagaag cagaggtgta ctattctagt ttcaatcctc tatatcataa cagttatttc
     1321 agatct
//
LOCUS       DAVBEM010000101         1122 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVBEM010000101 DAVBEM010000000
VERSION     DAVBEM010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1122
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.101"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(1..459)
                     /locus_tag="VQ548_002097"
                     /pseudo
     CDS             complement(1..459)
                     /locus_tag="VQ548_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(695..1006)
                     /locus_tag="VQ548_002098"
     CDS             complement(695..1006)
                     /locus_tag="VQ548_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654877.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYVCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
BASE COUNT          348 a          236 c          186 g          352 t
ORIGIN      
        1 cgcatcatca taagaaacca cttcagcgac aaacttgtac tcagggattt tacgacgagc
       61 accaaacaac tgctcatttt cagatggtgt accatagtaa aatcctgtag ccagttcacg
      121 ttgggcaacc ttccacatct cgtccaccaa gtcttgtttg atagcttcaa acttttcagg
      181 actttcaaga taggcatcca caaccgcctt gtagcagttg gttactgtta atacatagtg
      241 aatagactcc atacgtcctt cgatttttag actgtccaca ccattttcaa tcatatctgg
      301 aatgtggtca atcatagaca tgtcaacggc tgacattgaa aattcttctg gaatctcacc
      361 ctgcaaactc ttacgttctt tcccaaatgg catatcgtaa aggtcgtatt tccaacggca
      421 tgactgagaa catccaccac ggttggcatc acgcatactc tagacgcaat tctaatcttt
      481 tagactttgc ataataactg ttaaacagtt gaaaattaac ccagttttaa caagtagtca
      541 aaataccaga taaaggaaaa aaagtcttta aaatcttaaa aacgcatagt atcaggtatt
      601 gaacaatctt gatattatgc gttttattgt gggaagattt acttcatttt ctcttggaat
      661 tgagttttct cctacttcaa aactagatga tttgctattt aaaatagcgt tccttatgat
      721 tttggcaacc tggattaaag cgagaaaaac aaaaggggca acttaagctt tctttatatt
      781 gcttatatgt tagtagtttt agacaaacac cacataaaat aggcttatcc tgtatcaaag
      841 ataagggata cggctcaaaa gggtgatttt ctaatgaatc atgacaccga taacaagcat
      901 agtacttttt acaaacatag cattgtaaag caataatatc cagcttgcta tggtaatgaa
      961 tgcatcttgt ttgcttatcc actaagaaac cctgtgcctc tatcatttcc ttttcctttc
     1021 ttaagctcga actgtgacgc tggttccatc ttccttataa agattgatga gtccttcttt
     1081 taatgcacga accatgtctc cagcttgaac aggttgaggc ac
//
LOCUS       DAVBEM010000102         1054 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVBEM010000102 DAVBEM010000000
VERSION     DAVBEM010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1054
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.102"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            <1..555
                     /locus_tag="VQ548_002099"
     CDS             <1..555
                     /locus_tag="VQ548_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2654878.1"
                     /translation="KDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGTE
                     IPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIPA
                     THNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPIS
                     NHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(503..1048)
                     /locus_tag="VQ548_002100"
     CDS             complement(503..1048)
                     /locus_tag="VQ548_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2654879.1"
                     /translation="MNWVVIKIKDIFSINTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT          380 a          165 c          153 g          356 t
ORIGIN      
        1 aaagacgaaa caacctctta tcctatatat gaaatcccag aagcatggag atatattaaa
       61 tttgctagcc tagttaactt cagaatagga aaaactcctc cacgcagtga agctactttt
      121 tggggaactg aaataccttg ggtatctata tcagatatgc ctatatctgg ttatgtaact
      181 aatacgagag aatctatttc taaattagca ttaaaatcaa agaaaataga catttcacct
      241 aaaggaactt tattaatgag ttttaaatta tctattggaa aagttgccat attggatatt
      301 cctgccactc ataatgaagc cattatatcg atattcccct atgctaataa agaaaatatt
      361 atcagagatt acttaatgat atttttgcca cttatctcta ctttaggtga ttcaaaagat
      421 gctataaaag ggaaaacatt aaatagtacc agtatctccg aattattaat ccctatttct
      481 aatcatgaag agatgaaaag aatcatttcc aaagttgatt tactttttca aaaagtttct
      541 caactttttg agtaataagt tcctgttcct caaaaggagc taacggaatt aatagctcgc
      601 ttagtgtagt tttaggaata ttatataaag cttgacctga tagtttagtt attgctttca
      661 attgtttata aaataacgga gaggacaagt taaataatag aaattttgaa ataatctctg
      721 aactttcgaa tggtgttaat tggaaaataa atccaccagc cacaacacca tcatagtctt
      781 tatcgattct tgcaaacttt ccaatatgtt ctaaagaggt tgatacaggt gttattagct
      841 gattatgttt taaataaact tgctcagagg agatgaattg tgtatcaatg tagtaatcat
      901 tatccaacag agaaaattct aaaggcttaa tattaccacc acgtataatt ctaacacctt
      961 tattattaat gcttaaatcg cccttcttgt aagaaagacc tgtatttatt gaaaaaatat
     1021 cttttatttt tataacaacc caattcatag gtat
//
LOCUS       DAVBEM010000103         1053 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVBEM010000103 DAVBEM010000000
VERSION     DAVBEM010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1053
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.103"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            <1..>1053
                     /locus_tag="VQ548_002101"
     CDS             <1..>1053
                     /locus_tag="VQ548_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET2654880.1"
                     /translation="HKEIIAKLDYDAPSCPECGNQLKKYDFQKPSKIPYLETTGMPTR
                     ILLRKRRFKCYHCSKMMVAETPLVKKNHQIPRIINQKIAQKLIEKISMTDIAHQLAIS
                     TSTVIRKLNDFHFEHDFSRLPKIMSWDEYAFTKGKMSFIAQDFDNLNIITVLEGRTQA
                     VIRNHFLRYDRAVRCQVKIITMDMFSPYYDLAKQLFPCAKIVLDRFHIIQHLSRAMSR
                     FRVQIMNQFERKSHEYKAIKRYWKLIQQDSRKLSDKRFYRPTFRMHLTNKEILDKILS
                     YSEDLKHHYQIYQLLLFHFQNKDPEKFFGLIEDNLKQVHPLFQTVFKTFLKNKEKIVN
                     ALQLHYSNAKLEATNNL"
BASE COUNT          336 a          233 c          169 g          315 t
ORIGIN      
        1 acacaaggaa atcatcgcca aactggacta cgacgcccca tcttgccctg agtgcggaaa
       61 ccaattgaag aaatatgact ttcaaaaacc ttctaaaatt ccttatcttg aaacgactgg
      121 tatgcctact agaattctcc ttagaaaacg ccgtttcaag tgctatcact gttcaaaaat
      181 gatggttgct gagactcccc tggtaaagaa aaatcaccaa atccctcgta tcatcaacca
      241 aaaaattgct caaaagttaa ttgaaaaaat ttctatgact gatattgccc atcagctggc
      301 catttcaact tcaactgtca ttcgcaagct caatgacttt cactttgagc atgatttttc
      361 tcggcttcca aagattatgt cttgggatga gtatgccttc actaagggaa agatgagttt
      421 cattgcgcaa gattttgata atcttaatat tatcactgtt cttgaaggca gaacacaagc
      481 tgtcatccga aatcactttc ttcgctacga tagagccgtt cgttgtcaag tgaaaatcat
      541 tacgatggat atgtttagtc cttactatga cttggctaaa cagctttttc cgtgtgctaa
      601 aatcgttcta gatcgtttcc atattatcca acatctcagc cgtgccatga gtcgttttcg
      661 tgttcaaatt atgaatcagt ttgaacgaaa atctcatgaa tacaaggcta tcaagcgtta
      721 ctggaaactc atccaacagg atagtcgtaa attgagcgat aaacgttttt atcgccctac
      781 ttttcgcatg cacttaacaa ataaagaaat tcttgacaag attttaagct attcagaaga
      841 cttgaaacac cactatcaga tctatcaact cttacttttt cactttcaga acaaagaccc
      901 tgagaaattt ttcggactca ttgaggacaa tctgaagcag gttcatcctc tttttcagac
      961 tgtctttaaa acctttctaa agaacaaaga gaaaatcgtc aacgcccttc aactacacta
     1021 ttctaatgcc aaactggaag cgaccaataa tct
//
LOCUS       DAVBEM010000104         1042 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVBEM010000104 DAVBEM010000000
VERSION     DAVBEM010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1042
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.104"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            91..>1042
                     /locus_tag="VQ548_002102"
     CDS             91..>1042
                     /locus_tag="VQ548_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET2654881.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
BASE COUNT          370 a          187 c          215 g          270 t
ORIGIN      
        1 ctgttgtcaa atgaaatgtg atttaaggta taagaaaaca cctctgtgct atacttgttg
       61 ttcaccacaa acacaaggaa aggcacagag atgcaagaac attatacccc aaaagggaaa
      121 catttgacaa tagataaccg tcgcttgatt gagcggtgga agaatgaaaa taagtccaat
      181 cgtgaaattg caggcttgtt aggaaaggcg cctcaaacga ttcataatga agtcaaaaga
      241 ggtacaactt tacaacaagt gagaaaaggg ctatacaaaa aggtctattc tgccgattac
      301 gcacaaactg tttaccaatt caatcgaaaa cggtcggtga aaaagttaat tttaacaaag
      361 gaaatcagag agaagatctt acactatcat aagcaaaaat tttcgcctga aatgatggtt
      421 aacaagaagc aagtgaaagt tggtatttca accatctact actggtttca taatggtcat
      481 ttaggattga cgaaggccga catgctttat cccagaaaaa ggaaaggtgt caagaagcaa
      541 gctagtccga actttaagcc ggcaggtaaa tctatcgaag aacgtcctga cgttattaat
      601 cttcgcttgg aaaatggtca ttatgaaatt gataccgtcc tactgactaa gataaaaaat
      661 tattgcctgt tagtcttaac cgaccggcgg agcagacacc aaattataag gttaattcca
      721 aataaaactg ctgaatctgt caatcaggcg cttacgttac tattagggga gcatcgtatt
      781 ctgtccatta ctgcagataa tggttcggag ttcaaacgat tgtctgaggt atttcctgag
      841 gaacatatct actacgcaca tgcttactct tcatgggaga gaggttcaaa tgaaaatcat
      901 aatcgattaa ttcggagatg gttacctaaa ggaaccaaga aaacgactcc gaaagaagta
      961 gcttttatcg aaaattggat taacaactac cctaaaaaat gcttggacta caagtcgcca
     1021 agtgaatttc ttttgggtgg ct
//
LOCUS       DAVBEM010000105         1035 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVBEM010000105 DAVBEM010000000
VERSION     DAVBEM010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.105"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(<1..990)
                     /gene="ltrA"
                     /locus_tag="VQ548_002103"
     CDS             complement(<1..990)
                     /gene="ltrA"
                     /locus_tag="VQ548_002103"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET2654882.1"
                     /translation="MSKLLDKILSRDNMLEAYNQVKSNKGSAGIDGITIEEMDGYLRQ
                     NWRLTKELIKQRKYKPQPVLRVEIPKPNGGIRQLGIPTVMDRMIQQAIVQVISPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAAAKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVWRFKLKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSL"
BASE COUNT          270 a          226 c          183 g          356 t
ORIGIN      
        1 caatgagaaa tagtttatcc atcctcgaat agacaaattc agttgctcaa tacgtcttgt
       61 taggtctata ctccatttcc tctgtgttag tttcttcaat ttaagcttaa atctccaaac
      121 actatcttga tgtggacgac ttttccaacc atctgatgat ttccagaacc cgaaacctag
      181 atatttcaac tctcttggtc tggtaatctt agtcttggtc atgtttactt tcagacctag
      241 ccgtttctca ataaaacgac tgactgaata catcacacgc ttagcggctg cctcgcttcc
      301 gaccgtaatc acacaatcgt ctgcgtagcg aacaaatcga agccctctct tttctaattc
      361 cttgtccaat tcattaagca tgatattgga taagagagga gataaatttc ctccctgtgg
      421 cgtgccaact agcgttttat aacgttgacc gttaatgata acacctgaat gaagatattt
      481 acgaatcaag gattccgtat ctccgtcttc gataatgtta tgtactaagg acatcaatct
      541 atcttgagga actgtatcga aaaatttctc taggtctatg tccactatcc actcatagcc
      601 gtcatttaag tactctaaga gcttcatgat ggctttttca catgacctat ttggtctgaa
      661 tccatagctc gtatctgaga aatggggttc acaaataggg ctaataactt gaacaatggc
      721 ctgttgaatc attctatcca taactgttgg aattcctagt tggcggatgc ctccgtttgg
      781 tttgggaatc tcaactctaa gaactggttg aggcttatat tttctctgtt ttatcagttc
      841 cttagtcagg cgccagtttt gtctgagata gccatccatc tcttcgatag taattccatc
      901 aatcccagct gagcctttat tagattttac ttgattgtag gcttcaagca tattgtcgcg
      961 tgataatatt ttatctagca attttgacat gtgcctattc ctttcttgtt ttggtgcctg
     1021 agggacatct tatat
//
LOCUS       DAVBEM010000106          922 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVBEM010000106 DAVBEM010000000
VERSION     DAVBEM010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..922
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.106"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            122..590
                     /locus_tag="VQ548_002104"
                     /pseudo
     CDS             122..590
                     /locus_tag="VQ548_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          336 a          139 c          172 g          275 t
ORIGIN      
        1 gagaagagga ttgccatctt ctccattttt atgtgcagag ttatagtggc ttgatgctgg
       61 gaaagtacac tgtgactgct aaaacattcc tagaagctgc tttgatttcc ctaatctatt
      121 tatgcaaatt ttatgttatt ttactataac agttgttgct aagccaaata atagtgggga
      181 agttcattta gacgtaagca ttgaagataa tcagggaggt agtgggtata atttcagttc
      241 tgtttcaagt agctcacaaa cagctaaata tgaaggaact ggttataata acaattcatc
      301 attatatata acgattgata aaacgtctga tgcaacagct cttttgaaat taaagttgaa
      361 taatgttgat aatcaacctg ctactgaagt tcctagttca ggaattactg taaaattaaa
      421 tgctaaagat aatgctggaa actggacaag tgcttcgaat aaagacaagt gcttcgaata
      481 aaaaagaaat aacagtaaaa attgtttctg ctaaaccgac atatccagac aaaatcttag
      541 tgaaaaatcc tgataatata aaagatacag aaaaaaatgc cattattgaa aaattgaaag
      601 aggcaaataa aaatcatcca gcaggagctc caacctttgc taaaggtgaa ggagagcatg
      661 caaatgatat tgtagcaact tattcagatg gtacaactta ttatgtaccg ttaaatgatg
      721 tgacaaaata tgcgaggtag tggctgtacc actcacttat tcacctcccc gtgatttgta
      781 gtagtgatag gctttctcac tattattata aaacaaaata aagatcacaa cactttttca
      841 ttctgtgttg tgccttgagt gaaacgaaag gaatgaatta taaatatgaa aagtatagtc
      901 actagcatag atgagcgctt gc
//
LOCUS       DAVBEM010000107          830 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVBEM010000107 DAVBEM010000000
VERSION     DAVBEM010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.107"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            21..830
                     /locus_tag="VQ548_002105"
                     /pseudo
     CDS             21..830
                     /locus_tag="VQ548_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558050.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS1515 family transposase"
BASE COUNT          266 a          174 c          162 g          228 t
ORIGIN      
        1 aaaagtgtta tactattttt atggaaacag tatacgacaa agcacaaaaa cttaactcaa
       61 aaaacttcaa actattgatt ggtgtcaaaa aggaaacctt tcaactcatg ctagaacacc
      121 tgaattcagc ctatcagatt cagcaccgaa aaggtggacg tccacgtagt ctgcccatgg
      181 aagaccagct cattatgacc ctccgttact tgcgatatta tcccactcag cgtctgctgg
      241 cctttgattt tggcgtcggt gtagctacgg taaatgccat catcacttgg gtggaggata
      301 cacttcgtgc gtcaggtagc tttgatttgg accatttaga agccccgagt gctgctgtgg
      361 ctattgacgt gaccgaaagt ccgattcagc gtccaaaaaa aaccaaagca aaaattattc
      421 tggtaaaaag aaacgacaca ccttaaaaac tcaaattatg ctggatttga cgacacataa
      481 agtctgtcaa atggcctttt ctgacggaca tacgcatgat tttactctct tcaaagaaag
      541 tattggacaa agtttgcctg aaacgacgct tgcctttgtt gacctaggtt atttaggcat
      601 cttgaaattt catgagaata ctttcattcc tgctaaaaat tccaaaaatc gccgcctgag
      661 tgaggatgat aagcagttaa ataaagagat gtcagcgata cgaattgaaa ttgaacattt
      721 taacgctaaa ttcaagacct tccaaatcat gtcagtccct tatcgtaacc gcagaaaacg
      781 tttcgagtta cgggcggaat taatttgtgc catcatcaat tatgaagtga
//
LOCUS       DAVBEM010000108          773 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVBEM010000108 DAVBEM010000000
VERSION     DAVBEM010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..773
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.108"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(<1..>773)
                     /locus_tag="VQ548_002106"
     CDS             complement(<1..>773)
                     /locus_tag="VQ548_002106"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654883.1"
                     /translation="SDALVLAEAEALVEAEADALVEADSDALVLAEADALVDADSEAL
                     VLAEADALVDAEAEALVLAEAEALVLAETEALVLAEADALVDAEAEALVLAEADALVL
                     AETEALVLAEAEALVLAEAEALVDAEAEALVLAEAEALVDADSDAEVLAEAEALVDAE
                     AEALVLAEAEALVLADSDALVDAEAEALVDAEAEALVDAEADALVDAEAEALVDAEAE
                     ALVDAEAEALVLAEADALVDAEAEALVLAEADALVEAEA"
BASE COUNT          193 a          261 c          172 g          147 t
ORIGIN      
        1 tcagcttcgg cctcaacaag tgcgtcagct tcagcaagca ccagtgcttc ggcttcagcg
       61 tcgacaagtg cgtcagcctc agcaagcacc agtgcctcag cttcagcatc aacaagtgct
      121 tcagcctcag cgtcaacaag tgcttcagct tcagcatcaa caagtgcgtc agcttcagca
      181 tcaaccagtg cctcagcctc agcgtcgaca agtgcctcgg cttcagcatc gacaagtgca
      241 tctgaatcag caagcacaag tgcttcagct tcagcaagta ccagcgcctc agcctcagca
      301 tcaaccagtg cttcggcttc agcaagtacc tcagcgtctg aatcggcatc aacaagtgct
      361 tcagcttcag caagtacaag cgcctcagct tcagcatcaa ccagtgcttc ggcttcagca
      421 agcaccagtg cctcggcttc agcaagcacc agtgcctcag tctcagcaag caccagtgcg
      481 tcggcttcag caagcacaag cgcctcagct tcagcatcaa ccagtgcgtc agcctcagca
      541 agtaccagtg cctcagtctc agcaagcacc agtgcttcgg cttcagcaag cacaagcgcc
      601 tcagcttcag catcaaccag tgcgtcagcc tcagcaagta ccagtgcctc tgaatccgca
      661 tcaacaagtg catcggcttc agcaagcacc agtgcgtctg agtcagcctc aacgagtgcg
      721 tcggcttcag cctcaaccag cgcctcagcc tcagcaagta caagtgcatc aga
//
LOCUS       DAVBEM010000109          692 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVBEM010000109 DAVBEM010000000
VERSION     DAVBEM010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.109"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(74..147)
                     /locus_tag="VQ548_002107"
     tRNA            complement(74..147)
                     /locus_tag="VQ548_002107"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="VQ548_002108"
     tRNA            complement(157..242)
                     /locus_tag="VQ548_002108"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="VQ548_002109"
     tRNA            complement(250..321)
                     /locus_tag="VQ548_002109"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="VQ548_002110"
     tRNA            complement(344..416)
                     /locus_tag="VQ548_002110"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="VQ548_002111"
     tRNA            complement(435..516)
                     /locus_tag="VQ548_002111"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
     gene            complement(522..594)
                     /locus_tag="VQ548_002112"
     tRNA            complement(522..594)
                     /locus_tag="VQ548_002112"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(559..561),aa:Lys,seq:ttt)
     gene            complement(619..691)
                     /locus_tag="VQ548_002113"
     tRNA            complement(619..691)
                     /locus_tag="VQ548_002113"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(656..658),aa:Asp,seq:gtc)
BASE COUNT          179 a          205 c          149 g          159 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
      601 aacttgcgtt accttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
      661 ggcgacgtga taaccgctac actacgggac ct
//
LOCUS       DAVBEM010000110          611 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVBEM010000110 DAVBEM010000000
VERSION     DAVBEM010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..611
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.110"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(189..>611)
                     /locus_tag="VQ548_002114"
     CDS             complement(189..>611)
                     /locus_tag="VQ548_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET2654884.1"
                     /translation="KPNEEKPQTEKPEEDKEHDEVSEPTHPESDEKENHAGLNPSADN
                     LYKPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAVET
                     LTGLKSSLLLGTKDNNTISAEVDSLLALLKESQPTPIQ"
BASE COUNT          155 a          121 c           93 g          242 t
ORIGIN      
        1 gatgaagttt tttctcaact tcttttactt tattaaatag ttttctaaac cggttattta
       61 accatttaat taaccagtaa atagtttact atttaaaatt acttttgtca agtttctgtt
      121 acgtttttct aaaaaagaga agtaacacga aaggttactt ctccataaaa tatgctccat
      181 tcattttact actgtatagg agtcggttga ctttctttta acaaagccaa gagactatct
      241 acttctgctg aaatagtgtt attatctttc gttccgagaa gaagactact ttttagacca
      301 gtcaatgtct ccacagcatt ttgtctaata ctagaatctg ttactttttc tagcaaggcc
      361 tccgcctctg ctatcttagc gttaataaca gaatgctcta cttgaggaat ttcagcctca
      421 tctgtagtat cttcagcttc ttcctctgtc tcttccgtat cagtgcttgg tttataaaga
      481 ttatctgctg aaggatttaa accagcgtga ttctcttttt catcagattc agggtgagtt
      541 ggctcactta cttcatcatg ttccttatct tcctcaggtt tttctgtctg aggtttctcc
      601 tcgtttggtt t
//
LOCUS       DAVBEM010000111          603 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVBEM010000111 DAVBEM010000000
VERSION     DAVBEM010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..603
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.111"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
BASE COUNT          187 a          108 c          158 g          150 t
ORIGIN      
        1 gtcgtatatc tgaggtgtaa gtcctcggtg ggcacctgct accggtgaac ccaatagcga
       61 ttcccaagcc tgactatcgt gaggtagcag ggagaggaag ggatagcgaa atcgtggctc
      121 tacgaacagg aacgtgatag taaggcgtat atagcggata aggaggcttc aaactctaaa
      181 gtccaaaaag gtagtcgtaa cctatatgtg taaatcacga gagtaattga attcggacta
      241 aggtttgtgt gaaaaagata aatctttcta gagtctaaag actctgcgtc agatttccta
      301 ttttcactgt aaccttttaa cgtcctcata tcttgtataa acgaggaaag atgtacgact
      361 tatcccgtga ggtttcatga gcgctgaaag cgtagtaaca acgaatcatg agaagtcagc
      421 cgagcccata gtagtgagga aacttccgta atggaagtgg agcgaagggg tgaatactca
      481 aacagtctgg ggagagactg tttgaggtct gtcgctagaa agagaaaacg acagatcgaa
      541 gtaatcctac ttcacttgtg tctgtaaaat gagtggtctg atagaactgg actttgacac
      601 gta
//
LOCUS       DAVBEM010000112          569 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVBEM010000112 DAVBEM010000000
VERSION     DAVBEM010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..569
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.112"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(<1..>569)
                     /locus_tag="VQ548_002115"
     CDS             complement(<1..>569)
                     /locus_tag="VQ548_002115"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654885.1"
                     /translation="AEALVDAEADALVEADSEAEVLAEADALVDAEADALVLAEADAL
                     VDAEADALVLAEAEALVDAEADALVLAEAEALVDAEADALVLAEADALVLAEAEALVD
                     AEAEALVDADSEALVDAEADALIDADSEADVLAEAEALVDAEAEALVDADSEALVDAE
                     AEADVDAEADALVDAEADALVDAEAEALV"
BASE COUNT          137 a          187 c          130 g          115 t
ORIGIN      
        1 tcaaccagcg cctcagcttc agcatcaacg agtgcgtcgg cttcagcatc aacgagtgca
       61 tcggcttcag catcaacgtc tgcctcagct tcagcgtcaa ccagtgcctc tgaatcggca
      121 tcaaccagtg cttcagcctc agcatcgaca agcgcttcgg cttcagcaag tacatcagct
      181 tctgaatctg catcaataag tgcgtcggct tcagcgtcaa ccagtgcctc tgaatcggca
      241 tcaaccagtg cttcagcctc agcatcaacg agtgcttcgg cttcagcaag tacaagtgcg
      301 tcagcttcag caagcacaag tgcgtcagct tcagcatcaa cgagcgcctc ggcttcagca
      361 agcaccagtg cgtcagcttc agcatcaacg agtgcctcgg cctcagcaag tacaagtgcg
      421 tcagcctcag catcaaccag tgcatcagcc tcagcaagta ccagtgcatc agcttccgca
      481 tcaacgagtg catcagcctc agcaagcacc tcagcttctg aatcggcctc aacgagtgcg
      541 tcagcctcag cgtcaacgag tgcttcggc
//
LOCUS       DAVBEM010000113          399 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVBEM010000113 DAVBEM010000000
VERSION     DAVBEM010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..399
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.113"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            1..73
                     /locus_tag="VQ548_002116"
     tRNA            1..73
                     /locus_tag="VQ548_002116"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:34..36,aa:Met,seq:cat)
     gene            87..160
                     /locus_tag="VQ548_002117"
     tRNA            87..160
                     /locus_tag="VQ548_002117"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Ile,seq:cat)
     gene            171..260
                     /locus_tag="VQ548_002118"
     tRNA            171..260
                     /locus_tag="VQ548_002118"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:207..209,aa:Ser,seq:tga)
     gene            274..347
                     /locus_tag="VQ548_002119"
     tRNA            274..347
                     /locus_tag="VQ548_002119"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:308..310,aa:Met,seq:cat)
BASE COUNT           85 a           97 c          116 g          101 t
ORIGIN      
        1 gcggtgtagc tcagctggct agagcgtccg gttcataccc gggaggtcgg gggttcgatc
       61 cccttcgccg ctataatgat cttgtcggac ctttagctca gctggttaga gctctcggct
      121 cataaccgag tggtcgtagg ttcaagtcct acaaggtcca tttgaatatt ggaggattac
      181 ccaagtccgg ctgaagggaa cggtcttgaa aaccgtcagg cgtgtaaaag cgtgcgtggg
      241 ttcgaatccc acatcctcct tttatattat taacgcggga tggagcagct cggtagctcg
      301 tcgggctcat aacccgaagg tcgtaggttc aaatcctgct cccgcaataa ggctcggtag
      361 ctcagttggt agagcaatgg attgaagctc catgtgtcg
//
LOCUS       DAVBEM010000114          393 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVBEM010000114 DAVBEM010000000
VERSION     DAVBEM010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..393
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.114"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            <1..>393
                     /locus_tag="VQ548_002120"
     CDS             <1..>393
                     /locus_tag="VQ548_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET2654886.1"
                     /translation="YLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFR
                     NRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSK
                     EKQEELERVLSNERFRGRQRVLRDLRIVF"
BASE COUNT          143 a           57 c           93 g          100 t
ORIGIN      
        1 taccttcatt tatgggaatt gtcggattgg gaccaagaag gcatgctctg cttacatgaa
       61 ttgattagta gagaagaagg actggtagac gatattccac gtttaaggaa atatttcaaa
      121 accaagtttc gaaatcgaat tttagactat atccgtaagc aggaaagtca gaagcgtaga
      181 tacgataaag aaccctatga agaagtggga gagatcagtc atcgtataag tgaggggggt
      241 ctctggctag atgattatta tctctttcat gaaacactaa gagattatag aaacaaacaa
      301 agtaaagaga aacaagaaga actagaacgc gtcttaagca atgaacgatt tcgagggcgt
      361 caaagagtat taagagactt acgcattgtg ttt
//
LOCUS       DAVBEM010000115          363 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVBEM010000115 DAVBEM010000000
VERSION     DAVBEM010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..363
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.115"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(1..287)
                     /locus_tag="VQ548_002121"
                     /pseudo
     CDS             complement(1..287)
                     /locus_tag="VQ548_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          113 a           59 c           84 g          107 t
ORIGIN      
        1 tgaaaaagca agagttgata gagttgatag tggtgtttca agtcttccga ataactcaaa
       61 agcttgttta aaatctcttt attggttaag tgcatacgaa aagtaggacg ataaaaacgt
      121 ttatcactca gtttacggct atcctgttga atgagtttcc agtagcgctt gatagccttg
      181 tattcatggg attttcgatg aaactgattc atgatttgga cacgcacacg actcatagca
      241 cggctaagat gttgtacaat atgaaagcga tcaagaacga ttttagcatt cgggagtgaa
      301 acagtctggg agactgtttc agcctgagcc tagaaatttg aaagcgaagc tgtttagcca
      361 agt
//
LOCUS       DAVBEM010000116          311 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVBEM010000116 DAVBEM010000000
VERSION     DAVBEM010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..311
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.116"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(<1..>311)
                     /locus_tag="VQ548_002122"
     CDS             complement(<1..>311)
                     /locus_tag="VQ548_002122"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2654887.1"
                     /translation="ALVLAEADALVDAEAEALVDAEAEALVDADSEADVLAEADALVD
                     ADSDALVDAEAEALVDADAEALVLAEADALVLAEAEALVDAEAEALVLAEADALVEAE
                     A"
BASE COUNT           77 a           99 c           71 g           64 t
ORIGIN      
        1 tcagcttcgg cctcaacaag tgcgtcagct tcagcaagca ccagtgcttc ggcttcagcg
       61 tcgacaagtg cctcagcttc agcaagtacc agtgcgtcag cctcagcaag tactagcgcc
      121 tcagcatcag cgtcaacaag tgcttcggct tcagcgtcaa cgagtgcgtc tgagtcagca
      181 tcaacgagtg cgtcagcctc agcaagcaca tcagcttctg aatccgcatc aacaagtgct
      241 tcagcctcag cgtcaacaag tgcttcagct tcagcatcaa ccagtgcatc agcttcagca
      301 agtactagcg c
//
LOCUS       DAVBEM010000117          292 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVBEM010000117 DAVBEM010000000
VERSION     DAVBEM010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.117"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            51..>292
                     /locus_tag="VQ548_002123"
     rRNA            51..>292
                     /locus_tag="VQ548_002123"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           90 a           54 c           81 g           67 t
ORIGIN      
        1 gaaaaaaaca ataaatctgt cagtgacaga aatgagtgag aactcaaact tttaatgaga
       61 gtttgatcct ggctcaggac gaacgctggc ggcgtgccta atacatgcaa gtagaacgct
      121 gaaggaggag cttgcttctc tggatgagtt gcgaacgggt gagtaacgcg taggtaacct
      181 gcctggtagc gggggataac tattggaaac gatagctaat accgcataag agtagatgtt
      241 gcatgacatt tgcttaaaag gtgcacttgc atcactacca gatggacctg cg
//
LOCUS       DAVBEM010000118          288 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVBEM010000118 DAVBEM010000000
VERSION     DAVBEM010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.118"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            <1..>288
                     /locus_tag="VQ548_002124"
     CDS             <1..>288
                     /locus_tag="VQ548_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET2654888.1"
                     /translation="NRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEW
                     FDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRNKNG"
BASE COUNT           93 a           59 c           59 g           77 t
ORIGIN      
        1 caaccgcgtg aaagcagcta agaaggtgcc acttgatcgt atgccttaca atcttcaata
       61 tactgtagaa gtcaaaaacg gtagtttaat catacctcat tatgaccatt accataacat
      121 caaatttgag tggtttgacg aaggccttta tgaggcacct aaggggtata ctcttgagga
      181 tcttttggcg actgtcaagt actatgtcga acatccaaac gaacgtccgc attcagataa
      241 tggttttggt aacgctagcg accatgttca aagaaacaaa aatggtca
//
LOCUS       DAVBEM010000119          277 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVBEM010000119 DAVBEM010000000
VERSION     DAVBEM010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.119"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            <1..>277
                     /locus_tag="VQ548_002125"
     CDS             <1..>277
                     /locus_tag="VQ548_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2654889.1"
                     /translation="QRIIEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAM
                     QGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQG"
BASE COUNT          126 a           37 c           47 g           67 t
ORIGIN      
        1 aacaacgcat aatagaagca atcgaatcag ctttagaaaa agtagatgaa tatgctgaaa
       61 gttataatag actagaacag ctagataaag aatttccaga taaactaaaa aaatctattc
      121 ttcaatatgc tatgcaagga aaattagttg aacaagaccc aaatgatgaa tcagtcgaag
      181 ttttacttga aaaaatacga gcagaaaaac aaaaactctt tgaagaaggc aagattaaaa
      241 agaaagattt ggacatttct attgtttccc aaggaga
//
LOCUS       DAVBEM010000120          265 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVBEM010000120 DAVBEM010000000
VERSION     DAVBEM010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..265
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.120"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            complement(1..265)
                     /locus_tag="VQ548_002126"
                     /pseudo
     CDS             complement(1..265)
                     /locus_tag="VQ548_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT           84 a           42 c           55 g           84 t
ORIGIN      
        1 tgaaaaagca agagctgata gagttgatag tggtgtttca agtcttccga ataactcaaa
       61 agcttgttta aaatctcttt attggttcaa tgcatacgaa aagtaggacg ataaaaatgt
      121 ttatcactca gtttacgact atcctgttga atgagtttcc agtagcgctt gatagccttg
      181 tattcatggg attttcgatg aaactgattt atgatttgaa cacgcacacg actcatagca
      241 cggctaagat gttgtacaat gtgaa
//
LOCUS       DAVBEM010000121          229 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 019
            SAMEA1678096-rid20180783.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVBEM010000121 DAVBEM010000000
VERSION     DAVBEM010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678096
            Sequence Read Archive: ERR226394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980209.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:12:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,127
            CDSs (total)                      :: 2,089
            Genes (coding)                    :: 1,948
            CDSs (with protein)               :: 1,948
            Genes (RNA)                       :: 38
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 39 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..229
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678096-rid20180783.denovo.121"
                     /strain="KS 019"
                     /db_xref="taxon:1313"
     gene            <1..>229
                     /locus_tag="VQ548_002127"
     CDS             <1..>229
                     /locus_tag="VQ548_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2654890.1"
                     /translation="YTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHS
                     HWIKKDSLSEAERAAAQAYAKEKGLTPPSTDH"
BASE COUNT           72 a           49 c           55 g           53 t
ORIGIN      
        1 tacactgatg atgagattca agtagccaag ttggcaggca agtacacaac agaagacggt
       61 tatatctttg atcctcgtga tataaccagt gatgaggggg atgcctatgt aactccacat
      121 atgacccata gccactggat taaaaaagat agtttgtctg aagctgagag agcggcagcc
      181 caggcttatg ctaaagagaa aggtttgacc cctccttcga cagaccatc
//
